Works about P-glycoprotein

Results: 2466

Influence of probiotics and deoxycholate on azathioprine transport in the PAMPA model: insights into pharmacomicrobiomics and interindividual variability in drug response.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1608110

By:

Đanić, Maja;
Pavlović, Nebojša;
Dedić, Natalija;
Zaklan, Dragana;
Lazarević, Slavica;
Stanimirov, Bojan;
Mikov, Momir

Publication type:

Article

Identification of the Notch ligand DLK1 as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60649-w

By:

Sun, Nai-Yun;
Kumar, Suresh;
Kim, Yoo Sun;
Varghese, Diana;
Mendoza, Arnulfo;
Nguyen, Rosa;
Okada, Reona;
Reilly, Karlyne;
Widemann, Brigitte;
Pommier, Yves;
Elloumi, Fathi;
Dhall, Anjali;
Taniyama, Daiki;
Patel, Mayank;
Aber, Etan;
Contreras, Cristina F.;
Kaplan, Rosandra N.;
Kiseljak-Vassiliades, Katja;
Wierman, Margaret E.;
Martinez, Dan

Publication type:

Article

P-glycoprotein expression skews mitochondrial dye measurements in T cells.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1560104

By:

Sok, Sophia P. M.;
Cheng, Jianan;
Strucinska, Klaudia;
Popescu, Narcis I.;
Wu, Lihua;
Ke, Qiuqing;
Kiosses, William B.;
Stanford, David;
Freeman, Willard M.;
Matsuzaki, Satoshi;
Lewis Jr., Tommy L.;
Zhao, Meng

Publication type:

Article

Effect of CYP2D6 and ABCB1 polymorphisms on pharmacokinetics and efficacy of aripiprazole in pediatric tic disorders.

Published in:

BMC Pediatrics, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12887-025-05856-6

By:

Xin, Yingying;
Gao, Liuliu;
Li, Sichan;
Wang, Jun;
Chen, Chen;
Tuo, Yali;
Nie, Gang;
Li, Ruizhen;
Sun, Dan;
Fu, Yongli;
Wang, Yang;
Liu, Zhisheng

Publication type:

Article

A Systematic Review of ABCB1 Polymorphisms and Antiseizure Medication Resistance: Insights from Effect Size and Study Power Analysis.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5548, doi. 10.3390/ijms26125548

By:

Daškevičiūtė, Aurelija;
Zaboras, Edgaras;
Navalinskas, Jonas;
Baronas, Karolis;
Jasionis, Arminas;
Navickienė, Eglė;
Mameniškienė, Rūta

Publication type:

Article

Investigation of the ABCB1 Gene Polymorphism and Food Effects on the Avatrombopag Pharmacokinetics in Chinese Individuals: A Population Pharmacokinetic/Pharmacodynamic Analysis.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 903, doi. 10.3390/ph18060903

By:

Liu, Xin;
Chen, Lulu;
Ju, Gehang;
Li, Chao;
Liu, Bijue;
Fei, Yunzhou;
Wang, Xintong;
Gao, Yang;
He, Qingfeng;
Zhu, Xiao;
Ouyang, Dongsheng

Publication type:

Article

Triple Non-Statin Therapy with Ezetimibe, Inclisiran, and Bempedoic Acid in Patients with Genetically Confirmed Statin-Induced Rhabdomyolysis: A Dual Case Report.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 818, doi. 10.3390/ph18060818

By:

Dodulík, Jozef;
Plášek, Jiří;
Kacířová, Ivana;
Uřinovská, Romana;
Vrtal, Jiří;
Václavík, Jan

Publication type:

Article

P-glycoprotein and multidrug resistance-associated protein 2 are oppositely altered in brain of rats with thioacetamide-induced acute liver failure.

Published in:

Liver International, 2013, v. 33, n. 2, p. 274, doi. 10.1111/j.1478-3231.2012.02862.x

By:

Jin, Shi;
Wang, Xin‐Ting;
Liu, Li;
Yao, Dan;
Liu, Can;
Zhang, Mian;
Guo, Hai‐Fang;
Liu, Xiao‐Dong

Publication type:

Article

Multidrug resistance 1 genotype and disposition of budesonide in early primary biliary cirrhosis.

Published in:

Liver International, 2006, v. 26, n. 3, p. 285, doi. 10.1111/j.1478-3231.2005.01222.x

By:

Dilger, Karin;
Cascorbi, Ingolf;
Grünhage, Frank;
Hohenester, Simon;
Sauerbruch, Tilman;
Beuers, Ulrich

Publication type:

Article

Bile duct proliferation associated with bile salt-induced hypercholeresis in Mdr2 P-glycoprotein-deficient mice.

