Works about PARKIN (Protein)

Results: 272

PINK1 protects against dendritic cell dysfunction during sepsis through the regulation of mitochondrial quality control.

Published in:

Molecular Medicine, 2023, v. 29, n. 1, p. 1, doi. 10.1186/s10020-023-00618-5

By:

Wu, You;
Chen, Longwang;
Qiu, Zhimin;
Zhang, Xijing;
Zhao, Guangju;
Lu, Zhongqiu

Publication type:

Article

Pink1-Mediated Chondrocytic Mitophagy Contributes to Cartilage Degeneration in Osteoarthritis.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 11, p. 1849, doi. 10.3390/jcm8111849

By:

Shin, Hyo Jung;
Park, Hyewon;
Shin, Nara;
Kwon, Hyeok Hee;
Yin, Yuhua;
Hwang, Jeong-Ah;
Song, Hee-Jung;
Kim, Jinhyun;
Kim, Dong Woon;
Beom, Jaewon

Publication type:

Article

Alantolactone induces apoptosis through ROS-mediated AKT pathway and inhibition of PINK1-mediated mitophagy in human HepG2 cells.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2019, v. 47, n. 1, p. 1961, doi. 10.1080/21691401.2019.1593854

By:

Kang, Xing;
Wang, Hijuan;
Li, Yanwei;
Xiao, Ying;
Zhao, Lili;
Zhang, Tingting;
Zhou, Shaohe;
Zhou, Xiaolun;
Li, Yi;
Shou, Zhexing;
Chen, Chao;
Li, Bin

Publication type:

Article

Effect of PINK1 and Parkin gene silencing on sodium arsenite-induced mitophagy in normal rat liver cells (BRL-3A).

Published in:

Toxicology Research, 2022, v. 11, n. 1, p. 52, doi. 10.1093/toxres/tfab110

By:

Hu, Ting;
Wu, Changyan;
Jian, Wen;
Wu, Liping;
Zuo, Peipei;
Zeng, Qibing;
Luo, Peng

Publication type:

Article

Activation of parkin by a molecular glue.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51889-3

By:

Sauvé, Véronique;
Stefan, Eric;
Croteau, Nathalie;
Goiran, Thomas;
Fakih, Rayan;
Bansal, Nupur;
Hadzipasic, Adelajda;
Fang, Jing;
Murugan, Paramasivam;
Chen, Shimin;
Fon, Edward A.;
Hirst, Warren D.;
Silvian, Laura F.;
Trempe, Jean-François;
Gehring, Kalle

Publication type:

Article

β-amyloid protein induces mitophagy-dependent ferroptosis through the CD36/PINK/PARKIN pathway leading to blood–brain barrier destruction in Alzheimer's disease.

Published in:

Cell & Bioscience, 2022, v. 12, n. 1, p. 1, doi. 10.1186/s13578-022-00807-5

By:

Li, Jianhua;
Li, Mengyu;
Ge, Yangyang;
Chen, Jiayi;
Ma, Jiamin;
Wang, Chenchen;
Sun, Miaomiao;
Wang, Li;
Yao, Shanglong;
Yao, Chengye

Publication type:

Article

A novel treatment alternative in cisplatin-induced neuropathy: low intensity pulsed ultrasound.

Published in:

Anatomy: International Journal of Experimental & Clinical Anatomy, 2020, v. 14, p. S113

By:

Yıldız, Büşra Bilir;
Girit, Özlem Bozkurt;
Bilgin, Mehmet Dinçer

Publication type:

Article

Electroacupuncture at GV20-GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis.

Published in:

Molecular Medicine Reports, 2021, v. 24, n. 1, p. N.PAG

By:

Guan, Ruiqiao;
Li, Zhihao;
Dai, Xiaohong;
Zou, Wei;
Yu, Xueping;
Liu, Hao;
Chen, Qiuxin;
Teng, Wei;
Liu, Peng;
Liu, Xiaoying;
Dong, Shanshan

Publication type:

Article

Parkin deficiency elevates hepatic ischemia/reperfusion injury accompanying decreased mitochondrial autophagy, increased apoptosis, impaired DNA damage repair and altered cell cycle distribution.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 6, p. 5663, doi. 10.3892/mmr.2018.9606

By:

Ning, Xiao-Jie;
Yan, Xiong;
Wang, Yan-Feng;
Wang, Ren;
Fan, Xiao-Li;
Zhong, Zi-Biao;
Ye, Qi-Fa

Publication type:

Article

Liraglutide repairs the infarcted heart: The role of the SIRT1/Parkin/mitophagy pathway.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 3, p. 3722, doi. 10.3892/mmr.2018.8371

By:

Qiao, Huiying;
REN, Haiyan;
Du, He;
Zhang, Minfang;
Xiong, Xiaofang;
Lv, Rong

Publication type:

Article

Deconstructing the molecular genetics behind the PINK1/Parkin axis in Parkinson's disease using Drosophila melanogaster as a model organism.

