Works about MITOGEN-activated protein kinases

Results: 5000

In Vitro Antioxidant and Anti-Neuroinflammatory Effects of Elsholtzia blanda (Benth.) Benth.

Published in:

Life (2075-1729), 2025, v. 15, n. 6, p. 983, doi. 10.3390/life15060983

By:

Yoon, Yeo Dae;
Shrestha, Krishna K.;
Baek, Seung-Hwa

Publication type:

Article

Integrating network pharmacology and experimental verification to explore the protective effects of Evodia rutaecarpa in ischemic stroke.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0327133

By:

Huang, Zhixuan;
Liu, Jian;
Li, Hui;
Huang, Hengjun;
Ai, Yangwen;
Zhou, Dongyue

Publication type:

Article

Ferulic Acid as an Anti-Inflammatory Agent: Insights into Molecular Mechanisms, Pharmacokinetics and Applications.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 912, doi. 10.3390/ph18060912

By:

Liu, Jiaying;
Guan, Yu;
Yang, Le;
Fang, Heng;
Sun, Hui;
Sun, Ye;
Yan, Guangli;
Kong, Ling;
Wang, Xijun

Publication type:

Article

Protective Effects of Xanthorrhizol-Rich Extracts Against PM-Induced Skin Damage in Human Keratinocytes and 3D-Reconstructed Skin Models.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 808, doi. 10.3390/ph18060808

By:

Kang, Haneul;
Ko, Eun-Ji;
Lee, Dahye;
Kang, Junhui;
Hwang, Jae-Kwan;
Kim, Eunsoo

Publication type:

Article

Speak, friend, and enter: signalling systems that promote beneficial symbiotic associations in plants.

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 4, p. 252, doi. 10.1038/nrmicro2990

By:

Oldroyd, Giles E. D.

Publication type:

Article

The Polarity Protein Scribble Regulates Myelination and Remyelination in the Central Nervous System.

Published in:

PLoS Biology, 2015, v. 13, n. 3, p. 1, doi. 10.1371/journal.pbio.1002107

By:

Jarjour, Andrew A.;
Boyd, Amanda;
Dow, Lukas E.;
Holloway, Rebecca K.;
Goebbels, Sandra;
Humbert, Patrick O.;
Williams, Anna;
ffrench-Constant, Charles

Publication type:

Article

Growth Cone <i>MKK7</i> mRNA Targeting Regulates MAP1b-Dependent Microtubule Bundling to Control Neurite Elongation

Published in:

PLoS Biology, 2012, v. 10, n. 12, p. 1, doi. 10.1371/journal.pbio.1001439

By:

Feltrin, Daniel;
Fusco, Ludovico;
Witte, Harald;
Moretti, Francesca;
Martin, Katrin;
Letzelter, Michel;
Fluri, Erika;
Scheiffele, Peter;
Pertz, Olivier

Publication type:

Article

Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition.

Published in:

PLoS Biology, 2008, v. 6, n. 10, p. 2237, doi. 10.1371/journal.pbio.0060253

By:

Silva, Jose;
Barrandon, Ornella;
Nichols, Jennifer;
Kawaguchi, Jitsutaro;
Theunissen, Thorold W.;
Smith, Austin

Publication type:

Article

The N. gonorrhoeae Type IV Pilus Stimulates Mechanosensitive Pathways and Cytoprotection through a pilT-Dependent Mechanism.

Published in:

PLoS Biology, 2005, v. 3, n. 3, p. 1, doi. 10.1371/journal.pbio.0030100

By:

Howie, Heather L;
Glogauer, Michael;
So, Magdalene

Publication type:

Article

Altered factor VII activating protease expression in murine hepatic fibrosis and its influence on hepatic stellate cells.

Published in:

Liver International, 2009, v. 29, n. 5, p. 686, doi. 10.1111/j.1478-3231.2008.01897.x

By:

Roderfeld, Martin;
Weiskirchen, Ralf;
Atanasova, Srebrena;
Gressner, Axel M.;
Preissner, Klaus T.;
Roeb, Elke;
Kanse, Sandip M.

Publication type:

Article

Human intrahepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-κB and -MAPK signaling pathways.

