Works in Journal of Experimental & Clinical Cancer Research (17569966), 2025, Vol 44, Issue 1

Results: 167

Correction: SH3GLB1-related autophagy mediates mitochondrial metabolism to acquire resistance against temozolomide in glioblastoma.

Published in:

2025

By:

Chien, Chia-Hung;
Yang, Wen-Bin;
Chuang, Jian-Ying;
Lee, Jung-Shun;
Liao, Wei-An;
Huang, Chih-Yuan;
Chen, Pin-Yuan;
Wu, An-Chih;
Yang, Shun-Tai;
Lai, Chien-Cheng;
Chi, Pei-I.;
Chu, Jui-Mei;
Cheng, Siao Muk;
Liu, Chan-Chuan;
Hwang, Daw-Yang;
Chen, Shang-Hung;
Chang, Kwang-Yu

Publication type:

Correction Notice

Baseline levels and dynamic changes of cfDNA, tumor fraction and mutations to anticipate the clinical course of small cell lung cancer (SCLC) patients treated with first-line atezolizumab and chemotherapy: an hypothesis generating study (CATS/ML43257).

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03434-3

By:

Pasello, Giulia;
Pigato, Giulia;
Scattolin, Daniela;
Lando, Stefania;
Potente, Sara;
Romualdi, Chiara;
Roma, Anna;
Resi, Maria Vittoria;
Frega, Stefano;
Ferro, Alessandra;
Maso, Alessandro Dal;
Bonanno, Laura;
Guarneri, Valentina;
Lazzarini, Elisabetta;
Indraccolo, Stefano

Publication type:

Article

ESRP1 exerts anti-tumor role by promoting ferroptosis in diffuse-type gastric cancer.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03435-2

By:

Xu, Kang;
Chen, Hao;
Zhu, Xingyu;
Li, Han;
Liu, Xinyu;
Sang, Yaodong;
Wang, Xiaohan;
Cui, Xiaoling;
Cai, Baoshan;
Shang, Liang;
Chong, Wei;
Li, Leping

Publication type:

Article

Improved tumor-type informed compared to tumor-informed mutation tracking for ctDNA detection and microscopic residual disease assessment in epithelial ovarian cancer.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03433-4

By:

Ben Sassi, Mehdi;
Azais, Henri;
Marcaillou, Charles;
Guibert, Sylvain;
Martin, Emmanuel;
Alexandre, Jérôme;
Benoit, Louise;
de Reynies, Aurélien;
Laude, Emilie;
Duong, Cam;
Medioni, Jacques;
Borghese, Bruno;
Bats, Anne-Sophie;
Taly, Valerie;
Laurent-Puig, Pierre

Publication type:

Article

PARP-1 as a novel target in endocrine-resistant breast cancer.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03441-4

By:

Zicarelli, Azzurra;
Talia, Marianna;
Lainé, Muriel;
Lappano, Rosamaria;
Maggiolini, Marcello;
Greene, Geoffrey L.

Publication type:

Article

CD70 CAR-T cells empowered by TS-2021 through ex vivo transduction show potent antitumor efficacy against glioblastoma.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03431-6

By:

Fang, Sheng;
Wu, Jiankun;
Liu, Yida;
Wang, Peiwen;
Yuan, Guiqiang;
Gao, Jiajia;
Zhang, Wenxin;
Zhang, Junwen;
Liu, Fusheng

Publication type:

Article

Tumor suppressor SLC9A2 inhibits colorectal cancer metastasis and reverses immunotherapy resistance by suppressing angiogenesis.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03422-7

By:

Zhang, Zizhen;
Liu, Shengde;
Xu, Ting;
Chen, Nan;
Liu, Cheng;
Yang, Hong;
Shi, Yuanmeng;
Li, Zhiwei;
Feng, Xujiao;
Yao, Yanhong;
Duan, Xiaorui;
Xu, Gehan;
Zhang, Cheng;
Wang, Zhenghang;
Li, Jian;
Shen, Lin

