Works about PROGRANULIN

Results: 378

Higher levels of progranulin in cerebrospinal fluid of patients with lymphoma and carcinoma with CNS metastasis.

Published in:

Journal of Neuro-Oncology, 2018, v. 137, n. 3, p. 455, doi. 10.1007/s11060-017-2742-z

By:

Kimura, Akio;
Takemura, Masao;
Serrero, Ginette;
Yoshikura, Nobuaki;
Hayashi, Yuichi;
Saito, Kuniaki;
Inuzuka, Takashi

Publication type:

Article

Progranulin correlated with rapid progressive interstitial lung disease in dermatomyositis with anti-melanoma differentiation-associated gene 5 antibody.

Published in:

Clinical Rheumatology, 2022, v. 41, n. 3, p. 757, doi. 10.1007/s10067-021-05816-2

By:

Shanshan, Li;
Yamei, Zhang;
Ling, Zhang;
Xin, Lu;
Guochun, Wang

Publication type:

Article

Serum progranulin levels in Hispanic rheumatoid arthritis patients treated with TNF antagonists: a prospective, observational study.

Published in:

Clinical Rheumatology, 2017, v. 36, n. 3, p. 507, doi. 10.1007/s10067-016-3467-7

By:

Johnson, Jennifer;
Yeter, Karen;
Rajbhandary, Rosy;
Neal, Rebekah;
Tian, Qingyun;
Jian, Jinlong;
Fadle, Natalie;
Thurner, Lorenz;
Liu, Chuanju;
Stohl, William

Publication type:

Article

Early-Phase Trial Launches of VES001 for Gene-Related Frontotemporal Dementia.

Published in:: Patient Care (Online), 2025, p. 7
Publication type:: Article

Evaluation of progranulin and inflammatory markers in the diagnosis of acute cholecystitis.

Published in:

Medicine Science, 2024, v. 13, n. 3, p. 469, doi. 10.5455/medscience.2024.06.059

By:

Kilci, Ali Ihsan;
Seyithanoglu, Muhammed;
Kaya, Erhan;
Hakkoymaz, Hakan;
Gedik, Muhammed Semih;
Kucuk, Omer Faruk

Publication type:

Article

Study of serum progranulin level and its relation to microvascular complications in subjects with type 1 diabetes mellitus.

Published in:

Clinical Diabetology, 2021, v. 10, n. 6, p. 1, doi. 10.5603/DK.a2021.0009

By:

Rohoma, Kamel;
Souka, Mabaheg;
Elsayed, Eman;
Mohamed, Shaimaa;
Fathalla, Reem Mahmoud

Publication type:

Article

Soluble PCSK9 Inhibition: Indications, Clinical Impact, New Molecular Insights and Practical Approach—Where Do We Stand?

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 8, p. 2922, doi. 10.3390/jcm12082922

By:

Bellino, Michele;
Galasso, Gennaro;
Silverio, Angelo;
Tedeschi, Michele;
Formisano, Ciro;
Romei, Stefano;
Esposito, Luca;
Cancro, Francesco Paolo;
Vassallo, Maria Giovanna;
Accarino, Giulio;
Verdoia, Monica;
Di Muro, Francesca Maria;
Vecchione, Carmine;
De Luca, Giuseppe

Publication type:

Article

Progranulin Deficiency Induces Mitochondrial Dysfunction in Frontotemporal Lobar Degeneration with TDP-43 Inclusions.

Published in:

Antioxidants, 2023, v. 12, n. 3, p. 581, doi. 10.3390/antiox12030581

By:

Rodríguez-Periñán, Guiomar;
de la Encarnación, Ana;
Moreno, Fermín;
López de Munain, Adolfo;
Martínez, Ana;
Martín-Requero, Ángeles;
Alquézar, Carolina;
Bartolomé, Fernando

Publication type:

Article

PGRN protects against colitis progression in mice in an IL-10 and TNFR2 dependent manner.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep07023

By:

Fanhua Wei;
Yuying Zhang;
Jinlong Jian;
Mundra, Jyoti Joshi;
Qingyun Tian;
Jiqiang Lin;
Lafaille, Juan Jose;
Wei Tang;
Weiming Zhao;
Xiuping Yu;
Chuan-Ju Liu

Publication type:

Article

Progranulin and Activin A Concentrations are Elevated in Serum from Patients with Acute Exacerbations of Idiopathic Pulmonary Fibrosis.

