Works about INSULIN-like growth factor receptors

Results: 622

PRELP functions via multiple interactions with intrinsically weak affinity relying on ECM anchoring and remodeling.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-09018-7

By:

Kosuge, Hirofumi;
Nakakido, Makoto;
de Vega, Susana;
Ohnuma, Shin-ichi;
Tsumoto, Kouhei

Publication type:

Article

Role and mechanism of IGFBP5 in the real-ambient particulate matter exposure-induced chronic lung injury.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1604301

By:

Chen, Ningning;
Qi, Yuan;
Ma, Wanli;
Zhu, Xiaoxiao;
Li, Xiaoying

Publication type:

Article

Phosphorylated insulin-like growth factor-1 receptor (pIGF1R) is a poor prognostic factor in brain metastases from lung adenocarcinomas.

Published in:

Journal of Neuro-Oncology, 2013, v. 115, n. 1, p. 61, doi. 10.1007/s11060-013-1194-3

By:

Wu, Pei-Fang;
Huang, Wen-Chang;
Yang, James;
Lu, Yen-Shen;
Shih, Jin-Yuan;
Wu, Shang-Gin;
Lin, Ching-Hung;
Cheng, Ann-Lii

Publication type:

Article

Exosomes derived from BMSCs alleviates high glucose‐induced diabetic retinopathy via carrying miR‐483‐5p.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 1, p. 1, doi. 10.1002/jbt.23616

By:

Cao, Dan;
Zhou, Liang;
Hu, Rong

Publication type:

Article

Targeting Insulin and Insulin-Like Growth Factor Signaling in Breast Cancer.

Published in:

Journal of Mammary Gland Biology & Neoplasia, 2012, v. 17, n. 3/4, p. 251, doi. 10.1007/s10911-012-9268-y

By:

Yang, Yuzhe;
Yee, Douglas

Publication type:

Article

Potential Ototoxicity of Insulin-like Growth Factor 1 Receptor Signaling Inhibitors: An In Silico Drug Repurposing Study of the Regenerating Cochlear Neuron Transcriptome.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 10, p. 3485, doi. 10.3390/jcm12103485

By:

Bertagnoli, Lino E.;
Seist, Richard;
Batts, Shelley;
Stankovic, Konstantina M.

Publication type:

Article

Plasma microRNA-320a as a Potential Biomarker of Physiological Changes during Training in Professional Volleyball Players.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 1, p. 263, doi. 10.3390/jcm11010263

By:

Podgórski, Rafał;
Cieśla, Marek;
Podgórska, Dominika;
Bajorek, Wojciech;
Płonka, Artur;
Czarny, Wojciech;
Trybulski, Robert;
Król, Paweł

Publication type:

Article

Prioritization of Novel Agents for Patients with Rhabdomyosarcoma: A Report from the Children's Oncology Group (COG) New Agents for Rhabdomyosarcoma Task Force.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 7, p. 1416, doi. 10.3390/jcm10071416

By:

Pacenta, Holly L.;
Allen-Rhoades, Wendy;
Langenau, David;
Houghton, Peter J.;
Keller, Charles;
Heske, Christine M.;
Deel, Michael D.;
Linardic, Corinne M.;
Shern, Jack F.;
Stewart, Elizabeth;
Turpin, Brian;
Harrison, Douglas J.;
Khan, Javed;
Mascarenhas, Leo;
Skapek, Stephen X.;
Meyer, William H.;
Hawkins, Douglas S.;
Chen, Eleanor Y.;
Amatruda, James F.;
Hingorani, Pooja

Publication type:

Article

Effects of a methylation blend supplemented diet during gestation and lactation on skeletal muscle growth and molecular characteristics in piglets.

Published in:

Journal of Animal Science, 2025, v. 103, p. 277, doi. 10.1093/jas/skaf102.308

By:

Costa, Thais C.;
Da Silva Gomes, Maykelly;
Muniz, Maria M.;
Mingjia Jiang;
Ziting Li;
Silva, Walmir;
Qiong Hu;
Rocha, Gabriel C.;
Duarte, Marcio S.

Publication type:

Article

Melatonin supplementation to sows in mid to late gestation affects offspring circadian, myogenic, and growth factor transcript abundance in pre and postnatal skeletal muscle.