Published in:

Liver International, 2005, v. 25, n. 3, p. 604, doi. 10.1111/j.1478-3231.2005.01036.x

By:

Hulzebos, Christian V.;
Voshol, Peter J.;
Wolters, Henk;
Kruit, Janine K.;
Ottenhof, Roelof;
Groen, Albert K.;
Stellaard, Frans;
Verkade, Henkjan J.;
Kuipers, Folkert

Publication type:

Article

Controllable Generation of Nitric Oxide by Near-Infrared-Sensitized Upconversion Nanoparticles for Tumor Therapy.

Published in:

Advanced Functional Materials, 2015, v. 25, n. 20, p. 3049, doi. 10.1002/adfm.201404402

By:

Zhang, Xiao;
Tian, Gan;
Yin, Wenyan;
Wang, Liming;
Zheng, Xiaopeng;
Yan, Liang;
Li, Jinxia;
Su, Haoran;
Chen, Chunying;
Gu, Zhanjun;
Zhao, Yuliang

Publication type:

Article

Virulence Factors and Azole-Resistant Mechanism of Candida Tropicalis Isolated from Candidemia.

Published in:

Mycopathologia, 2021, v. 186, n. 6, p. 847, doi. 10.1007/s11046-021-00580-y

By:

Sasani, Elahe;
Yadegari, Mohammad Hossein;
Khodavaisy, Sadegh;
Rezaie, Sassan;
Salehi, Mohammadreza;
Getso, Muhammad Ibrahim

Publication type:

Article

Temozolomide reverses doxorubicin resistance by inhibiting P-glycoprotein in malignant glioma cells.

Published in:

Journal of Neuro-Oncology, 2016, v. 126, n. 2, p. 235, doi. 10.1007/s11060-015-1968-x

By:

Zhang, Rong;
Saito, Ryuta;
Shibahara, Ichiyo;
Sugiyama, Shinichiro;
Kanamori, Masayuki;
Sonoda, Yukihiko;
Tominaga, Teiji

Publication type:

Article

EGCG inhibits properties of glioma stem-like cells and synergizes with temozolomide through downregulation of P-glycoprotein inhibition.

Published in:

Journal of Neuro-Oncology, 2015, v. 121, n. 1, p. 41, doi. 10.1007/s11060-014-1604-1

By:

Zhang, Yong;
Wang, Shao-Xiang;
Ma, Ji-Wei;
Li, Hai-Ying;
Ye, Jie-Cheng;
Xie, Si-Ming;
Du, Bin;
Zhong, Xue-Yun

Publication type:

Article

Examination of blood-brain barrier (BBB) integrity in a mouse brain tumor model.

Published in:

Journal of Neuro-Oncology, 2013, v. 111, n. 2, p. 133, doi. 10.1007/s11060-012-1006-1

By:

On, Ngoc;
Mitchell, Ryan;
Savant, Sanjot;
Bachmeier, Corbin.;
Hatch, Grant;
Miller, Donald

Publication type:

Article

Multidrug resistance proteins expression in glioma patients with epilepsy.

Published in:

Journal of Neuro-Oncology, 2012, v. 110, n. 1, p. 129, doi. 10.1007/s11060-012-0946-9

By:

Calatozzolo, Chiara;
Pollo, Bianca;
Botturi, Andrea;
Dinapoli, Loredana;
Carosi, Mariantonia;
Salmaggi, Andrea;
Maschio, Marta

Publication type:

Article

Inflammation alters the expression pattern of drug transporters during Caco‐2 cell stimulation and azoxymethane‐induced colon tumorigenesis.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 9, p. 1, doi. 10.1002/jbt.23815

By:

El‐Daly, Sherien M.;
Gouhar, Shaimaa A.;
Abdelrahman, Sahar S.

Publication type:

Article

NOD2 silencing promotes cell apoptosis and inhibits drug resistance in chronic lymphocytic leukemia by inhibiting the NF‐κB signaling pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 12, p. 1, doi. 10.1002/jbt.23510

By:

Zheng, Cuiping;
Zhu, Zongsi;
Weng, Shanshan;
Zhang, Qikai;
Fu, Yixiao;
Cai, Xiaoping;
Liu, Zhen;
Shi, Yuejian

Publication type:

Article

Reversal of P‐glycoprotein‐mediated multidrug resistance by natural N‐alkylated indole alkaloid derivatives in KB‐ChR‐8‐5 drug‐resistant cancer cells.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 9, p. 1, doi. 10.1002/jbt.23421

By:

Bharathiraja, Pradhapsingh;
Cardoso, David S. P.;
Rajendra Prasad, N.;
Mulhovo, Silva;
Lakra, Deepa S.;
Ferreira, Maria‐José U.

