Works about PHARMACOKINETICS

Results: 5000

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 3, p. 583, doi. 10.1002/psp4.13299
By:
- Said, Medhat M.;
- Schippers, Job R.;
- Atmowihardjo, Leila;
- Li, Yingxue;
- van der Plas, Mick S.;
- Bogaard, Harm J.;
- Bos, Lieuwe D. J.;
- Mathôt, Ron A. A.;
- Aman, Jurjan;
- Swart, Eleonora L.;
- Bartelink, Imke H.
Publication type:
Article
Population Pharmacokinetics and Transfer of Gabapentin When Used as a Pain Adjunct for Cesarean Deliveries.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 3, p. 551, doi. 10.1002/psp4.13295
By:
- Silvola, Rebecca;
- O'Kane, Aislinn;
- Heathman, Michael;
- Marotta, Hannah;
- Trussel, Hayley;
- Ray, Bobbie;
- Dowden, Shelley;
- Masters, Andrea R.;
- Haas, David M.;
- Quinney, Sara K.
Publication type:
Article
Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 3, p. 523, doi. 10.1002/psp4.13293
By:
- Ngo, Lien Thi;
- Jung, Woojin;
- Bui, Tham Thi;
- Yun, Hwi‐yeol;
- Chae, Jung‐woo;
- Momper, Jeremiah D.
Publication type:
Article
Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 3, p. 510, doi. 10.1002/psp4.13292
By:
- Chen, Shuqing;
- Shen, Chaozhuang;
- Tian, Yuchen;
- Peng, Yuhe;
- Hu, Jing;
- Xie, Haitang;
- Yin, Ping
Publication type:
Article
Mirikizumab pharmacokinetics and exposure–response in pediatric patients with moderate‐to‐severe ulcerative colitis.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 3, p. 474, doi. 10.1002/psp4.13286
By:
- Otani, Yuki;
- Chua, Laiyi;
- Komocsar, Wendy J.;
- Larkin, Amy;
- Johns, Jordan;
- Zhang, Xin
Publication type:
Article
A minimal physiologically‐based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti‐LAG‐3 monoclonal antibody.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 3, p. 460, doi. 10.1002/psp4.13285
By:
- Michelet, Robin;
- Petersson, Klas;
- Huisman, Marc C.;
- Menke‐van der Houven van Oordt, C. Willemien;
- Miedema, Iris H. C.;
- Thiele, Andrea;
- Montaseri, Ghazal;
- Pérez‐Pitarch, Alejandro;
- Busse, David
Publication type:
Article
Semi‐mechanistic population PK/PD model to aid clinical understanding of myelodysplastic syndromes following treatment with Venetoclax and Azacitidine.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 3, p. 448, doi. 10.1002/psp4.13284
By:
- Thakre, Neha;
- Maier, Corinna;
- Zha, Jiuhong;
- Engelhardt, Benjamin;
- Wolff, Johannes E.;
- Mensing, Sven
Publication type:
Article
Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 3, p. 435, doi. 10.1002/psp4.13186
By:
- Cai, Lianjin;
- Zhai, Jingchen;
- Ji, Beihong;
- Han, Fengyang;
- Niu, Taoyu;
- Wang, Luxuan;
- Wang, Junmei
Publication type:
Article
Pharmacokinetic variability and significance of therapeutic drug monitoring for broad-spectrum antimicrobials in critically ill patients.
Published in:
Journal of Pharmaceutical Health Care & Sciences, 2025, v. 11, n. 1, p. 1, doi. 10.1186/s40780-025-00425-6
By:
- Tanaka, Ryota
Publication type:
Article
Comparison of plasma concentration and sedative effect of sublingual and intranasal dexmedetomidine in children: A double‐blind randomised controlled study.
Published in:
Acta Anaesthesiologica Scandinavica, 2025, v. 69, n. 3, p. 1, doi. 10.1111/aas.14583
By:
- Khan, Armanullah;
- Sinha, Renu;
- Kumar, Kanil Ranjith;
- Velpandian, Trimurty;
- Maitra, Souvik;
- Ray, Bikash Ranjan
Publication type:
Article
The paradigm of stem cell secretome in tissue repair and regeneration: Present and future perspectives.
