Works about LIGAND-gated ion channels

Results: 313

The Dysregulation of Tuning Receptors and Transcription Factors in the Antennae of Orco and Ir8a Mutants in Aedes aegypti Suggests a Chemoreceptor Regulatory Mechanism Involving the MMB/dREAM Complex.

Published in:

Insects (2075-4450), 2025, v. 16, n. 6, p. 638, doi. 10.3390/insects16060638

By:

Cooke, Matthew M.;
Chembars II, Michael S.;
Pitts, Ronald Jason

Publication type:

Article

Conformational Transitions and Allosteric Modulation in a Heteromeric Glycine Receptor.

Published in:

Microscopy & Microanalysis, 2024, v. 30, p. 1, doi. 10.1093/mam/ozae044.366

By:

Gibbs, Eric;
Klemm, Emily;
Seiferth, David;
Kumar, Arvind;
Ilca, Serban L;
Biggin, Philip C;
Chakrapani, Sudha

Publication type:

Article

Nonsynonymous variations of ion channel-related genes as risk factors in epilepsy.

Published in:

Journal of Experimental & Clinical Medicine / Deneysel ve Klinik Tip Dergisi, 2021, v. 38, n. 3, p. 288, doi. 10.52142/omujecm.38.3.15

By:

SÜT, Burcu BİTERGE;
SOYTÜRK, Hayriye

Publication type:

Article

Discovery of lipid binding sites in a ligand-gated ion channel by integrating simulations and cryo-EM.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.86016

By:

Bergh, Cathrine;
Rovšnik, Urška;
Howard, Rebecca;
Lindahl, Erik

Publication type:

Article

Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.86029

By:

De Gieter, Steven;
Gallagher, Casey I.;
Wijckmans, Eveline;
Pasini, Diletta;
Ulens, Chris;
Efremov, Rouslan G.

Publication type:

Article

Allosteric modulation and direct activation of glycine receptors by a tricyclic sulfonamide.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-90209-7

By:

Lara, César O.;
Burgos, Carlos F.;
Fariña-Oliva, Katherine;
Marileo, Ana M.;
Martín, Victoria P. San;
Flaig, David;
Soto-Ortega, Paul;
Contreras, Omayra V.;
Sazo, Anggelo;
Gaete-Riquelme, Krishna;
Corradi, Jeremías;
Muñoz-Montesino, Carola;
Fuentealba, Jorge;
Castro, Patricio A.;
Aguayo, Luis G.;
Bouzat, Cecilia;
Moraga-Cid, Gustavo;
Yévenes, Gonzalo E.

Publication type:

Article

Inhibition of NMDA receptors and other ion channel types by membrane-associated drugs.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1561956

By:

Neureiter, Elizabeth G.;
Erickson-Oberg, M. Quincy;
Nigam, Aparna;
Johnson, Jon W.

Publication type:

Article

Cellular and Molecular Targets of Menthol Actions.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00472

By:

Oz, Murat;
El Nebrisi, Eslam G.;
Yang, Keun-Hang S.;
Howarth, Frank C.;
Al Kury, Lina T.

Publication type:

Article

Activated P2X receptors can up-regulate the expressions of inflammation-related genes via NF-κB pathway in spotted sea bass (Lateolabrax maculatus).

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1181067

By:

Zhaosheng Sun;
Qian Gao;
Youchuan Wei;
Zhigang Zhou;
Yuxi Chen;
Chong Xu;
Jiaqi Gao;
Danjie Liu

Publication type:

Article

µ-Opioid receptor activation by tramadol and O-desmethyltramadol (M1).

Published in:

Journal of Anesthesia, 2015, v. 29, n. 3, p. 475, doi. 10.1007/s00540-014-1946-z

By:

Minami, Kouichiro;
Sudo, Yuka;
Miyano, Kanako;
Murphy, Robert;
Uezono, Yasuhito

Publication type:

Article

Assessment and Management of Cough in Idiopathic Pulmonary Fibrosis: A Narrative Review.