Published in:

Journal of Animal Science, 2024, v. 102, p. 1, doi. 10.1093/jas/skae377

By:

Dobbins, Thomas W;
Swanson, Rebecca M;
Dennis, Amberly A;
Rivera, J Daniel;
Dinh, Thu T N;
Lemley, Caleb O;
Burnett, Derris D

Publication type:

Article

Exogenous porcine somatotropin stimulates mammary development in late-pregnant gilts.

Published in:

Journal of Animal Science, 2019, v. 97, n. 6, p. 2433, doi. 10.1093/jas/skz136

By:

Farmer, Chantal;
Langendijk, Pieter

Publication type:

Article

Transcript abundance of hormone receptors, mammalian target of rapamycin pathway-related kinases, insulin-like growth factor I, and milk proteins in porcine mammary tissue.

Published in:

Journal of Animal Science, 2012, v. 90, n. 1, p. 221, doi. 10.2527/jas.2011-4179

By:

Manjarín, R.;
Steibel, J. P.;
Kirkwood, R. N.;
Taylor, N. P.;
Trottier, N. L.

Publication type:

Article

Elucidation of mRNA targets of miR-145-5p in diabetic kidney disease using bioinformatics analysis.

Published in:

Malaysian Journal of Medicine & Health Sciences, 2022, v. 18, p. 36, doi. 10.47836/mjmhs18.s21.7

By:

Sham, Siti Yazmin Zahari;
Azwar, Shamin;
Yip, Wai Kien;
Abdullah, Maha;
Thevandran, Kalaiselvam;
Osman, Malina;
Heng Fong Seow

Publication type:

Article

Specific insulin/IGF1 hybrid receptor activation assay reveals IGF1 as a more potent ligand than insulin.

Published in:

Scientific Reports, 2015, p. 7911, doi. 10.1038/srep07911

By:

Slaaby, Rita

Publication type:

Article

Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1575332

By:

Liao, Bin;
Wang, Pan;
Gong, Sheng;
Zhao, Lu;
Liu, Jie;
Wu, Nan

Publication type:

Article

Survivin in Insulin-Like Growth Factor-Induced Resistance to Lapatinib in Head and Neck Squamous Carcinoma Cells.

Published in:

Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00013

By:

Lehman, Christine E.;
Mendez, Rolando E.;
Dougherty, Michael I.;
Allak, Amir;
Adejumo, Oluwayemisi L.;
Taniguchi, Linnea E.;
Khalil, Ashraf;
Gioeli, Daniel G.;
Jameson, Mark J.

Publication type:

Article

Manipulating the tumor immune microenvironment to improve cancer immunotherapy: IGF1R, a promising target.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1356321

By:

Pellegrino, Marsha;
Secli, Valerio;
D’Amico, Silvia;
Petrilli, Lucia Lisa;
Caforio, Matteo;
Folgiero, Valentina;
Tumino, Nicola;
Vacca, Paola;
Vinci, Maria;
Fruci, Doriana;
de Billy, Emmanuel

Publication type:

Article

ATM Mutations Benefit Bladder Cancer Patients Treated With Immune Checkpoint Inhibitors by Acting on the Tumor Immune Microenvironment.

Published in:

Frontiers in Genetics, 2020, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.00933

By:

Yi, Ruibin;
Lin, Anqi;
Cao, Manming;
Xu, Abai;
Luo, Peng;
Zhang, Jian

Publication type:

Article

Investigational new insulin glargine 300 U/ml has the same metabolism as insulin glargine 100 U/ml.

Published in:

Diabetes, Obesity & Metabolism, 2014, v. 16, n. 9, p. 873, doi. 10.1111/dom.12283

By:

Steinstraesser, A.;
Schmidt, R.;
Bergmann, K.;
Dahmen, R.;
Becker, R. H. A.

Publication type:

Article

The combination of insulin-like growth factor 1 and erythropoietin protects against ischemic spinal cord injury in rabbits.

Published in:

Journal of Anesthesia, 2015, v. 29, n. 5, p. 741, doi. 10.1007/s00540-015-2031-y

By:

Utada, Kohji;
Ishida, Kazuyoshi;
Tohyama, Suguru;
Urushima, Yutaka;
Mizukami, Yoichi;
Yamashita, Atsuo;
Uchida, Masato;
Matsumoto, Mishiya

Publication type:

Article

Expression of insulin-like growth factor-1 receptor in keloid and hypertrophic scar.