Published in:

Egyptian Journal of Medical Human Genetics, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s43042-021-00208-2

By:

Ganesan, Suchita;
Parvathi, Venkatachalam Deepa

Publication type:

Article

MiR-181c-5p Regulates Lung Adenocarcinoma Progression via Targeting PRKN.

Published in:

Biochemical Genetics, 2024, v. 62, n. 2, p. 1103, doi. 10.1007/s10528-023-10459-w

By:

Wang, Jing;
Li, Man;
Wang, Meigui;
Yang, Jing;
Li, Deguang;
Hao, Yunxia

Publication type:

Article

Effect of the Porcine STC-1 Gene on Autophagy and Mitochondrial Function as Induced by Serum Starvation.

Published in:

Biochemical Genetics, 2022, v. 60, n. 6, p. 2533, doi. 10.1007/s10528-022-10233-4

By:

Wang, Hao;
Yang, Yuefei;
Wang, Yi;
Peng, Yuehan;
Xu, Lei;
Hu, Yuemin;
Ju, Huiming

Publication type:

Article

Analysis of α-syn and parkin interaction in mediating neuronal death in Drosophila model of Parkinson’s disease.

Published in:

Frontiers in Cellular Neuroscience, 2024, p. 1, doi. 10.3389/fncel.2023.1295805

By:

Narwal, Sonia;
Singh, Amit;
Tare, Meghana

Publication type:

Article

Loss of HIPK2 Protects Neurons from Mitochondrial Toxins by Regulating Parkin Protein Turnover.

Published in:

Journal of Neuroscience, 2020, v. 40, n. 3, p. 557, doi. 10.1523/JNEUROSCI.2017-19.2019

By:

Jiasheng Zhang;
Yulei Shang;
Kamiya, Sherry;
Kotowski, Sarah J.;
Ken Nakamura;
Huang, Eric J.

Publication type:

Article

Seeking an In Vivo Neuronal Context for the PINK1/Parkin Pathway.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 44, p. 11165, doi. 10.1523/JNEUROSCI.2525-16.2016

By:

Ader, Nicholas R.

Publication type:

Article

Mitochondrial Quality Control via the PGC1α-TFEB Signaling Pathway Is Compromised by Parkin Q311X Mutation But Independently Restored by Rapamycin.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 37, p. 12833, doi. 10.1523/JNEUROSCI.0109-15.2015

By:

Siddiqui, Almas;
Bhaumik, Dipa;
Chinta, Shankar J.;
Rane, Anand;
Rajagopalan, Subramanian;
Lieu, Christopher A.;
Lithgow, Gordon J.;
Andersen, Julie K.

Publication type:

Article

Upregulation of Parkin in Endophilin Mutant Mice.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 49, p. 16544, doi. 10.1523/JNEUROSCI.1710-14.2014

By:

Mian Cao;
Milosevic, Ira;
Giovedi, Silvia;
De Camilli, Pietro

Publication type:

Article

Upregulated Parkin expression protects mitochondrial homeostasis in DJ-1 konckdown cells and cells overexpressing the DJ-1 L166P mutation.

Published in:

Molecular & Cellular Biochemistry, 2014, v. 387, n. 1/2, p. 187, doi. 10.1007/s11010-013-1884-3

By:

Chang, Chunyan;
Wu, Guolu;
Gao, Peiye;
Yang, Ling;
Liu, Wen;
Zuo, Ji

Publication type:

Article

Parkin modulates expression of HIF-1α and HIF-3α during hypoxia in gliobastoma-derived cell lines in vitro.