Published in:

Lung (0341-2040), 2023, v. 201, n. 6, p. 531, doi. 10.1007/s00408-023-00653-3

By:

Liu, Shangxiang;
Ye, Xu

Publication type:

Article

Coming Soon: The First-Ever Drug(s) for Refractory Chronic Cough.

Published in:

2021

By:

Dicpinigaitis, Peter V.

Publication type:

Editorial

Trapping of spermine, Kukoamine A, and polyamine toxin blockers in GluK2 kainate receptor channels.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-54538-x

By:

Gangwar, Shanti Pal;
Yelshanskaya, Maria V.;
Aktolun, Muhammed;
Yen, Laura Y.;
Newton, Thomas P.;
Strømgaard, Kristian;
Kurnikova, Maria G.;
Sobolevsky, Alexander I.

Publication type:

Article

Symmetry-adapted Markov state models of closing, opening, and desensitizing in α 7 nicotinic acetylcholine receptors.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53170-z

By:

Zhuang, Yuxuan;
Howard, Rebecca J.;
Lindahl, Erik

Publication type:

Article

Structural insights into the human P2X1 receptor and ligand interactions.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52776-7

By:

Bennetts, Felix M.;
Venugopal, Hariprasad;
Glukhova, Alisa;
Mobbs, Jesse I.;
Ventura, Sabatino;
Thal, David M.

Publication type:

Article

Finely ordered intracellular domain harbors an allosteric site to modulate physiopathological function of P2X3 receptors.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51815-7

By:

Lin, Yi-Yu;
Lu, Yan;
Li, Chun-Yun;
Ma, Xue-Fei;
Shao, Miao-Qing;
Gao, Yu-Hao;
Zhang, Yu-Qing;
Jiang, Hai-Ning;
Liu, Yan;
Yang, Yang;
Huang, Li-Dong;
Cao, Peng;
Wang, Heng-Shan;
Wang, Jin;
Yu, Ye

Publication type:

Article

Anesthetic Potential of Herbal Plants.

Published in:

International Journal of Pharmacy & Life Sciences, 2020, v. 11, n. 7, p. 69

By:

Sontakke, Rupali;
Singhal, Rohit;
Jain, Neetesh Kumar

Publication type:

Article

Anesthetic Potential of Herbal Plants.

Published in:

International Journal of Pharmacy & Life Sciences, 2020, v. 11, n. 6, p. 69

By:

Sontakke, Rupali;
Singhal, Rohit;
Jain, Neetesh Kumar

Publication type:

Article

A Study on the Effect of Putrescine on MES and Chemical Induced Convulsions in Mice.

Published in:

International Journal of Pharmacy & Life Sciences, 2015, v. 6, n. 6, p. 4573

By:

Khan, Firdos;
Kukde, Deepshikha;
Zaveri, Purvi;
Mohsina, Sayyed;
Sharma, Vimukta

Publication type:

Article

Transient forebrain ischemia under hyperthermic condition accelerates memory impairment and neuronal death in the gerbil hippocampus by increasing NMDAR1 expression.

Published in:

Molecular Medicine Reports, 2021, v. 23, n. 4, p. N.PAG, doi. 10.3892/mmr.2021.11895

By:

Kim, Bora;
Ahn, Ji Hyeon;
Kim, Dae Won;
Lee, Tae-Kyeong;
Kim, Yoon Sung;
Shin, Myoung Cheol;
Cho, Jun Hwi;
Kim, Young-Myeong;
Park, Joon Ha;
Kang, Il Jun;
Lee, Jae-Chul;
Won, Moo-Ho

Publication type:

Article

Conditional permeabilization of the P. falciparum plasma membrane in infected cells links cation influx to reduced membrane integrity.

