Works matching DE "SOMATIC mutation"

Results: 3913

Regional profiling reveals a distinct glioblastoma infiltrative margin proteome.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-09228-z

By:

Kocon, Artur;
Smith, Stuart J.;
Morentin, Benito;
Callado, Luis F.;
Carter, Wayne;
Rahman, Ruman

Publication type:

Article

Selective targeting of the AKT1 (E17K) mutation: advances in precision oncology and therapeutic design.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03083-0

By:

Chen, Xiaoyan;
Zhang, Danfeng;
Xue, Jiapeng;
Li, Zhi

Publication type:

Article

Multigene Analysis in Women with Precancerous Conditions of The Endometrium and in Patients with Endometrial Carcinoma.

Published in:

Bratislava Medical Journal / Bratislavské Lekárske Listy, 2025, v. 126, n. 7, p. 1381, doi. 10.1007/s44411-025-00155-z

By:

Kodada, Dominik;
Gergely, Lajos;
Krumpolec, Patrik;
Janoštiaková, Nikola;
Bľandová, Gabriela;
Janega, Pavol;
Minárik, Gabriel;
Repiská, Vanda

Publication type:

Article

Joint inference of mutational signatures from indels and single-nucleotide substitutions reveals prognostic impact of DNA repair deficiencies.

Published in:

Genome Medicine, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13073-025-01497-7

By:

Ferrer-Torres, Patricia;
Galván-Femenía, Iván;
Supek, Fran

Publication type:

Article

Comparable outcomes with 14-, 21-, or standard 28-day venetoclax in the first cycle of azacitidine–venetoclax in untreated acute myeloid leukemia: real-world experience from the Hokkaido Leukemia Net.

Published in:

Blood Cancer Journal, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41408-025-01324-7

By:

Kanaya, Minoru;
Onozawa, Masahiro;
Matsukawa, Toshihiro;
Miyashita, Naoki;
Fujii, Fumiaki;
Yoshida, Shota;
Nagai, Jun;
Aiba, Masayuki;
Hidaka, Daisuke;
Hashiguchi, Junichi;
Senjo, Hajime;
Igarashi, Tetsuyuki;
Chiba, Masahiro;
Yamamoto, Satoshi;
Shimizu, Taku;
Ishio, Takashi;
Yokoyama, Shota;
Ebata, Ko;
Iyama, Satoshi;
Oyake, Tatsuo

Publication type:

Article

Investigating the genetic landscape of cancer in Jordan: a step toward personalized care.

Published in:

European Journal of Medical Research, 2025, v. 30, n. 1, p. 1, doi. 10.1186/s40001-025-02799-7

By:

AL-Eitan, Laith N.;
Tarkhan, Amneh H.;
Ali, Haneen O.;
Alasmar, Maryam K.;
Alghamdi, Mansour A.

Publication type:

Article

Deep sequencing of circulating tumour DNA as a biomarker of clinical outcome to transarterial chemoembolisation in hepatocellular carcinoma.

Published in:

NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-00961-2

By:

Sharma, Rohini;
Alharbi, Sultan N.;
Ellum, Ksenia;
Motedayen-Aval, Leila;
Casadei-Gardini, Andrea;
Pinato, David J.;
Bettinger, Dominik;
Bengsch, Bertram;
Patel, Rishi;
Evans, Joanne

Publication type:

Article

Integrating gene mutation spectra from tumors and the general population with gene expression topological networks to identify novel cancer driver genes.

Published in:

Human Genetics, 2025, v. 144, n. 7, p. 775, doi. 10.1007/s00439-025-02755-9

By:

Yang, Shuangyu;
He, Dan;
Li, Ling;
Lu, Zhiya;
Li, Shaoying;
Lan, Tianjun;
Liu, Feiyi;
Zhang, Huasong;
Cooper, David N.;
Zhao, Huiying

Publication type:

Article

Clinical relevance of the somatic mutational landscaping in predicting outcome of bladder cancer patients.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-04363-z

By:

Nedjadi, Taoufik;
Ansari, Hifzur;
Khan, Muhammad A.;
Sannan, Naif;
Al-Mansour, Mubarak;
Al-Maghrabi, Jaudah;
Dallol, Ashraf

Publication type:

Article

The Impact of Ordinary and Partial Differential Equations in Understanding Brain Cancer Progression and Improving Treatments: A Decade-long Study.

