Works about UNCOUPLING proteins

Results: 679

Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic β Cells.

Published in:

PLoS Biology, 2005, v. 3, n. 12, p. 1, doi. 10.1371/journal.pbio.0040031

By:

Bordone, Laura;
Motta, Maria Carla;
Picard, Frederic;
Robinson, Ashley;
Jhala, Ulupi S;
Apfeld, Javier;
McDonagh, Thomas;
Lemieux, Madeleine;
McBurney, Michael;
Szilvasi, Akos;
Easlon, Erin J;
Lin, Su-Ju;
Guarente, Leonard

Publication type:

Article

The UCP2 -866 G>A promoter region polymorphism is associated with nonalcoholic steatohepatitis.

Published in:

Liver International, 2015, v. 35, n. 5, p. 1574, doi. 10.1111/liv.12707

By:

Fares, Roberta;
Petta, Salvatore;
Lombardi, Rosa;
Grimaudo, Stefania;
Dongiovanni, Paola;
Pipitone, Rosaria;
Rametta, Raffaela;
Fracanzani, Anna Ludovica;
Mozzi, Enrico;
Craxì, Antonio;
Fargion, Silvia;
Sesti, Giorgio;
Valenti, Luca

Publication type:

Article

AAV-ie-mediated UCP2 overexpression accelerates inner hair cell loss during aging in vivo.

Published in:

Molecular Medicine, 2022, v. 28, p. 1, doi. 10.1186/s10020-022-00552-y

By:

Zhao, Chunli;
Yang, Zijing;
Chen, Zhongrui;
Liang, Wenqi;
Gong, Shusheng;
Du, Zhengde

Publication type:

Article

Phenotypic plasticity to chronic cold exposure in two species of Peromyscus from different environments.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2022, v. 192, n. 2, p. 335, doi. 10.1007/s00360-021-01423-4

By:

Hayward, Leah;
Robertson, Cayleih E.;
McClelland, Grant B.

Publication type:

Article

Pros and cons for the evidence of adaptive non-shivering thermogenesis in marsupials.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2021, v. 191, n. 6, p. 1085, doi. 10.1007/s00360-021-01362-0

By:

Jastroch, Martin;
Polymeropoulos, Elias T.;
Gaudry, Michael J.

Publication type:

Article

Browning of subcutaneous fat and higher surface temperature in response to phenotype selection for advanced endurance exercise performance in male DUhTP mice.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2017, v. 187, n. 2, p. 361, doi. 10.1007/s00360-016-1036-7

By:

Brenmoehl, J.;
Ohde, D.;
Albrecht, E.;
Walz, C.;
Tuchscherer, A.;
Hoeflich, A.

Publication type:

Article

Brown adipose tissue: physiological function and evolutionary significance.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2015, v. 185, n. 6, p. 587, doi. 10.1007/s00360-015-0907-7

By:

Oelkrug, R.;
Polymeropoulos, E.;
Jastroch, M.

Publication type:

Article

Absence of adaptive nonshivering thermogenesis in a marsupial, the fat-tailed dunnart ( Sminthopsis crassicaudata).

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2012, v. 182, n. 3, p. 393, doi. 10.1007/s00360-011-0623-x

By:

Polymeropoulos, E.;
Jastroch, M.;
Frappell, P.

Publication type:

Article

Identification of a distal enhancer of Ucp1 essential for thermogenesis and mitochondrial function in brown fat.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07468-3

By:

Su, Duo;
Jiang, Tingting;
Song, Yulong;
Li, Die;
Zhan, Siyuan;
Zhong, Tao;
Guo, Jiazhong;
Li, Li;
Zhang, Hongping;
Wang, Linjie

Publication type:

Article

Protein kinase 2 of the giant sarcomeric protein UNC-89 regulates mitochondrial morphology and function.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07042-3

By:

Matsunaga, Yohei;
Qadota, Hiroshi;
Ghazal, Nasab;
Lesanpezeshki, Leila;
Dorendorf, Till;
Moody, Jasmine C.;
Ahier, Arnaud;
Matheny, Courtney J.;
Vanapalli, Siva A.;
Zuryn, Steven;
Mayans, Olga;
Kwong, Jennifer Q.;
Benian, Guy M.

