Works about INTERLEUKIN-2

Results: 3163

Essential cell-intrinsic requirement for GMDS in T cell development.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1598923

By:

Yabas, Mehmet;
Roots, Carla M.;
Andrews, T. Daniel;
Field, Matt A.;
Goodnow, Christopher C.;
Enders, Anselm

Publication type:

Article

Regulatory T cells attenuate chronic inflammation and cardiac fibrosis in hypertrophic cardiomyopathy.

Published in:

Science Translational Medicine, 2025, v. 17, n. 806, p. 1, doi. 10.1126/scitranslmed.adq3516

By:

Wang, Ying-Jie;
Singh, Kamayani;
Lokman, Adam B.;
Deng, Siwei;
Sunitha, Balaraju;
Coelho Lima Jr., Jose;
Beglov, Julia;
Kelly, Matthew;
Blease, Andrew;
Fung, Jacky C. K.;
Huang, Anan;
Attar, Moustafa;
Stork, Lee-Anne;
Maguire, Mahon L.;
Schneider, Jürgen E.;
Marston, Steve B.;
Soilleux, Elizabeth J.;
Dendrou, Calliope A.;
Coles, Mark;
Buckley, Christopher D.

Publication type:

Article

Co-expression of IL-15/IL-15Ra complex enhances NKG2D-CAR T cell-mediated anti-pancreatic cancer immunity by activating the JAK/STAT5 signaling pathway.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1498706

By:

Chen, Yiran;
Jin, Chenxu;
Guo, Dandan;
Hui, Xinhui;
Ji, Yuzhou;
Huang, Yunhe;
Xue, Min;
Gao, Yaoxin;
Ren, Yaojun;
Lin, Haizhen;
Zhou, Ying;
Jiang, Wenzheng

Publication type:

Article

Thioredoxin regulates T cell proliferation and aggravates the severity of influenza a virus infection.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10676-w

By:

Shen, Li;
Yang, Jing;
Liu, Jin;
Zhang, Yue;
Wu, Yue;
Xu, Hong

Publication type:

Article

Effect of Paliperidone Combined with Sertraline in the Treatment of Schizophrenia and its Influence on Serum Neurofunctional Related Factors.

Published in:

Alpha Psychiatry, 2025, v. 26, n. 1, p. 1, doi. 10.31083/AP38775

By:

Meng Gu;
Zhilian Pi;
Long Zhu;
Jun Zhang

Publication type:

Article

杂合施护对脊髓损伤后 NBD 病人肠道症状和炎症水平的影响.

Published in:

Chinese Nursing Research, 2021, v. 35, n. 20, p. 3637, doi. 10.12102/j.issn.1009-6493.2021.20.012

By:

刘静;
阳煜;
张达慧;
吴晓敏;
刘艳雨;
谢静仪;
卢秀玲;
胡颖

Publication type:

Article

Selective intestinal decontamination with norfloxacin enhances a regulatory T cell-mediated inflammatory control mechanism in cirrhosis.

Published in:

Liver International, 2016, v. 36, n. 12, p. 1811, doi. 10.1111/liv.13172

By:

Juanola, Oriol;
Gómez ‐ Hurtado, Isabel;
Zapater, Pedro;
Moratalla, Alba;
Caparrós, Esther;
Piñero, Paula;
González ‐ Navajas, José M.;
Giménez, Paula;
Such, José;
Francés, Rubén

Publication type:

Article

Genetic variation in interleukin 28B and correlation with chronic hepatitis B virus infection in Saudi Arabian patients.

Published in:

Liver International, 2014, v. 34, n. 7, p. e208, doi. 10.1111/liv.12347

By:

Al-Qahtani, Ahmed A.;
Al-Anazi, Mashael R.;
Abdo, Ayman A.;
Sanai, Faisal M.;
Al-Hamoudi, Waleed K.;
Alswat, Khalid A.;
Al-Ashgar, Hamad I.;
Khalaf, Nisreen Z.;
Viswan, Nisha A.;
Al Ahdal, Mohammed N.

Publication type:

Article

Triptolide reverses helper T cell inhibition and down-regulates IFN-γ induced PD-L1 expression in glioma cell lines.

