Works about RAPAMYCIN

Results: 5000

Letter to the Editor Re: Sirolimus to treat chronic and steroid‐resistant allograft rejection‐related fibrosis in pediatric liver transplantation.

Published in:

2025

By:

Cerminara, Dana;
Mysore, Krupa R.

Publication type:

Letter to the Editor

Response to the Letter to the Editor: Sirolimus for treating chronic and steroid‐resistant allograft rejection‐related fibrosis in pediatric liver transplantation.

Published in:

2025

By:

Quintero ‐ Bernabeu, Jesús;
Goñi, Javier J.;
Mercadal ‐ Hally, Maria;
Larrate ‐ King, Mauricio

Publication type:

Letter to the Editor

mTOR Modulates NLRP3 Inflammasome Activation via Nuclear Translocation and STAT1 Inhibition.

Published in:

European Journal of Immunology, 2025, v. 55, n. 6, p. 1, doi. 10.1002/eji.202451176

By:

González‐Dominguez, Alvaro;
Zhang, Shuling;
Boy‐Ruiz, Daniel;
Connors, Daniel;
de la Varga‐Martínez, Raquel;
Mock, Beverly A.;
Cordero, Mario D.

Publication type:

Article

New Insights into Unusual Genetic Disorder Pave the Way for Promising Treatments.

Published in:

PLoS Biology, 2013, v. 11, n. 8, p. 1, doi. 10.1371/journal.pbio.1001628

By:

Weaver, Janelle

Publication type:

Article

Induction of Biogenic Magnetization and Redox Control by a Component of the Target of Rapamycin Complex 1 Signaling Pathway.

Published in:

PLoS Biology, 2012, v. 10, n. 2, p. 1, doi. 10.1371/journal.pbio.1001269

By:

Nishida, Keiji;
Silver, Pamela A.

Publication type:

Article

Dysregulation of the Norepinephrine Transporter Sustains Cortical Hypodopaminergia and Schizophrenia- Like Behaviors in Neuronal Rictor Null Mice.

Published in:

PLoS Biology, 2010, v. 8, n. 6, p. 1, doi. 10.1371/journal.pbio.1000393

By:

Siuta, Michael A.;
Robertson, Sabrina D.;
Kocalis, Heidi;
Saunders, Christine;
Gresch, Paul J.;
Khatri, Vivek;
Shiota, Chiyo;
Kennedy, J. Philip;
Lindsley, Craig W.;
Daws, Lynette C.;
Polley, Daniel B.;
Veenstra-Vanderweele, Jeremy;
Stanwood, Gregg D.;
Magnuson, Mark A.;
Niswender, Kevin D.;
Galli, Aurelio

Publication type:

Article

Rictor/TORC2 Regulates Caenorhabditis elegans Fat Storage, Body Size, and Development through sgk-1.

Published in:

PLoS Biology, 2009, v. 7, n. 3, p. e1000060, doi. 10.1371/journal.pbio.1000060

By:

Jones, Kevin T.;
Greer, Elisabeth R.;
Pearce, David;
Ashrafi, Kaveh

Publication type:

Article

Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2.

Published in:

PLoS Biology, 2009, v. 7, n. 2, p. e1000038, doi. 10.1371/journal.pbio.1000038

By:

Feldman, Morris E.;
Apsel, Beth;
Uotila, Aino;
Loewith, Robbie;
Knight, Zachary A.;
Ruggero, Davide;
Shokat, Kevan M.

Publication type:

Article

Lack of efficacy of m TOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2<sup> −/−</sup> mice.

Published in:

Liver International, 2015, v. 35, n. 4, p. 1451, doi. 10.1111/liv.12494

By:

Bridle, Kim R.;
Sobbe, Amy L.;
Guzman, C. Erika;
Santrampurwala, Nishreen;
Jaskowski, Lesley A.;
Clouston, Andrew D.;
Campbell, Catherine M.;
Nathan Subramaniam, V.;
Crawford, Darrell HG

Publication type:

Article

Additive effect of sirolimus and anti-death receptor 5 agonistic antibody against hepatocellular carcinoma.

Published in:

Liver International, 2013, v. 33, n. 9, p. 1441, doi. 10.1111/liv.12275

By:

Kawahara, Toshiyasu;
Toso, Christian;
Yamaguchi, Keisuke;
Cader, Sonia;
Douglas, Donna N.;
Nourbakhsh, Mahra;
Lewis, Jamie T.;
Churchill, Thomas A.;
Yagita, Hideo;
Kneteman, Norman M.

