Works about NUCLEASES

Results: 1320

Mechanisms and engineering of a miniature type V-N CRISPR-Cas12 effector enzyme.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61290-3

By:

Fu, Wenhan;
Ma, Jiacheng;
Wang, Zhipeng;
Tang, Na;
Pan, Deng;
Su, Mengjiao;
Wu, Zhaowei;
Gan, Jianhua;
Ji, Quanjiang

Publication type:

Article

Fission Yeast Pxd1 Promotes Proper DNA Repair by Activating Rad16XPF and Inhibiting Dna2.

Published in:

PLoS Biology, 2014, v. 12, n. 9, p. 1, doi. 10.1371/journal.pbio.1001946

By:

Zhang, Jia-Min;
Liu, Xiao-Man;
Ding, Yue-He;
Xiong, Liang-Yao;
Ren, Jing-Yi;
Zhou, Zhi-Xiong;
Wang, Hai-Tao;
Zhang, Mei-Jun;
Yu, Yang;
Dong, Meng-Qiu;
Du, Li-Lin

Publication type:

Article

An Endoribonuclease Functionally Linked to Perinuclear mRNP Quality Control Associates with the Nuclear Pore Complexes.

Published in:

PLoS Biology, 2009, v. 7, n. 1, p. e1000008, doi. 10.1371/journal.pbio.1000008

By:

Skrunžný, Michal;
Schneider, Claudia;
Rácz, Attila;
Weng, Julan;
Tollervey, David;
Hurt, Ed

Publication type:

Article

Darwinian Evolution on a Chip.

Published in:

PLoS Biology, 2008, v. 6, n. 4, p. e85, doi. 10.1371/journal.pbio.0060085

By:

Paegel, Brian M.;
Joyce, Gerald F.

Publication type:

Article

Genetic and genomic analysis of RNases in model cyanobacteria.

Published in:

Photosynthesis Research, 2015, v. 126, n. 1, p. 171, doi. 10.1007/s11120-015-0076-2

By:

Cameron, Jeffrey;
Gordon, Gina;
Pfleger, Brian

Publication type:

Article

Chromatin structure and DNA methylation of the IL-4 gene in human TH2 cells.

Published in:

Chromosome Research, 2009, v. 17, n. 4, p. 485, doi. 10.1007/s10577-009-9040-3

By:

Samantha Santangelo;
David Cousins;
Kostas Triantaphyllopoulos;
Dontcho Staynov

Publication type:

Article

The evolution of CRISPR/Cas9 and their cousins: hope or hype?

Published in:

Biotechnology Letters, 2018, v. 40, n. 3, p. 465, doi. 10.1007/s10529-018-2506-7

By:

Chaudhary, Kulbhushan;
Chattopadhyay, Anirudha;
Pratap, Dharmendra

Publication type:

Article

Development of a bacterial-based negative selection system for rapid screening of active single guide RNAs.

Published in:

Biotechnology Letters, 2017, v. 39, n. 3, p. 351, doi. 10.1007/s10529-016-2259-0

By:

Nie, Yu;
Cong, Peiqing;
Liu, Xiaofeng;
Wang, Min;
Chen, Yaosheng;
He, Zuyong

Publication type:

Article

Effect of siRNA nuclease stability on the in vitro and in vivo kinetics of siRNA-mediated gene silencing.

Published in:

Biotechnology & Bioengineering, 2007, v. 97, n. 4, p. 909, doi. 10.1002/bit.21285

By:

Bartlett, Derek W.;
Davis, Mark E.

Publication type:

Article

Quantifying the functional impact of siRNA nuclease stability.

Published in:: Biotechnology & Bioengineering, 2007, v. 97, n. 4, p. Fmvii, doi. 10.1002/bit.21514
Publication type:: Article

Theoretical distribution of truncation lengths in incremental truncation libraries.

Published in:

Biotechnology & Bioengineering, 2003, v. 82, n. 5, p. 564, doi. 10.1002/bit.10604

By:

Marc Ostermeier

Publication type:

Article

The MOE Modification of RNA: Origins and Widescale Impact on the Oligonucleotide Therapeutics Field.