Published in:

Journal of Neuro-Oncology, 2019, v. 143, n. 3, p. 429, doi. 10.1007/s11060-019-03193-0

By:

Zhang, Lei;
Yu, John S.

Publication type:

Article

Immunogene therapy using immunomodulating HVJ-E vector augments anti-tumor effects in murine malignant glioma.

Published in:

Journal of Neuro-Oncology, 2011, v. 103, n. 1, p. 19, doi. 10.1007/s11060-010-0355-x

By:

Matsuda, Masahide;
Nimura, Keisuke;
Shimbo, Takashi;
Hamasaki, Toshimitsu;
Yamamoto, Tetsuya;
Matsumura, Akira;
Kaneda, Yasufumi

Publication type:

Article

Immersion in the search for effective cancer immunotherapies.

Published in:

2021

By:

Rosenberg, Steven A.

Publication type:

Editorial

Comparison of serum IL-1β, sIL-2R, IL-6, and TNF-α levels with disease activity parameters in ankylosing spondylitis.

Published in:

Clinical Rheumatology, 2007, v. 26, n. 2, p. 211, doi. 10.1007/s10067-006-0283-5

By:

Bal, A.;
Unlu, E.;
Bahar, G.;
Aydog, E.;
Eksioglu, E.;
Yorgancioglu, R.

Publication type:

Article

Ex vivo monitoring of protein production in baculovirus-infected Trichoplusia ni larvae with a GFP-specific optical probe.

Published in:

Biotechnology & Bioengineering, 2003, v. 83, n. 2, p. 241, doi. 10.1002/bit.10668

By:

Shannon F. Kramer;
Yordan Kostov;
Govind Rao

Publication type:

Article

Cervical lymph node extirpation for the diagnosis of malignant lymphoma.

Published in:

Surgery Today, 2013, v. 43, n. 1, p. 67, doi. 10.1007/s00595-012-0149-1

By:

Orita, Yorihisa;
Nose, Soichiro;
Sato, Yasuharu;
Miki, Kentaro;
Domae, Shuhei;
Hirai, Misato;
Noyama, Yasuyuki;
Hamaya, Kazuo;
Kasai, Norio;
Nishizaki, Kazunori;
Yoshino, Tadashi

Publication type:

Article

Clinical evaluation of leukocyte filtration as an alternative anti-inflammatory strategy to aprotinin in high-risk patients undergoing coronary revascularization.

Published in:

Surgery Today, 2012, v. 42, n. 4, p. 334, doi. 10.1007/s00595-011-0012-9

By:

Farsak, Bora;
Gunaydin, Serdar;
Yildiz, Ulku;
Sari, Tamer;
Zorlutuna, Yaman

Publication type:

Article

Pediatric patients receiving ABO-incompatible living related liver transplantation exhibit higher serum transforming growth factor-β1, interferon-γ and interleukin-2 levels.

Published in:

2011

By:

Hussein, Mohamed;
Hashimoto, Takashi;
AbdEl-Hamid Daoud, Ghada;
Kato, Takazumi;
Hibi, Masahito;
Tomishige, Hirokazu;
Hara, Fujio;
Suzuki, Tatsuya;
Nakajima, Yoko;
Goto, Tatenobu;
Ito, Tetsuya;
Kato, Ineko;
Sugioka, Atsushi;
Togari, Hajime;
Hussein, Mohamed Hamed

Publication type:

journal article

Neuroblastoma: treatment outcome after incomplete resection of primary tumors.

Published in:

2009

By:

Suk-Bae Moon;
Kwi-Won Park;
Sung-Eun Jung;
Woong-Jae Youn;
Moon, Suk-Bae;
Park, Kwi-Won;
Jung, Sung-Eun;
Youn, Woong-Jae

Publication type:

journal article

Tumor necrosis therapy antibody interleukin-2 fusion protein elicits prolonged and targeted antitumor effects in vivo.

Published in:

Applied Microbiology & Biotechnology, 2014, v. 98, n. 9, p. 4053, doi. 10.1007/s00253-013-5349-0

By:

Ye, Li;
Fan, Jiajun;
Shi, Xunlong;
Tao, Qun;
Ye, Dan;
Xian, Zongshu;
Zeng, Xian;
Li, Yubin;
Feng, Meiqing;
Ju, Dianwen

Publication type:

Article

Clinical and Safety Profile of High-Dose Interleukin-2 Treatment in Elderly Patients with Metastatic Melanoma and Renal Cell Carcinoma.