Published in:

PLoS ONE, 2023, v. 18, n. 4, p. 1, doi. 10.1371/journal.pone.0283776

By:

Sylla, Mariame;
Gupta, Ankit;
Shao, Jinfeng;
Desai, Sanjay A.

Publication type:

Article

Editorial: Targeting ion channels for drug discovery: emerging challenges for high throughput screening technologies.

Published in:

Frontiers in Molecular Neuroscience, 2024, p. 01, doi. 10.3389/fnmol.2024.1414816

By:

Hernandez, Ciria C.;
Gimenez, Luis E.;
Strassmaier, Tim;
Rogers, Marc;
Taymans, Jean-Marc

Publication type:

Article

Molecular Mechanisms of Glutamate Toxicity in Parkinson's Disease.

Published in:

Frontiers in Neuroscience, 2020, v. 14, p. N.PAG, doi. 10.3389/fnins.2020.585584

By:

Wang, Ji;
Wang, Fushun;
Mai, Dongmei;
Qu, Shaogang

Publication type:

Article

Structure-Function of Neuronal Nicotinic Acetylcholine Receptor Inhibitors Derived From Natural Toxins.

Published in:

Frontiers in Neuroscience, 2020, v. 14, p. N.PAG, doi. 10.3389/fnins.2020.609005

By:

Ho, Thao N. T.;
Abraham, Nikita;
Lewis, Richard J.

Publication type:

Article

A New Mechanism of Receptor Targeting by Interaction between Two Classes of Ligand-Gated Ion Channels.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 5, p. 1456, doi. 10.1523/JNEUROSCI.2390-15.2016

By:

Emerit, Michel Boris;
Baranowski, Camille;
Diaz, Jorge;
Martinez, Audrey;
Areias, Julie;
Alterio, Jeanine;
Masson, Justine;
Boué-Grabot, Eric;
Darmon, Michèle

Publication type:

Article

Unraveling Mechanisms Underlying Partial Agonism in 5-HT3A Receptors.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 50, p. 16865, doi. 10.1523/JNEUROSCI.1970-14.2014

By:

Corradi, Jeremías;
Bouzat, Cecilia

Publication type:

Article

Controlling NMDA Receptor Subunit Composition Using Ectopic Retention Signals.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 50, p. 16630, doi. 10.1523/JNEUROSCI.2736-14.2014

By:

Stroebel, David;
Carvalho, Stéphanie;
Grand, Teddy;
Shujia Zhu;
Paoletti, Pierre

Publication type:

Article

Compartment-Specific Modulation of GABAergic Synaptic Transmission by TRPV1 Channels in the Dentate Gyrus.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 50, p. 16621, doi. 10.1523/JNEUROSCI.3635-14.2014

By:

Chávez, Andrés E.;
Hernández, Vivian M.;
Rodenas-Ruano, Alma;
Chan, C. Savio;
Castillo, Pablo E.

Publication type:

Article

A Lipid Gate for the Peripheral Control of Pain.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 46, p. 15184, doi. 10.1523/JNEUROSCI.3475-14.2014

By:

Piomelli, Daniele;
Hohmann, Andrea G.;
Seybold, Virginia;
Hammock, Bruce D.

Publication type:

Article

More Than a Pore: Ion Channel Signaling Complexes.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 46, p. 15159, doi. 10.1523/JNEUROSCI.3275-14.2014

By:

Lee, Amy;
Fakler, Bernd;
Kaczmarek, Leonard K.;
Isom, Lori L.

Publication type:

Article

Fast Phasic Release Properties of Dopamine Studied with a Channel Biosensor.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 35, p. 11792, doi. 10.1523/JNEUROSCI.2355-14.2014

By:

Kress, Geraldine J.;
Hong-Jin Shu;
Yu, Andrew;
Taylor, Amanda;
Benz, Ann;
Harmon, Steve;
Mennerick, Steven

Publication type:

Article

Ivermectin: a mini-review.