Publication type:

Article

Degrading an enzyme to increase its product: a novel approach to decoupling biosynthesis and growth.

Published in:

Synthetic Biology (23977000), 2019, v. 4, n. 1, p. N.PAG, doi. 10.1093/synbio/ysz001

By:

Kelly, Ciarán L

Publication type:

Article

Differential effects of heat stress on oxidative status of skeletal muscle with different muscle fibre compositions in broiler chicken.

Published in:

Journal of Animal & Feed Sciences, 2019, v. 28, n. 1, p. 78, doi. 10.22358/jafs/102830/2019

By:

Kikusato, M.;
Toyomizu, M.

Publication type:

Article

Effect of single nucleotide polymorphisms in the UCP3 and FOXO1 genes on carcass quality traits in Qinchuan cattle.

Published in:

Journal of Animal & Feed Sciences, 2018, v. 27, n. 4, p. 301, doi. 10.22358/jafs/97366/2018

By:

Gui, L. S.;
Jia, J. L.

Publication type:

Article

Fluorescent Light Energy (FLE) Acts on Mitochondrial Physiology Improving Wound Healing.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 2, p. 559, doi. 10.3390/jcm9020559

By:

Ferroni, Letizia;
Zago, Michela;
Patergnani, Simone;
Campbell, Shannon E.;
Hébert, Lise;
Nielsen, Michael;
Scarpa, Carlotta;
Bassetto, Franco;
Pinton, Paolo;
Zavan, Barbara

Publication type:

Article

Effects of uncoupling protein 2 on prognosis and immune microenvironment of skin cutaneous melanoma.

Published in:

Chinese Journal of Cancer Biotherapy, 2022, v. 29, n. 10, p. 921, doi. 10.3872/j.issn.1007-385x.2022.10.008

By:

YANG Peipei;
YANG Junhan;
LIU Mengting;
HUANG Xieping;
XU Ganglin

Publication type:

Article

Expression of uncoupling protein 1 in bovine muscle cells.

Published in:

Journal of Animal Science, 2016, v. 94, n. 12, p. 5097, doi. 10.2527/jas.2016-0726

By:

Abd Eldaim, M. A.;
Hashimoto, O.;
Ohtsuki, H.;
Yamada, T.;
Murakami, M.;
Onda, K.;
Sato, R.;
Kanamori, Y.;
Qiao, Y.;
Tomonaga, S.;
Matsui, T.;
Funaba, M.

Publication type:

Article

Many Faces of Mitochondrial Uncoupling During Age: Damage or Defense?

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2013, v. 68, n. 8, p. 892, doi. 10.1093/gerona/gls332

By:

Bellanti, Francesco;
Romano, Antonino Davide;
Giudetti, Anna Maria;
Rollo, Tiziana;
Blonda, Maria;
Tamborra, Rosanna;
Vendemiale, Gianluigi;
Serviddio, Gaetano

Publication type:

Article

The Interplay between Perioperative Oxidative Stress and Hepatic Dysfunction after Human Liver Resection: A Prospective Observational Pilot Study.

Published in:

Antioxidants, 2024, v. 13, n. 5, p. 590, doi. 10.3390/antiox13050590

By:

Primavesi, Florian;
Senoner, Thomas;
Schindler, Sophie;
Nikolajevic, Aleksandar;
Di Fazio, Pietro;
Csukovich, Georg;
Eller, Silvia;
Neumayer, Bettina;
Anliker, Markus;
Braunwarth, Eva;
Oberhuber, Rupert;
Resch, Thomas;
Maglione, Manuel;
Cardini, Benno;
Niederwieser, Thomas;
Gasteiger, Silvia;
Klieser, Eckhard;
Tilg, Herbert;
Schneeberger, Stefan;
Neureiter, Daniel

Publication type:

Article

Abscisic Acid and Its Receptors LANCL1 and LANCL2 Control Cardiomyocyte Mitochondrial Function, Expression of Contractile, Cytoskeletal and Ion Channel Proteins and Cell Proliferation via ERRα.