Published in:

Oncology, 2012, v. 84, n. 2, p. 123, doi. 10.1159/000342764

By:

Clark, James M.;
Kelley, Benjamin;
Titze, Jill;
Fung, Henry;
Maciejewski, John;
Nathan, Sunita;
Rich, Elizabeth;
Basu, Sanjib;
Kaufman, Howard L.

Publication type:

Article

How Can Second-Line Therapy for Metastatic Renal Cell Carcinoma Help to Define an Overall Management Strategy?

Published in:

Oncology, 2009, v. 77, n. 2, p. 82, doi. 10.1159/000228835

By:

Melichar, Bohuslav

Publication type:

Article

Chronically Administered Immunotherapy with Low-Dose IL-2 and IFN-α in Metastatic Renal Cell Carcinoma: A Feasible Option for Patients with a Good Prognostic Profile.

Published in:

Oncology, 2009, v. 76, n. 1, p. 69, doi. 10.1159/000178810

By:

Vaglio, Augusto;
Alberici, Federico;
Maggiore, Umberto;
Buti, Sebastiano;
Potenzoni, Domenico;
Passalacqua, Rodolfo;
Buzio, Carlo

Publication type:

Article

Interleukin-2-Based Biochemotherapy for Patients with Stage IV Melanoma: Long-Term Survivors Outside a Clinical Trial Setting.

Published in:

Oncology, 2007, v. 73, n. 1/2, p. 33, doi. 10.1159/000120029

By:

Hess, Viviane;
Herrmann, Richard;
Veelken, Hendrik;
Schwabe, Michael

Publication type:

Article

Phenotypic and functional analysis of tumor-infiltrating lymphocytes compared with tumor-associated lymphocytes from ascitic fluid and peripheral blood lymphocytes in patients with advanced ovarian cancer.

Published in:

2001

By:

Santin, A.D.;
Hermonat, P.L.;
Ravaggi, A.;
Bellone, S.;
Roman, J.J.;
Smith, C.V.;
Pecorelli, S.;
Radominska-Pandya, A.;
Cannon, M.J.;
Parham, G.P.

Publication type:

journal article

Lymphokine-activated killer activity in women with endometriosis.

Published in:

1994

By:

Oosterlynck, Didier J.;
Lacquet, Françoise A.;
Waer, Mark;
Koninckx, Philippe R.;
Oosterlynck, D J;
Lacquet, F A;
Waer, M;
Koninckx, P R

Publication type:

journal article

Immunology: Control of T-cell development.

Published in:

Nature, 1985, p. 16

By:

Scollay, Roland

Publication type:

Article

Isomorphic (Koebner) Phenomenon Induced by Insulin Analogue Injections in Psoriasis.

Published in:

JCEM Case Reports, 2023, v. 1, n. 1, p. 1, doi. 10.1210/jcemcr/luac016

By:

Thijs, Saartje;
Balti, Eric;
Degraeve, Corinne;
Coremans, Peter

Publication type:

Article

Maturation of effector regulatory T cells.

Published in:

Nature Immunology, 2011, v. 12, n. 4, p. 283, doi. 10.1038/ni0411-283

By:

Ohkura, Naganari;
Sakaguchi, Shimon

Publication type:

Article

The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes.

Published in:

Nature Immunology, 2010, v. 11, n. 11, p. 1057, doi. 10.1038/ni.1945

By:

Stittrich, Anna-Barbara;
Haftmann, Claudia;
Sgouroudis, Evridiki;
Kühl, Anja Andrea;
Hegazy, Ahmed Nabil;
Panse, Isabel;
Riedel, Rene;
Flossdorf, Michael;
Dong, Jun;
Fuhrmann, Franziska;
Heinz, Gitta Anne;
Fang, Zhuo;
Li, Na;
Bissels, Ute;
Hatam, Farahnaz;
Jahn, Angelina;
Hammoud, Ben;
Matz, Mareen;
Schulze, Felix-Michael;
Baumgrass, Ria

Publication type:

Article

Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells.