Publication type:

Article

Loperamide potentiates doxorubicin sensitivity in triple‐negative breast cancer cells by targeting MDR1 and JNK and suppressing mTOR and Bcl‐2: In vitro and molecular docking study.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 1, p. 1, doi. 10.1002/jbt.22938

By:

Elia, Shenouda G.;
Al‐Karmalawy, Ahmed A.;
Nasr, Mohamed Y.;
Elshal, Mohamed F.

Publication type:

Article

Arbutin exerts anticancer activity against rat C6 glioma cells by inducing apoptosis and inhibiting the inflammatory markers and P13/Akt/mTOR cascade.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 9, p. 1, doi. 10.1002/jbt.22857

By:

Yang, Zhangkai;
Shi, Hangyu;
Chinnathambi, Arunachalam;
Salmen, Saleh H.;
Alharbi, Sulaiman A.;
Veeraraghavan, Vishnu Priya;
Surapaneni, Krishna Mohan;
Arulselvan, Palanisamy

Publication type:

Article

KLF5 influences cell biological function and chemotherapy sensitivity through the JNK signaling pathway in anaplastic thyroid carcinoma.

Published in:

Journal of Biochemical & Molecular Toxicology, 2020, v. 34, n. 5, p. 1, doi. 10.1002/jbt.22469

By:

Wang, Zheng;
Qiu, Xinguang;
Zhang, Hao;
Li, Weihan

Publication type:

Article

Clinical relevance of P-glycoprotein activity on peripheral blood mononuclear cells and polymorphonuclear neutrophils to methotrexate in systemic lupus erythematosus patients.

Published in:

Clinical Rheumatology, 2017, v. 36, n. 10, p. 2267, doi. 10.1007/s10067-017-3728-0

By:

García-Carrasco, Mario;
Mendoza-Pinto, Claudia;
Macías-Díaz, Salvador;
Etchegaray-Morales, Ivet;
Méndez-Martínez, Socorro;
Soto-Santillán, Pamela;
Pérez-Romano, Beatriz;
Jiménez-Herrera, Erick;
Guzmán-Ruiz, Omar;
Ruiz-Argüelles, Alejandro

Publication type:

Article

Synthesis of the Multidrug Reversal Agent Ko143 and Its Parent Natural Product Fumitremorgin C.

Published in:

Helvetica Chimica Acta, 2023, v. 106, n. 2, p. 1, doi. 10.1002/hlca.202200171

By:

Zechner, Melanie;
Altmann, Karl‐Heinz

Publication type:

Article

A new method to measure intestinal activity of P-glycoprotein in avian and mammalian species.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2005, v. 175, n. 1, p. 57, doi. 10.1007/s00360-004-0462-0

By:

Green, Adam K.;
Barnes, David M.;
Karasov, William H.

Publication type:

Article

P-glycoprotein-like protein contributes to cadmium resistance in Euglena gracilis.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2003, v. 173, n. 7, p. 559, doi. 10.1007/s00360-003-0365-5

By:

Einicker-Lamas, M.;
Morales, M. M.;
Miranda, K.;
Garcia-Abreu, J.;
Oliveira, A. J. F.;
Silva, F. L. S.;
Oliveira, M. M.

Publication type:

Article

Post-mortem ABCB1 genotyping reveals an elevated toxicity for female digoxin users.

Published in:

International Journal of Legal Medicine, 2011, v. 125, n. 2, p. 265, doi. 10.1007/s00414-011-0550-0

By:

Neuvonen, Anu M.;
Palo, Jukka U.;
Sajantila, Antti

Publication type:

Article

Overexpression of the ABC transporter AvtAB increases avermectin production in Streptomyces avermitilis.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 92, n. 2, p. 337, doi. 10.1007/s00253-011-3439-4

By:

Qiu, Jingfan;
Zhuo, Ying;
Zhu, Dongqing;
Zhou, Xiufen;
Zhang, Lixin;
Bai, Linquan;
Deng, Zixin

Publication type:

Article

Effects of Patupilone (Epothilone B; EPO906), a Novel Chemotherapeutic Agent, in Hepatocellular Carcinoma: An in vitro Study.