Published in:

Helvetica Chimica Acta, 2023, v. 106, n. 3, p. 1, doi. 10.1002/hlca.202200169

By:

Hill, Alyssa C.;
Hall, Jonathan

Publication type:

Article

Structure-function relationships of the Mre11 protein in the control of DNA end bridging and processing.

Published in:

Current Genetics, 2019, v. 65, n. 1, p. 11, doi. 10.1007/s00294-018-0861-5

By:

Marsella, Antonio;
Cassani, Corinne;
Casari, Erika;
Tisi, Renata;
Longhese, Maria Pia

Publication type:

Article

Nuclease integrated kinase super assemblies (NiKs) and their role in RNA processing.

Published in:

Current Genetics, 2018, v. 64, n. 1, p. 183, doi. 10.1007/s00294-017-0749-9

By:

Pillon, Monica;
Stanley, Robin

Publication type:

Article

Enhancement of nuclease P1 production by Penicillium citrinum YL104 immobilized on activated carbon filter sponge.

Published in:

Applied Microbiology & Biotechnology, 2015, v. 99, n. 3, p. 1145, doi. 10.1007/s00253-014-6163-z

By:

Zhao, Nan;
Ren, Hengfei;
Li, Zhenjian;
Zhao, Ting;
Shi, Xinchi;
Cheng, Hao;
Zhuang, Wei;
Chen, Yong;
Ying, Hanjie

Publication type:

Article

Anticodon nuclease encoding virus-like elements in yeast.

Published in:

Applied Microbiology & Biotechnology, 2012, v. 96, n. 2, p. 345, doi. 10.1007/s00253-012-4349-9

By:

Satwika, Dhira;
Klassen, Roland;
Meinhardt, Friedhelm

Publication type:

Article

Peptide nucleic acids (PNAs) antisense effect to bacterial growth and their application potentiality in biotechnology.

Published in:

Applied Microbiology & Biotechnology, 2010, v. 86, n. 2, p. 397, doi. 10.1007/s00253-009-2387-8

By:

Hatamoto, Masashi;
Ohashi, Akiyoshi;
Imachi, Hiroyuki

Publication type:

Article

Production and applications of esterases.

Published in:

Applied Microbiology & Biotechnology, 2005, v. 67, n. 2, p. 160, doi. 10.1007/s00253-004-1840-y

By:

Panda, T.;
Gowrishankar, B. S.

Publication type:

Article

Identification of functional elements of the GDP-fucose transporter SLC35C1 using a novel Chinese hamster ovary mutant.

Published in:

Glycobiology, 2012, v. 22, n. 7, p. 897, doi. 10.1093/glycob/cws064

By:

Zhang, Peiqing;
Haryadi, Ryan;
Chan, Kah Fai;
Teo, Gavin;
Goh, John;
Pereira, Natasha Ann;
Feng, Huatao;
Song, Zhiwei

Publication type:

Article

Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice.

Published in:

Nature Immunology, 2004, v. 5, n. 2, p. 224, doi. 10.1038/ni1031

By:

Bardwell, Philip D.;
Woo, Caroline J.;
Wei, Kaichun;
Li, Ziqiang;
Martin, Alberto;
Sack, Stephen Z.;
Parris, Tchaiko;
Edelmann, Winfried;
Scharff, Matthew D.

Publication type:

Article

CRISPR/Cas9技术在作物遗传育种中的应用进展.

Published in:

Journal of Henan Agricultural Sciences, 2021, v. 50, n. 7, p. 1, doi. 10.15933/j.cnki.1004-3268.2021.07.001

By:

焦耀磊;
王春生;
曲预;
升班班;
朱婷婷;
赵贺;
王丕武

Publication type:

Article

Detection of two diatoms using sandwich hybridization integrated with nuclease protection assay (NPA-SH).

