Works matching DE "LIGANDS (Biochemistry)"

Results: 5000

Targeted protein degradation by KLHDC2 ligands identified by high-throughput screening.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.106844

By:

Han Zhou;
Tonglian Zhou;
Wenli Yu;
Liping Liu;
Yeonjin Ko;
Johnson, Kristen A.;
Wilson, Ian A.;
Schultz, Peter G.;
Bollong, Michael J.

Publication type:

Article

Targeted in vitro and in silico assessment of Moringa oleifera leaf extract: inhibitory effects on adipogenesis and enhancement of insulin sensitivity.

Published in:

3 Biotech, 2025, v. 15, n. 8, p. 1, doi. 10.1007/s13205-025-04395-2

By:

Kumar, K. B. Vijendra;
Mohan, Nikhil;
Singh, Khushboo;
Paul, Athul;
Nithyamol, K. V.;
Ramakrishnan, Shyam;
Varadaraju, Kavitha Raj

Publication type:

Article

Rational development of FMN-based orthogonal riboswitch that functions in response to specific non-cognate ligand.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60722-4

By:

Ojha, Divya;
Rode, Ambadas B.

Publication type:

Article

Catalytic asymmetric intermolecular [4 + 2] annulation of benzocyclobutenones with Alkynes and activated carbonyls via C—C activation.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60109-5

By:

Liu, Huilai;
Qi, Zisong;
Shi, Yue;
Wang, Wei;
Wang, Fen;
Ding, Zhi-Wen;
Jia, Ai-Qun;
Huang, Genping;
Li, Xingwei

Publication type:

Article

Recent Advances in Management of Vitiligo.

Published in:

Indian Journal of Dermatology, 2025, v. 70, n. 4, p. 201, doi. 10.4103/ijd.ijd_158_25

By:

Das, Kinnor;
Sarkar, Rashmi;
Sinha, Surabhi

Publication type:

Article

Enhanced Anticancer Activity of Novel Bi (III)‐Thiosemicarbazone Complexes Against Lung Cancer.

Published in:

Applied Organometallic Chemistry, 2025, v. 39, n. 7, p. 1, doi. 10.1002/aoc.70249

By:

Liu, Conghao;
Yang, Yang;
Li, Runzhi;
Zhang, Xiaoqing;
Silva, Dionisio Zaldivar;
Zhao, Yuefeng;
Ouyang, Ruizhuo;
Miao, Yuqing;
Liu, Baolin;
Zhou, Shuang

Publication type:

Article

Design and Synthesis of E7820/Tasisulam Hybrids as Potential DCAF15 Binders.

Published in:

Reactions (2624-781X), 2025, v. 6, n. 2, p. 34, doi. 10.3390/reactions6020034

By:

Hocine, Sofiane;
Cosson, Victor;
Calandrino, Remi;
Baló, Timea;
Bordelo, Jayson Alves;
Triboulet, Sébastien;
Caruana, Laure;
Klipfel, Laurence;
Calis, Sandrine;
Herner, András;
Hanessian, Stephen

Publication type:

Article

Structure–activity relationship of <sup>18</sup>F-labeled PD-L1-targeting small molecule ligands: impact of radiolabeling strategy on affinity and in vivo performance.

Published in:

EJNMMI Radiopharmacy & Chemistry, 2025, v. 10, n. 1, p. 1, doi. 10.1186/s41181-025-00359-2

By:

Krutzek, Fabian;
Donat, Cornelius K.;
Stadlbauer, Sven

Publication type:

Article

Design, Synthesis, and Application of a Family of Chiral Non‐C<sub>2</sub>‐Symmetric NHCs with a Fused Sidechain.

Published in:

Angewandte Chemie, 2025, v. 137, n. 27, p. 1, doi. 10.1002/ange.202508572

By:

Cai, Zhen‐Xi;
Zhang, Qi;
Wei, Tian‐Yu;
Tian, Hu;
Jiang, Jia‐Wei;
Wei, Zhang‐Yi;
Yin, Liang

Publication type:

Article

Ultrabright and Water‐Stable Eu(III)‐Based MOF Scintillators Sensitized by Dual‐Antenna Ligands for Real‐Time and Underwater X‐Ray Imaging.

Published in:

Angewandte Chemie, 2025, v. 137, n. 27, p. 1, doi. 10.1002/ange.202506118

By:

Chen, Hongming;
Yang, Xi;
Ye, Yuanji;
Hong, HongYang;
Wei, Qingsong;
Zhu, Yanan;
Lin, Mei‐Jin

Publication type:

Article

DNA Binding with Dipyrromethene Ruthenium(II) Complexes.

