Works in mAbs, 2015, Vol 7, Issue 5

Results: 17

Engineered antibody domains with significantly increased transcytosis and half-life in macaques mediated by FcRn.

Published in:

mAbs (1942-0862), 2015, v. 7, n. 5, p. 922, doi. 10.1080/19420862.2015.1067353

By:

Ying, Tianlei;
Wang, Yanping;
Feng, Yang;
Prabakaran, Ponraj;
Gong, Rui;
Wang, Lili;
Crowder, Karalyne;
Dimitrov, Dimiter S

Publication type:

Article

Consistency of quality attributes for the glycosylated monoclonal antibody Humira® (adalimumab).

Published in:

mAbs (1942-0862), 2015, v. 7, n. 5, p. 805, doi. 10.1080/19420862.2015.1073429

By:

Tebbey, Paul W;
Varga, Amy;
Naill, Michael;
Clewell, Jerry;
Venema, Jaap

Publication type:

Article

Development of a quantitative mass spectrometry multi-attribute method for characterization, quality control testing and disposition of biologics.

Published in:

mAbs (1942-0862), 2015, v. 7, n. 5, p. 881, doi. 10.1080/19420862.2015.1069454

By:

Rogers, Richard S;
Nightlinger, Nancy S;
Livingston, Brittney;
Campbell, Phil;
Bailey, Robert;
Balland, Alain

Publication type:

Article

MoFvAb: Modeling the Fv region of antibodies.

Published in:

mAbs (1942-0862), 2015, v. 7, n. 5, p. 838, doi. 10.1080/19420862.2015.1068492

By:

Bujotzek, Alexander;
Fuchs, Angelika;
Qu, Changtao;
Benz, Jörg;
Klostermann, Stefan;
Antes, Iris;
Georges, Guy

Publication type:

Article

Increasing the potency of neutralizing single-domain antibodies by functionalization with a CD11b/CD18 binding domain.

Published in:

mAbs (1942-0862), 2015, v. 7, n. 5, p. 820, doi. 10.1080/19420862.2015.1068491

By:

Rossotti, Martin A;
González-Techera, Andrés;
Guarnaschelli, Julio;
Yim, Lucia;
Camacho, Ximena;
Fernández, Marcelo;
Cabral, Pablo;
Leizagoyen, Carmen;
Chabalgoity, José A;
González-Sapienza, Gualberto

Publication type:

Article

Targeting CD64 mediates elimination of M1 but not M2 macrophages in vitro and in cutaneous inflammation in mice and patient biopsies.

Published in:

mAbs (1942-0862), 2015, v. 7, n. 5, p. 853, doi. 10.1080/19420862.2015.1066950

By:

Hristodorov, Dmitrij;
Mladenov, Radoslav;
von Felbert, Verena;
Huhn, Michael;
Fischer, Rainer;
Barth, Stefan;
Thepen, Theo

Publication type:

Article

Functionalized micro-capillary film for the rapid at-line analysis of IgG aggregates in a cell culture bioreactor.

Published in:

mAbs (1942-0862), 2015, v. 7, n. 5, p. 812, doi. 10.1080/19420862.2015.1065365

By:

Townsend, Matthew J;
Gruber, David E;
Kuiper, Marcel;
Lazar, Radu A;
Field, Ray P;
Turner, Richard E;
Slater, Nigel KH

Publication type:

Article

Metal ion interactions with mAbs: Part 1.

Published in:

mAbs (1942-0862), 2015, v. 7, n. 5, p. 901, doi. 10.1080/19420862.2015.1062193

By:

Glover, Zephania Kwong;
Basa, Louisette;
Moore, Benjamin;
Laurence, Jennifer S;
Sreedhara, Alavattam

Publication type:

Article

A bispecific antibody targeting CD47 and CD20 selectively binds and eliminates dual antigen expressing lymphoma cells.

Published in:

mAbs (1942-0862), 2015, v. 7, n. 5, p. 946, doi. 10.1080/19420862.2015.1062192

By:

Piccione, Emily C;
Juarez, Silvia;
Liu, Jie;
Tseng, Serena;
Ryan, Christine E;
Narayanan, Cyndhavi;
Wang, Lijuan;
Weiskopf, Kipp;
Majeti, Ravindra

Publication type:

Article

Integrated pharmacokinetic, pharmacodynamic and immunogenicity profiling of an anti-CCL21 monoclonal antibody in cynomolgus monkeys.