Published in:

Cell & Tissue Research, 2016, v. 364, n. 3, p. 465, doi. 10.1007/s00441-015-2340-3

By:

Maugeri, Grazia;
D'Amico, Agata;
Reitano, Rita;
Saccone, Salvatore;
Federico, Concetta;
Cavallaro, Sebastiano;
D'Agata, Velia

Publication type:

Article

Effects of eight weeks of high-intensity interval training on the expression of Pink1 and Parkin proteins in the liver tissue of type 2 diabetic male rats.

Published in:

Journal of Sport & Exercise Physiology (JSEP) / Fīziyuluzhī-i Varzish va Fa̒āliyyat-i Badanī, 2023, v. 16, n. 3, p. 101, doi. 10.48308/joeppa.2023.103909

By:

Vakili, Javad;
Sarraf, Vahid Sari;
Khazaei, Sara Farajpour

Publication type:

Article

A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 targets.

Published in:

Communications Biology, 2020, v. 3, n. 1, p. N.PAG, doi. 10.1038/s42003-020-01328-y

By:

Watanabe, Masashi;
Saeki, Yasushi;
Takahashi, Hidehisa;
Ohtake, Fumiaki;
Yoshida, Yukiko;
Kasuga, Yusuke;
Kondo, Takeshi;
Yaguchi, Hiroaki;
Suzuki, Masanobu;
Ishida, Hiroki;
Tanaka, Keiji;
Hatakeyama, Shigetsugu

Publication type:

Article

Correction to: A case of childhood‑onset dystonia‑parkinsonism due to homozygous parkin mutations and effect of globus pallidus deep brain stimulation.

Published in:

2023

By:

Garrì, Federica;
Ciprietti, Dario;
Lerjefors, Lisa;
Landi, Andrea;
Pilleri, Manuela;
Biundo, Roberta;
Salviati, Leonardo;
Carecchio, Miryam;
Antonini, Angelo

Publication type:

Correction Notice

A case of childhood-onset dystonia-parkinsonism due to homozygous parkin mutations and effect of globus pallidus deep brain stimulation.

Published in:

Neurological Sciences, 2023, v. 44, n. 9, p. 3323, doi. 10.1007/s10072-023-06832-7

By:

Garrì, Federica;
Ciprietti, Dario;
Lerjefors, Lisa;
Landi, Andrea;
Pilleri, Manuela;
Biundo, Roberta;
Salviati, Leonardo;
Carecchio, Miryam;
Antonini, Angelo

Publication type:

Article

15-Year Subthalamic Deep Brain Stimulation outcome in a Parkinson's disease patient with Parkin gene mutation: a case report.

Published in:

Neurological Sciences, 2023, v. 44, n. 8, p. 2939, doi. 10.1007/s10072-023-06789-7

By:

Covolo, Anna;
Imbalzano, Gabriele;
Artusi, Carlo Alberto;
Montanaro, Elisa;
Ledda, Claudia;
Bozzali, Marco;
Rizzone, Mario Giorgio;
Zibetti, Maurizio;
Martone, Tiziana;
Lopiano, Leonardo;
Romagnolo, Alberto

Publication type:

Article

PARK2 presenting as a disabling peripheral axonal neuropathy.

Published in:

2015

By:

Domingos, Joana;
Coelho, Teresa;
Taipa, Ricardo;
Basto, Jorge;
Melo-Pires, Manuel;
Magalhães, Marina

Publication type:

Letter

Impaired Mitochondrial Network Morphology and Reactive Oxygen Species Production in Fibroblasts from Parkinson's Disease Patients.

Published in:

Biomedicines, 2024, v. 12, n. 2, p. 282, doi. 10.3390/biomedicines12020282

By:

Kritskaya, Kristina A.;
Fedotova, Evgeniya I.;
Berezhnov, Alexey V.

Publication type:

Article

Parkin Promotes Airway Inflammatory Response to Interferon Gamma.

Published in:

Biomedicines, 2023, v. 11, n. 10, p. 2850, doi. 10.3390/biomedicines11102850

By:

Dimasuay, Kris Genelyn;
Schaunaman, Niccolette;
Berg, Bruce;
Nichols, Taylor;
Chu, Hong Wei

Publication type:

Article

PINK1 and Parkin Ameliorate the Loss of Motor Activity and Mitochondrial Dysfunction Induced by Peripheral Neuropathy-Associated HSPB8 Mutants in Drosophila Models.

