Works about PYROPTOSIS

Results: 2046

Inhibition of hsa_circ_0003314 contributes to trophoblast cell migration and invasion and inhibits pyroptosis in preeclampsia.

Published in:

Histochemistry & Cell Biology, 2025, v. 163, n. 1, p. 1, doi. 10.1007/s00418-025-02384-3

By:

Zhou, Yun;
Chen, Yuqing;
Li, Lihua;
Lin, Lizhen

Publication type:

Article

Targeting cholesterol-driven pyroptosis: a promising strategy for the prevention and treatment of atherosclerosis.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10554-8

By:

Tang, Yuehong;
Tong, Wenjuan;
Peng, Yujiao;
Sun, Shaowei

Publication type:

Article

LncRNA OIP5‐AS1/miR‐186‐5p/NLRP3 Axis Contributes to Sepsis‐Induced Kidney Injury Through Enhancing NLRP3 Inflammasome Activation.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 5, p. 1, doi. 10.1002/jbt.70305

By:

Li, Jingdong;
Dong, Zhe;
Tang, Liting;
Liu, Lu;
Su, Cuijing;
Yu, Shan

Publication type:

Article

Mechanistic role of pyroptosis in Kawasaki disease: An integrative bioinformatics analysis of immune dysregulation, machine learning-based biomarker discovery, WGCNA, and drug repurposing insights.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0323597

By:

Wang, Chen;
Wu, Qinchao;
Chen, Jie;
Wang, Jun;
Li, Dan

Publication type:

Article

Necrosis-like cell death modes in heart failure: the influence of aetiology and the effects of RIP3 inhibition.

Published in:

Basic Research in Cardiology, 2025, v. 120, n. 2, p. 373, doi. 10.1007/s00395-025-01101-4

By:

Jarabicová, Izabela;
Horváth, Csaba;
Hrdlička, Jaroslav;
Boroš, Almos;
Olejníčková, Veronika;
Zábrodská, Eva;
Hubáčková, Soňa Štemberková;
Šutovská, Hana Mauer;
Molčan, Ľuboš;
Kopkan, Libor;
Chudý, Martin;
Kura, Branislav;
Kaločayová, Barbora;
Goncalvesová, Eva;
Neckář, Jan;
Zeman, Michal;
Kolář, František;
Adameová, Adriana

Publication type:

Article

The Rough Morphotype of Mycobacterium abscessus Enhances Its Virulence Through ROS/p65/NLRP3/GSDMD‐Mediated Macrophage Pyroptosis.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2025, v. 52, n. 6, p. 1, doi. 10.1111/1440-1681.70034

By:

Li, Jingren;
Li, Juan;
Li, Anqi;
Tan, Zhili;
Fan, Junsheng;
He, Siyuan;
Guo, Qi;
Xu, Liyun;
Chu, Haiqing

Publication type:

Article

Pyroptosis in Pulpitis.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 5867, doi. 10.2147/JIR.S516502

By:

Wei, Xiaorui;
Ran, Shidian;
Yan, Xingrui;
Huang, Jindie;
Xue, Linyu;
He, Tong-Chuan;
Zhang, Hongmei;
Wu, Si

Publication type:

Article

Gubi Decoction Ameliorates Porous Cartilage Endplate in an Intervertebral Disc Degeneration Model Mouse Through Inhibition of NF-κB Activity and Pyroptosis.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 5293, doi. 10.2147/JIR.S492365

By:

Yao, Sai;
Li, Yanan;
Ruan, Hongfeng;
Wu, Lianguo;
Zeng, Hanbing

Publication type:

Article

Annexin A: Cell Death, Inflammation, and Translational Medicine.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 5655, doi. 10.2147/JIR.S511439

By:

Qian, Zibing;
Li, Ziyi;
Peng, Xuebin;
Mao, Yongwu;
Mao, Xiaorong;
Li, Junfeng

Publication type:

Article

Tumor-Intrinsic SIRPA Drives Pyroptosis Evasion in Head and Neck Cancer.

Published in:

Journal of Dental Research, 2025, v. 104, n. 6, p. 645, doi. 10.1177/00220345241305590

By:

Song, A.;
Yang, Q.-C.;
Wang, W.-D.;
Wang, S.;
Li, H.;
Wu, L.;
Sun, Z.-J.

