Works matching DE "NF-kappa B"

Results: 5000

Periplocin Targets HDAC10 to Inhibit NF-κB Signaling and Induce Apoptosis in Myeloid Leukemia Cells.

Published in:

Journal of Cancer, 2025, v. 16, n. 9, p. 2970, doi. 10.7150/jca.113591

By:

Wenjie Li;
Shuping Lai;
Jingxian Chen;
Ziang Chen;
Yanying Zhou;
Rongfang Wei;
Yan Chen

Publication type:

Article

Orphan receptor GPR153 facilitates vascular damage responses by modulating cAMP levels, YAP/TAZ signaling, and NF-κB activation.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61057-w

By:

Shao, Jingchen;
Kwon, Jeonghyeon;
Wang, Tianpeng;
Günther, Stefan;
Tombor, Lukas S.;
Warwick, Timothy;
Shaheryar, Zaib;
Brandes, Ralf P.;
Dimmeler, Stefanie;
Wenzel, Jan;
Offermanns, Stefan;
Schwaninger, Markus;
Wettschureck, Nina

Publication type:

Article

From syndromic clues to diagnosis: understanding CARD11-driven disorders.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1626065

By:

García-Martínez, Elena;
Schiaffino, María Teresa;
Di Natale, Marisa;
Díaz Luna, María de las Mercedes;
Viteri Álvarez, Daniel Alejandro;
Mejía González, María Alejandra

Publication type:

Article

A review on mesenchymal stem cells and their secretome in hepatocellular carcinogenesis and its related signaling pathways: recent update.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03088-9

By:

Jayachandran, Jayenth;
Rithi, A. T.;
Mitra, Abhijit;
Radhakrishnan, Arunkumar;
Banerjee, Antara;
Duttaroy, Asim K.

Publication type:

Article

UROTENSİN II’NİN İNSAN OSTEOBLAST HÜCRELERİNDE ENFLAMASYONLA İLİŞKİLİ ROLÜ.

Published in:

Journal of Inonu University Health Services Vocational School / İnönü Üniversitesi Sağlık Hizmetleri Meslek Yüksek Okulu Dergisi, 2021, v. 9, n. 1, p. 353, doi. 10.33715/inonusaglik.834716

By:

OKUYAN, Hamza Malik;
TERZİ, Menderes Yusuf;
GÜLBOL DURAN, Gülay;
KALACI, Aydıner

Publication type:

Article

Similar Molecular Features in Two Cases of CARD14‐Associated Papulosquamous Eruption.

Published in:

Australasian Journal of Dermatology, 2025, v. 66, n. 3, p. e171, doi. 10.1111/ajd.14455

By:

Wang, Yumeng;
Wang, Bing;
Chen, Jiawen;
Liang, Fuh‐Miin;
Liu, Haifei;
Yang, Jinxiang;
Li, Ming;
Yao, Zhirong;
Feng, Xiaobo

Publication type:

Article

Cirsiliol alleviates experimental inflammatory bowel disease via restoration of intestinal barrier integrity and inhibition of NF-κB and MAPK pathways.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-09896-x

By:

Gao, Juan;
Li, Haiyang;
Wang, Zhenquan;
Jiang, Gufen;
Pan, Liao;
Jiang, Zhengxuan;
Lei, Xiaohong

Publication type:

Article

Selenium protected NMRI mice against methotrexate induced testicular injury.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-09728-y

By:

Heidari, Razieh;
Gholami, Elham;
Zarasvand, Azita Alasvand;
Mirzaei, Seyed Abbas;
Gholami, Mohammadreza;
Haji Ghasem Kashani, Maryam;
Asadolahi, Arefeh;
Davoodi, Elahe;
Assadollahi, Vahideh

Publication type:

Article

Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IκBα through a phosphoenzyme intermediate.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.98009

By:

Borar, Prateeka;
Biswas, Tapan;
Chaudhuri, Ankur;
Rao, Pallavi T.;
Raychaudhuri, Swasti;
Huxford, Tom;
Chakrabarti, Saikat;
Ghosh, Gourisankar;
Polley, Smarajit

Publication type:

Article

Ameliorative effect of citicoline on cyclophosphamide-induced lung injury.

Published in:

Open Veterinary Journal, 2025, v. 15, n. 5, p. 2218, doi. 10.5455/OVJ.2025.v15.i5.39

By:

Salah, Rania;
El-Sayed, Gehad;
El-Sherbini, El-Said;
El-Adl, Mohamed

Publication type:

Article

Anti-inflammatory Function of Ozonated Ethyl Ester of Unsaturated Fatty Acids.

