Works in Clinical & Experimental Medicine, 2025, Vol 25, Issue 1

Results: 207

SPOP-dependent destabilization of SYT12 in a GSK-3β-dependent manner in papillary thyroid cancer cells.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01791-z

By:

Zhou, Shaocheng;
Du, Qidan;
Xu, Limei;
Kang, Xiaohong

Publication type:

Article

Ropeginterferon alfa-2b as a promising alternative to conventional interferon in CDA type 1: a case report of two siblings.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01785-x

By:

Yang, Tyng-Wei;
Tsai, Xavier Cheng-Hong;
Fu, Yu-Hsuan;
Lin, Liang-In;
Hou, Hsin-An

Publication type:

Article

The AML immune paradox: decoding escape pathways and pioneering checkpoint, vaccine, and combination strategies.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01795-9

By:

Soleimani Samarkhazan, Hamed;
Shafiei, Fatemeh Sadat;
Taghinejad, Zahra;
Maleknia, Mohsen;
Noormohamadi, Hanieh;
Raoufi, Atieh;
Nouri, Sina

Publication type:

Article

The efficacy and safety of venetoclax combined with decitabine in elderly patients with acute myeloid leukemia: a systematic review and meta-analysis.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01794-w

By:

He, Feng;
Tian, Tian;
Qiao, Shukai;
Xing, Lina

Publication type:

Article

CCL22 as a diagnostic and prognostic biomarker for pediatric-onset systemic lupus erythematosus.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01790-0

By:

Chen, Xiao-lin;
Liu, Chen-xi;
Huang, Meng-ke;
Hui, Lu;
Liu, Ting;
Jiang, Yong-mei

Publication type:

Article

Predicting SARS-CoV-2-specific CD4<sup>+</sup> and CD8<sup>+</sup> T-cell responses elicited by inactivated vaccines in healthy adults using machine learning models.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01772-2

By:

Ning, Jie;
Ren, Yayi;
Zhang, Zelin;
Zeng, Xianhuang;
Wang, Qinjin;
Xie, Jia;
Xu, Yue;
Fan, Yali;
Li, Huilan;
Zhai, Aixia;
Li, Bin;
Wu, Chao;
Chen, Ying

Publication type:

Article

Applications of CRISPR-Cas9 in mitigating cellular senescence and age-related disease progression.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01771-3

By:

Azani, Alireza;
Sharafi, Malihe;
Doachi, Reyhaneh;
Akbarzadeh, Sama;
Lorestani, Parsa;
Haji Kamanaj Olia, Arash;
Zahed, Zahra;
Gharedaghi, Hossein;
Ghasrsaz, Haniyeh;
Foroozand, Hassan;
Rahimi, Hossein;
Tahmasebi, Safa;
Behfar, Qumars

Publication type:

Article

Rationale of using immune checkpoint inhibitors (ICIs) and anti-angiogenic agents in cancer treatment from a molecular perspective.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01751-7

By:

Sherafat, Negar Sadat;
Keshavarz, Ali;
Mardi, Amirhossein;
Mohammadiara, Amirmohammad;
Aghaei, Mojtaba;
Aghebati-Maleki, Leili;
Mohammadi, Mohammad Hossein

Publication type:

Article

MicroRNAs at the crossroads of exercise and ferroptosis: a regulatory bridge.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01766-0

By:

Lin, Zhao;
Feng, Zhang

Publication type:

Article

Potential therapeutic roles of natural killer cells in acute myeloid leukemia: a systematic review study.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01786-w

By:

Khani-Eshratabadi, Mohammad;
Motallebzadeh Khanmiri, Jamal;
Dashti, Mohammad Reza;
Esmaeili, Sina;
Moradi Sani, Zeinab;
Daei, Amirreza;
Hedayat Hasanabadi, Mohaddeseh;
Saberi Amarghan, Simin;
Younesi Moghaddam, Nazanin;
Baradaran, Behzad

Publication type:

Article

Analysis of prognostic factors affecting TA-TMA patients: a single-center retrospective study.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01774-0

By:

Liu, Jile;
Meng, Haotian;
Zhang, Tao;
Liu, Xiu;
Zhao, Mingfeng

Publication type:

Article

Antitumor effects of human antithymocyte globulin on peripheral T cell lymphoma via complement-dependent and -independent cytotoxicity in xenograft mouse models.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01726-8

By:

Gao, Bei-Bei;
Zhang, Tian-Qi;
Zhang, Jing-Jing;
Wang, Hai-Na;
Huang, Dan;
Zhang, Xue-Hong;
Kang, Zhi-Jie;
Yang, Yan;
Liu, Xiao-Lan;
Sun, Chuang;
Shao, Jing;
Yan, Jin-Song

