Works matching DE "PHARMACODYNAMICS"

Results: 5000

In vitro phytochemical, antioxidant activity and antimycobacterial potentials of selected medicinal plants commonly used for respiratory infections and related symptoms in the Limpopo Province, South Africa.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-05002-w

By:

Matlala, Maphuti S.;
Moganedi, Kgabo L. M.;
Masoko, Peter

Publication type:

Article

Topical Mupirocin Treatment Reduces Interferon and Myeloid Signatures in Cutaneous Lupus Erythematous Lesions Through Targeting of Staphylococcus Species.

Published in:

Arthritis & Rheumatology, 2025, v. 77, n. 6, p. 705, doi. 10.1002/art.43079

By:

Abernathy‐Close, Lisa;
Mears, Joseph;
Billi, Allison C.;
Sirobhushanam, Sirisha;
Berthier, Celine;
Lu, Annie;
Zhang, Zeran;
Hurst, Amy;
Gudjonsson, Johann E.;
Kahlenberg, J. Michelle

Publication type:

Article

JAK Inhibitors and Inflammatory Nail Disorders: A Systematic Review of Clinical Outcomes and Therapeutic Potential.

Published in:

American Journal of Clinical Dermatology, 2025, v. 26, n. 4, p. 525, doi. 10.1007/s40257-025-00946-8

By:

Iorizzo, Matilde;
Sechi, Andrea;
Neubauer, Zachary J. K.;
Zhou, Maggie;
Lipner, Shari R.

Publication type:

Article

Buprenorphine Extended-Release Injection for Subcutaneous Use (Sublocade<sup>®</sup>): An Overview for Psychiatric Advanced Practice Nurses.

Published in:

Journal of Psychosocial Nursing & Mental Health Services, 2025, v. 63, n. 7, p. 7, doi. 10.3928/02793695-20250612-03

By:

Kameg, Brayden

Publication type:

Article

CRISPRi knockdown of mycobacterial tkt gene potentiates the anti-mycobacterial activity of phyto-compounds from selected medicinal plants.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04987-8

By:

Matotoka, Mashilo Mash;
Mashabela, Gabriel Tshwahla;
Masoko, Peter

Publication type:

Article

Evaluation of the in vivo antidiabetic, in vitro antioxidant and alpha amylase inhibitory effects of Ocimum lamiifolium Hochst ex Benth leaf hydromethanolic crude extract in streptozotocin-induced diabetic mouse model.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04986-9

By:

Mengistu, Gedefaw Getie;
Getahun, Kefyalew Ayalew;
Tiruneh, Markeshaw;
Tezera, Hiwot;
Molla, Meseret Derbew

Publication type:

Article

Investigation of the potential anxiolytic effects of essential oils derived from two sacred plants of tantric buddhism: Rhododendron anthopogon d.don and Juniperus indica Bertol.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04954-3

By:

Cornara, Laura;
Valussi, Marco;
Gurung, Khilendra;
Lama, Lapka Sherpa;
Polito, Flavio;
De Feo, Vincenzo

Publication type:

Article

In vitro study of anti-sickling effects of aqueous extracts of Garcinia kola (seeds), Zingiber officinale (rhizomes) and Allium sativum(bulbs) on sodium metabisulphite-treated HBSS erythrocytes.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04943-6

By:

Salawu, M. O.;
Abdulsalam, I. O.;
Oloyede, H. O. B.

Publication type:

Article

Alterations of bone proteins in medication‐related osteonecrosis of the jaw.