Published in:

Hydrobiologia, 2007, v. 575, n. 1, p. 1, doi. 10.1007/s10750-006-0278-x

By:

Zhen, Yu;
Yu, Zhigang;
Cai, Qingsong;
Mi, Tiezhu;
Li, Rongxiu

Publication type:

Article

CRISPR/Cas9 und andere Genome Editing Techniken.

Published in:

Julius-Kühn-Archiv, 2017, n. 457, p. 36, doi. 10.5073/jka.2017.457.006

By:

Hartung, Frank;
Schiemann, Jochen;
Sprink, Thorben

Publication type:

Article

CELL BIOLOGY SYMPOSIUM: Zinc finger nucleases to create custom-designed modifications in the swine (Sus serofa) genome.

Published in:

Journal of Animal Science, 2012, v. 90, n. 4, p. 1111, doi. 10.2527/jas.2011-4546

By:

Whyte, J. J.;
Prather, R. S.

Publication type:

Article

A COST-EFFECTIVENESS ANALYSIS OF rhDNase IN CHILDREN WITH CYSTIC FIBROSIS.

Published in:

International Journal of Technology Assessment in Health Care, 2003, v. 19, n. 1, p. 71, doi. 10.1017/S0266462303000072

By:

Richard Grieve;
Simon Thompson;
Charles Normand;
Ranjan Suri;
Andrew Bush;
Colin Wallis

Publication type:

Article

Phage tRNAs evade tRNA- targeting host defenses through anticodon loop mutations.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.85183

By:

den Berg Baltus A. van der Steen, Daan F. van;
Costa, Ana Rita;
Brouns, Stan JJ

Publication type:

Article

Possible impact of plasma RNase activity on immune dysfunction in juvenile diabetes mellitus.

Published in:

Pediatric Diabetes, 2005, v. 6, n. 3, p. 155, doi. 10.1111/j.1399-543X.2005.00122.x

By:

Kocic, Gordana;
Bjelakovic, Gordana;
Saranac, Ljiljana;
Zivic, Sasa;
Jevtovic, Tatjana;
Sokolovic, Dusan;
Pavlovic, Dusica;
Pavlovic, Radmila;
Kocic, Radivoj

Publication type:

Article

A CYTOCHEMICAL STUDY OF ACID PHOSPHASE AND NUCLEASE ACTIVITY IN THE PLASTID OF CLOSTERIUM ACEROSUM.

Published in:

Journal of Phycology, 1967, v. 3, n. 1, p. 24, doi. 10.1111/j.1529-8817.1967.tb04624.x

By:

Cook, Philip W.

Publication type:

Article

Dual sgRNA-directed gene knockout using CRISPR/Cas9 technology in Caenorhabditis elegans.

Published in:

Scientific Reports, 2014, p. 7581, doi. 10.1038/srep07581

By:

Chen, Xiangyang;
Xu, Fei;
Zhu, Chengming;
Ji, Jiaojiao;
Zhou, Xufei;
Feng, Xuezhu;
Guang, Shouhong

Publication type:

Article

Novel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleases.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep06409

By:

Mock, Ulrike;
Riecken, Kristoffer;
Berdien, Belinda;
Qasim, Waseem;
Chan, Emma;
Cathomen, Toni;
Fehse, Boris

Publication type:

Article

Using RNA-seq and targeted nucleases to identify mechanisms of drug resistance in acute myeloid leukemia.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep06048

By:

Rathe, Susan K.;
Moriarity, Branden S.;
Stoltenberg, Christopher B.;
Kurata, Morito;
Aumann, Natalie K.;
Rahrmann, Eric P.;
Bailey, Natashay J.;
Melrose, Ellen G.;
Beckmann, Dominic A.;
Liska, Chase R.;
Largaespada, David A.

