Works matching DE "STEROL regulatory element-binding proteins"

Results: 443

Integrative analysis of cholesterol homeostasis reveals prognostic subtypes and immune features in clear cell renal cell carcinoma.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03116-8

By:

Zhu, Jian;
Deng, Minghao;
Wang, Weizhuo;
Peng, Aijin;
Zhu, Anli;
Yang, Rongchao;
Jin, Zhenhua;
Zhang, Dong;
Zhang, Xi

Publication type:

Article

Localized delivery and retention of hydrogen sulfide causing regional lipid accumulation in mouse adipose tissues in vivo.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08353-9

By:

Verma, Richa;
Fu, Ming;
Arif, Hassan M.;
Yang, Guangdong;
Sarkar, Ishani;
Kaur, Kuljeet;
Matson, John B.;
Wu, Lingyun;
Wang, Rui

Publication type:

Article

SREBP-1 in obesity-induced breast cancer: mechanisms and therapeutic perspectives.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10775-x

By:

Tiwari, Urvashi;
Akhtar, Salman;
Mir, Snober S;
Khan, Mohammad Kalim Ahmad

Publication type:

Article

Editorial: Clinical Impact of Lipid Profile Change After DAA Treatment in CHC Patients—Authors' Reply.

Published in:

2025

By:

Sarrafan‐Chaharsoughi, Zahra;
Ghany, Marc G.

Publication type:

Editorial

Viral pathogenesis: Enabling HCV's need for fat.

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 7, p. 432, doi. 10.1038/nrmicro3054

By:

David, Rachel

Publication type:

Article

Monomethyl Branched-Chain Fatty Acids Play an Essential Role in Caenorhabditis elegans Development.

Published in:

PLoS Biology, 2004, v. 2, n. 8, p. 1, doi. 10.1371/journal.pbio.0020257

By:

Kniazeva, Marina;
Crawford, Quinn T;
Seiber, Matt;
Wang, Cun-Yu;
Han, Min

Publication type:

Article

PACS-2 deficiency in tubular cells aggravates lipid-related kidney injury in diabetic kidney disease.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00545-x

By:

Zhao, Chanyue;
Li, Li;
Li, Chenrui;
Tang, Chengyuan;
Cai, Juan;
Liu, Yu;
Yang, Jinfei;
Xi, Yiyun;
Yang, Ming;
Jiang, Na;
Han, Yachun;
Liu, Yan;
Luo, Shilu;
Xiao, Li;
Sun, Lin

Publication type:

Article

N‐arachidonoyl dopamine inhibits epithelial–mesenchymal transition of breast cancer cells through ERK signaling and decreasing the cellular cholesterol.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 4, p. 1, doi. 10.1002/jbt.22693

By:

Bandyopadhayaya, Shreetama;
Akimov, Mikhail G.;
Verma, Ranjeet;
Sharma, Ankit;
Sharma, Divya;
Kundu, Gopal C.;
Gretskaya, Natalia M.;
Bezuglov, Vladimir V.;
Mandal, Chandi C.

Publication type:

Article

Deregulation of hepatic lipid metabolism associated with insulin resistance in rats subjected to chronic monocrotophos exposure.

Published in:

Journal of Biochemical & Molecular Toxicology, 2020, v. 34, n. 8, p. 1, doi. 10.1002/jbt.22506

By:

Nagaraju, Raju;
Joshi, Apurva K. R.;
Vamadeva, Sowmya G.;
Rajini, Padmanabhan S.

Publication type:

Article

Global Collaborations in SREBP Research: Scientific Productivity and Impact.

Published in:

Mersin University School of Medicine Lokman Hekim Journal of History of Medicine & Folk Medicine, 2025, v. 15, n. 2, p. 739, doi. 10.31020/mutftd.1641269

By:

Antmeni, Şerife Efsun;
Yalaza, Cem

Publication type:

Article

Phosphatidic acid directly activates mTOR and then regulates SREBP to promote ganoderic acid biosynthesis under heat stress in Ganoderma lingzhi.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07225-y

By:

Liu, Yong-Nan;
Chen, Yu-Lin;
Zhang, Zi-Juan;
Wu, Feng-Yuan;
Wang, Hao-Jin;
Wang, Xiao-Ling;
Liu, Gao-Qiang

Publication type:

Article

Sorting (Nexin-13) out Novel Insights into Endolysosomal Cholesterol Export.