Published in:

European Journal of Oral Sciences, 2025, v. 133, n. 2, p. 1, doi. 10.1111/eos.70003

By:

Schubert, Andrea;
Brockmeyer, Phillipp;
Kauffmann, Philipp;
Wiegel, Jan;
Lautenbacher, Florian;
Miosge, Nicolai;
Schminke, Boris

Publication type:

Article

Effectiveness and safety of direct oral anticoagulants combined with antiplatelet agents in patients with acute coronary syndrome following percutaneous coronary intervention, with or without atrial fibrillation: A systematic review and network meta-analysis

Published in:

Polish Heart Journal / Kardiologia Polska, 2025, v. 83, n. 6, p. 678, doi. 10.33963/v.phj.105956

By:

Yirou Cai;
Changlin Zhai;
Liang Shen;
Shiyong Xu

Publication type:

Article

Safety, pharmacokinetics and pharmacodynamics of Efsubaglutide Alfa in healthy participants: A randomised, dose‐escalation phase 1 study.

Published in:

Diabetes, Obesity & Metabolism, 2025, v. 27, n. 8, p. 4220, doi. 10.1111/dom.16452

By:

Wang, Qinghua;
Cui, Qiaoli;
Xu, Yulong;
Prud'homme, Gerald J.;
Yang, Yuanxun;
Zhu, Dalong;
Li, Yiming;
Yang, Yehong;
Li, Juan

Publication type:

Article

Treatment of rheumatoid arthritis by Rhododendron molle G. Don: the anti-inflammatory mechanism of its extract was elucidated by network analysis combined with experimental verification.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04982-z

By:

Mei, Wenya;
Yu, Junbao;
Zhu, Jiayuan;
Deng, Ting;
Deng, Yasi;
Tong, Qiaozhen;
Liu, Xiangdan;
Yu, Huanghe;
Zhou, Ribao;
Liu, Xiaorong

Publication type:

Article

Bioprospection of indigenous herbal formulations for diabetes care: in vitro, network pharmacology, and molecular dynamics studies.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04980-1

By:

Ojo, Oluwafemi Adeleke;
Ogunlakin, Akingbolabo Daniel;
Ajayi-Odoko, Omolola Adenike;
Gyebi, Gideon Ampoma;
Ayokunle, Damilare IyinKristi;
Olanrewaju, Adesoji Alani;
Agbeye, Oluwatobi Deborah;
Ogunwale, Emmanuel Tope;
Adeyemi, Oluyomi Stephen

Publication type:

Article

Profiling metoprolol enantiomers in urine of hypertensive patients.

Published in:

DARU: Journal of Pharmaceutical Sciences, 2025, v. 33, n. 2, p. 1, doi. 10.1007/s40199-025-00563-0

By:

Seyfinejad, Behrouz;
Jouyban, Kimiya;
Houshyar, Jalil;
Jabbaripour Sarmadian, Amirreza;
Jouyban, Abolghasem

Publication type:

Article

Antiproliferative activities of phytochemicals isolated from the leaves of Dolichos kilimandischaricus (Harms) ex Taub. (Fabaceae) on Jurkat and HL-60 leukemic cells.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04977-w

By:

Sithole, Simbarashe;
Mushonga, Paul;
Heydenreich, Matthias;
Mawere, Cephas;
Mukanganyama, Stanley

Publication type:

Article

PLGA-based herb Toosendanin delivery system for efficient therapy of oral squamous cell carcinoma.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04957-0

By:

Chen, Lingling;
Feng, Cheng;
Shi, Zhenyu;
Wang, Jianzhe;
Wang, Tao;
Wang, Yibing;
Lin, Lisong;
Wu, Ye

Publication type:

Article

The anticancer potential of Origanum onites L. in gastric cancer through epigenetic alterations.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04942-7

By:

Sogutlu, Fatma;
Pekerbas, Mert;
Boztas, Gulsum;
Bayram, Emine;
Pariltay, Erhan;
Cogulu, Ozgur;
Biray Avci, Cigir

Publication type:

Article

Harnessing animal model and computational experiments to discover antidiabetic compounds in Ficus racemosa.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04845-7

By:

Hossain, Mohammad Uzzal;
Rahman, A. B. Z. Naimur;
Hossain, Md. Shahadat;
Dey, Shajib;
Chowdhury, Zeshan Mahmud;
Bhattacharjee, Arittra;
Ahammad, Ishtiaque;
Hasan, Mohammad Kamrul;
Ahmed, Istiak;
Hosen, Md. Billal;
Das, Keshob Chandra;
Keya, Chaman Ara;
Salimullah, Md.