Publication type:

Article

Upfront blood microRNA test in LDCT-reluctant individuals: insights from the biomild trial.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03424-5

By:

Sozzi, Gabriella;
Sabia, Federica;
Rolli, Luigi;
Segale, Miriam;
Suatoni, Paola;
Zanghi, Anna;
Ruggirello, Margherita;
Marchianò, Alfonso;
Boeri, Mattia;
Pastorino, Ugo

Publication type:

Article

Biopiezoelectric-based nanomaterials; a promising strategy in cancer therapy.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03427-2

By:

Zuo, Tingting;
Dewanjee, Saikat;
Zhang, Chao;
Chakraborty, Pratik;
Lu, Wanxia;
Jha, Niraj Kumar;
Bhattacharya, Hiranmoy;
Gangopadhyay, Moumita;
Fleishman, Joshua;
Jha, Saurabh Kumar;
Chen, Zhe-Sheng

Publication type:

Article

PSMB10 maintains the stemness of chemotherapeutic drug-resistant leukemia cells by inhibiting senescence and cytotoxic T lymphocyte-mediated killing in a ubiquitinated degradation manner.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03420-9

By:

Ma, Xiao;
Li, Yingnan;
Wang, Di;
Niu, Jialan;
Li, Qian;
Chen, Ying;
Wang, Mengyuan;
Wen, Jin;
Liao, Chenxi;
Wang, Nan;
Zhang, Xiaolan;
Chang, Jiwei;
Yang, Jiayi;
Li, Lei;
Zou, Jing;
Peng, Danyue;
Liu, Lingbo

Publication type:

Article

Correction: Liquid biopsy in gynecological cancers: a translational framework from molecular insights to precision oncology and clinical practice.

Published in:

2025

By:

Martinelli, Canio;
Ercoli, Alfredo;
Vizzielli, Giuseppe;
Burk, Sharon Raffaella;
Cuomo, Maria;
Satasiya, Vrunda;
Kacem, Housem;
Braccia, Simone;
Mazzarotti, Giulio;
Miriello, Irene;
Tchamou, Manuela Nana;
Restaino, Stefano;
Arcieri, Martina;
Poli, Alice;
Tius, Veronica;
Parisi, Silvana;
Pergolizzi, Stefano;
Iatì, Giuseppe;
Nibali, Chiara Conti;
Pizzimenti, Cristina

Publication type:

Correction Notice

CHD1L in cancer and beyond: structure, oncogenic functions, and therapeutic potential.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03428-1

By:

Clune, Sophia;
Awolade, Paul;
Esquer, Hector;
Zhou, Qiong;
LaBarbera, Daniel V.

Publication type:

Article

Correction: CD36 enrichment in HER2-positive mesenchymal stem cells drives therapy refractoriness in breast cancer.

Published in:

2025

By:

Castagnoli, Lorenzo;
Franceschini, Alma;
Cancila, Valeria;
Dugo, Matteo;
Bigliardi, Martina;
Chiodoni, Claudia;
Toneguzzo, Paolo;
Regondi, Viola;
Corsetto, Paola A.;
Pietrantonio, Filippo;
Mazzucchelli, Serena;
Corsi, Fabio;
Belfiore, Antonino;
Vingiani, Andrea;
Pruneri, Giancarlo;
Ligorio, Francesca;
Colombo, Mario P.;
Tagliabue, Elda;
Tripodo, Claudio;
Vernieri, Claudio

Publication type:

Correction Notice

Co-inhibition of Notch1 and ChK1 triggers genomic instability and melanoma cell death increasing the lifespan of mice bearing melanoma brain metastasis.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03411-w

By:

Thakur, Varsha;
Thakur, Vijay S.;
Wang, Dazhi;
de Freitas, Juliano Tiburcio;
Bianchi, Anna;
Nivelo, Luis Alberto;
Umland, Oliver;
Welford, Scott M.;
Bedogni, Barbara