Published in:

Liver International, 2006, v. 26, n. 4, p. 467, doi. 10.1111/j.1478-3231.2006.01254.x

By:

Yokoyama, Terufumi;
Komori, Atsumasa;
Nakamura, Minoru;
Takii, Yasushi;
Kamihira, Takashi;
Shimoda, Shinji;
Mori, Tsuyoshi;
Fujiwara, Shinsuke;
Koyabu, Makiko;
Taniguchi, Ken;
Fujioka, Hikaru;
Migita, Kiyoshi;
Yatsuhashi, Hiroshi;
Ishibashi, Hiromi

Publication type:

Article

Effect of irisin on ovarian phosphatidylinositol‐3‐kinase/protein kinase B signaling pathway and mitogen‐activated protein kinase/extracellular signal‐regulated kinase pathways of rats with polycystic ovary syndrome.

Published in:

Journal of Obstetrics & Gynaecology Research, 2024, v. 50, n. 10, p. 1945, doi. 10.1111/jog.16076

By:

Li, Cheng‐gang;
Zhou, Li;
Zhang, Ying‐jun;
Li, Yong;
Zhao, Li‐yan

Publication type:

Article

Effects of MPK3 and MPK6 kinases on the chloroplast architecture and function induced by cold acclimation in Arabidopsis.

Published in:

Photosynthesis Research, 2021, v. 149, n. 1/2, p. 201, doi. 10.1007/s11120-021-00852-0

By:

Saucedo-García, Mariana;
González-Córdova, Carla D.;
Ponce-Pineda, I. Giordano;
Cano-Ramírez, Dora;
Romero-Colín, Fernanda M.;
Arroyo-Pérez, Erik E.;
King-Díaz, Beatriz;
Zavafer, Alonso;
Gavilanes-Ruíz, Marina

Publication type:

Article

Computing maximal and minimal trap spaces of Boolean networks.

Published in:

Natural Computing, 2015, v. 14, n. 4, p. 535, doi. 10.1007/s11047-015-9520-7

By:

Klarner, Hannes;
Bockmayr, Alexander;
Siebert, Heike

Publication type:

Article

Inflammation Induced by Candida parapsilosis in THP-1 Cells and Human Peripheral Blood Mononuclear Cells (PBMCs).

Published in:

Mycopathologia, 2017, v. 182, n. 11/12, p. 1015, doi. 10.1007/s11046-017-0187-8

By:

Duan, Zhimin;
Chen, Xu;
Du, Leilei;
Liu, Caixia;
Zeng, Rong;
Chen, Qing;
Li, Min

Publication type:

Article

Proteome Profile of Aspergillus terreus Conidia at Germinating Stage: Identification of Probable Virulent Factors and Enzymes from Mycotoxin Pathways.

Published in:

Mycopathologia, 2017, v. 182, n. 9/10, p. 771, doi. 10.1007/s11046-017-0161-5

By:

Thakur, Raman;
Shankar, Jata

Publication type:

Article

HOG-MAPK Signaling Regulates the Adaptive Responses of Aspergillus fumigatus to Thermal Stress and Other Related Stress.

Published in:

Mycopathologia, 2012, v. 174, n. 4, p. 273, doi. 10.1007/s11046-012-9557-4

By:

Ji, Yajuan;
Yang, Fang;
Ma, Dongmei;
Zhang, Jinqing;
Wan, Zhe;
Liu, Wei;
Li, Ruoyu

Publication type:

Article

Selumetinib for plexiform neurofibromas in neurofibromatosis type 1: a single-institution experience.

Published in:

Journal of Neuro-Oncology, 2020, v. 147, n. 2, p. 459, doi. 10.1007/s11060-020-03443-6

By:

Espírito Santo, Vera;
Passos, João;
Nzwalo, Hipólito;
Carvalho, Inês;
Santos, Filipa;
Martins, Carmo;
Salgado, Lucília;
Silva, Conceição e;
Vinhais, Sofia;
Vilares, Miguel;
Salgado, Duarte;
Nunes, Sofia

Publication type:

Article

Trametinib for progressive pediatric low-grade gliomas.

Published in:

Journal of Neuro-Oncology, 2018, v. 140, n. 2, p. 435, doi. 10.1007/s11060-018-2971-9

By:

Kondyli, Maria;
Larouche, Valérie;
Saint-Martin, Christine;
Ellezam, Benjamin;
Pouliot, Lauranne;
Sinnett, Daniel;
Legault, Geneviève;
Crevier, Louis;
Weil, Alex;
Farmer, Jean-Pierre;
Jabado, Nada;
Perreault, Sébastien

Publication type:

Article

Elevated levels of p-Mnk1, p-eIF4E and p-p70S6K proteins are associated with tumor recurrence and poor prognosis in astrocytomas.

