Works about MENDELIAN randomization

Results: 1487

Association of Sleep, Inflammation and Female Infertility: A Cross‐Sectional Survey and Genetic Approach.

Published in:

Brain & Behavior, 2025, v. 15, n. 6, p. 1, doi. 10.1002/brb3.70627

By:

Xin, Xin;
Li, Jiaxi;
Zhang, Jinfu;
Wu, Haicui

Publication type:

Article

Proteome‐Wide and Immune Cell Phenotype Mendelian Randomization Highlights Immune Involvement in Genetic Generalized Epilepsy.

Published in:

Brain & Behavior, 2025, v. 15, n. 6, p. 1, doi. 10.1002/brb3.70625

By:

Gui, Jianxiong;
Chu, Hongyuan;
Zhang, Junjiao;
Li, Xiao;
Liu, Wenwei;
Li, Renqiuguo;
Zhang, Fan;
Dong, Meiyu;
Gao, Kai;
Luo, Huaxia;
Jiang, Yuwu

Publication type:

Article

Effects of Oxidative Stress Gene Protein, Expression, and DNA Methylation on Multiple Sclerosis: A Multi‐Omics Mendelian Randomized Study.

Published in:

Brain & Behavior, 2025, v. 15, n. 6, p. 1, doi. 10.1002/brb3.70606

By:

Li, Yang;
Wang, Yushi;
Wang, Shuning;
Zhu, Hui

Publication type:

Article

Exploring the Causal Association Between 91 Circulating Inflammatory Proteins and Neurodegenerative Diseases: A Bidirectional Two‐Sample Mendelian Randomization and Bioinformatics Analysis.

Published in:

Brain & Behavior, 2025, v. 15, n. 6, p. 1, doi. 10.1002/brb3.70586

By:

Gong, Ziwei;
Cao, Rong;
Zhu, Hong

Publication type:

Article

Woolf et al's "GWAS by subtraction" is not useful for cross-generational Mendelian randomization studies.

Published in:

BMC Research Notes, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13104-025-07326-9

By:

Evans, David M;
Smith, George Davey;
Moen, Gunn-Helen

Publication type:

Article

Myasthenia Gravis and Depression: A Multifaceted Exploration through Omics and Beyond.

Published in:

Alpha Psychiatry, 2025, v. 26, n. 1, p. 1, doi. 10.31083/AP38754

By:

Zheng Guo;
Yulu Zheng;
Balmer, Lois

Publication type:

Article

Rib and Sternum Fractures From Falls: Global Burden of Disease and Predictions.

Published in:

Biomedical Engineering & Computational Biology, 2025, p. 1, doi. 10.1177/11795972251350223

By:

Huang, Zhanghao;
Zhu, Jun

Publication type:

Article

Editorial: Multi-target drug discovery and design for complex health disorders.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1633600

By:

Badria, Farid A.;
De Filippis, Barbara;
El-Magd, Mohammed Abu;
Elbadawi, Mostafa M.;
Hamdi, Abdelrahman;
Elgazar, Abdullah A.

Publication type:

Article

Physical activity and risk of epilepsy: A 2‐sample Mendelian randomization study.

Published in:

Epileptic Disorders, 2025, v. 27, n. 3, p. 430, doi. 10.1002/epd2.70024

By:

Yang, Cheng;
Wang, Mengmeng;
Chen, Xin;
Yao, Jianrong;
Ma, Yazhou;
Lian, Xuegan

Publication type:

Article

SPHK1 - S1p Signaling Drives Fibrocyte-Mediated Pulmonary Fibrosis: Mechanistic Insights and Therapeutic Potential.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 859, doi. 10.3390/ph18060859

By:

Lu, Fei;
Wang, Gaoming;
Yang, Xiangzhe;
Luo, Jing;
Ma, Haitao;
Pan, Liangbin;
Yao, Yu;
Xie, Kai

Publication type:

Article

Exploring the Potential Association Between Inhaled Corticosteroid and Face Aging Risk: A Mendelian Randomization Study.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 846, doi. 10.3390/ph18060846

By:

Li, Junpeng;
Liu, Yaqiong;
Wu, Gujie;
Yin, Shanye;
Cheng, Lin;
Deng, Wenjun

Publication type:

Article

Association of intrahepatic cholestasis of pregnancy with preterm birth and low birth weight in offspring: A prospective cohort and Mendelian randomization study.