Published in:

Antioxidants, 2023, v. 12, n. 9, p. 1692, doi. 10.3390/antiox12091692

By:

Spinelli, Sonia;
Guida, Lucrezia;
Passalacqua, Mario;
Magnone, Mirko;
Cossu, Vanessa;
Sambuceti, Gianmario;
Marini, Cecilia;
Sturla, Laura;
Zocchi, Elena

Publication type:

Article

Mitochondria Need Their Sleep: Redox, Bioenergetics, and Temperature Regulation of Circadian Rhythms and the Role of Cysteine-Mediated Redox Signaling, Uncoupling Proteins, and Substrate Cycles.

Published in:

Antioxidants, 2023, v. 12, n. 3, p. 674, doi. 10.3390/antiox12030674

By:

Richardson, Richard B.;
Mailloux, Ryan J.

Publication type:

Article

Inhibition of Mitochondrial Uncoupling Proteins Arrests Human Spermatozoa Motility without Compromising Viability.

Published in:

Antioxidants, 2023, v. 12, n. 2, p. 409, doi. 10.3390/antiox12020409

By:

Carrageta, David F.;
Freire-Brito, Laís;
Guerra-Carvalho, Bárbara;
Ribeiro, João C.;
Monteiro, Bruno S.;
Barros, Alberto;
Oliveira, Pedro F.;
Monteiro, Mariana P.;
Alves, Marco G.

Publication type:

Article

CoQ Regulates Brown Adipose Tissue Respiration and Uncoupling Protein 1 Expression.

Published in:

Antioxidants, 2023, v. 12, n. 1, p. 14, doi. 10.3390/antiox12010014

By:

Chang, Ching-Fang;
Gunawan, Amanda L.;
Liparulo, Irene;
Zushin, Peter-James H.;
Bertholet, Ambre M.;
Kirichok, Yuriy;
Stahl, Andreas

Publication type:

Article

Membrane Lipid Reshaping Underlies Oxidative Stress Sensing by the Mitochondrial Proteins UCP1 and ANT1.

Published in:

Antioxidants, 2022, v. 11, n. 12, p. 2314, doi. 10.3390/antiox11122314

By:

Jovanović, Olga;
Chekashkina, Ksenia;
Škulj, Sanja;
Žuna, Kristina;
Vazdar, Mario;
Bashkirov, Pavel V.;
Pohl, Elena E.

Publication type:

Article

Decreased basal thermogenesis is associated with the downregulation of cellular metabolic activity of organs and serum thyroid hormones in fasting Eurasian Tree Sparrows (Passer montanus).

Published in:

Avian Research, 2025, v. 16, n. 1, p. 1, doi. 10.1016/j.avrs.2024.100220

By:

Hong Jin;
Qi Xia;
Ziqing Gao;
Yujie XuanYuan;
Beibei Dong;
Ming Li;
Qingjian Liang;
Jinsong Liu

Publication type:

Article

Largely ignored—but pathogenetically significant: ambient temperature in rodent sepsis models.

Published in:

Intensive Care Medicine Experimental, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40635-024-00693-w

By:

Bauer, Reinhard

Publication type:

Article

A potential herbal component for the future treatment of fatty liver disease: Geniposide from gardenia.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1610676

By:

Zhang, Qinyao;
Li, Ziyan;
Wang, Lina

Publication type:

Article

Mirabegron induces selective changes in the faecal microbiota of HFHFr rats without altering bile acid composition.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1547749

By:

Bentanachs, Roger;
Miró, Lluïsa;
Ramírez-Carrasco, Patricia;
Sánchez, Rosa M.;
Bernabeu, Manuel;
Amat, Concepció;
Alegret, Marta;
Pérez-Bosque, Anna;
Roglans, Núria;
Laguna, Juan C.

