Works about PROTEIN kinase B

Results: 2857

BERBERINE INHIBITS COLON CANCER PROGRESSION THROUGH MIR-181A/PTEN/PI3K/AKT AXIS IN RATS.

Published in:

Acta Poloniae Pharmaceutica, 2025, v. 82, n. 1, p. 155, doi. 10.32383/appdr/203457

By:

CHEN LI;
XU LI

Publication type:

Article

PknB and STP as potential targets of luteolin in combating Trueperella pyogenes infections.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-08698-5

By:

Guo, Yueting;
Su, Hongyu;
Yu, Lihui;
Wang, Yingyu;
Tian, Chunlian;
Zhang, Dexian;
Guo, Yuru;
Liu, Mingchun

Publication type:

Article

LPS pretreated dental follicle stem cell derived exosomes promote periodontal tissue regeneration via miR-184 and PPARα-Akt-JNK signaling pathway.

Published in:

Stem Cell Research & Therapy, 2025, v. 16, n. 1, p. 1, doi. 10.1186/s13287-025-04462-8

By:

Chen, Liangrui;
Zhang, Jiaxiang;
Yu, Jialu;
Guo, Shujuan;
Tian, Weidong

Publication type:

Article

Enhanced effect of the leaves extract from Prunus persica var. nucipersica on antioxidation, collagen synthesis, re-epithelialization and angiogenesis for the improvement of skin wound healing.

Published in:

Biotechnic & Histochemistry, 2025, v. 100, n. 5, p. 279, doi. 10.1080/10520295.2025.2513948

By:

Kim, Joung-Hee;
Choi, Hee-Jung;
Kim, Cheorl-Ho;
Chung, Tae-Wook;
Kim, Keuk-Jun

Publication type:

Article

淫羊藿素对非小细胞肺癌的抑制作用研究.

Published in:

Journal of Modern Medicine & Health, 2025, v. 41, n. 6, p. 1307, doi. 10.3969/j.issn.1009-5519.2025.06.003

By:

马丁丁;
石鑫;
左宏波;
王志;
蒋轶

Publication type:

Article

The Versatile Role of Period Circadian Regulators (PERs) in Oral Squamous Cell Carcinoma.

Published in:

Biocell, 2025, v. 49, n. 6, p. 961, doi. 10.32604/biocell.2025.062918

By:

Huang, Mei;
Zhang, Zhenyu;
Luo, Yuqi;
Wu, Yuqi;
Pan, Dan;
Zhou, Yu;
Luo, Xiaobo;
Jiang, Yuchen

Publication type:

Article

Luteolin Potentially Alleviates Methamphetamine Withdrawal-Induced Negative Emotions and Cognitive Deficits Through the AKT/FOXO1/HO-1 Signaling Pathway in the Prefrontal Cortex and Caudate Putamen.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5739, doi. 10.3390/ijms26125739

By:

Gao, Baoyao;
An, Ran;
Liang, Min;
Wang, Xinglin;
Peng, Jianhang;
Chen, Xingyao;
Liu, Zijun;
Li, Tao;
Liu, Xinshe;
Zhang, Jianbo;
Han, Wei

Publication type:

Article

Correction: Wang et al. Anti-Metabolic Syndrome Effects of Fucoidan from Fucus vesiculosus via Reactive Oxygen Species-Mediated Regulation of JNK, Akt, and AMPK Signaling. Molecules 2019, 24 , 3319.

Published in:

2025

By:

Wang, Xueliang;
Shan, Xindi;
Dun, Yunlou;
Cai, Chao;
Hao, Jiejie;
Li, Guoyun;
Cui, Kaiyun;
Yu, Guangli

Publication type:

Correction Notice

饲料精氨酸对生长中期镜鲤生长及肌肉品质的影响.

Published in:

Journal of Hydrobiology / Shuisheng Shengwu Xuebao, 2025, v. 49, n. 7, p. 1, doi. 10.7541/2025.2024.0363

By:

高一琪;
范泽;
程镇燕;
吴迪;
王连生;
李晋南;
李晨辉

Publication type:

Article

<i>Mycobacterium tuberculosis</i> Ser/Thr Protein Kinase B Mediates an Oxygen-Dependent Replication Switch.