Published in:

Inorganics, 2025, v. 13, n. 6, p. 198, doi. 10.3390/inorganics13060198

By:

Murillo, Maria Isabel;
Mejia, Carlos Felipe;
Restrepo-Acevedo, Andrés;
Barraud, Benjamin;
Orjuela, Adrian L.;
Flores-Alamo, Marcos;
Toscano, Rubén A.;
Alí-Torres, Jorge;
Ryabov, Alexander D.;
Le Lagadec, Ronan

Publication type:

Article

Ginsenosides as Potential Natural Ligands of SLC3A2: Computational Insights in Cancer.

Published in:

Life (2075-1729), 2025, v. 15, n. 6, p. 907, doi. 10.3390/life15060907

By:

Lu, Jing

Publication type:

Article

Accurate Prediction of Drug Activity by Computational Methods: Importance of Thermal Capacity.

Published in:

Molecules, 2025, v. 30, n. 12, p. 2563, doi. 10.3390/molecules30122563

By:

Palese, Luigi Leonardo

Publication type:

Article

Transcriptome-Wide Identification of Neuropeptides and Neuropeptide Receptors in the Twenty-Eight-Spotted Ladybird Henosepilachna vigintioctopunctata.

Published in:

Insects (2075-4450), 2025, v. 16, n. 6, p. 624, doi. 10.3390/insects16060624

By:

Lei, Quanxing;
Wang, Ziming;
Yao, Shuangyan;
Lin, Aili;
Zhang, Yunhui;
Sun, Chengxian;
Liu, Xiaoguang;
Du, Mengfang;
Liu, Xiaoming;
An, Shiheng

Publication type:

Article

Comprehensive Analysis of the UGT Gene Superfamily in Spodoptera frugiperda.

Published in:

Insects (2075-4450), 2025, v. 16, n. 6, p. 601, doi. 10.3390/insects16060601

By:

Liu, Yang;
Guan, Minghui;
Zou, Kunliang;
Wang, Tonghan;
Wang, Haiyang;
Sun, Lu;
Feng, Bo;
Ding, Jiali;
Gao, Xiang;
Wang, Yongfu;
Wu, Degong;
Du, Junli

Publication type:

Article

New Nitrogen-, Oxygen-, and Sulfur-Containing Heterocyclic Compounds as Anti-Colon Cancer Agents: Synthesis, Multitargeted Evaluations, Molecular Docking Simulations and ADMET Predictions.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 801, doi. 10.3390/ph18060801

By:

El-Sayed, Nahed Nasser Eid;
Krayem, Najeh;
Derbala, Hamed Ahmed;
Kamal, Shimaa;
Bukhari, Syde Nasir Abbas;
El-Ashrey, Mohamed K.;
Almarhoon, Zainab M.;
Soliman Alterary, Seham;
Ben Bacha, Abir

Publication type:

Article

Nörosteroidler: Psikofarmakolojik ve Davranışsal Etkileri.

Published in:

Klinik Psikofarmakoloji Bulteni, 2004, v. 14, n. 1, p. 38

By:

Kartalci, Şükrü;
Eşel, Ertuğrul

Publication type:

Article

Immune evasion: UL141 keeps HCMV in charge.

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 5, p. 297, doi. 10.1038/nrmicro3018

By:

David, Rachel

Publication type:

Article

Parasitology: Leishmania turns down the heat.

Published in:

Nature Reviews Microbiology, 2011, v. 9, n. 8, p. 560, doi. 10.1038/nrmicro2626

By:

Huddleston, Joanna E.

Publication type:

Article

Signature Patterns of MHC Diversity in Three Gombe Communities of Wild Chimpanzees Reflect Fitness in Reproduction and Immune Defense against SIVcpz.

Published in:

PLoS Biology, 2015, v. 13, n. 5, p. 1, doi. 10.1371/journal.pbio.1002144

By:

Wroblewski, Emily E.;
Norman, Paul J.;
Guethlein, Lisbeth A.;
Rudicell, Rebecca S.;
Ramirez, Miguel A.;
Li, Yingying;
Hahn, Beatrice H.;
Pusey, Anne E.;
Parham, Peter

Publication type:

Article

Site-Directed Spin Labeling Reveals Pentameric Ligand-Gated Ion Channel Gating Motions.

Published in:

PLoS Biology, 2013, v. 11, n. 11, p. 1, doi. 10.1371/journal.pbio.1001714

By:

Dellisanti, Cosma D.;
Ghosh, Borna;
Hanson, Susan M.;
Raspanti, James M.;
Grant, Valerie A.;
Diarra, Gaoussou M.;
Schuh, Abby M.;
Satyshur, Kenneth;
Klug, Candice S.;
Czajkowski, Cynthia

Publication type:

Article

Steroids as Central Regulators of Organismal Development and Lifespan.