Published in:

IAENG International Journal of Applied Mathematics, 2025, v. 55, n. 7, p. 1991

By:

Divya, T.;
Ananthan, V.

Publication type:

Article

Clinical Outcome and Molecular Profile in Patients with DDX41 Mutation Hot-Spots.

Published in:

Hematology Reports, 2025, v. 17, n. 3, p. 26, doi. 10.3390/hematolrep17030026

By:

Toumeh, Nadia;
Jabban, Yazan;
Nanaa, Ahmad;
He, Rong;
Viswanatha, David;
Jevremovic, Dragan;
Foran, James M.;
Arana Yi, Cecilia Y.;
Saliba, Antoine N.;
Hefazi Torghabeh, Mehrdad;
Hogan, William J.;
Shah, Mithun V.;
Mangaonkar, Abhishek A.;
Patnaik, Mrinal M.;
Alkhateeb, Hassan B.;
Al-Kali, Aref

Publication type:

Article

Comparison of somatic mutations and clinicopathologic features of micropapillary and non-micropapillary colorectal carcinomas.

Published in:

BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-025-14487-0

By:

Sagnak Yilmaz, Zeynep;
Demir Kececi, Sibel;
Aydin Mungan, Sevdegul;
Saygin, Ismail;
Sarioglu, Sulen

Publication type:

Article

Integrated bulk and single-cell RNA sequencing reveals a cuproptosis-related LncRNA prognostic signature in neuroblastoma.

Published in:

BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-025-14463-8

By:

Chen, Ke;
Wang, Jing;
Yang, Shimin;
Xiao, Jun;
Wu, Luyao;
Li, Zejian;
Zhao, Xiang;
Chen, Xuyong;
Li, Honglin;
Feng, Jiexiong;
Meng, Xinyao

Publication type:

Article

Landscape of cancer associated EpCAM mutations: molecular modeling, predictive insights and impact on patient survival.

Published in:

BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-025-14455-8

By:

Dhotare, Priyanka S.;
Bochi-Layec, Audrey C.;
Fleming, Timothy P.;
Gillanders, William E.;
Bremner, Ross M.;
Sonawane, Kailas D.;
Sankpal, Narendra V.

Publication type:

Article

Do Colorectal Serrated and Non-Serrated Adenocarcinomas Differ in Somatic Mutations and Clinicopathologic Features?

Published in:

Medicina (1010660X), 2025, v. 61, n. 6, p. 1032, doi. 10.3390/medicina61061032

By:

Sagnak Yilmaz, Zeynep;
Demir Kececi, Sibel;
Aydin Mungan, Sevdegul;
Saygin, Ismail;
Sagol, Ozgul;
Sarioglu, Sulen

Publication type:

Article

SNP-based molecular diagnostic platform: rapid single-step identification of Theileria annulata and its buparvaquone-resistant strains.

Published in:

Parasites & Vectors, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13071-025-06884-y

By:

Che, Jin;
Chai, Yijun;
Zhao, Shuaiyang;
Wang, Jinming;
Luo, Jianxun;
Guan, Guiquan;
Yin, Hong;
Li, Wei

Publication type:

Article

Genetic analysis in patients with newly diagnosed glioblastomas treated with interferon-beta plus temozolomide in comparison with temozolomide alone.

Published in:

Journal of Neuro-Oncology, 2020, v. 148, n. 1, p. 17, doi. 10.1007/s11060-020-03505-9

By:

Natsume, Atsushi;
Aoki, Kosuke;
Ohka, Fumiharu;
Maeda, Sachi;
Hirano, Masaki;
Adilijiang, Alimu;
Motomura, Kazuya;
Sumi, Minako;
Nishikawa, Ryo;
Narita, Yoshitaka;
Muragaki, Yoshihiro;
Maruyama, Takashi;
Ito, Tamio;
Beppu, Takaaki;
Nakamura, Hideo;
Kayama, Takamasa;
Sato, Shinya;
Nagane, Motoo;
Mishima, Kazuhiko;
Nakasu, Yoko

Publication type:

Article

Targetable molecular alterations in congenital glioblastoma.

Published in:

Journal of Neuro-Oncology, 2020, v. 146, n. 2, p. 247, doi. 10.1007/s11060-019-03377-8

By:

Gilani, Ahmed;
Donson, Andrew;
Davies, Kurtis D.;
Whiteway, Susan L.;
Lake, Jessica;
DeSisto, John;
Hoffman, Lindsey;
Foreman, Nicholas K.;
Kleinschmidt-DeMasters, B. K.;
Green, Adam L.