Publication type:

Article

Acetylation-induced degradation of ECHS1 enhances BCAA accumulation and proliferation in KRAS-mutant colorectal cancer.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03399-3

By:

Li, Zhenkang;
Liu, Zhengyu;
Lin, Mingdao;
Pan, Huayang;
Liu, Yuechen;
Liu, Yang;
Xie, Yuwen;
Zhang, Jinchao;
Guan, Shenyuan;
Li, Yongsheng;
Zhu, Mulan;
Fang, Yuan;
Shen, Zhiyong;
Deng, Haijun

Publication type:

Article

Periostin-mediated NOTCH1 activation between tumor cells and HSCs crosstalk promotes liver metastasis of small cell lung cancer.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-024-03266-7

By:

Lou, Linlin;
Peng, Keren;
Ouyang, Shumin;
Ding, Wen;
Mo, Jianshan;
Yan, Jiayu;
Gong, Xiaoxiao;
Liu, Guopin;
Lu, Jinjian;
Yue, Peibin;
Zhang, Kai;
Zhang, Jian;
Wang, Yan-dong;
Zhang, Xiao-lei

Publication type:

Article

Tumour-associated macrophage infiltration differs in meningioma genotypes, and is important in tumour dynamics.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03419-2

By:

Zhang, Ting;
Adams, Claire L.;
Fejer, Gyorgy;
Ercolano, Emanuela;
Cutajar, Jonathan;
Na, Juri;
Sahm, Felix;
Hanemann, C. Oliver

Publication type:

Article

Correction: Targeted Inhibition of PDGFRA with avapritinib, markedly enhances lenvatinib efficacy in hepatocellular carcinoma in vitro and in vivo: clinical implications.

Published in:

2025

By:

Zhao, Bixing;
Zhou, Yang;
Cheng, Niangmei;
Zheng, Xiaoyuan;
Chen, Geng;
Qi, Xin;
Zhang, Xiangzhi;
Wang, Fei;
Zhuang, Qiuyu;
Assaraf, Yehuda G.;
Liu, Xiaolong;
Wang, Yingchao;
Zeng, Yongyi

Publication type:

Correction Notice

Enhancing radiosensitivity of osteosarcoma by ITGB3 knockdown: a mechanism linked to enhanced osteogenic differentiation status through JNK/c-JUN/RUNX2 pathway activation.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03417-4

By:

Lian, Qiujian;
Liu, Hu;
Li, Jingyan;
Luo, Cheng;
Liu, Chang;
Zhao, Haonan;
Dai, Peijun;
Wang, Bingxuan;
Zhou, Huipeng;
Jiang, Xin;
Wang, Zhiwei;
Qiao, Suchi

Publication type:

Article

An antibody-drug conjugate targeting soluble and membrane-bound TGFα is effective against pancreatic tumors.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03421-8

By:

Romero-Pérez, Inés;
Montero, Juan Carlos;
Redondo-Puente, Mónica;
del Carmen Gómez-García, María;
Morell-Ginestà, Mireia;
Capellá, Gabriel;
Pandiella, Atanasio

Publication type:

Article

Characterization of extracellular vesicle-associated DNA and proteins derived from organotropic metastatic breast cancer cells.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03418-3

By:

Nadeau, Amélie;
Tsering, Thupten;
Abdouh, Mohamed;
Kienzle, Laura;
Cleyle, Jenna;
Taylor, Lorne;
Douanne, Noélie;
Dickinson, Kyle;
Siegel, Peter M.;
Burnier, Julia V.

Publication type:

Article

Fostering the implementation of liquid biopsy in clinical practice: meeting report 2024 of the European Liquid Biopsy Society (ELBS).