Published in:

Journal of Oleo Science, 2025, v. 74, n. 6, p. 495, doi. 10.5650/jos.ess25040

By:

Yasunari Kato;
Yuki Manabe;
Nao Inoue;
Koji Nagao;
Toshiharu Nagai;
Tatsuya Sugawara

Publication type:

Article

Remdesivir inhibits endothelial activation and atherosclerosis by coupling TAL1 to TRAF6.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06673-2

By:

Zhang, Hanning;
Li, Ruru;
Huo, Qianqian;
Li, Li;
Li, Min;
Hu, Shunxin;
Ren, Changjie;
Wu, Zongyin;
Zhang, Chenghu

Publication type:

Article

The effects of local and systemic metronidazole on bone healing in mandibular defects: a rat model.

Published in:

BMC Oral Health, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12903-025-06254-1

By:

Alpan, Aysan Lektemur;
Kızıldağ, Alper;
Özmen, Özlem;
Zavrak, Necati;
Özdoğan, Zeynep;
Akpınar, Aysun

Publication type:

Article

Engineering STING Nanoadjuvants for spatiotemporally-tailored innate immunity stimulation and cancer vaccination therapy.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60927-7

By:

Chen, Fangmin;
Zhang, Huijuan;
Li, Shiqin;
Ren, Siyuan;
Huang, Lujia;
Cai, Zhixiong;
Yin, Lichen;
Zheng, Mingyue;
Liu, Xiaolong;
Xu, Zhiai;
Yu, Haijun

Publication type:

Article

Multi-omics and network pharmacology reveal Huayu-Tongbi decoction reduced arthritis-related bone erosion.

Published in:

Chinese Medicine, 2025, v. 20, p. 1, doi. 10.1186/s13020-025-01159-1

By:

Chen, Bozhen;
Yang, Lu;
Wang, Houchun;
Yu, Peng;
Ma, Mengyang;
Chen, Meiqi;
Zhou, Yingyan;
Wu, Jiaqi;
Liang, Huasheng;
Wang, Maojie;
Huang, Runyue;
He, Yiting;
Huang, Qingchun;
He, Xiaohong

Publication type:

Article

Hederasaponin C ameliorates chronic obstructive pulmonary disease pathogenesis by targeting TLR4 to inhibit NF-κB/MAPK signaling pathways.

Published in:

Chinese Medicine, 2025, v. 20, p. 1, doi. 10.1186/s13020-025-01155-5

By:

Ning, Yujie;
Huang, Liting;
Wang, Qin-Qin;
Liu, Lina;
Ni, Xinghua;
Xie, Xiaoyun;
Liu, Jingyu;
Su, Qian;
Yang, Shilin;
Yuan, Renyikun;
Gao, Hongwei

Publication type:

Article

The GLP-1 receptor agonist liraglutide inhibits necroptosis and neuroinflammation in a mouse model of Parkinson's disease with diabetes co-morbidity.

Published in:

Frontiers in Neuroscience, 2025, p. 1, doi. 10.3389/fnins.2025.1596506

By:

Zhang, Xiaomin;
Du, Pengyang;
Bai, Bo;
Feng, Peng;
Lian, Xia;
Hölscher, Christian;
Wang, Yongqing;
Xue, Guofang

Publication type:

Article

A comprehensive guide on the anti-inflammatory activities of Asgand Nagori (Withania somnifera) with special reference to cinnamaldehyde and carvacrol.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-05998-8

By:

Tariq, Tahira;
Yousaf, Arfan;
Sandhu, Mansur Abdullah;
Riaz, Aayesha;
Khan, Asghar;
Akram, Abdul Wahab;
Hussain, Syeda Maryam;
Moaeen-ud-din, Muhammad;
Anees, Sadaf;
Naheed, Ghazala;
Khan, Imtiaz Ahmad;
Rhee, Man Hee;
Saba, Evelyn

Publication type:

Article

Sitagliptin Mitigates Doxorubicin-Induced Cardiac Toxicity in Rats, Targeting TLR4/NF-Kb Signaling Pathway.

Published in:

Egyptian Journal of Hospital Medicine, 2025, v. 99, n. 1, p. 1445, doi. 10.21608/ejhm.2025.421224

By:

Elmorshdy, Shorouk E. M.;
Khodir, Suzan A.;
El-aziz, Noha M. Abd;
Akl, Ghada Hamdy;
Abdalraouf, Mai M.;
Elfakhrany, Amany Tawfik;
Ahmed, Reem Mohammed;
ossama, Yousra;
El-Sawaf, Eman A.;
Shebl, Ghada Zaghloul;
Shawky, Noha O.;
El Menyawi, Menna Allah I.;
Emam, Reem M.