Published in:

Clinical & Experimental Dermatology, 2014, v. 39, n. 7, p. 822, doi. 10.1111/ced.12407

By:

Hu, Z.‐C.;
Tang, B.;
Guo, D.;
Zhang, J.;
Liang, Y.‐Y.;
Ma, D.;
Zhu, J.‐Y.

Publication type:

Article

SUMO1 modification of IGF-1R combining with SNAI2 inhibited osteogenic differentiation of PDLSCs stimulated by high glucose.

Published in:

Stem Cell Research & Therapy, 2021, v. 12, n. 1, p. 1, doi. 10.1186/s13287-021-02618-w

By:

Jiang, Rongrong;
Wang, Miao;
Shen, Xiaobo;
Huang, Shuai;
Han, Jianpeng;
Li, Lei;
Xu, Zhiliang;
Jiang, Chengfeng;
Zhou, Qiao;
Feng, Xingmei

Publication type:

Article

IGF-1: a marker of individual life-span in a primate.

Published in:

Ageing Research, 2010, v. 1, n. 1, p. 1, doi. 10.4081/ar.2010.e2

By:

Aujard, Fabienne;
Bluet-Pajot, Marie Thérèse;
Zizzari, Philippe;
Perret, Martine;
Epelbaum, Jacques

Publication type:

Article

MicroRNA-503 inhibits the proliferation and invasion of breast cancer cells via targeting insulin-like growth factor 1 receptor.

Published in:

2022

By:

Yan, Jingwang;
Xu, Yonghuan;
Wang, Haipeng;
Du, Taiping;
Chen, Hao

Publication type:

Correction Notice

miRNA-30a-3p inhibits metastasis and enhances radiosensitivity in esophageal carcinoma by targeting insulin-like growth factor 1 receptor.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 1, p. 81, doi. 10.3892/mmr.2019.10222

By:

Fan, Yanxin;
Bian, Xiuhua;
Qian, Pudong;
Wen, Jing;
Yan, Pengwei;
Luo, Yanhong;
Wu, Jing;
Zhang, Qian

Publication type:

Article

Upregulated IGF-1 in the lungs of asthmatic mice originates from alveolar macrophages.

Published in:

Molecular Medicine Reports, 2019, v. 19, n. 2, p. 1266

By:

He, Jing;
Mu, Mimi;
Wang, Helong;
Ma, Hua;
Tang, Xu;
Fang, Qiang;
Guo, Shujun;
Song, Chuanwang

Publication type:

Article

MicroRNA‑539 inhibits cell proliferation, colony formation and invasion in pancreatic ductal adenocarcinoma by directly targeting IGF‑1R.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 2, p. 1804, doi. 10.3892/mmr.2018.9109

By:

Lin, Yongquan;
Rong, Lihua;
Zhao, Jingrong;
Lin, Ronghui;
Li, Shuhua

Publication type:

Article

MicroRNA‑381 inhibits cell proliferation and invasion in endometrial carcinoma by targeting the IGF‑1R.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 3, p. 4090, doi. 10.3892/mmr.2017.8288

By:

Tu, Chunhua;
Wang, FEN;
Wan, Junhui

Publication type:

Article

MicroRNA‑186 targets IGF‑1R and exerts tumor‑suppressing functions in glioma.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 5, p. 7821, doi. 10.3892/mmr.2017.7586

By:

JIAN JIANG;
WEIJIE WANG;
DAZHAO FANG;
XIAODONG JIN;
LIANSHU DING;
XIAOYANG SUN

Publication type:

Article

MicroRNA‑455 is downregulated in gastric cancer and inhibits cell proliferation, migration and invasion via targeting insulin‑like growth factor 1 receptor.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 3, p. 3664, doi. 10.3892/mmr.2017.6979

By:

SHAN ZHANG;
WAN‑LING YIN;
XIN ZHANG;
XIAO‑YU ZHANG

Publication type:

Article

Expression levels of microRNA‑455 and its potential functions by targeting IGF‑1R in melanoma.

Published in:

Molecular Medicine Reports, 2017, v. 15, n. 6, p. 3852, doi. 10.3892/mmr.2017.6468

By:

HUI WANG;
XIUJUAN SHAN;
LIANG YU

Publication type:

Article

GSK1904529A, an insulin-like growth factor-1 receptor inhibitor, inhibits glioma tumor growth, induces apoptosis and inhibits migration3.