Published in:
Wound Repair & Regeneration, 2025, v. 33, n. 1, p. 1, doi. 10.1111/wrr.13251
By:
- Da Silva, Kate;
- Kumar, Pradeep;
- Choonara, Yahya E.
Publication type:
Article
Bioequivalence Study of Bedaquiline Fumarate Tablets in Healthy Chinese Subjects.
Published in:
Clinical Pharmacology in Drug Development, 2025, v. 14, n. 3, p. 263, doi. 10.1002/cpdd.1515
By:
- Yang, Man;
- Pei, Yingzi;
- Chen, Chen;
- Xi, Jian;
- Xia, Yue;
- Zhang, Shuyu;
- Liu, Huichen;
- Li, Aimin
Publication type:
Article
Equivalence of Biosimilarity in Pharmacokinetic and Pharmacodynamic Properties of Recombinant Human Insulin Aspart.
Published in:
Clinical Pharmacology in Drug Development, 2025, v. 14, n. 3, p. 209, doi. 10.1002/cpdd.1510
By:
- Dongre, Sneha A.;
- Kulkarni, Gauri A.;
- Thapa, Damodar;
- Ghade, Nikhil;
- Lona, Jeseena;
- Prajapati, Hiren;
- Mehta, Hiren;
- Guttikar, Swati;
- Krishnan, Archana R.;
- Sonar, Sanjay M.
Publication type:
Article
Bioavailability, Metabolism, and Excretion of [<sup>14</sup>C]‐Tazemetostat in Patients With B‐Cell Lymphomas or Advanced Solid Tumors.
Published in:
Clinical Pharmacology in Drug Development, 2025, v. 14, n. 3, p. 231, doi. 10.1002/cpdd.1508
By:
- Chen, Yingxue;
- Teng, Renli;
- Ogier, Julien
Publication type:
Article
Pharmacokinetics of Depemokimab Delivered by Safety Syringe Device or Autoinjector in Healthy Adults: A Phase 1, Single‐Dose Study.
Published in:
Clinical Pharmacology in Drug Development, 2025, v. 14, n. 3, p. 190, doi. 10.1002/cpdd.1506
By:
- Schalkwijk, Stein;
- Zecchin, Chiara;
- Sen, Anusmita;
- Choi, Sei;
- Wang, Kai;
- Min, Jeff;
- Spears, Brian
Publication type:
Article
Bioequivalence Study of 2 Formulations of Fluticasone Nasal Spray in Healthy Chinese Volunteers.
Published in:
Clinical Pharmacology in Drug Development, 2025, v. 14, n. 3, p. 270, doi. 10.1002/cpdd.1505
By:
- Chen, Gang;
- Wang, Zejuan;
- Liu, Xiaona;
- Du, Aihua;
- Li, Min;
- Zhang, Yanan;
- Zhang, Dan;
- Wang, Xiaolin;
- Li, Xueyan;
- Cong, Wei;
- Wang, Jin
Publication type:
Article
Phase 1 Mass Balance Study of Pizuglanstat: An Investigational Hematopoietic Prostaglandin D Synthase Inhibitor.
Published in:
Clinical Pharmacology in Drug Development, 2025, v. 14, n. 3, p. 200, doi. 10.1002/cpdd.1504
By:
- Hanada, Ryuzo;
- Takenaka, Toru
Publication type:
Article
Population Pharmacokinetic Modeling of Certepetide in Human Subjects With Metastatic Pancreatic Ductal Adenocarcinoma.
Published in:
Clinical Pharmacology in Drug Development, 2025, v. 14, n. 3, p. 240, doi. 10.1002/cpdd.1502
By:
- Winning, Alex;
- Sietsema, William K.;
- Buck, Kristen K.;
- Linsmeier, Abigail;
- Wiczling, Pawel
Publication type:
Article
A Drug–Drug Interaction Study of Mobocertinib and Midazolam, a Cytochrome P450 3A Substrate, in Patients With Advanced Non–Small Cell Lung Cancer.