Publication type:

Article

LncRNA29RIK in macrophages promotes LPS- mediated sensitivity to obesity.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1574507

By:

Wang, Rong;
Gao, Yunhuan;
Wang, Ya;
Zhang, Yuan;
Yang, Rongcun

Publication type:

Article

Inhibition of histone deacetylase 6 activity mitigates neurological impairment and post-hemorrhagic hydrocephalus after intraventricular hemorrhage by modulating pyroptosis and autophagy pathways.

Published in:

Fluids & Barriers of the CNS, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12987-025-00658-5

By:

Wang, Hao-Xiang;
Deng, Zi-Ang;
Li, Yuan-You;
Li, Jun;
Chen, Ya-Xing;
Zhao, Yan-Jie;
Huang, Ke-Ru;
Tian, Wei-Ning;
Tong, Ai-Ping;
Zhou, Liang-Xue

Publication type:

Article

Predicting prognosis, immune landscape, and drug targets with a novel signature for hepatocellular carcinoma.

Published in:

Technology & Health Care, 2025, v. 33, n. 3, p. 1367, doi. 10.1177/09287329241296358

By:

Qiu, Xinqi;
Huang, Wentao;
Liang, Jun;
Chen, Hao;
Sha, Weihong;
Lyu, Yanlin;
Chen, Kequan;
Yang, Hongwei;
Zhang, Qingfang

Publication type:

Article

EZH2-H3K27me3-Mediated Epigenetic Silencing of DKK1 Induces Nucleus Pulposus Cell Pyroptosis in Intervertebral Disc Degeneration by Activating NLRP3 and NAIP/NLRC4.

Published in:

Inflammation, 2025, v. 48, n. 2, p. 902, doi. 10.1007/s10753-024-02096-1

By:

Yao, Qijun;
Lei, Yue;
Zhang, Yongxu;
Chen, Haoran;
Dong, Xiaowei;
Ye, Zhiqiang;
Liang, Haidong

Publication type:

Article

Targeting pyroptosis for cancer immunotherapy: mechanistic insights and clinical perspectives.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02344-4

By:

Huang, Chen;
Li, Jiayi;
Wu, Ruiyan;
Li, Yangqian;
Zhang, Chenliang

Publication type:

Article

Circ-PSMB1 knockdown inhibits the pyroptosis of ox-LDL treated human aortic cells via the miR-624-3p/ASC axis.

Published in:

Journal of Cardiothoracic Surgery, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13019-025-03457-z

By:

Zhou, Yupu;
Guo, Yongchuan

Publication type:

Article

Lanthanide-specific doping in vacancy-engineered piezocatalysts induces lysosomal destruction and tumor cell pyroptosis.

Published in:

Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03411-0

By:

Li, Xiaoyan;
Wang, Ying;
Cao, Xinyue;
Song, Xinran;
Chen, Liang;
Chang, Meiqi;
Chen, Yu;
Huang, Bingcang

Publication type:

Article

Remimazolam Combined with Andrographolide Improve Postoperative Cognitive Dysfunction in Rats after Cardiopulmonary Bypass through the AMPK/SIRT1 Signaling Pathway.

Published in:

Journal of Integrative Neuroscience, 2025, v. 24, n. 1, p. 1, doi. 10.31083/JIN25665

By:

Chong Chen;
Lixia Lan;
Kai Xu

Publication type:

Article

Copper Overload Promotes β-amyloid Induced NLRP3/Caspase-1/GSDMD-Mediated Pyroptosis in Alzheimer's Disease.

Published in:

Journal of Integrative Neuroscience, 2024, v. 23, n. 10, p. 1, doi. 10.31083/j.jin2310194

By:

Min-Juan Zhu;
Ling Zhang;
Chang-Peng Wang

Publication type:

Article

The Role of Pyroptosis in Alzheimer's Disease.

Published in:

Journal of Integrative Neuroscience, 2023, v. 22, n. 5, p. 1, doi. 10.31083/j.jin2205129

By:

Yanxiu Ju;
Ling Zhao;
Songtao Li;
Qing Zhao

Publication type:

Article

Gastrodin suppresses pyroptosis and exerts neuroprotective effect in traumatic brain injury model by inhibiting NLRP3 inflammasome signaling pathway.