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03398-4

By:

Pantel, Klaus;
Alix-Panabières, Catherine;
Hofman, Paul;
Stoecklein, Nikolas H.;
Lu, Yong-Jie;
Lianidou, Evi;
Giacomini, Patrizio;
Koch, Claudia;
de Jager, Vincent;
Deans, Zandra C.;
Fairley, Jennifer;
Patton, Simon J.;
Toledo, Rodrigo A.;
Schuuring, Ed;
Heitzer, Ellen;
Hendrix, An;
Ricklefs, Franz Lennard;
Thakur, Basant Kumar;
von Bubnoff, Nikolas;
Pierga, Jean-Yves

Publication type:

Article

HBV sequence integrated to enhancer acting as oncogenic driver epigenetically promotes hepatocellular carcinoma development.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03413-8

By:

Chen, Lu;
Li, Wenxuan;
Zai, Wenjing;
Zheng, Xiangyi;
Meng, Xianlong;
Yao, Qunyan;
Li, Wei;
Liang, Ying;
Ye, Mu;
Zhou, Kaicheng;
Liu, Mengxing;
Yang, Zhicong;
Mao, Zhanrui;
Wei, Hongyan;
Yang, Shuai;
Shi, Guoming;
Yuan, Zhenghong;
Yu, Wenqiang

Publication type:

Article

AP1-mediated reprogramming of EGFR expression triggers resistance to BLU-667 and LOXO-292 in RET-rearranged tumors.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03392-w

By:

Esposito, Daniela;
Ascione, Claudia Maria;
Belli, Stefania;
Napolitano, Fabiana;
Servetto, Alberto;
Pepe, Felice;
Malapelle, Umberto;
Iaccarino, Antonino;
Troncone, Giancarlo;
Barone, Diletta;
Bria, Emilio;
Ferrara, Roberto;
Lorenzini, Daniele;
Lo Russo, Giuseppe;
Ghigna, Maria Rosa;
Marinello, Arianna;
Aldea, Mihaela;
Besse, Benjamin;
Formisano, Luigi;
Bianco, Roberto

Publication type:

Article

HHLA2 activates c-Met and identifies patients for targeted therapy in hepatocellular carcinoma.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03407-6

By:

Huang, Xubo;
Fang, Runya;
Pang, Yuqian;
Zhang, Zhe;
Huang, Jieru;
Li, Yingchang;
Yuan, Tao;
Zeng, Yuyi;
Yao, Ziying;
Vega-Rubín-de-Celis, Silvia;
Thinwa, Josephine;
Zhang, Qisheng;
Shen, Hao;
Wang, Jiahong;
Shen, Feng;
Wei, Yongjie

Publication type:

Article

Correction: Long non-coding RNA NKILA inhibits migration and invasion of non-small cell lung cancer via NF-κB/Snail pathway.

Published in:

2025

By:

Lu, Zhiliang;
Li, Yuan;
Wang, Jingnan;
Che, Yun;
Sun, Shouguo;
Huang, Jianbing;
Chen, Zhaoli;
He, Jie

Publication type:

Correction Notice

Antitumor activity of rucaparib plus PLX038A in serous endometrial carcinoma.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03406-7

By:

Hou, Xiaonan;
Zanfagnin, Valentina;
Xu, Conway;
Jessen, Erik;
Liu, Yuanhang;
Wang, Chen;
Huang, Yajue;
Fontaine, Shaun D.;
Santi, Daniel V.;
Colon-Otero, Gerardo;
Gill, Sarah E.;
Glaser, Gretchen E.;
Butler, Kristina A.;
Bakkum-Gamez, Jamie N.;
Dowdy, Sean C.;
Oberg, Ann L.;
Larson, Melissa C.;
Atkinson, Hunter J.;
Duffield, Laura N.;
Peterson, Kevin L.

