Works about TUMOR microenvironment

Results: 5000

DCIS‐like invasive carcinoma of the breast with tumour‐associated microvasculature mimicking myoepithelium: a diagnostic pitfall.

Published in:

Histopathology, 2025, v. 87, n. 2, p. 246, doi. 10.1111/his.15459

By:

Salisbury, Taylor;
Rendi, Mara;
Bhalli, Rabia;
Bean, Gregory R;
Allison, Kimberly H;
Troxell, Megan L

Publication type:

Article

TIGAR regulated by HPV E6 is correlated with disease stage, drug sensitivity, and immune microenvironment in cervical cancer.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-07201-4

By:

Liu, Yameng;
Zhang, Yu;
Zhang, Hailong;
Xu, Dianqin;
Zhou, Xinzhu;
Xie, Luhong;
Xi, Hongli;
Zhu, Yurong;
Yang, Hanlin;
Zhu, Xiaoyu;
Ren, Ji;
Min, Shaoju;
Tan, Yujie

Publication type:

Article

Single-cell transcriptomics analysis reveals a disrupted NK-T cell interaction network in liver metastatic cancer.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-06241-0

By:

Wang, Xiaoshuang;
Wu, Zhongen;
Zhou, Yan;
Yang, Dehua;
Zhou, Qingtong;
Zhu, Di;
Wang, Ming-Wei;
Wang, Lu

Publication type:

Article

The prognostic significance of the NMD core factor UPF1 in low-grade glioma.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-05711-9

By:

Yang, Shuo;
Wu, Na;
Duan, Yumeng;
Qi, Shasha;
Yuan, Shuo;
Lu, Huixia

Publication type:

Article

CT radiomics-based intratumoral and intertumoral heterogeneity indicators for prognosis prediction in gastric cancer patients receiving neoadjuvant chemotherapy.

Published in:

European Radiology, 2025, v. 35, n. 8, p. 4448, doi. 10.1007/s00330-025-11430-6

By:

Li, Jiazheng;
Li, Zhenhui;
Wang, Yinkui;
Li, Yuzhuo;
Zhang, Jing;
Li, Ziyu;
Tang, Lei

Publication type:

Article

Deciphering the intratumoral histologic heterogeneity of lung adenocarcinoma using radiomics.

Published in:

European Radiology, 2025, v. 35, n. 8, p. 4861, doi. 10.1007/s00330-025-11397-4

By:

Koo, Jae Mo;
Kim, Jonghoon;
Lee, Junghee;
Hwang, Soohyun;
Shim, Hyo Sup;
Hong, Tae Hee;
Oh, Yu Jin;
Kim, Hong Kwan;
Lee, Chang Young;
Park, Byung Jo;
Lee, Ho Yun

Publication type:

Article

Aquaglyceroporin-7 ameliorates sorafenib resistance and immune evasion in hepatocellular carcinoma through inhibition of lipid accumulation.

Published in:

Cellular & Molecular Life Sciences, 2025, v. 82, n. 1, p. 1, doi. 10.1007/s00018-025-05801-x

By:

He, Guangsi;
Shao, Wenzhu;
Wang, Weifei;
Sun, Lu;
Gao, Beibei;
Wei, Jie

Publication type:

Article

Inhibitory Microenvironment Remodeling Enhances STING Activation for Solid Tumor Immunotherapy.

Published in:

Advanced Functional Materials, 2025, v. 35, n. 27, p. 1, doi. 10.1002/adfm.202421849

By:

Fang, Wenming;
Chen, Lizhu;
Hu, Ping;
Shi, Jianlin

Publication type:

Article

Tumor microenvironment responsive nanodrugs for synergistic chemo-chemodynamic therapy in triple negative breast cancer.

Published in:

Journal of Nanoparticle Research, 2025, v. 27, n. 6, p. 1, doi. 10.1007/s11051-025-06346-7

By:

Shi, Haonan;
Li, Tao

Publication type:

Article

The role of JPT1 in hepatocellular carcinoma: tumor progression, microtubule dynamics regulation, and potential mechanisms within the immune microenvironment.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03066-1

By:

Lu, Yipin;
Xu, Peng;
Li, Sha;
Yao, Jie

Publication type:

Article

Precision immune regulation in KRAS-mutated cancers: the final piece of the puzzle?