Published in:

Lung (0341-2040), 2021, v. 199, n. 5, p. 467, doi. 10.1007/s00408-021-00470-6

By:

Xie, Tian;
Han, Lizhen;
Chen, Yongxing;
Wu, Haihong

Publication type:

Article

The Role of CTGF in Inflammatory Responses Induced by Silica Particles in Human Bronchial Epithelial Cells.

Published in:

Lung (0341-2040), 2019, v. 197, n. 6, p. 783, doi. 10.1007/s00408-019-00272-x

By:

Zhou, Ting;
Yu, Qimei;
Lin, Hui;
Wang, Zhenyu;
Fu, Guoqing;
Lei, Lu;
Shi, Yuqin;
Zhang, Ling;
Qin, Lingzhi;
Liu, Yuewei

Publication type:

Article

CNS-wide repopulation by hematopoietic-derived microglia-like cells corrects progranulin deficiency in mice.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49908-4

By:

Colella, Pasqualina;
Sayana, Ruhi;
Suarez-Nieto, Maria Valentina;
Sarno, Jolanda;
Nyame, Kwamina;
Xiong, Jian;
Pimentel Vera, Luisa Natalia;
Arozqueta Basurto, Jessica;
Corbo, Marco;
Limaye, Anay;
Davis, Kara L.;
Abu-Remaileh, Monther;
Gomez-Ospina, Natalia

Publication type:

Article

Relationship of progranulin response with some physio-biochemical parameters in Akkaraman sheep.

Published in:

Pakistan Journal of Agricultural Sciences, 2023, v. 60, n. 4, p. 643, doi. 10.21162/PAKJAS/23.223

By:

Bayraktar, Bülent;
Tekce, Emre;
Genç, Murat;
Kaya, Hacer;
Özcan, Gülbahar Böyük;
Aydemir, Şeyma;
Kotan, Gökşad Cemil;
Takma, Çiğdem;
Ürüşan, Hilal;
Aksakal, Vecihi;
Paksoy, Zahid;
Atalay, Banu;
Laçin, Burak Batuhan;
Toprak, Burhan;
Ülker, Ufuk

Publication type:

Article

Progranulin protects the mouse retina under hypoxic conditions via inhibition of the Toll-like receptor-4-NADPH oxidase 4 signaling pathway.

Published in:

Molecular Medicine Reports, 2019, v. 19, n. 1, p. 382

By:

You, Zhi-Peng;
Yu, Meng-Jia;
Zhang, Yu-Lan;
Shi, Ke

Publication type:

Article

Clinical implications of progranulin in gastric cancer and its regulation via a positive feedback loop involving AKT and ERK signaling pathways.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 6, p. 9685, doi. 10.3892/mmr.2017.7796

By:

DONG YANG;
RUIDONG LI;
HUILI WANG;
JUNYE WANG;
LEI HAN;
LIHUA PAN;
XUEQIN LI;
QINGLI KONG;
GUIJUAN WANG;
XIUJUN SU

Publication type:

Article

MicroRNA-588 suppresses tumor cell migration and invasion by targeting GRN in lung squamous cell carcinoma.

Published in:

Molecular Medicine Reports, 2016, v. 14, n. 4, p. 3021, doi. 10.3892/mmr.2016.5643

By:

LI QIAN;
LONGLONG LIN;
YUFENG DU;
XIAOYAN HAO;
YUZE ZHAO;
XUEJUN LIU

Publication type:

Article

Effects of hypoxia on progranulin expression in HT22 mouse hippocampal cells.

Published in:

Molecular Medicine Reports, 2014, v. 9, n. 5, p. 1675, doi. 10.3892/mmr.2014.2016

By:

LI LUO;
LANHAI LU;
YINGHONG LU;
LIHONG ZHANG;
BOFEI LI;
KAIHUA GUO;
LIZHI CHEN;
YANG WANG;
YIJIA SHAO;
JIE XU

Publication type:

Article

Progranulin expression in neural stem cells and their differentiated cell lineages: An immunocytochemical study.