Published in:

Journal of Neuro-Oncology, 2017, v. 131, n. 3, p. 485, doi. 10.1007/s11060-016-2327-2

By:

Fan, Weibing;
Wang, Weiyuan;
Mao, Xinfa;
Chu, Shuzhou;
Feng, Juan;
Xiao, Desheng;
Zhou, Jianhua;
Fan, Songqing

Publication type:

Article

Combined BRAF and MEK blockade for BRAF-mutant gliomas.

Published in:

Journal of Neuro-Oncology, 2017, v. 131, n. 3, p. 495, doi. 10.1007/s11060-016-2333-4

By:

Zhang, Jie;
Yao, Tsun-Wen;
Hashizume, Rintaro;
Hariono, Sujatmi;
Barkovich, Krister;
Fan, Qi-Wen;
Prados, Michael;
James, C.;
Weiss, William;
Nicolaides, Theodore

Publication type:

Article

Rapid progression of intracranial melanoma metastases controlled with combined BRAF/MEK inhibition after discontinuation of therapy: a clinical challenge.

Published in:

Journal of Neuro-Oncology, 2016, v. 129, n. 3, p. 389, doi. 10.1007/s11060-016-2196-8

By:

Cagney, Daniel;
Alexander, Brian;
Hodi, F.;
Buchbinder, Elizabeth;
Ott, Patrick;
Aizer, Ayal

Publication type:

Article

Disseminated glioneuronal tumors occurring in childhood: treatment outcomes and BRAF alterations including V600E mutation.

Published in:

Journal of Neuro-Oncology, 2016, v. 128, n. 2, p. 293, doi. 10.1007/s11060-016-2109-x

By:

Dodgshun, Andrew;
SantaCruz, Nadine;
Hwang, Jaeho;
Ramkissoon, Shakti;
Malkin, Hayley;
Bergthold, Guillaume;
Manley, Peter;
Chi, Susan;
MacGregor, Duncan;
Goumnerova, Liliana;
Sullivan, Michael;
Ligon, Keith;
Beroukhim, Rameen;
Herrington, Betty;
Kieran, Mark;
Hansford, Jordan;
Bandopadhayay, Pratiti

Publication type:

Article

miR-429 inhibits glioma invasion through BMK1 suppression.

Published in:

Journal of Neuro-Oncology, 2015, v. 125, n. 1, p. 43, doi. 10.1007/s11060-015-1887-x

By:

Chen, Weiyi;
Zhang, Baogang;
Guo, Wenjun;
Gao, Linlin;
Shi, Lihong;
Li, Hongli;
Lu, Shijun;
Liu, Yuqing;
Li, Xiaolong

Publication type:

Article

Survival patterns following brain metastases for patients with melanoma in the MAP-kinase inhibitor era.

Published in:

Journal of Neuro-Oncology, 2015, v. 123, n. 1, p. 75, doi. 10.1007/s11060-015-1761-x

By:

Wattson, Daniel;
Sullivan, Ryan;
Niemierko, Andrzej;
Merritt, Ryan;
Lawrence, Donald;
Oh, Kevin;
Flaherty, Keith;
Shih, Helen

Publication type:

Article

Mitogenic signalling in the absence of epidermal growth factor receptor activation in a human glioblastoma cell line.

Published in:

Journal of Neuro-Oncology, 2013, v. 115, n. 3, p. 323, doi. 10.1007/s11060-013-1232-1

By:

Wang, Meng;
Maier, Patrick;
Wenz, Frederik;
Giordano, Frank Anton;
Herskind, Carsten

Publication type:

Article

BRAF alterations in pediatric low grade gliomas and mixed neuronal-glial tumors.

Published in:

Journal of Neuro-Oncology, 2013, v. 113, n. 3, p. 353, doi. 10.1007/s11060-013-1131-5

By:

Dimitriadis, Efthymios;
Alexiou, George;
Tsotsou, Panagiota;
Simeonidi, Efthymia;
Stefanaki, Kalliopi;
Patereli, Amalia;
Prodromou, Neofytos;
Pandis, Nikolaos

Publication type:

Article

Human chorionic gonadotropin β induces cell motility via ERK1/2 and MMP-2 activation in human glioblastoma U87MG cells.

Published in:

Journal of Neuro-Oncology, 2013, v. 111, n. 3, p. 237, doi. 10.1007/s11060-012-1017-y

By:

Li, Zongwen;
Du, Lianlian;
Li, Chunliu;
Wu, Wei

Publication type:

Article

Hyperoxia resensitizes chemoresistant human glioblastoma cells to temozolomide.