Published in:

PLoS Biology, 2014, v. 12, n. 1, p. 1, doi. 10.1371/journal.pbio.1001746

By:

Ortega, Corrie;
Liao, Reiling;
Anderson, Lindsey N.;
Rustad, Tige;
Ollodart, Anja R.;
Wright, Aaron T.;
Sherman, David R.;
Grundner, Christoph

Publication type:

Article

Antifibrotic effects of luteolin on hepatic stellate cells and liver fibrosis by targeting AKT/ mTOR/p70S6K and TGFβ/Smad signalling pathways.

Published in:

Liver International, 2015, v. 35, n. 4, p. 1222, doi. 10.1111/liv.12638

By:

Li, Jie;
Li, Xingxia;
Xu, Weiheng;
Wang, Shaozhan;
Hu, Zhenlin;
Zhang, Qing;
Deng, Xing;
Wang, Jing;
Zhang, Junping;
Guo, Cheng

Publication type:

Article

The role of AKT isoforms in glioblastoma: AKT3 delays tumor progression.

Published in:

Journal of Neuro-Oncology, 2016, v. 130, n. 1, p. 43, doi. 10.1007/s11060-016-2220-z

By:

Joy, Anna;
Kapoor, Manisha;
Georges, Joseph;
Butler, Lacy;
Chang, Yongchang;
Li, Chaokun;
Crouch, Acacia;
Smirnov, Ivan;
Nakada, Mitsitoshi;
Hepler, James;
Marty, Max;
Feuerstein, Burt

Publication type:

Article

Mst1 regulates glioma cell proliferation via the AKT/mTOR signaling pathway.

Published in:

Journal of Neuro-Oncology, 2015, v. 121, n. 2, p. 279, doi. 10.1007/s11060-014-1654-4

By:

Chao, Yuewen;
Wang, Yan;
Liu, Xuejiao;
Ma, Peng;
Shi, Yi;
Gao, Jian;
Shi, Qiong;
Hu, Jinxia;
Yu, Rutong;
Zhou, Xiuping

Publication type:

Article

Phosphorylation of AKT induced by phosphorylated Hsp27 confers the apoptosis-resistance in t-AUCB-treated glioblastoma cells in vitro.

Published in:

Journal of Neuro-Oncology, 2015, v. 121, n. 1, p. 83, doi. 10.1007/s11060-014-1610-3

By:

Li, Rujun;
Li, Junyang;
Sang, Dongping;
Lan, Qing

Publication type:

Article

Harmine hydrochloride inhibits Akt phosphorylation and depletes the pool of cancer stem-like cells of glioblastoma.

Published in:

Journal of Neuro-Oncology, 2013, v. 112, n. 1, p. 39, doi. 10.1007/s11060-012-1034-x

By:

Liu, Huailei;
Han, Dayong;
Liu, Yaohua;
Hou, Xu;
Wu, Jianing;
Li, Huadong;
Yang, Jie;
Shen, Chen;
Yang, Guang;
Fu, Changyu;
Li, Xianfeng;
Che, Hui;
Ai, Jing;
Zhao, Shiguang

Publication type:

Article

In vitro facilitating role of polygonatum sibiricum polysaccharide in osteogenic differentiation of bone marrow mesenchymal stem cells from patients with multiple myeloma.

Published in:

Biotechnology Letters, 2021, v. 43, n. 7, p. 1311, doi. 10.1007/s10529-021-03125-x

By:

Zhao, Jianqiang;
Ma, Lijie;
Ni, Zengfeng;
Liu, Hui

Publication type:

Article

Vitamin D3 Exerts a Neuroprotective Effect in Metabolic Syndrome Rats: Role of BDNF/TRKB/Akt/GS3Kβ Pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 12, p. 1, doi. 10.1002/jbt.70082

By:

Aladdin, Noha;
Ghareib, Salah A.

