Works about NUCLEOPHILIC substitution reactions

Results: 827

Synthesis, cytotoxic screening and molecular docking, DFT calculation of novel furan-heterocyclic derivatives as insecticidal agents.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-06248-7

By:

El-kasabi, Hager G.;
Girges, Margret M.;
El-Salam, Samira A. Abd;
Suliman, Ahmed E.;
Abdel-Ghani, Ghada E.

Publication type:

Article

Synthesis, Biological Evaluation, Molecular Dynamics, and QM-MM Calculation of Spiro-Acridine Derivatives Against Leishmaniasis.

Published in:

Microorganisms, 2025, v. 13, n. 6, p. 1297, doi. 10.3390/microorganisms13061297

By:

Albino, Sonaly;
Nobre, Michelangela;
da Silva, Jamire;
Reis, Malu dos;
Nascimento, Maria;
de Oliveira, Mayara;
Borges, Tatiana;
Albuquerque, Lucas;
Kuckelhaus, Selma;
Alves, Luis;
dos Santos, Fábio;
de Lima, Maria;
Nascimento, Igor;
da Silva, Teresinha;
de Moura, Ricardo

Publication type:

Article

A simple method of simultaneously endowing paper or fluff pulp with both high softness or appropriate fluffing properties and antimicrobial properties.

Published in:

Cellulose, 2021, v. 28, n. 11, p. 7327, doi. 10.1007/s10570-021-04025-z

By:

Xu, Yongjian;
Shi, Yun;
Chen, Xuyong;
Liu, Fenfen;
Zhao, Wei

Publication type:

Article

Design and development of novel N‐(4‐aminobenzoyl)‐ l‐glutamic acid conjugated 1,3,5‐triazine derivatives as Pf‐DHFR inhibitor: An in‐silico and in‐vitro study.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 4, p. 1, doi. 10.1002/jbt.23290

By:

Adhikari, Nayana;
Choudhury, Ayesha A. K.;
Shakya, Anshul;
Ghosh, Surajit K.;
Patgiri, Saurav J.;
Singh, Udaya P.;
Bhat, Hans R.

Publication type:

Article

Synthesis and Reactions of Trifluoromethyl‐Substituted 1,3,5‐Triazines.

Published in:

Helvetica Chimica Acta, 2023, v. 106, n. 9, p. 1, doi. 10.1002/hlca.202300091

By:

Jeon, Woohyung;
Baiazitov, Ramil;
Chierchia, Matteo;
Niederer, Kyle;
Ren, Hongyu;
Moon, Young‐Choon;
Gilbert, Bradley B.

Publication type:

Article

A Journey through Hemetsberger–Knittel, Leimgruber–Batcho and Bartoli Reactions: Access to Several Hydroxy 5‐ and 6‐Azaindoles.

Published in:

Helvetica Chimica Acta, 2022, v. 105, n. 3, p. 1, doi. 10.1002/hlca.202100211

By:

Radix, Sylvie;
Hallé, François;
Mahiout, Zahia;
Teissonnière, Amélie;
Bouchez, Grégoire;
Auberger, Ludovic;
Barret, Roland;
Lomberget, Thierry

Publication type:

Article

Computational Study of Benzosultam Formation through Gold(I)‐Catalyzed Ammoniumation/Nucleophilic Substitution Reaction.

Published in:

Helvetica Chimica Acta, 2021, v. 104, n. 10, p. 1, doi. 10.1002/hlca.202100133

By:

Pertschi, Romain;
de Aguirre, Adiran;
Pale, Patrick;
Blanc, Aurélien;
Poblador Bahamonde, Amalia I.

Publication type:

Article

A Metal-Free Synthesis of 2-Alkyl(or Aryl) Thiomethyl-2-cyclohexenones from Cyclic Morita- Baylis- Hillman Bromides.

Published in:

Helvetica Chimica Acta, 2016, v. 99, n. 9, p. 704, doi. 10.1002/hlca.201600136

By:

Baioui, Narjes;
Abidi, Ahlem;
Rezgui, Farhat

Publication type:

Article

Investigation of the Acid/Basic Sites of Zeolite Trough Some Catalysed Nucleophilic Reactions.

Published in:

Foundations (2673-9321), 2023, v. 3, n. 1, p. 72, doi. 10.3390/foundations3010008

By:

Verdoliva, Valentina;
Saviano, Michele;
De Luca, Stefania

Publication type:

Article

Synthesis and Activity Test of 1-Allyl-3-(4-tertiary-Butylbenzoyl) Thioureaas a Candidate of an Analgesic Drug.

