Works about TUMOR suppressor genes

Results: 5000

Making sense of human colorectal cancer molecular subtypes: mice are stepping in.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02594-7

By:

Green, Caleb;
Roccia, Pamela;
Rufini, Alessandro

Publication type:

Article

From hyperplasia to carcinoma: a molecular driven adrenal disease.

Published in:

European Journal of Endocrinology, 2025, v. 192, n. 6, p. K55, doi. 10.1093/ejendo/lvaf105

By:

Dybal, Elisa;
Decaussin-Petrucci, Myriam;
Descotes, Françoise;
Raverot, Gérald;
Lifante, Jean-Christophe;
Sajous, Christophe;
Lopez, Jonathan;
Lasolle, Hélène

Publication type:

Article

Immune profiling of premalignant lesions in patients with Peutz‐Jeghers syndrome.

Published in:

United European Gastroenterology Journal, 2025, v. 13, n. 3, p. 338, doi. 10.1002/ueg2.12650

By:

Liu, Zhongyue;
Wu, Boda;
Shi, Xiaoliu;
Zhou, Junfeng;
Huang, Hui;
Li, Zhihong;
Yang, Mei

Publication type:

Article

E3 ubiquitin-protein ligase CBL inhibits non-small cell lung cancer progression via ubiquitination and degradation of KDR.

Published in:

Cell Division, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13008-025-00159-9

By:

Tu, Zhiyue;
Shen, Yongshuai;
Li, Hua

Publication type:

Article

Integrated proteomics and transcriptomics analysis reveals key regulatory genes between ER-positive/PR-positive and ER-positive/PR-negative breast cancer.

Published in:

BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-025-14451-y

By:

Lu, Zhengjia;
Yang, Jiao;
Feng, Yang;
Ming, Jia

Publication type:

Article

miR-4435对鼻咽癌细胞生物学行为的影响研究.

Published in:

Journal of Modern Medicine & Health, 2025, v. 41, n. 6, p. 1297, doi. 10.3969/j.issn.1009-5519.2025.06.001

By:

王挺;
张杨;
郭洁;
范崇盛;
蒋伟

Publication type:

Article

Acute PM2.5 Exposure in Distinct NSCLC Cell Lines Reveals Strong Oxidative Stress and Therapy Resistance Signatures Through Transcriptomic Analysis.

Published in:

Toxics, 2025, v. 13, n. 6, p. 484, doi. 10.3390/toxics13060484

By:

Panya, Aussara;
Thongyim, Saruda;
Sattayawat, Pachara;
Inwongwan, Sahutchai

Publication type:

Article

The role of pioneering transcription factors, chromatin accessibility and epigenetic reprogramming in oncogenic viruses.

Published in:

Frontiers in Microbiology, 2025, p. 1, doi. 10.3389/fmicb.2025.1602497

By:

Kgatle, Mankgopo;
Mbambara, Saidon;
Khoza, Leon;
Fadebi, Olalekan;
Mashamba-Thompson, Tivani;
Sathekge, Mike

Publication type:

Article

Targeting the p53/xCT/GSH Axis with PRIMA-1 Met Combined with Sulfasalazine Shows Therapeutic Potential in Chronic Lymphocytic Leukemia.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5559, doi. 10.3390/ijms26125559

By:

Pasino, Martina;
Speciale, Andrea;
Ravera, Silvia;
Cutrona, Giovanna;
Massara, Rosanna;
Bertola, Nadia;
Viale, Maurizio;
Velkova, Irena;
Mazzarello, Andrea Nicola;
Fais, Franco;
Loiacono, Fabrizio;
Matis, Serena;
Valenti, Giulia Elda;
Traverso, Nicola;
Domenicotti, Cinzia;
Marengo, Barbara;
Tasso, Bruno;
Ibatici, Adalberto;
Angelucci, Emanuele;
Vaisitti, Tiziana

Publication type:

Article

Colorectal Cancer Biomarker Identification via Joint DNA-Methylation and Transcriptomics Analysis Workflow.