Publication type:

Article

PKN2 Promotes Peripheral Nerve Repair by Regulating Autophagy via Activation of the AKT‐mTOR Pathway: An In Vitro Study.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 12, p. 1, doi. 10.1002/jbt.70063

By:

Wang, Lin;
Huang, Yuan‐sheng

Publication type:

Article

Sinensetin inhibits the movement ability and tumor immune microenvironment of non‐small cell lung cancer through the inactivation of AKT/β‐catenin axis.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 11, p. 1, doi. 10.1002/jbt.70024

By:

Shi, Zhenliang;
Shen, Yimeng;
Liu, Xin;
Zhang, Sipei

Publication type:

Article

THF induces apoptosis by downregulating initiation, promotion, and progression phase biomarkers in skin and lung carcinoma.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 9, p. 1, doi. 10.1002/jbt.23838

By:

Raza, Waseem;
Meena, Abha;
Luqman, Suaib

Publication type:

Article

Unveiling myricetin's pharmacological potency: A comprehensive exploration of the molecular pathways with special focus on PI3K/AKT and Nrf2 signaling.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 6, p. 1, doi. 10.1002/jbt.23739

By:

Goyal, Ahsas;
Sikarwar, Om;
Verma, Aanchal;
Solanki, Kunal;
Agrawal, Neetu;
Dubey, Nandini;
Yadav, Harlokesh Narayan

Publication type:

Article

Curcumin affects autophagy of prolactinoma cells by upregulating miR‐206 to exert antitumor effects.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 6, p. 1, doi. 10.1002/jbt.23734

By:

Duan, Jia‐feng;
Zhang, Qiu‐juan;
Zhu, Jin;
Lu, Jia‐hui

Publication type:

Article

The progression of obstructive renal fibrosis in rats is regulated by ADAMTS18 gene methylation in the embryonic kidney through the AKT/Notch pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 1, p. 1, doi. 10.1002/jbt.23628

By:

Xu, Ben;
Zhang, Jia‐en;
Ye, Lin;
Yuan, Chang‐wei

Publication type:

Article

Wogonin inhibits hepatoma cell proliferation by targeting miR‐27b‐5p/YWHAZ axis.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 12, p. 1, doi. 10.1002/jbt.23508

By:

Ma, Ming‐Yue;
Wang, Qian;
Wang, Shou‐Mei;
Feng, Xiao‐Jun;
Xian, Zhi‐Hong;
Zhang, Shu‐Hui

Publication type:

Article

Evaluating the effect of ginsenoside Rg1 on CPF‐induced brain injury in mice via PI3k/AKT pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 5, p. 1, doi. 10.1002/jbt.23319

By:

Liu, Silu;
Pei, Hongyan;
Chen, Weijia;
Zhu, Xiaoying;
Wang, Yu;
Li, Jianming;
He, Zhongmei;
Du, Rui

Publication type:

Article

Dieckol, a natural polyphenolic drug, inhibits the proliferation and migration of colon cancer cells by inhibiting PI3K, AKT, and mTOR phosphorylation.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 5, p. 1, doi. 10.1002/jbt.23313

By:

Dai, Wei;
Dai, Yong gang;
Ren, Dong feng;
Zhu, Da wei

Publication type:

Article

Exploring the cardioprotective effects of canagliflozin against cisplatin‐induced cardiotoxicity: Role of iNOS/NF‐κB, Nrf2, and Bax/cytochrome C/Bcl‐2 signals.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 4, p. 1, doi. 10.1002/jbt.23309

By:

Ali, Fares E. M.;
Hassanein, Emad H. M.;
Abd El‐Ghafar, Omnia A. M.;
Rashwan, Eman K.;
Saleh, Fayez M.;
Atwa, Ahmed M.

Publication type:

Article

MiR‐146a‐5p accelerates sepsis through dendritic cell activation and glycolysis via targeting ATG7.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 10, p. 1, doi. 10.1002/jbt.23151

By:

Yu, Junbo;
Xue, Jianhua;
Liu, Chun;
Zhang, Aixian;
Qin, Lili;
Liu, Jiajia;
Yang, Yang

Publication type:

Article

Bergapten mediated inflammatory and apoptosis through AMPK/eNOS/AKT signaling pathway of isoproterenol‐induced myocardial infarction in Wistar rats.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 9, p. 1, doi. 10.1002/jbt.23143

By:

Yang, Yanni;
Han, Juanping;
Lilly, Renju G.;
Yang, Qin;
Guo, Yanjie

Publication type:

Article

Dioscin exhibits protective effects on in vivo and in vitro asthma models via suppressing TGF‐β1/Smad2/3 and AKT pathways.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 8, p. 1, doi. 10.1002/jbt.23084

By:

Shang, Qian;
Zhu, Li;
Shang, Weina;
Zeng, Jia;
Qi, Yong

Publication type:

Article

Inhibition of MAC30 exerts antitumor effects in nasopharyngeal carcinoma via affecting the Akt/GSK‐3β/β‐catenin pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 7, p. 1, doi. 10.1002/jbt.23061

By:

Zhang, Pengfei;
Tian, Qi;
Gao, Huan;
Zhao, Andi;
Shao, Yuan;
Yang, Jin

Publication type:

Article

W436, a novel SMART derivative, exhibits anti‐hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 8, p. 1, doi. 10.1002/jbt.22831

By:

Man, Shuai;
Wu, Zhuzhu;
Sun, Rui;
Guan, Qi;
Li, Zengqiang;
Zuo, Daiying;
Zhang, Weige;
Wu, Yingliang

Publication type:

Article

Exaggerated activities of TRPM7 underlie bupivacaine‐induced neurotoxicity in the SH‐SY5Y cells preconditioned with high glucose.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 8, p. 1, doi. 10.1002/jbt.22826

By:

Dai, Shuang‐Hua;
Li, Ya‐Wen;
Hong, Qing‐Xiong;
Su, Tao;
Xu, Shi‐Yuan

Publication type:

Article

Syringic acid regulates suppression of the STAT3/JNK/AKT pathway via inhibition of human ovarian teratoma cancer cell (PA‐1) growth—in vitro study.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 6, p. 1, doi. 10.1002/jbt.22776

By:

Yang, Lina;
Qu, Changhong;
Jin, Jiaxi;
Yang, Hong;
Pei, Lipeng

Publication type:

Article

Piperlongumine attenuates oxidative stress, inflammatory, and apoptosis through modulating the GLUT‐2/4 and AKT signaling pathway in streptozotocin‐induced diabetic rats.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 6, p. 1, doi. 10.1002/jbt.22763

By:

Xu, Ping;
Xiao, Juan;
Chi, Shuixia

Publication type:

Article

Activation of Akt‐dependent Nrf2/ARE pathway by restoration of Brg‐1 remits high glucose‐induced oxidative stress and ECM accumulation in podocytes.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 3, p. 1, doi. 10.1002/jbt.22672

By:

Yan, Hao;
Xu, Fei;
Xu, Jun;
Song, Ming‐Ai;
Wang, Kai;
Wang, Lulu

Publication type:

Article

Deoxyshikonin inhibits cisplatin resistance of non–small‐cell lung cancer cells by repressing Akt‐mediated ABCB1 expression and function.

Published in:

Journal of Biochemical & Molecular Toxicology, 2020, v. 34, n. 10, p. 1, doi. 10.1002/jbt.22560

By:

Zhang, Suhong;
Wang, Yi

Publication type:

Article

ROS accumulation contributes to abamectin‐induced apoptosis and autophagy via the inactivation of PI3K/AKT/mTOR pathway in TM3 Leydig cells.

Published in:

Journal of Biochemical & Molecular Toxicology, 2020, v. 34, n. 8, p. 1, doi. 10.1002/jbt.22505

By:

Zhu, Shanshan;
Zhou, Jing;
Sun, Xiaoyu;
Zhou, Zhonglou;
Zhu, Qiqi

Publication type:

Article

Galectin‐3 mediates pulmonary vascular endothelial cell dynamics via TRPC1/4 under acute hypoxia.

Published in:

Journal of Biochemical & Molecular Toxicology, 2020, v. 34, n. 5, p. 1, doi. 10.1002/jbt.22463

By:

Li, Yumei;
Chen, Xinghe;
Zeng, Xixi;
Chen, Shaokun;
Yang, Xi;
Zhang, Li

Publication type:

Article

MEG3 is restored by schisandrin A and represses tumor growth in choriocarcinoma cells.

Published in:

Journal of Biochemical & Molecular Toxicology, 2020, v. 34, n. 4, p. 1, doi. 10.1002/jbt.22455

By:

Ji, Li;
Ma, Li

Publication type:

Article

Circular RNA circHIAT1 inhibits proliferation and epithelial‐mesenchymal transition of gastric cancer cell lines through downregulation of miR‐21.

