Works in Frontiers in Pharmacology, 2025

Results: 2239

Cost-analysis of universal decolonization with pure hypochlorous acid and mupirocin to reduce MRSA infections in intensive care burn unit patients.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1606589

By:

Mallow, Peter J.;
Chakravarthy, Debashish;
Foster, Kevin

Publication type:

Article

Correction: Andrographis paniculata restores gut health by suppressing inflammation and strengthening mucosal immunity.

Published in:

2025

By:

Tyagi, Vidushi;
Kumar, Ashish;
Shanker, Karuna;
Pal, Anirban

Publication type:

Correction Notice

Effects of previous steroid treatment on ischemic stroke outcomes: a propensity score-matched hospital analysis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1615170

By:

Alatawi, Yasser;
Alraddadi, Eman A.;
Alhifany, Abdullah A.;
Alzahrani, Faisal E.;
Alknawy, Saud M.;
Aljohani, Nawaf M.;
Kecheck, Husun K.;
Alaslab, Alanoud K.;
Alamri, Aser F.;
Aljabri, Ahmed;
Almarghalani, Daniyah A.;
Alamri, Faisal F.

Publication type:

Article

Tricin selectively combats KRAS-mutant non-small cell lung cancer by inhibiting the PDGF-BB-induced SRC/MAPK/AP-1/PD-L1 signaling pathway and potentiating the antitumor effect of an anti-PD-1 antibody.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1594213

By:

Li, Jia-Xin;
Tan, Shi-Yu;
Li, Li-Qi;
Zheng, Yu-Hong;
Zhao, Lin;
Zhu, Hui-Rong;
He, Hai-Lang;
Zhang, Yan-Yu;
Li, Run-Ze;
Bao, Tian-Yu;
Zhang, Yi-Zhong;
Yang, Xiao-Man;
Zhang, Hao;
Chen, Hui-Hui;
Wu, Bo-Wen;
Lin, Xin;
Lin, Xiao-Sheng;
Lin, Yin Cheng;
Sui, Xin-Bing;
Xie, Ying

Publication type:

Article

A comprehensive overview of triptolide utilizing nanotechnology and its potential applications in prostate diseases.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1592066

By:

Yan, Tongyin;
Wang, Yiao;
Hou, Zhiyan;
Song, Pan;
Wang, Puze;
Li, Jinze;
Zheng, Jing;
Lv, Dong

Publication type:

Article

Multiple myeloma inhibitory effects of natural compounds: enhancement through nanoparticle carriers.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1589090

By:

Wong, Erica;
Staskiewicz, Anna;
Pruner, Joshua;
Lee, Jean;
Tucker, Michael;
Smith, Barkley;
Rogers, Lanerica;
Asuni, Ganiat;
Wang, Xinyu

Publication type:

Article

Decoding the therapeutic mechanism of Conocarpus lancifolius in hepatocellular carcinoma: network pharmacology, molecular docking, and LC-MS QTOF insights.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1582374

By:

Prajapati, Poojaben M.;
Patel, Saumya K.;
Rawal, Rakesh M.;
Lakhani, Komal G.;
Hamid, Rasmieh;
Maitreya, Bharat B.

Publication type:

Article

Pharmacological potential of natural chalcones: a recent studies and future perspective.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1570385

By:

Adhikari, Suman;
Nath, Priyatosh;
Deb, Vishal Kumar;
Das, Niranjan;
Banerjee, Antara;
Pathak, Surajit;
Duttaroy, Asim K.

Publication type:

Article

Effects of anti-osteoporotic drugs in patients with chronic kidney disease: a systemic review and network meta-analysis of bone mineral density, clinical fracture rate and renal function.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1569744

By:

Wung, Chih-Hsuan;
Liu, Hao-Yu;
Tsai, Tsung-Ting;
Chen, Jia-Jin

Publication type:

Article

Naringenin attenuates slow-transit constipation by regulating the AMPK/mTOR/ULK1 signalling pathway: in vivo and in vitro studies.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1550458

By:

Wang, Yahui;
Wang, Xiaopeng;
Qian, Yifei;
Sun, Mingming;
Yang, Huiju;
Su, Lianlin;
Yan, Shuai

Publication type:

Article

Targeting tumor-associated macrophages in gastric cancer progression and therapy: insights from molecular mechanisms to therapeutic applications.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1549694

By:

Wan, ChengTao;
Deng, Jie;
Zhu, Yu;
Wan, Li;
Xu, Linyue;
Chen, Qiuyan;
Zou, Can;
Huang, Ju

Publication type:

Article

Calcio-herbal medicine Divya-Swasari-Vati demonstrates acceptable non-clinical safety profile in the repeated-dose 28-day subacute oral toxicity study in Sprague-Dawley rats, under GLP compliance.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1547532