Published in:

Contact (25152564), 2022, v. 5, p. 1, doi. 10.1177/25152564221114513

By:

Lu, Albert

Publication type:

Article

Polyphenol-Rich Extracts from Toona sinensis Bark and Fruit Ameliorate Free Fatty Acid-Induced Lipogenesis through AMPK and LC3 Pathways.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 10, p. 1664, doi. 10.3390/jcm8101664

By:

Chen, Yung-Chia;
Chen, Hsin-Ju;
Huang, Bu-Miin;
Chen, Yu-Chi;
Chang, Chi-Fen

Publication type:

Article

Phyllanthus Urinaria Water Extract Ameliorates Lipid Accumulation and Oxidative Stress in Primary Chicken Hepatocytes.

Published in:

Journal of Animal Science, 2023, v. 101, p. 371, doi. 10.1093/jas/skad281.440

By:

Hsiao-Yin Lai;
Shih-Torng Ding

Publication type:

Article

Patatin-Like Phospholipase Domain-Containing Protein 3 Abundance is Affected by Knockdown of Sterol Regulatory Element-Binding Protein 1c but not of Carbohydrate Response Element Binding Protein.

Published in:

Journal of Animal Science, 2022, v. 100, p. 270, doi. 10.1093/jas/skac247.490

By:

Kendall, Sophia J.;
White, Heather M.

Publication type:

Article

Oleic acid in the absence of a PPARγ agonist increases adipogenic gene expression in bovine muscle satellite cells.

Published in:

Journal of Animal Science, 2019, v. 97, n. 10, p. 4114, doi. 10.1093/jas/skz269

By:

Li, Xiang Z;
Yan, Yan;
Zhang, Jun F;
Sun, Jian F;
Sun, Bin;
Yan, Chang G;
Choi, Seong H;
Johnson, Bradley J;
Kim, Jong K;
Smith, Stephen B

Publication type:

Article

Rapid communication: lipid metabolic gene expression and triacylglycerol accumulation in goat mammary epithelial cells are decreased by inhibition of <italic>SREBP-1</italic>.

Published in:

Journal of Animal Science, 2018, v. 96, n. 6, p. 2399, doi. 10.1093/jas/sky069

By:

Xu, Huifen;
Luo, Jun;
Tian, Huibin;
Li, Jun;
Zhang, Xueying;
Chen, Zhi;
Li, Ming;
Loor, Juan J

Publication type:

Article

TRIENNIAL LACTATION SYMPOSIUM: Nutrigenomics in dairy cows: Nutrients, transcription factors, and techniques.

Published in:

2015

By:

Bionaz, M.;
Osorio, J.;
Loor, J. J.

Publication type:

Conference Paper/Materials

Dietary Lycium barbarum Polysaccharide Modulates Growth Performance, Antioxidant Capacity, and Lipid Metabolism in Common Carp (Cyprinus carpio) Fed with High-Fat Diet.

Published in:

Antioxidants, 2024, v. 13, n. 5, p. 540, doi. 10.3390/antiox13050540

By:

Wu, Di;
Li, Jinnan;
Fan, Ze;
Sun, Zhipeng;
Zheng, Xianhu;
Zhang, Haitao;
Xu, Hong;
Wang, Liansheng

Publication type:

Article

Dietary Antioxidants and Chronic Diseases.

Published in:

2023

By:

Zujko, Małgorzata Elżbieta;
Witkowska, Anna Maria

Publication type:

Editorial

More Than an Antioxidant: Role of Dietary Astaxanthin on Lipid and Glucose Metabolism in the Liver of Rainbow Trout (Oncorhynchus mykiss).

Published in:

Antioxidants, 2023, v. 12, n. 1, p. 136, doi. 10.3390/antiox12010136

By:

Kalinowski, Carmen Tatiana;
Betancor, Monica B.;
Torrecillas, Silvia;
Sprague, Matthew;
Larroquet, Laurence;
Véron, Vincent;
Panserat, Stéphane;
Izquierdo, María Soledad;
Kaushik, Sadasivam J.;
Fontagné-Dicharry, Stéphanie

Publication type:

Article

Editorial: Diabetic kidney disease: routes to drug development, pharmacology and underlying molecular mechanisms, volume II.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1609100

By:

Bhatia, Divya;
Srivastava, Swayam Prakash

Publication type:

Article

Effects of celastrol on the heart and liver galaninergic system expression in a mouse model of Western-type diet-induced obesity and metabolic dysfunction-associated steatotic liver disease and steatohepatitis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1476994

By:

Canová, Nikolina;
Šípková, Jana;
Arora, Mahak;
Pavlíková, Zuzana;
Kučera, Tomáš;
Šeda, Ondřej;
Šopin, Tijana;
Vacík, Tomáš;
Slanař, Ondřej

Publication type:

Article

Elocalcitol, a fluorinated vitamin D derivative, prevents high-fat diet-induced obesity via SCAP downregulation and miR-146a-associated mechanisms.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2024.1505729

By:

Jürgenson, Monika;
Chithanathan, Keerthana;
Orav, Aivar;
Jaako, Külli;
Viil, Janeli;
Guha, Mithu;
Kask, Kalev;
Zharkovsky, Alexander

Publication type:

Article

Formononetin triggers ferroptosis in triple-negative breast cancer cells by regulating the mTORC1/SREBP1/SCD1 pathway.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1441105

By:

Xie, Dong;
Jiang, Yulang;
Wang, Huan;
Zhu, Lingyi;
Huang, Shuangqin;
Liu, Sheng;
Zhang, Weihong;
Li, Tian

Publication type:

Article

Formononetin triggers ferroptosis in triple-negative breast cancer cells by regulating the mTORC1/SREBP1/SCD1 pathway.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1441105

By:

Dong Xie;
Yulang Jiang;
Huan Wang;
Lingyi Zhu;
Shuangqin Huang;
Sheng Liu;
Weihong Zhang;
Tian Li

Publication type:

Article

Formononetin triggers ferroptosis in triple-negative breast cancer cells by regulating the mTORC1/SREBP1/SCD1 pathway.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1441105

By:

Dong Xie;
Yulang Jiang;
Huan Wang;
Lingyi Zhu;
Shuangqin Huang;
Sheng Liu;
Weihong Zhang;
Tian Li

Publication type:

Article

Cystatin from the helminth Ascaris lumbricoides upregulates mevalonate and cholesterol biosynthesis pathways and immunomodulatory genes in human monocyte-derived dendritic cells.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1328401

By:

Acevedo, Nathalie;
Lozano, Ana;
Zakzuk, Josefina;
Llinás-Caballero, Kevin;
Brodin, David;
Nejsum, Peter;
Williams, Andrew R.;
Caraballo, Luis

Publication type:

Article

Macrophage SREBP1 regulates skeletal muscle regeneration.

Published in:

Frontiers in Immunology, 2024, p. 01, doi. 10.3389/fimmu.2023.1251784

By:

Yumiko Oishi;
Hiroyuki Koike;
Naoki Kumagami;
Yoshimi Nakagawa;
Masaya Araki;
Yoshitaka Taketomi;
Yoshimi Miki;
Shigeru Matsuda;
Takashi Matsuzaka;
Hitoshi Ozawa;
Hitoshi Shimano;
Makoto Murakami;
Ichiro Manabe

Publication type:

Article

Hypoxia-altered cholesterol homeostasis enhances the expression of interferon-stimulated genes upon SARS-CoV-2 infections in monocytes.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1121864

By:

Bauer, Rebekka;
Meyer, Sofie Patrizia;
Raue, Rebecca;
Palmer, Megan A.;
Guerrero Ruiz, Vanesa Maria;
Cardamone, Giulia;
Rösser, Silvia;
Heffels, Milou;
Roesmann, Fabian;
Wilhelm, Alexander;
Lütjohann, Dieter;
Zarnack, Kathi;
Fuhrmann, Dominik Christian;
Widera, Marek;
Schmid, Tobias;
Brüne, Bernhard

Publication type:

Article

Sterol Regulatory Element-Binding Protein-1c Regulates Inflammasome Activation in Gingival Fibroblasts Infected with High-Glucose-Treated Porphyromonas gingivalis.

Published in:

Frontiers in Cellular & Infection Microbiology, 2016, v. 6, p. 1, doi. 10.3389/fcimb.2016.00195

By:

Hsing-Chun Kuo;
Li-Ching Chang;
Te-Chuan Chen;
Ko-Chao Lee;
Kam-Fai Lee;
Cheng-Nan Chen;
Hong-Ren Yu

Publication type:

Article

Ezetimibe increases intestinal expression of the LDL receptor gene in dyslipidaemic men with insulin resistance.

