Works in Frontiers in Immunology, 2025

Results: 3406

Editorial: A new perspective in immune polymorphism (the HLA, KIR, and LILR genes).

Published in:

2025

By:

Khor, Seik-Soon;
Maiers, Martin;
Krawic, Jason;
Augusto, Danillo G.;
Souquette, Aisha

Publication type:

Editorial

Editorial: Combination immunotherapy and immune response assessment of brain tumours.

Published in:

2025

By:

Jiang, Haihui

Publication type:

Editorial

Harnessing extracellular vesicles to tame inflammation: a new strategy for atherosclerosis therapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1625958

By:

Li, Jiawei;
Wen, Tianliang;
Li, Xiaoran;
Cheng, Ruoyao;
Shen, Junyi;
Wang, Xin;
Guo, Zhaoqi;
Teng, Zhengjie;
Yi, Lin;
Zhang, Fan

Publication type:

Article

The differential role of IL-33 and IL-38 in prostate cancer, contradictory roles.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1623038

By:

Ban, Runfen;
Gao, Shanshan;
Zhou, Bin;
Bao, Shisan

Publication type:

Article

Peptidoglycan derived from Lacticaseibacillus rhamnosus and Lactobacillus acidophilus suppress TLR2/1-mediated inflammation in bovine endometrial epithelial cells.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1622307

By:

Waehama, Elham;
Fukuda, Kenji;
Mansouri, Alireza;
Hulugalla, Malinda;
Akthar, Ihshan;
Yousef, Mohamed Samy;
Miyamoto, Akio

Publication type:

Article

Pro-inflammatory granzyme K contributes extracellularly to disease.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1620670

By:

Turner, Christopher T.

Publication type:

Article

Myelin oligodendrocyte glycoprotein antibody-associated cerebral cortical encephalitis: a case report highlighting diagnostic challenges and therapeutic implications.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1619807

By:

Liu, MengChan;
Li, DaWei

Publication type:

Article

A comprehensive welfare scoring system for graft versus host disease clinical assessment in humanised mouse models used for pharmaceutical research.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1617528

By:

Nowak, Alice;
Marlow, Rebecca;
Ryan, Kelli;
Lapointe, Jean-Martin;
Sutton, Daniel;
Sharpe, Alan;
Crook, Lucy;
Walker, Jennifer A.;
Little, Emma;
Peverill, John;
Holberry-Brown, Adam;
Wassell, Emma;
McLaren-Jones, Robbie;
Cavanagh, Chelsea;
Dobre, Alex Vlad;
Baker, Tamara;
Clayton, Matthew;
Karp, Natasha A.;
Plugge, Michiel;
Thomas, Aurélie A.

Publication type:

Article

Decoding neuroinflammation in Alzheimer's disease: a multi-omics and AI-driven perspective for precision medicine.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1616899

By:

Lin, Shiyu;
Zhan, Yijun;
Wang, Ruiqi;
Pei, Jian

Publication type:

Article

Targeting fibroblast activation protein in rheumatoid arthritis: from molecular imaging to precision therapeutics.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1616618

By:

Huang, Yupeng;
Wu, Yang;
Liu, Huan;
Chen, Yuehong;
Xie, Qibing;
Yin, Geng

Publication type:

Article

Mesoporous silica nanoparticles loaded Au nanodots: a self-amplifying immunotherapeutic depot for photothermal immunotherapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1616539

By:

Wang, Chuan;
Wang, Dongmei;
Huang, Liang;
An, Qi

Publication type:

Article

Functional feed ingredients modulate the immune response of RTgutGC cells to LPS-induced inflammation.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1616076

By:

Fosse, Malene Malchus;
Méndez, Laura Rivera;
Rodríguez-Ramos, Tania;
Dixon, Brian;
Sundh, Henrik;
Olsen, Rolf Erik

Publication type:

Article

The functional and clinical significance of nucleoporin NUP153 across human cancers: a systematic study based on multi-omics analysis and bench work validation.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1613688

By:

He, Youfu;
Wang, Qing;
Wang, Zhaorui;
Duan, Menghui;
Zhou, Yu;
Huang, Jing;
Wu, Qiang;
Wu, Feichang;
Li, Chen

Publication type:

Article

Characterization and functional evaluation of JS207, a novel bispecific antibody against human PD-1 and VEGFA.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1612547

By:

Lin, Shihua;
Hong, Min;
Zhang, Jing;
Zhao, Wenting;
Li, Ke;
Wu, Chun;
Yang, Qiuyun;
Xiao, Yi;
Huang, Lanqing;
Wang, Jing;
Jia, Aijuan;
Wang, Xujia;
Yao, Sheng

Publication type:

Article

Revisiting pulmonary fibrosis: inflammatory dynamics of the lipofibroblast-to-inflammatory lipofibroblast-to-activated myofibroblast reversible switch.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1609509

By:

Panagiotidis, Georgios-Dimitrios;
Vasquez-Pacheco, Esmeralda;
Chu, Xuran;
Seeger, Werner;
El Agha, Elie;
Bellusci, Saverio;
Lingampally, Arun

Publication type:

Article

Immunogenicity of therapeutic peptide products: bridging the gaps regarding the role of product-related risk factors.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1608401

By:

Puig, Montserrat;
Shubow, Sophie

Publication type:

Article

Subtype-specific atypical B cell profiles in myasthenia gravis reveal distinct immunopathological pathways.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1608160

By:

Sikorski, Patricia M.;
Kaminski, Henry J.;
Vincent, Angela;
Bauman, Taylor;
Jacobson, Leslie;
Kusner, Linda L.

Publication type:

Article

The novel functions of chemokines in lung cancer progression.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1607225

By:

Gong, Xiaorui;
Wang, Xueying;
Jin, Jing;
Gong, Zhiqiang

Publication type:

Article

Single-cell analysis of peripheral blood and pleural effusion reveals functional diversity of γδ T cells in tuberculosis infection.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1605827

By:

Feng, Yanjun;
Chen, Yu;
Zhang, Wanying;
Shen, Xinghua;
Yan, Jinyu;
Yao, Lin;
Zhang, Lijuan;
Niu, Yayan;
Zhang, Jianping;
Tang, Peijun;
Ling, Chunhua

Publication type:

Article

Modulation of glucocorticoid receptor function under iron overload.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1605420

By:

Zhu, Wanting;
Vanderhaeghen, Tineke;
Timmermans, Steven;
Vandewalle, Jolien;
Eggermont, Melanie;
Verhoog, Nicolette J. D.;
Libert, Claude

Publication type:

Article

The processed Sanguisorba officinalis L. triterpenoids prevent colon cancer through the TNF- α /NF-κB signaling pathway, combined with network pharmacology, molecular simulation dynamics and experimental verification.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1605326

By:

Gan, Chunli;
Mu, Yuanqiu;
Ali, Shah Syed Faizan;
Shi, Xuepeng;
Jiang, Shuang;
Wang, Zhengyang;
Wu, Xiaotian;
Wang, Xiaotong;
Wang, Zhibin;
Zhang, Shulu;
Feng, Zheng;
Yang, Chunjuan

Publication type:

Article

Adaptive dynamic ϵ-simulated annealing algorithm for tumor immunotherapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1603551

By:

Sun, Xiaoyan;
Jiang, Ying

Publication type:

Article

The emerging relationship between mucosal-associated invariant T cell populations and the onset and progression of type 1 diabetes.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1602934

By:

Fraser, Devin R.;
Stadnyk, Andrew W.

Publication type:

Article

The plasma proteome reveals distinct signaling pathways associated with PR3-ANCA positive and MPO-ANCA positive vasculitis.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1600754

By:

Hellbacher, Erik;
van Hoef, Vincent;
Johansson, Alina;
Knight, Ann;
Gunnarsson, Iva;
Bruchfeld, Annette;
Eriksson, Per;
Ohlsson, Sophie;
Rantapää-Dahlqvist, Solbritt;
Dahlqvist, Johanna

Publication type:

Article

Identification and validation of NETs-related biomarkers in active tuberculosis through bioinformatics analysis and machine learning algorithms.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1599667

By:

Xia, Shengfang;
An, Qi;
Lin, Rui;
Tu, Yalan;
Chen, Zhu;
Wang, Dongmei

Publication type:

Article

Immunopathological features of highly pathogenic Korean Lineage B PRRSV-2: insights into virulence indicators and host immune responses.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1599468

By:

Park, Gyeong-Seo;
Kim, Seung-Chai;
Kim, Hwan-Ju;
Jeong, Chang-Gi;
Kang, Sang-Chul;
Shin, Go-Eun;
Kim, Seoung-Hee;
Jeong, Hye-Young;
Lee, Kyoung-Ki;
Lee, Sang-Myeong;
Kim, Won-Il

Publication type:

Article

Wuhan strain of SARS-CoV-2 triggers activation of immune evasion machinery similar to the one operated by cancer cells.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1599352

By:

Abooali, Maryam;
Yasinska, Inna M.;
Thapa, Gauri;
Lei, Xi;
da Costa, Kelly A. S.;
Schlichtner, Stephanie;
Berger, Steffen M.;
Fasler-Kan, Elizaveta;
Temperton, Nigel J.;
Vuono, Romina;
Sumbayev, Vadim V.

