Works about P-glycoprotein

Results: 2427

Spice components as modulating agents of P-glycoprotein - An in silico study.

Published in:

Indian Journal of Pharmacology, 2024, v. 56, n. 3, p. 214, doi. 10.4103/ijp.ijp_299_23

By:

Mukhopadhyay, Swagata;
Roy, Chandana;
Ghosh, Pratiti

Publication type:

Article

Study of fingolimod, nitric oxide inhibitor, and P-glycoprotein inhibitor in modulating the P-glycoprotein expression via an endothelin-sphingolipid pathway in an animal model of pharmacoresistant epilepsy.

Published in:

Indian Journal of Pharmacology, 2023, v. 55, n. 5, p. 307, doi. 10.4103/ijp.ijp_100_23

By:

Garg, Nitika;
Joshi, Rupa;
Bhatia, Alka;
Bansal, Seema;
Chakrabarti, Amitava;
Prakash, Ajay;
Saikia, Biman;
Modi, Manish;
Medhi, Bikash

Publication type:

Article

Up-regulation of P-glycoprotein expression by catalase via JNK activation in HepG2 cells.

Published in:

Redox Report, 2006, v. 11, n. 4, p. 173, doi. 10.1179/135100006X116682

By:

Li, Lin;
Xu, Jianfeng;
Min, Taishan;
Huang, Weida

Publication type:

Article

Development of Natural‐Product‐Inspired ABCB1 Inhibitors Through Regioselective Tryptophan C3‐Benzylation.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 63, p. 1, doi. 10.1002/chem.202401782

By:

Mariya Vincent, Dona;
Mostafa, Habib;
Suneer, Anza;
Radha Krishnan, Sabhashina;
Ong, Mingmin;
Itahana, Yoko;
Itahana, Koji;
Viswanathan, Rajesh

Publication type:

Article

Controllable Generation of Nitric Oxide by Near-Infrared-Sensitized Upconversion Nanoparticles for Tumor Therapy.

Published in:

Advanced Functional Materials, 2015, v. 25, n. 20, p. 3049, doi. 10.1002/adfm.201404402

By:

Zhang, Xiao;
Tian, Gan;
Yin, Wenyan;
Wang, Liming;
Zheng, Xiaopeng;
Yan, Liang;
Li, Jinxia;
Su, Haoran;
Chen, Chunying;
Gu, Zhanjun;
Zhao, Yuliang

Publication type:

Article

Influence of eight ABCB1 polymorphisms on antidepressant response in a prospective cohort of treatment‐free Russian patients with moderate or severe depression: An explorative psychopharmacological study with naturalistic design.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2022, v. 37, n. 3, p. 1, doi. 10.1002/hup.2826

By:

Geers, Lisanne M.;
Ochi, Taichi;
Vyalova, Natalya M.;
Losenkov, Innokentiy S.;
Paderina, Diana Z.;
Pozhidaev, Ivan V.;
Simutkin, German G.;
Bokhan, Nikolay A.;
Wilffert, Bob;
Touw, Daniël J.;
Loonen, Anton J.M.;
Ivanova, Svetlana A.

Publication type:

Article

In vitro and in vivo evaluation of the effects of duloxetine on P-gp function.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2010, v. 25, n. 7/8, p. 553, doi. 10.1002/hup.1152

By:

Zhao Ruike;
Cao Junhua;
Peng Wenxing

Publication type:

Article

Venlafaxine induces P-glycoprotein in human Caco-2 cells.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2007, v. 22, n. 1, p. 49, doi. 10.1002/hup.820

By:

Ehret, M. J.;
Levin, G. M.;
Narasimhan, M.;
Rathinavelu, A.

Publication type:

Article

P-glycoprotein interaction with risperidone and 9-OH-risperidone studied in vitro, in knock-out mice and in drug–drug interaction experiments.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2005, v. 20, n. 7, p. 493, doi. 10.1002/hup.720

By:

Ejsing, Thomas B.;
Pedersen, Anne D.;
Linnet, Kristian

Publication type:

Article

Do drug transporter ( ABCB1) SNPs and P-glycoprotein function influence cyclosporine and macrolides exposure in renal transplant patients? Results of the pharmacogenomic substudy within the symphony study.