Publication type:

Article

The role of mTOR inhibitors in the treatment of hepatocellular carcinoma.

Published in:

Liver International, 2013, v. 33, n. 8, p. 1133, doi. 10.1111/liv.12213

By:

Huang, Yi‐Hsiang;
Lin, Han‐Chieh

Publication type:

Article

Rapamycin and CCI-779 inhibit the mammalian target of rapamycin signalling in hepatocellular carcinoma.

Published in:

Liver International, 2010, v. 30, n. 1, p. 65, doi. 10.1111/j.1478-3231.2009.02117.x

By:

Hui, Ivan Chun-Fai;
Tung, Edmund Kwok-Kwan;
Sze, Karen Man-Fong;
Yick-Pang Ching;
Ng, Irene Oi-Lin

Publication type:

Article

Phosphorylation of p70S6 kinase predicts overall survival in patients with clear margin-resected hepatocellular carcinoma.

Published in:

Liver International, 2009, v. 29, n. 3, p. 399, doi. 10.1111/j.1478-3231.2008.01798.x

By:

Baba, Hideo A.;
Wohlschlaeger, Jeremias;
Cicinnati, Vito R.;
Hilgard, Philip;
Lang, Hauke;
Sotiropoulos, Georgios C.;
Takeda, Atsushi;
Beckebaum, Susanne;
Schmitz, Klaus J.

Publication type:

Article

Effects of microRNA‐1271 on ovarian cancer via inhibition of epithelial‐mesenchymal transition and cisplatin resistance.

Published in:

Journal of Obstetrics & Gynaecology Research, 2019, v. 45, n. 11, p. 2243, doi. 10.1111/jog.14079

By:

Chen, Yanyan;
Wang, Li;
Zhou, Jiefang

Publication type:

Article

Moderate mammalian target of rapamycin inhibition induces autophagy in HTR8/SVneo cells via O-linked β-N-acetylglucosamine signaling.

Published in:

Journal of Obstetrics & Gynaecology Research, 2017, v. 43, n. 10, p. 1585, doi. 10.1111/jog.13410

By:

Zhang, Qiuxia;
Na, Quan;
Song, Weiwei

Publication type:

Article

Rapamycin found to prolong ketamine's antidepressant effects.

Published in:: Brown University Psychopharmacology Update, 2020, v. 31, n. 6, p. 7, doi. 10.1002/pu.30586
Publication type:: Article

The effect of mTOR inhibition on obstructive hydrocephalus in patients with tuberous sclerosis complex (TSC) related subependymal giant cell astrocytoma (SEGA).

Published in:

Journal of Neuro-Oncology, 2020, v. 147, n. 3, p. 731, doi. 10.1007/s11060-020-03487-8

By:

Weidman, Danielle R.;
Palasamudram, Sunitha;
Zak, Maria;
Whitney, Robyn;
McCoy, Blathnaid;
Bouffet, Eric;
Taylor, Michael;
Shroff, Manohar;
Bartels, Ute

Publication type:

Article

Rapamycin and hydroxychloroquine combination alters macrophage polarization and sensitizes glioblastoma to immune checkpoint inhibitors.

Published in:

Journal of Neuro-Oncology, 2020, v. 146, n. 3, p. 417, doi. 10.1007/s11060-019-03360-3

By:

Hsu, Sanford P. C.;
Chen, Yi-Ching;
Chiang, Hsin-Chien;
Huang, Yi-Chun;
Huang, Cheng-Chung;
Wang, Hsin-Ell;
Wang, Yu-Shang;
Chi, Kwan-Hwa

Publication type:

Article

Phase II study of mTORC1 inhibition by everolimus in neurofibromatosis type 2 patients with growing vestibular schwannomas.

Published in:

Journal of Neuro-Oncology, 2015, v. 122, n. 2, p. 313, doi. 10.1007/s11060-014-1710-0

By:

Goutagny, Stéphane;
Raymond, Eric;
Esposito-Farese, Marina;
Trunet, Stéphanie;
Mawrin, Christian;
Bernardeschi, Daniele;
Larroque, Béatrice;
Sterkers, Olivier;
Giovannini, Marco;
Kalamarides, Michel

Publication type:

Article

Vandetanib plus sirolimus in adults with recurrent glioblastoma: results of a phase I and dose expansion cohort study.