Publication type:

Article

Highly efficient targeted mutagenesis in one-cell mouse embryos mediated by the TALEN and CRISPR/Cas systems.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep05705

By:

Akihiro Yasue;
Silvia Naomi Mitsui;
Takahito Watanabe;
Tetsushi Sakuma;
Seiichi Oyadomari;
Takashi Yamamoto;
Sumihare Noji;
Taro Mito;
Eiji Tanaka

Publication type:

Article

Adenoviral vector delivery of RNA-guided CRISPR/Cas9 nuclease complexes induces targeted mutagenesis in a diverse array of human cells.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep05105

By:

Maggio, Ignazio;
Holkers, Maarten;
Jin Liu;
Janssen, Josephine M.;
Xiaoyu Chen;
Gonçalves, Manuel A. F. V.

Publication type:

Article

Non-integrating gamma-retroviral vectors as a versatile tool for transient zinc-finger nuclease delivery.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep04656

By:

Bobis-Wozowicz, Sylwia;
Galla, Melanie;
Alzubi, Jamal;
Kuehle, Johannes;
Baum, Christopher;
Schambach, Axel;
Cathomen, Toni

Publication type:

Article

A robust TALENs system for highly efficient mammalian genome editing.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep03632

By:

Yuanxi Feng;
Siliang Zhang;
Xin Huang

Publication type:

Article

Repeating pattern of non-RVD variations in DNA-binding modules enhances TALEN activity.

Published in:

Scientific Reports, 2013, p. 1, doi. 10.1038/srep03379

By:

Tetsushi Sakuma;
Hiroshi Ochiai;
Takehito Kaneko;
Tomoji Mashimo;
Daisuke Tokumasu;
Yuto Sakane;
Ken-ichi Suzuki;
Tatsuo Miyamoto;
Naoaki Sakamoto;
Shinya Matsuura;
Takashi Yamamoto

Publication type:

Article

Analysis of Wild Type LbCpf1 Protein, and PAM Recognition Variants, in a Cellular Context.

Published in:

Frontiers in Genetics, 2021, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.571591

By:

Shin, Ujin;
Brondani, Vincent

Publication type:

Article

A Nuclease from Streptococcus mutans Facilitates Biofilm Dispersal and Escape from Killing by Neutrophil Extracellular Traps.

Published in:

Frontiers in Cellular & Infection Microbiology, 2017, v. 7, p. 1, doi. 10.3389/fcimb.2017.00097

By:

Jia Liu;
Luping Sun;
Wei Liu;
Lihong Guo;
Zhaohui Liu;
Xi Wei;
Junqi Ling

Publication type:

Article

A fluorescent aptasensor based on MoSe2 nanosheets and exonuclease III‐assisted signal amplification for sensitive detection of ZEN.

Published in:

Journal of the Chinese Chemical Society, 2025, v. 72, n. 6, p. 712, doi. 10.1002/jccs.70029

By:

Sun, Jiayi;
Suo, Zhiguang;
Ren, Wenjie;
Xu, Yiwei;
Wei, Min;
Jin, Huali;
He, Baoshan;
Zhao, Renyong

Publication type:

Article

Future of breeding by genome editing is in the hands of regulators.

Published in:

GM Crops & Food, 2015, v. 6, n. 4, p. 223, doi. 10.1080/21645698.2015.1134405

By:

Jones, Huw D

Publication type:

Article

Genome editing for crop improvement: Challenges and opportunities.

Published in:

GM Crops & Food, 2015, v. 6, n. 4, p. 183, doi. 10.1080/21645698.2015.1129937

By:

Abdallah, Naglaa A;
Prakash, Channapatna S;
McHughen, Alan G

Publication type:

Article

Sustainability Council of New Zealand Trust v. The Environmental Protection Authority: Gene editing technologies and the law.

