Works about POLY(ADP-ribose) polymerase
Results: 1069
Olaparib increases chemosensitivity by upregulating miR-125a-3p in ovarian cancer cells.
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- Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02048-7
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- Article
Sublethal doses of copper sulphate initiate deregulation of glial cytoskeleton, NF-kB and PARP expression in Capoeta umbla brain tissue.
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- Regulatory Mechanisms in Biosystems, 2019, v. 10, n. 1, p. 103, doi. 10.15421/021916
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- Publication type:
- Article
Efficacy comparison of PD-1/PD-L1 inhibitor monotherapy and combination with PARPis or antiangiogenic agents in advanced or recurrent endometrial cancer: a systematic review and network meta-analysis.
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- BMC Women's Health, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12905-025-03612-7
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- Article
Capturing a Pentacyclic Fragment‐Based Library Derived from Perophoramidine: Their Design, Synthesis and Evaluation as Anticancer Compounds by DNA Double‐Strand Breaks (DSB) and PARP‐1 Inhibition.
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- Chemistry - A European Journal, 2022, v. 28, n. 63, p. 1, doi. 10.1002/chem.202202405
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- Article
Effects of small nucleolar RNA SNORD44 on the proliferation, apoptosis and invasion of glioma cells.
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- Histochemistry & Cell Biology, 2020, v. 153, n. 4, p. 257, doi. 10.1007/s00418-020-01848-y
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- Article
Evaluation of Cytotoxic Activity of New Benzimidazole-Piperazine Hybrids Against Human MCF-7 and A549 Cancer Cells.
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- Pharmaceutical Chemistry Journal, 2020, v. 53, n. 11, p. 1036, doi. 10.1007/s11094-020-02119-9
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- Article
Nanoparticles-SIRT1 Prevents Endothelial Progenitor Cells Senescence by Modulating Nitric Oxide Expression and Reducing Poly ADP-ribose Polymerase: In vitro Study.
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- Trends in Sciences, 2024, v. 21, n. 6, p. 1, doi. 10.48048/tis.2024.7519
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- Article
Design, synthesis, biological evaluation and molecular docking of novel molecules to PARP-1 enzyme.
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- Turkish Journal of Chemistry, 2019, v. 43, n. 5, p. 1290, doi. 10.3906/kim-1905-15
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- Publication type:
- Article
Revealing the selective mechanisms of inhibitors to PARP-1 and PARP-2 via multiple computational methods.
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- PeerJ, 2020, p. 1, doi. 10.7717/peerj.9241
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- Publication type:
- Article
Downfall of Iniparib: A PARP Inhibitor That Doesn't Inhibit PARP After All.
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- JNCI: Journal of the National Cancer Institute, 2014, v. 106, n. 1, p. 1, doi. 10.1093/jnci/djt447
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- Publication type:
- Article
Flavone-based dual PARP-Tubulin inhibitor manifesting efficacy against endometrial cancer.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2276665
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- Publication type:
- Article
Design and synthesis of benzodiazepines as brain penetrating PARP-1 inhibitors.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 952, doi. 10.1080/14756366.2022.2053524
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- Publication type:
- Article
1-Oxo-3,4-dihydroisoquinoline-4-carboxamides as novel druglike inhibitors of poly(ADP-ribose) polymerase (PARP) with favourable ADME characteristics.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1968, doi. 10.1080/14756366.2021.1972993
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- Publication type:
- Article
Three-component Castagnoli-Cushman reaction with ammonium acetate delivers 2-unsubstituted isoquinol-1-ones as potent inhibitors of poly(ADP-ribose) polymerase (PARP).
- Published in:
- Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1916, doi. 10.1080/14756366.2021.1969386
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- Publication type:
- Article
Identification of probe-quality degraders for Poly(ADP-ribose) polymerase-1 (PARP-1).
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 1606, doi. 10.1080/14756366.2020.1804382
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- Publication type:
- Article
Synthesis and biological evaluation of (3/4-(pyrimidin-2-ylamino)benzoyl)-based hydrazine-1-carboxamide/carbothioamide derivatives as novel RXRα antagonists.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 880, doi. 10.1080/14756366.2020.1740692
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- Publication type:
- Article
Ginsenoside Rd blocks AIF mitochondrio-nuclear translocation and NF-κB nuclear accumulation by inhibiting poly(ADP-ribose) polymerase-1 after focal cerebral ischemia in rats.
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- Neurological Sciences, 2013, v. 34, n. 12, p. 2101, doi. 10.1007/s10072-013-1344-6
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- Publication type:
- Article
Association of poly(ADP-ribose) polymerase-1 polymorphism with Tourette syndrome.