Published in:

Journal of Neuro-Oncology, 2015, v. 121, n. 3, p. 627, doi. 10.1007/s11060-014-1680-2

By:

Chheda, Milan;
Wen, Patrick;
Hochberg, Fred;
Chi, Andrew;
Drappatz, Jan;
Eichler, April;
Yang, Daniel;
Beroukhim, Rameen;
Norden, Andrew;
Gerstner, Elizabeth;
Betensky, Rebecca;
Batchelor, Tracy

Publication type:

Article

EGF signalling and rapamycin-mediated mTOR inhibition in glioblastoma multiforme evaluated by phospho-specific flow cytometry.

Published in:

Journal of Neuro-Oncology, 2013, v. 112, n. 1, p. 49, doi. 10.1007/s11060-012-1035-9

By:

Cornez, Isabelle;
Joel, Mrinal;
Taskén, Kjetil;
Langmoen, Iver;
Glover, Joel;
Berge, Torunn

Publication type:

Article

Overexpression of Golgi phosphoprotein-3 (GOLPH3) in glioblastoma multiforme is associated with worse prognosis.

Published in:

Journal of Neuro-Oncology, 2012, v. 110, n. 2, p. 195, doi. 10.1007/s11060-012-0970-9

By:

Zhou, Jinxu;
Xu, Tao;
Qin, Rong;
Yan, Yong;
Chen, Chao;
Chen, Yuanyuan;
Yu, Hongyu;
Xia, Chunyan;
Lu, Yicheng;
Ding, Xuehua;
Wang, Yuhai;
Cai, Xuejian;
Chen, Juxiang

Publication type:

Article

Systemic rapamycin alone may not be a treatment option for malignant glioma: evidence from an in vivo study.

Published in:

Journal of Neuro-Oncology, 2012, v. 108, n. 1, p. 53, doi. 10.1007/s11060-012-0804-9

By:

Mendiburu-Eliçabe, Marina;
Yin, Dali;
Hadaczek, Piotr;
Zhai, Yuying;
Forsayeth, John;
Bankiewicz, Krystof

Publication type:

Article

Association between AKT/mTOR signalling pathway and malignancy grade of human gliomas.

Published in:

Journal of Neuro-Oncology, 2011, v. 103, n. 3, p. 453, doi. 10.1007/s11060-010-0424-1

By:

Li, Xue-yuan;
Zhang, Lian-qun;
Zhang, Xue-guang;
Li, Xin;
Ren, Yu-bo;
Ma, Xiang-yu;
Li, Xin-gang;
Wang, Le-xin

Publication type:

Article

mTORC1 activation in childhood ependymoma and response to sirolimus.

Published in:

2011

By:

Bowers, Daniel;
Kucejova, Blanka;
Margraf, Linda;
Gargan, Lynn;
Brugarolas, James

Publication type:

Report

Phase 2 trial of erlotinib plus sirolimus in adults with recurrent glioblastoma.

Published in:

Journal of Neuro-Oncology, 2010, v. 96, n. 2, p. 219, doi. 10.1007/s11060-009-9950-0

By:

Reardon, David;
Desjardins, Annick;
Vredenburgh, James;
Gururangan, Sridharan;
Friedman, Allan;
Herndon, James;
Marcello, Jennifer;
Norfleet, Julie;
McLendon, Roger;
Sampson, John;
Friedman, Henry

Publication type:

Article

A pilot study of everolimus and gefitinib in the treatment of recurrent glioblastoma (GBM).

Published in:

Journal of Neuro-Oncology, 2009, v. 92, n. 1, p. 99, doi. 10.1007/s11060-008-9741-z

By:

Teri Kreisl;
Andrew Lassman;
Paul Mischel;
Neal Rosen;
Howard Scher;
Julie Teruya-Feldstein;
David Shaffer;
Eric Lis;
Lauren Abrey

Publication type:

Article

Specific mTOR inhibitor rapamycin enhances cytotoxicity induced by alkylating agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea (ACNU) in human U251 malignant glioma cells.