Publication type:

Article

ANXA1 promotes intrahepatic cholangiocarcinoma proliferation and growth by regulating glutamine metabolism through GOT1 stabilization.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03400-z

By:

Gong, Yanyu;
Chen, Liwen;
Wang, Hao;
Zheng, Dijie;
Li, Futang;
Wu, Changhao;
Li, Yongning;
Deng, Yazhu;
He, Zhiwei;
Yu, Chao

Publication type:

Article

Novel Pt@PCN-Cu-induced cuproptosis amplifies αPD-L1 immunotherapy in pancreatic ductal adenocarcinoma through mitochondrial HK2-mediated PD-L1 upregulation.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03409-4

By:

Wang, Pengyu;
Guo, Weihua;
Liu, Shuyue;
Li, Shouyi;
Li, Jiaqi;
Ding, Bowen;
Yin, Fengyi;
Yang, Yang;
Li, Xingjiang;
Cao, Pei;
Ma, Chaozhe;
Zhang, Wanying;
Song, Yidan;
Geng, Yating;
Liu, Lantao;
Hu, Jing;
Hao, Jihui;
Feng, Yukuan

Publication type:

Article

HBV-driven host chromatin accessibility changes affect liver metabolic pathways, iron homeostasis and promote a preneoplastic phenotype.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03414-7

By:

Alfano, Vincenzo;
Pascucci, Giuseppe Rubens;
Corleone, Giacomo;
Cocca, Massimiliano;
De Nicola, Francesca;
Floriot, Océane;
Paturel, Alexia;
Di Tocco, Francesca Casuscelli;
de Fromentel, Claude Caron;
Merle, Philippe;
Rivoire, Michel;
Levrero, Massimo;
Guerrieri, Francesca

Publication type:

Article

Light-activatable manganese carbonate nanocubes elicit robust immunotherapy by amplifying endoplasmic reticulum stress-meditated pyroptotic cell death.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03408-5

By:

Wu, Chuan;
Gao, Mingquan;
Xiao, Weidong;
Huang, Xie;
Yang, Xinrui;
Wu, Zifei;
Yu, Xudong;
Mo, Banghui;
Du, Zaizhi;
Shang, Ziqian;
Liu, Jing;
Shi, Can;
Li, Rong;
Luo, Shenglin;
Wang, Weidong

Publication type:

Article

A novel pH-sensitive nanoparticles encapsulating anti-PD-1 antibody and MDK-siRNA overcome immune checkpoint blockade resistance in HCC via reshaping immunosuppressive TME.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03396-6

By:

Xu, Hai;
Li, Shuo;
Liu, Yifan;
Sung, Yoon-Young;
Zhou, Yong;
Wu, Huikun

Publication type:

Article

Genome-Wide Methylation Sequencing to Identify DNA Methylation Markers for Early-stage Hepatocellular Carcinoma in Liver and Blood.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03412-9

By:

Fu, Siyu;
Boers, Ruben G.;
Boers, Joachim B.;
van der Meeren, Pam E.;
Helmijr, Jean;
de Weerd, Vanja;
Doukas, Michail;
Jansen, Maurice;
Hansen, Bettina E.;
de Wilde, Roeland F.;
Sprengers, Dave;
Gribnau, Joost;
Wilting, Saskia M.;
Debes, José D.;
Boonstra, Andre

Publication type:

Article

Comparative analysis of circulating tumor cells in prostatic plexus and peripheral blood of patients undergoing prostatectomy.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03397-5

By:

Emurlai, Gresa;
Pose, Randi M.;
Kalra, Nikhil;
Coith, Cornelia;
Lenz, Sandra;
Tennstedt, Pierre;
Graefen, Markus;
Werner, Stefan;
Riethdorf, Sabine;
Tilki, Derya;
Joosse, Simon A.;
Pantel, Klaus

Publication type:

Article

Tie2 activity in cancer associated myofibroblasts serves as novel target against reprogramming of cancer cells to embryonic-like cell state and associated poor prognosis in oral carcinoma patients.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03405-8

By:

Mitra, Paromita;
Saha, Uday;
Stephen, Kingsly Joshua;
Prasad, Priyanka;
Jena, Subhashree;
Patel, Ankit Kumar;
BV, Harshavardhan;
Mondal, Santosh Kumar;
Kurkalang, Sillarine;
Roy, Sumitava;
Ghosh, Arnab;
Roy, Shantanu Saha;
Das Sarma, Jayasri;
Biswas, Nidhan Kumar;
Acharya, Moulinath;
Sharan, Rajeev;
Arun, Pattatheyil;
Jolly, Mohit Kumar;
Maitra, Arindam;
Singh, Sandeep

Publication type:

Article

Tumor cell-intrinsic BIN1 deficiency promotes the immunosuppression and impedes ferroptosis of non-small cell lung cancer via G3BP1-mediated degradation of STAT1.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03404-9

By:

Wang, Jiali;
Jia, Yunlong;
Liu, Tianxu;
Liu, Xinyan;
Yin, Shuxian;
Chen, Jiaqi;
Xu, Xiaoqing;
Zhang, Yi;
Liu, Lihua

Publication type:

Article

Liquid biopsy in gynecological cancers: a translational framework from molecular insights to precision oncology and clinical practice.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03371-1

By:

Martinelli, Canio;
Ercoli, Alfredo;
Vizzielli, Giuseppe;
Burk, Sharon Raffaella;
Cuomo, Maria;
Satasiya, Vrunda;
Kacem, Housem;
Braccia, Simone;
Mazzarotti, Giulio;
Miriello, Irene;
Tchamou, Manuela Nana;
Restaino, Stefano;
Arcieri, Martina;
Poli, Alice;
Tius, Veronica;
Parisi, Silvana;
Pergolizzi, Stefano;
Iatì, Giuseppe;
Nibali, Chiara Conti;
Pizzimenti, Cristina

Publication type:

Article

Targeted inhibition of PDGFRA with avapritinib, markedly enhances lenvatinib efficacy in hepatocellular carcinoma in vitro and in vivo: clinical implications.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03386-8

By:

Zhao, Bixing;
Zhou, Yang;
Cheng, Niangmei;
Zheng, Xiaoyuan;
Chen, Geng;
Qi, Xin;
Zhang, Xiangzhi;
Wang, Fei;
Zhuang, Qiuyu;
Assaraf, Yehuda G.;
Liu, Xiaolong;
Wang, Yingchao;
Zeng, Yongyi

Publication type:

Article

Harnessing engineered extracellular vesicles for enhanced therapeutic efficacy: advancements in cancer immunotherapy.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03403-w

By:

Gong, Zheng;
Cheng, Cheng;
Sun, Chaonan;
Cheng, Xiaoli

Publication type:

Article

Decitabine co-operates with the IL-33/ST2 axis modifying the tumor microenvironment and improving the response to PD-1 blockade in melanoma.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03381-z

By:

Noto, Francesco;
Mancini, Jacopo;
Gambardella, Adriana Rosa;
Curcio, Christina;
De Ninno, Adele;
Andreone, Sara;
Buccione, Carla;
D'Urso, Maria Teresa;
Macchia, Daniele;
Pacca, Anna Maria;
Spada, Massimo;
Businaro, Luca;
Afferni, Claudia;
Mattei, Fabrizio;
Schiavoni, Giovanna

Publication type:

Article

Extracellular vesicle digital scoring assay for assessment of treatment responses in hepatocellular carcinoma patients.

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Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03379-7

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Zhao, Chen;
Lee, Yi-Te;
Melehy, Andrew;
Kim, Minhyung;
Yang, Jacqueline Ziqian;
Zhang, Ceng;
Kim, Jina;
Zhang, Ryan Y.;
Lee, Junseok;
Kim, Hyoyong;
Ju, Yong;
Tsai, Yuan-Jen;
Zhou, Xianghong Jasmine;
Han, Steven-Huy B.;
Sadeghi, Saeed;
Finn, Richard S.;
Saab, Sammy;
Lu, David S.;
Chiang, Jason;
Park, Jae-Ho

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Epithelial-to-mesenchymal transition drives cancer genomic instability.

