Works about INVESTIGATIONAL therapies

Results: 1114

Editorial: Progress in neuroacanthocytosis syndromes and related diseases including other bulk lipid transfer disorders.

Published in:

2025

By:

Danek, Adrian;
Hermann, Andreas;
Kaestner, Lars;
Masana, Mercè;
Peikert, Kevin;
Rodriguez, Manuel J.;
Walker, Ruth H.

Publication type:

Editorial

Impacts and New Challenges with Highly Effective Modulator Therapies in Younger Children with Cystic Fibrosis.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 13, p. 4625, doi. 10.3390/jcm14134625

By:

Uyangoda, Kanchana;
Dawson, Charlotte;
Gudka, Nikesh;
Brugha, Rossa

Publication type:

Article

The Role of Somatic Mutation in Hereditary Hemorrhagic Telangiectasia Pathogenesis.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 13, p. 4479, doi. 10.3390/jcm14134479

By:

DeBose-Scarlett, Evon;
Marchuk, Douglas A.

Publication type:

Article

Sialylation as a checkpoint for inflammatory and complement-related retinal diseases.

Published in:

Frontiers in Cellular Neuroscience, 2025, p. 1, doi. 10.3389/fncel.2025.1623755

By:

Min, Yiduo;
Cuevas-Rios, German;
Langmann, Thomas;
Neumann, Harald

Publication type:

Article

Targeting Ocular Biofilms with Plant-Derived Antimicrobials in the Era of Antibiotic Resistance.

Published in:

Molecules, 2025, v. 30, n. 13, p. 2863, doi. 10.3390/molecules30132863

By:

Dzięgielewska, Monika;
Tomczyk, Michał;
Wiater, Adrian;
Woytoń, Aleksandra;
Junka, Adam

Publication type:

Article

Transthyretin Amyloid Cardiomyopathy—2025 Update: Current Diagnostic Approaches and Emerging Therapeutic Options.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 13, p. 4785, doi. 10.3390/jcm14134785

By:

Tschöpe, Carsten;
Elsanhoury, Ahmed;
Kristen, Arnt V.

Publication type:

Article

Primary Plasma Cell Leukemia: Recent Advances in Molecular Understanding and Treatment Approaches.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6166, doi. 10.3390/ijms26136166

By:

Hanamura, Ichiro;
Karnan, Sivasundaram;
Ota, Akinobu;
Takami, Akiyoshi

Publication type:

Article

Potent ferroptosis agent RSL3 induces cleavage of Pyroptosis-Specific gasdermins in Cancer cells.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-11368-1

By:

Herrick, William G.;
Tran, Huong-Lan;
Tomaino, Francesca R.;
Beall, Brittany;
Govindharajulu, Jeevan;
Esposito, Dominic;
Kuhlmann, Laura;
Parchment, Ralph E.;
Doroshow, James H.;
Srivastava, Apurva K.

Publication type:

Article

Editorial: New insights into the pathogenesis of idiopathic inflammatory myopathy.

Published in:

2025

By:

Ascherman, Dana P.

Publication type:

Editorial

Neutrophils aggravate inflammatory lesions in intestinal organoids from necrotizing enterocolitis.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1582526

By:

Heuer, Kim M.;
Boettcher, Michael;
Raluy, Laia Pagerols;
Hagens, Johanna;
Kolman, Jan P.;
Bunders, Madeleine J.;
Wesche, Jasmin;
Knopf, Jasmin;
Herrmann, Martin;
Reinshagen, Konrad;
Vincent, Deirdre

Publication type:

Article

Somatic Mosaic NLRC4 Variants in Autoinflammatory Diseases: Functional Characterization and Correlation of Mosaicism Levels with Disease Age of Onset and Severity.