Published in:
Clinical Pharmacology in Drug Development, 2025, v. 14, n. 3, p. 252, doi. 10.1002/cpdd.1500
By:
- Hanley, Michael J.;
- Zhang, Steven;
- Pavlakis, Nick;
- Soo, Ross A.;
- van der Wekken, Anthonie J.;
- Ganju, Vinod;
- Piña, Adela;
- Dong, Qi;
- Gupta, Neeraj
Publication type:
Article
Determination of the Bioavailability of 3 Intranasal Formulations of Azelastine Hydrochloride in Healthy Male Volunteers.
Published in:
Clinical Pharmacology in Drug Development, 2025, v. 14, n. 3, p. 217, doi. 10.1002/cpdd.1498
By:
- Bousquet, Jean;
- Klimek, Ludger;
- Liu, Mark;
- Nguyen, Duc Tung;
- Ramalingam, Rajesh Kumar;
- Canonica, Georgio Walter;
- Berger, William E.
Publication type:
Article
Parameter combination norfloxacin and tylosin on poultry: A review.
Published in:
Journal of Tropical Animal & Veterinary Sciences / Jurnal Ilmu Peternakan dan Veteriner Tropis, 2025, v. 15, n. 1, p. 1, doi. 10.46549/jipvet.v15i1.489
By:
- Wibisono, Cahyo;
- Pamudya, Kanya Gabriella Sasri;
- Dwi Wijayanti, Agustina;
- Widiasih, Dyah Ayu;
- Tjahajati, Ida;
- Indarjulianto, Soedarmanto
Publication type:
Article
Discovering the Potential Mechanisms of Canna indica Leaves Ethanolic Extract against Plasmodium falciparum Malaria: Network Pharmacology and Molecular Docking Approach.
Published in:
Tropical Journal of Natural Product Research, 2025, v. 9, n. 2, p. 702, doi. 10.26538/tjnpr/v9i2.37
By:
- Mardhiyyah, Kana;
- Johan, Christopher K.;
- Ravsanjani, Eurica A. N.
Publication type:
Article
A phase 1 dose‐escalation study of LY3295668 erbumine as monotherapy and in combination with topotecan and cyclophosphamide in children with relapsed/refractory neuroblastoma.
Published in:
Cancer (0008543X), 2025, v. 131, n. 4, p. 1, doi. 10.1002/cncr.35751
By:
- DuBois, Steven G.;
- Ogawa, Chitose;
- Moreno, Lucas;
- Mossé, Yaël P.;
- Fischer, Matthias;
- Ryan, Anne L.;
- Vo, Kieuhoa T.;
- De Wilde, Bram;
- Rubio‐San‐Simon, Alba;
- Macy, Margaret E.;
- Howell, Lisa;
- Shusterman, Suzanne;
- Corradini, Nadège;
- Luksch, Roberto;
- Aerts, Isabelle;
- Foster, Jennifer H.;
- Weiss, Brian D.;
- Karthik, Chandrasekhar Pamidipati;
- Yuen, Eunice;
- Avsar, Emin
Publication type:
Article
Characterization of the nicotine uptake and safety of Nordic spirit tobacco-free oral nicotine pouches: A randomized cross-over study.
Published in:
Psychopharmacology, 2025, v. 242, n. 4, p. 855, doi. 10.1007/s00213-024-06721-7
By:
- Renard, Karine;
- Nishihara, Daisuke;
- Nilsson, Johan;
- Larroque, Sylvain;
- Martinez, Javier;
- Giles, Lesley
Publication type:
Article
Inorganic mercury pharmacokinetics in man: a hybrid model.