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- Neurological Sciences, 2013, v. 34, n. 11, p. 1911, doi. 10.1007/s10072-013-1405-x
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- Publication type:
- Article
BRD4 Inhibitor GNE-987 Exerts Anticancer Effects by Targeting Super-Enhancer-Related Gene LYL1 in Acute Myeloid Leukemia.
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- 2022
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- Publication type:
- journal article
Cases of consecutive ductal adenocarcinoma of the prostate carrying HRR mutation: case series and literature review.
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- Oxford Medical Case Reports, 2024, v. 2024, n. 10, p. 1, doi. 10.1093/omcr/omae124
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- Publication type:
- Article
Nicotinamide riboside supplementation does not alter whole‐body or skeletal muscle metabolic responses to a single bout of endurance exercise.
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- Journal of Physiology, 2021, v. 599, n. 5, p. 1513, doi. 10.1113/JP280825
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- Publication type:
- Article
A Novel Combination of Ruthenium Polypyridyl Complex, [Ru(dppz)2PiP]<sup>2+</sup> and PARP Inhibitor, NU1025 for Cancer Treatment.
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- Malaysian Journal of Medicine & Health Sciences, 2019, v. 15, p. 26
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- Publication type:
- Article
Myeloid malignancies in cancer patients treated with poly(ADP-ribose) polymerase (PARP) inhibitors: a case series.
- Published in:
- 2022
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- Publication type:
- Letter
PLK1 overexpression suppresses homologous recombination and confers cellular sensitivity to PARP inhibition.
- Published in:
- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-82724-w
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- Publication type:
- Article
PARP inhibition radiosensitizes BRCA1 wildtype and mutated breast cancer to proton therapy.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-81914-w
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- Publication type:
- Article
Cooperative dynamics of PARP-1 zinc-finger domains in the detection of DNA single-strand breaks.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-73707-y
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- Publication type:
- Article
Safety assessments and clinical features of PARP inhibitors from real-world data of Japanese patients with ovarian cancer.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-63600-z
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- Publication type:
- Article
5-Aminoisoquinolinone, a PARP-1 Inhibitor, Ameliorates Immune Abnormalities through Upregulation of Anti-Inflammatory and Downregulation of Inflammatory Parameters in T Cells of BTBR Mouse Model of Autism.
- Published in:
- Brain Sciences (2076-3425), 2021, v. 11, n. 2, p. 249, doi. 10.3390/brainsci11020249
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- Publication type:
- Article
Neuroprotective Effects of Activated Protein C Involve the PARP/AIF Pathway against Oxygen-Glucose Deprivation in SH-SY5Y Cells.
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- Brain Sciences (2076-3425), 2020, v. 10, n. 12, p. 959, doi. 10.3390/brainsci10120959
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- Publication type:
- Article
iNOS-Produced Nitric Oxide from Cancer Cells as an Intermediate of Stemness Regulation by PARP-1 in Colorectal Cancer.
- Published in:
- Biomolecules (2218-273X), 2025, v. 15, n. 1, p. 125, doi. 10.3390/biom15010125
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- Publication type:
- Article
Poly(ADP-Ribose) Polymerase (PARP) Inhibitors for Cancer Therapy: Advances, Challenges, and Future Directions.
- Published in:
- Biomolecules (2218-273X), 2024, v. 14, n. 10, p. 1269, doi. 10.3390/biom14101269
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- Publication type:
- Article
Radiosensitizing Effect of PARP Inhibition on Chondrosarcoma and Chondrocyte Cells Is Dependent on Radiation LET.
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- Biomolecules (2218-273X), 2024, v. 14, n. 9, p. 1071, doi. 10.3390/biom14091071
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- Publication type:
- Article
Combination Treatment Strategies to Overcome PARP Inhibitor Resistance.
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- Biomolecules (2218-273X), 2023, v. 13, n. 10, p. 1480, doi. 10.3390/biom13101480
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- Publication type:
- Article
The Role of Poly(ADP-ribose) Polymerase 1 in Nuclear and Mitochondrial Base Excision Repair.
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- Biomolecules (2218-273X), 2023, v. 13, n. 8, p. 1195, doi. 10.3390/biom13081195
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- Publication type:
- Article
Inherited Retinal Degeneration: Towards the Development of a Combination Therapy Targeting Histone Deacetylase, Poly (ADP-Ribose) Polymerase, and Calpain.