Published in:

Journal of Integrative Neuroscience, 2022, v. 21, n. 2, p. 1, doi. 10.31083/j.jin2102072

By:

Fei Yang;
Guangzhao Li;
Bin Lin;
Kaipeng Zhang

Publication type:

Article

GLP-1RAs inhibit the activation of the NLRP3 inflammasome signaling pathway to regulate mouse renal podocyte pyroptosis.

Published in:

Acta Diabetologica, 2024, v. 61, n. 2, p. 225, doi. 10.1007/s00592-023-02184-y

By:

Li, Xiang;
Jiang, Xiao;
Jiang, Mei;
Wang, Zhi-feng;
Zhao, Tao;
Cao, Si-ming;
Li, Qiu-Mei

Publication type:

Article

Zhenbao Pill Attenuates Microglia Activation to Improve Spinal Cord Injury via miR-214-5p/SOX4/β-catenin Axis.

Published in:

Journal of Physiological Investigation (JPI), 2024, v. 67, n. 5, p. 281, doi. 10.4103/ejpi.EJPI-D-23-00025

By:

Huan, Yanqiang;
He, Juan;
Li, Pengfei;
Wang, Fei;
Zhou, Huidong;
He, Yongxiong

Publication type:

Article

Cigarette Smoke Extract and Lipopolysaccharide Induce Pyroptosis in Pulmonary Microvascular Endothelial Cells of Rats.

Published in:

Bulletin of Experimental Biology & Medicine, 2023, v. 174, n. 6, p. 728, doi. 10.1007/s10517-023-05780-8

By:

Wang, Q.;
Liu, M.;
Liu, Y.;
Zhang, Z.;
Bai, Z.

Publication type:

Article

Activation of Ca<sup>2+</sup>/Calmodulin-Dependent Protein Kinase II (CaMKII) with Lidocaine Provokes Pyroptosis of Glioblastoma Cells.

Published in:

Bulletin of Experimental Biology & Medicine, 2021, v. 171, n. 3, p. 297, doi. 10.1007/s10517-021-05216-1

By:

Zhou, B.;
Lin, Y.;
Chen, S.;
Cai, J.;
Luo, Z.;
Yu, S.;
Lu, J.

Publication type:

Article

Calm the Flame of Pyroptosis - a New Approach to Soothe Skin Redness and Irritation.

Published in:

SOFW Journal (English version), 2025, v. 151, n. 4, p. 40

By:

Bönzli, Eva

Publication type:

Article

Upregulated dual oxidase 1-induced oxidative stress and caspase-1-dependent pyroptosis reflect the etiologies of heart failure.

Published in:

BMC Molecular & Cell Biology, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12860-024-00506-8

By:

Li, Yan Song;
Xia, Jingwen;
Chen, Chang Yuan;
Ren, Shu Hong;
He, Mao Rong

Publication type:

Article

Knockdown of ELF4 aggravates renal injury in ischemia/reperfusion mice through promotion of pyroptosis, inflammation, oxidative stress, and endoplasmic reticulum stress.

Published in:

BMC Molecular & Cell Biology, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12860-023-00485-2

By:

Li, Li;
Wang, Shunying;
Wang, Wenming

Publication type:

Article

HMGB1 mediates lipopolysaccharide-induced macrophage autophagy and pyroptosis.

Published in:

BMC Molecular & Cell Biology, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12860-023-00464-7

By:

Shang, Jiawei;
Zhao, Feng;
Cao, Yongmei;
Ping, Feng;
Wang, Wei;
Li, Yingchuan

Publication type:

Article

Ceramide induces pyroptosis through TXNIP/NLRP3/GSDMD pathway in HUVECs.

Published in:

BMC Molecular & Cell Biology, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12860-022-00459-w

By:

Liu, Fangfang;
Zhang, Yangyang;
Shi, Yining;
Xiong, Kai;
Wang, Fugui;
Yang, Jin

Publication type:

Article

Exogenous 8-hydroxydeoxyguanosine attenuates doxorubicin-induced cardiotoxicity by decreasing pyroptosis in H9c2 cardiomyocytes.