Publication type:

Article

A cancer tissue-specific FAM72 expression profile defines a novel glioblastoma multiform (GBM) gene-mutation signature.

Published in:

Journal of Neuro-Oncology, 2019, v. 141, n. 1, p. 57, doi. 10.1007/s11060-018-03029-3

By:

Rahane, Chinmay Satish;
Kutzner, Arne;
Heese, Klaus

Publication type:

Article

Double somatic <italic>SMARCB1</italic> and <italic>NF2</italic> mutations in sporadic spinal schwannoma.

Published in:

Journal of Neuro-Oncology, 2018, v. 137, n. 1, p. 33, doi. 10.1007/s11060-017-2711-6

By:

Paganini, Irene;
Capone, Gabriele Lorenzo;
Vitte, Jeremie;
Sestini, Roberta;
Putignano, Anna Laura;
Giovannini, Marco;
Papi, Laura

Publication type:

Article

Tumor-specific mutations in low-frequency genes affect their functional properties.

Published in:

Journal of Neuro-Oncology, 2015, v. 122, n. 3, p. 461, doi. 10.1007/s11060-015-1741-1

By:

Erdem-Eraslan, Lale;
Heijsman, Daphne;
Wit, Maurice;
Kremer, Andreas;
Sacchetti, Andrea;
Spek, Peter;
Smitt, Peter;
French, Pim

Publication type:

Article

Epidemiology and etiopathogenesis of pituitary adenomas.

Published in:

Journal of Neuro-Oncology, 2014, v. 117, n. 3, p. 379, doi. 10.1007/s11060-013-1354-5

By:

Aflorei, Elena;
Korbonits, Márta

Publication type:

Article

The Impact of SARS-CoV-2 Omicron Mutations on the Conformational Landscape of the Spike Protein.

Published in:

Microscopy & Microanalysis, 2024, v. 30, p. 1, doi. 10.1093/mam/ozae044.412

By:

Parsons, Ruth J;
Calloway, Alexandria;
Zhang, Ellie;
Thakur, Bhishem;
Janowska, Katarzyna;
Acharya, Priyamvada

Publication type:

Article

Role of immune related genes in predicting prognosis and immune response in patients with hepatocellular carcinoma.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 1, p. 1, doi. 10.1002/jbt.23519

By:

Chen, Yi;
Shen, Chuchen;
Wu, Juju;
Yan, Xiaodan;
Huang, Qin

Publication type:

Article

Allogenic haematopoietic stem cell transplantation in VEXAS: A review of 33 patients.

Published in:

Clinical Rheumatology, 2024, v. 43, n. 11, p. 3565, doi. 10.1007/s10067-024-07160-7

By:

Ali, Syed B.;
Gurnari, Carmelo

Publication type:

Article

A novel method for isolating lymphatic endothelial cells from lymphatic malformations and detecting PIK3CA somatic mutation in these isolated cells.

Published in:

Surgery Today, 2021, v. 51, n. 3, p. 439, doi. 10.1007/s00595-020-02122-3

By:

Usui, Hidehito;
Tsurusaki, Yoshinori;
Shimbo, Hiroko;
Saitsu, Hirotomo;
Harada, Noriaki;
Kitagawa, Norihiko;
Mochizuki, Kyoko;
Masuda, Munetaka;
Kurosawa, Kenji;
Shinkai, Masato

Publication type:

Article

Long-term survival in patients with IDH-wildtype glioblastoma: clinical and molecular characteristics.

Published in:

Acta Neurochirurgica, 2023, v. 165, n. 4, p. 1075, doi. 10.1007/s00701-023-05544-3

By:

Chehade, Georges;
Lawson, Tévi Morel;
Lelotte, Julie;
Daoud, Lina;
Di Perri, Dario;
Whenham, Nicolas;
Duprez, Thierry;
Tajeddine, Nicolas;
Tissir, Fadel;
Raftopoulos, Christian

Publication type:

Article

Sporadic Parathyroid Carcinoma Treated With Lenvatinib, Exhibiting a Novel Somatic MEN1 Mutation.