Published in:

GM Crops & Food, 2015, v. 6, n. 4, p. 216, doi. 10.1080/21645698.2015.1122859

By:

Kershen, Drew L

Publication type:

Article

Mouse MRE11-RAD50-NBS1 is needed to start and extend meiotic DNA end resection.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-57928-x

By:

Kim, Soonjoung;
Yamada, Shintaro;
Li, Tao;
Canasto-Chibuque, Claudia;
Kim, Jun Hyun;
Marcet-Ortega, Marina;
Xu, Jiaqi;
Eng, Diana Y.;
Feeney, Laura;
Petrini, John H. J.;
Keeney, Scott

Publication type:

Article

Discovery of the widespread site-specific single-stranded nuclease family Ssn.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-57514-1

By:

Chenal, Martin;
Rivera-Millot, Alex;
Harrison, Luke B.;
Khairalla, Ahmed S.;
Nieves, Cecilia;
Bernet, Ève;
Esmaili, Mansoore;
Belkhir, Manel;
Perreault, Jonathan;
Veyrier, Frédéric J.

Publication type:

Article

DNA targeting by compact Cas9d and its resurrected ancestor.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-024-55573-4

By:

Ocampo, Rodrigo Fregoso;
Bravo, Jack P. K.;
Dangerfield, Tyler L.;
Nocedal, Isabel;
Jirde, Samatar A.;
Alexander, Lisa M.;
Thomas, Nicole C.;
Das, Anjali;
Nielson, Sarah;
Johnson, Kenneth A.;
Brown, Christopher T.;
Butterfield, Cristina N.;
Goltsman, Daniela S. A.;
Taylor, David W.

Publication type:

Article

Cas12e orthologs evolve variable structural elements to facilitate dsDNA cleavage.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-54491-9

By:

Li, Danyuan;
Zhang, Shouyue;
Lin, Shuo;
Xing, Wenjing;
Yang, Yun;
Zhu, Fengxia;
Su, Dingding;
Chen, Chunlai;
Liu, Jun-Jie Gogo

Publication type:

Article

USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52250-4

By:

Mackay, Hannah L.;
Stone, Helen R.;
Ronson, George E.;
Ellis, Katherine;
Lanz, Alexander;
Aghabi, Yara;
Walker, Alexandra K.;
Starowicz, Katarzyna;
Garvin, Alexander J.;
Van Eijk, Patrick;
Koestler, Stefan A.;
Anthony, Elizabeth J.;
Piberger, Ann Liza;
Chauhan, Anoop S.;
Conway-Thomas, Poppy;
Vaitsiankova, Alina;
Vijayendran, Sobana;
Beesley, James F.;
Petermann, Eva;
Brown, Eric J.

Publication type:

Article

Hyper-recombination in ribosomal DNA is driven by long-range resection-independent RAD51 accumulation.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52189-6

By:

Gál, Zita;
Boukoura, Stavroula;
Oxe, Kezia Catharina;
Badawi, Sara;
Nieto, Blanca;
Korsholm, Lea Milling;
Geisler, Sille Blangstrup;
Dulina, Ekaterina;
Rasmussen, Anna Vestergaard;
Dahl, Christina;
Lv, Wei;
Xu, Huixin;
Pan, Xiaoguang;
Arampatzis, Stefanos;
Stratou, Danai-Eleni;
Galanos, Panagiotis;
Lin, Lin;
Guldberg, Per;
Bartek, Jiri;
Luo, Yonglun

Publication type:

Article

Yeast EndoG prevents genome instability by degrading extranuclear DNA species.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52147-2

By:

Yu, Yang;
Wang, Xin;
Fox, Jordan;
Yu, Ruofan;
Thakre, Pilendra;
McCauley, Brenna;
Nikoloutsos, Nicolas;
Li, Qian;
Hastings, P. J.;
Dang, Weiwei;
Chen, Kaifu;
Ira, Grzegorz

Publication type:

Article

TracrRNA reprogramming enables direct PAM-independent detection of RNA with diverse DNA-targeting Cas12 nucleases.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50243-x

By:

Jiao, Chunlei;
Peeck, Natalia L.;
Yu, Jiaqi;
Ghaem Maghami, Mohammad;
Kono, Sarah;
Collias, Daphne;
Martinez Diaz, Sandra L.;
Larose, Rachael;
Beisel, Chase L.

Publication type:

Article