Published in:

Journal of Biochemical & Molecular Toxicology, 2020, v. 34, n. 4, p. 1, doi. 10.1002/jbt.22458

By:

Quan, Jingzi;
Dong, Dongfang;
Lun, Yue;
Sun, Bo;
Sun, Haiyuan;
Wang, Qunying;
Yuan, Gang

Publication type:

Article

Anti‐inflammatory effects of doxepin hydrochloride against LPS‐induced C6‐glioma cell inflammatory reaction by PI3K‐mediated Akt signaling.

Published in:

Journal of Biochemical & Molecular Toxicology, 2020, v. 34, n. 2, p. N.PAG, doi. 10.1002/jbt.22424

By:

Tao, Feng;
Zhu, Jie;
Duan, Lijie;
Wu, Junfeng;
Zhang, Jianfeng;
Yao, Kai;
Bo, Jimei;
Zu, Hengbing

Publication type:

Article

Correlation between serum cysteine-rich protein 61 and disease activity of antineutrophil cytoplasmic antibody–associated vasculitis.

Published in:

Clinical Rheumatology, 2021, v. 40, n. 9, p. 3703, doi. 10.1007/s10067-021-05701-y

By:

Yoon, Taejun;
Ahn, Sung Soo;
Pyo, Jung Yoon;
Lee, Lucy Eunju;
Song, Jason Jungsik;
Park, Yong-Beom;
Lee, Sang-Won

Publication type:

Article

Propranolol inhibits the activity of PI3K, AKT, and HIF-1α in infantile hemangiomas.

Published in:

2018

By:

Lin, Zhenying;
Wang, Luanhong;
Huang, Guang;
Wang, Wenyan;
Lin, Han

Publication type:

journal article

Comparative analysis of hepatic miRNA levels in male marathon mice reveals a link between obesity and endurance exercise capacities.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2016, v. 186, n. 8, p. 1067, doi. 10.1007/s00360-016-1006-0

By:

Ohde, Daniela;
Brenmoehl, Julia;
Walz, Christina;
Wirthgen, Elisa;
Hoeflich, Andreas;
Tuchscherer, Armin

Publication type:

Article

Intraarticular gene transfer of SPRY2 suppresses adjuvant-induced arthritis in rats.

Published in:

Applied Microbiology & Biotechnology, 2015, v. 99, n. 16, p. 6727, doi. 10.1007/s00253-015-6618-x

By:

Zhang, Wei;
Zhu, Jingying;
Du, Zhiyan;
Yu, Jiyun;
Xu, Yuanji;
Wang, Fang

Publication type:

Article

Antagonistic Effects of Insulin and TGF-β3 during Chondrogenic Differentiation of Human BMSCs under a Minimal Amount of Factors.

Published in:

Cells Tissues Organs, 2016, v. 201, n. 2, p. 188, doi. 10.1159/000442411

By:

Satoshi Hara, Emilio;
Mitsuaki Ono;
Yuya Yoshioka;
Junji Ueda;
Yuri Hazehara;
Hai Thanh Pham;
Takuya Matsumoto;
Takuo Kuboki

Publication type:

Article

A proline-rich loop mediates specific functions of human sialidase NEU4 in SK-N-BE neuronal differentiation.

Published in:

Glycobiology, 2013, v. 23, n. 12, p. 1499, doi. 10.1093/glycob/cwt078

By:

Bigi, Alessandra;
Tringali, Cristina;
Forcella, Matilde;
Mozzi, Alessandra;
Venerando, Bruno;
Monti, Eugenio;
Fusi, Paola

Publication type:

Article

Isorhamnetin inhibits cholangiocarcinoma proliferation and metastasis via PI3K/AKT signaling pathway.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02217-8

By:

Tan, Zhiguo;
Liu, Jie;
Hou, Min;
Zhou, Jia;
chen, Yu;
Chen, Xu;
Leng, Yufang

Publication type:

Article

Anti-inflammatory Effects of Ceramides from Incarvillea compacta.

Published in:

Modern Food Science & Technology, 2022, v. 38, n. 11, p. 46, doi. 10.13982/j.mfst.1673-9078.2022.11.1416

By:

SONG Chao;
GUAN Xueting;
YUAN Qiaoyun;
HE Yang;
ZHANG Ji;
HU Weicheng

Publication type:

Article