Published in:

PLoS Biology, 2012, v. 10, n. 4, p. 1, doi. 10.1371/journal.pbio.1001307

By:

Lee, Siu Sylvia;
Schroeder, Frank C.

Publication type:

Article

Binding of Superantigen Toxins into the CD28 Homodimer Interface Is Essential for Induction of Cytokine Genes That Mediate Lethal Shock.

Published in:

PLoS Biology, 2011, v. 9, n. 9, p. 1, doi. 10.1371/journal.pbio.1001149

By:

Arad, Gila;
Levy, Revital;
Nasie, Iris;
Hillman, Dalia;
Rotfogel, Ziv;
Barash, Uri;
Supper, Emmanuelle;
Shpilka, Tomer;
Minis, Adi;
Kaempfer, Raymond

Publication type:

Article

Ligand Activation of the Prokaryotic Pentameric Ligand- Gated Ion Channel ELIC.

Published in:

PLoS Biology, 2011, v. 9, n. 6, p. 1, doi. 10.1371/journal.pbio.1001101

By:

Zimmermann, Iwan;
Dutzler, Raimund

Publication type:

Article

The Naturally Processed CD95L Elicits a c-Yes/Calcium/ PI3K-Driven Cell Migration Pathway.

Published in:

PLoS Biology, 2011, v. 9, n. 6, p. 1, doi. 10.1371/journal.pbio.1001090

By:

Tauzin, Sébastien;
Chaigne-Delalande, Benjamin;
Selva, Eric;
Khadra, Nadine;
Daburon, Sophie;
Contin-Bordes, Cécile;
Blanco, Patrick;
Seyec, Jacques Le;
Ducret, Thomas;
Counillon, Laurent;
Moreau, Jean-François;
Hofman, Paul;
Vacher, Pierre;
Legembre, Patrick

Publication type:

Article

A Structural and Mutagenic Blueprint for Molecular Recognition of Strychnine and d-Tubocurarine by Different Cys-Loop Receptors.

Published in:

PLoS Biology, 2011, v. 9, n. 3, p. 1, doi. 10.1371/journal.pbio.1001034

By:

Brams, Marijke;
Pandya, Anshul;
Kuzmin, Dmitry;
Elk, Renévan;
Krijnen, Liz;
Yakel, Jerrel L.;
Tsetlin, Victor;
Smit, August B.;
Ulens, Chris

Publication type:

Article

EphrinB/EphB Signaling Controls Embryonic Germ Layer Separation by Contact-Induced Cell Detachment.

Published in:

PLoS Biology, 2011, v. 9, n. 3, p. 1, doi. 10.1371/journal.pbio.1000597

By:

Rohani, Nazanin;
Canty, Laura;
Luu, Olivia;
Fagotto, François;
Winklbauer, Rudolf

Publication type:

Article

Prox1 Regulates the Notch1-Mediated Inhibition of Neurogenesis.

Published in:

PLoS Biology, 2010, v. 8, n. 12, p. 1, doi. 10.1371/journal.pbio.1000565

By:

Kaltezioti, Valeria;
Kouroupi, Georgia;
Oikonomaki, Maria;
Mantouvalou, Evangelia;
Stergiopoulos, Athanasios;
Charonis, Aristidis;
Rohrer, Hermann;
Matsas, Rebecca;
Politis, Panagiotis K.

Publication type:

Article

HER2 Phosphorylation Is Maintained by a PKB Negative Feedback Loop in Response to Anti-HER2 Herceptin in Breast Cancer.

Published in:

PLoS Biology, 2010, v. 8, n. 12, p. 1, doi. 10.1371/journal.pbio.1000563

By:

Gijsen, Merel;
King, Peter;
Perera, Tim;
Parker, Peter J.;
Harris, Adrian L.;
Larijani, Banafshé;
Kong, Anthony

Publication type:

Article

Structure of a Classical MHC Class I Molecule That Binds ''Non-Classical'' Ligands.

Published in:

PLoS Biology, 2010, v. 8, n. 12, p. 1, doi. 10.1371/journal.pbio.1000557

By:

Chee Seng Hee;
Song Gao;
Loll, Bernhard;
Miller, Marcia M.;
Uchanska-Ziegler, Barbara;
Daumke, Oliver;
Ziegler, Andreas

Publication type:

Article

Structural and Biochemical Characterization of the Human Cyclophilin Family of Peptidyl-Prolyl Isomerases.