Published in:

Journal of Neuro-Oncology, 2007, v. 84, n. 3, p. 233, doi. 10.1007/s11060-007-9371-x

By:

Kazuhiro Tanaka;
Takashi Sasayama;
Katsu Mizukawa;
Atsufumi Kawamura;
Takeshi Kondoh;
Kohkichi Hosoda;
Toshiyoshi Fujiwara;
Eiji Kohmura

Publication type:

Article

Rapamycin rescues mitochondrial dysfunction in cells carrying the m.8344A > G mutation in the mitochondrial tRNA<sup>Lys</sup>.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00519-z

By:

Capristo, Mariantonietta;
Del Dotto, Valentina;
Tropeano, Concetta Valentina;
Fiorini, Claudio;
Caporali, Leonardo;
La Morgia, Chiara;
Valentino, Maria Lucia;
Montopoli, Monica;
Carelli, Valerio;
Maresca, Alessandra

Publication type:

Article

Streamlined Embedding of Cell Monolayers on Gridded Glass-Bottom Imaging Dishes for Correlative Light and Electron Microscopy.

Published in:

Microscopy & Microanalysis, 2010, v. 16, n. 6, p. 747, doi. 10.1017/S1431927610094092

By:

Hanson, Hugo H.;
Reilly, James E.;
Lee, Rebecca;
Janssen, William G.;
Phillips, Greg R.

Publication type:

Article

Curcumin affects autophagy of prolactinoma cells by upregulating miR‐206 to exert antitumor effects.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 6, p. 1, doi. 10.1002/jbt.23734

By:

Duan, Jia‐feng;
Zhang, Qiu‐juan;
Zhu, Jin;
Lu, Jia‐hui

Publication type:

Article

Activation of autophagy promotes the inhibitory effect of curcumin analog EF‐24 against MDA‐MB‐231 cancer cells.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 2, p. 1, doi. 10.1002/jbt.23642

By:

Zhao, Yin‐Yin;
Li, Jun;
Wang, Hao‐Qi;
Zheng, Hao‐Bo;
Ma, Shi‐Wei;
Zhou, Guang‐Zhou

Publication type:

Article

Silencing of GDF11 suppresses hepatocyte apoptosis to relieve LPS/D‐GalN acute liver failure.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 1, p. 1, doi. 10.1002/jbt.23577

By:

Zhou, Rongsheng;
Li, Shuang;
Wang, Qun;
Bi, Yang;
Li, Xiaogang;
Wang, Qiang

Publication type:

Article

The ameliorative effects of cannabidiol on methotrexate‐induced neuroinflammation and neuronal apoptosis via inhibiting endoplasmic reticulum and mitochondrial stress.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 1, p. 1, doi. 10.1002/jbt.23571

By:

Unlu, Melike D.;
Asci, Halil;
Yusuf Tepebasi, M.;
Arlioglu, Melih;
Huseynov, Ibrahim;
Ozmen, Ozlem;
Sezer, Serdar;
Demirci, Serpil

Publication type:

Article

Sulfamethizole attenuates poloxamer 407‐induced atherosclerotic neointima formation via inhibition of mTOR in C57BL/6 mice.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 5, p. 1, doi. 10.1002/jbt.23322

By:

Solanki, Ankita;
Savla, Shreya R.;
Borkar, Maheshkumar R.;
Bhatt, Lokesh K.

Publication type:

Article

Low‐dose rapamycin prevents Ang‐II‐induced toxicity in Leydig cells and testicular dysfunction in hypertensive SHR model.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 9, p. 1, doi. 10.1002/jbt.23128

By:

Kuo, Wei‐Wen;
Baskaran, Rathinasamy;
Lin, Jing‐Ying;
Day, Cecilia Hsuan;
Lin, Yueh‐Min;
Ho, Tsung‐Jung;
Chen, Ray‐Jade;
Lin, Mei‐Yi;
Padma, Viswanadha Vijaya;
Huang, Chih‐Yang

Publication type:

Article

Modulation of translation-initiation in CHO-K1 cells by rapamycin-induced heterodimerization of engineered eIF4G fusion proteins.

Published in:

Biotechnology & Bioengineering, 2003, v. 83, n. 2, p. 210, doi. 10.1002/bit.10662

By:

Stefan Schlatter;
Claudia Senn;
Martin Fussenegger

Publication type:

Article

mTOR and PTEN expression in non-small cell lung cancer: analysis by real-time fluorescence quantitative polymerase chain reaction and immunohistochemistry.