Published in:

BMC Molecular & Cell Biology, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12860-022-00454-1

By:

Hwang, Soyoung;
Kim, Se-Hee;
Yoo, Kwai Han;
Chung, Myung-Hee;
Lee, Jin Woo;
Son, Kuk Hui

Publication type:

Article

HIF-1α facilitates glioma proliferation and invasion by activating pyroptosis signaling axis.

Published in:

Chinese Neurosurgical Journal, 2024, v. 10, n. 1, p. 1, doi. 10.1186/s41016-024-00366-3

By:

Wang, Xin-Wei;
Fu, Hao;
Zhang, Ya-Min

Publication type:

Article

The Role of Pyroptosis in Ischemic and Reperfusion Injury of the Heart.

Published in:

2021

By:

Popov, Sergey V.;
Maslov, Leonid N.;
Naryzhnaya, Natalia V.;
Mukhomezyanov, Alexandr V.;
Krylatov, Andrey V.;
Tsibulnikov, Sergey Y.;
Ryabov, Vyacheslav V.;
Cohen, Michael V.;
Downey, James M.

Publication type:

journal article

Anisodamine hydrobromide ameliorates acute lung injury via inhibiting pyroptosis in murine sepsis model.

Published in:

Immunopharmacology & Immunotoxicology, 2024, v. 46, n. 5, p. 662, doi. 10.1080/08923973.2024.2386331

By:

Zhang, Bihua;
Luo, Li;
Xiong, Shiqiang;
Xiao, Yuanyuan;
Zhang, Ting;
Xiang, Tao

Publication type:

Article

Isoquercetin alleviates sleep deprivation dependent hippocampal neurons damage by suppressing NLRP3-induced pyroptosis.

Published in:

Immunopharmacology & Immunotoxicology, 2022, v. 44, n. 5, p. 766, doi. 10.1080/08923973.2022.2082976

By:

Zhou, Hairui;
Wu, Jingru;
Gong, Yu;
Zhou, Zilong;
Wang, Jingtao

Publication type:

Article

Mechanism of miR-126 in hypoxia-reoxygenation-induced cardiomyocyte pyroptosis by regulating HMGB1 and NLRP3 inflammasome.

Published in:

Immunopharmacology & Immunotoxicology, 2022, v. 44, n. 4, p. 500, doi. 10.1080/08923973.2022.2054819

By:

Fei, Ling;
Zhang, Ning;
Zhang, Jun

Publication type:

Article

Quercetin attenuates lipopolysaccharide-mediated inflammatory injury in human nasal epithelial cells via regulating miR-21/DMBT1/NF-κB axis.

Published in:

Immunopharmacology & Immunotoxicology, 2022, v. 44, n. 1, p. 7, doi. 10.1080/08923973.2021.1988963

By:

Cheng, Ji;
Luo, Xian-qing;
Chen, Fa-sheng

Publication type:

Article

Combination of tetrandrine and 3-n-butylphthalide protects against cerebral ischemia-reperfusion injury via ATF2/TLR4 pathway.

Published in:

Immunopharmacology & Immunotoxicology, 2021, v. 43, n. 6, p. 749, doi. 10.1080/08923973.2021.1979036

By:

Li, Cunfang;
Chai, Aijun;
Gao, Yongchao;
Qi, Xuan;
Zheng, Xuguang

Publication type:

Article

Effects of stem cell-derived exosomes on neuronal apoptosis and inflammatory cytokines in rats with cerebral ischemia-reperfusion injury via PI3K/AKT pathway-mediated mitochondrial apoptosis.

Published in:

Immunopharmacology & Immunotoxicology, 2021, v. 43, n. 6, p. 731, doi. 10.1080/08923973.2021.1976794

By:

Zhang, Ying;
Yu, Jun;
Liu, Jing;
Liu, Hongbiao;
Li, Jing

Publication type:

Article

EZH2–STAT3 signaling pathway regulates GSDMD-mediated pyroptosis in glioblastoma.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02105-0

By:

Yu, Dong;
Wang, Shuai;
Wang, Jiajun;
Zhang, Kang;
Niu, Zihui;
Lin, Ning

Publication type:

Article

The downregulation of SCGN induced by lipotoxicity promotes NLRP3-mediated β-cell pyroptosis.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02107-y

By:

Ouyang, Shuhui;
Xiang, Sunmin;
Wang, Xin;
Yang, Xin;
Liu, Xuan;
Zhang, Meilin;
Zhou, Yiting;
Xiao, Yang;
Zhou, Lingzhi;
Fan, Gang;
Yang, Jing

Publication type:

Article

CCL11 released by GSDMD-mediated macrophage pyroptosis regulates angiogenesis after hindlimb ischemia.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-023-01764-9

By:

Wang, Yiwen;
Gao, Yang;
Shi, Huairui;
Gao, Rifeng;
Yang, Ji'e;
Qu, Ya'nan;
Hu, Shiyu;
Zhang, Jian;
Wang, Jingpu;
Cao, Jiatian;
Zhang, Feng;
Ge, Junbo

Publication type:

Article

HAX-1 interferes in assembly of NLRP3-ASC to block microglial pyroptosis in cerebral I/R injury.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02005-3

By:

Guo, Xin-bin;
Deng, Xin;
Wang, Jingjing;
Qi, Yuruo;
Zhao, Wen;
Guan, Sheng

Publication type:

Article

Tumors cells with mismatch repair deficiency induce hyperactivation of pyroptosis resistant to cell membrane damage but are more sensitive to co-treatment of IFN-γ and TNF-α to PANoptosis.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01984-7

By:

Li, Huiyan;
Ni, Hengli;
Li, Ying;
Zhou, Aijun;
Qin, Xiaokang;
Li, Yuqing;
Che, Liheng;
Mo, Hui;
Qin, Chao;
Li, Jianming

Publication type:

Article

Neutrophil extracellular traps promote invasion and metastasis via NLRP3-mediated oral squamous cell carcinoma pyroptosis inhibition.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01982-9

By:

Zhai, Rundong;
Gong, Zizhen;
Wang, Mengqi;
Ni, Zihui;
Zhang, Jiayi;
Wang, Mengyao;
Zhang, Yu;
Zeng, Fanrui;
Gu, Ziyue;
Chen, Xingyu;
Wang, Xiudi;
Zhou, Pengcheng;
Liu, Laikui;
Zhu, Weiwen

Publication type:

Article

Crosstalk between cancer-associated fibroblasts and regulated cell death in tumors: insights into apoptosis, autophagy, ferroptosis, and pyroptosis.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01958-9

By:

Chen, Cong;
Liu, Jian;
Lin, Xia;
Xiang, Aizhai;
Ye, Qianwei;
Guo, Jufeng;
Rui, Tao;
Xu, Jian;
Hu, Shufang

Publication type:

Article

Increased miR-3074-5p expression promotes M1 polarization and pyroptosis of macrophages via ERα/NLRP3 pathway and induces adverse pregnancy outcomes in mice.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01941-4

By:

Yang, Long;
Xu, Hao-Ran;
Zhang, Xuan;
Shi, Yan;
Shi, Jia-Xin;
Chen, Qian-Qian;
Shen, Xiao-Rong;
He, Ya-Ping;
Tang, Jia-Nan;
Gu, Wen-Wen;
Wang, Jian

Publication type:

Article

Blocking CIRP protects against acute pancreatitis by improving mitochondrial function and suppressing pyroptosis in acinar cells.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01923-6

By:

Liu, Wuming;
Ren, Yifan;
Wang, Tao;
Wang, Mengzhou;
Xu, Yujia;
Zhang, Jia;
Bi, Jianbin;
Wu, Zheng;
Zhang, Yuanyuan;
Wu, Rongqian

Publication type:

Article

Bacillus cereus cereolysin O induces pyroptosis in an undecapeptide-dependent manner.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01887-7

By:

Wang, Yujian;
Luo, Jingchang;
Guan, Xiaolu;
Zhao, Yan;
Sun, Li

Publication type:

Article

IP3R2-mediated Ca<sup>2+</sup> release promotes LPS-induced cardiomyocyte pyroptosis via the activation of NLRP3/Caspase-1/GSDMD pathway.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01840-8

By:

Wu, Qing-Rui;
Yang, Hui;
Zhang, Hui-Dan;
Cai, Yong-Jiang;
Zheng, Yan-Xiang;
Fang, Heng;
Wang, Zi-Fan;
Kuang, Su-Juan;
Rao, Fang;
Huang, Huan-Lei;
Deng, Chun-Yu;
Chen, Chun-Bo

Publication type:

Article