Published in:

Genes, 2025, v. 16, n. 6, p. 620, doi. 10.3390/genes16060620

By:

Oladapo, Olajumoke B.;
Moussa, Marmar R.

Publication type:

Article

A De Novo PTEN Pathogenic Variant in a Young Girl with Sporadic Cowden Syndrome—A Case Report.

Published in:

Pediatric Reports, 2025, v. 17, n. 3, p. 54, doi. 10.3390/pediatric17030054

By:

Gebhart, Paulina;
Singer, Christian;
Muhr, Daniela;
Stein, Christina;
Tan, Yen Y.

Publication type:

Article

The Nuclear Effector of Wnt-Signaling, Tcf1, Functions as a T-Cell–Specific Tumor Suppressor for Development of Lymphomas

Published in:

PLoS Biology, 2012, v. 10, n. 11, p. 1, doi. 10.1371/journal.pbio.1001430

By:

Tiemessen, Machteld M.;
Baert, Miranda R. M.;
Schonewille, Tom;
Brugman, Martijn H.;
Famili, Farbod;
Salvatori, Daniela C. F.;
Meijerink, Jules P. P.;
Ozbek, Ugur;
Clevers, Hans;
van Dongen, Jacques J. M.;
Staal, Frank J. T.

Publication type:

Article

Robust Target Gene Discovery through Transcriptome Perturbations and Genome-Wide Enhancer Predictions in Drosophila Uncovers a Regulatory Basis for Sensory Specification.

Published in:

PLoS Biology, 2010, v. 8, n. 7, p. 1, doi. 10.1371/journal.pbio.1000435

By:

Aerts, Stein;
Xiao-Jiang Quan;
Claeys, Annelies;
Sanchez, Marina Naval;
Tate, Phillip;
Jiekun Yan;
Hassan, Bassem A.

Publication type:

Article

ATP and MO25α Regulate the Conformational State of the STRADα Pseudokinase and Activation of the LKB1 Tumour Suppressor.

Published in:

PLoS Biology, 2009, v. 7, n. 6, p. 1, doi. 10.1371/journal.pbio.1000126

By:

Zeqiraj, Elton;
Filippi, Beatrice Maria;
Goldie, Simon;
Navratilova, Iva;
Boudeau, Jérôme;
Deak, Maria;
Alessi, Dario R.;
van Aalten, Daan M. F.

Publication type:

Article

Atonal homolog 1 Is a Tumor Suppressor Gene.

Published in:

PLoS Biology, 2009, v. 7, n. 2, p. e1000039, doi. 10.1371/journal.pbio.1000039

By:

Bossuyt, Wouter;
Kazanjian, Avedis;
De Geest, Natalie;
Van Kelst, Sofie;
De Hertogh, Gert;
Geboes, Karel;
Boivin, Greg P.;
Luciani, Judith;
Fuks, Francois;
Chuah, Marinee;
VandenDriessche, Thierry;
Marynen, Peter;
Cools, Jan;
Shroyer, Noah F.;
Hassan, Bassem A.

Publication type:

Article

The Atonal Proneural Transcription Factor Links Differentiation and Tumor Formation in Drosophila.

Published in:

PLoS Biology, 2009, v. 7, n. 2, p. e1000040, doi. 10.1371/journal.pbio.1000040

By:

Bossuyt, Wouter;
De Geest, Natalie;
Aerts, Stein;
Leenaerts, Iris;
Marynen, Peter;
Hassan, Bassem A.

Publication type:

Article

Genetic Analysis of Pathways Regulated by the von Hippel-Lindau Tumor Suppressor in Caenorhabditis elegans.