Published in:

Transplant International, 2013, v. 26, n. 2, p. 177, doi. 10.1111/tri.12018

By:

Llaudó, Inés;
Colom, Helena;
Giménez-Bonafé, Pepita;
Torras, Joan;
Caldés, Anna;
Sarrias, Maria;
Cruzado, Josep Mª;
Oppenheimer, Federico;
Sánchez-Plumed, Jaime;
Gentil, Miguel Ángel;
Ekberg, Henrik;
Grinyó, Josep Mª;
Lloberas, Núria

Publication type:

Article

Abstracts (pages 6-10).

Published in:: Naunyn-Schmiedeberg's Archives of Pharmacology, 2004, v. 369, p. 6, doi. 10.1007/s00210-004-0887-8
Publication type:: Article

Impact of genetic polymorphisms in transmembrane carrier-systems on drug and xenobiotic distribution.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2004, v. 369, n. 1, p. 69, doi. 10.1007/s00210-003-0813-5

By:

Gerloff, Thomas

Publication type:

Article

Abstracts (pages 8-14).

Published in:: 2003
Publication type:: Abstract

Interaction of omeprazole, lansoprazole and pantoprazole with P-glycoprotein.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2001, v. 364, n. 6, p. 551, doi. 10.1007/s00210-001-0489-7

By:

Pauli-Magnus, Christiane;
Rekersbrink, Sabine;
Klotz, Ulrich;
Fromm, Martin F.

Publication type:

Article

P-glycoprotein-mediated transport of digitoxin, α-methyldigoxin and β-acetyldigoxin.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2001, v. 363, n. 3, p. 337, doi. 10.1007/s002100000354

By:

Pauli-Magnus, Christiane;
Mördter, Thomas;
Godel, Andrea;
Mettang, Thomas;
Eichelbaum, Michel;
Klotz, Ulrich;
Fromm, Martin F.

Publication type:

Article

Characterization of the transport of the organic cation [<sup>3</sup>H]MPP<sup>+</sup> in human intestinal epithelial (Caco-2) cells.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2000, v. 361, n. 5, p. 505, doi. 10.1007/s002100000223

By:

Martel, F.;
Calhau, C.;
Azevedo, I.

Publication type:

Article

A new method to measure intestinal activity of P-glycoprotein in avian and mammalian species.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2005, v. 175, n. 1, p. 57, doi. 10.1007/s00360-004-0462-0

By:

Green, Adam K.;
Barnes, David M.;
Karasov, William H.

Publication type:

Article

P-glycoprotein-like protein contributes to cadmium resistance in Euglena gracilis.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2003, v. 173, n. 7, p. 559, doi. 10.1007/s00360-003-0365-5

By:

Einicker-Lamas, M.;
Morales, M. M.;
Miranda, K.;
Garcia-Abreu, J.;
Oliveira, A. J. F.;
Silva, F. L. S.;
Oliveira, M. M.

Publication type:

Article

Accumulation and distribution of doxorubicin in tumour spheroids: the influence of acidity and expression of P-glycoprotein.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1179, doi. 10.1007/s00280-011-1598-8

By:

Mellor, Howard;
Callaghan, Richard

Publication type:

Article

Interaction potential of the endothelin-A receptor antagonist atrasentan with drug transporters and drug-metabolising enzymes assessed in vitro.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 4, p. 1093, doi. 10.1007/s00280-011-1715-8

By:

Weiss, Johanna;
Haefeli, Walter

Publication type:

Article

H1, a novel derivative of tetrandrine reverse P-glycoprotein-mediated multidrug resistance by inhibiting transport function and expression of P-glycoprotein.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 67, n. 5, p. 1017, doi. 10.1007/s00280-010-1397-7

By:

Wei, Ning;
Sun, Hua;
Wang, Fengpeng;
Liu, Gengtao

Publication type:

Article

Wogonin potentiates the antitumor action of etoposide and ameliorates its adverse effects.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 67, n. 5, p. 1063, doi. 10.1007/s00280-010-1396-8

By:

Enomoto, Riyo;
Koshiba, Chika;
Suzuki, Chie;
Lee, Eibai

Publication type:

Article

PXR-mediated induction of P-glycoprotein by anticancer drugs in a human colon adenocarcinoma-derived cell line.