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Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03402-x

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Carstens, Julienne L.;
Lovisa, Sara

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Targeting the HLA-E–NKG2A axis in combination with MS-275 enhances NK cell-based immunotherapy against DMG.

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Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03390-y

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Deng, Yuxuan;
Liu, Jinqiu;
Pu, Zhuonan;
Wang, Yi;
Li, Tian;
Jiang, Zhuang;
Xie, Luyang;
Zhang, Xiaoli;
Chen, YingDan;
Yang, Mingxu;
Du, Chao;
Hao, Shuyu;
Ji, Nan;
Zhuang, Zhengping;
Feng, Jie;
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Reprogramming the breast tumor immune microenvironment: cold-to-hot transition for enhanced immunotherapy.

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Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03394-8

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Imani, Saber;
Farghadani, Reyhaneh;
Roozitalab, Ghazaal;
Maghsoudloo, Mazaher;
Emadi, Mahdieh;
Moradi, Atefeh;
Abedi, Behnaz;
Jabbarzadeh Kaboli, Parham

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7aaRGD - a novel SPP1/integrin signaling-blocking peptide reverses immunosuppression and improves anti-PD-1 immunotherapy outcomes in experimental gliomas.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03393-9

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Ellert-Miklaszewska, Aleksandra;
Pilanc, Paulina;
Poleszak, Katarzyna;
Roura, Adria-Jaume;
Cyranowski, Salwador;
Ghosh, Mitrajit;
Baluszek, Szymon;
Pasierbinska, Maria;
Gielniewski, Bartłomiej;
Swatler, Julian;
Hovorova, Yuliana;
Wojnicki, Kamil;
Kaminska, Bozena

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Exploring RNA binding proteins in hepatocellular carcinoma: insights into mechanisms and therapeutic potential.

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Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03395-7

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Ren, Xing;
Yang, Wenna;
Yan, Xiuli;
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A first-in-class inhibitor of homologous recombination DNA repair counteracts tumour growth, metastasis and therapeutic resistance in pancreatic cancer.

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Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03389-5

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Calheiros, Juliana;
Silva, Rita;
Barbosa, Filipa;
Morais, João;
Moura, Sara Reis;
Almeida, Sofia;
Fiorini, Elena;
Mulhovo, Silva;
Aguiar, Tatiana Q.;
Wang, Tao;
Ricardo, Sara;
Almeida, Maria Inês;
Domingues, Lucília;
Melo, Sonia A.;
Corbo, Vincenzo;
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Advanced organoid models for targeting Kras-driven lung adenocarcinoma in drug discovery and combination therapy.

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Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03385-9

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Taş, İsa;
Jacobs, Ruben;
Albrecht, Juliane;
Barrientos, Sebastian A.;
Åberg, Josephine;
Sime, Wondossen;
Brunnström, Hans;
Persson, Helena;
Kazi, Julhash U.;
Massoumi, Ramin

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Identification and characterization of tumor and stromal derived liquid biopsy analytes in pancreatic ductal adenocarcinoma.

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Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-024-03262-x

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Götze, Julian;
Meißner, Kira;
Pereira-Veiga, Thais;
Belloum, Yassine;
Schneegans, Svenja;
Kropidlowski, Jolanthe;
Gorgulho, Joao;
Busch, Alina;
Honselmann, Kim Christin;
Schönrock, Martin;
Putscher, Arne;
Peine, Sven;
Nitschke, Christine;
Simon, Ronald;
Spindler, Volker;
Izbicki, Jakob Robert;
Hackert, Thilo;
Bokemeyer, Carsten;
Pantel, Klaus;
Uzunoglu, Faik Güntaç

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Article

MicroRNA in cancer therapy: breakthroughs and challenges in early clinical applications.

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Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03391-x

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Martino, Maria Teresa Di;
Tagliaferri, Pierosandro;
Tassone, Pierfrancesco

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