By:

Balkrishna, Acharya;
Sinha, Sandeep;
Varshney, Anurag

Publication type:

Article

Pulmonary delivery of excipient-free tobramycin DPIs for the treatment of Pseudomonas aeruginosa lung infection with CF.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1528905

By:

Cheng, Song;
Huang, Haozhou;
Zhang, Zhihao;
Chen, Mateng;
Zhang, Yulong;
Lin, Mengxing;
Yang, Gang;
Kanye, Lynda Thubelihle;
Zhang, Qingzhen;
Xue, Ning;
Shi, Kaiqi;
Dong, Bin;
Li, Hanhan

Publication type:

Article

Correction: Ginsenoside compound K attenuates Ox-LDL-mediated macrophage inflammation and foam cell formation via autophagy induction and modulating NF-κB, p38, and JNK MAPK signaling.

Published in:

2025

By:

Lu, Shan;
Luo, Yun;
Sun, GuiBo;
Sun, XiaoBo

Publication type:

Correction Notice

Ginsenoside Compound K Attenuates Ox-LDL-Mediated Macrophage Inflammation and Foam Cell Formation via Autophagy Induction and Modulating NF-κB, p38, and JNK MAPK Signaling.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2020.567238

By:

Lu, Shan;
Luo, Yun;
Sun, GuiBo;
Sun, XiaoBo

Publication type:

Article

Correction: Polygoni Multiflori Radix Praeparata polysaccharides enhance gut health and mitigate ischemic stroke by regulating SCFA and amino acid metabolism in gut microbiota.

Published in:

2025

By:

Ruan, Lingyu;
Wang, Zhennan;
Zheng, Mengyun;
Zheng, Qi;
Qing, Qing;
Lin, Hongyan;
Tao, Yuheng;
Wang, Liqun;
Wang, Junsong;
Ge, Wenhao

Publication type:

Correction Notice

Correction: Biomineralized composite liquid crystal fiber scaffold promotes bone regeneration by enhancement of osteogenesis and angiogenesis.

Published in:

2025

By:

Zhan, Yi;
Deng, Bing;
Wu, Huixian;
Xu, Changpeng;
Wang, Ruiying;
Li, Wenqiang;
Pan, Zhixiong

Publication type:

Correction Notice

Polygoni Multiflori Radix Praeparata polysaccharides enhance gut health and mitigate ischemic stroke by regulating SCFA and amino acid metabolism in gut microbiota.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1580055

By:

Ruan, Lingyu;
Wang, Zhennan;
Zheng, Mengyun;
Zheng, Qi;
Qing, Qing;
Lin, Hongyan;
Tao, Yuheng;
Wang, Liqun;
Wang, Junsong;
Ge, Wenhao

Publication type:

Article

Andrographis paniculata restores gut health by suppressing inflammation and strengthening mucosal immunity.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1536683

By:

Tyagi, Vidushi;
Kumar, Ashish;
Shanker, Karuna;
Pal, Anirban

Publication type:

Article

Ginsenosides Rh2 and Rg3 exert their anti-cancer effects on non-small cell lung cancer by regulating cell autophagy and choline-phosphatidylcholine metabolism.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1507990

By:

Min, Zhao;
Er-Xi, Che;
Lin-Juan, Wang;
Lin, Wang;
Bi-Li, Liu;
Qiu-Fang, Chen

Publication type:

Article

Biomineralized Composite Liquid Crystal Fiber Scaffold Promotes Bone Regeneration by Enhancement of Osteogenesis and Angiogenesis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2021.736301

By:

Zhan, Yi;
Deng, Bing;
Wu, Huixian;
Xu, Changpeng;
Wang, Ruiying;
Li, Wenqiang;
Pan, Zhixiong

Publication type:

Article

Editorial: Multi-target drug discovery and design for complex health disorders.

Published in:

2025

By:

Badria, Farid A.;
De Filippis, Barbara;
El-Magd, Mohammed Abu;
Elbadawi, Mostafa M.;
Hamdi, Abdelrahman;
Elgazar, Abdullah A.

Publication type:

Editorial

Salt sensitivity and myocardial fibrosis: unraveling the silent cardiovascular remodeling.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1626492

By:

Mutengo, Katongo Hope;
Ngalamika, Owen;
Kirabo, Annet;
Masenga, Sepiso K.

Publication type:

Article

Guarding minds: a narrative review on how n-acetylcyteine and ketones could shield sensitive patients from antibiotic neurotoxicity.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1613152

By:

Lounici, Astrid

Publication type:

Article

Reversal of ABCG2-mediated drug resistance by tinodasertib (ETC-206).