Published in:

Pharmacy & Pharmaceutical Sciences Journal / Jurnal Farmasi Dan Ilmu Kefarmasian Indonesia, 2022, v. 9, n. 1, p. 17, doi. 10.20473/jfiki.v9i12022.17-23

By:

Razak, Rais;
Siswandono;
Ekowati, Juni

Publication type:

Article

Theoretical Studies on OH−+NH2Cl Reaction: Nucleophilic Substitution at Neutral Nitrogen.

Published in:

Journal of Computational Biophysics & Chemistry, 2023, v. 22, n. 2, p. 175, doi. 10.1142/S2737416523500102

By:

Li, Rui;
Liu, Xu;
Pang, Boxue;
Li, Hui;
Wu, Yang

Publication type:

Article

Urea Delays High-Temperature Crosslinking of Polyacrylamide for In Situ Preparation of an Organic/Inorganic Composite Gel.

Published in:

Gels (2310-2861), 2025, v. 11, n. 4, p. 256, doi. 10.3390/gels11040256

By:

Liang, Li;
Li, Junlong;
Li, Dongxiang;
Xu, Jie;
Zheng, Bin;
Zhao, Jikuan

Publication type:

Article

SYNTHESIS OF SOME DERIVATIVES OF 2,3-TETRAMETHYLENE-3,4-DIHYDROQUINAZOLIN-4-ONE AND -THIONE.

Published in:

Austrian Journal of Technical & Natural Sciences, 2024, n. 9/10, p. 43, doi. 10.29013/AJT-24-9.10-43-48

By:

Ozodovich, Nasrullaev Azizbek;
Davlat, Tukhtaev;
Akbarovich, Samiev Rajab;
Iskandarzoda, Kodirov Khakim;
Ilyasbek, Karimov;
Akilovich, Zohidov Kasim;
Ergashevich, Saitkulov Foziljon

Publication type:

Article

Hyper-crosslinked 4-amino-1,8-naphthalimide Tröger's base containing pyridinium covalent organic polymer (COP) for discriminative fluorescent sensing of chemical explosives.

Published in:

Supramolecular Chemistry, 2020, v. 32, n. 9, p. 508, doi. 10.1080/10610278.2020.1825715

By:

Delente, Jason M.;
Umadevi, Deivasigamani;
Byrne, Kevin;
Schmitt, Wolfgang;
Watson, Graeme W.;
Gunnlaugsson, Thorfinnur;
Shanmugaraju, Sankarasekaran

Publication type:

Article

Synthesis and Detonation Properties of 5-Amino-2,4,6-trinitro-1,3-dihydroxy-benzene.

Published in:

ChemistryOpen, 2017, v. 6, n. 3, p. 447, doi. 10.1002/open.201600132

By:

Zhang, XingchENg;
Xiong, Hualin;
Yang, Hongwei;
ChENg, Guangbin

Publication type:

Article

Cross-linking of PVC by Various Lengths of PEG via "Click" Chemistry.

Published in:

Karaelmas Science & Engineering Journal / Karaelmas Fen ve Mühendislik Dergisi, 2022, v. 12, n. 1, p. 59, doi. 10.7212/karaelmasfen.992843

By:

Asan, Nilgün;
Öztürk, Temel;
Kudu, Hasibe;
Meyvacı, Ergül;
Çatıker, Efkan

Publication type:

Article

4‐triphenylmethylaniline substituted cyclotriphosphazene derivatives assisted by multiple phenyl rings.

Published in:

Journal of the Chinese Chemical Society, 2022, v. 69, n. 5, p. 812, doi. 10.1002/jccs.202200046

By:

Mutlu Balcı, Ceylan;
Palabıyık, Duygu

Publication type:

Article

A Convenient Synthetic Method and Spectral Characterization of New Tetrahydro[1,3]oxazinothieno[2,3- c]isoquinoline and Its Pyrimidine Derivatives.

Published in:

Journal of the Chinese Chemical Society, 2017, v. 64, n. 12, p. 1417, doi. 10.1002/jccs.201700232

By:

Zaki, Remon M.;
Radwan, Shaban M.;
Kamal El-Dean, Adel M.

Publication type:

Article

Structural Features of Certain p-substituted Phenyl 2-nitrovinyl Sulfones.