Publication type:

Article

The epigenetic revolution in hematology: from benchside breakthroughs to clinical transformations.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01783-z

By:

Abdar Esfahani, Mahdis;
Servatian, Nazli;
Al-Athari, Ali Jihad Hemid;
Khafaja, Elaf Salah Mehdi;
Rahmani Seraji, Hamideh;
Soleimani Samarkhazan, Hamed

Publication type:

Article

Dynamics of serum tumor markers may indicate the progression of interstitial lung disease in Sjögren's syndrome patients: new roles for old friends.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01779-9

By:

Song, Jiamin;
Gao, Ronglin;
Han, Fang;
Pu, Jincheng;
Liang, Yuanyuan;
Wang, Yanqing;
Wu, Zhenzhen;
Pan, Shengnan;
Wu, Huihong;
Sun, Yuhang;
Lin, Kailong;
Tang, Jianping;
Wang, Xuan

Publication type:

Article

Preoperative ctDNA retains prognostic relevance beyond postoperative assessment in stage II–III colon cancer.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01762-4

By:

Chisari, Giulia;
Martorana, Emanuele;
Lombardo, Sofia Paola;
Raciti, Gabriele;
Giuffrida, Raffaella;
Bardelli, Alberto;
Scionti, Domenico;
Mare, Marzia;
Picardo, Carolina;
Deiana, Enrica;
Memeo, Lorenzo;
Colarossi, Cristina;
Crisafulli, Giovanni;
Forte, Stefano

Publication type:

Article

Functional remodeling of tissue-resident macrophages leads to distinct immune microenvironment evolution and clinical manifestations in lung adenocarcinoma.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01760-6

By:

Li, Yanqi;
Jiang, Li;
Liu, Xiaobing;
Dai, Jigang;
Liu, Quanxing

Publication type:

Article

Integrative regression modeling of insulin sensitivity, resistance, and beta-cell dysfunction in predicting female infertility: a cross-sectional NHANES study.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01755-3

By:

Bahreiny, Seyed Sobhan;
Khaksar, Mohammad Ali;
Karamali, Negin;
Dabbagh, Mohammad Reza;
Hoseinnejad, Akbar;
Mohammadpour Fard, Reza;
Bahreiny, Zahra Sadat;
Aghaei, Mojtaba;
Sakhavarz, Tannaz;
Zahedian, Mehdi

Publication type:

Article

Integrated analysis of CD30 detection methodologies and synergistic drug combinations for optimizing brentuximab vedotin therapy in lymphoma.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01765-1

By:

Ye, Mingyu;
Wang, Tao;
Song, Zhiqiang;
Liu, Xuefei;
Liu, Ping;
Zhang, Ling;
Tang, Gusheng;
He, Miaoxia;
Liu, Na;
Yang, Jianmin

Publication type:

Article

YY1-mediated DUXAP8 facilitates HCC progression via modulating DEPDC1 expression.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01572-8

By:

Cui, Yi;
Sun, Yong;
Liang, Na;
Tian, Chuan

Publication type:

Article

Differential response of patient-derived primary glioblastoma cells to metabolic and adhesion inhibitors.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01736-6

By:

Rezk, Rasha;
Basar, Fikret;
Mediavillo, John;
Donaldson, Rebecca;
Watts, Colin;
Franze, Kristian;
Kabla, Alexandre J.

Publication type:

Article

Angioimmunoblastic T-cell lymphoma: a concise overview encompassing the pathogenetic, pathological, clinical, therapeutical characteristics, and recent advances.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01754-4

By:

Feng, Yan;
Ma, Yaxian;
Li, Tongjuan;
Liu, Min;
Hong, Zetong;
Yin, Qing;
Zheng, Miao

Publication type:

Article

Risk of new or recurrent cancer during treatment with biologics in patients with immune-mediated inflammatory diseases and previous cancer: a meta-analysis.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01738-4

By:

Isufi, Daniel;
Schwarz, Christopher Willy;
Jensen, Mikkel Bak;
Seidelin, Jakob;
Skov, Lone;
Loft, Nikolai

Publication type:

Article

Targeting acute myeloid leukemia through antibody engineering: innovations in immunotherapy and combination regimens.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01764-2

By:

Soleimani Samarkhazan, Hamed;
Noormohamadi, Hanieh;
Shafiei, Fatemeh Sadat;
Taghinejad, Zahra;
Maleknia, Mohsen;
Raoufi, Atieh;
Nouri, Sina;
Mohammadi, Mohammad Hossein