Published in:

mAbs (1942-0862), 2015, v. 7, n. 5, p. 829, doi. 10.1080/19420862.2015.1060384

By:

Dudal, S;
Subramanian, K;
Flandre, T;
Law, WS;
Lowe, PJ;
Skerjanec, A;
Genin, J-C;
Duval, M;
Piequet, A;
Cordier, A;
Jarai, G;
Van Heeke, G;
Taplin, S;
Krantz, C;
Jones, S;
Warren, AP;
Brennan, FR;
Sims, J;
Lloyd, P

Publication type:

Article

Structure-guided residence time optimization of a dabigatran reversal agent.

Published in:

mAbs (1942-0862), 2015, v. 7, n. 5, p. 871, doi. 10.1080/19420862.2015.1057364

By:

Schiele, Felix;
van Ryn, Joanne;
Litzenburger, Tobias;
Ritter, Michael;
Seeliger, Daniel;
Nar, Herbert

Publication type:

Article

A fully human monoclonal antibody with novel binding epitope and excellent neutralizing activity to multiple human IFN-α subtypes: A candidate therapy for systemic lupus erythematosus.

Published in:

mAbs (1942-0862), 2015, v. 7, n. 5, p. 969, doi. 10.1080/19420862.2015.1055443

By:

Du, Peng;
Xu, Lei;
Qiu, Weiyi;
Zeng, Dadi;
Yue, Junjie;
Wang, Shuang;
Huang, Peitang;
Sun, Zhiwei

Publication type:

Article

A bi-functional antibody-receptor domain fusion protein simultaneously targeting IGF-IR and VEGF for degradation.

Published in:

mAbs (1942-0862), 2015, v. 7, n. 5, p. 931, doi. 10.1080/19420862.2015.1055442

By:

Shen, Yang;
Zeng, Lin;
Novosyadlyy, Ruslan;
Forest, Amelie;
Zhu, Aiping;
Korytko, Andrew;
Zhang, Haifan;
Eastman, Scott W;
Topper, Michael;
Hindi, Sagit;
Covino, Nicole;
Persaud, Kris;
Kang, Yun;
Burtrum, Douglas;
Surguladze, David;
Prewett, Marie;
Chintharlapalli, Sudhakar;
Wroblewski, Victor J;
Shen, Juqun;
Balderes, Paul

Publication type:

Article

A novel in vitro assay to predict neonatal Fc receptor-mediated human IgG half-life.

Published in:

mAbs (1942-0862), 2015, v. 7, n. 5, p. 912, doi. 10.1080/19420862.2015.1054585

By:

Souders, Colby A;
Nelson, Stuart C;
Wang, Yang;
Crowley, Andrew R;
Klempner, Mark S;
Thomas, William

Publication type:

Article

Processing of complex N-glycans in IgG Fc-region is affected by core fucosylation.

Published in:

mAbs (1942-0862), 2015, v. 7, n. 5, p. 863, doi. 10.1080/19420862.2015.1053683

By:

Castilho, Alexandra;
Gruber, Clemens;
Thader, Andreas;
Oostenbrink, Chris;
Pechlaner, Maria;
Steinkellner, Herta;
Altmann, Friedrich

Publication type:

Article

Functional assessment of antibody oxidation by native mass spectrometry.

Published in:

mAbs (1942-0862), 2015, v. 7, n. 5, p. 891, doi. 10.1080/19420862.2015.1052199

By:

Haberger, Markus;
Heidenreich, Anna-Katharina;
Schlothauer, Tilman;
Hook, Michaela;
Gassner, Jana;
Bomans, Katrin;
Yegres, Michelle;
Zwick, Adrian;
Zimmermann, Boris;
Wegele, Harald;
Bonnington, Lea;
Reusch, Dietmar;
Bulau, Patrick

Publication type:

Article

TTAC-0001, a human monoclonal antibody targeting VEGFR-2/KDR, blocks tumor angiogenesis.

Published in:

mAbs (1942-0862), 2015, v. 7, n. 5, p. 957, doi. 10.1080/19420862.2015.1045168

By:

Lee, Weon Sup;
Pyun, Bo-Jeong;
Kim, Sung-Woo;
Shim, Sang Ryeol;
Nam, Ju Ryoung;
Yoo, Ji Young;
Jin, Younggeon;
Jin, Juyoun;
Kwon, Young-Guen;
Yun, Chae-Ok;
Nam, Do-Hyun;
Oh, Keunhee;
Lee, Dong-Sup;
Lee, Sang Hoon;
Yoo, Jin-San

Publication type:

Article