Published in:

Journal of the Chinese Chemical Society, 2016, v. 63, n. 3, p. 247, doi. 10.1002/jccs.201500408

By:

Zvezdova, Dilyana;
Stoeva, Stoyanka;
Aleksiev, Dimitar

Publication type:

Article

Molecular docking and antimalarial evaluation of novel N-(4-aminobenzoyl)-l-glutamic acid conjugated 1,3,5-triazine derivatives as Pf-DHFR inhibitors.

Published in:

3 Biotech, 2022, v. 12, n. 12, p. 1, doi. 10.1007/s13205-022-03400-2

By:

Adhikari, Nayana;
Choudhury, Ayesha Aktar Khanam;
Shakya, Anshul;
Ghosh, Surajit Kumar;
Patgiri, Saurav Jyoti;
Singh, Udaya Pratap;
Bhat, Hans Raj

Publication type:

Article

Phase-transfer-catalyst enabled enantioselective C–N coupling to access chiral boron-stereogenic BODIPYs.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-58117-6

By:

Zhang, Xue-Qing;
Lv, Xiao-Juan;
Guo, Luying;
Ma, Juan;
Su, Bin;
Hu, Yuefei;
Jiao, Lijuan;
Li, Zhong-Yuan;
Hao, Erhong

Publication type:

Article

A dynamic isotope effect in the nucleophilic substitution reaction between F− and CD3I.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-57086-0

By:

Ayasli, Atilay;
Khan, Arnab;
Gstir, Thomas;
Michaelsen, Tim;
Papp, Dóra;
Wang, Yan;
Song, Hongwei;
Yang, Minghui;
Czakó, Gábor;
Wester, Roland

Publication type:

Article

The Influence of Structural Patterns on Acute Aquatic Toxicity of Organic Compounds.

Published in:

Molecular Informatics, 2021, v. 40, n. 9, p. 1, doi. 10.1002/minf.202000209

By:

Tinkov, Oleg;
Polishchuk, Pavel;
Matveieva, Mariia;
Grigorev, Veniamin;
Grigoreva, Ludmila;
Porozov, Yuri

Publication type:

Article

Bimolecular Nucleophilic Substitution Reactions: Predictive Models for Rate Constants and Molecular Reaction Pairs Analysis.

Published in:

Molecular Informatics, 2019, v. 38, n. 4, p. N.PAG, doi. 10.1002/minf.201800104

By:

Gimadiev, Timur;
Madzhidov, Timur;
Tetko, Igor;
Nugmanov, Ramil;
Casciuc, Iury;
Klimchuk, Olga;
Bodrov, Andrey;
Polishchuk, Pavel;
Antipin, Igor;
Varnek, Alexandre

Publication type:

Article

Design and synthesis of ladder-type covalent organic frameworks.

Published in:

Arabian Journal of Chemistry, 2024, v. 17, n. 10, p. N.PAG, doi. 10.1016/j.arabjc.2024.105987

By:

Sun, Hongfei;
Wu, Xianying;
Yao, Bin;
Li, Guowang;
Qi, Ning;
Shi, Lei

Publication type:

Article

Computer-aided molecular design of solvents for accelerated reaction kinetics.

Published in:

Nature Chemistry, 2013, v. 5, n. 11, p. 952, doi. 10.1038/nchem.1755

By:

Struebing, Heiko;
Ganase, Zara;
Karamertzanis, Panagiotis G.;
Siougkrou, Eirini;
Haycock, Peter;
Piccione, Patrick M.;
Armstrong, Alan;
Galindo, Amparo;
Adjiman, Claire S.

Publication type:

Article

Mechanochemical strengthening of a synthetic polymer in response to typically destructive shear forces.

Published in:

Nature Chemistry, 2013, v. 5, n. 9, p. 757, doi. 10.1038/nchem.1720

By:

Ramirez, Ashley L. Black;
Kean, Zachary S.;
Orlicki, Joshua A.;
Champhekar, Mangesh;
Elsakr, Sarah M.;
Krause, Wendy E.;
Craig, Stephen L.

Publication type:

Article

Reaction mechanisms: Stripping down SN2.

Published in:

Nature Chemistry, 2012, v. 4, n. 7, p. 522, doi. 10.1038/nchem.1377

By:

Orr-Ewing, Andrew J.

Publication type:

Article

First 'Click' Synthesis of the Ribbed-Functionalized Metal Clathrochelates: Cycloaddition of Benzyl Azide to Propargylamine Iron(II) Macrobicycle and the Unexpected Transformations of the Resulting Cage Complex.