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03444-1

By:

Fu, Shenao;
Ma, Jiayao;
Cai, Changjing;
Tan, Jun;
Deng, Xiangying;
Shen, Hong;
Zeng, Shan;
Chen, Yihong;
Han, Ying

Publication type:

Article

Resistance mechanisms and approach to chronic lymphocytic leukemia after BTK inhibitor therapy.

Published in:

Leukemia & Lymphoma, 2025, v. 66, n. 7, p. 1176, doi. 10.1080/10428194.2025.2466101

By:

Gruessner, Christine;
Wiestner, Adrian;
Sun, Clare

Publication type:

Article

Spatially resolved C1QC<sup>+</sup> macrophage-CD4<sup>+</sup> T cell niche in colorectal cancer microenvironment: implications for immunotherapy response.

Published in:

Cell Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41421-025-00811-2

By:

Zhang, Hangyu;
Hong, Libing;
Dong, Zhen;
Xin, Shan;
Lin, Bo;
Cheng, Jinlin;
Tian, Weihong;
Li, Bin;
Wang, Jing;
Liu, Xiaoyan;
Liu, Chuan;
Jin, Yuzhi;
Feng, Yanzhi;
Su, Ge;
Sun, Xuqi;
Liu, Qiqi;
Dai, Xiaomeng;
Gao, Yang;
Tong, Zhou;
Liu, Lulu

Publication type:

Article

CyTOF as a suitable tool for stratification and monitoring of cancer patients.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06764-0

By:

Seliger, Barbara;
Massa, Chiara

Publication type:

Article

Robo1 CAR-NK92 and radiotherapy exert synergistic efficacy in solid tumors.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06753-3

By:

Wu, Mengdi;
He, Jie;
Geng, Jiaxiao;
Wei, Zhiming;
Cheng, Rong;
Li, Huashun;
Xing, Ligang

Publication type:

Article

Petiveria alliacea and Caesalpinia spinosa extracts reduce the generation of cancer-associated fibroblasts in a 3D platform representative of the tumor microenvironment.

Published in:

Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03860-5

By:

Jimenez, María Camila;
Lasso, Paola;
Fiorentino, Susana;
Barreto, Alfonso

Publication type:

Article

Identification of molecular subtypes based on pseudouridine modification in hepatocellular carcinoma.

Published in:

Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03844-5

By:

Xu, Weifeng;
Nie, Caiyun;
Liu, Zhen;
Liu, Yingjun;
Yu, Penghui;
Lv, Huifang;
Chen, Beibei;
Wang, Jianzheng;
Wang, Saiqi;
Zhao, Jing;
He, Yunduan;
Gao, Shegan;
Chen, Xiaobing

Publication type:

Article

Whole genome and transcriptome profiling in advanced pancreatic cancer patients on the COMPASS trial.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60808-z

By:

Knox, Jennifer J.;
Jang, Gun Ho;
Grant, Robert C.;
Zhang, Amy;
Ma, Lucy;
Elimova, Elena;
Jang, Raymond;
Moore, Malcolm;
Biagi, James;
Tehfe, Mustapha;
Ramjeesingh, Ravi;
Tsang, Erica S.;
Holter, Spring;
Ramotar, Stephanie;
Hutchinson, Shawn;
Liang, Sheng-Ben;
Lungu, Ilinca M.;
Moura, Shari;
Wang, Yifan;
Perera, Sheron

Publication type:

Article

Orchestrating intratumoral DC-T cell immunity for enhanced tumor control via radiotherapy-activated TLR7/8 prodrugs in mice.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60769-3

By:

Yin, Xiaozhe;
Ding, Zexuan;
Yu, Li;
Zhang, Xuhao;
Gao, Yu;
Li, Yiyan;
Liu, Zhibo;
Fu, Yang-Xin

Publication type:

Article

Single-cell analysis reveals a longitudinal trajectory of meningioma evolution and heterogeneity.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60653-0

By:

Lee, Ji Yoon;
Lee, Eun Jung;
Seo, Bo Yeon;
Kim, Jiwon;
Song, Youjin;
Lee, Dayoung;
Moon, Namsung;
Koo, Harim;
Park, Chul-Kee;
Kim, Min-Sung;
Park, Serk In;
Nam, Do-Hyun;
Kong, Doo-Sik;
Sa, Jason K.