Published in:

Journal of Clinical Immunology, 2025, v. 45, n. 1, p. 1, doi. 10.1007/s10875-025-01907-w

By:

Diab, Farah;
Louvrier, Camille;
Fabre, Marc;
Lin, Christine;
Rabbaa, Mira;
Assrawi, Eman;
Daskalopoulou, Aphrodite;
Mani, Rahma;
Dastot Le Moal, Florence;
Piterboth, William;
Legendre, Marie;
Amselem, Serge;
Karabina, Sonia Athina;
Giurgea, Irina

Publication type:

Article

The Road to a New Horizon in Psoriatic Arthritis.

Published in:

Journal of Rheumatology, 2025, v. 52, p. 1, doi. 10.3899/jrheum.2025-0330

By:

Gladman, Dafna D.

Publication type:

Article

Contemporary management paradigms and emerging therapeutics for myelodysplastic syndromes/neoplasms.

Published in:

British Journal of Haematology, 2025, v. 206, n. 6, p. 1571, doi. 10.1111/bjh.20116

By:

Ramanathan, Ramkarthic;
Xie, Yiyu;
Badar, Talha;
Zeidan, Amer M.;
Patel, Shyam A.

Publication type:

Article

In vitro susceptibility testing of Trichomonas gallinae strains to proton pump inhibitors and nitroimidazoles.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10668-w

By:

Kerek, Ádám;
Csiki, Boglárka Bianka;
Szabó, Ábel;
Farkas, Máté;
Pitó, Andor;
Jerzsele, Ákos;
Mag, Patrik

Publication type:

Article

Top advances of the year: Sarcoma.

Published in:

Cancer (0008543X), 2025, v. 131, n. 13, p. 1, doi. 10.1002/cncr.35965

By:

Vierra, Mason;
Brett, Jamie;
Wang, Jiping

Publication type:

Article

Molecular and immunohistochemical characterization of ERBB2 activating mutations in low‐grade serous ovarian carcinoma.

Published in:

Histopathology, 2025, v. 87, n. 2, p. 310, doi. 10.1111/his.15452

By:

Neil, Alexander J;
Nkosi, Dingani;
Yoon, Ju‐Yoon;
Kolin, David L;
Sholl, Lynette M

Publication type:

Article

Exploring the unknown: rare primary brain tumors -- diagnosis and treatment.

Published in:

Oncology in Clinical Practice (2450-1654), 2025, v. 21, n. 3, p. 206, doi. 10.5603/ocp.104716

By:

Dziedzic, Elżbieta;
Turkiewicz, Joanna;
Zapędowska, Jolanta;
Kawecki, Andrzej

Publication type:

Article

Alternative treatment for recurrent keloids: initial clinical experience with Rhenium-188 using a specialized device.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2025, v. 52, n. 9, p. 3151, doi. 10.1007/s00259-025-07184-4

By:

Mokoala, Kgomotso M. G.;
Nonjola, Linda;
Moeng, Thabiso;
Corbett, Cecilia;
Magwaza, Martin;
Dahlhoff, Gerhard;
Brown, Shannon;
Vetter, Nicholas;
Vorster, Mariza;
Sathekge, Mike Machaba

Publication type:

Article

Physiological, Chemical and Metabolite Profiling of Pectobacterium carotovorum -Inoculated Tomato Plants Grown in Nutrient-Amended Soils.

Published in:

Plants (2223-7747), 2025, v. 14, n. 12, p. 1876, doi. 10.3390/plants14121876

By:

Maluleke, Sandra;
Ogugua, Udoka Vitus;
Mdluli, Njabulo;
Madala, Ntakadzeni Edwin;
Ntushelo, Khayalethu

Publication type:

Article

Optimized Carbon–Nitrogen Fertilization Boosts Fragrant Rice (Oryza sativa L.) Yield and Quality via Enhanced Photosynthesis, Antioxidant Defense, and Osmoregulation.

Published in:

Plants (2223-7747), 2025, v. 14, n. 12, p. 1832, doi. 10.3390/plants14121832

By:

Xie, Wenjun;
Jiang, Zhe;
Lin, Li;
Wang, Xinyi;
Zhang, Lihe;
Mo, Zhaowen

Publication type:

Article

Studies on low pressure air plasma treatment to tasar (antheraea mylitta d.), muga (antheraea assama ww.) and eri (philosamia ricini b.) silk.