Published in:

Cancer Chemotherapy & Pharmacology, 2010, v. 66, n. 4, p. 765, doi. 10.1007/s00280-009-1221-4

By:

Harmsen, Stefan;
Meijerman, I.;
Febus, C. L.;
Maas-Bakker, R. F.;
Beijnen, J. H.;
Schellens, J. H. M.

Publication type:

Article

Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce apoptosis in multi-drug-resistant cancer cells.

Published in:

Cancer Chemotherapy & Pharmacology, 2010, v. 66, n. 3, p. 585, doi. 10.1007/s00280-009-1200-9

By:

Nathwani, Seema-Maria;
Butler, Stephen;
Fayne, Darren;
McGovern, Naomi N.;
Sarkadi, Balazs;
Meegan, Mary J.;
Lloyd, David G.;
Campiani, Giuseppe;
Lawler, Mark;
Williams, D. Clive;
Zisterer, Daniela M.

Publication type:

Article

MDR1 C2005T polymorphism changes substrate specificity.

Published in:

Cancer Chemotherapy & Pharmacology, 2010, v. 66, n. 3, p. 617, doi. 10.1007/s00280-010-1308-y

By:

Lijuan Liu;
Lan Fan;
Xiangdong Peng;
Dongli Hu;
Honghao Zhou

Publication type:

Article

Inhibition of P-glycoprotein and multidrug resistance protein 1 by dietary phytochemicals.

Published in:

Cancer Chemotherapy & Pharmacology, 2008, v. 62, n. 5, p. 867, doi. 10.1007/s00280-007-0676-4

By:

Nabekura, Tomohiro;
Yamaki, Takeshi;
Ueno, Kazuyuki;
Kitagawa, Shuji

Publication type:

Article

A phase II study of milataxel: a novel taxane analogue in previously treated patients with advanced colorectal cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2008, v. 61, n. 3, p. 453, doi. 10.1007/s00280-007-0489-5

By:

Ramanathan, Ramesh K.;
Picus, Joel;
Raftopoulos, Haralambos;
Bernard, Stephen;
Lockhart, A. Craig;
Frenette, Gary;
Macdonald, John;
Melin, Susan;
Berg, Daniel;
Brescia, Frank;
Hochster, Howard;
Cohn, Allen

Publication type:

Article

Flavonoids inhibit breast cancer resistance protein-mediated drug resistance: transporter specificity and structure–activity relationship.

Published in:

Cancer Chemotherapy & Pharmacology, 2007, v. 60, n. 6, p. 789, doi. 10.1007/s00280-007-0426-7

By:

Katayama, Kazuhiro;
Masuyama, Kazuto;
Yoshioka, Sho;
Hasegawa, Hitomi;
Mitsuhashi, Junko;
Sugimoto, Yoshikazu

Publication type:

Article

Tetrandrine achieved plasma concentrations capable of reversing MDR in vitro and had no apparent effect on doxorubicin pharmacokinetics in mice.

Published in:

Cancer Chemotherapy & Pharmacology, 2007, v. 60, n. 5, p. 741, doi. 10.1007/s00280-007-0420-0

By:

Chun-LingDai;
Hui-Yu Xiong;
Li-Fen Tang;
Xu Zhang;
Yong-Ju Liang;
Mu-Sheng Zeng;
Li-Ming Chen;
Xiao-Hong Wang;
Li-Wu Fu

Publication type:

Article

Novel tetrahydroisoquinolin-ethyl-phenylamine based multidrug resistance inhibitors with broad-spectrum modulating properties.

Published in:

2007

By:

Jekerle, Veronika;
Klinkhammer, Werner;
Reilly, Raymond;
Piquette-Miller, Micheline;
Wiese, Michael;
Reilly, Raymond M

Publication type:

journal article

Molecular changes to HeLa cells on continuous exposure to cisplatin or paclitaxel.

Published in:

2006

By:

Takara, Kohji;
Obata, Yukihisa;
Yoshikawa, Eri;
Kitada, Noriaki;
Sakaeda, Toshiyuki;
Ohnishi, Noriaki;
Yokoyama, Teruyoshi

Publication type:

journal article

Dibenzocyclooctadiene lingnans: a class of novel inhibitors of P-glycoprotein.