Published in:

PLoS Biology, 2010, v. 8, n. 7, p. 1, doi. 10.1371/journal.pbio.1000439

By:

Davis, Tara L.;
Walker, John R.;
Campagna-Slater, Valérie;
Finerty Jr., Patrick J.;
Paramanathan, Ragika;
Bernstein, Galina;
MacKenzie, Farrell;
Tempel, Wolfram;
Hui Ouyang;
Wen Hwa Lee;
Eisenmesser, Elan Z.;
Dhe-Paganon, Sirano

Publication type:

Article

Voltage-Dependent Gating in a "Voltage Sensor-Less" Ion Channel.

Published in:

PLoS Biology, 2010, v. 8, n. 2, p. 1, doi. 10.1371/journal.pbio.1000315

By:

Kurata, Harley T.;
Rapedius, Markus;
Kleinman, Marc J.;
Baukrowitz, Thomas;
Nichols, Colin G.

Publication type:

Article

Current Affairs: A Mutation's-Eye View of Voltage Gating.

Published in:

PLoS Biology, 2010, v. 8, n. 2, p. 1, doi. 10.1371/journal.pbio.1000314

By:

Hoff, Mary

Publication type:

Article

Recognition of Lyso-Phospholipids by Human Natural Killer T Lymphocytes.

Published in:

PLoS Biology, 2009, v. 7, n. 10, p. 1, doi. 10.1371/journal.pbio.1000228

By:

Fox, Lisa M.;
Cox, Daryl G.;
Lockridge, Jennifer L.;
Xiaohua Wang;
Xiuxu Chen;
Scharf, Louise;
Trott, David L.;
Ndonye, Rachel M.;
Veerapen, Natacha;
Besra, Gurdyal S.;
Howell, Amy R.;
Cook, Mark E.;
Adams, Erin J.;
Hildebrand, William H.;
Gumperz, Jenny E.

Publication type:

Article

Cytoplasmic Relaxation of Active Eph Controls Ephrin Shedding by ADAM10.

Published in:

PLoS Biology, 2009, v. 7, n. 10, p. 1, doi. 10.1371/journal.pbio.1000215

By:

Janes, Peter W.;
Wimmer-Kleikamp, Sabine H.;
Frangakis, Achilleas S.;
Treble, Kane;
Griesshaber, Bettina;
Sabet, Ola;
Grabenbauer, Markus;
Ting, Alice Y.;
Saftig, Paul;
Bastiaens, Philippe I.;
Lackmann, Martin

Publication type:

Article

Ligand-Independent Traffic of Notch Buffers Activated Armadillo in Drosophila.

Published in:

PLoS Biology, 2009, v. 7, n. 8, p. 1, doi. 10.1371/journal.pbio.1000169

By:

Sanders, Phil G. T.;
Muñoz-Descalzo, Silvia;
Balayo, Tina;
Wirtz-Peitz, Frederik;
Hayward, Penelope;
Arias, Alfonso Martinez

Publication type:

Article

The Structural Basis of Gas-Responsive Transcription by the Human Nuclear Hormone Receptor REV-ERB.

Published in:

PLoS Biology, 2009, v. 7, n. 2, p. e1000043, doi. 10.1371/journal.pbio.1000043

By:

Pardee, Keith I.;
Xu, Xiaohui;
Reinking, Jeff;
Schuetz, Anja;
Dong, Aiping;
Liu, Suya;
Zhang, Rongguang;
Tiefenbach, Jens;
Lajoie, Gilles;
Plotnikov, Alexander N.;
Botchkarev, Alexey;
Krause, Henry M.;
Edwards, Aled

Publication type:

Article

Modeling a Snap-Action, Variable-Delay Switch Controlling Extrinsic Cell Death.

Published in:

PLoS Biology, 2008, v. 6, n. 12, p. e299, doi. 10.1371/journal.pbio.0060299

By:

Albeck, John G.;
Burke, John M.;
Spencer, Sabrina L.;
Lauffenburger, Douglas A.;
Sorger, Peter K.

Publication type:

Article

A Specificity Map for the PDZ Domain Family.

Published in:

PLoS Biology, 2008, v. 6, n. 9, p. e239, doi. 10.1371/journal.pbio.0060239

By:

Sazinsky, Stephen L.;
Currell, Bridget;
Jung-Hua Yeh;
Reva, Boris;
Held, Heike A.;
Appleton, Brent A.;
Evangelista, Marie;
Yan Wu;
Xiaofeng Xin;
Chan, Andrew C.;
Seshagiri, Somasekar;
Lasky, Laurence A.;
Sander, Chris;
Boone, Charles;
Bader, Gary D.;
Sidhu, Sachdev S.