Published in:

Man-Made Textiles in India, 2020, v. 48, n. 7, p. 239

By:

Das, Subrata

Publication type:

Article

Psychophysiological Effects of Different Methods of Inducing Restoration Needs.

Published in:

Psychological Reports, 2021, v. 124, n. 1, p. 131, doi. 10.1177/0033294119898121

By:

Han, Ke-Tsung

Publication type:

Article

Development of a clinical scale for assessment of patients with diffuse intrinsic pontine glioma (DIPG) receiving experimental therapy: the PONScore.

Published in:

Journal of Neuro-Oncology, 2020, v. 149, n. 2, p. 263, doi. 10.1007/s11060-020-03594-6

By:

Hollingworth, Milo Alexander;
Zacharoulis, Stergios

Publication type:

Article

Hypofractionated radiotherapy with temozolomide in diffuse intrinsic pontine gliomas: a randomized controlled trial.

Published in:

Journal of Neuro-Oncology, 2020, v. 146, n. 1, p. 91, doi. 10.1007/s11060-019-03340-7

By:

Izzuddeen, Yousra;
Gupta, Subhash;
Haresh, K. P.;
Sharma, Dayanand;
Giridhar, Prashanth;
Rath, Gour Kishore

Publication type:

Article

Treatment of digital ulcers in systemic sclerosis: recent developments and future perspectives.

Published in:

Clinical Rheumatology, 2023, v. 42, n. 10, p. 2589, doi. 10.1007/s10067-023-06511-0

By:

Sagonas, Ioannis;
Daoussis, Dimitrios

Publication type:

Article

A systematic review and network meta-analysis of current and investigational treatments for active ankylosing spondylitis.

Published in:

Clinical Rheumatology, 2020, v. 39, n. 8, p. 2307, doi. 10.1007/s10067-020-04970-3

By:

Deodhar, A.;
Chakravarty, S. D.;
Cameron, C.;
Peterson, S.;
Hensman, R.;
Fogarty, S.;
Spin, P.;
Kafka, S.;
Nair, S.;
Gensler, L. S.

Publication type:

Article

Traffic noise alters individual social connectivity, but not space-use, of Red-backed Fairywrens.

Published in:

Emu (0158-4197), 2020, v. 120, n. 4, p. 313, doi. 10.1080/01584197.2020.1830706

By:

Hawkins, Carly E.;
Ritrovato, Isabel T.;
Swaddle, John P.

Publication type:

Article

The effect of radiotherapy on patients with EGFR-driven lung cancer brain metastasis: a systematic review and meta-analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02780-0

By:

Habibi, Mohammad Amin;
Rashidi, Farhang;
Delbari, Pourya;
Hajikarimloo, Bardia;
Hojjat, Seyed Hesam;
Kazemivand, Sana;
Fathi Tavani, Sahar;
Bahri, Amirmohammad;
Shahir Eftekhar, Mohammad;
Gandomkar, Hossein;
Mohammadzadeh, Ibrahim

Publication type:

Article

HER2 prognostic values in non-muscle-invasive bladder cancer: a step towards personalized treatment for BCG instillation.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02751-5

By:

Deng, Xinpei;
Zheng, Runhao;
Tan, Xingliang;
Yao, Kai

Publication type:

Article

Unveiling the microbial orchestra: exploring the role of microbiota in cancer development and treatment.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02352-2

By:

Alum, Esther Ugo;
Uti, Daniel Ejim;
Ugwu, Okechukwu Paul-Chima;
Alum, Benedict Nnachi;
Edeh, Friday Ogbu;
Ainebyoona, Christine

Publication type:

Article

A bibliometric analysis of programmed cell death in oral cancer literature: research patterns and emerging trends (2000–2024).

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02410-9

By:

Gu, Wenli

Publication type:

Article

Biological roles and clinical applications of EpCAM in HCC.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02095-0

By:

Liu, Peng;
Zhang, Qun;
Liu, Fengchao

Publication type:

Article

Could a simple model of COVID-19 infections be the key to designing better virus-based therapies?