Published in:

Oncology, 2006, v. 71, n. 3/4, p. 292, doi. 10.1159/000106450

By:

Mok, Tony S. K.;
Choi, Eve;
Yau, Daisy;
Johri, Anandhi;
Yeo, Winnie;
Chan, Anthony T. C.;
Wong, Cesar

Publication type:

Article

Determination and Prediction of P-Glycoprotein and Multidrug-Resistance-Related Protein Expression in Breast Cancer with Double-Phase Technetium-99m Sestamibi Scintimammography.

Published in:

Oncology, 2006, v. 70, n. 6, p. 403, doi. 10.1159/000098812

By:

In-Ju Kim;
Young-Tae Bae;
Seong-Jang Kim;
Yong-Ki Kim;
Dong-Soo Kim;
Jung Sub Lee

Publication type:

Article

Analysis of P-gp genes relative expression associated to ivermectin resistance in Haemonchus contortus larval stages from in vitro cultures (L3 and xL3) and from gerbils (Meriones unguiculatus) (L4) as models of study.

Published in:: Journal of Helminthology, 2024, v. 98, p. 1, doi. 10.1017/S0022149X24000087
Publication type:: Article

P-glycoproteins of Haemonchus contortus: development of real-time PCR assays for gene expression studies.

Published in:

Journal of Helminthology, 2012, v. 86, n. 2, p. 202, doi. 10.1017/S0022149X11000216

By:

Williamson, S.M.;
Wolstenholme, A.J.

Publication type:

Article

Comparison of α2,6-sialyltransferases for sialylation of therapeutic proteins.

Published in:

Glycobiology, 2019, v. 29, n. 10, p. 735, doi. 10.1093/glycob/cwz050

By:

Janesch, Bettina;
Saxena, Hirak;
Sim, Lyann;
Wakarchuk, Warren W

Publication type:

Article

Algal products as naturally occurring substrates for p-glycoprotein in Mytilus californianus.

Published in:

Marine Biology, 2002, v. 140, n. 2, p. 343, doi. 10.1007/s002270100693

By:

Eufemia, N.;
Clerte, S.;
Girshick, S.;
Epel, D.

Publication type:

Article

Analysis of ABCC3 in glioma progression: implications for prognosis, immunotherapy, and drug resistance.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01895-8

By:

Shen, Liang;
Shen, Haitao;
Wang, Tong;
Chen, Gang;
Yu, Zhengquan;
Liu, Fang

Publication type:

Article

Augumented bioavailability of maltodextrin-based Tenofovir proniosomes via inhibition of MDR1 mediated transport efflux.

Published in:

Journal of Research in Pharmacy, 2024, v. 28, n. 5, p. 1357, doi. 10.29228/jrp.814

By:

ARVAPALLI, Swarupa;
ARETI, Anka Rao

Publication type:

Article

The involvement of miRNAs in CYP450 gene expression: A brief review of the literature.

Published in:

Journal of Research in Pharmacy, 2022, v. 26, n. 2, p. 243, doi. 10.29228/jrp.122

By:

TEZCAN, Tuğba;
ÖZKAN-KOTİLOĞLU, Selin;
KAYA-AKYÜZLÜ, Dilek

Publication type:

Article

Attenuation of intestinal efflux pump thru polymers and preservatives.

Published in:

Journal of Research in Pharmacy, 2019, v. 23, n. 4, p. 632, doi. 10.12991/jrp.2019.171

By:

MOHAMMADZADEH, Ramin;
BARADARAN, Behzad;
YOUSEFI, Bahman;
VALIZADEH, Hadi;
ZAKERI-MILANI, Parvin

Publication type:

Article

Szelénvegyületek, mint új rákellenes szerek rezisztens emlőrák ellen és antibakteriális szerek Chlamydia trachomatis D ellen.

Published in:

Magyar Nőorvosok Lapja, 2023, v. 86, n. 2, p. 103

By:

Andrea, Csonka;
Gabriella, Spengler

Publication type:

Article

Time- and passage-dependent characteristics of a Calu-3 respiratory epithelial cell model.

Published in:

Drug Development & Industrial Pharmacy, 2010, v. 36, n. 10, p. 1207, doi. 10.3109/03639041003695113

By:

Haghi, Mehra;
Young, Paul M.;
Traini, Daniela;
Jaiswal, Ritu;
Gong, Joyce;
Bebawy, Mary

Publication type:

Article

The absorption characteristics of bifendate solid dispersion in rat intestinal tissue.

