Therapeutic blockade of CXCR2 rapidly clears inflammation in arthritis and atopic dermatitis models: demonstration with surrogate and humanized antibodies.
- Published in:
- 2020
- By:
- Publication type:
- Report
Works in mAbs (1942-0862), 2020, Vol 12, Issue 1
Results: 115
1
2
Identification and quantitation of hinge cysteinylation on endogenous IgG2 antibodies from human serum.
- Published in:
- 2020
- By:
- Publication type:
- Report
3
Anti-SARS-CoV-2 neutralizing monoclonal antibodies: clinical pipeline.
- Published in:
- mAbs (1942-0862), 2020, v. 12, n. 1, p. 1, doi. 10.1080/19420862.2020.1854149
- By:
- Publication type:
- Article
4
Monoclonal antibody 2C5 specifically targets neutrophil extracellular traps.
- Published in:
- 2020
- By:
- Publication type:
- Report
5
Rabbits transgenic for human IgG genes recapitulating rabbit B-cell biology to generate human antibodies of high specificity and affinity.
- Published in:
- 2020
- By:
- Publication type:
- Report
6
Diverse HIV-1 escape pathways from broadly neutralizing antibody PGDM1400 in humanized mice.
- Published in:
- mAbs (1942-0862), 2020, v. 12, n. 1, p. 1, doi. 10.1080/19420862.2020.1845908
- By:
- Publication type:
- Article
7
Impact of Fc N-linked glycans on in vivo clearance of an immunoglobulin G1 antibody produced by NS0 cell line.
- Published in:
- 2020
- By:
- Publication type:
- Report
8
Selection and verification of antibodies against the cytoplasmic domain of M2 of influenza, a transmembrane protein.
- Published in:
- 2020
- By:
- Publication type:
- Report
9
CAR-J cells for antibody discovery and lead optimization of TCR-like immunoglobulins.
- Published in:
- 2020
- By:
- Publication type:
- Report
10
Hiding in plain sight: structure and sequence analysis reveals the importance of the antibody DE loop for antibody-antigen binding.
- Published in:
- 2020
- By:
- Publication type:
- Report
11
Fully human anti-CD39 antibody potently inhibits ATPase activity in cancer cells via uncompetitive allosteric mechanism.
- Published in:
- 2020
- By:
- Publication type:
- Report
12
Removal of variable domain N-linked glycosylation as a means to improve the homogeneity of HIV-1 broadly neutralizing antibodies.
- Published in:
- 2020
- By:
- Publication type:
- Report
13
Isolation of monoclonal antibodies from anti-synthetase syndrome patients and affinity maturation by recombination of independent somatic variants.
- Published in:
- 2020
- By:
- Publication type:
- Report
14
A monoclonal antibody with broad specificity for the ligands of insulin B:9-23 reactive T cells prevents spontaneous type 1 diabetes in mice.
- Published in:
- 2020
- By:
- Publication type:
- Report
15
Novel human monoclonal antibodies specific to the alternatively spliced domain D of Tenascin C efficiently target tumors in vivo.
- Published in:
- 2020
- By:
- Publication type:
- Report
16
Vaccine-induced CD8 T cells are redirected with peptide-MHC class I-IgG antibody fusion proteins to eliminate tumor cells in vivo.
- Published in:
- 2020
- By:
- Publication type:
- Report
17
Cross-species/cross-modality physiologically based pharmacokinetics for biologics: 89Zr-labelled albumin-binding domain antibody GSK3128349 in humans.
- Published in:
- 2020
- By:
- Publication type:
- Report
18
Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody.
- Published in:
- 2020
- By:
- Publication type:
- Report
19
Design of next-generation therapeutic IgG4 with improved manufacturability and bioanalytical characteristics.
- Published in:
- mAbs (1942-0862), 2020, v. 12, n. 1, p. 1, doi. 10.1080/19420862.2020.1829338
- By:
- Publication type:
- Article
20
Pharmacokinetics of novel Fc-engineered monoclonal and multispecific antibodies in cynomolgus monkeys and humanized FcRn transgenic mouse models.
- Published in:
- 2020
- By:
- Publication type:
- Report
21
Optimization and kinetic modeling of interchain disulfide bond reoxidation of monoclonal antibodies in bioprocesses.
- Published in:
- 2020
- By:
- Publication type:
- Report
22
Beyond affinity: selection of antibody variants with optimal biophysical properties and reduced immunogenicity from mammalian display libraries.
- Published in:
- 2020
- By:
- Publication type:
- Report
23
Functional humanization of immunoglobulin heavy constant gamma 1 Fc domain human FCGRT transgenic mice.
- Published in:
- 2020
- By:
- Publication type:
- Report
24
On-column disulfide bond formation of monoclonal antibodies during Protein A chromatography eliminates low molecular weight species and rescues reduced antibodies.