Published in:
Xenobiotica, 2025, v. 55, n. 1, p. 4, doi. 10.1080/00498254.2024.2448979
By:
- Farris, Fred;
- Awaness, Ayda;
- Su, Joe
Publication type:
Article
QbD Based Development, Characterization and Pharmacokinetic Evaluation of Enzalutamide-Loaded Cyclodextrin Nano Sponges for Enhanced Drug Delivery.
Published in:
Indian Journal of Pharmaceutical Education & Research, 2025, v. 59, p. 89, doi. 10.5530/ijper.20255427
By:
- Medarametla, Ramya Teja;
- Radha, Gadela Venkata
Publication type:
Article
Pharmacokinetics and bioequivalence of two formulations of the S-1 (tegafur/gimeracil/oxonate) capsule in Chinese cancer patients under fasting and fed conditions: a multicenter, randomized, open-label, single-dose, double-cycle crossover study.
Published in:
Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1494902
By:
- Lu, Junli;
- Lei, Yuyan;
- Mo, Yuanyuan;
- Wang, Xiangping;
- Liu, Wanying;
- Yan, Yu;
- Yang, Hongying;
- Li, Canxia;
- Huang, Lifeng;
- Shen, Qiuxia;
- Wang, Caihong;
- Chen, Jingjie;
- Chen, Lulu;
- Li, Xiaohui
Publication type:
Article
Prucalopride Still Effective in CIC Despite Older Age, Unhealthy BMI or Renal Impairment.
Published in:
Healio Gastroenterology, 2025, v. 11, n. 2, p. 37
By:
- Stonehill, Monica
Publication type:
Article
Optimization of the poloxamer 407-conjugated gelatin to synthesize pH-sensitive nanocarriers for controlled paclitaxel delivery.
Published in:
Journal of Polymer Research, 2025, v. 32, n. 2, p. 1, doi. 10.1007/s10965-024-04248-1
By:
- Ly, Huy Q.;
- Chen, Yin-Ju;
- Nguyen, Van Toan;
- Tseng, Ching-Li
Publication type:
Article
ADVANCEMENTS IN PREDICTING ADVERSE DRUG REACTIONS USING PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELS: A COMPREHENSIVE REVIEW.
Published in:
Acta Poloniae Pharmaceutica, 2024, v. 81, n. 5, p. 879, doi. 10.32383/appdr/196928
By:
- HUI LIU;
- ZHUOMIN LI;
- QING SHAO;
- YANLI NING;
- QINGJUN GUO
Publication type:
Article
Population pharmacokinetic modeling of asciminib in support of exposure-response and ethnic sensitivity analyses in patients with chronic myeloid leukemia.
Published in:
Cancer Chemotherapy & Pharmacology, 2025, v. 95, n. 1, p. 1, doi. 10.1007/s00280-025-04755-y
By:
- Darstein, Christelle;
- Yoon, Deokyong;
- Yang, Yiqun;
- Kapoor, Shruti;
- Dasgupta, Kohinoor;
- Wu, Shengyuan;
- Kawakita, Yasunori;
- Hoch, Matthias;
- Grosch, Kai;
- Sy, Sherwin K. B.
Publication type:
Article
Corrigendum: Population pharmacokinetics and dosing optimization of imipenem in Chinese elderly patients.
Published in:
2025
By:
- Wang, Jing;
- Fang, Qiu;
- Luo, Xuemei;
- Jin, Lu;
- Zhu, Huaijun
Publication type:
Correction Notice
Population pharmacokinetics and dosing optimization of imipenem in Chinese elderly patients.
Published in:
Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2024.1524272
By:
- Wang, Jing;
- Fang, Qiu;
- Luo, Xuemei;
- Jin, Lu;
- Zhu, Huaijun
Publication type:
Article
A Review Study on Reverse Iontophoresis and Its Applications.
Published in:
Pharmaceutical & Biomedical Research, 2024, v. 10, n. 4, p. 279, doi. 10.32598/PBR.10.4.1324.1
By:
- Sami, Hesham;
- Jain, Ashish;
- Singhai, Akhlesh Kumar
Publication type:
Article
Pharmacokinetics of Non-Psychotropic Phytocannabinoids.