Publication type:

Article

The differential role of IL-33 and IL-38 in prostate cancer, contradictory roles.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1623038

By:

Ban, Runfen;
Gao, Shanshan;
Zhou, Bin;
Bao, Shisan

Publication type:

Article

Interplay between tumor cells and immune cells of the colorectal cancer tumor microenvironment: Wnt/β-catenin pathway.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1587950

By:

Janeeh, Aisha Saleh;
Bajbouj, Khuloud;
Rah, Bilal;
Abu-Gharbieh, Eman;
Hamad, Mawieh

Publication type:

Article

Recent advances in novel tumor immunotherapy strategies based on regulating the tumor microenvironment and immune checkpoints.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1529403

By:

Jing, Hanhui;
Gao, Yan;
Sun, Zongsheng;
Liu, Shanglong

Publication type:

Article

Tumor-associated macrophage-based predictive and prognostic model for hepatocellular carcinoma.

Published in:

PLoS ONE, 2025, v. 20, n. 7, p. 1, doi. 10.1371/journal.pone.0325120

By:

Shang, Changquan;
He, Tiancong;
Zhang, Yi

Publication type:

Article

Immune-checkpoint targeting drug conjugates: a novel class of promising therapeutic agents for cancer treatment.

Published in:

NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-01011-7

By:

Marchesi, Silvia;
Marinello, Arianna;
Ambrosini, Paolo;
Cavalli, Chiara;
Lo Russo, Giuseppe;
Occhipinti, Mario

Publication type:

Article

Analysis of an engineered organoid model of pancreatic cancer identifies hypoxia as a contributing factor in determining transcriptional subtypes.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-98344-x

By:

Landon-Brace, Natalie;
Latour, Simon;
Innes, Brendan T.;
Nurse, Michelle;
Cadavid, Jose L.;
Co, Ileana L.;
Tan, Cassidy M.;
Nowlan, Ferris;
Drissler, Sibil;
Notta, Faiyaz;
Jackson, Hartland Warren;
Bader, Gary D.;
McGuigan, Alison P.

Publication type:

Article

Prognostic impact of syndecan-1 expression and serum concentration in colorectal cancer.

Published in:

Oncology Letters, 2025, v. 30, n. 2, p. N.PAG, doi. 10.3892/ol.2025.15148

By:

Tawada, Kakeru;
Hayashi, Hirokatsu;
Endo, Masahide;
Horaguchi, Takeshi;
Yokoi, Ryoma;
Matsumoto, Keita;
Kuno, Masashi;
Fukada, Masahiro;
Asai, Ryuichi;
Sato, Yuta;
Yasufuku, Itaru;
Tajima, Jesse Yu;
Tanaka, Yoshihiro;
Takahashi, Takao;
Matsuhashi, Nobuhisa;
Tomita, Hiroyuki

Publication type:

Article

Propionate metabolism-related genes demonstrate the potential to serve as prognostic and immunotherapeutic markers in osteosarcoma.

Published in:

Oncology Letters, 2025, v. 30, n. 2, p. N.PAG, doi. 10.3892/ol.2025.15134

By:

Liu, Wei;
Xu, Ze;
Li, Mingdong;
Zhu, Nan;
Zhang, Shuo;
Zhang, Qilun;
Zhan, Junfeng

Publication type:

Article

Non-Animal Technologies to Study and Target the Tumour Vasculature and Angiogenesis.

Published in:

Organoids, 2025, v. 4, n. 2, p. 12, doi. 10.3390/organoids4020012

By:

Ferrero, Elisabetta;
Hue, Jonas;
Ferrarini, Marina;
Veschini, Lorenzo

Publication type:

Article

Tailoring of Albumin Nanoparticles Modified with Mannose for Effective Targeting in Immunosuppressive Tumor Microenvironment.

Published in:

Micro (2673-8023), 2025, v. 5, n. 2, p. 30, doi. 10.3390/micro5020030

By:

Kuznetsova, Alyona B.;
Gorbacheva, Valentina I.;
Kolesova, Ekaterina P.;
Egorova, Vera S.

Publication type:

Article

儿童及青少年甲状腺癌与桥本甲状腺炎的相关性.

Published in:

Journal of China Medical University, 2025, v. 54, n. 6, p. 481, doi. 10.12007/j.issn.0258‐4646.2025.06.001

By:

李新华;
王志宏;
张浩

Publication type:

Article

Enzyme-sensitive peptide KC26 modifies milk exosomes encapsulating carboplatin for the treatment of retinoblastoma.