Published in:

JCEM Case Reports, 2024, v. 2, n. 8, p. 1, doi. 10.1210/jcemcr/luae121

By:

Yu Ito;
Toshinori Imaizumi;
Hisashi Daido;
Takehiro Kato;
Daisuke Yabe

Publication type:

Article

Shared chromatin remodeling mutations drive concurrent rhabdomyosarcoma and leukemia in a pediatric patient.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02967-5

By:

Zhao, Ji'ou;
Li, Huimin;
Wang, Yongren;
Sun, Xiaoyan;
Fang, Yongjun;
Xue, Yao

Publication type:

Article

Deciphering the interaction between the expression of LRP2 served as a mitochondrial metabolism-related gene and prognosis in colon cancer integrating multi-omics analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02568-2

By:

Zhang, Jie;
Liu, Ziyun;
Ma, Xiaoqing;
Shi, Zhenyu;
Zhao, Jing;
Xie, Yongjie;
Shang, Xiaobin;
Zhang, Xia

Publication type:

Article

Exploring the potential role of ADRB1 as a tumor suppressor gene and prognostic biomarker in pan-cancer analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02460-z

By:

Xu, Shenghan;
Wang, Xinlei;
Wang, Yani;
Liu, Min;
Chen, Hao

Publication type:

Article

Global trends and research status in clonal hematopoiesis: a bibliometric analysis of the last 10 years.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02517-z

By:

Luo, QingQing;
Yu, Li

Publication type:

Article

FOXM1 could serve as a bridge mediating prognosis and immunity for clear cell renal cell carcinoma via single-cell and bulk RNA-sequencing.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02438-x

By:

Zhou, Jianhua;
Xu, Zhuxian;
Yu, Yang;
Zhu, Bingye;
Xing, Qianwei

Publication type:

Article

Thyroid hormone receptor interacting protein 13 is associated with prognosis and immunotherapy efficacy in human cancers: a pan-cancer analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02385-7

By:

Zheng, ShengYao;
Wang, HongYi;
Wang, Yingyi

Publication type:

Article

Utilizing multi-omics analysis, a new signature has been identified and validated for predicting prognosis and response to immunotherapy in lung squamous cell carcinoma, which is based on tumor mutation burden.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02166-2

By:

Wang, Dongguang;
Wang, Yan;
Peng, Yiqun;
Peng, Liang

Publication type:

Article

Multi-omics analysis identifies DLX4 as a novel biomarker for diagnosis, prognosis, and immune infiltration: from pan-cancer to renal cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02258-z

By:

Kou, Zengshun;
Zhu, Shuaizhi;
Zhu, Jiaxi;
Wang, Shufei;
Zheng, Yu;
Zhou, Shengjie;
Si, Zi'ang;
Zhu, Hai

Publication type:

Article

Integrative analysis and prognostication in gastric cancer: unveiling the role of mitochondrial genomics with the MLRScore model.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02203-0

By:

Wen, Yiru;
Chen, Peng;
Wang, Yong;
Lu, Chunyan;
Li, Cao;
Peng, Liu;
Cheng, Xiaohong;
Guo, Yulan;
Quan, Jun;
Wen, Yue;
Yang, Lie

Publication type:

Article

Identification of PANoptosis associated lncRNAs associated with clinical prognosis and immune infiltration microenvironment in colon adenocarcinoma.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01838-3

By:

Wang, Yangyang;
Zhao, Shihui;
Du, Songtao;
Xia, Tianyi;
Song, Liqiang;
Xia, Mingyu;
Zhang, Bomiao

Publication type:

Article

The T cell-mediated tumor killing patterns revealed tumor heterogeneous and proposed treatment recommendation in ovary cancer.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01635-4

By:

Wen, Xinglin;
Yin, Beining;
Lin, Li;
Liu, Long;
Weng, Siyuan;
Xu, Hui;
Zhang, Yuyuan;
Deng, Jinhai;
Liao, Ruiying;
Fan, Cungeng

Publication type:

Article

Discovery of Novel and Potent Inhibitors Against Mutational Variants of IDH1 Protein for Glioma Therapy: A Fragment-Based Approach.

Published in:

Journal of Computational Biophysics & Chemistry, 2023, v. 22, n. 1, p. 43, doi. 10.1142/S2737416523500023

By:

Murali, Poornimaa;
Karuppasamy, Ramanathan

Publication type:

Article

Different Clinical Presentations of Monogenic Vexas Syndrome.