Publication type:

Article

Inflammation-driven periostin in ECRS has contrasting effects on tissue structural integrity and osteitis.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1596746

By:

Kim, Soo-In;
Rha, Min-Seok;
Kim, Jinsun;
Ahn, Sang Hyeon;
Ryu, Ji-Hwan;
Cho, Hyung-Ju;
Kim, Chang-Hoon

Publication type:

Article

Evaluating the immunogenicity of a mouse partial hindlimb for composite allotransplantation.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1595319

By:

Sun, Jia Hui;
Ligi, Samantha;
Biniazan, Felor;
Haykal, Siba

Publication type:

Article

The contribution of BTK signaling in myeloid cells to neuroinflammation.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1595069

By:

Bassani, Claudia;
Molinari, Marta;
Romeo, Valentina;
Martinelli, Vittorio;
Boschert, Ursula;
Martino, Gianvito;
Muzio, Luca;
Farina, Cinthia

Publication type:

Article

The efficacy and safety of tislelizumab with or without tyrosine kinase inhibitor as adjuvant therapy in hepatocellular carcinoma with high-risk of recurrence after curative resection.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1593153

By:

Peng, Ning;
Mao, Lin-Feng;
Su, Jia-Yong;
Liu, Shao-Ping;
Ou, Jun-Jie;
Chen, Shu-Chang;
Su, Ze;
Li, Wen-Feng;
Yang, Fu-Quan;
Zhou, Yong-Heng;
Li, Le;
Zhong, Jian-Hong

Publication type:

Article

The dual regulatory effects of intestinal microorganisms and their metabolites in gouty arthritis pathogenesis: a balance between promotion and inhibition.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1591369

By:

Qi, Peng;
Li, Longcan;
Zhang, Jianrong;
Ren, Ling;
Xie, Xingwen

Publication type:

Article

Integrative multi-omics analysis of IFNγ-induced macrophages and atherosclerotic plaques reveals macrophage-dependent STAT1-driven transcription in atherosclerosis.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1590953

By:

Eskandarian Boroujeni, Mahdi;
Lopacinska, Natalia;
Antonczyk, Aleksandra;
Kluzek, Katarzyna;
Wesoly, Joanna;
Bluyssen, Hans A. R.

Publication type:

Article

CCR5 gene editing and HIV immunotherapy: current understandings, challenges, and future directions.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1590690

By:

Wang, Jia-Wen;
Liu, Jia-Hui;
Xun, Jian-Jun

Publication type:

Article

Neutrophil-lymphocyte and platelet-lymphocyte ratios as systemic inflammatory biomarkers for atopic dermatitis in US adults: a cross-sectional NHANES study revealing subgroup heterogeneity.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1585451

By:

Chen, Xuanlin;
Yang, Xiangyu;
Zhang, Min;
Zhao, Yirui;
Guo, Shuping

Publication type:

Article

Interplay between tumor cells and immune cells of the colorectal cancer tumor microenvironment: Wnt/β-catenin pathway.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1587950

By:

Janeeh, Aisha Saleh;
Bajbouj, Khuloud;
Rah, Bilal;
Abu-Gharbieh, Eman;
Hamad, Mawieh

Publication type:

Article

ER stress genes (COL1A1, LOXL2, VWF) predicts IKK-16 as a Candidate therapeutic target for colitis-related inflammation and fibrosis suppression.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1587860

By:

Zhang, Ke;
Yang, Jiao;
Yang, Qing-Qing;
Guo, Jun-An;
Huang, Qian-Hui;
Cui, Chan;
Wang, Yue-Mei;
Wu, Qiao-Feng;
Wang, Jun-Meng

Publication type:

Article

Integrative analysis of T cell-associated markers in Ewing sarcoma reveals prognostic signatures and immune dynamics.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1586544

By:

Saddozai, Umair Ali Khan;
Liu, Chenxu;
Yan, Fei;
Lu, Zhendong;
Khawar, Muhammad Babar;
Akbar, Muhammad Usman;
Khattak, Saadullah;
Sun, Haibo;
Yang, Ping

Publication type:

Article

Complete recovery after complement factor I deficiency associated fulminant acute hemorrhagic leukoencephalitis: a case report.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1586288

By:

Szumutku, Fanni;
Szabó, Léna;
Liptai, Zoltán;
Varga, Edit;
Seszták, Tímea;
Barsi, Péter;
Goschler, Ádám;
Szarvas, Gábor;
Horváth, Klára;
Nagy, Simon Péter;
Prohászka, Zoltán;
Szilágyi, Ágnes;
Dobner, Sarolta

Publication type:

Article

Case Report: Hepatic sarcoidosis-like reaction from neoadjuvant pembrolizumab in early-stage triple-negative breast cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1589191