Published in:

Molecular Medicine Reports, 2013, v. 8, n. 5, p. 1359, doi. 10.3892/mmr.2013.1664

By:

LANHAI LÜ;
LI LUO;
YINGHONG LU;
LIZHI CHEN;
JIE XU;
KAIHUA GUO

Publication type:

Article

The role of progranulin in diabetes and kidney disease.

Published in:

Diabetology & Metabolic Syndrome, 2015, v. 7, p. 1, doi. 10.1186/s13098-015-0112-6

By:

Nicoletto, Bruna Bellincanta;
Canani, Luis Henrique

Publication type:

Article

Elevation of the Plasma Levels of TNF Receptor 2 in Association with Those of CD25, OX40, and IL-10 and HTLV-1 Proviral Load in Acute Adult T-Cell Leukemia.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 4, p. N.PAG, doi. 10.3390/v14040751

By:

Kato, Megumi;
Imaizumi, Naoki;
Tanaka, Reiko;
Mizuguchi, Mariko;
Hayashi, Masaki;
Miyagi, Takashi;
Uchihara, Junnosuke;
Ohshiro, Kazuiku;
Todoroki, Junpei;
Karube, Kennosuke;
Masuzaki, Hiroaki;
Tanaka, Yuetsu;
Fukushima, Takuya

Publication type:

Article

Targeting nonsense-mediated RNA decay does not increase progranulin levels in the Grn<sup>R493X</sup> mouse model of frontotemporal dementia.

Published in:

PLoS ONE, 2023, v. 18, n. 3, p. 1, doi. 10.1371/journal.pone.0282822

By:

Smith, Denise M.;
Niehoff, Michael L.;
Ling, Karen;
Jafar-Nejad, Paymaan;
Rigo, Frank;
Farr, Susan A.;
Wilkinson, Miles F.;
Nguyen, Andrew D.

Publication type:

Article

Serum progranulin is not associated with rs5848 polymorphism in Korean patients with neurodegenerative diseases.

Published in:

PLoS ONE, 2022, v. 17, n. 1, p. 1, doi. 10.1371/journal.pone.0261007

By:

Jung, Na-Yeon;
Kim, Hyang-Sook;
Kim, Eun Soo;
Jeon, Sumin;
Lee, Myung Jun;
Pak, Kyoungjune;
Lee, Jae-Hyeok;
Lee, Young Min;
Lee, Kangyoon;
Shin, Jin-Hong;
Ko, Jun Kyeung;
Lee, Jae Meen;
Yoon, Jin A.;
Hwang, Chungsu;
Choi, Kyung-Un;
Huh, Gi Yeong;
Kim, Young-Eun;
Kim, Eun-Joo

Publication type:

Article

Progranulin Promotes Regeneration of Inflammatory Periodontal Bone Defect in Rats via Anti-inflammation, Osteoclastogenic Inhibition, and Osteogenic Promotion.

Published in:

Inflammation, 2019, v. 42, n. 1, p. 221, doi. 10.1007/s10753-018-0886-4

By:

Chen, Qian;
Cai, Jun;
Li, Xiao;
Song, Aimei;
Guo, Hongmei;
Sun, Qinfeng;
Yang, Chengzhe;
Yang, Pishan

Publication type:

Article

Progranulin Is Positively Associated with Intervertebral Disc Degeneration by Interaction with IL-10 and IL-17 Through TNF Pathways.

Published in:

Inflammation, 2018, v. 41, n. 5, p. 1852, doi. 10.1007/s10753-018-0828-1

By:

Wang, Shaoyi;
Wei, Jianlu;
Fan, Yuchen;
Ding, Hong;
Tian, Huichao;
Zhou, Xiaocong;
Cheng, Lei

Publication type:

Article

Progranulin Protects Against Osteonecrosis of the Femoral Head by Activating ERK1/2 Pathway.