Published in:

Türkiye Klinikleri Journal of Case Reports, 2024, v. 32, n. 1, p. 10, doi. 10.5336/caserep.2024-101256

By:

KARADENİZ, Mine;
MALKAN, Ümit Yavuz;
BÜYÜKAŞIK, Yahya

Publication type:

Article

Diagnostics and treatment of BRCA-associated cancers with olaparib -- expert position statement.

Published in:

Oncology in Clinical Practice (2450-1654), 2024, v. 20, n. 4, p. 229, doi. 10.5603/ocp.99216

By:

Kowalik, Artur;
Chudecka-Głaz, Anita;
Kufel-Grabowska, Joanna;
Skoneczna, Iwona;
Kubiatowski, Tomasz

Publication type:

Article

Papillary Renal Cell Carcinoma: Demographics, Survival Analysis, Racial Disparities, and Genomic Landscape.

Published in:

Journal of Kidney Cancer & VHL, 2023, v. 10, n. 4, p. 33, doi. 10.15586/jkcvhl.v10i4.294

By:

Ullah, Asad;
Khan Yasinzai, Abdul Qahar;
Daino, Naema;
Tareen, Bisma;
Jogezai, Zulfiqar Haider;
Sadia, Haleema;
Jamil, Nimra;
Baloch, Girahnaz;
Karim, Adil;
Badini, Kaleemullah;
Wali, Agha;
Waheed, Abdul;
Khan, Marjan;
Asif, Bina;
Kakar, Kaleemullah;
Heneidi, Saleh;
Sidhwa, Feroze;
Karki, Nabin R.

Publication type:

Article

Super-enhancers orchestrate transcriptional dysregulation and metabolic reprogramming in uveal melanoma.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08338-8

By:

Pan, Hui;
Shao, Weihuan;
Wang, Huixue;
Ge, Shengfang;
Zhang, Lingyu;
Xu, Xiaofang;
Wang, Yefei;
Zhuang, Ai

Publication type:

Article

Characterizing somatic mutations in ovarian cancer germline risk regions.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08072-1

By:

Lai, Ping-Hung;
Tyrer, Jonathan P.;
Pharoah, Paul;
Gayther, Simon A.;
Jones, Michelle R.;
Peng, Pei-Chen

Publication type:

Article

Comprehensive genomic dependency landscape of a human colon cancer organoid.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07822-5

By:

Khalili, Sana;
Mohseninia, Atefeh;
Liu, Changlong;
Banister, Carolyn E.;
Heine, Paige;
Khazan, Minou;
Morrison, Sidney E.;
Gokare, Prashanth;
Cowley, Glenn S.;
Weir, Barbara A.;
Pocalyko, David;
Bachman, Kurtis E.;
Buckhaults, Phillip J.

Publication type:

Article

Comprehensive genomic dependency landscape of a human colon cancer organoid.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07822-5

By:

Khalili, Sana;
Mohseninia, Atefeh;
Liu, Changlong;
Banister, Carolyn E.;
Heine, Paige;
Khazan, Minou;
Morrison, Sidney E.;
Gokare, Prashanth;
Cowley, Glenn S.;
Weir, Barbara A.;
Pocalyko, David;
Bachman, Kurtis E.;
Buckhaults, Phillip J.

Publication type:

Article

Defective X-chromosome inactivation and cancer risk in women.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07691-y

By:

Cáceres, Alejandro;
Pérez-Jurado, Luis A.;
Alegret-García, Albert;
Dwaraka, Varun B.;
Smith, Ryan;
González, Juan R.

Publication type:

Article

Single-cell somatic copy number variants in brain using different amplification methods and reference genomes.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06940-w

By:

Kalef-Ezra, Ester;
Turan, Zeliha Gozde;
Perez-Rodriguez, Diego;
Bomann, Ida;
Behera, Sairam;
Morley, Caoimhe;
Scholz, Sonja W.;
Jaunmuktane, Zane;
Demeulemeester, Jonas;
Sedlazeck, Fritz J.;
Proukakis, Christos

Publication type:

Article

Genetic and Epigenetic Study of Monozygotic Twins Affected by Parkinson's Disease.

Published in:

Clinical & Translational Neuroscience, 2023, v. 7, n. 2, p. 1, doi. 10.3390/ctn7020011

By:

Yi-Min Sun;
Wan-Li Yang;
Rogaeva, Ekaterina;
Lang, Anthony E.;
Jian Wang;
Ming Zhang

Publication type:

Article