Published in:

Biomedicines, 2023, v. 11, n. 3, p. 832, doi. 10.3390/biomedicines11030832

By:

Kang, Kyong-hwa;
Han, Ji Eun;
Kim, Hyunjin;
Kim, Sohee;
Hong, Young Bin;
Yun, Jeanho;
Nam, Soo Hyun;
Choi, Byung-Ok;
Koh, Hyongjong

Publication type:

Article

Early Dysfunction of Substantia Nigra Dopamine Neurons in the ParkinQ311X Mouse.

Published in:

Biomedicines, 2021, v. 9, n. 5, p. 514, doi. 10.3390/biomedicines9050514

By:

Regoni, Maria;
Zanetti, Letizia;
Comai, Stefano;
Mercatelli, Daniela;
Novello, Salvatore;
Albanese, Federica;
Croci, Laura;
Consalez, Gian Giacomo;
Ciammola, Andrea;
Valtorta, Flavia;
Morari, Michele;
Sassone, Jenny;
Ekker, Marc

Publication type:

Article

Pink1/Parkin deficiency alters circulating lymphocyte populations and increases platelet-T cell aggregates in rats.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-74775-w

By:

Manganaro, Jane E.;
Emanuel, Katy;
Lamberty, Benjamin G.;
George, Joseph W.;
Stauch, Kelly L.

Publication type:

Article

Chronic replication stress invokes mitochondria dysfunction via impaired parkin activity.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-58656-w

By:

Kawabata, Tsuyoshi;
Sekiya, Reiko;
Goto, Shinji;
Li, Tao-Sheng

Publication type:

Article

USP8 Down-Regulation Promotes Parkin-Independent Mitophagy in the Drosophila Brain and in Human Neurons.

Published in:

Cells (2073-4409), 2023, v. 12, n. 8, p. 1143, doi. 10.3390/cells12081143

By:

Mauri, Sofia;
Bernardo, Greta;
Martinez, Aitor;
Favaro, Mariavittoria;
Trevisan, Marta;
Cobraiville, Gael;
Fillet, Marianne;
Caicci, Federico;
Whitworth, Alexander J.;
Ziviani, Elena

Publication type:

Article

Interaction of a Novel Alternatively Spliced Variant of HSD11B1L with Parkin Enhances the Carcinogenesis Potential of Glioblastoma: Peiminine Interferes with This Interaction.

Published in:

Cells (2073-4409), 2023, v. 12, n. 6, p. 894, doi. 10.3390/cells12060894

By:

Fu, Ru-Huei;
Hong, Syuan-Yu;
Tsai, Chia-Wen;
Liu, Shih-Ping;
Chiu, Shao-Chih;
Wu, Meng-Zhen;
Shyu, Woei-Cherng;
Lin, Shinn-Zong

Publication type:

Article

Role of Deubiquitinases in Parkinson's Disease—Therapeutic Perspectives.

Published in:

Cells (2073-4409), 2023, v. 12, n. 4, p. 651, doi. 10.3390/cells12040651

By:

Nielsen, Pernille Y. Ø.;
Okarmus, Justyna;
Meyer, Morten

Publication type:

Article

Mitophagy: Molecular Mechanisms, New Concepts on Parkin Activation and the Emerging Role of AMPK/ULK1 Axis.

Published in:

Cells (2073-4409), 2022, v. 11, n. 1, p. 30, doi. 10.3390/cells11010030

By:

Iorio, Roberto;
Celenza, Giuseppe;
Petricca, Sabrina

Publication type:

Article

Parkin beyond Parkinson's Disease—A Functional Meaning of Parkin Downregulation in TDP-43 Proteinopathies.

Published in:

Cells (2073-4409), 2021, v. 10, n. 12, p. 3389, doi. 10.3390/cells10123389

By:

Gaweda-Walerych, Katarzyna;
Sitek, Emilia Jadwiga;
Narożańska, Ewa;
Buratti, Emanuele

Publication type:

Article

Disruption of Mitochondrial Homeostasis: The Role of PINK1 in Parkinson's Disease.

Published in:

Cells (2073-4409), 2021, v. 10, n. 11, p. 3022, doi. 10.3390/cells10113022

By:

Vizziello, Maria;
Borellini, Linda;
Franco, Giulia;
Ardolino, Gianluca

Publication type:

Article

Evaluation of PARKIN gene variants in West Bengal Parkinson's disease patients.

