Works about SMALL molecules
Results: 5000
Recent advances in small molecule LpxC inhibitors against gram-negative bacteria (2014–2024).
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- Frontiers in Microbiology, 2025, p. 1, doi. 10.3389/fmicb.2025.1541379
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Predicting transcriptional changes induced by molecules with MiTCP.
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- Briefings in Bioinformatics, 2025, v. 26, n. 1, p. 1, doi. 10.1093/bib/bbaf006
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In-depth profile of biosignatures for T2DM cohort utilizing an integrated targeted LC-MS platform.
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- Scientific Data, 2025, v. 12, n. 1, p. 1, doi. 10.1038/s41597-025-04652-2
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Computational study on the mechanism of small molecules inhibiting NLRP3 with ensemble docking and molecular dynamic simulations.
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- BMC Pharmacology & Toxicology, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s40360-025-00851-0
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The Effects of Naturally Occurring Phenols on Amyloid Fibrils from Insulin in the Liquid Phase Using Atomic Force Microscopy.
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- Natural Product Communications, 2025, v. 20, n. 2, p. 1, doi. 10.1177/1934578X241306603
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An abundant ginger compound furanodienone alleviates gut inflammation via the xenobiotic nuclear receptor PXR in mice.
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- Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56624-0
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Effect of Methyl Glycoside on Apoptosis and Oxidative Stress in Hypoxia Induced-Reoxygenated H9C2 Cell Lines.
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- Cell Biochemistry & Biophysics, 2025, v. 83, n. 1, p. 1045, doi. 10.1007/s12013-024-01539-8
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Molecular glues of the regulatory ChREBP/14-3-3 complex protect beta cells from glucolipotoxicity.
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- Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-57241-7
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Discoidin domain receptor inhibitor DDR1-IN-1 induces autophagy and necroptotic cell death in malignant peripheral nerve sheath tumor.
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- Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02367-2
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Review on activation of small molecules (dihydrogen, carbon dioxide, and dinitrogen) by various transition metal complexes.
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- Journal of Chemical Research, 2025, v. 49, n. 1, p. 1, doi. 10.1177/17475198251313648
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- Article
Zebularine showed anti-tumor efficacy in clear cell renal cell carcinoma.
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- Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1531056
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An update on the molecular mechanisms underlying the progression of miR-21 in oral cancer.
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- World Journal of Surgical Oncology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12957-025-03732-2
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- Article
Effects of c-Kit Receptor, AKT, and NF-κB Inhibitors on Immune Evasion in Multiple Myeloma Cells.
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- Iranian Journal of Allergy, Asthma & Immunology, 2025, v. 24, n. 1, p. 89, doi. 10.18502/ijaai.v24i1.18024
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From Genetics to Neuroinflammation: The Impact of ApoE4 on Microglial Function in Alzheimer's Disease.
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- Cells (2073-4409), 2025, v. 14, n. 4, p. 243, doi. 10.3390/cells14040243
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Ubiquitin-Specific Protease Inhibitors for Cancer Therapy: Recent Advances and Future Prospects.
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- Biomolecules (2218-273X), 2025, v. 15, n. 2, p. 240, doi. 10.3390/biom15020240
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- Article
Dual Therapy in Inflammatory Bowel Disease.
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- Biomolecules (2218-273X), 2025, v. 15, n. 2, p. 222, doi. 10.3390/biom15020222
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Subcellular Organelle Targeting as a Novel Approach to Combat Tumor Metastasis.
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- Pharmaceutics, 2025, v. 17, n. 2, p. 198, doi. 10.3390/pharmaceutics17020198
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- Article
Fluorescent Probes to Image the K Ca 3.1 Channel in Tumor Cells.
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- Pharmaceutics, 2025, v. 17, n. 2, p. 154, doi. 10.3390/pharmaceutics17020154
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- Article
Discovery of Biofilm-Inhibiting Compounds to Enhance Antibiotic Effectiveness Against M. abscessus Infections.
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- Pharmaceuticals (14248247), 2025, v. 18, n. 2, p. 225, doi. 10.3390/ph18020225
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Drug Development in Inflammatory Bowel Diseases: What Is Next?
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- Pharmaceuticals (14248247), 2025, v. 18, n. 2, p. 190, doi. 10.3390/ph18020190
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Dry Powder Inhalers for Delivery of Synthetic Biomolecules.
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- Pharmaceuticals (14248247), 2025, v. 18, n. 2, p. 175, doi. 10.3390/ph18020175
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Dual-Labeled Small Peptides in Cancer Imaging and Fluorescence-Guided Surgery: Progress and Future Perspectives.
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- Pharmaceuticals (14248247), 2025, v. 18, n. 2, p. 143, doi. 10.3390/ph18020143
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Assessing the applicability of tunicate skin-extracted cellulose as a base material for ultrasound gel.
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- Biotechnology & Bioprocess Engineering, 2025, v. 30, n. 1, p. 1, doi. 10.1007/s12257-024-00146-x
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- Article
Notch1 siRNA and AMD3100 Ameliorate Metabolic Dysfunction-Associated Steatotic Liver Disease.
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- Biomedicines, 2025, v. 13, n. 2, p. 486, doi. 10.3390/biomedicines13020486
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Advances and Challenges in the Pursuit of Disease-Modifying Osteoarthritis Drugs: A Review of 2010–2024 Clinical Trials.
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- Biomedicines, 2025, v. 13, n. 2, p. 355, doi. 10.3390/biomedicines13020355
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Development and Characterization of a Gelatin-Based Photoactive Hydrogel for Biomedical Application.