Publication type:

Article

OSM-11 Facilitates LIN-12 Notch Signaling during Caenorhabditis elegans Vulval Development.

Published in:

PLoS Biology, 2008, v. 6, n. 8, p. e196, doi. 10.1371/journal.pbio.0060196

By:

komatsu, Hidetoshi;
Chao, Michael Y.;
Larkins-Ford, Jonah;
Corkins, Mark E.;
Somers, Gerard A.;
Tucey, Tim;
Dionne, Heather M.;
White, Jaime Q.;
Wani, Kursheed;
Boxem, Mike;
Hart, Anne C.

Publication type:

Article

Selective Ligand Recognition by a Diversity-Generating Retroelement Variable Protein.

Published in:

PLoS Biology, 2008, v. 6, n. 6, p. e131, doi. 10.1371/journal.pbio.0060131

By:

Miller, Jason L.;
Le Coq, Johanne;
Hodes, Asher;
Barbalat, Roman;
Miller, Jeff F.;
Ghosh, Partho

Publication type:

Article

Hox Paralog Group 2 Genes Control the Migration of Mouse Pontine Neurons through Slit-Robo Signaling.

Published in:

PLoS Biology, 2008, v. 6, n. 6, p. e142, doi. 10.1371/journal.pbio.0060142

By:

Geisen, Marc J.;
Di Meglio, Thomas;
Pasqualetti, Massimo;
Ducret, Sebastien;
Brunet, Jean-Franois;
Chedotal, Alain;
Rijli, Filippo M.

Publication type:

Article

Resolving the Fast Kinetics of Cooperative Binding: Ca2+ Buffering by Calretinin.

Published in:

PLoS Biology, 2007, v. 5, n. 11, p. e311, doi. 10.1371/journal.pbio.0050311

By:

Faas, Guido C.;
Schwaller, Beat;
Vergara, Julio L.;
Mody, Istvan

Publication type:

Article

B Cell Antigen Receptor Signaling and Internalization Are Mutually Exclusive Events.

Published in:

PLoS Biology, 2006, v. 4, n. 7, p. e200, doi. 10.1371/journal.pbio.0040200

By:

Ping Hou;
Araujo, Elizabeth;
Tong Zhao;
Miao Zhang;
Massenburg, Don;
Veselits, Margaret;
Doyle, Colleen;
Dinner, Aaron R.;
Clark, Marcus R.

Publication type:

Article

Correction: Human MicroRNA Targets.

Published in:

2005

By:

John, Bino;
Enright, Anton J;
Aravin, Alexei;
Tuschl, Thomas;
Sander, Chris;
Marks, Debora S

Publication type:

Correction Notice

Neutralizing Aptamers from Whole-Cell SELEX Inhibit the RET Receptor Tyrosine Kinase.

Published in:

PLoS Biology, 2005, v. 3, n. 4, p. 697, doi. 10.1371/journal.pbio.0030123

By:

Cerchia, Laura;
Ducongé, Frédéric;
Pestourie, Carine;
Boulay, Jocelyne;
Aissouni, Youssef;
Gombert, Karine;
Tavitian, Bertrand;
Franciscis, Vittorio de;
Libri, Domenico

Publication type:

Article

Crucial Roles in Drosophila Development for Little-Known Protein.

Published in:

PLoS Biology, 2005, v. 3, n. 4, p. 548, doi. 10.1371/journal.pbio.0030139

By:

Le Borgne, R.;
Remaud, S.;
Hamel, S.;
Lai, E. C.;
Schweisguth, F.

Publication type:

Article

When It Comes to Frizzled-Mediated Developmental Pathways, Location Matters.

Published in:

PLoS Biology, 2004, v. 2, n. 7, p. 7, doi. 10.1371/journal.pbio.0020205

By:

Wu, J;
Klein, TJ

Publication type:

Article

JAMM: A Metalloprotease-Like Zinc Site in the Proteasome and Signalosome.

Published in:

PLoS Biology, 2004, v. 2, n. 1, p. 0001, doi. 10.1371/journal/pbio.0020002

By:

Ambroggio, Xavier I.;
Rees, Douglas C.;
Deshaies, Raymond J.;
Ploegh, Hidde L.

Publication type:

Article

Antigen-Specific T Cells: Analyses of the Needles in the Haystack.

Published in:

PLoS Biology, 2003, v. 1, n. 3, p. 329, doi. 10.1371/journal.pbio.0000078

By:

Slansky, Jill E.

Publication type:

Article