Published in:

European Journal of Inorganic Chemistry, 2012, v. 2012, n. 28, p. 4507, doi. 10.1002/ejic.201200628

By:

Belov, Alexander S.;
Prikhod'ko, Alexander I.;
Novikov, Valentin V.;
Vologzhanina, Anna V.;
Bubnov, Yurii N.;
Voloshin, Yan Z.

Publication type:

Article

Plasma Bromination of Graphene for Covalent Bonding of Organic Molecules.

Published in:

Plasma Chemistry & Plasma Processing, 2014, v. 34, n. 3, p. 621, doi. 10.1007/s11090-013-9509-x

By:

Friedrich, Jörg;
Hidde, Gundula;
Lippitz, Andreas;
Unger, Wolfgang

Publication type:

Article

The Truce-Smiles rearrangement and related reactions: a review.

Published in:

Canadian Journal of Chemistry, 2017, v. 95, n. 5, p. 483, doi. 10.1139/cjc-2016-0594

By:

Henderson, Anna R.P.;
Kosowan, Joel R.;
Wood, Tabitha E.

Publication type:

Article

Gas-phase reaction of ClO− with CH nCl4- n ( n = 0, 1, 2, 3) and CX3H (X = F, Cl and Br): Substituent effect from a comparative study.

Published in:

Canadian Journal of Chemistry, 2014, v. 92, n. 9, p. 868, doi. 10.1139/cjc-2014-0245

By:

Junxi, Liang;
Qiong, Su;
Yu, Li;
Qiang, Zhang;
Zhiyuan, Geng

Publication type:

Article

Direct benzylation of 1,3-dicarbonyl compounds catalyzed by Cs2.5H0.5PW12O40 in solvent-free conditions.

Published in:

Canadian Journal of Chemistry, 2011, v. 89, n. 12, p. 1533, doi. 10.1139/v11-134

By:

Rafiee, Ezzat;
Khodayari, Maryam;
Joshaghani, Mohammad

Publication type:

Article

Photoinduced C-C Cross-Coupling of Aryl Chlorides and Inert Arenes.

Published in:

International Journal of Photoenergy, 2016, p. 1, doi. 10.1155/2016/5632613

By:

Wang, Lele;
Qiu, Wenzhao;
Shao, Hongge;
Yuan, Rusheng

Publication type:

Article

Click and Multicomponent Reactions Work Together for Polymer Chemistry.

Published in:

Macromolecular Chemistry & Physics, 2018, v. 219, n. 16, p. 1, doi. 10.1002/macp.201800163

By:

Tunca, Umit

Publication type:

Article

Highly Efficient Chain End Derivatization of Selenol-Ended Polystyrenes by Nucleophilic Substitution Reactions.

Published in:

Macromolecular Chemistry & Physics, 2017, v. 218, n. 4, p. n/a, doi. 10.1002/macp.201600485

By:

Lu, Weihong;
An, Xiaowei;
Gao, Feng;
Zhu, Jian;
Zhou, Nianchen;
Zhang, Zhengbiao;
Pan, Xiangqiang;
Zhu, Xiulin

Publication type:

Article

Selenium Nucleophilicity and Electrophilicity in the Intra‐ and Intermolecular SN2 Reactions of Selenenyl Sulfide Probes.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 12, p. 1, doi. 10.1002/chem.202404580

By:

Madabeni, Andrea;
Zeisel, Lukas;
Thorn‐Seshold, Oliver;
Orian, Laura

Publication type:

Article

A Study on Auto‐Catalysis and Product Inhibition: A Nucleophilic Aromatic Substitution Reaction Catalysed within the Cavity of an Octanuclear Coordination Cage.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 27, p. 1, doi. 10.1002/chem.202400501

By:

Dorrat, Jack C.;
Taylor, Christopher G. P.;
Young, Rosemary J.;
Solea, Atena B.;
Turner, David R.;
Dennison, Genevieve H.;
Ward, Michael D.;
Tuck, Kellie L.