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- Journal of Functional Biomaterials, 2025, v. 16, n. 2, p. 43, doi. 10.3390/jfb16020043
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Transport Characteristics of Small Molecules Diffusing near Deforming Blood Cells.
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- Computation, 2025, v. 13, n. 2, p. 47, doi. 10.3390/computation13020047
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Analysis of the composition, characteristics, and antifungal properties of cutin in goji berry fruits at different developmental stages.
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- Frontiers in Plant Science, 2025, p. 1, doi. 10.3389/fpls.2025.1528881
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Small molecule metabolites drive plant rhizosphere microbial community assembly patterns.
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- Frontiers in Microbiology, 2025, p. 1, doi. 10.3389/fmicb.2025.1503537
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The Effect of GO Flake Size on Field-Effect Transistor (FET)-Based Biosensor Performance for Detection of Ions and PACAP 38.
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- Biosensors (2079-6374), 2025, v. 15, n. 2, p. 86, doi. 10.3390/bios15020086
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zDHHC-Mediated S-Palmitoylation in Skin Health and Its Targeting as a Treatment Perspective.
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- International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1673, doi. 10.3390/ijms26041673
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The Etiology of IgE-Mediated Food Allergy: Potential Therapeutics and Challenges.
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- International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1563, doi. 10.3390/ijms26041563
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Identification of CKAP2 as a Potential Target for Prevention of Gastric Cancer Progression: A Multi-Omics Study.
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- International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1557, doi. 10.3390/ijms26041557
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Niemann-Pick C-like Endolysosomal Dysfunction in DHDDS Patient Cells, a Congenital Disorder of Glycosylation, Can Be Treated with Miglustat.
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- International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1471, doi. 10.3390/ijms26041471
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Selective Up-Regulation of Tumor Suppressor Gene Retinoblastoma by Bisacridine Derivative Through Gene Promoter Quadruplex Structures for Cancer Treatment.
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- International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1417, doi. 10.3390/ijms26041417
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Preparation and bioevaluation of a <sup>99m</sup>Tc-labeled small-molecular radiotracer for PD-L1 imaging.
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- Journal of Radioanalytical & Nuclear Chemistry, 2025, v. 334, n. 2, p. 1621, doi. 10.1007/s10967-024-09901-z
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Asphaltenes biodegradation from heavy crude oils by the yeast Yarrowia lipolytica.
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- Bioprocess & Biosystems Engineering, 2025, v. 48, n. 3, p. 381, doi. 10.1007/s00449-024-03114-0
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Small Molecules Identified by an In Silico Docking Screen Targeting Anaphase-Promoting Complex/Cyclosome Subunit 1 (APC1) Potentiate Paclitaxel-Induced Breast Cancer Cell Death.
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- Molecules, 2025, v. 30, n. 4, p. 895, doi. 10.3390/molecules30040895
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Metabolomics Profiling and Advanced Methodologies for Wheat Stress Research.
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- Metabolites (2218-1989), 2025, v. 15, n. 2, p. 123, doi. 10.3390/metabo15020123
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Metabolomic Characterisation of Low-Density Lipoproteins Isolated from Iodixanol and KBr-Based Density Gradient Ultracentrifugation.
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- Metabolites (2218-1989), 2025, v. 15, n. 2, p. 68, doi. 10.3390/metabo15020068
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DrugDiff: small molecule diffusion model with flexible guidance towards molecular properties.
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- Journal of Cheminformatics, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13321-025-00965-x
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Preferential allosteric modulation of Otop1 channels by small molecule compounds.
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- Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07775-9
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Transcriptome analysis of liver and ileum reveals potential regulation of long non-coding RNA in pigs with divergent feed efficiency.
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- Animal Bioscience, 2025, v. 38, n. 4, p. 588, doi. 10.5713/ab.24.0434
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Treating paediatric Crohn's disease is challenging but new treatments hold promise.
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- Drugs & Therapy Perspectives, 2024, v. 40, n. 3, p. 121, doi. 10.1007/s40267-024-01056-x
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Extracellular proteolysis of tandemly duplicated pheromone propeptides affords additional complexity to bacterial quorum sensing.
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- PLoS Biology, 2024, v. 22, n. 8, p. 1, doi. 10.1371/journal.pbio.3002744
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A high-throughput behavioral screening platform for measuring chemotaxis by C. elegans.
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- PLoS Biology, 2024, v. 22, n. 6, p. 1, doi. 10.1371/journal.pbio.3002672
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Synthesis and Characterization of Highly Thiolated Silk Fibroin.
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- Macromolecular Chemistry & Physics, 2024, v. 225, n. 4, p. 1, doi. 10.1002/macp.202300340
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Mechanical Reinforcement of Thermoplastic Polyurethane Nanocomposites by Surface‐Modified Nanocellulose.
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- Macromolecular Chemistry & Physics, 2023, v. 224, n. 4, p. 1, doi. 10.1002/macp.202200383
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Layer‐by‐Layer Processed Efficient All‐Polymer Solar Cells Based on a Nonfused Polymerized Small Molecule Acceptor.
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- Macromolecular Chemistry & Physics, 2023, v. 224, n. 3, p. 1, doi. 10.1002/macp.202200395
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Synthesis of Novel (bis‐)1,5‐Disubstituted‐1H‐tetrazole‐Decorated Monomers and Their Respective Polymers via Thiol‐ene Polymerization.
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- Macromolecular Chemistry & Physics, 2023, v. 224, n. 3, p. 1, doi. 10.1002/macp.202200371
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