Published in:

Pharmaceutical Development & Technology, 2025, v. 30, n. 5, p. 621, doi. 10.1080/10837450.2025.2505005

By:

Wang, Hetong;
Wang, Wei;
Tang, Qin;
Liu, Xun;
Zhu, Limin;
Sun, Di;
Lin, Tingting

Publication type:

Article

Spatial Transcriptomics Shows a Distinctive Tumour Microenvironment in the Invasive Versus Premalignant Portion of Early Cutaneous Squamous Cell Carcinoma.

Published in:

Experimental Dermatology, 2025, v. 34, n. 6, p. 1, doi. 10.1111/exd.70125

By:

Gim, Jeong‐An;
Kim, Chungyeul;
Oh, Hyun Jyung;
Kim, Ko Eun;
Jeon, Jiehyun;
Kim, Aeree;
Baek, Yoo Sang

Publication type:

Article

Low-density neutrophils: A critical component in understanding the tumor microenvironment of oral squamous cell carcinoma.

Published in:

Journal of Oral & Maxillofacial Pathology (0973029X), 2025, v. 29, n. 2, p. 172, doi. 10.4103/jomfp.jomfp_351_24

By:

Dineshkumar, Thayalan;
Anandan, Nirmala;
Krishnan, Rajkumar;
Nandhakumar, Indumathi

Publication type:

Article

Interplay of disulfidptosis and the tumor microenvironment across cancers: implications for prognosis and therapeutic responses.

Published in:

BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-025-14246-1

By:

Xu, Shengshan;
Chen, Zizhou;
Chen, Xiguang;
Chu, Hongyu;
Huang, Xufeng;
Chen, Chunyu;
Liu, Hejie;
Qu, Yuting;
Lu, Zhuming

Publication type:

Article

Metal Complexes Stimulating Immunogenic Pyroptosis as Burgeoning Antitumor Strategy.

Published in:

Angewandte Chemie, 2025, v. 137, n. 27, p. 1, doi. 10.1002/ange.202507186

By:

Zheng, Yue;
Peng, Kun;
Cao, Qian;
Mao, Zong‐Wan

Publication type:

Article

Single‐Atom W Anchored Hexagonal Boron Nitride Piezoelectric Nanosonosensitizer Remodels Tumor Microenvironment for Enhanced Sonodynamic Therapy.

Published in:

Advanced Functional Materials, 2025, v. 35, n. 26, p. 1, doi. 10.1002/adfm.202420974

By:

Deng, Hairui;
Li, Xianan;
Pan, Lingfeng;
Tang, Mengcheng;
Song, Pengyuan;
Long, Binghua;
Sun, Xu;
Li, Yao;
Zhang, Han;
Wang, Shibo;
Wang, Zhaojie;
Kong, Xiangdong

Publication type:

Article

Impact of tertiary lymphoid structure-associated biomarkers on pancreatic cancer via a dual-disease analysis of psoriasis and pancreatic cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03082-1

By:

Yu, Hao;
Yuan, Quan;
Feng, Liu-Xing;
Xu, Jia-Huan;
Zhan, Shen-Yuan;
Li, Zhi-min;
Wang, Shuang-Jia

Publication type:

Article

Clinical Impact of Serum CRP Levels on Advanced HCC Treated With Durvalumab and Tremelimumab: A Multicentre Study.

Published in:

Liver International, 2025, v. 45, n. 7, p. 1, doi. 10.1111/liv.70192

By:

Hatanaka, Takeshi;
Yata, Yutaka;
Hiraoka, Atsushi;
Tada, Toshifumi;
Hirooka, Masashi;
Kariyama, Kazuya;
Tani, Joji;
Atsukawa, Masanori;
Takaguchi, Koichi;
Itobayashi, Ei;
Kakizaki, Satoru;
Fukunishi, Shinya;
Tsuji, Kunihiko;
Ishikawa, Toru;
Tajiri, Kazuto;
Toyoda, Hidenori;
Koshiyama, Yuichi;
Ogawa, Chikara;
Nishikawa, Hiroki;
Nishimura, Takashi

Publication type:

Article

NKG7 is a Stable Marker of Cytotoxicity Across Immune Contexts and Within the Tumor Microenvironment.