Published in:
Pharmaceutics, 2025, v. 17, n. 2, p. 236, doi. 10.3390/pharmaceutics17020236
By:
- Lacerda, Mariana;
- Carona, Andreia;
- Castanheira, Sara;
- Falcão, Amílcar;
- Bicker, Joana;
- Fortuna, Ana
Publication type:
Article
Integrating In Vitro Dissolution and Physiologically Based Pharmacokinetic Modeling for Generic Drug Development: Evaluation of Amorphous Solid Dispersion Formulations for Tacrolimus.
Published in:
Pharmaceutics, 2025, v. 17, n. 2, p. 227, doi. 10.3390/pharmaceutics17020227
By:
- Karakitsios, Evangelos;
- Angelerou, Maria-Faidra-Galini;
- Kapralos, Iasonas;
- Tsakiridou, Georgia;
- Kalantzi, Lida;
- Dokoumetzidis, Aristides
Publication type:
Article
Prediction of Pharmacokinetics for CYP3A4-Metabolized Drugs in Pediatrics and Geriatrics Using Dynamic Age-Dependent Physiologically Based Pharmacokinetic Models.
Published in:
Pharmaceutics, 2025, v. 17, n. 2, p. 214, doi. 10.3390/pharmaceutics17020214
By:
- Han, Jing;
- Zhang, Zexin;
- Liu, Xiaodong;
- Yang, Hanyu;
- Liu, Li
Publication type:
Article
Computational Evaluation of Improved HIPEC Drug Delivery Kinetics via Bevacizumab-Induced Vascular Normalization.
Published in:
Pharmaceutics, 2025, v. 17, n. 2, p. 155, doi. 10.3390/pharmaceutics17020155
By:
- Namakshenas, Pouya;
- Crezee, Johannes;
- Tuynman, Jurriaan B.;
- Tanis, Pieter J.;
- Oei, Arlene L.;
- Kok, H. Petra
Publication type:
Article
Current Trends in Clinical Trials of Prodrugs.
Published in:
Pharmaceuticals (14248247), 2025, v. 18, n. 2, p. 210, doi. 10.3390/ph18020210
By:
- Boreski, Diogo;
- Schmid, Valentine Fabienne;
- Bosquesi, Priscila Longhin;
- dos Santos, Jean Leandro;
- Scarim, Cauê Benito;
- Reshetnikov, Viktor;
- Chin, Chung Man
Publication type:
Article
Synergistic Interaction Between Justicia spicigera Extract and Analgesics on the Formalin Test in Rats.
Published in:
Pharmaceuticals (14248247), 2025, v. 18, n. 2, p. 187, doi. 10.3390/ph18020187
By:
- Zapata-Morales, Juan Ramón;
- Alonso-Castro, Angel Josabad;
- González-Rivera, María Leonor;
- González Prado, Hugo Israel;
- Barragán-Gálvez, Juan Carlos;
- Hernández-Flores, Araceli;
- Juárez-Vázquez, María del Carmen;
- Domínguez, Fabiola;
- Carranza-Álvarez, Candy;
- de Jesús Pozos-Guillén, Amaury;
- López-Rodríguez, Juan F.;
- Aguirre-Bañuelos, Patricia;
- Ramírez-Morales, Marco Antonio
Publication type:
Article
Impact of Genetic Variants on Pregabalin Pharmacokinetics and Safety.
Published in:
Pharmaceuticals (14248247), 2025, v. 18, n. 2, p. 151, doi. 10.3390/ph18020151
By:
- Calleja, Sofía;
- Rodríguez-López, Andrea;
- Ochoa, Dolores;
- Luquero, Sergio;
- Navares-Gómez, Marcos;
- Román, Manuel;
- Mejia-Abril, Gina;
- Martín-Vilchez, Samuel;
- Abad-Santos, Francisco;
- Zubiaur, Pablo
Publication type:
Article
Encapsulation of anti-VEGF nanobody into niosome nanoparticles: a novel approach to enhance circulation half life and efficacy.