Published in:

PLoS Biology, 2004, v. 2, n. 9, p. 1, doi. 10.1371/journal.pbio.0020289

By:

Bishop, Tammie;
Lau, Kah Weng;
Epstein, Andrew C. R;
Kim, Stuart K;
Jiang, Min;
O'Rourke, Delia;
Pugh, Christopher W;
Gleadle, Jonathan M;
Taylor, Martin S;
Hodgkin, Jonathan;
Ratcliffe, Peter J

Publication type:

Article

Continued Colonization of the Human Genome by Mitochondrial DNA.

Published in:

PLoS Biology, 2004, v. 2, n. 9, p. 1, doi. 10.1371/journal.pbio.0020273

By:

Ricchetti, Miria;
Tekaia, Fredj;
Dujon, Bernard

Publication type:

Article

Many Ribosomal Protein Genes Are Cancer Genes in Zebrafish.

Published in:

PLoS Biology, 2004, v. 2, n. 5, p. 1, doi. 10.1371/journal.pbio.0020139

By:

Amsterdam, Adam;
Sadler, Kirsten C;
Lai, Kevin;
Farrington, Sarah;
Bronson, Roderick T;
Lees, Jacqueline A;
Hopkins, Nancy

Publication type:

Article

Many Ribosomal Protein Genes Are Cancer Genes in Zebrafish.

Published in:

PLoS Biology, 2004, v. 2, n. 5, p. 690, doi. 10.1371/journal.pbio.0020139

By:

Amsterdam, Adam;
Sadler, Kirsten C.;
Lai, Kevin;
Farrington, Sarah;
Bronson, Roderick T.;
Lees, Jacqueline A.;
Hopkins, Nancy

Publication type:

Article

Tumour Suppressor Genes—One Hit Can Be Enough.

Published in:

PLoS Biology, 2004, v. 2, n. 2, p. 1, doi. 10.1371/journal.pbio.0020040

By:

Hohenstein, Peter

Publication type:

Article

Treatment of Terminal Peritoneal Carcinomatosis by a Transducible p53-Activating Peptide.

Published in:

PLoS Biology, 2004, v. 2, n. 2, p. 1, doi. 10.1371/journal.pbio.0020036

By:

Snyder, Eric L;
Meade, Bryan R;
Saenz, Cheryl C;
Dowdy, Steven F

Publication type:

Article

Tumour Suppressor Genes--One Hit Can Be Enough.

Published in:

PLoS Biology, 2004, v. 2, n. 2, p. 0165, doi. 10.1371/journal.pbio.0020040

By:

Hohenstein, Peter

Publication type:

Article

Inhibition of HIF2α Is Sufficient to Suppress pVHL-Defective Tumor Growth.

Published in:

PLoS Biology, 2003, v. 1, n. 12, p. 1, doi. 10.1371/journal.pbio.0000083

By:

Kondo, Keiichi;
Kim, William Y;
Lechpammer, Mirna;
Kaelin Jr, William G

Publication type:

Article

Inhibition of HIF2 a Is Sufficient to Suppress pVHL-Defective Tumor Growth.

Published in:

PLoS Biology, 2003, v. 1, n. 3, p. 339, doi. 10.1371/journal.pbio.0000083

By:

Kondo, Keiichi;
Kim, William Y.;
Lechpammer, Mirna;
Kaelin Jr., William G.

Publication type:

Article

Pten Dose Dictates Cancer Progression in the Prostate.

Published in:

PLoS Biology, 2003, v. 1, n. 3, p. 385, doi. 10.1371/journal.pbio.0000059

By:

Trotman, Lloyd C.;
Niki, Masaru;
Dotan, Zohar A.;
Koutcher, Jason A.;
Di Cristofano, Antinio;
Xiao, Andrew;
Khoo, Alan S.;
Roy-Burman, Pradip;
Greenberg, Norman M.;
Van Dyke, Terry;
Cordon-Cardo, Carlos;
Pandolfi, Pier Paolo

Publication type:

Article

Pten Dose Dictates Cancer Progression in the Prostate.