Publication type:

Article

Anticancer and cancer preventive activities of shogaol and curcumin from Zingiberaceae family plants in KG-1a leukemic stem cells.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04829-7

By:

Panyajai, Pawaret;
Viriyaadhammaa, Natsima;
Chiampanichayakul, Sawitree;
Sakamoto, Yasuhisa;
Okonogi, Siriporn;
Moroishi, Toshiro;
Anuchapreeda, Songyot

Publication type:

Article

Integrating network pharmacology and multi-omics in a systems approach: a mechanism study of Jinhong tablets against chronic superficial gastritis.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01138-6

By:

Xiao, Lihao;
Zhang, Tingyu;
Liu, Yun;
Sutcharitchan, Chayanis;
Liu, Qingyuan;
Fan, Xiaoxue;
Feng, Jian;
Gao, Huifang;
Li, Shao;
Zhang, Tong

Publication type:

Article

Decoding the anti-thrombotic effects of leonurine: a multimodal approach combining TCM repositioning and mTOR signaling.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01160-8

By:

Dong, Xin;
Jia, Shuaibing;
Zhang, Leifeng;
Liang, Yong;
Zhang, Jianhua;
Zhu, Yi Zhun

Publication type:

Article

A computational-based new treatment strategy with three-armed RCT on Mycoplasma pneumoniae pneumonia in children.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01149-3

By:

Zhong, Chengliang;
Liu, Qingyuan;
Guo, Shengxuan;
Sun, Deyang;
Wang, Boyang;
Hu, Siyuan;
Li, Xinmin;
Zhao, Weibo;
Ding, Ying;
Yuan, Bin;
Liu, Jing;
Xiang, Long;
Li, Nan;
Xue, Zheng;
Li, Yan;
Teng, Yiqun;
Yi, Rongsong;
Li, Shao;
Ma, Rong

Publication type:

Article

Phytochemical analysis and in vitro biological activity assessment of extracts from Micromeria myrtifolia.

Published in:

International Journal of Environmental Health Research, 2025, v. 35, n. 7, p. 1833, doi. 10.1080/09603123.2024.2409829

By:

T, Taskın;
M, Oksuz;
E, Rayaman;
M, Ermanoglu;
D, Taskın;
A.G, Acar;
Ö, Kılıç;
E, Çalışkan Salihi;
B, Yılmaz Nur;
Hk, Elçioğlu

Publication type:

Article

Antioxidants from Rubus idaeus leaves: LC-MS/MS chemical profiling, in vitro antiglycation, α-glucosidase and α-amylase inhibitory activities.

Published in:

International Journal of Environmental Health Research, 2025, v. 35, n. 7, p. 1739, doi. 10.1080/09603123.2024.2404248

By:

Sara, El Asri;
Reda, Ben Mrid;
Zakia, Zouaoui;
Bitwell, Chibuye;
Abdelhamid, Ennoury;
Imad, Kabach;
Mohamed, Nhiri;
Fatiha, Chibi

Publication type:

Article

Drug Repurposing for Targeting ISL LIM Homeobox 2 in Treatment of Endometriosis: A Computational Study.

Published in:

International Journal of Fertility & Sterility, 2025, v. 19, n. 3, p. 277, doi. 10.22074/ijfs.2025.2009299.1516

By:

Mahdian, Soodeh;
Favaedi, Raha;
Mikaeeli, Gelareh;
Moini, Ashraf;
Shahhoseini, Maryam

Publication type:

Article

Multi‐ancestry genome‐wide association study of topiramate's effects on heavy alcohol use.