Published in:

Diabetes, Obesity & Metabolism, 2016, v. 18, n. 12, p. 1226, doi. 10.1111/dom.12749

By:

Drouin‐Chartier, Jean‐Philippe;
Tremblay, André J.;
Lemelin, Valéry;
Lépine, Marie‐Claude;
Lamarche, Benoît;
Couture, Patrick

Publication type:

Article

Cyclocarya paliurus modulates cholesterol metabolism in MASLD mice via upregulation of ABCG5/8 and SREBP2.

Published in:

Journal of Chinese Pharmaceutical Sciences, 2025, v. 34, n. 4, p. 305, doi. 10.5246/jcps.2025.04.023

By:

Xiaoai Bao;
Jiao Yan;
Xiaoyan Liu;
Yizheng Sun;
Hailong Xu;
Rong Han;
Haitao Zhu;
Gaigai Deng;
Youbo Zhang

Publication type:

Article

Bioactive fraction from Lagerstroemia speciosa leaves (DLBS3733) reduces fat droplet by inhibiting adipogenesis and lipogenesis.

Published in:

Journal of Experimental Pharmacology, 2019, v. 11, p. 39, doi. 10.2147/JEP.S181642

By:

Karsono, Agung Heru;
Tandrasasmita, Olivia Mayasari;
Tjandrawinata, Raymond Rubianto

Publication type:

Article

Copy number amplification of FLAD1 promotes the progression of triple-negative breast cancer through lipid metabolism.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56458-w

By:

Song, Xiao-Qing;
Yu, Tian-Jian;
Ou-Yang, Yang;
Ding, Jia-Han;
Jiang, Yi-Zhou;
Shao, Zhi-Ming;
Xiao, Yi

Publication type:

Article

High mobility group A1 (HMGA1) promotes the tumorigenesis of colorectal cancer by increasing lipid synthesis.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-54400-0

By:

Zhao, Yuan;
Liu, Meng-Jie;
Zhang, Lei;
Yang, Qi;
Sun, Qian-Hui;
Guo, Jin-Rong;
Lei, Xin-Yuan;
He, Kai-Yue;
Li, Jun-Qi;
Yang, Jing-Yu;
Jian, Yong-Ping;
Xu, Zhi-Xiang

Publication type:

Article

Phloretin ameliorates hepatic steatosis through regulation of lipogenesis and Sirt1/AMPK signaling in obese mice.

Published in:

Cell & Bioscience, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13578-020-00477-1

By:

Liou, Chian-Jiun;
Wu, Shu-Ju;
Shen, Szu-Chuan;
Chen, Li-Chen;
Chen, Ya-Ling;
Huang, Wen-Chung

Publication type:

Article

Dysregulation of the SREBP pathway is associated with poor prognosis and serves as a potential biomarker for the diagnosis of hepatocellular carcinoma.

Published in:

Molecular Medicine Reports, 2025, v. 31, n. 5, p. N.PAG, doi. 10.3892/mmr.2025.13477

By:

Li, Xiaodan;
Wang, Yuhan;
Liu, Junchi;
Gao, Tianmiao;
Cao, Lizhi;
Yan, Meng;
Li, Na

Publication type:

Article

FBXW7 mediates high glucose-induced SREBP-1 expression in renal tubular cells of diabetic nephropathy under PI3K/Akt pathway regulation.

Published in:

Molecular Medicine Reports, 2021, v. 23, n. 4, p. N.PAG, doi. 10.3892/mmr.2021.11872

By:

Li, Lisha;
Yang, Juxiang;
Li, Fan;
Gao, Fan;
Zhu, Lin;
Hao, Jun

Publication type:

Article

SREBP2 is upregulated in esophageal squamous cell carcinoma and co-operates with c-Myc to regulate HMGCR expression.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3003, doi. 10.3892/mmr.2019.10577

By:

Zhong, Chenxi;
Fan, Limin;
Li, Zhigang;
Yao, Feng;
Zhao, Heng

Publication type:

Article

LRG ameliorates steatohepatitis by activating the AMPK/mTOR/SREBP1 signaling pathway in C57BL/6J mice fed a high-fat diet.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 1, p. 701, doi. 10.3892/mmr.2019.10304

By:

Hao, Tao;
Chen, Hongying;
Wu, Sisi;
Tian, Haoming

Publication type:

Article

Association of SREBP2 gene polymorphisms with the risk of osteonecrosis of the femoral head relates to gene expression and lipid metabolism disorders.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 5, p. 7145, doi. 10.3892/mmr.2017.7473

By:

YANG SONG;
BINGPENG CHEN;
MING REN;
QINGYU WANG;
AO WANG;
YANGUO QIN;
ZHENWU DU;
QIWEI YANG;
GUIZHEN ZHANG;
YUJIE SUI;
HAIYUE ZHAO

Publication type:

Article

Berberine activates AMPK to suppress proteolytic processing, nuclear translocation and target DNA binding of SREBP-1c in 3T3-L1 adipocytes.

Published in:

Molecular Medicine Reports, 2017, v. 15, n. 6, p. 4139, doi. 10.3892/mmr.2017.6513

By:

JAEWOONG JANG;
YOONJU JUNG;
SANG‑IN CHUNG;
YOOSIK YOON;
SEONG JUN SEO;
SEOK‑MIN KIM;
YAE JIE SHIM;
SOO HYUN CHO

Publication type:

Article

Flavonoids from Triticum aestivum inhibit adipogenesis in 3T3-L1 cells by upregulating the insig pathway.

Published in:

Molecular Medicine Reports, 2015, v. 12, n. 2, p. 3139, doi. 10.3892/mmr.2015.3700

By:

BARUN POUDEL;
SARMILA NEPALI;
MINGJIE XIN;
HYEON-HUI KI;
YOUNG-HO KIM;
DAE-KI KIM;
YOUNG-MI LEE

Publication type:

Article

The inhibition of oleic acid induced hepatic lipogenesis and the promotion of lipolysis by caffeic acid via up-regulation of AMP-activated kinase.

Published in:

Journal of the Science of Food & Agriculture, 2014, v. 94, n. 6, p. 1154, doi. 10.1002/jsfa.6386

By:

Liao, Chung‐Chia;
Ou, Ting‐Tsz;
Huang, Hui‐Pei;
Wang, Chau‐Jong

Publication type:

Article

Inhibition of Proprotein Convertase Subtilisin/Kexin Type 9 Ameliorates Liver Fibrosis via Mitigation of Intestinal Endotoxemia.

Published in:

Inflammation, 2020, v. 43, n. 1, p. 251, doi. 10.1007/s10753-019-01114-x

By:

Zou, Yanting;
Li, Shuyu;
Xu, Beili;
Guo, Hongying;
Zhang, Shuncai;
Cai, Yu

Publication type:

Article

TMAO is involved in sleep deprivation-induced cognitive dysfunction through regulating astrocytic cholesterol metabolism via SREBP2.

Published in:

Frontiers in Molecular Neuroscience, 2024, p. 1, doi. 10.3389/fnmol.2024.1499591

By:

Zhu, Shan;
Wang, Yue;
Li, Yansong;
Li, Na;
Zheng, Yige;
Li, Qiao;
Guo, Hongyan;
Sun, Jianyu;
Zhai, Qian;
Zhu, Yaomin

Publication type:

Article

Editorial: Editors' showcase: molecular signalling and pathways.

Published in:

Frontiers in Molecular Neuroscience, 2024, p. 1, doi. 10.3389/fnmol.2024.1479278

By:

Taymans, Jean-Marc;
Yilmazer-Hanke, Deniz

Publication type:

Article

Minocycline suppresses lipogenesis via inhibition of p300 histone acetyltransferase activity in human SZ95 sebocytes.

Published in:

Journal of the European Academy of Dermatology & Venereology, 2022, v. 36, n. 8, p. 1325, doi. 10.1111/jdv.18079

By:

Shin, H.S.;
Zouboulis, C.C.;
Kim, M.K.;
Lee, D.H.;
Chung, J.H.

Publication type:

Article

mTOR regulates fatty infiltration through SREBP-1 and PPARγ after a combined massive rotator cuff tear and suprascapular nerve injury in rats.

Published in:

Journal of Orthopaedic Research, 2013, v. 31, n. 5, p. 724, doi. 10.1002/jor.22254

By:

Joshi, Sunil K.;
Liu, Xuhui;
Samagh, Sanjum P.;
Lovett, David H.;
Bodine, Sue C.;
Kim, Hubert T.;
Feeley, Brian T.

Publication type:

Article