Published in:

Molecular Medicine Reports, 2015, v. 12, n. 3, p. 3381, doi. 10.3892/mmr.2015.3869

By:

QIANG ZHOU;
JUNXIA ZHANG;
QINYING CUI;
XIAODONG LI;
GE GAO;
YANFEN WANG;
YUPING XU;
XIAOQUN GAO

Publication type:

Article

Cetuximab-induced insulin-like growth factor receptor I activation mediates cetuximab resistance in gastric cancer cells.

Published in:

Molecular Medicine Reports, 2015, v. 11, n. 6, p. 4547, doi. 10.3892/mmr.2015.3245

By:

XIN LI;
LING XU;
HEMING LI;
LEI ZHAO;
YING LUO;
ZHITU ZHU;
YUNPENG LIU;
XIUJUAN QU

Publication type:

Article

The IGF-1 Signaling Pathway in Viral Infections.

Published in:

Viruses (1999-4915), 2021, v. 13, n. 8, p. 1488, doi. 10.3390/v13081488

By:

Józefiak, Agata;
Larska, Magdalena;
Pomorska-Mól, Małgorzata;
Ruszkowski, Jakub J.

Publication type:

Article

Association of single nucleotide polymorphisms in genes coding insulin-like growth factor 1 system and milk production traits in Montbeliarde cows.

Published in:

South African Journal of Animal Science, 2016, v. 46, n. 2, p. 191, doi. 10.4314/sajas.v46i2.10

By:

Szewczuk, M.

Publication type:

Article

Combined Immunosuppressive Therapy for Severe Graves Dermopathy.

Published in:

2021

By:

Gubbi, Sriram;
Araque, Katherine Andrea;
Avadhanula, Shirisha;
Azam, Asma;
Merkel, Roxanne;
Cochran, Craig;
Burbelo, Peter Denis;
Waldman, Meryl;
Neumann, Susanne;
Gershengorn, Marvin Carl;
Skarulis, Monica;
Klubo-Gwiezdzinska, Joanna

Publication type:

Case Study

Insulin-Like Growth Factor Binding Protein-6 Promotes the Differentiation of Placental Mesenchymal Stem Cells into Skeletal Muscle Independent of Insulin-Like Growth Factor Receptor-1 and Insulin Receptor.

Published in:

Stem Cells International, 2019, p. 1, doi. 10.1155/2019/9245938

By:

Aboalola, Doaa;
Han, Victor K. M.

Publication type:

Article

Novel alternative splice variant of IGF-1R and its mRNA expression patterns in BaMa and Landrace pigs.

Published in:

Indian Journal of Animal Research, 2021, v. 55, n. 3, p. 271, doi. 10.18805/ijar.B-1107

By:

Rui Yang;
Lijie Dong;
Songcai Liu;
Yunyun Cheng;
Wenzhen Wei;
Jie Song;
Haoyang Li;
Hongwei Geng;
Linlin Hao;
Ying Zhang

Publication type:

Article

Expression of PAPP-A2 and IGF Pathway-Related Proteins in the Hip Joint of Normal Rat and Those with Developmental Dysplasia of the Hip.

Published in:

International Journal of Endocrinology, 2019, p. 1, doi. 10.1155/2019/7691531

By:

Chen, Yufan;
Lv, Haixiang;
Li, Lianyong;
Wang, Enbo;
Zhang, Lijun;
Zhao, Qun

Publication type:

Article

Metabotropic glutamate receptor 1 mediates melanocyte transformation via transactivation of insulin-like growth factor 1 receptor.

Published in:

Pigment Cell & Melanoma Research, 2014, v. 27, n. 4, p. 621, doi. 10.1111/pcmr.12237

By:

Teh, Jessica L. F.;
Shah, Raj;
Shin, Seung ‐ Shick;
Wen, Yu;
Mehnert, Janice M.;
Goydos, James;
Chen, Suzie

Publication type:

Article

Preclinical evaluation of Insulin-like growth factor receptor 1 (IGF1R) and Insulin Receptor (IR) as a therapeutic targets in triple negative breast cancer.