Published in:

Alcohol, Clinical & Experimental Research, 2025, v. 49, n. 6, p. 1197, doi. 10.1111/acer.70069

By:

Davis, Christal N.;
Jinwala, Zeal;
Justice, Amy C.;
Rentsch, Christopher T.;
Kranzler, Henry R.

Publication type:

Article

Examining the predictive validity of alcohol‐seeking following punishment‐imposed abstinence in mice.

Published in:

Alcohol, Clinical & Experimental Research, 2025, v. 49, n. 6, p. 1337, doi. 10.1111/acer.70057

By:

Tran, Linh;
Kuznetsova, Maria;
Manning, Elizabeth E.;
Campbell, Erin J.

Publication type:

Article

Moderation of treatment outcomes by polygenic risk for alcohol‐related traits in placebo‐controlled trials of topiramate.

Published in:

Alcohol, Clinical & Experimental Research, 2025, v. 49, n. 6, p. 1297, doi. 10.1111/acer.70052

By:

Kranzler, Henry R.;
Jinwala, Zeal;
Davis, Christal N.;
Xu, Heng;
Biernacka, Joanna M.;
Zhou, Hang;
Kember, Rachel L.;
Gelernter, Joel;
Feinn, Richard

Publication type:

Article

The impact of pharmacological agents on neuroinflammation in neurodegenerative diseases.

Published in:

Acta Marisiensis. Seria Medica, 2025, v. 71, n. 2, p. 95, doi. 10.2478/amma-2025-0018

By:

Sharma, Anurag;
Khan, Zoya;
Nath, Rajendra;
Dixit, Rakesh Kumar

Publication type:

Article

Sesquiterpenes with anti-inflammatory activity from the stems and branches of Melicope patulinervia.

Published in:

Journal of Asian Natural Products Research, 2025, v. 27, n. 7, p. 977, doi. 10.1080/10286020.2025.2508874

By:

Li, Sai;
Du, En-Lian;
Gong, Qi;
Chen, Fei;
Tan, Jun-Jie;
Qu, Shi-Jin;
Zhang, Hai-Yan;
Tan, Chang-Heng

Publication type:

Article

Resveratrol: a potential alternative therapeutic agent for patients suffering from chronic obstructive pulmonary disease (COPD).

Published in:

Journal of Asian Natural Products Research, 2025, v. 27, n. 7, p. 951, doi. 10.1080/10286020.2025.2459597

By:

Ren, Ong Yan;
Siddiqui, Yasmeen;
Ansari, Mohammed Tahir;
Ali, Asgar

Publication type:

Article

Exploration and computational assessment of ochrocephalamine G from Oxytropis ochrocephala as an anti-HBV candidate.

Published in:

Journal of Asian Natural Products Research, 2025, v. 27, n. 7, p. 1058, doi. 10.1080/10286020.2024.2441773

By:

Zhang, Ya-Kun;
Xue, Zhan;
Tong, Jian-Bo;
Tan, Jing;
Yang, Min;
Zeng, Yan-Rong;
Tan, Cheng-Jian

Publication type:

Article

Isotretinoin and Thyroid Dysfunction: A Call for Routine Monitoring.

Published in:

Dermatologic Therapy, 2025, v. 2025, p. 1, doi. 10.1155/dth/4503927

By:

Iftikhar, Zoha;
Ghanem, Laura;
Sheraz, Maheen;
Ahmed, Mansoor;
Rath, Shree;
Husain, Mustafa;
Suraiya, Saleem

Publication type:

Article

Liver function effects of SGLT2 inhibitor and GLP‐1 receptor agonist combination treatment in patients with type 2 diabetes (post hoc analysis of RECAP study).