Published in:

Journal of Human Genetics, 2015, v. 60, n. 9, p. 485, doi. 10.1038/jhg.2015.49

By:

Sanyal, Jaya;
Jana, Arpita;
Ghosh, Epsita;
Banerjee, Tapas K;
Chakraborty, Durga P;
Rao, Vadlamudi R

Publication type:

Article

Functional Role of Parkin against Oxidative Stress in Neural Cells.

Published in:

Endocrinology & Metabolism, 2014, v. 29, n. 1, p. 62, doi. 10.3803/EnM.2014.29.1.62

By:

Minyoung Hwang;
Ja-Myong Lee;
Younghwa Kim;
Dongho Geum

Publication type:

Article

Role of Parkin and endurance training on mitochondrial turnover in skeletal muscle.

Published in:

Skeletal Muscle, 2018, v. 8, p. 1, doi. 10.1186/s13395-018-0157-y

By:

Chen, Chris Chin Wah;
Erlich, Avigail T.;
Hood, David A.

Publication type:

Article

Phosphatase and tensin homolog-induced putative kinase 1 and Parkin in diabetic heart: Role of mitophagy.

Published in:

Journal of Diabetes Investigation, 2015, v. 6, n. 3, p. 250, doi. 10.1111/jdi.12302

By:

Tang, Ying;
Liu, Jiankang;
Long, Jiangang

Publication type:

Article

Advances in Mitochondria-Targeted Drug Delivery.

Published in:

Pharmaceutics, 2023, v. 15, n. 8, p. 2089, doi. 10.3390/pharmaceutics15082089

By:

Bottani, Emanuela;
Brunetti, Dario

Publication type:

Article

PARK2 Mediates Interleukin 6 and Monocyte Chemoattractant Protein 1 Production by Human Macrophages.

Published in:

PLoS Neglected Tropical Diseases, 2013, v. 7, n. 1, p. 1, doi. 10.1371/journal.pntd.0002015

By:

de Léséleuc, Louis;
Orlova, Marianna;
Cobat, Aurelie;
Girard, Manon;
Huong, Nguyen Thu;
Ba, Nguyen Ngoc;
Van Thuc, Nguyen;
Truman, Richard;
Spencer, John S.;
Adams, Linda;
Thai, Vu Hong;
Alcais, Alexandre;
Schurr, Erwin

Publication type:

Article

The Transcription Factor Function of Parkin: Breaking the Dogma.

Published in:

Frontiers in Neuroscience, 2019, p. N.PAG, doi. 10.3389/fnins.2018.00965

By:

Alves da Costa, Cristine;
Duplan, Eric;
Rouland, Lila;
Checler, Frédéric

Publication type:

Article

Parkin is a critical player in the effects of caffeine over mitochondrial quality control pathways during skeletal muscle regeneration in mice.

Published in:

Acta Physiologica, 2024, v. 240, n. 3, p. 1, doi. 10.1111/apha.14111

By:

Esteca, M. V.;
Divino, I. A.;
Vieira da Silva, A. L.;
Severino, M. B.;
Braga, R. R.;
Ropelle, E. R.;
Simabuco, F. M.;
Baptista, I. L.

Publication type:

Article

Parkin Is Dispensable for Mitochondrial Function, but Its Ubiquitin Ligase Activity Is Critical for Macroautophagy and Neurotransmitters: Therapeutic Potential beyond Parkinson's Disease.

Published in:

Neurodegenerative Diseases, 2015, v. 15, n. 5, p. 259, doi. 10.1159/000430888

By:

Moussa, Charbel E.-H.

Publication type:

Article

Parkin Plays a Role in Sporadic Parkinson's Disease.

Published in:

Neurodegenerative Diseases, 2014, v. 13, n. 2/3, p. 69, doi. 10.1159/000354307

By:

Dawson, Ted M.;
Dawson, Valina L.

Publication type:

Article

Interplay between Parkin and p53 Governs a Physiological Homeostasis That Is Disrupted in Parkinson's Disease and Cerebral Cancer.

Published in:

Neurodegenerative Diseases, 2014, v. 13, n. 2/3, p. 118, doi. 10.1159/000354075

By:

Checler, F.;
Alves da Costa, C.

Publication type:

Article

Parkin: Much More than a Simple Ubiquitin Ligase.

Published in:

Neurodegenerative Diseases, 2012, v. 10, n. 1-4, p. 49, doi. 10.1159/000332803

By:

Alves da Costa, C.;
Checler, F.

Publication type:

Article