Published in:

Journal of Obstetrics & Gynaecology Research, 2025, v. 51, n. 6, p. 1, doi. 10.1111/jog.16348

By:

Tang, Jiapeng;
Sun, Mengting;
Luo, Manjun;
Chen, Ye;
Chen, Yige;
Wei, Jianhui;
Ruan, Xiaorui;
Wang, Tingting;
Qin, Jiabi

Publication type:

Article

Eosinophils and other blood cell traits in the risk of infertility population: A Mendelian randomization analysis.

Published in:

Journal of Obstetrics & Gynaecology Research, 2025, v. 51, n. 6, p. 1, doi. 10.1111/jog.16347

By:

Yi, Shiqi;
Feng, Ying;
Zhang, Yuping;
Zhang, Linyu;
Sun, Xinrui;
Zhang, Yi;
Ma, Qianhong;
Ma, Fang

Publication type:

Article

Genetic liability to gut microbiota and inflammatory cytokines in relation to systemic lupus erythematosus risk: a multi-omics study.

Published in:

Clinical Rheumatology, 2025, v. 44, n. 6, p. 2257, doi. 10.1007/s10067-025-07435-7

By:

Lu, Rui-Ling;
Chen, Yan-Ran;
Yang, Xu-Fa;
Huang, Xin-Yi;
Liu, Dong-Zhou;
Hong, Xiao-Ping

Publication type:

Article

Association of regional adiposity distribution with risk of autoimmune diseases.

Published in:

Clinical Rheumatology, 2025, v. 44, n. 6, p. 2541, doi. 10.1007/s10067-025-07426-8

By:

Fan, Rui;
Zhang, Zhihan;
Huang, Qinlian;
Liu, Linqi;
Que, Wenjun;
Lu, Dan;
Jing, Sisi;
Gan, Yaoqi;
Liu, Shiyi;
Xiao, Fei

Publication type:

Article

Association between systemic lupus erythematosus and cardiovascular health based on genetic data.

Published in:

Clinical Rheumatology, 2025, v. 44, n. 6, p. 2277, doi. 10.1007/s10067-025-07396-x

By:

Wang, Rui;
Cui, Xiao-Wei;
Zhang, Miao;
Xu, Jian;
Bu, Chan-Yuan;
Zhao, Xiang-Yang

Publication type:

Article

Integration of metabolomics and genomics implicates a causality between 1398 blood metabolites and gout.

Published in:

Clinical Rheumatology, 2025, v. 44, n. 5, p. 2053, doi. 10.1007/s10067-025-07402-2

By:

Fan, Mingyuan;
Yun, Zhangjun;
Yuan, Jiushu;
Lu, Dingyi;
Xie, Hongyan;
Yuan, Haipo;
Gao, Hong

Publication type:

Article

Mendelian randomization and mediation analysis reveal the role of immune cell subsets in the causal pathways between blood cell perturbation responses and rheumatoid arthritis.

Published in:

Clinical Rheumatology, 2025, v. 44, n. 4, p. 1537, doi. 10.1007/s10067-025-07387-y

By:

Li, Feng;
Xian, Dehai;
Yang, Kaiwen

Publication type:

Article

Role of miRNAs in the pathogenesis of psoriasis and psoriatic arthritis: a genome-wide Mendelian randomization study.

Published in:

Clinical Rheumatology, 2025, v. 44, n. 4, p. 1607, doi. 10.1007/s10067-025-07374-3

By:

Li, Chanxiu;
Sun, Zhanxue

Publication type:

Article

Investigating the causal relationship between rheumatoid arthritis and cardiovascular disease: A Mendelian randomization study.

Published in:

Clinical Rheumatology, 2025, v. 44, n. 3, p. 1057, doi. 10.1007/s10067-025-07357-4

By:

Xie, Xintong;
Wei, Guangliang;
Tang, Zhenboyang;
Chen, Huidong;
Lin, Xiru;
Huang, Chunyan;
Yu, Hao;
He, Youxian;
Li, Mengxiang;
Zhang, Xue;
He, Chengsong;
He, Yue;
Chen, Jie

Publication type:

Article

Mediating effect of X-26109 on the causal relationship between CD14<sup>+</sup> CD16<sup>−</sup> monocyte activation complex and rheumatoid arthritis in Europe.

Published in:

Clinical Rheumatology, 2025, v. 44, n. 3, p. 1095, doi. 10.1007/s10067-025-07300-7

By:

Wang, Han;
Chu, Jinjie;
Wang, Yan;
Wu, Yongqin;
Zhou, Wenchao

Publication type:

Article

Causal association between bone mineral density and the risk of joint replacement in patients with osteoarthritis: a Mendelian randomization study.