Published in:

Inflammation, 2017, v. 40, n. 3, p. 946, doi. 10.1007/s10753-017-0539-z

By:

Han, Yingguang;
Si, Meng;
Zhao, Yunpeng;
Liu, Yi;
Cheng, Kaiyuan;
Zhang, Yuedong;
Jia, Jialin;
Li, Jingkun;
Nie, Lin

Publication type:

Article

PGRN Suppresses Inflammation and Promotes Autophagy in Keratinocytes Through the Wnt/β-Catenin Signaling Pathway.

Published in:

Inflammation, 2016, v. 39, n. 4, p. 1387, doi. 10.1007/s10753-016-0370-y

By:

Tian, Rong;
Li, You;
Yao, Xu

Publication type:

Article

Increased Serum GP88 (Progranulin) Concentrations in Rheumatoid Arthritis.

Published in:

Inflammation, 2014, v. 37, n. 5, p. 1806, doi. 10.1007/s10753-014-9911-4

By:

Yamamoto, Yasuko;
Takemura, Masao;
Serrero, Ginette;
Hayashi, Jun;
Yue, Binbin;
Tsuboi, Aya;
Kubo, Hisako;
Mitsuhashi, Takashi;
Mannami, Kenji;
Sato, Masao;
Matsunami, Hidetoshi;
Matuo, Yushi;
Saito, Kuniaki

Publication type:

Article

Anti-sortilin1 Antibody Up-Regulates Progranulin via Sortilin1 Down-Regulation.

Published in:

Frontiers in Neuroscience, 2020, v. 11, p. N.PAG, doi. 10.3389/fnins.2020.586107

By:

Miyakawa, Shuuichi;
Sakuma, Hiroyuki;
Warude, Dnyaneshwar;
Asanuma, Satomi;
Arimura, Naoto;
Yoshihara, Tomoki;
Tavares, Daniel;
Hata, Akito;
Ida, Koh;
Hori, Yuri;
Okuzono, Yuumi;
Yamamoto, Syunsuke;
Iida, Koichi;
Shimizu, Hisao;
Kondo, Shinichi;
Sato, Shuji

Publication type:

Article

Progranulin Adsorbs to Polypropylene Tubes and Disrupts Functional Assays: Implications for Research, Biomarker Studies, and Therapeutics.

Published in:

Frontiers in Neuroscience, 2020, v. 11, p. N.PAG, doi. 10.3389/fnins.2020.602235

By:

Gururaj, Sushmitha;
Sampognaro, Paul J.;
Argouarch, Andrea R.;
Kao, Aimee W.

Publication type:

Article

Progranulin is highly expressed in patients with chronic periodontitis and protects against experimental periodontitis in rats.

Published in:

2018

By:

Li, Xiao;
Zuo, Zhibin;
Chen, Qian;
Li, Jing;
Tang, Wei;
Yang, Pishan

Publication type:

journal article

Progranulin Inhibits Human T Lymphocyte Proliferation by Inducing the Formation of Regulatory T Lymphocytes.

Published in:

Mediators of Inflammation, 2017, p. 1, doi. 10.1155/2017/7682083

By:

Kwack, Kyu Hwan;
Lee, Hyeon-Woo

Publication type:

Article

Role of Serum Progranulin as a Biological Marker in SLE Patients.

Published in:

QJM: An International Journal of Medicine, 2024, v. 117, p. i70, doi. 10.1093/qjmed/hcae070.159

By:

Zeitoun, Yasser Ahmed;
Soliman, Dina Ahmed;
Gamal, Dalia Mohamed;
Attia, Mirette Eskander;
Wahba, Nancy Samir

Publication type:

Article

Progranulin Gene Therapy Improves Lysosomal Dysfunction and Microglial Pathology Associated with Frontotemporal Dementia and Neuronal Ceroid Lipofuscinosis.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 9, p. 2341, doi. 10.1523/JNEUROSCI.3081-17.2018

By:

Arrant, Andrew E.;
Onyilo, Vincent C.;
Unger, Daniel E.;
Roberson, Erik D.

Publication type:

Article

The Progranulin Cleavage Products, Granulins, Exacerbate TDP-43 Toxicity and Increase TDP-43 Levels.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 25, p. 9315, doi. 10.1523/JNEUROSCI.4808-14.2015

By:

Salazar, Dominique A.;
Butler, Victoria J.;
Argouarch, Andrea R.;
Tsung-Yuan Hsu;
Mason, Amanda;
Ayumi Nakamura;
McCurdy, Helen;
Cox, David;
Ng, Rachel;
Pan, Gloria;
Seeley, William W.;
Miller, Bruce L.;
Kao, Aimee W.