Published in:

Synthetic Biology (23977000), 2022, v. 7, n. 1, p. 1, doi. 10.1093/synbio/ysac019

By:

King, Connor R

Publication type:

Article

Utilisation of slow-release non-protein nitrogen produced from agro-industrial by-products: feed digestibility and ruminal parameters.

Published in:

Journal of Animal & Feed Sciences, 2023, v. 32, n. 1, p. 76, doi. 10.22358/jafs/153864/2022

By:

Amani-Yengejeh, M.;
Taghizadeh, A.;
Mohammadzadeh, H.;
Hosseinkhani, A.;
Shirmohammadi, S.;
Abachi, S.;
Palangi, V.;
Eseceli, H.;
Besharati, M.;
Giannenas, I.

Publication type:

Article

Male mate guarding in a polyandrous and sexually cannibalistic praying mantid.

Published in:

Behavioral Ecology & Sociobiology, 2024, v. 78, n. 7, p. 1, doi. 10.1007/s00265-024-03500-4

By:

Nishino, Hiroto;
Morimoto, Kotaro;
Kuroda, Kazuki;
Takami, Yasuoki

Publication type:

Article

Female remating decisions and mate choice benefits in the beetle Gnatocerus cornutus.

Published in:

Behavioral Ecology & Sociobiology, 2022, v. 76, n. 4, p. 1, doi. 10.1007/s00265-022-03161-1

By:

Kiyose, Katsuya;
Katsuki, Masako;
Suzaki, Yû;
Okada, Kensuke

Publication type:

Article

Interplay between ALK2<sup>R206H</sup> mutant receptor and autophagy signaling regulates receptor stability and its chondrogenic functions.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02393-0

By:

Coculo, Laura;
Wits, Marius;
Mariani, Irene;
Fianco, Giulia;
Cappato, Serena;
Bocciardi, Renata;
Pedemonte, Nicoletta;
Volpe, Elisabetta;
Ciolfi, Serena;
Sessa, Rosario Luigi;
Rinaldo, Serena;
Cutruzzolà, Francesca;
Trisciuoglio, Daniela;
Goumans, Marie-Josè;
Sanchez-Duffhues, Gonzalo;
Stagni, Venturina

Publication type:

Article

Updates in Intestinal Failure Management.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 9, p. 3031, doi. 10.3390/jcm14093031

By:

Wang, Sarah Z.;
O'Daniel, Elizabeth L.

Publication type:

Article

Reply to Confalonieri et al. Comment on "Colombo et al. Managing Retinitis Pigmentosa: A Literature Review of Current Non-Surgical Approaches. J. Clin. Med. 2025, 14 , 330".

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 8, p. 2557, doi. 10.3390/jcm14082557

By:

Colombo, Leonardo;
Baldesi, Jacopo;
Martella, Salvatore;
Quisisana, Chiara;
Antico, Aleksei;
Mapelli, Luca;
Montagner, Stefania;
Primon, Alberto;
Rossetti, Luca

Publication type:

Article

The Efficacy of Carfilzomib Treatment in Bortezomib-Refractory Patients—Real Life Experience in a Tertiary Romanian Hospital.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 8, p. 2171, doi. 10.3390/jcm13082171

By:

Irimia, Ruxandra;
Badelita, Sorina Nicoleta;
Barbu, Sinziana;
Zidaru, Larisa;
Carlan, Ioana Loredana;
Coriu, Daniel

Publication type:

Article

HBV and HDV: New Treatments on the Horizon.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 18, p. 4054, doi. 10.3390/jcm10184054

By:

Zuccaro, Valentina;
Asperges, Erika;
Colaneri, Marta;
Marvulli, Lea Nadia;
Bruno, Raffaele

Publication type:

Article

Challenges in Clinical Management of Radiation-Induced Illnesses During Exploration Spaceflight.