Publication type:

Article

Platelet-rich plasma improves cyclophosphamide-induced interstitial cystitis in rat models through the toll-like receptor 4/nuclear factor-kappa B signalling pathway.

Published in:

Clinical & Experimental Nephrology, 2025, v. 29, n. 7, p. 995, doi. 10.1007/s10157-025-02660-5

By:

Wu, Yufan;
Chen, Lei;
Xu, Minzhe;
Yao, Linya;
Yang, Shiyao;
Ang, Xiaojie;
Chen, Weiguo

Publication type:

Article

The impact of pharmacological agents on neuroinflammation in neurodegenerative diseases.

Published in:

Acta Marisiensis. Seria Medica, 2025, v. 71, n. 2, p. 95, doi. 10.2478/amma-2025-0018

By:

Sharma, Anurag;
Khan, Zoya;
Nath, Rajendra;
Dixit, Rakesh Kumar

Publication type:

Article

Resveratrol: a potential alternative therapeutic agent for patients suffering from chronic obstructive pulmonary disease (COPD).

Published in:

Journal of Asian Natural Products Research, 2025, v. 27, n. 7, p. 951, doi. 10.1080/10286020.2025.2459597

By:

Ren, Ong Yan;
Siddiqui, Yasmeen;
Ansari, Mohammed Tahir;
Ali, Asgar

Publication type:

Article

E3 ubiquitin ligase Smurf1 promotes cardiomyocyte pyroptosis by mediating ubiquitin-dependent degradation of TRIB2 in a rat model of heart failure.

Published in:

International Reviews of Immunology, 2025, v. 44, n. 4, p. 165, doi. 10.1080/08830185.2024.2434058

By:

Liu, Wei;
Cai, Xin;
Duan, Shiying;
Shen, Jihua;
Wu, Jiayuan;
Zhou, Zhengwei;
Yu, Kaili;
He, Caihong;
Wang, Yuqin

Publication type:

Article

It is all c-RELative: a new perspective for a member of the nuclear factor kappa B family Free.

Published in:

Cardiovascular Research, 2025, v. 121, n. 5, p. 688, doi. 10.1093/cvr/cvaf053

By:

Miranda, Jonathan O'Connor;
Parent, Anthony;
Lehoux, Stephanie

Publication type:

Article

Lipid metabolic adaptations during inflammation are controlled by the circadian clock and impaired by light at night.

Published in:

Inflammation Research, 2025, v. 74, n. 1, p. 1, doi. 10.1007/s00011-025-02066-9

By:

Benedikova, Beata;
Sebenova Jerigova, Viera;
Zeman, Michal;
Okuliarova, Monika

Publication type:

Article

Intestinal NF-κB pathway–mediated pyroptosis contributes to endotoxemia-induced intestinal injury.

Published in:

Inflammation Research, 2025, v. 74, n. 1, p. 1, doi. 10.1007/s00011-025-02064-x

By:

Wang, Xinrui;
Lu, Wen;
Cai, Ruibin;
Jiang, Jie;
Wang, Chuyue;
Liao, Jinli;
Zhang, Yongshu;
Li, Danni;
Ye, Zi;
Long, Ming;
Liu, Zhihao

Publication type:

Article

microRNAs 介导的炎症相关信号通路调控骨性关节炎软骨细胞功能的研究进展.

Published in:

Journal of Modern Medicine & Health, 2025, v. 41, n. 6, p. 1469, doi. 10.3969/j.issn.1009-5519.2025.06.037

By:

史振华;
王晓萍;
周明旺;
杨星;
高海源

Publication type:

Article

Update in the clinical utilization of chemoprevention for breast cancer: a narrative review.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1435253

By:

Mansour, Razan;
Abunasser, Mahmoud;
Sharaf, Baha';
Abdel-Razeq, Hikmat

Publication type:

Article

SIRT1-Mediated Epigenetic Protective Mechanisms of Phytosome-Encapsulated Zea mays L. var. ceratina Tassel Extract in a Rat Model of PM2.5-Induced Cardiovascular Inflammation.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5759, doi. 10.3390/ijms26125759

By:

Thukham-Mee, Wipawee;
Wattanathorn, Jintanaporn;
Palachai, Nut

Publication type:

Article

Neuroinflammation: Advancements in Pathophysiology and Therapies.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5664, doi. 10.3390/ijms26125664

By:

Martín-Hernández, David

Publication type:

Article

Triterpenoid CDDO-EA Protects from Hyperglycemia, Hyperinsulinemia, and Obesity by Decreasing Energy Intake.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5485, doi. 10.3390/ijms26125485

By:

Cantu, Austin E.;
Rasa, Cordelia;
Mito, Shizue;
Cantu, Denae;
Lopez-Alvarenga, Juan Carlos;
Rivera-Lopez, Leslie L.;
Rios, Israel;
Abrego-Gonzalez, Ashley;
Reyna, Sara M.