Published in:

Cancer Chemotherapy & Pharmacology, 2006, v. 58, n. 1, p. 99, doi. 10.1007/s00280-005-0133-1

By:

Qiangrong Pan;
Qinghua Lu;
Kun Zhang;
Xun Hu

Publication type:

Article

The effect of P-glycoprotein and cytochrome P450 3a on the oral bioavailability of vinorelbine in mice.

Published in:

Cancer Chemotherapy & Pharmacology, 2006, v. 57, n. 6, p. 819, doi. 10.1007/s00280-005-0088-2

By:

Press, Rogier R.;
Buckle, Tessa;
Beijnen, Jos H.;
van Tellingen, Olaf

Publication type:

Article

Thalidomide does not interact with P-glycoprotein.

Published in:

Cancer Chemotherapy & Pharmacology, 2006, v. 57, n. 5, p. 599, doi. 10.1007/s00280-005-0087-3

By:

Zimmermann, Christian;
Gutmann, Heike;
Drewe, Juergen

Publication type:

Article

Investigation of the influence of modulation of P-glycoprotein by a multiple dosing regimen of tamoxifen on the pharmacokinetics and toxicodynamics of doxorubicin.

Published in:

Cancer Chemotherapy & Pharmacology, 2005, v. 56, n. 5, p. 497, doi. 10.1007/s00280-005-1001-8

By:

Darvari, Ramin;
Boroujerdi, Mehdi

Publication type:

Article

EM012, a microtubule-interfering agent, inhibits the progression of multidrug-resistant human ovarian cancer both in cultured cells and in athymic nude mice.

Published in:

Cancer Chemotherapy & Pharmacology, 2005, v. 55, n. 5, p. 461, doi. 10.1007/s00280-004-0903-1

By:

Jun Zhou;
Min Liu;
Luthra, Roopa;
Jones, Jeremy;
Aneja, Ritu;
Chandra, Ramesh;
Tekmal, Rajeshwar R.;
Joshi, Harish C.

Publication type:

Article

P-glycoprotein plays a role in the oral absorption of BMS-387032, a potent cyclin-dependent kinase 2 inhibitor, in rats.

Published in:

Cancer Chemotherapy & Pharmacology, 2005, v. 55, n. 2, p. 110, doi. 10.1007/s00280-004-0873-3

By:

Kamath, Amrita V.;
Saeho Chong;
Ming Chang;
Marathe, Punit

Publication type:

Article

Inhibition of P-glycoprotein activity and reversal of cancer multidrug resistance byMomordica charantiaextract.

Published in:

Cancer Chemotherapy & Pharmacology, 2004, v. 54, n. 6, p. 525, doi. 10.1007/s00280-004-0848-4

By:

Limtrakul, Pornngarm;
Khantamat, Orawan;
Pintha, Komsak

Publication type:

Article

Effect of cyclosporine A on the tissue distribution and pharmacokinetics of etoposide.

Published in:

Cancer Chemotherapy & Pharmacology, 2004, v. 54, n. 2, p. 153, doi. 10.1007/s00280-004-0784-3

By:

Cárcel-Trullols, Jaime;
Torres-Molina, Francisca;
Araico, Amparo;
Saadeddin, Anas;
Peris, José Esteban

Publication type:

Article

Three steps to cancer: how phosphorylation of tubulin, tubulin tyrosine ligase and P-glycoprotein may generate and sustain cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2004, v. 54, n. 2, p. 101, doi. 10.1007/s00280-004-0778-1

By:

Idriss, Haitham

Publication type:

Article

In vivo imaging of hepatobiliary transport function mediated by multidrug resistance associated protein and P-glycoprotein.

Published in:

Cancer Chemotherapy & Pharmacology, 2004, v. 54, n. 2, p. 131, doi. 10.1007/s00280-004-0793-2

By:

Hendrikse, N. Harry;
Kuipers, Folkert;
Meijer, Coby;
Havinga, Rick;
Bijleveld, Charles M. A.;
van der Graaf, Winette T. A.;
Vaalburg, Willem;
de Vries, Elisabeth G. E.