Published in:

PLoS Biology, 2003, v. 1, n. 10, p. 1, doi. 10.1371/journal.pbio.0000059

By:

Trotman, Lloyd C;
Niki, Masaru;
Dotan, Zohar A;
Koutcher, Jason A;
Di Cristofano, Antonio;
Xiao, Andrew;
Khoo, Alan S;
Roy-Burman, Pradip;
Greenberg, Norman M;
Dyke, Terry Van;
Cordon-Cardo, Carlos;
Pandolfi, Pier Paolo

Publication type:

Article

The Roles of APC and Axin Derived from Experimental and Theoretical Analysis of the Wnt Pathway.

Published in:

PLoS Biology, 2003, v. 1, n. 1, p. 116, doi. 10.1371/journal.pbio.0000010

By:

Lee, Ethan;
Salic, Adrian;
Kruger, Roland;
Heinrich, Reinhart;
Kirschner, Marc W.

Publication type:

Article

Infusing Bioinformatics and Research-Like Experience into a Molecular Biology Laboratory Course.

Published in:

Bioscene, 2014, v. 40, n. 2, p. 3

By:

Nogaj, Luiza A.

Publication type:

Article

Association of a potential functional pre-miR-218 polymorphism and its interaction with hepatitis B virus mutations with hepatocellular carcinoma risk.

Published in:

Liver International, 2014, v. 34, n. 5, p. 728, doi. 10.1111/liv.12313

By:

Han, Yifang;
Pu, Rui;
Han, Xue;
Zhao, Jun;
Li, Weiping;
Yin, Jianhua;
Zhang, Yuwei;
Shen, Qiuxia;
Xie, Jiaxin;
Zhang, Qi;
Jiang, Shuang;
Li, Juhong;
Zhang, Hongwei;
Wang, Hongyang;
Cao, Guangwen

Publication type:

Article

Deleted in liver cancer 2 suppresses cell growth via the regulation of the Raf-1–ERK1/2–p70S6K signalling pathway.

Published in:

Liver International, 2010, v. 30, n. 9, p. 1315, doi. 10.1111/j.1478-3231.2010.02307.x

By:

Thomas Ho-Yin Leung;
Judy Wai-Ping Yam;
Lo Kong Chan;
Yick-Pang Ching;
Irene Oi-Lin Ng

Publication type:

Article

Promoter methylation and loss of coding exons of the fragile histidine triad (FHIT) gene in intrahepatic cholangiocarcinomas.

Published in:

Liver International, 2005, v. 25, n. 6, p. 1202, doi. 10.1111/j.1478-3231.2005.01174.x

By:

Foja, S.;
Goldberg, M.;
Schagdarsurengin, U.;
Dammann, R.;
Tannapfel, A.;
Ballhausen, W. G.

Publication type:

Article

p53 mutations in human cholangiocarcinoma: a review.

Published in:

Liver International, 2005, v. 25, n. 4, p. 704, doi. 10.1111/j.1478-3231.2005.01106.x

By:

Khan, Shahid A.;
Thomas, Howard C.;
Toledano, Mireille B.;
Cox, I . Jane;
Taylor-Robinson, Simon D.

Publication type:

Article

Rosline promotes p21 expression to inhibit ovarian cancer cell proliferation via p53‐independent pathway.

Published in:

Journal of Obstetrics & Gynaecology Research, 2023, v. 49, n. 8, p. 2126, doi. 10.1111/jog.15708

By:

Zhao, Ting;
Xiao, Xiao;
Li, Lingchuan;
Wu, Xiaomei;
Yuan, Tao

Publication type:

Article

The possible impact of DNA‐binding chromodomain‐helicase 5 polymorphisms on male infertility: A case–control study.