By:

Tan, Yujing;
Wang, Yu;
Liu, Xiaoyan;
Ma, Qin;
Zeng, Cheng;
Zhu, Aihua;
Sun, Xiaoying;
Ma, Fei;
Wang, Jiani

Publication type:

Article

Prostate cancer immunotherapy-based strategies: an updated review emphasizing immune checkpoint inhibitors.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1583363

By:

Lu, Hua;
Teng, Zhaojun;
Wang, Jiajia;
Zhang, Wenchao

Publication type:

Article

Landscape analysis of matrix metalloproteinases reveals key prognostic markers for prostate cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1582992

By:

Li, Wei;
Wei, Xi;
Yu, Ying;
Tian, Yuan;
Yu, Qi;
Qiao, Jun;
Tao, Yuewei;
Li, Yanfeng;
Li, Tao

Publication type:

Article

IL-24 producing regulatory T and B lymphocytes in endometriosis.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1582762

By:

Kedzierska, Anna Ewa;
Lorek, Daria;
Slawek, Anna;
Karmowski, Mikolaj;
Kalota, Aleksandra;
Pajak, Jaroslaw;
Chrobak, Agnieszka;
Grzymajlo, Krzysztof;
Chelmonska-Soyta, Anna

Publication type:

Article

Immunoglobulin Y antibodies against colonization-related genes block the growth and infection of Helicobacter pylori.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1582250

By:

Deng, Shiyuan;
Luo, Xiaoling;
Du, Yunxiao;
Elbaiomy, Rania G.;
He, Weihan;
Guo, Rong;
El-Sappah, Ahmed H.;
Jian, Xiaohong;
Xie, Yongmei;
Bakeer, Mohammed;
Li, Zaixin;
Zhang, Zhi

Publication type:

Article

Bibliometric and visual analysis of global crc circular RNA research 2015-2023.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1580405

By:

Bin, Jian Feng;
Chen, Long Fei;
Wang, Yan;
Ge, Hua;
Chen, Wei

Publication type:

Article

Colorectal cancer-infiltrating NK cell landscape analysis unravels tissue-resident PD-1<sup>+</sup> NK cells in microsatellite instability tumors.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1578444

By:

Obino, Valentina;
Giordano, Chiara;
Carlomagno, Simona;
Setti, Chiara;
Greppi, Marco;
Bozzo, Matteo;
Pesce, Silvia;
Ferretti, Elisa;
Candiani, Simona;
Muccio, Letizia;
Ciferri, Enrico;
Buttiron Webber, Tania;
Solari, Agnese;
Ortolani, Fulvia;
Paleari, Laura;
Clavarezza, Matteo;
Barberis, Andrea;
Filauro, Marco;
Provinciali, Nicoletta;
Rutigliani, Mariangela

Publication type:

Article

High NK cell counts at day 90 predict improved survival in event-free patients after T-cell depleted allogeneic stem cell transplantation.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1577924

By:

Pešić, Andrej;
Bešević, Nevena;
Kröger, Nicolaus;
Stanisavljević, Dejana;
Kraguljac Kurtović, Nada;
Bukumirić, Zoran;
Kecman, Natalija;
Lemajić, Nikola;
Smiljanić, Mihailo;
Suvajdžić Vuković, Nada;
Bogdanović, Andrija;
Vidović, Ana;
Bila, Jelena;
Mitrović, Mirjana;
Leković, Danijela;
Virijević, Marijana;
Đunić, Irena;
Antić, Darko;
Todorović Balint, Milena

Publication type:

Article

Evolving fitness and immune escape: a retrospective analysis of SARS-CoV-2 spike protein (2020-2024) using protein language model.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1576414

By:

Peng, Sihua;
Lyu, Leke;
Carmola, Ludy Registre;
Subedi, Sachin;
Mubassir, M. H. M.;
Bakheet, Mohamed A.;
Bahl, Justin

Publication type:

Article

Role of macrophages in neuroimmune regulation.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1573174

By:

Xiao, Hairong;
Yang, Kai

Publication type:

Article

In evolution's unending race: ancestral STING sensors in Salmo salar mediate intracellular bacterial detection and programmed cell death through evolutionarily conserved pathways.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1570871

By:

Yañez, Alejandro J.;
Beltrán, Jorge F.;
Barrientos, Claudia A.;
Soto-Rauch, Genaro;
Aguilar, Marcelo;
Isla, Adolfo;
Flores-Martin, Sandra N.;
Yañez, Francisco T.;
Yuivar, Yassef;
Ojeda, Adriana;
Almendras, Felipe;
Bustos, Patricio;
Mancilla, Marcos

Publication type:

Article