Published in:

Drug Development & Industrial Pharmacy, 2010, v. 36, n. 3, p. 283, doi. 10.3109/03639040903140571

By:

Cheng, Juan;
Wu, Zheng Hong;
Ping, Qineng Neng;
Wang, Bogang;
Lu, Junjun

Publication type:

Article

Does P-Glycoprotein Play a Role in Gastrointestinal Absorption and Cellular Transport of Dietary Cholesterol?.

Published in:

Drug Development & Industrial Pharmacy, 2006, v. 32, n. 6, p. 779, doi. 10.1080/03639040600559073

By:

Leon, C.;
Sachs-Barrable, K.;
Wasan, K. M.

Publication type:

Article

Potential Mechanisms by Which Peceol® Increases the Gastrointestinal Absorption of Amphotericin B.

Published in:

Drug Development & Industrial Pharmacy, 2004, v. 30, n. 7, p. 767, doi. 10.1081/DDC-120039793

By:

Risovic, Verica;
Sachs‐Barrable, Kristina;
Boyd, Michael;
Wasan, Kishor M.

Publication type:

Article

Influence of P-glycoprotein on embryotoxicity of the antifouling biocides to sea urchin ( Strongylocentrotus intermedius).

Published in:

Ecotoxicology, 2011, v. 20, n. 2, p. 419, doi. 10.1007/s10646-011-0593-5

By:

Xue Xu;
Jingxuan Fu;
Heng Wang;
Baidong Zhang;
Xia Wang;
Yonghua Wang

Publication type:

Article

ABCB1 confers resistance to carboplatin by accumulating stem-like cells in the G2/M phase of the cell cycle in p53<sup>null</sup> ovarian cancer.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02435-7

By:

Lee, Danbi;
Jeong, Hyun-Seok;
Hwang, Sun-Young;
Lee, Yu-Gyeong;
Kang, Youn-Jung

Publication type:

Article

The Differentiation and Regeneration Potential of ABCB5 + Mesenchymal Stem Cells: A Review and Clinical Perspectives.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 3, p. 660, doi. 10.3390/jcm14030660

By:

He, Zheng;
Starkuviene, Vytaute;
Keese, Michael

Publication type:

Article

Role of CES1 and ABCB1 Genetic Polymorphisms on Functional Response to Dabigatran in Patients with Atrial Fibrillation.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 9, p. 2545, doi. 10.3390/jcm13092545

By:

Cumitini, Luca;
Renda, Giulia;
Giordano, Mara;
Rolla, Roberta;
Shail, Tarek;
Sacchetti, Sara;
Iezzi, Lorena;
Giacomini, Luca;
Zanotti, Valentina;
Auciello, Raffaella;
Angilletta, Ilaria;
Foglietta, Melissa;
Zucchelli, Mirco;
Antonucci, Ivana;
Stuppia, Liborio;
Gallina, Sabina;
Dianzani, Umberto;
Patti, Giuseppe

Publication type:

Article

Possible New Histological Prognostic Index for Large B-Cell Lymphoma.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 19, p. 6324, doi. 10.3390/jcm12196324

By:

Nitta, Hideaki;
Takizawa, Haruko;
Mitsumori, Toru;
Iizuka-Honma, Hiroko;
Araki, Yoshihiko;
Fujishiro, Maki;
Tomita, Shigeki;
Kishikawa, Satsuki;
Hashizume, Akane;
Sawada, Tomohiro;
Okubo, Mitsuo;
Sekiguchi, Yasunobu;
Ando, Miki;
Noguchi, Masaaki

Publication type:

Article

ABCB1 Is Frequently Methylated in Higher-Grade Gliomas and May Serve as a Diagnostic Biomarker of More Aggressive Tumors.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 19, p. 5655, doi. 10.3390/jcm11195655

By:

Majchrzak-Celińska, Aleksandra;
Sidhu, Arvinder;
Miechowicz, Izabela;
Nowak, Witold;
Barciszewska, Anna-Maria

Publication type:

Article

The Relationship of ABCB1/MDR1 and CYP1A1 Variants with the Risk of Disease Development and Shortening of Overall Survival in Patients with Multiple Myeloma.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 22, p. 5276, doi. 10.3390/jcm10225276

By:

Zmorzynski, Szymon;
Wojcierowska-Litwin, Magdalena;
Popek-Marciniec, Sylwia;
Szudy-Szczyrek, Aneta;
Styk, Wojciech;
Chocholska, Sylwia;
Filip, Agata Anna

Publication type:

Article