Publication type:

Article

Population pharmacokinetic model for daunorubicin and daunorubicinol coadministered with zosuquidar.3HCl (LY335979).

Published in:

Cancer Chemotherapy & Pharmacology, 2004, v. 54, n. 1, p. 39, doi. 10.1007/s00280-004-0775-4

By:

Callies, Sophie;
de Alwis, Dinesh P.;
Mehta, Atul;
Burgess, Michael;
Aarons, Leon

Publication type:

Article

Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 59-8862) and tRA96023.

Published in:

2004

By:

Minderman, Hans;
Brooks, Tracy A.;
O’Loughlin, Kieran L.;
Ojima, Iwao;
Bernacki, Ralph J.;
Baer, Maria R.;
O'Loughlin, Kieran L

Publication type:

journal article

Characterization of tetrandrine, a potent inhibitor of P-glycoprotein-mediated multidrug resistance.

Published in:

Cancer Chemotherapy & Pharmacology, 2004, v. 53, n. 4, p. 349, doi. 10.1007/s00280-003-0742-5

By:

Fu, Liwu;
Liang, Yongju;
Deng, Liwen;
Ding, Yan;
Chen, Liming;
Ye, Yanli;
Yang, Xiaoping;
Pan, Qichao

Publication type:

Article

P-glycoprotein expression does not change the apoptotic pathway induced by curcumin in HL-60 cells.

Published in:

Cancer Chemotherapy & Pharmacology, 2004, v. 53, n. 2, p. 179, doi. 10.1007/s00280-003-0705-x

By:

Bielak-Żmijewska, Anna;
Piwocka, Katarzyna;
Magalska, Adriana;
Sikora, Ewa

Publication type:

Article

Increased myelotoxicity of idarubicin: is there a pharmacological basis?: Results of a pharmacokinetic and an in vitro cytotoxicity study.

Published in:

Cancer Chemotherapy & Pharmacology, 2004, v. 53, n. 1, p. 61, doi. 10.1007/s00280-003-0700-2

By:

Kroschinsky, Frank;
Schleyer, Eberhard;
Renner, Ulf;
Schimming, Claudia;
Schimmelpfennig, Christoph;
Bornhäuser, Martin;
Illmer, Thomas;
Trümper, Lorenz;
Ehninger, Gerhard;
Schaich, Markus

Publication type:

Article

Phase I and pharmacokinetic study of vinblastine and high-dose megestrol acetate.

Published in:

Cancer Chemotherapy & Pharmacology, 2002, v. 50, n. 3, p. 179, doi. 10.1007/s00280-002-0484-9

By:

Matin, Khalid;
Egorin, Merrill J.;
Ballesteros, Michael F.;
Smith, David C.;
Lembersky, Barry;
Day, Roger S.;
Johnson, Candace S.;
Trump, Donald L.

Publication type:

Article

Influence of chemosensitizers on resistance mechanisms in daunorubicin-resistant Ehrlich ascites tumour cells.

Published in:

2002

By:

Nielsen, Dorte;
Eriksen, Jens;
Maare, Christian;
Friche, Ellen;
Skovsgaard, Torben

Publication type:

journal article

Selective modulation of P-glycoprotein's ATPase and anion efflux regulation activities with PKC alpha and PKC epsilon in Sf9 cells.

Published in:

2000

By:

Idriss, Haitham;
Urquidi, Virginia;
Basavappa, Srisaila;
Idriss, H;
Urquidi, V;
Basavappa, S

Publication type:

journal article

In vitro evaluation of newly developed chalcone analogues in human cancer cells.

Published in:

Cancer Chemotherapy & Pharmacology, 2000, v. 46, n. 4, p. 305, doi. 10.1007/s002800000160

By:

De Vincenzo, Rosa;
Ferlini, Cristiano;
Distefano, Mariagrazia;
Gaggini, Cristiana;
Riva, Antonella;
Bombardelli, Ezio;
Morazzoni, Paolo;
Valenti, Piero;
Belluti, Federica;
Ranelletti, Franco Oreste;
Mancuso, Salvatore;
Scambia, Giovanni

Publication type:

Article