Published in:

Clinical Toxicology (15563650), 2022, v. 60, n. 5, p. 571, doi. 10.1080/15563650.2022.2043338

By:

Johnson-Arbor, Kelly

Publication type:

Article

Is the antiparasitic drug ivermectin a suitable candidate for the treatment of epilepsy?

Published in:

Epilepsia (Series 4), 2023, v. 64, n. 3, p. 553, doi. 10.1111/epi.17511

By:

Löscher, Wolfgang

Publication type:

Article

Brivaracetam does not modulate ionotropic channels activated by glutamate, γ-aminobutyric acid, and glycine in hippocampal neurons.

Published in:

Epilepsia (Series 4), 2017, v. 58, n. 11, p. e157, doi. 10.1111/epi.13890

By:

Niespodziany, Isabelle;
Rigo, Jean ‐ Michel;
Moonen, Gustave;
Matagne, Alain;
Klitgaard, Henrik;
Wolff, Christian

Publication type:

Article

Lighting Up the Plasma Membrane: Development and Applications of Fluorescent Ligands for Transmembrane Proteins.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 34, p. 8605, doi. 10.1002/chem.202100296

By:

Borgarelli, Carlotta;
Klingl, Yvonne E.;
Escamilla‐Ayala, Abril;
Munck, Sebastian;
Van Den Bosch, Ludo;
De Borggraeve, Wim M.;
Ismalaj, Ermal

Publication type:

Article

Unravelling the Turn‐On Fluorescence Mechanism of a Fluorescein‐Based Probe in GABAA Receptors.

Published in:

Angewandte Chemie, 2022, v. 134, n. 30, p. 1, doi. 10.1002/ange.202205198

By:

Singer, Nadja K.;
Sánchez‐Murcia, Pedro A.;
Ernst, Margot;
González, Leticia

Publication type:

Article

Reversible Ligand‐Gated Ion Channel via Interconversion between Hollow Single Helix and Intertwined Double Helix.

Published in:

Angewandte Chemie, 2020, v. 132, n. 32, p. 13704, doi. 10.1002/ange.201916755

By:

Bai, Dongya;
Yan, Tengfei;
Wang, Shi;
Wang, Yanbo;
Fu, Jiya;
Fang, Xiaomin;
Zhu, Junyan;
Liu, Junqiu

Publication type:

Article

Genome-wide analysis of glutamate receptor gene family in allopolyploid Brassica napus and its diploid progenitors.

Published in:

Genetica, 2023, v. 151, n. 4/5, p. 293, doi. 10.1007/s10709-023-00192-y

By:

Roy, Bidhan Chandra;
Shukla, Nikita;
Gachhui, Ratan;
Mukherjee, Ashutosh

Publication type:

Article

P2X7 receptor inhibition attenuates podocyte injury by oxLDL through deregulating CXCL16.

Published in:

Cell Biology International, 2022, v. 46, n. 3, p. 454, doi. 10.1002/cbin.11742

By:

Zhu, Yanji;
Li, Qian;
Chen, Yuan;
Tian, Minle;
Xun, Wenlong;
Sun, Shuzhen

Publication type:

Article

P2X receptors mediated abnormal interaction between satellite glial cells and neurons in visceral pathological changes.

Published in:

Cell Biology International, 2019, v. 43, n. 12, p. 1346, doi. 10.1002/cbin.11195

By:

Wang, Zilin;
Li, Lin;
Yang, Runan;
Xu, Xiumei;
Liang, Shangdong

Publication type:

Article

Enhancing effect of nicotine on electrical field stimulation elicited contractile responses in isolated rabbit bladder straight muscle; the role of cannabinoid and vanilloid receptors.

Published in:

Turkish Journal of Medical Sciences, 2022, v. 52, n. 6, p. 1814, doi. 10.55730/1300-0144.5527

By:

İLHAN, Sevil Özger;
Öztürk FİNCAN, Gökçe Sevim;
OKÇAY, Yağmur;
KOÇ, Derya Sebile;
AŞKIN, Celil İlker;
KİBAR, Ayşe Kübra;
VURAL, İsmail Mert;
SARIOĞLU, Yusuf

Publication type:

Article

Pathogenesis and Targeted Therapy of Epilepsy.