- Published in:
- Biomolecules (2218-273X), 2023, v. 13, n. 4, p. 581, doi. 10.3390/biom13040581
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- Publication type:
- Article
Metabolic Activation of PARP as a SARS-CoV-2 Therapeutic Target—Is It a Bait for the Virus or the Best Deal We Could Ever Make with the Virus? Is AMBICA the Potential Cure?
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- Biomolecules (2218-273X), 2023, v. 13, n. 2, p. 374, doi. 10.3390/biom13020374
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- Publication type:
- Article
Effects of the PARP Inhibitor Olaparib on the Response of Human Peripheral Blood Leukocytes to Bacterial Challenge or Oxidative Stress.
- Published in:
- Biomolecules (2218-273X), 2022, v. 12, n. 6, p. 788, doi. 10.3390/biom12060788
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- Publication type:
- Article
Inherited Retinal Degeneration: PARP-Dependent Activation of Calpain Requires CNG Channel Activity.
- Published in:
- Biomolecules (2218-273X), 2022, v. 12, n. 3, p. 455, doi. 10.3390/biom12030455
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- Publication type:
- Article
BRCAness as a Biomarker of Susceptibility to PARP Inhibitors in Glioblastoma Multiforme.
- Published in:
- Biomolecules (2218-273X), 2021, v. 11, n. 8, p. 1188, doi. 10.3390/biom11081188
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- Publication type:
- Article
Dual PARP and RAD51 Inhibitory Drug Conjugates Show Synergistic and Selective Effects on Breast Cancer Cells.
- Published in:
- Biomolecules (2218-273X), 2021, v. 11, n. 7, p. 981, doi. 10.3390/biom11070981
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- Publication type:
- Article
The Role of PARP Inhibitors in the Treatment of Prostate Cancer: Recent Advances in Clinical Trials.
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- Biomolecules (2218-273X), 2021, v. 11, n. 5, p. 722, doi. 10.3390/biom11050722
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- Publication type:
- Article
Anti-Survival and Pro-Apoptotic Effects of 6-Shogaol on SW872 Human Liposarcoma Cells via Control of the Intrinsic Caspase Pathway, STAT-3, AMPK, and ER Stress.
- Published in:
- Biomolecules (2218-273X), 2020, v. 10, n. 10, p. 1380, doi. 10.3390/biom10101380
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- Publication type:
- Article
PARP Inhibitors in Prostate and Urothelial Cancers.
- Published in:
- Frontiers in Oncology, 2020, p. 1, doi. 10.3389/fonc.2020.00114
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- Publication type:
- Article
PARP-1 negatively regulates nucleolar protein pool and mitochondrial activity: a cell protective mechanism.
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- Genes & Environment, 2024, v. 46, n. 1, p. 1, doi. 10.1186/s41021-024-00312-w
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- Publication type:
- Article
A Critical Appraisal and Recommendations for Cost-Effectiveness Studies of Poly(ADP-Ribose) Polymerase Inhibitors in Advanced Ovarian Cancer.
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- PharmacoEconomics, 2020, v. 38, n. 11, p. 1201, doi. 10.1007/s40273-020-00949-9
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- Publication type:
- Article
Proposal for Classifying the Emetogenicity of Oral Anticancer Agents with a Focus on PARP Inhibitors: A Prospective, Observational, Multicenter Study (JASCC-CINV 2002).
- Published in:
- Journal of Cancer, 2024, v. 15, n. 6, p. 1487, doi. 10.7150/jca.91675
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- Publication type:
- Article
Targeting NEAT1 Affects the Sensitivity to PARPi in Serous Ovarian Cancer by Regulating the Homologous Recombination Repair Pathway.
- Published in:
- Journal of Cancer, 2024, v. 15, n. 5, p. 1397, doi. 10.7150/jca.91896
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- Publication type:
- Article
Radiosensitization of Osteosarcoma Cells Using the PARP Inhibitor Olaparib Combined with X-rays or Carbon Ions.
- Published in:
- Journal of Cancer, 2024, v. 15, n. 3, p. 699, doi. 10.7150/jca.90371
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- Publication type:
- Article
The role of poly(ADP-ribose) polymerase inhibitors in the treatment of cancer and methods to overcome resistance: a review.
- Published in:
- Cell & Bioscience, 2020, v. 10, n. 1, p. 1, doi. 10.1186/s13578-020-00390-7
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- Publication type:
- Article
ATF3-induced activation of NF-κB pathway results in acquired PARP inhibitor resistance in pancreatic adenocarcinoma.
- Published in:
- Cellular Oncology (2211-3428), 2024, v. 47, n. 3, p. 939, doi. 10.1007/s13402-023-00907-5
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- Publication type:
- Article