Publication type:

Article

Performance analysis of large language models Chatgpt-4o, OpenAI O1, and OpenAI O3 mini in clinical treatment of pneumonia: a comparative study.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01743-7

By:

Lin, Zhiwu;
Li, Yuanyuan;
Wu, Min;
Liu, Hongmei;
Song, Xiaoyang;
Yu, Qian;
Xiao, Guibao;
Xie, Jiajun

Publication type:

Article

Global and regional prevalence of osteoporosis in kidney transplant recipients: a systematic review and meta-analysis.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01716-w

By:

Ghazaiean, Mobin;
Mousavi, Tahoora;
Moosazadeh, Mahmood

Publication type:

Article

Innovative technologies and their clinical prospects for early lung cancer screening.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01752-6

By:

Deng, Zisu;
Ma, Xiaocao;
Zou, Shubiao;
Tan, Liling;
Miao, Tingting

Publication type:

Article

Differential risk factors of fibrosis between lean and obese MAFLD.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01749-1

By:

Mostafa, Alaa M.;
Fouad, Yasser;
Gaber, Yasmine;
Alem, Shereen Abdel;
Pan, Ziyan;
Eslam, Mohammed

Publication type:

Article

Regulation of pyroptosis in diabetic nephropathy by long non-coding and circular RNAs.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01740-w

By:

Hushmandi, Kiavash;
Klionsky, Daniel J.;
Farahani, Najma;
Reiter, Russel J.;
Imani Fooladi, Abbas Ali Imani;
Alimohammadi, Mina;
Aref, Amir Reza

Publication type:

Article

The application performance of MRI-PDFF detection values of different hepatic lobes in diagnosing liver steatosis.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01739-3

By:

Qiao, Fengjie;
Xue, Yan;
Zou, Chen;
Liu, Kun;
Yuan, Jie;
Ji, Longshan;
Huang, Lingying;
Li, Man;
Gao, Yueqiu

Publication type:

Article

Evaluation and verification of MPDZ as a prognostic biomarker for hepatocellular carcinoma through multiple databases.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01729-5

By:

Luo, Jianzhu;
Liang, Jianhua;
Xie, Haixiang;
Chen, Jiaguang;
Shen, Xiaoqiang;
Yang, Fuquan;
Li, Tianman

Publication type:

Article

Clinicopathological features and renal outcomes in patients with IgA nephropathy secondary to psoriasis.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01750-8

By:

He, Dafeng;
Bi, Guangyu;
Mou, Hongbin;
Wang, Rong;
Lu, Chunlei;
Tang, Zheng

Publication type:

Article

β-catenin as a key regulator of the cisplatin response in tumor cells.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01757-1

By:

Saburi, Ehsan;
Moghbeli, Meysam

Publication type:

Article

AI-driven techniques for detection and mitigation of SARS-CoV-2 spread: a review, taxonomy, and trends.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01753-5

By:

Ghorbian, Mohsen;
Ghorbian, Saied;
Ghobaei-Arani, Mostafa

Publication type:

Article

HNF4A promotes tumor progression in gastric cancer by transcriptional activation of KIF2C.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01748-2

By:

Lu, Hao;
Gan, Jin-heng;
Zhou, Li-qiang;
Yuan, Yi-Wu;
Zhou, Qi;
Xin, Lin

Publication type:

Article

Impact of age on frailty in liver cirrhosis: a prospective cohort study.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01747-3

By:

Alhaddad, Omkolsoum;
Elsabaawy, Maha;
Abedelhai, Asmaa;
Badra, Gamal;
Elfayoumy, Marwa

Publication type:

Article

Predictive and prognostic value of the neutrophil-to-lymphocyte ratio for acute kidney injury: a systematic review and meta-analysis.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01746-4

By:

Wei, Wei;
Yang, Binyu;
Zhu, Yuyi;
Liu, Caihong;
Huang, Yongxiu;
Yang, Letian;
Li, Jian;
Ren, Jinglei;
Ma, Liang;
Zhang, Ling;
Zhao, Yuliang;
Fu, Ping

Publication type:

Article

Prognostic impact of somatic mutations and additional chromosomal abnormalities in patients with myelodysplastic syndromes and chromosome 20q deletion.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01742-8

By:

Huang, Xinhui;
Li, Xiao;
Liu, Qi;
Guo, Juan;
Chen, Jianan;
Zhou, Liyu;
Song, Luxi;
Zhang, Zheng;
Su, Jiying;
Zhang, Yumei;
Yan, Meng;
He, Qi;
Wu, Dong;
Xu, Feng;
Chang, Chunkang;
Wu, Lingyun