Published in:

Biomedicines, 2022, v. 10, n. 12, p. 3134, doi. 10.3390/biomedicines10123134

By:

N'Gouemo, Prosper

Publication type:

Article

UFR2709, an Antagonist of Nicotinic Acetylcholine Receptors, Delays the Acquisition and Reduces Long-Term Ethanol Intake in Alcohol-Preferring UChB Bibulous Rats.

Published in:

Biomedicines, 2022, v. 10, n. 7, p. N.PAG, doi. 10.3390/biomedicines10071482

By:

Gálvez, Gabriel;
González-Gutiérrez, Juan Pablo;
Hödar-Salazar, Martín;
Sotomayor-Zárate, Ramón;
Quintanilla, María Elena;
Quilaqueo, María Elena;
Rivera-Meza, Mario;
Iturriaga-Vásquez, Patricio

Publication type:

Article

MET Oncogene Enhances Pro-Migratory Functions by Counteracting NMDAR2B Cleavage.

Published in:

Cells (2073-4409), 2024, v. 13, n. 1, p. 28, doi. 10.3390/cells13010028

By:

Gallo, Simona;
Vitacolonna, Annapia;
Comoglio, Paolo Maria;
Crepaldi, Tiziana

Publication type:

Article

Two-Pore Channels Regulate Inter-Organellar Ca 2+ Homeostasis in Immune Cells.

Published in:

Cells (2073-4409), 2022, v. 11, n. 9, p. N.PAG, doi. 10.3390/cells11091465

By:

Steiner, Philip;
Arlt, Elisabeth;
Boekhoff, Ingrid;
Gudermann, Thomas;
Zierler, Susanna

Publication type:

Article

Deletion of P2X7 Receptor Decreases Basal Glutathione Level by Changing Glutamate-Glutamine Cycle and Neutral Amino Acid Transporters.

Published in:

Cells (2073-4409), 2020, v. 9, n. 4, p. 995, doi. 10.3390/cells9040995

By:

Park, Hana;
Kim, Ji-Eun

Publication type:

Article

The role of ion channels in microglial activation and proliferation -- a complex interplay between ligand-gated ion channels, K+ channels, and intracellular Ca2+.

Published in:

Frontiers in Immunology, 2015, v. 6, p. 1, doi. 10.3389/fimmu.2015.00497

By:

Stebbing, Martin James;
Cottee, Jennifer Marie;
Rana, Indrajeetsinh

Publication type:

Article

In vivo spatiotemporal control of voltage-gated ion channels by using photoactivatable peptidic toxins.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-27974-w

By:

Montnach, Jérôme;
Blömer, Laila Ananda;
Lopez, Ludivine;
Filipis, Luiza;
Meudal, Hervé;
Lafoux, Aude;
Nicolas, Sébastien;
Chu, Duong;
Caumes, Cécile;
Béroud, Rémy;
Jopling, Chris;
Bosmans, Frank;
Huchet, Corinne;
Landon, Céline;
Canepari, Marco;
De Waard, Michel

Publication type:

Article

The complexities of ligand/receptor interactions: Exploring the role of molecular vibrations and quantum tunnelling.

Published in:

BioEssays, 2024, v. 46, n. 5, p. 1, doi. 10.1002/bies.202300195

By:

Pagán, Oné R.

Publication type:

Article

Effects of cannabinoids on ligand-gated ion channels.

Published in:

Frontiers in Physiology, 2022, v. 13, p. 01, doi. 10.3389/fphys.2022.1041833

By:

Oz, Murat;
Yang, Keun-Hang Susan;
Mahgoub, Mohamed Omer

Publication type:

Article