Publication type:

Article

Female-Specific Role of Progranulin to Suppress Bone Formation.

Published in:

Endocrinology, 2019, v. 160, n. 9, p. 2024, doi. 10.1210/en.2018-00842

By:

Wang, Liping;
Roth, Theresa;
Nakamura, Mary C;
Nissenson, Robert A

Publication type:

Article

Recurrent generalized seizures, visual loss, and palinopsia as phenotypic features of neuronal ceroid lipofuscinosis due to progranulin gene mutation.

Published in:

Epilepsia (Series 4), 2014, v. 55, n. 6, p. e56, doi. 10.1111/epi.12632

By:

Canafoglia, Laura;
Morbin, Michela;
Scaioli, Vidmer;
Pareyson, Davide;
D'Incerti, Ludovico;
Fugnanesi, Valeria;
Tagliavini, Fabrizio;
Berkovic, Samuel F.;
Franceschetti, Silvana

Publication type:

Article

Progranulin aggravates lethal Candida albicans sepsis by regulating inflammatory response and antifungal immunity.

Published in:

PLoS Pathogens, 2022, v. 18, n. 9, p. 1, doi. 10.1371/journal.ppat.1010873

By:

Liu, Jiayu;
Lai, Xiaofei;
Yu, Renlin;
Ding, Hao;
Bai, Haobo;
Yang, Zhubin;
Yin, Yibing;
Xu, Fang;
Cao, Ju

Publication type:

Article

Age- and stress-associated C. elegans granulins impair lysosomal function and induce a compensatory HLH-30/TFEB transcriptional response.

Published in:

PLoS Genetics, 2019, v. 15, n. 8, p. 1, doi. 10.1371/journal.pgen.1008295

By:

Butler, Victoria J.;
Gao, Fuying;
Corrales, Christian I.;
Cortopassi, Wilian A.;
Caballero, Benjamin;
Vohra, Mihir;
Ashrafi, Kaveh;
Cuervo, Ana Maria;
Jacobson, Matthew P.;
Coppola, Giovanni;
Kao, Aimee W.

Publication type:

Article

High Serum Progranulin Levels in COVID-19 Patients: A Pilot Study.

Published in:

Biochemistry (00062979), 2022, v. 87, n. 3, p. 207, doi. 10.1134/S0006297922030026

By:

Özgeriş, Fatma B.;
Koçak, Ömer F.;
Kurt, Nezahat;
Parlak, Emine;
Yüce, Neslihan;
Keleş, Mevlüt S.

Publication type:

Article

CORRELATION STUDY OF OBESTATIN AND PROGRANULIN WITH LIVER FUNCTION ENZYME IN IRAQI FEMALES PATIENTS WITH COLORECTAL CANCER.

Published in:

Plant Archives (09725210), 2020, v. 20, n. 2, p. 2412

By:

AL-Sa'adsi, Warka'a T.;
ALTaie, A. F.;
Shabil, Forat Yahya Mohsin

Publication type:

Article

CORRELATION STUDY OF OBESTATIN AND PROGRANULIN WITH LIVER FUNCTION ENZYME IN IRAQI FEMALES PATIENTS WITH COLORECTAL CANCER.

Published in:

Plant Archives (09725210), 2020, v. 20, n. 1, p. 2412

By:

AL-Sa'adsi, Warka'a T.;
ALTaie, A. F.;
Mohsin Shabil, Forat Yahya

Publication type:

Article

Progranulin expression in bleomycin-induced pulmonary fibrosis in mice.

Published in:

Journal of Hainan Medical University, 2024, v. 30, n. 5, p. 337, doi. 10.13210/j.cnki.jhmu.20240004.001

By:

LIU Jieting;
ZHANG Lei;
ZHAO Jie;
XIE Tian

Publication type:

Article

Progranulin gene ( GRN) promoter methylation is increased in patients with sporadic frontotemporal lobar degeneration.