Published in:

Journal of Neuro-Oncology, 2012, v. 109, n. 3, p. 467, doi. 10.1007/s11060-012-0923-3

By:

Sun, Stella;
Lee, Derek;
Lee, Nikki;
Pu, Jenny;
Wong, Stanley;
Lui, W.;
Fung, C.;
Leung, Gilberto

Publication type:

Article

Mechanism for the induction of cell death in ONS-76 medulloblastoma cells by Zhangfei/CREB-ZF.

Published in:

Journal of Neuro-Oncology, 2012, v. 109, n. 3, p. 485, doi. 10.1007/s11060-012-0927-z

By:

Bodnarchuk, Timothy;
Napper, Scott;
Rapin, Noreen;
Misra, Vikram

Publication type:

Article

Valproic acid affected the survival and invasiveness of human glioma cells through diverse mechanisms.

Published in:

Journal of Neuro-Oncology, 2012, v. 109, n. 1, p. 23, doi. 10.1007/s11060-012-0871-y

By:

Chen, Yun;
Tsai, Ya-Hui;
Tseng, Sheng-Hong

Publication type:

Article

p38 MAPK inhibitors attenuate pro-inflammatory cytokine production and the invasiveness of human U251 glioblastoma cells.

Published in:

Journal of Neuro-Oncology, 2012, v. 109, n. 1, p. 35, doi. 10.1007/s11060-012-0875-7

By:

Yeung, Yiu;
Bryce, Nicole;
Adams, Seray;
Braidy, Nady;
Konayagi, Mari;
McDonald, Kerrie;
Teo, Charles;
Guillemin, Gilles;
Grewal, Thomas;
Munoz, Lenka

Publication type:

Article

A phase II study of the Ras-MAPK signaling pathway inhibitor TLN-4601 in patients with glioblastoma at first progression.

Published in:

Journal of Neuro-Oncology, 2012, v. 107, n. 2, p. 343, doi. 10.1007/s11060-011-0747-6

By:

Mason, Warren;
Belanger, Karl;
Nicholas, Garth;
Vallières, Isabelle;
Mathieu, David;
Kavan, Petr;
Desjardins, Annick;
Omuro, Antonio;
Reymond, Didier

Publication type:

Article

Epidermal growth factor induces matrix metalloproteinase-1 (MMP-1) expression and invasion in glioma cell lines via the MAPK pathway.

Published in:

Journal of Neuro-Oncology, 2011, v. 104, n. 3, p. 679, doi. 10.1007/s11060-011-0549-x

By:

Anand, M.;
Meter, T.;
Fillmore, H.

Publication type:

Article

Increased STAT-3 and synchronous activation of Raf-1-MEK-1-MAPK, and phosphatidylinositol 3-Kinase-Akt-mTOR pathways in atypical and anaplastic meningiomas.

Published in:

Journal of Neuro-Oncology, 2009, v. 92, n. 2, p. 129, doi. 10.1007/s11060-008-9746-7

By:

Mahlon Johnson;
Mary O’Connell;
Fran Vito;
Robert Bakos

Publication type:

Article

Antifungal effects of lycorine on Botrytis cinerea and possible mechanisms.

Published in:

Biotechnology Letters, 2021, v. 43, n. 7, p. 1503, doi. 10.1007/s10529-021-03128-8

By:

Zhao, Shixue;
Guo, Yanhua;
Wang, Qiannan;
An, Bang

Publication type:

Article

miR-19a mitigates hypoxia/reoxygenation-induced injury by depressing CCL20 and inactivating MAPK pathway in human embryonic cardiomyocytes.

Published in:

Biotechnology Letters, 2021, v. 43, n. 2, p. 393, doi. 10.1007/s10529-020-03045-2

By:

Fu, Qiang;
Mo, Tao-Ran;
Hu, Xiao-Yang;
Fu, Yin;
Li, Ji

Publication type:

Article

The disruption of the MAPKK gene triggering the synthesis of flavonoids in endophytic fungus Phomopsis liquidambaris.

Published in:

Biotechnology Letters, 2021, v. 43, n. 1, p. 119, doi. 10.1007/s10529-020-03042-5

By:

Yang, Qian;
Wu, Mei;
Zhu, Ya-Li;
Yang, Ya-Qiong;
Mei, Yan-Zhen;
Dai, Chuan-Chao

Publication type:

Article

Curcusone C induces apoptosis in endometrial cancer cells via mitochondria-dependent apoptotic and ERK pathway.

Published in:

Biotechnology Letters, 2021, v. 43, n. 1, p. 329, doi. 10.1007/s10529-020-03027-4

By:

An, Junxia;
Li, Lifei;
Zhang, Xuehong

Publication type:

Article

Identification of key pathways and differentially expressed genes in bronchopulmonary dysplasia using bioinformatics analysis.