Published in:

Nature Immunology, 2010, v. 11, n. 9, p. 862, doi. 10.1038/ni.1917

By:

Cardone, John;
Le Friec, Gaelle;
Vantourout, Pierre;
Roberts, Andrew;
Fuchs, Anja;
Jackson, Ian;
Suddason, Tesha;
Lord, Graham;
Atkinson, John P;
Cope, Andrew;
Hayday, Adrian;
Kemper, Claudia

Publication type:

Article

Sensing the outside world: TSLP regulates barrier immunity.

Published in:

Nature Immunology, 2010, v. 11, n. 4, p. 289, doi. 10.1038/ni.1852

By:

Ziegler, Steven F;
Artis, David

Publication type:

Article

T cell–intrinsic role of Nod2 in promoting type 1 immunity to Toxoplasma gondii.

Published in:

Nature Immunology, 2009, v. 10, n. 12, p. 1267, doi. 10.1038/ni.1816

By:

Shaw, Michael H.;
Reimer, Thornik;
Sánchez-Valdepeñas, Carmen;
Warner, Neil;
Yun-Gi Kim;
Fresno, Manuel;
Nuñez, Gabriel

Publication type:

Article

T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-α.

Published in:

Nature Immunology, 2006, v. 7, n. 11, p. 1166, doi. 10.1038/ni1394

By:

Yuanyuan Zha;
Marks, Reinhard;
Ho, Allen W.;
Peterson, Amy C.;
Janardhan, Sujit;
Brown, Ian;
Praveen, Kesavannair;
Stang, Stacey;
Stone, James C.;
Gajewski, Thomas F.

Publication type:

Article

A pathway regulated by cell cycle inhibitor p27Kip1 and checkpoint inhibitor Smad3 is involved in the induction of T cell tolerance.

Published in:

Nature Immunology, 2006, v. 7, n. 11, p. 1157, doi. 10.1038/ni1398

By:

Lequn Li;
Iwamoto, Yoshiko;
Berezovskaya, Alla;
Boussiotis, Vassiliki A

Publication type:

Article

Disruption of diacylglycerol metabolism impairs the induction of T cell anergy.

Published in:

Nature Immunology, 2006, v. 7, n. 11, p. 1174, doi. 10.1038/ni1400

By:

Olenchock, Benjamin A.;
Guo, Rishu;
Carpenter, Jeffery H.;
Jordan, Martha;
Topham, Matthew K.;
Koretzky, Gary A.;
Xiao-Ping Zhong

Publication type:

Article

Research Highlights.

Published in:: Nature Immunology, 2006, v. 7, n. 4, p. 373, doi. 10.1038/ni0406-373
Publication type:: Article

Erratum: A function for interleukin 2 in Foxp3-expressing regulatory T cells.

Published in:

2006

By:

Fontenot, Jason D.;
Rasmussen, Jeffrey P.;
Gavin, Marc A.;
Rudensky, Alexander Y.

Publication type:

Correction Notice

Fueling regulation: IL-2 keeps CD4+ Treg cells fit.

Published in:

Nature Immunology, 2005, v. 6, n. 11, p. 1071, doi. 10.1038/ni1105-1071

By:

Maloy, Kevin J.;
Powrie, Fiona

Publication type:

Article

A function for interleukin 2 in Foxp3-expressing regulatory T cells.

Published in:

Nature Immunology, 2005, v. 6, n. 11, p. 1142, doi. 10.1038/ni1263

By:

Fontenot, Jason D.;
Rasmussen, Jeffrey P.;
Gavin, Marc A.;
Rudensky, Alexander Y.

Publication type:

Article

Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling.

Published in:

Nature Immunology, 2005, v. 6, n. 11, p. 1152, doi. 10.1038/ni1264

By:

D'Cruz, Louise M.;
Klein, Ludger

Publication type:

Article

CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2.

Published in:

Nature Immunology, 2005, v. 6, n. 2, p. 152, doi. 10.1038/ni1160

By:

Tai, Xuguang;
Cowan, Michelle;
Feigenbaum, Lionel;
Singer, Alfred

Publication type:

Article

Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation.