Publication type:

Article

Genipin attenuates oxidative damage in periodontal tissues by alleviating mitochondrial dysfunction and abnormal glucose uptake through inhibition of UCP2.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1446574

By:

Deng, Yu;
Fu, Ruobing;
Shang, Yaqi;
Hu, Mengting;
Xin, Xirui;
Hou, Yubo;
Yu, Weixian;
Liu, Xinchan

Publication type:

Article

Attenuation of brown adipocyte whitening in high‐fat diet‐induced obese rats: Effects of melatonin and β‐hydroxybutyrate on Cidea, Fsp27 and MT1 expression.

Published in:

Diabetes, Obesity & Metabolism, 2024, v. 26, n. 10, p. 4551, doi. 10.1111/dom.15810

By:

Maleki, Mohammad Hasan;
Khakshournia, Sara;
Heydarnia, Emad;
Omidi, Fateme;
Taghizadeh, Motahareh;
Zeynolabedinzadeh, Mahroo;
Akbari, Mohammadarian;
Vakili, Omid;
Shafiee, Sayed Mohammad

Publication type:

Article

Topical menthol, a pharmacological cold mimic, induces cold sensitivity, adaptive thermogenesis and brown adipose tissue activation in mice.

Published in:

Diabetes, Obesity & Metabolism, 2024, v. 26, n. 10, p. 4329, doi. 10.1111/dom.15781

By:

Sankina, Polina;
Lal, Roshan;
Khare, Pragyanshu;
von Hörsten, Stephan;
Fester, Lars;
Aggarwal, Vaishali;
Zimmermann, Katharina;
Bishnoi, Mahendra

Publication type:

Article

Human adipose tissue expression of uncoupling protein 1 in response to intravenous administration of B‐type natriuretic peptide hormone: Results from a randomized controlled crossover study.

Published in:

Diabetes, Obesity & Metabolism, 2024, v. 26, n. 8, p. 3458, doi. 10.1111/dom.15628

By:

Bachmann, Katherine N.;
Ceddia, Ryan P.;
Gupta, Deepak K.;
Collins, Sheila;
Wang, Thomas J.

Publication type:

Article

Early weaning alters the thermogenic capacity of brown adipose tissue in adult male and female rats.

Published in:

European Journal of Nutrition, 2020, v. 59, n. 5, p. 2207, doi. 10.1007/s00394-019-02071-9

By:

Peixoto, T. C.;
Pietrobon, C. B.;
Bertasso, I. M.;
Caramez, F. A. H.;
Calvino, C.;
Santos, T. R.;
Oliveira, E.;
Moura, E. G.;
Lisboa, P. C.

Publication type:

Article

The Futile Creatine Cycle powers UCP1-independent thermogenesis in classical BAT.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-58294-4

By:

Bunk, Jakub;
Hussain, Mohammed F.;
Delgado-Martin, Maria;
Samborska, Bozena;
Ersin, Mina;
Shaw, Abhirup;
Rahbani, Janane F.;
Kazak, Lawrence

Publication type:

Article

Hepatic SerpinA1 improves energy and glucose metabolism through regulation of preadipocyte proliferation and UCP1 expression.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53835-9

By:

Okagawa, Shota;
Sakaguchi, Masaji;
Okubo, Yuma;
Takekuma, Yuri;
Igata, Motoyuki;
Kondo, Tatsuya;
Takeda, Naoki;
Araki, Kimi;
Brandao, Bruna Brasil;
Qian, Wei-Jun;
Tseng, Yu-Hua;
Kulkarni, Rohit N.;
Kubota, Naoto;
Kahn, C. Ronald;
Araki, Eiichi

Publication type:

Article

The hexosamine biosynthetic pathway rescues lysosomal dysfunction in Parkinson's disease patient iPSC derived midbrain neurons.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49256-3

By:

Wani, Willayat Y.;
Zunke, Friederike;
Belur, Nandkishore R.;
Mazzulli, Joseph R.