Published in:

PLoS ONE, 2023, v. 18, n. 3, p. 1, doi. 10.1371/journal.pone.0282512

By:

Roche, Sandra;
Gaule, Patricia;
Winrow, Deirdre;
Mukherjee, Nupur;
O'Neill, Fiona;
Conlon, Neil T.;
Meiller, Justine;
Collins, Denis M.;
Canonici, Alexandra;
Fawsi, Mohammed Ibrahim;
Estepa-Fernández, Alejandra;
Madden, Stephen F.;
Crown, John;
O'Donovan, Norma;
Eustace, Alex J.

Publication type:

Article

Identification of the possible therapeutic targets in the insulin-like growth factor 1 receptor pathway in a cohort of Egyptian hepatocellular carcinoma complicating chronic hepatitis C type 4.

Published in:

Drug Target Insights, 2020, v. 14, p. 1, doi. 10.33393/dti.2020.1548

By:

Mabrouk, Nada M. K.;
Elkaffash, Dalal M.;
Abdel-Hadi, Mona;
Abdelmoneim, Salah-ElDin;
ElDeen, Sameh Saad;
Gewaifel, Gihan;
Elella, Khaled A.;
Osman, Maher;
Baddour, Nahed

Publication type:

Article

Sex differences and left-right asymmetries in expression of insulin and insulin-like growth factor-1 receptors in developing rat hippocampus.

Published in:

Brain Structure & Function, 2012, v. 217, n. 2, p. 293, doi. 10.1007/s00429-011-0358-1

By:

Hami, Javad;
Sadr-Nabavi, Ariane;
Sankian, Mojtaba;
Haghir, Hossein

Publication type:

Article

Insulin receptor signaling mediates APP processing and β-amyloid accumulation without altering survival in a transgenic mouse model of Alzheimer's disease.

Published in:

Age (0161-9152), 2013, v. 35, n. 1, p. 83, doi. 10.1007/s11357-011-9333-2

By:

Stöhr, Oliver;
Schilbach, Katharina;
Moll, Lorna;
Hettich, Moritz;
Freude, Susanna;
Wunderlich, F.;
Ernst, Marianne;
Zemva, Johanna;
Brüning, Jens;
Krone, Wilhelm;
Udelhoven, Michael;
Schubert, Markus

Publication type:

Article

Insulin-Like Growth Factor II Targets the mTOR Pathway to Reverse Autism-Like Phenotypes in Mice.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 4, p. 1015, doi. 10.1523/JNEUROSCI.2010-17.2017

By:

Steinmetz, Adam B.;
Stern, Sarah A.;
Kohtz, Amy S.;
Descalzi, Giannina;
Alberini, Cristina M.

Publication type:

Article

Blocking IGF Signaling in Adult Neurons Alleviates Alzheimer's Disease Pathology through Amyloid-β Clearance.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 33, p. 11500, doi. 10.1523/JNEUROSCI.0343-15.2015

By:

Gontier, Géraldine;
George, Caroline;
Chaker, Zayna;
Holzenberger, Martin;
Aïd, Saba

Publication type:

Article

IGF-1 and Its Receptor in Esophageal Cancer: Association with Adenocarcinoma and Visceral Obesity.

Published in:

American Journal of Gastroenterology (Springer Nature), 2012, v. 107, n. 2, p. 196, doi. 10.1038/ajg.2011.417

By:

Doyle, Suzanne L;
Donohoe, Claire L;
Finn, Stephen P;
Howard, Julia M;
Lithander, Fiona E;
Reynolds, John V;
Pidgeon, Graham P;
Lysaght, Joanne

Publication type:

Article

Ghrelin and LEAP2: Subtle Players in Cachexia, Essential for the Bigger Picture.

Published in:

Endocrinology, 2025, v. 166, n. 7, p. 1, doi. 10.1210/endocr/bqaf093

By:

Lockie, Sarah H;
Hagg, Adam

Publication type:

Article

Mechanisms in Thyroid Eye Disease: The TSH Receptor Interacts Directly With the IGF-1 Receptor.

Published in:

Endocrinology, 2025, v. 166, n. 2, p. 1, doi. 10.1210/endocr/bqaf009

By:

Latif, Rauf;
Mezei, Mihaly;
Davies, Terry F

Publication type:

Article

The Emerging Role of the Fetal Insulin Receptor in Hormone-refractory Breast Cancer.

Published in:

Endocrinology, 2021, v. 162, n. 10, p. 1, doi. 10.1210/endocr/bqab147

By:

Mathur, Tanvi;
Yee, Douglas

Publication type:

Article