Publication type:

Article

Recent Advances of Shikonin in the Molecular Mechanisms of Anticancer, Anti-Inflammation and Immunoregulation.

Published in:

American Journal of Chinese Medicine, 2025, v. 53, n. 4, p. 1093, doi. 10.1142/S0192415X25500417

By:

Ye, Xiaoyun;
Wu, Xiaohong;
Lian, Siheng;
Cai, Ruina;
Wei, Xianni;
Nan, Tingting;
Cai, Yumei;
Su, Yonglong;
Wei, Jinbao

Publication type:

Article

Astragaloside IV: A Promising Drug to Prevent the Transition from Colitis to Colorectal Cancer.

Published in:

American Journal of Chinese Medicine, 2025, v. 53, n. 4, p. 1065, doi. 10.1142/S0192415X25500405

By:

Ran, Jiayu;
Ai, Yanling;
Ni, Jingxin;
Zhang, Yuanhao;
Chen, Jie;
Wang, Tingyao;
Ma, Jia;
Zheng, Jijun;
Li, Ruilin;
Ma, Xiao;
Wen, Yueqiang;
Zeng, Jinhao

Publication type:

Article

Agmatine Abrogates Tacrolimus-Induced Testicular Injury in Rats.

Published in:

Pharmaceutics, 2025, v. 17, n. 6, p. 703, doi. 10.3390/pharmaceutics17060703

By:

Alharbi, Naif;
Nour, Omnia;
Makled, Mirhan N.;
Nader, Manar

Publication type:

Article

Ferulic Acid as an Anti-Inflammatory Agent: Insights into Molecular Mechanisms, Pharmacokinetics and Applications.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 912, doi. 10.3390/ph18060912

By:

Liu, Jiaying;
Guan, Yu;
Yang, Le;
Fang, Heng;
Sun, Hui;
Sun, Ye;
Yan, Guangli;
Kong, Ling;
Wang, Xijun

Publication type:

Article

Immunology: Splice-tailored to fit the bug.

Published in:

Nature Reviews Microbiology, 2012, v. 10, n. 12, p. 804, doi. 10.1038/nrmicro2922

By:

Papatriantafyllou, Maria

Publication type:

Article

Modulation of NF-κB signalling by microbial pathogens.

Published in:

Nature Reviews Microbiology, 2011, v. 9, n. 4, p. 291, doi. 10.1038/nrmicro2539

By:

Rahman, Masmudur M.;
McFadden, Grant

Publication type:

Article

Analysis of the RelA:CBP/p300 Interaction Reveals Its Involvement in NF-κB-Driven Transcription.

Published in:

PLoS Biology, 2013, v. 11, n. 9, p. 1, doi. 10.1371/journal.pbio.1001647

By:

Mukherjee, Sulakshana P.;
Behar, Marcelo;
Birnbaum, Harry A.;
Hoffmann, Alexander;
Wright, Peter E.;
Ghosh, Gourisankar

Publication type:

Article

Local Ca<sup>2+</sup> Entry Via Orai1 Regulates Plasma Membrane Recruitment of TRPC1 and Controls Cytosolic Ca<sup>2+</sup> Signals Required for Specific Cell Functions.

Published in:

PLoS Biology, 2011, v. 9, n. 3, p. 1, doi. 10.1371/journal.pbio.1001025

By:

Kwong Tai Cheng;
Xibao Liu;
Hwei Ling Ong;
Swaim, William;
Ambudkar, Indu S.

Publication type:

Article

Nuclear factor-κB inhibition improves myocardial contractility in rats with cirrhotic cardiomyopathy.

Published in:

Liver International, 2008, v. 28, n. 5, p. 640, doi. 10.1111/j.1478-3231.2008.01692.x

By:

Hongqun Liu;
Lee, Samuel S.

Publication type:

Article

Endotoxin tolerance in human intrahepatic biliary epithelial cells is induced by upregulation of IRAK-M.

Published in:

Liver International, 2006, v. 26, n. 8, p. 935, doi. 10.1111/j.1478-3231.2006.01325.x

By:

Harada, Kenichi;
Isse, Kumiko;
Sato, Yasunori;
Ozaki, Satoru;
Nakanuma, Yasuni

Publication type:

Article

Basic Studies A protective effect of pyrrolidine dithiocarbamate in a rat model of liver cirrhosis.