Published in:

Journal of Obstetrics & Gynaecology Research, 2023, v. 49, n. 4, p. 1214, doi. 10.1111/jog.15560

By:

Moudi, Bita;
Asemi‐Rad, Azam;
Sheibak, Nadia;
Heidari, Zahra;
Mahmoudzadeh‐Sagheb, Hamidreza

Publication type:

Article

LncRNA HCG11 represses ovarian cancer cell growth via AKT signaling pathway.

Published in:

Journal of Obstetrics & Gynaecology Research, 2022, v. 48, n. 3, p. 796, doi. 10.1111/jog.15083

By:

Chen, Xiaoping;
Yang, Yusheng;
Sun, Jie;
Hu, Chaofeng;
Ge, Xiaohong;
Li, Rong

Publication type:

Article

MiR‐326 regulates the proliferation and apoptosis of endometrial cancer by targeting Bcl‐2.

Published in:

Journal of Obstetrics & Gynaecology Research, 2021, v. 47, n. 2, p. 621, doi. 10.1111/jog.14572

By:

Cai, Lily;
Chen, Juan‐Juan;
Deng, Fu‐Mou;
Wang, Lei;
Chen, Yu

Publication type:

Article

Prognostic role of maspin expression in patients with cervical dysplasia and cervical cancer.

Published in:

Journal of Obstetrics & Gynaecology Research, 2020, v. 46, n. 5, p. 759, doi. 10.1111/jog.14225

By:

Isci Bostanci, Esra;
Guler, Ismail;
Dikmen, Asiye U.;
Erdem, Ozlem;
Guner, Haldun;
Onan, Mehmet Anil;
Taskiran, Cagatay

Publication type:

Article

Letter to ‘Placental mesenchymal dysplasia with severe fetal growth restriction in one placenta of a dichorionic diamniotic twin pregnancy’: Study on twin placenta as a natural experiment.

Published in:

2018

By:

Takahashi, Hironori;
Matsubara, Shigeki

Publication type:

Letter to the Editor

Wilms' tumor 1 protein expression in endometrial adenocarcinoma and endometrial intra-epithelial neoplasia.

Published in:

Journal of Obstetrics & Gynaecology Research, 2016, v. 42, n. 7, p. 870, doi. 10.1111/jog.12981

By:

Atik, Yeliz;
Cetinkaya Demir, Bilge;
Ozan, Hakan;
Baykara, Sema;
Usubutun, Alp;
Yılmaz Erturk, Fatma

Publication type:

Article

Characterization of TP53 and PI3K signaling pathways as molecular targets in gynecologic malignancies.

Published in:

2016

By:

Oda, Katsutoshi;
Ikeda, Yuji;
Kashiyama, Tomoko;
Miyasaka, Aki;
Inaba, Kanako;
Fukuda, Tomohiko;
Asada, Kayo;
Sone, Kenbun;
Wada ‐ Hiraike, Osamu;
Kawana, Kei;
Osuga, Yutaka;
Fujii, Tomoyuki

Publication type:

Other

miR-205 promotes epithelial-mesenchymal transition by targeting AKT signaling in endometrial cancer cells.

Published in:

Journal of Obstetrics & Gynaecology Research, 2015, v. 41, n. 10, p. 1653, doi. 10.1111/jog.12756

By:

Jin, Chenyu;
Liang, Ruojia

Publication type:

Article

Indigo Carmine as New Label in PNA Biosensor for Detection of Short Sequence of p53 Tumor Suppressor Gene.

Published in:

Electroanalysis, 2013, v. 25, n. 9, p. 2075, doi. 10.1002/elan.201300155

By:

Hamidi‐Asl, Ezat;
Raoof, Jahan Bakhsh;
Ojani, Reza;
Hejazi, Mohammad Saeid

Publication type:

Article

Molecular genetic profiling reveals novel association between FLT3 mutation and survival in glioma.