Published in:

Neurological Sciences, 2013, v. 34, n. 6, p. 899, doi. 10.1007/s10072-012-1151-5

By:

Galimberti, Daniela;
D'Addario, Claudio;
Dell'Osso, Bernardo;
Fenoglio, Chiara;
Marcone, Alessandra;
Cerami, Chiara;
Cappa, Stefano;
Palazzo, M.;
Arosio, Beatrice;
Mari, Daniela;
Maccarrone, Mauro;
Bresolin, Nereo;
Altamura, A.;
Scarpini, Elio

Publication type:

Article

Prevalence of frontotemporal lobar degeneration in an isolated population: the Vallecamonica study.

Published in:

Neurological Sciences, 2012, v. 33, n. 4, p. 899, doi. 10.1007/s10072-011-0865-0

By:

Gilberti, Nicola;
Turla, Marinella;
Alberici, Antonella;
Bertasi, Valeria;
Civelli, Patrizia;
Archetti, Silvana;
Padovani, Alessandro;
Borroni, Barbara

Publication type:

Article

A progranulin mutation associated with cortico-basal syndrome in an Italian family expressing different phenotypes of fronto-temporal lobar degeneration.

Published in:

Neurological Sciences, 2012, v. 33, n. 1, p. 93, doi. 10.1007/s10072-011-0655-8

By:

Coppola, Cinzia;
Rossi, Giacomina;
Barbarulo, Anna;
Di Fede, Giuseppe;
Foglia, Carolina;
Piccoli, Elena;
Piscosquito, Giuseppe;
Saracino, Dario;
Tagliavini, Fabrizio;
Cotrufo, Roberto

Publication type:

Article

Inflammatory Biomarkers and Lipid Parameters May Predict an Increased Risk for Atrial Arrhythmias in Patients with Systemic Sclerosis.

Published in:

Biomedicines, 2025, v. 13, n. 1, p. 220, doi. 10.3390/biomedicines13010220

By:

Sebestyén, Veronika;
Ujvárosy, Dóra;
Ratku, Balázs;
Lőrincz, Hajnalka;
Csiha, Sára;
Tari, Dóra;
Majai, Gyöngyike;
Somodi, Sándor;
Szűcs, Gabriella;
Harangi, Mariann;
Szabó, Zoltán

Publication type:

Article

Plasma Levels of Proprotein Convertase Subtilisin/Kexin Type 9 Are Inversely Associated with N-Terminal Pro B-Type Natriuretic Peptide in Older Men and Women.

Published in:

Biomedicines, 2022, v. 10, n. 8, p. N.PAG, doi. 10.3390/biomedicines10081961

By:

Spannella, Francesco;
Giulietti, Federico;
Galeazzi, Roberta;
Passarelli, Anna;
Re, Serena;
Di Pentima, Chiara;
Allevi, Massimiliano;
Magni, Paolo;
Sarzani, Riccardo

Publication type:

Article

Determination of Serum Progranulin in Patients with Untreated Familial Hypercholesterolemia.

Published in:

Biomedicines, 2022, v. 10, n. 4, p. 771, doi. 10.3390/biomedicines10040771

By:

Nádró, Bíborka;
Lőrincz, Hajnalka;
Juhász, Lilla;
Szentpéteri, Anita;
Sztanek, Ferenc;
Varga, Éva;
Páll, Dénes;
Paragh, György;
Harangi, Mariann

Publication type:

Article

血清 PGRN、SFRP1、CCL26 与支气管哮喘急性发作期患者肺功能和气道炎症的相关性研究.

Published in:

Progress in Modern Biomedicine, 2023, v. 23, n. 15, p. 2873, doi. 10.13241/j.cnki.pmb.2023.15.014

By:

申燕华;
杭宇;
危蕾;
王众福;
李莉

Publication type:

Article

血清 APN、PGRN 联合检测对脓毒症患儿疾病的预测价值及与其预后的相关性分析.

Published in:

Progress in Modern Biomedicine, 2022, v. 22, n. 8, p. 1596, doi. 10.13241/j.cnki.pmb.2022.08.041

By:

霍风文;
张俊艳;
张德重;
金翠;
韩中斌

Publication type:

Article