Published in:

Liver International, 2004, v. 24, n. 2, p. 169, doi. 10.1111/j.1478-3231.2004.00900.x

By:

Bruck, Rafael;
Schey, Ron;
Aeed, Hussein;
Hochman, Ayala;
Genina, Olga;
Pines, Mark

Publication type:

Article

Inhibition of nuclear factor κB and phosphatidylinositol 3-kinase/Akt is essential for massive hepatocyte apoptosis induced by tumor necrosis factor α in mice.

Published in:

Liver International, 2003, v. 23, n. 5, p. 386, doi. 10.1034/j.1478-3231.2003.00867.x

By:

Imose, Motoaki;
Nagaki, Masahito;
Naiki, Takafumi;
Osawa, Yosuke;
Brenner, David A.;
Asano, Takahiko;
Hayashi, Hideki;
Kato, Tomohiro;
Moriwaki, Hisataka

Publication type:

Article

Tadalafil suppresses LPS‐induced inflammation and improves pregnancy outcomes in a pregnant mouse model.

Published in:

Journal of Obstetrics & Gynaecology Research, 2025, v. 51, n. 1, p. 1, doi. 10.1111/jog.16196

By:

Yoshikawa‐Terada, Kento;
Takayama, Erina;
Uemura, Midori;
Toriyabe, Kuniaki;
Tachibana, Ryota;
Yajima, Hideaki;
Ikeda, Tomoaki;
Kondo, Eiji;
Takeuchi, Hiroki

Publication type:

Article

Human Wharton's jelly‐derived mesenchymal stem cells prevent pregnancy loss in a rat by JAK/STAT‐mediated immunomodulation.

Published in:

Journal of Obstetrics & Gynaecology Research, 2023, v. 49, n. 10, p. 2417, doi. 10.1111/jog.15748

By:

Ding, Xiaoying;
Wu, Rongrong;
Jin, Beibei;
Zhu, Chunyu;
Zhang, Yuquan;
Yang, Xiaoqing

Publication type:

Article

CARD9 Deficiencies Linked to Impaired Neutrophil Functions Against Phialophora verrucosa.

Published in:

Mycopathologia, 2015, v. 179, n. 5/6, p. 347, doi. 10.1007/s11046-015-9877-2

By:

Liang, Pin;
Wang, Xiaowen;
Wang, Runchao;
Wan, Zhe;
Han, Wenling;
Li, Ruoyu

Publication type:

Article

<italic>C11orf95-RELA</italic> fusions and upregulated NF-KB signalling characterise a subset of aggressive supratentorial ependymomas that express L1CAM and nestin.

Published in:

Journal of Neuro-Oncology, 2018, v. 138, n. 1, p. 29, doi. 10.1007/s11060-018-2767-y

By:

Malgulwar, Prit Benny;
Nambirajan, Aruna;
Pathak, Pankaj;
Faruq, Mohammed;
Rajeshwari, Madhu;
Singh, Manmohan;
Suri, Vaishali;
Sarkar, Chitra;
Sharma, Mehar Chand

Publication type:

Article

A phase II trial evaluating the effects and intra-tumoral penetration of bortezomib in patients with recurrent malignant gliomas.

Published in:

Journal of Neuro-Oncology, 2016, v. 129, n. 1, p. 139, doi. 10.1007/s11060-016-2156-3

By:

Raizer, Jeffrey;
Chandler, James;
Ferrarese, Roberto;
Grimm, Sean;
Levy, Robert;
Muro, Kenji;
Rosenow, Joshua;
Helenowski, Irene;
Rademaker, Alfred;
Paton, Martin;
Bredel, Markus

Publication type:

Article

The proteomic response in glioblastoma in young patients.

Published in:

Journal of Neuro-Oncology, 2014, v. 119, n. 1, p. 79, doi. 10.1007/s11060-014-1474-6

By:

Deighton, Ruth;
Le Bihan, Thierry;
Martin, Sarah;
Barrios-Llerena, Martin;
Gerth, Alice;
Kerr, Lorraine;
McCulloch, James;
Whittle, Ian

Publication type:

Article

Temozolomide and irradiation combined treatment-induced Nrf2 activation increases chemoradiation sensitivity in human glioblastoma cells.

Published in:

Journal of Neuro-Oncology, 2014, v. 116, n. 1, p. 41, doi. 10.1007/s11060-013-1260-x

By:

Cong, Zi-Xiang;
wang, Han-Dong;
Zhou, Yuan;
Wang, Jia-Wei;
Pan, Hao;
Zhang, Ding-Ding;
Zhang, Li;
Zhu, Lin

Publication type:

Article