Publication type:

Article

Altered leptin signaling and attenuated cardiac vagal activity in rats with type 2 diabetes.

Published in:

Frontiers in Physiology, 2025, p. 1, doi. 10.3389/fphys.2025.1547901

By:

Evans, Anthony J.;
Tu, Huiyin;
Li, Yu;
Shabaltiy, Boris;
Whitney, Lauren;
Carpenter, Kassidy;
Li, Yu-long

Publication type:

Article

Identification of New Potent Human Uncoupling Protein 1 (UCP1) Agonists Using Virtual Screening and in vitro Approaches.

Published in:

Molecular Informatics, 2019, v. 38, n. 10, p. N.PAG, doi. 10.1002/minf.201900030

By:

Lu, Hong‐Yuan;
Wang, Nan;
Li, Xiang;
Huang, Yuan;
Wang, Jian;
Zhao, Qing‐Chun

Publication type:

Article

Quantifying the utilisation of blue, green and brown resources by riparian predators: A combined use of amino acid isotopes and fatty acids.

Published in:

Methods in Ecology & Evolution, 2024, v. 15, n. 8, p. 1450, doi. 10.1111/2041-210X.14371

By:

Saboret, Grégoire;
Drost, Bastiaan J. W.;
Kowarik, Carmen;
Schubert, Carsten J.;
Gossner, Martin M.;
Ilić, Maja

Publication type:

Article

Early Adipogenesis and Upregulation of UCP1 in Mesenchymal Stromal Cells Stimulated by Devitalized Microfragmented Fat (MiFAT).

Published in:

Journal of Lipids, 2024, v. 2024, p. 1, doi. 10.1155/2024/1318186

By:

Coccè, Valentina;
Missaglia, Sara;
Martegani, Eleonora;
Tavian, Daniela;
Doneda, Luisa;
Manfredi, Barbara;
Alessandri, Giulio;
Corradini, Costantino;
Giannì, Aldo;
Ciusani, Emilio;
Paino, Francesca;
Pessina, Augusto;
Wertz, Philip W.

Publication type:

Article

Associations of Uncoupling Protein 2 Ala55Val and Uncoupling Protein 3-55C/T Polymorphisms with Heart Rate Variability in Young Oarsmen-a Pilot Study.

Published in:

Asian Journal of Sports Medicine, 2019, v. 10, n. 2, p. 1, doi. 10.5812/asjsm.77082

By:

Melnikov, Andrey Aleksandrovich;
Bobylev, Artem Sergeevich;
Varfolomeeva, Zoya Semenovna

Publication type:

Article

Pinealectomy increases thermogenesis and decreases lipogenesis.

Published in:

Molecular Medicine Reports, 2020, v. 22, n. 5, p. 4289

By:

Kim, Mikyung;
Lee, So Min;
Jung, Jeeyoun;
Kim, Yun Jin;
Moon, Kyo Chul;
Seo, Ji Hae;
Ha, Tae Kyung;
Ha, Eunyoung

Publication type:

Article

Pilot study and bioinformatics analysis of differentially expressed genes in adipose tissues of rats with excess dietary intake.