- Published in:
- 2020
- By:
- Publication type:
- Report
25
Targeted IgMs agonize ocular targets with extended vitreal exposure.
- Published in:
- 2020
- By:
- Publication type:
- Report
26
Molecular computations of preferential interactions of proline, arginine.HCl, and NaCl with IgG1 antibodies and their impact on aggregation and viscosity.
- Published in:
- 2020
- By:
- Publication type:
- Report
27
An accelerated surface-mediated stress assay of antibody instability for developability studies.
- Published in:
- 2020
- By:
- Publication type:
- Report
28
Biased anti-idiotype response in rabbits leads to high-affinity monoclonal antibodies to biologics.
- Published in:
- 2020
- By:
- Publication type:
- Report
29
Engineered Fc-glycosylation switch to eliminate antibody effector function.
- Published in:
- 2020
- By:
- Publication type:
- Report
30
A minimal physiologically based pharmacokinetic model to characterize colon TNF suppression and treatment effects of an anti-TNF monoclonal antibody in a mouse inflammatory bowel disease model.
- Published in:
- 2020
- By:
- Publication type:
- Report
31
Biophysical and biochemical characterization of a VHH-based IgG-like bi- and trispecific antibody platform.
- Published in:
- 2020
- By:
- Publication type:
- Report
32
Measuring aggregates, self-association, and weak interactions in concentrated therapeutic antibody solutions.
- Published in:
- 2020
- By:
- Publication type:
- Report
33
CD40- and CD95-specific antibody single chain-Baff fusion proteins display BaffR-, TACI- and BCMA-restricted agonism.
- Published in:
- 2020
- By:
- Publication type:
- Report
34
A novel biparatopic hybrid antibody-ACE2 fusion that blocks SARS-CoV-2 infection: implications for therapy.
- Published in:
- mAbs (1942-0862), 2020, v. 12, n. 1, p. 1, doi. 10.1080/19420862.2020.1804241
- By:
- Publication type:
- Article
35
Affinity maturation of antibodies by combinatorial codon mutagenesis versus error-prone PCR.
- Published in:
- 2020
- By:
- Publication type:
- Report
36
Assessment of the role of afucosylated glycoforms on the in vitro antibody-dependent phagocytosis activity of an antibody to Aβ aggregates.
- Published in:
- 2020
- By:
- Publication type:
- Report
37
AlbuCORE: an albumin-based molecular scaffold for multivalent biologics design.
- Published in:
- 2020
- By:
- Publication type:
- Report
38
Novel monoclonal antibodies to the SERINC5 HIV-1 restriction factor detect endogenous and virion-associated SERINC5.
- Published in:
- 2020
- By:
- Publication type:
- Report
39
Antigen physiochemical properties allosterically effect the IgG Fc-region and Fc neonatal receptor affinity.
- Published in:
- 2020
- By:
- Publication type:
- Report
40
Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
- Published in:
- 2020
- By:
- Publication type:
- Report
41
Novel chimerized IgA CD20 antibodies: Improving neutrophil activation against CD20-positive malignancies.
- Published in:
- 2020
- By:
- Publication type:
- Report
42
Development and validation of an LC-MS/MS method for simultaneous quantification of co-administered trastuzumab and pertuzumab.
- Published in:
- 2020
- By:
- Publication type:
- Report
43
Conjugation of a peptide to an antibody engineered with free cysteines dramatically improves half-life and activity.
- Published in:
- 2020
- By:
- Publication type:
- Report
44
The Antibody Society's antibody validation webinar series.
- Published in:
- mAbs (1942-0862), 2020, v. 12, n. 1, p. 1, doi. 10.1080/19420862.2020.1794421
- By:
- Publication type:
- Article
45
Bivalent binding on cells varies between anti-CD20 antibodies and is dose-dependent.
- Published in:
- 2020
- By:
- Publication type:
- Report
46
COBRA™: a highly potent conditionally active T cell engager engineered for the treatment of solid tumors.
- Published in:
- 2020
- By:
- Publication type:
- Report
47
Malignant tissues produce divergent antibody glycosylation of relevance for cancer gene therapy effectiveness.
- Published in:
- 2020
- By:
- Publication type:
- Report
48
A general evidence-based sequence variant control limit for recombinant therapeutic protein development.
- Published in:
- 2020
- By:
- Publication type:
- Report
49
Rational optimization of a monoclonal antibody improves the aggregation propensity and enhances the CMC properties along the entire pharmaceutical process chain.
- Published in:
- 2020
- By:
- Publication type:
- Report
50
An evaluation of instrument types for mass spectrometry-based multi-attribute analysis of biotherapeutics.
- Published in:
- 2020
- By:
- Publication type:
- Report