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1606857

By:

Yang, Haigan;
Li, Zheshen;
Wu, Zhuoxun;
Chen, Xiang;
Bo, Letao;
Patel, Harsh;
Zhang, Bohan;
Xiong, Wenjun;
Wang, Wei;
Chen, Zhe-Sheng

Publication type:

Article

Molecular mechanisms of polychlorinated biphenyls in breast cancer: insights from network toxicology and molecular docking approaches.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1604993

By:

Yang, Xiaoyu;
Liang, Wenlong;
Feng, Zhenchu;
Li, Guangyan;
Chen, Xi;
Zhang, Jianguo

Publication type:

Article

Adu CPI2 alleviates MSU-induced acute gouty arthritis in mice by inhibiting cathepsin S and the C5a-C5aR1 axis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1604329

By:

Liu, Sijing;
Situ, Yongli;
Deng, Li;
Liang, Meng;
He, Haoyuan;
Shao, Zheng;
Peng, Lifei

Publication type:

Article

Advances and challenges in cancer immunotherapy: mechanisms, clinical applications, and future directions.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1602529

By:

Vatsavai, Neeharika;
Kaur Bhinder, Sumeet;
Shaik, Rahaman;
Mahira, Shaheen;
Kapoor, Shruti;
Ali, Md Shadab;
Verma, Deepak;
Singh, Jay;
Badavenkatappa Gari, Sreelakshmi;
Upadhyay, Prabhat;
Meshkovska, Yeva;
Godugu, Chandraiah;
Thatikonda, Sowjanya;
Pooladanda, Venkatesh

Publication type:

Article

Efficacy and safety of Rhodiola crenulata extract in the treatment of acute high altitude disease, based on studies involving populations in China: A systematic review and meta-analysis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1595953

By:

Gao, Zixuan;
Liu, Yaoyuan;
Liao, Weiwen;
Song, Wenting;
Zhang, Xinyi;
Lin, Hanqing;
Zhang, Han;
Zhang, Tao;
Pang, Wentai

Publication type:

Article

Editorial: Mobilization of hematopoietic cells from the bone marrow to the peripheral blood: Challenges and new therapeutic targets.

Published in:

2025

By:

Szade, Agata;
Gulati, Gunsagar S.;
Czechowicz, Agnieszka D.

Publication type:

Editorial

Integrating Drosophila and Vibrio fischeri models for toxicity evaluation: uncovering detoxification trends in psoralea Fructus-TCM formulations.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1590929

By:

Zhang, Cheng;
Li, Yina;
Li, Fangyang;
Dang, Wanyun;
Shi, Zhuo;
Yang, Chunqi;
Xiao, Chengrong;
Tang, Xianglin;
Wang, Yuguang;
Gao, Yue

Publication type:

Article

Lactate-induced lactylation: from basic research to clinical perspectives.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1586973

By:

Shi, Henghe;
Zou, Yifei;
Jin, Sijie;
Wu, Junduo;
Liu, Bin

Publication type:

Article

Autophagy inhibition induced by EM-2 augments apoptosis via ROS-mediated ATM-Chk2-p53-p21 and MAPK pathway in lung and breast carcinoma.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1580217

By:

Cheng, Jinxia;
Chen, Ying;
Chen, Qi;
Cao, Ning;
He, Chuyu;
Xu, Yanjun;
Zhang, Xiaoying;
Li, Qiang;
Hong, Hong;
Jiang, Jianwei;
Wang, Yuechun

Publication type:

Article

Therapeutic drug monitoring of voriconazole and the impact of inflammation on plasma trough concentrations in children.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1575233

By:

Hu, Lin;
Wang, Changyu;
Tang, Xi;
Huang, Qi;
Li, Yanfei;
Huang, Shiqiong

Publication type:

Article

Identification of an Ara-C resistance-related gene risk score and the role of S100A4 in AML via NR6A1-dependent activation and p53 regulation.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1574759

By:

Wang, Li;
Huang, Aoshuang;
Cheng, Bingqing;
Hu, Xiuying;
Wang, Jishi

Publication type:

Article

Mechanistic Insights and Anti-cancer Activity of 2H-benzo[b][1,4]oxazin-3(4H)-one Linked 1,2,3-Triazoles in Human Cancer Cells.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1565657

By:

Liu, Qingying;
Hou, Xixi;
Tian, Mingyue;
He, Baoyu;
Guo, Jingjing;
Guo, Yajie;
Yang, Jianxue

Publication type:

Article

Hsa_circ_0002238 promotes the malignant behavior of colorectal cancer.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1541820

By:

Zhang, Lin-Ting;
Zhou, Yuejia;
Wang, Tiantian;
Chen, Boran;
Cai, Zhigao;
Wang, Shubin;
Tong, Gangling