Published in:

Molecular Medicine Reports, 2020, v. 21, n. 5, p. 2063, doi. 10.3892/mmr.2020.11012

By:

Yuan, Jun Chao;
Yogarajah, Thaneswary;
Lim, Shern Kwok;
Tee, Get Bee Yvonne;
Khoo, Boon Yin

Publication type:

Article

UCP2 silencing aggravates mitochondrial dysfunction in astrocytes under septic conditions.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 5, p. 4459, doi. 10.3892/mmr.2019.10721

By:

Peng, Wanwan;
Huang, Jinda;
Zheng, Yijun;
Ding, Yue;
Li, Sitao;
Zhang, Junliang;
Lyu, Juanjuan;
Zeng, Qiyi

Publication type:

Article

PEDF protects human retinal pigment epithelial cells against oxidative stress via upregulation of UCP2 expression.

Published in:

Molecular Medicine Reports, 2019, v. 19, n. 1, p. 59

By:

Wang, Xia;
Liu, Xu;
Ren, Yuan;
Liu, Ying;
Han, Shuangyu;
Zhao, Jingkang;
Gou, Xingchun;
He, Yuan

Publication type:

Article

Apolipoprotein A5 regulates intracellular triglyceride metabolism in adipocytes.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 5, p. 6771, doi. 10.3892/mmr.2017.7461

By:

XIAO‑YAN ZHENG;
BI‑LIAN YU;
YU‑FEI XIE;
SHUI‑PING ZHAO;
CHEN‑LU WU

Publication type:

Article

Mechanism of uncoupling protein 2-mediated myocardial injury in hypothermic preserved rat hearts.

Published in:

Molecular Medicine Reports, 2016, v. 14, n. 2, p. 1857, doi. 10.3892/mmr.2016.5436

By:

GAI-GE CHEN;
JIN-BIN YAN;
XU-MING WANG;
MING-ZHI ZHENG;
JIAN-PING JIANG;
XIN-MEI ZHOU;
BIN CAI;
YUE-LIANG SHEN

Publication type:

Article

Sirtuin 1 activation enhances the PGC-1α/mitochondrial antioxidant system pathway in status epilepticus.

Published in:

Molecular Medicine Reports, 2015, v. 11, n. 1, p. 521, doi. 10.3892/mmr.2014.2724

By:

SHENG-JUN WANG;
XIU-HE ZHAO;
WEN CHEN;
NING BO;
XIAN-JIN WANG;
ZHAO-FU CHI;
WEI WU

Publication type:

Article

Oleanolic Acid Derivative AXX-18 Exerts Antiviral Activity by Inhibiting the Expression of HSV-1 Viral Genes UL8 and UL52.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 6, p. N.PAG, doi. 10.3390/v14061287

By:

Wang, Zhaoyang;
Jia, Jiaoyan;
Jiang, Yuzhou;
Li, Feng;
Wang, Yiliang;
Song, Xiaowei;
Qin, Shurong;
Wang, Yifei;
Zheng, Kai;
Hu, Binyuan;
Cheng, Yongxian;
Ren, Zhe

Publication type:

Article

A Standardized Aframomum melegueta Seed Extract Regulates Browning of White Adipose Tissue in High-Fat Diet Model Mice..

Published in:

Natural Product Communications, 2021, v. 16, n. 9, p. 1, doi. 10.1177/1934578X211033744

By:

Sudeep, Heggar Venkataramana;
Ramanaiah, Illuri;
Amritha, Raj;
Naveen, Puttaswamy;
Gouthamchandra, Kuluvar;
Shyamprasad, Kodimule

Publication type:

Article

Association between Uncoupling Protein 2 Gene Ala55val Polymorphism and Sudden Sensorineural Hearing Loss.

Published in:

Journal of International Advanced Otology, 2018, v. 14, n. 2, p. 166, doi. 10.5152/iao.2018.5442

By:

Yusuke Koide;
Masaaki Teranishi;
Saiko Sugiura;
Yasue Uchida;
Naoki Nishio;
Ken Kato;
Hironao Otake;
Tadao Yoshida;
Rei Otsuka;
Fujiko Ando;
Hiroshi Shimokata;
Yasuhisa Hasegawa;
Tsutomu Nakashima;
Michihiko Sone

Publication type:

Article