Published in:
Journal of Microencapsulation, 2025, v. 42, n. 2, p. 132, doi. 10.1080/02652048.2024.2443435
By:
- Chiani, Mohsen;
- Abedini, Raha;
- Ahangari-Cohan, Reza;
- Behdani, Mahdi;
- Barzi, Seyed Mahmoud;
- Mohseni, Nastaran;
- Kazemi-Lomedasht, Fatemeh
Publication type:
Article
Evaluating the Real-World Pharmacokinetics of Risperidone ISM ® in Routine Clinical Practice.
Published in:
Biomedicines, 2025, v. 13, n. 2, p. 384, doi. 10.3390/biomedicines13020384
By:
- Toja-Camba, Francisco José;
- Vidal-Millares, María;
- Duran-Maseda, María José;
- Arrojo-Romero, Manuel;
- Puente-Iglesias, María;
- Hermelo-Vidal, Gonzalo;
- Feitosa-Medeiros, Carolina;
- Fernández-Ferreiro, Anxo;
- Mondelo-García, Cristina
Publication type:
Article
Advances in Pharmacological Research on Icaritin: A Comprehensive Review.
Published in:
American Journal of Chinese Medicine, 2025, v. 53, n. 1, p. 179, doi. 10.1142/S0192415X25500089
By:
- Guo, Ran;
- Yan, Zhiping;
- Wang, Rui;
- Guo, Tongxuan;
- Li, Hao;
- Kong, Minyu;
- Guo, Wenzhi
Publication type:
Article
A phase 1 study of the combination of BH3-mimetic, navitoclax, and mTORC1/2 inhibitor, vistusertib, in patients with advanced solid tumors.
Published in:
Cancer Chemotherapy & Pharmacology, 2025, v. 95, n. 1, p. 1, doi. 10.1007/s00280-025-04760-1
By:
- Scott, Susan C.;
- Farago, Anna;
- Lai, W. Victoria;
- Zahurak, Marianna;
- Rudek, Michelle A.;
- Murray, Judy;
- Carducci, Michael A.;
- Uziel, Tamar;
- Takebe, Naoko;
- Gore, Steven D.;
- Rudin, Charles M.;
- Hann, Christine L.
Publication type:
Article
Clinical safety and pharmacokinetics of a novel oral niclosamide formulation compared with marketed niclosamide chewing tablets in healthy volunteers: A three-part randomized, double-blind, placebo-controlled trial.
Published in:
PLoS ONE, 2025, v. 20, n. 2, p. 1, doi. 10.1371/journal.pone.0303924
By:
- Walther, Niklas;
- Schultz-Heienbrok, Robert;
- Staß, Heino;
- Corman, Victor M.;
- Gassen, Nils C.;
- Müller, Marcel A.;
- Drosten, Christian;
- Witzenrath, Martin;
- Lee, Hweeling;
- Posch, Maximilian G.
Publication type:
Article
Dimension in a Quarter: Part 1 Pharmacotherapy.
Published in:
Diabetic Foot Journal, 2013, v. 16, n. 1, p. 29
By:
- Young, Matthew
Publication type:
Article
Polypharmacy in older people: The need for deprescribing.
Published in:
Practice Nursing, 2018, v. 29, n. 8, p. 390, doi. 10.12968/pnur.2018.29.8.390
By:
- Kaufman, Gerri
Publication type:
Article
Costs and benefits of generic prescribing after a kidney transplant.
Published in:
Practice Nursing, 2011, v. 22, n. 11, p. 570, doi. 10.12968/pnur.2011.22.11.570
By:
- Gupta, Gaurav;
- Batra, Ramesh;
- Alachkar, Nada
Publication type:
Article
Understanding inhaler devices, 1: Principles.
Published in:
Practice Nursing, 2009, v. 20, n. 11, p. 556, doi. 10.12968/pnur.2009.20.11.45075
By:
- Booker, Rachel
Publication type:
Article