Publication type:

Article

Efficacy of Xiaoyao-san preparations in treating Hashimoto's thyroiditis: a meta-analysis and systematic review.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1528506

By:

Wang, Chengna;
Ma, Wenxin;
Qin, Lingling;
Wu, Lili;
Liu, Tonghua

Publication type:

Article

Clinical features and genetic spectrum of children with primary ciliary dyskinesia in central China: a referral center retrospective analysis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1526675

By:

Zhang, Xiaoning;
Jin, Xiuhong;
Zhang, Zhiying;
Wang, Yanqiong;
Zhang, Xiangfeng;
Dong, Zhen;
Yang, Haiming;
Shen, Yuelin

Publication type:

Article

The anti-depressive role of the Pei Yuan Kai Yu formula in cerebral small vessel disease based on gut microbiota.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1510250

By:

Yang, Lixuan;
Ao, Yutian;
Li, Yannan;
Dai, Baoan;
Li, Junnan;
Duan, Wenzhe;
Dong, Kaiqiang;
Han, Zhenyun;
Guo, Rongjuan

Publication type:

Article

Efficacy and safety of Danhong injection on inflammatory factors and vascular endothelial function in patients with unstable angina pectoris: a systematic review and meta-analysis of randomized clinical trials.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1389746

By:

Kan, Zunqi;
Yan, Wenli;
Chen, Cong;
Gao, Huanyu;
Song, Yongmei

Publication type:

Article

Retraction: Polyphenolic fraction obtained from Thalassia testudinum marine plant and thalassiolin B exert cytotoxic effects in colorectal cancer cells and arrest tumor progression in a xenograft mouse model.

Published in:: 2025
Publication type:: Correction Notice

Investigation on current situation of Chinese patent medicines for children in China based on the national drug coding database.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1626274

By:

Liu, Hui;
Rong, Ping;
Zhang, Yatong;
You, Yuqiong;
Fu, Qianfang;
Cai, Lili;
Wei, Juan;
Ma, Rong

Publication type:

Article

Unexpected voriconazole toxicity due to nirmatrelvir/ritonavir: a case report on drug-drug interaction and the role of therapeutic drug monitoring.

Published in:

2025

By:

López-Hernández, J.;
Guisado-Gil, A. B.;
Mejías-Trueba, M.;
Herrera-Hidalgo, L.;
Reina-Martínez, F. J.;
Gil-Navarro, M. V.

Publication type:

Case Study

Engineered immune cell therapies for solid tumors: pharmacological advances, clinical outcomes, and future directions.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1614325

By:

Althafar, Ziyad M.

Publication type:

Article

Efficacy of danhong injection adjuvant therapy in patients with acute ischemic stroke: a real-world, multicenter, retrospective study.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1608719

By:

Pan, Danping;
Wan, Haitong;
He, Yu;
Yang, Jiehong;
Guo, Yilei;
Yu, Li;
Zhang, Feihu;
Zheng, Guoqing;
Xu, Bin;
Song, Yaohong;
Zhao, Mingjun;
Liu, Xiangzhe;
Liu, Jianhe;
Sun, Gang;
Lin, Yaming

Publication type:

Article

Corrigendum: A telomere-related signature for predicting prognosis and assessing immune microenvironment in osteosarcoma.

Published in:

2025

By:

Li, Shihao;
Zhang, Lina;
Zhang, Haiyang

Publication type:

Correction Notice

Mechanistic insights into the PAI-1 inhibitor PAItrap3: enhancing lipid metabolism in adipose tissue of diabetic db/db mice.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1596655

By:

Wang, Linxi;
Zhang, Zhouyangyang;
Lin, Menghua;
Qi, Liqin;
Liu, Libin;
Chen, Zhuo;
Tang, Shuzhi;
Wang, Lijing

Publication type:

Article

Polygala tenuifolia Willd. Extract delays non-alcoholic fatty liver disease progression in rats via the COX2 and PERK-elF2α-ATF4 pathway.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1595752

By:

Sun, Zhiliang;
Zhou, Zhongshi;
Liao, Kezheng;
Liu, Yanju;
Liu, Yanyun;
Wang, Chaoyang;
Zhang, Zhihua;
Wen, Li

Publication type:

Article

The flexibility of SABRE, a new quantitative receptor function model, when fitting challenging concentration-effect data.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1591761

By:

Olah, Barbara;
Tarjanyi, Vera;
Takacs, Barbara;
Pluzsnyik, Edua;
Viczjan, Gabor;
Ovari, Ignac;
Szilvassy, Zoltan;
Juhasz, Bela;
Zsuga, Judit;
Erdei, Tamas;
Gesztelyi, Rudolf

Publication type:

Article