Published in:

Biotechnology Letters, 2020, v. 42, n. 12, p. 2569, doi. 10.1007/s10529-020-02986-y

By:

Yan, Weiheng;
Jiang, Miaomiao;
Zheng, Jun

Publication type:

Article

The marine Gram-negative bacterium Novosphingobium sp. PP1Y as a potential source of novel metabolites with antioxidant activity.

Published in:

Biotechnology Letters, 2019, v. 41, n. 2, p. 273, doi. 10.1007/s10529-018-02636-4

By:

Petruk, Ganna;
Roxo, Mariana;
De Lise, Federica;
Mensitieri, Francesca;
Notomista, Eugenio;
Wink, Michael;
Izzo, Viviana;
Monti, Daria Maria

Publication type:

Article

Expression of adenylate kinase fused MEK1R4F in Escherichia coli and its application in ERK phosphorylation.

Published in:

Biotechnology Letters, 2017, v. 39, n. 10, p. 1553, doi. 10.1007/s10529-017-2385-3

By:

Yang, Fang;
Li, Hongtao

Publication type:

Article

Nr4a1 promotes renal interstitial fibrosis by regulating the p38 MAPK phosphorylation.

Published in:

Molecular Medicine, 2023, v. 29, n. 1, p. 1, doi. 10.1186/s10020-023-00657-y

By:

Tao, Yilin;
Tang, Chengyuan;
Wei, Ju;
Shan, Yi;
Fang, Xi;
Li, Ying

Publication type:

Article

AAV-glycine receptor α3 alleviates CFA-induced inflammatory pain by downregulating ERK phosphorylation and proinflammatory cytokine expression in SD rats.

Published in:

Molecular Medicine, 2023, v. 29, n. 1, p. 1, doi. 10.1186/s10020-023-00606-9

By:

Wang, Hung-Chen;
Cheng, Kuang-I;
Tseng, Kuang-Yi;
Kwan, Aij-Lie;
Chang, Lin-Li

Publication type:

Article

The mechanism of nicotinamide on reducing acute lung injury by inhibiting MAPK and NF-κB signal pathway.

Published in:

Molecular Medicine, 2021, v. 27, n. 1, p. 1, doi. 10.1186/s10020-021-00376-2

By:

Zhang, Qun;
Li, Junyao;
Zhong, Haixia;
Xu, Yanling

Publication type:

Article

ACTH Induces ERK 1/2 Activation in Rat Adrenal Primary Cultures.

Published in:

Microscopy & Microanalysis, 2008, v. 14, n. S3, p. 101, doi. 10.1017/S1431927608089526

By:

Rodrigues, A.R.;
Gouveia, A.M.;
Ferreira, J.G.;
Almeida, H.

Publication type:

Article

Benzimidazole‐based structure optimization to discover novel anti‐gastric cancer agents targeting ROS/MAPK pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 7, p. 1, doi. 10.1002/jbt.23762

By:

Jia, Gang;
Wang, Yuanying;
Wang, Jikuan;
Yu, Bingxin;
Zhao, Haiyang;
Zhao, Ze;
Zhao, Wenming;
Gao, Ya;
Wang, Bo;
Song, Zhiyu

Publication type:

Article

Naringin protects against paclitaxel‐induced toxicity in rat testicular tissues by regulating genes in pro‐inflammatory cytokines, oxidative stress, apoptosis, and JNK/MAPK signaling pathways.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 7, p. 1, doi. 10.1002/jbt.23751

By:

Kankılıç, Nazım Abdülkadir;
Küçükler, Sefa;
Gür, Cihan;
Akarsu, Serkan Ali;
Akaras, Nurhan;
Şimşek, Hasan;
İleritürk, Mustafa;
Kandemir, Fatih Mehmet

Publication type:

Article

Biochanin A mitigates ulcerative colitis and intestinal inflammation in mice by inhibiting MAPK/NF‐kB (p65) axis.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 6, p. 1, doi. 10.1002/jbt.23738

By:

Kulhari, Uttam;
Rajanan, Ashitha;
Ambujakshan, Anju;
Verma, Smriti;
Mugale, Madhav Nilakanth;
Sahu, Bidya Dhar

Publication type:

Article

Icariin alleviates high‐fat diet‐induced nonalcoholic fatty liver disease via up‐regulating miR‐206 to mediate NF‐κB and MAPK pathways.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 1, p. 1, doi. 10.1002/jbt.23566

By:

Zhao, Hang;
Tian, Hongyang

Publication type:

Article