Published in:

Journal of Diabetes Investigation, 2025, v. 16, n. 7, p. 1243, doi. 10.1111/jdi.70066

By:

Tsuriya, Daisuke;
Kobayashi, Kazuo;
Takeshita, Kei;
Hashimoto, Takuya;
Kimura, Moritsugu;
Muta, Yoshimi;
Yokomizo, Hisashi;
Takashi, Yuichi;
Tsukamoto, Shunichiro;
Tamura, Kouichi;
Kanasaki, Keizo;
Kawanami, Daiji;
Toyoda, Masao

Publication type:

Article

Induction of proximal tubular proliferation and lengthening in response to sodium glucose linked cotransporter‐2 inhibition in experimental rats.

Published in:

Journal of Diabetes Investigation, 2025, v. 16, n. 7, p. 1232, doi. 10.1111/jdi.70043

By:

Wu, Ellen;
Macklin, Sarah;
Zhang, Yanling;
Thai, Kerri;
Nghiem, Linda;
Di Ciano‐Oliveira, Caterina;
Coelho, Nuno;
Wang, Hai;
Advani, Suzanne L.;
Desjardins, Jean‐François;
Yuen, Darren A;
Misra, Paraish;
Connelly, Kim A.;
Nyengaard, Jens R.;
Gilbert, Richard E.

Publication type:

Article

Effects of sodium-glucose cotransport-2 inhibitors treatment in patients with pulmonary hypertension.

Published in:

Therapeutic Advances in Respiratory Disease, 2025, p. 1, doi. 10.1177/17534666251351443

By:

Obeidat, Mohammed;
Vignarajah, Aravinthan;
Abdel-Razeq, Rashid;
Nathir, Ala'eddien;
Vigneswaramoorthy, Nishanthi A.;
Tonelli, Adriano R.

Publication type:

Article

Rituximab to Prevent Relapse in Anti-NMDAR Antibody-Mediated Encephalitis.

Published in:: Neurology Alert, 2025, v. 44, n. 11, p. 1
Publication type:: Article

Prognostic Factors Influencing the Efficacy of Regorafenib in the Treatment of Metastatic Colorectal Cancer.

Published in:

Namık Kemal Tıp Dergisi, 2025, v. 13, n. 2, p. 1, doi. 10.4274/nkmj.galenos.2025.34654

By:

SEVER, Nadiye;
BAYOĞLU, İbrahim Vedat

Publication type:

Article

Fast‐acting psychedelic shows antidepressant effects in Phase 2A trial.

Published in:: Brown University Psychopharmacology Update, 2025, v. 36, n. 8, p. 7, doi. 10.1002/pu.31340
Publication type:: Article

A phase 0, window of opportunity study of parasympathetic stimulation with bethanechol in localized pancreatic adenocarcinoma prior to surgery.

Published in:

Oncologist, 2025, v. 30, n. 6, p. 1, doi. 10.1093/oncolo/oyaf162

By:

White, Ruth A;
Mezzano-Robinson, Valeria;
Shi, Qiongyu;
Kuriakose, Nadine;
Schrope, Beth;
Kluger, Michael D;
Sugahara, Kazuki;
Chabot, John;
Manji, Gulam;
Oberstein, Paul;
Remotti, Helen;
Wang, Timothy C;
Bates, Susan E

Publication type:

Article

Phase I trial of SPH4336, a novel cyclin-dependent kinase 4/6 inhibitor, in patients with advanced solid tumors.

Published in:

Oncologist, 2025, v. 30, n. 6, p. 1, doi. 10.1093/oncolo/oyaf077

By:

Jiang, Yu;
Liang, Xu;
Sun, Mei-Li;
Gao, Ge;
Gong, Yi;
Li, Hui-Ping;
Liu, Jie;
Wang, Yong-Sheng

Publication type:

Article

Use of tirzepatide (Mounjaro) in type 2 diabetes management: an overview.