Publication type:

Article

Backside versus Frontside SN2 Reactions of Alkyl Triflates and Alcohols.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 25, p. 1, doi. 10.1002/chem.202400590

By:

Remmerswaal, Wouter A.;
de Jong, Tjeerd;
van de Vrande, Koen N. A.;
Louwersheimer, Rick;
Verwaal, Thomas;
Filippov, Dmitri V.;
Codée, Jeroen D. C.;
Hansen, Thomas

Publication type:

Article

Nucleophilic Substitution at Phosphorus Centres – Old and Recent Studies and a Final Solution of Mechanistic and Related Stereochemical Problems.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 16, p. 1, doi. 10.1002/chem.202302974

By:

Mikołajczyk, Marian

Publication type:

Article

Synthesis of Hypervalent Iodine Diazo Compounds and Their Application in Organic Synthesis.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 5, p. 1, doi. 10.1002/chem.202302718

By:

Zhang, Cai;
Wan, Jie‐Ping

Publication type:

Article

Neighboring‐Group Participation by C‐2 Acyloxy Groups: Influence of the Nucleophile and Acyl Group on the Stereochemical Outcome of Acetal Substitution Reactions.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 57, p. 1, doi. 10.1002/chem.202301894

By:

Chun, Yuge;
Remmerswaal, Wouter A.;
Codée, Jeroen D. C.;
Woerpel, K. A.

Publication type:

Article

Induction and Stabilization of Columnar Mesophases in Fluorinated Polycyclic Aromatic Hydrocarbons by Arene‐Perfluoroarene Interactions.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 56, p. 1, doi. 10.1002/chem.202301829

By:

Zhou, Ming‐Mei;
He, Jiao;
Pan, Hui‐Min;
Zeng, Qing;
Lin, Hang;
Zhao, Ke‐Qing;
Hu, Ping;
Wang, Bi‐Qin;
Donnio, Bertrand

Publication type:

Article

Diverse Synthesis of 2H‐Isoindole‐Based Polycyclic Aromatic Compounds.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 50, p. 1, doi. 10.1002/chem.202301703

By:

Kawazoe, Teru;
Yanai, Hikaru;
Hagiyama, Yuto;
Funabiki, Kazumasa;
Matsumoto, Takashi

Publication type:

Article

Red‐to‐Near‐Infrared Emitting PyrrolylBODIPY Dyes: Synthesis, Photophysical Properties and Bioimaging Application.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 14, p. 1, doi. 10.1002/chem.202203832

By:

Miao, Wei;
Guo, Xing;
Yan, Xi;
Shang, Yingjian;
Yu, Changjiang;
Dai, En;
Jiang, Ting;
Hao, Erhong;
Jiao, Lijuan

Publication type:

Article

A Cascade Sonogashira Cross‐Coupling‐Substitution‐Elimination Reaction for the Synthesis of Linear Conjugated Dienynes.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 71, p. 1, doi. 10.1002/chem.202202421

By:

Lumbreras‐Teijeiro, Alejandro;
Bacic, Matea;
Oliver‐Meseguer, Judit;
Leyva‐Pérez, Antonio

Publication type:

Article

Synthesis, Reactivity and Structural Properties of Trifluoromethylphosphoranides.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 14, p. 1, doi. 10.1002/chem.202104308

By:

Shyshkov, Oleg O.;
Kolomeitsev, Alexander A.;
Hoge, Berthold;
Lork, Enno;
Haupt, Axel;
Keßler, Mira;
Röschenthaler, Gerd‐Volker

Publication type:

Article

Frontispiece: Perfluoroaryl and Perfluoroheteroaryl Reagents as Emerging New Tools for Peptide Synthesis, Modification and Bioconjugation.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 7, p. 1, doi. 10.1002/chem.202103305

By:

Brittain, William D. G.;
Coxon, Christopher R.

Publication type:

Article

Stable and Storable N(CF3)2 Transfer Reagents.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 42, p. 10973, doi. 10.1002/chem.202101436

By:

Schneider, Leon N.;
Tanzer Krauel, Eva‐Maria;
Deutsch, Carl;
Urbahns, Klaus;
Bischof, Tobias;
Maibom, Kristina A. M.;
Landmann, Johannes;
Keppner, Fabian;
Kerpen, Christoph;
Hailmann, Michael;
Zapf, Ludwig;
Knuplez, Tanja;
Bertermann, Rüdiger;
Ignat'ev, Nikolai V.;
Finze, Maik

Publication type:

Article

Interconnectivity between Surface Reactivity and Self‐Assembly of Kemp Elimination Catalyzing Nanorods.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 29, p. 7831, doi. 10.1002/chem.202100450

By:

Shandilya, Ekta;
Dasgupta, Basundhara;
Maiti, Subhabrata

Publication type:

Article