Published in:

Aerospace Medicine & Human Performance, 2019, v. 90, n. 11, p. 966, doi. 10.3357/AMHP.5370.2019

By:

Blue, Rebecca S.;
Chancellor, Jeffery C.;
Suresh, Rahul;
Carnell, Lisa S.;
Reyes, David P.;
Nowadly, Craig D.;
Antonsen, Erik L.

Publication type:

Article

Mehrjährige Schwarzbrache: Eine geeignete Methode zur Erdmandelgras-Bekämpfung.

Published in:

Julius-Kühn-Archiv, 2022, n. 468, p. 128, doi. 10.5073/20220117-135135

By:

Wirth, Judith;
Willi, Marco;
Keller, Martina

Publication type:

Article

Mycotoxin exposure and its impact on inflammatory response and growth in pigs and intestinal epithelial cells.

Published in:

Journal of Animal Science, 2025, v. 103, p. 320, doi. 10.1093/jas/skaf102.355

By:

Brackett, Madison N.;
Lawal, Abiola S.;
Yuechi Fu;
Horn, Nathan;
Ajuwon, Kolapo M.

Publication type:

Article

Effects of standardized ileal digestible lysine: Crude protein ratio in diets with or without distiller’s dried grains with solubles on growth performance of 11- to 20-kg pigs.

Published in:

Journal of Animal Science, 2025, v. 103, p. 306, doi. 10.1093/jas/skaf102.341

By:

Smallfield, essica L.;
Tokach, Michael D.;
Gaffield, Katelyn N.;
Gebhardt, Jordan T.;
Goodband, Robert D.;
DeRouchey, Joel M.;
Woodworth, Jason C.;
Cemin, Henrique S.;
Soto, Jose A.;
Pietig, Melissa;
Schumacher, Zach

Publication type:

Article

Effects of standardized ileal digestible lysine:crude protein ratio on growth performance of 11- to 25-kg pigs.

Published in:

Journal of Animal Science, 2025, v. 103, p. 101, doi. 10.1093/jas/skaf102.109

By:

Smallfield, Jessica L.;
Gebhardt, Jordan T.;
Gaffield, Katelyn N.;
Tokach, Michael D.;
Woodworth, Jason C.;
Goodband, Robert D.;
DeRouchey, Joel M.;
Shawk, Dwight;
Gainey, Noah

Publication type:

Article

Effects of water-delivered microencapsulated essential oils and F18+ Escherichia coli vaccine on growth performance and post-weaning diarrhea in weanling pigs.

Published in:

2025

By:

Scinto, Sara B.;
Ng, Vanessa W. Y.;
Fisk, Alexandra E.;
Klassen, Katherine E.;
Licuan, Daphne A.;
Cecil, Mekenzie R.;
Long, Erica A.;
Schinckel, Allan P.;
Richert, Jacob A.;
Scharlau, Carson;
Fent, Russell W.;
Tingting Ju;
Richert, Brian T.

Publication type:

Abstract

Use of a commercial blend of tannins as feed additive for feed lot cattle on large pen trial improves carcass weight and carcass feed conversion.

Published in:

Journal of Animal Science, 2024, v. 102, p. 778, doi. 10.1093/jas/skae234.877

By:

Manella, Marcelo Q.;
Campanini, Andre;
Boin, Celso;
Paula, Eduardo;
Branco Arnandes, Renata;
Lopes, Vagner

Publication type:

Article

Evaluation of a phytogenic feed additive containing garlic, clove, and capsicum oleoresin on the health and performance of newly received, high-risk calves.

Published in:

Journal of Animal Science, 2024, v. 102, p. 333, doi. 10.1093/jas/skae234.380

By:

Wilson, Blake K.;
Owen, Natally;
Heldt, Jeff S.

Publication type:

Article

Effects of multi-carbohydrase and protease supple- mentation on ileal digestibility of amino acids in expeller-pressed canola meal fed to growing pigs.

Published in:

2024

By:

Jinyoung Lee;
Olivo, Alicia;
Patterson, Rob;
Nyachoti, C. Martin

Publication type:

Abstract