Published in:

Journal of Neuro-Oncology, 2020, v. 148, n. 3, p. 473, doi. 10.1007/s11060-020-03567-9

By:

Shee, Kevin;
Chambers, Meagan;
Hughes, Edward G.;
Almiron, Damian A.;
Deharvengt, Sophie J.;
Green, Donald;
Lefferts, Joel A.;
Andrew, Angeline S.;
Hickey, William F.;
Tsongalis, Gregory J.

Publication type:

Article

Analysis of CDKN2A gene alterations in recurrent and non-recurrent meningioma.

Published in:

Journal of Neuro-Oncology, 2019, v. 145, n. 3, p. 449, doi. 10.1007/s11060-019-03333-6

By:

Guyot, Anne;
Duchesne, Mathilde;
Robert, Sandrine;
Lia, Anne-Sophie;
Derouault, Paco;
Scaon, Erwan;
Lemnos, Leslie;
Salle, Henri;
Durand, Karine;
Labrousse, François

Publication type:

Article

SPINT2 is hypermethylated in both IDH1 mutated and wild-type glioblastomas, and exerts tumor suppression via reduction of c-Met activation.

Published in:

Journal of Neuro-Oncology, 2019, v. 142, n. 3, p. 423, doi. 10.1007/s11060-019-03126-x

By:

Liu, Fei;
Cox, Christopher D.;
Chowdhury, Reshmi;
Dovek, Laura;
Nguyen, Huytram;
Li, Tie;
Li, Sichen;
Ozer, Byram;
Chou, Arthur;
Nguyen, Nhung;
Wei, Bowen;
Antonios, Joseph;
Soto, Horacio;
Kornblum, Harley;
Liau, Linda;
Prins, Robert;
Nghiemphu, P. Leia;
Yong, William;
Cloughesy, Timothy;
Lai, Albert

Publication type:

Article

Targeted next-generation sequencing panel (TruSight Tumor 170) in diffuse glioma: a single institutional experience of 135 cases.

Published in:

Journal of Neuro-Oncology, 2019, v. 142, n. 3, p. 445, doi. 10.1007/s11060-019-03114-1

By:

Na, Kiyong;
Kim, Hyun-Soo;
Shim, Hyo Sup;
Chang, Jong Hee;
Kang, Seok-Gu;
Kim, Se Hoon

Publication type:

Article

Functional relevance of genes predicted to be affected by epigenetic alterations in atypical teratoid/rhabdoid tumors.

Published in:

Journal of Neuro-Oncology, 2019, v. 141, n. 1, p. 43, doi. 10.1007/s11060-018-03018-6

By:

Tegeder, Isabel;
Thiel, Katharina;
Erkek, Serap;
Johann, Pascal D.;
Berlandi, Johannes;
Thatikonda, Venu;
Frühwald, Michael C.;
Kool, Marcel;
Jeibmann, Astrid;
Hasselblatt, Martin

Publication type:

Article

MicroRNA-1231 exerts a tumor suppressor role through regulating the EGFR/PI3K/AKT axis in glioma.

Published in:

Journal of Neuro-Oncology, 2018, v. 139, n. 3, p. 547, doi. 10.1007/s11060-018-2903-8

By:

Zhang, Jiale;
Zhang, Jie;
Qiu, Wenjin;
Zhang, Jian;
Li, Yangyang;
Kong, Enjun;
Lu, Ailin;
Xu, Jia;
Lu, Xiaoming

Publication type:

Article

Double somatic <italic>SMARCB1</italic> and <italic>NF2</italic> mutations in sporadic spinal schwannoma.

Published in:

Journal of Neuro-Oncology, 2018, v. 137, n. 1, p. 33, doi. 10.1007/s11060-017-2711-6

By:

Paganini, Irene;
Capone, Gabriele Lorenzo;
Vitte, Jeremie;
Sestini, Roberta;
Putignano, Anna Laura;
Giovannini, Marco;
Papi, Laura

Publication type:

Article