Published in:

Clinical Rheumatology, 2025, v. 44, n. 2, p. 823, doi. 10.1007/s10067-024-07289-5

By:

Zhu, Rui;
Xing, Xing;
Bian, Jingyuan;
Zhang, Xiaoyue;
Ge, Liru;
Cai, Guoqi

Publication type:

Article

Identifying the genetic association between rheumatoid arthritis and the risk of pulmonary arterial hypertension.

Published in:

Clinical Rheumatology, 2025, v. 44, n. 1, p. 153, doi. 10.1007/s10067-024-07258-y

By:

Yang, Leilei;
Wang, Xiaoqin;
Gu, Bingjie;
Su, Dinglei

Publication type:

Article

Causal effects of circulating inflammatory proteins on knee and hip osteoarthritis: A two sample Mendelian randomization study.

Published in:

Clinical Rheumatology, 2025, v. 44, n. 1, p. 465, doi. 10.1007/s10067-024-07232-8

By:

Lin, Rongjie;
Zheng, Qingcong;
Zhang, Rui;
Liu, Quan;
Lin, Jianlong;
Weng, Shaohuang;
Chen, Min

Publication type:

Article

Rheumatoid arthritis and gliostatin: a two-sample Mendelian randomization analysis and RT-PCR validation.

Published in:

Clinical Rheumatology, 2025, v. 44, n. 1, p. 125, doi. 10.1007/s10067-024-07164-3

By:

Xia, Zhongbin;
Zong, Siwen;
Zhou, Sibin;
Rao, Yujie;
Li, Zhenjiang

Publication type:

Article

Exploring genetic associations in systemic lupus erythematosus through Mendelian randomization: implications for novel biomarkers and therapeutic targets.

Published in:

Clinical Rheumatology, 2025, v. 44, n. 1, p. 193, doi. 10.1007/s10067-024-07094-0

By:

Liu, Qi;
Liu, Yuyang;
Feng, Hui;
Zhao, Lin;
Wan, Tao

Publication type:

Article

Causal relationship between strenuous exercise and muscle injury: a Mendelian randomization study with dual samples.

Published in:

European Journal of Applied Physiology, 2025, v. 125, n. 4, p. 989, doi. 10.1007/s00421-024-05669-y

By:

Huang, Xin;
Huang, Longxiang;
Liu, Changhua

Publication type:

Article

Genetic determinants of proteomic aging.

Published in:

NPJ Aging, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41514-025-00205-4

By:

Mörseburg, Alexander;
Zhao, Yajie;
Kentistou, Katherine A.;
Perry, John R. B.;
Ong, Ken K.;
Day, Felix R.

Publication type:

Article

基于双样本孟德尔随机化探讨结直肠癌与常见精神类疾病的因果关系.

Published in:

Cancer Research on Prevention & Treatment, 2025, v. 52, n. 6, p. 496, doi. 10.3971/j.issn.1000-8578.2025.24.1154

By:

姚源;
杨明泽;
李晨;
程海波

Publication type:

Article

白介素与妇科肿瘤发病风险相关的孟德尔随机化分析.

Published in:

Cancer Research on Prevention & Treatment, 2025, v. 52, n. 6, p. 511, doi. 10.3971/j.issn.1000-8578.2025.24.0994

By:

周欣颖;
张虎;
戴海燕

Publication type:

Article

Exploring the causal relationship between CX3CL1 and prostate cancer prognosis using Mendelian randomization.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03001-4

By:

Li, Weisheng;
Xia, Baoguo;
Chu, Weixin;
Lu, Likui;
Liu, Xuedong

Publication type:

Article

Vitamin D and risk of thyroid cancer: a two-sample Mendelian randomization study.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03002-3

By:

Shi, Yunbin;
Qian, Lihui;
Ma, Tao;
Huang, Juntao

Publication type:

Article

Mendelian randomization studies of gastric cancer reveal potential risk factors, promising biomarkers and therapeutic targets.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02954-w

By:

He, Maowei;
Duan, Yanting;
Zhang, Yuanyan;
Qian, Chao;
Jin, Jiawei

Publication type:

Article

Identification of prostate cancer potential therapeutic targets and virtual drug screening through combined Mendelian randomization study, Bayesian colocalization and molecular docking.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02968-4

By:

Liang, Zilong;
Hu, Conglei;
Pang, Haofeng;
Shao, Yongxiang;
Kong, Lingchen;
Cheng, Meng;
Du, Haiyang;
Feng, Tianxi;
Fan, Zudu;
Yao, Liping;
Liu, Fei

Publication type:

Article

Identification of biomarkers associated with exhausted CD8 + T cells in the tumor microenvironment of intrahepatic cholangiocarcinoma based on Mendelian randomization and bioinformatics analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02970-w

By:

Feng, LiuXing;
Yuan, Quan;
Yu, Hao;
Ye, RongJie;
Xie, ZhenHao;
Xu, JiaHuan;
Li, XiuDong;
Wang, ShuangJia

Publication type:

Article

Mendelian randomization analysis of immune cell characteristics and genetic variants in cervical cancer risk: a genome-wide association study.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02876-7

By:

Zhang, Yu;
Ji, Limei;
Yang, Shuo

Publication type:

Article

Dynamics of mitochondrial DNA copy number regulation in relation to gastric cancer survival.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02825-4

By:

Yang, Qizhou;
Zhao, Tian;
Han, Yuying;
Ji, Zhengguo;
Ye, Haihong

Publication type:

Article

Deciphering the risk of developing liver cancer following gastric cancer diagnosis with genetic evidence: a Mendelian randomization analysis in an East Asian population.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01938-0

By:

Chen, Jiansheng;
Zeng, Aiming;
Yu, Yunzhe;
Liao, Liqun;
Huang, Siwei;
Sun, Sida;
Wu, Weijie

Publication type:

Article

A Multi-omic study integrating plasma protein, multiple tissues, and single-cell identifies RNASET2 as a key gene for lung cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01899-4

By:

Shi, Jiaxin;
Zhang, Linyou

Publication type:

Article

Plasma miRNAs in polycystic ovary syndrome drive endometrial cancer progression: insights into molecular pathways and therapeutic targets.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01861-4

By:

Lai, Xuedan;
Wu, Ling;
Lin, Peihong;
You, Lijiao;
Ye, Jianwen

Publication type:

Article

Causal associations between dietary habits and liver cancer risk: a two-sample Mendelian randomization study.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01885-w

By:

Hu, Wen-Hao;
Sun, Jia-An;
Liu, Chang

Publication type:

Article

Investigating causal relationship among inflammatory cytokines and oropharyngeal cancer: Mendelian randomization.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01809-8

By:

Xu, Sibo;
Li, Yiguo;
Chen, Wei;
Wang, Ke

Publication type:

Article

Causal role of ischemic heart disease in ovarian cancer subtypes.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01824-9

By:

Chen, Jianhai;
He, Huabin;
Gao, Ling

Publication type:

Article

Mutual causal effects between immune cells and hepatocellular carcinoma: a Mendelian randomization study.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01785-z

By:

Wang, Zheng;
Pan, Mengshu;
Zhu, Jie;
Liu, Changhong

Publication type:

Article

Elucidating stearoyl metabolism and NCOA4-mediated ferroptosis in gastric cancer liver metastasis through multi-omics single-cell integrative mendelian analysis: advancing personalized immunotherapy strategies.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01769-z

By:

Yang, Zhongqiu;
Chen, Yuquan;
Miao, Yaping;
Yan, Haisheng;
Chen, Kexin;
Xu, Yaoqin;
Su, Lanqian;
Zhang, Lanyue;
Yan, Yalan;
Chi, Hao;
Fu, Jin;
Wang, Lexin

Publication type:

Article

The role of histone lactylation genes in hepatocellular carcinoma prognostic models and their immune cell infiltration features: a comprehensive analysis of single-cell, spatial transcriptome, Mendelian randomization and experiment.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01775-1

By:

Luan, Shanjie

Publication type:

Article

Causal associations between circulating protein ratios and drug resistance in papillary thyroid cancer: a Mendelian randomization study.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01758-2

By:

Deng, Jiaqin;
Yu, Ming;
Gu, Yihua;
Lai, Yeqian;
Qiu, Lihong

Publication type:

Article

Identification of biomarkers for chronic lymphocytic leukemia risk: a proteome-wide Mendelian randomization study.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-024-01699-2

By:

Jin, Changyu;
Lu, Zehong;
Chen, Yuzhan;
Hu, Huijie;
Zhou, Miao;
Zhang, Yanli;
Ouyang, Guifang;
Li, Tongyu;
Sheng, Lixia

Publication type:

Article

Relationships between blood cadmium concentration and risk of nine cancers: evidence from the NHANES 1999–2018 and Mendelian randomization analyses.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01692-9

By:

Wang, Jiang;
Deng, Sijia;
Cheng, Guangyi;
Wang, Yuyan;
Shen, Yu;
Chen, Jiayi;
Xu, Ke;
Wang, Bo;
Han, Shuguang;
Li, Liantao

Publication type:

Article

Assessing the causality between pulmonary arterial hypertension and cancer: insights from Mendelian randomization.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01727-1

By:

Fu, Yang;
Duan, Xinwang;
Zhou, Wei

Publication type:

Article