Publication type:

Article

Exploring the molecular mechanisms of lactylation-related biological functions and immune regulation in sepsis-associated acute kidney injury.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01745-5

By:

Jiang, Kui;
Mai, Shujuan;
Li, Jian;
Zhou, Hongxing;
Chen, Yu;
Zou, Leyuan;
Yu, Huixia

Publication type:

Article

28-day all-cause mortality in patients with alcoholic cirrhosis: a machine learning prediction model based on the MIMIC-IV.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01744-6

By:

Lei, Chuang;
Ding, Zhixiang;
Wang, Qinghai;
Tao, Shanqing;
Zhou, Qin;
Yin, Pengfei;
Luo, Yanhong;
Yang, Fan;
Chen, Xingtong;
Cai, Yang;
Gong, Hainan;
Li, Dehui;
Li, Hao

Publication type:

Article

CCAT2 role in gastrointestinal cancer progression and metastasis: a novel target for therapeutic strategies.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01730-y

By:

Vanan, Ahmad Ghorbani;
Ghorbaninezhad, Farid;
Nikeghbali, Golnaz;
Mohamadi, Fateme;
Ayati, Ariyan;
Mastani, Reza Ghanbari;
Shahhoseini, Zahra;
Eini, Pooya;
Ahmadi, Ronak;
Tahmasebi, Safa;
Safarzadeh, Elham

Publication type:

Article

Correction: Identification of a metabolic-immune signature associated with prognosis in colon cancer and exploration of potential predictive efficacy of immunotherapy response.

Published in:

2025

By:

Xie, Yuwen;
Guan, Shenyuan;
Li, Zhenkang;
Cai, Guohao;
Liu, Yuechen;
Li, Guoxin;
Huang, Ping;
Lin, Mingdao

Publication type:

Correction Notice

Donepezil for cancer-related cognitive impairment: systematic review and meta-analysis.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01708-w

By:

Fornalik, Michał;
Moska, Sandra;
Gimła, Mariola;
Yabluchanskiy, Andriy;
Bonin Pinto, Camila

Publication type:

Article

Development and validation of a nomogram risk prediction model for PICC-related thrombosis in children with hematological malignancies.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01707-x

By:

Fu, Maoling;
Yang, Qiaoyue;
Wu, Xiao;
Li, Xinyu;
Jiang, Lexue;
Yan, Huiping;
Yu, Genzhen

Publication type:

Article

Elevated eosinophil-to-lymphocyte ratio (ELR) as a predictor of relapse for IgG4-related disease: a retrospective study across a decade.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01741-9

By:

Zhang, Nianyi;
Peng, Yu;
Li, Rongli;
Nie, Yuxue;
Li, Jingna;
Yang, Xinli;
Zhang, Jialei;
Wang, Yifei;
Luo, Qinhuan;
Zhou, Jiaxin;
Fei, Yunyun;
Li, Mengtao;
Peng, Linyi;
Zhang, Wen

Publication type:

Article

The role of IL-17-related signaling in myelomagenesis, disease prognosis/progression, and therapeutic approach—a scoping review.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01728-6

By:

Kulig, Piotr;
Rałowiec, Anna;
Baumert, Bartłomiej;
Machaliński, Bogusław

Publication type:

Article

A study on the factors influencing mortality risk in sepsis-induced acute kidney injury based on analysis of the MIMIC database.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01681-4

By:

Ye, Chongyang;
Zhu, Chunyan;
Hu, Shijing;
Mei, Yulin;
Yang, Tianjun

Publication type:

Article

CXCL12 expression and the survival of patients with gastric cancer: a meta-analysis.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01674-3

By:

Wen, Jinxiu;
Zheng, Bingbing;
Fu, Ting

Publication type:

Article

CD44-downregulation in multiple myeloma inhibits cytoskeleton rearrangement through actin depolymerization.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01649-4

By:

Wang, Zhenkui;
Guo, Yutong;
Yang, Chun;
Liang, Hongyan;
Zhou, Jie;
Huang, Lei;
Xu, Yan;
Xue, Li

Publication type:

Article

From myth to bedside: a scoping review of the applications of the chimeric antigen receptor in rheumatology.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01717-9

By:

Niño-Torres, Diego;
Quintana-López, Gerardo;
Salguero, Gustavo

Publication type:

Article

The reciprocal regulation between autophagy and IL-22: implications for immunity and therapy.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01695-y

By:

Yu, Yang;
Qiao, Mingbiao;
Liu, Jinbo;
Guo, Yuanbiao;
Sun, Yueshan

Publication type:

Article