Published in:

Surgery Today, 2012, v. 42, n. 5, p. 419, doi. 10.1007/s00595-011-0028-1

By:

Wang, Liang;
Yue, Wentao;
Zhang, Lina;
Zhao, Xiaoting;
Wang, Yue;
Xu, Shaofa

Publication type:

Article

Complex vascular anomalies.

Published in:

Pediatric Surgery International, 2013, v. 29, n. 10, p. 1023, doi. 10.1007/s00383-013-3393-6

By:

Azizkhan, Richard

Publication type:

Article

Immunomodulatory role of branched-chain amino acids.

Published in:

Nutrition Reviews, 2018, v. 76, n. 11, p. 840, doi. 10.1093/nutrit/nuy037

By:

Bonvini, Andrea;
Coqueiro, Audrey Y;
Tirapegui, Julio;
Calder, Philip C;
Rogero, Marcelo M

Publication type:

Article

Leucine and Protein Synthesis: mTOR and Beyond.

Published in:

Nutrition Reviews, 2007, v. 65, n. 3, p. 122, doi. 10.1301/nr.2007.mar.122-129

By:

Stipanuk, Martha H.

Publication type:

Article

Determinants of intra-specific variation in basal metabolic rate.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2013, v. 183, n. 1, p. 27, doi. 10.1007/s00360-012-0698-z

By:

Konarzewski, Marek;
Książek, Aneta

Publication type:

Article

Effects of sirolimus in lymphangioleiomyomatosis patients on lung cysts and pulmonary function: long-term follow-up observational study.

Published in:

2020

By:

Kim, Cherry;
Do, Kyung-Hyun;
Cha, Jaehyung;
Song, Jin Woo;
Lee, Sang Min;
Lee, Ki Yeol

Publication type:

journal article

mTOR-inhibitor treatment of metastatic renal cell carcinoma: contribution of Choi and modified Choi criteria assessed in 2D or 3D to evaluate tumor response.

Published in:

2016

By:

Lamuraglia, M.;
Raslan, S.;
Elaidi, R.;
Oudard, S.;
Escudier, B.;
Slimane, K.;
Penna, R.;
Wagner, M.;
Lucidarme, O.;
Penna, R Renard

Publication type:

journal article

Impact of sirolimus-eluting stent fractures without early cardiac events on long-term clinical outcomes: A multislice computed tomography study.

Published in:

European Radiology, 2014, v. 24, n. 5, p. 1006, doi. 10.1007/s00330-014-3118-9

By:

Ito, Tsuyoshi;
Kimura, Masashi;
Ehara, Mariko;
Terashima, Mitsuyasu;
Nasu, Kenya;
Kinoshita, Yoshihisa;
Habara, Maoto;
Tsuchikane, Etsuo;
Suzuki, Takahiko

Publication type:

Article

HMGB proteins involved in TOR signaling as general regulators of cell growth by controlling ribosome biogenesis.

Published in:

Current Genetics, 2018, v. 64, n. 6, p. 1205, doi. 10.1007/s00294-018-0842-8

By:

Vizoso-Vázquez, A.;
Barreiro-Alonso, A.;
González-Siso, M. I.;
Rodríguez-Belmonte, E.;
Lamas-Maceiras, M.;
Cerdán, M. E.

Publication type:

Article

Protection mechanisms against aberrant metabolism of sphingolipids in budding yeast.

Published in:

Current Genetics, 2018, v. 64, n. 5, p. 1021, doi. 10.1007/s00294-018-0826-8

By:

Tani, Motohiro;
Funato, Kouichi

Publication type:

Article

Control of RNA polymerase II-transcribed genes by direct binding of TOR kinase.

Published in:

Current Genetics, 2018, v. 64, n. 1, p. 131, doi. 10.1007/s00294-017-0738-z

By:

Grove, Anne

Publication type:

Article

Target of rapamycin signaling mediates vacuolar fragmentation.

Published in:

Current Genetics, 2017, v. 63, n. 1, p. 35, doi. 10.1007/s00294-016-0616-0

By:

Stauffer, Bobbiejane;
Powers, Ted

Publication type:

Article

Regulation of TORC1 by ubiquitin through non-covalent binding.

Published in:

Current Genetics, 2016, v. 62, n. 3, p. 553, doi. 10.1007/s00294-016-0581-7

By:

Jiang, Yu

Publication type:

Article