Published in:

Nature Immunology, 2004, v. 5, n. 4, p. 435, doi. 10.1038/ni1044

By:

Andres, Pietro G.;
Howland, Kimberly C.;
Nirula, Ajay;
Kane, Lawrence P.;
Barron, Luke;
Dresnek, Douglas;
Sadra, Ali;
Imboden, John;
Weiss, Arthur;
Abbas, Abul K.

Publication type:

Article

More negative feedback?

Published in:

Nature Immunology, 2003, v. 4, n. 7, p. 647, doi. 10.1038/ni0703-647

By:

Coyle, Anthony J;
Gutierrez-Ramos, Jose-Carlos

Publication type:

Article

Il2 transcription unleashed by active DNA demethylation.

Published in:

Nature Immunology, 2003, v. 4, n. 3, p. 208, doi. 10.1038/ni0303-208

By:

Bird, Adrian

Publication type:

Article

Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process.

Published in:

Nature Immunology, 2003, v. 4, n. 3, p. 235, doi. 10.1038/ni887

By:

Bruniquel, Denis;
Schwartz, Ronald H.

Publication type:

Article

Involvement of inhibitory NKRs in the survival of a subset of memory-phenotype CD8+ T cells.

Published in:

Nature Immunology, 2001, v. 2, n. 5, p. 430, doi. 10.1038/87740

By:

Ugolini, Sophie;
Arpin, Christophe;
Anfossi, Nicolas;
Walzer, Thierry;
Cambiaggi, Anna;
Förster, Reinhold;
Lipp, Martin;
Toes, René E. M.;
Melief, Cornelius J.;
Marvel, Jacqueline;
Vivier, Eric

Publication type:

Article

Serum soluble interleukin-2 receptor as a biomarker in immunoglobulin G4-related disease.

Published in:

Modern Rheumatology, 2018, v. 28, n. 5, p. 838, doi. 10.1080/14397595.2017.1416739

By:

Tomohiro Handa;
Shoko Matsui;
Hajime Yoshifuji;
Yuzo Kodama;
Hiroshi Yamamoto;
Seijiro Minamoto;
Yuko Waseda;
Yasuharu Sato;
Keishi Kubo;
Tsuneyo Mimori;
Tsutomu Chiba;
Toyohiro Hirai;
Michiaki Mishima

Publication type:

Article

Suppressor of TCR signaling-2 (STS-2) suppresses arthritis development in mice.

Published in:

Modern Rheumatology, 2018, v. 28, n. 4, p. 626, doi. 10.1080/14397595.2017.1380249

By:

Namiko Okabe;
Koichiro Ohmura;
Masaki Katayama;
Shuji Akizuki;
Nick Carpino;
Kosaku Murakami;
Ran Nakashima;
Motomu Hashimoto;
Yoshitaka Imura;
Hajime Yoshifuji;
Masao Tanaka;
Tsuneyo Mimori

Publication type:

Article

Rheumatoid arthritis complicated with immunodeficiency-associated lymphoproliferative disorders during treatment with adalimumab.

Published in:

Modern Rheumatology, 2012, v. 22, n. 3, p. 458, doi. 10.3109/s10165-011-0501-0

By:

Ikeda, Takahide;
Toyama, Syoko;
Ogasawara, Michihiro;
Amano, Hirohumi;
Takasaki, Yoshinari;
Morita, Hiroyuki;
Ishizuka, Tatsuo

Publication type:

Article

Continuous Release of Interleukin-2 from Liposomal IL-2 (Mixture of Interleukin-2 and Liposomes) After Subcutaneous Administration to Mice.

Published in:

Drug Development & Industrial Pharmacy, 2003, v. 29, n. 10, p. 1149, doi. 10.1081/DDC-120025872

By:

Kanaoka, Eri;
Takahashi, Kouji;
Yoshikawa, Takayoshi;
Jizomoto, Hiroaki;
Nishihara, Yoshitaka;
Hirano, Koichiro

Publication type:

Article

Mood and cytokine response to influenza virus in older adults.

Published in:

2004

By:

Costanzo, Erin S.;
Lutgendorf, Susan K.;
Kohut, Marian L.;
Nisly, Nicole;
Rozeboom, Kayla;
Spooner, Shawn;
Benda, JoAnn;
McElhaney, Janel E.;
McElhaney, Janet E

Publication type:

journal article