Published in:

Nursing Standard, 2025, v. 40, n. 7, p. 47, doi. 10.7748/ns.2025.e12464

By:

Davies, Claire

Publication type:

Article

On the front lines of cardiovascular-kidney-metabolic syndrome: Review of GLP-1 and Dual GLP-1/GIP receptor agonists in CV and kidney health.

Published in:

American Journal of Health-System Pharmacy, 2025, v. 82, n. 13, p. 693, doi. 10.1093/ajhp/zxaf053

By:

Salama, Lavinia;
Sinn, Levi

Publication type:

Article

Clinical effects of methylphenidate hydrochloride extended-release tablets on improvement of intelligence and behavior in children with attention deficit hyperactivity disorder.

Published in:

African Journal of Reproductive Health, 2025, v. 29, n. 6, p. 141, doi. 10.29063/ajrh2025/v29i6.13

By:

Wenjin Huang;
Yanyan Wang

Publication type:

Article

Anticancer Potential of β-Sitosterol: A Comprehensive Exploration of Mechanisms and Therapeutic Prospects.

Published in:

American Journal of Chinese Medicine, 2025, v. 53, n. 4, p. 1241, doi. 10.1142/S0192415X2550048X

By:

Zhang, Yuzhe;
Yang, Chunjiao;
Guo, Junhan;
Yan, Lirong;
Li, Yanke;
Zhang, Ye

Publication type:

Article

Evodiamine Suppresses Lung Cancer Progression Through Modulating FAK/STAT3/AKT Signaling Pathway.

Published in:

American Journal of Chinese Medicine, 2025, v. 53, n. 4, p. 1225, doi. 10.1142/S0192415X25500478

By:

Yuan, Wen-Xin;
Chen, Wen;
Hu, Ping;
Huang, Qian-Wen;
Li, Le-Hui;
Yang, Hong;
Zhang, Wei;
Tang, Jian-Jun;
Sun, Long-Hua

Publication type:

Article

Celastrol Alleviates Intestinal Epithelial Permeability by Inhibiting Ferroptosis through PI3K/Akt/FOXO1/HO-1 Signaling Pathway.

Published in:

American Journal of Chinese Medicine, 2025, v. 53, n. 4, p. 1207, doi. 10.1142/S0192415X25500466

By:

Wu, Dan;
Shi, Ping;
Tang, Lian-Hua;
Song, Xiao-Mei;
Deng, Juan;
Guo, Hong;
Yin, Fei

Publication type:

Article

Valeriana Jatamansi: An Overview of Phytochemistry, Pharmacology, Clinical Prospects, and Network Analysis of Drug Targets.

Published in:

American Journal of Chinese Medicine, 2025, v. 53, n. 4, p. 1027, doi. 10.1142/S0192415X25500399

By:

Zhao, Siyu;
Ji, Xiaoyun;
Li, Junxian;
Han, Delong;
Yang, Lijiao;
Huang, Yushen;
Tan, Rui;
Yan, Zhiyong;
Jiang, Hezhong

Publication type:

Article

Calcium/Calmodulin‐Dependent Protein Kinase II Inhibitors Mitigate High‐Fat Diet–Induced Obesity in Mice.

Published in:

Journal of Obesity, 2025, v. 2025, p. 1, doi. 10.1155/jobe/5530467

By:

Kawao, Naoyuki;
Satoh, Ryosuke;
Mizukami, Yuya;
Okumoto, Katsumi;
Tanabe, Genzoh;
Muraoka, Osamu;
Sugiura, Reiko;
Kaji, Hiroshi;
Claire, Stocker

Publication type:

Article

Quasipaa spinosa-Derived Parvalbumin Attenuates Exercise-Induced Fatigue via Calcium Homeostasis and Oxidative Stress Modulation in Exhaustively Trained Mice.

Published in:

Nutrients, 2025, v. 17, n. 12, p. 2043, doi. 10.3390/nu17122043

By:

Sang, Kai;
Lu, Congfei;
Zhang, Yangfan;
Chen, Qi

Publication type:

Article