Published in:

European Journal of Immunology, 2025, v. 55, n. 6, p. 1, doi. 10.1002/eji.202551885

By:

Turiello, Roberta;
Ng, Susanna S.;
Tan, Elisabeth;
van der Voort, Gemma;
Salim, Nazhifah;
Yong, Michelle C. R.;
Khassenova, Malika;
Oldenburg, Johannes;
Rühl, Heiko;
Hasenauer, Jan;
Surace, Laura;
Toma, Marieta;
Bald, Tobias;
Hölzel, Michael;
Corvino, Dillon

Publication type:

Article

Pro‐ and Anti‐Inflammatory Role of Complement in Cancer.

Published in:

European Journal of Immunology, 2025, v. 55, n. 6, p. 1, doi. 10.1002/eji.202451767

By:

Pal, Pradipta;
Wahi, Praneet;
Sahu, Arvind;
Lal, Girdhari

Publication type:

Article

Targeting tumor-associated macrophages in gastric cancer progression and therapy: insights from molecular mechanisms to therapeutic applications.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1549694

By:

Wan, ChengTao;
Deng, Jie;
Zhu, Yu;
Wan, Li;
Xu, Linyue;
Chen, Qiuyan;
Zou, Can;
Huang, Ju

Publication type:

Article

Therapeutic implications of cancer-associated fibroblast heterogeneity: insights from single-cell and multi-omics analysis.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1580315

By:

Wang, YuMin;
Ding, Yi;
Liu, HaoLin;
Xia, ZhongYou;
Liao, Guoqiang;
Fan, ShiCheng;
Li, JunXiong;
Qin, JingBo;
Liang, PinYao;
Gu, Peng;
Liu, XiaoDong;
Dong, RuNan

Publication type:

Article

The multifaceted role of microbiota in liver cancer: pathogenesis, therapy, prognosis, and immunotherapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1575963

By:

Feng, Yun;
Han, Meng-Zhen;
Zhou, Yu-Hang;
Wang, Yi-Wen;
Wang, Yue;
Sun, Tao;
Xu, Jun-Nan

Publication type:

Article

A Review of Silica-Based Nanoplatforms for Anticancer Cargo Delivery.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5850, doi. 10.3390/ijms26125850

By:

Mosseri, Andrea;
Sanchez-Uriel, Leticia;
Garcia-Peiro, Jose I.;
Hornos, Felipe;
Hueso, Jose L.

Publication type:

Article

Tumor Microenvironment, Inflammation, and Inflammatory Prognostic Indices in Diffuse Large B-Cell Lymphomas: A Narrative Review.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5670, doi. 10.3390/ijms26125670

By:

Cvetković, Zorica;
Marković, Olivera;
Marinković, Gligorije;
Pejić, Snežana;
Vučić, Vesna

Publication type:

Article

The Role of the Tumor Microenvironment in Gastroenteropancreatic Neuroendocrine Tumors.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5635, doi. 10.3390/ijms26125635

By:

Yellapragada, Srujana V.;
Forsythe, Steven D.;
Madigan, James P.;
Sadowski, Samira M.

Publication type:

Article

Adrenomedullin in Tumorigenesis and Cancer Progression.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5552, doi. 10.3390/ijms26125552

By:

Li, Hanyi;
Yang, Weijia;
Wang, Shiqi;
Zhao, Zhihe;
Wang, Wangyang;
Shi, Mingxuan;
Li, Yi

Publication type:

Article

Investigation of Anti-Cancer Properties of Nano-Encapsulated Ciprofloxacin Using 3D Cancer Cell Spheroids as Tumour Models.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5530, doi. 10.3390/ijms26125530

By:

Kabalan, Yasmin;
Matulewicz, Karolina;
Tylkowski, Bartosz;
Woźniak-Budych, Marta;
Staszak, Katarzyna;
Montané, Xavier;
Bajek, Anna

Publication type:

Article

Cell-Based Therapies for Solid Tumors: Challenges and Advances.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5524, doi. 10.3390/ijms26125524

By:

Smolarska, Anna;
Kokoszka, Zuzanna;
Naliwajko, Marcelina;
Strupczewska, Julia;
Tondera, Jędrzej;
Wiater, Maja;
Orzechowska, Roksana

Publication type:

Article