Works about IMMUNE checkpoint proteins

Results: 4901

Changing landscapes and increasing relevance of immunotherapy in localized MSI-H gastric adenocarcinoma.
Published in:
Expert Review of Clinical Pharmacology, 2024, v. 17, n. 12, p. 1093, doi. 10.1080/17512433.2024.2438178
By:
- Rogers, Jane E.;
- Ajani, Jaffer A.
Publication type:
Article
Cancer immunotherapy efficacy and machine learning.
Published in:
Expert Review of Anticancer Therapy, 2024, v. 24, n. 1/2, p. 21, doi. 10.1080/14737140.2024.2311684
By:
- Fang, Yuting;
- Chen, Xiaozhong;
- Cao, Caineng
Publication type:
Article
CAR-T cell technologies that interact with the tumour microenvironment in solid tumours.
Published in:
Expert Review of Clinical Immunology, 2024, v. 20, n. 8, p. 849, doi. 10.1080/1744666X.2024.2380894
By:
- Taylor, Chelsea Alice;
- Glover, Maya;
- Maher, John
Publication type:
Article
FLT3-mutated AML: immune evasion through exosome-mediated mechanisms and innovative combination therapies targeting immune escape.
Published in:
Expert Review of Anticancer Therapy, 2025, v. 25, n. 2, p. 143, doi. 10.1080/14737140.2025.2461632
By:
- Saadh, Mohamed J.;
- K. Abdulsahib, Waleed;
- Ashurova, Dilfuza;
- Sanghvi, Gaurav;
- Ballal, Suhas;
- Sharma, Rsk;
- Kumar Pathak, Piyus;
- Aman, Shankhyan;
- Kumar, Abhinav;
- Feez Sead, Fadhil;
- Chaitanya, M V N L
Publication type:
Article
Comparison of CD30L and OX40L Reveals CD30L as a Promising Therapeutic Target in Atopic Dermatitis.
Published in:
Allergy, 2025, v. 80, n. 2, p. 500, doi. 10.1111/all.16412
By:
- Gupta, Rinkesh K.;
- Figueroa, Daniela Salgado;
- Ay, Ferhat;
- Causton, Benjamin;
- Abdollahi, Shahla;
- Croft, Michael
Publication type:
Article
SIGLEC1 has the potential to be an immune-related prognostic indicator in colon adenocarcinoma: a study based on transcriptomic data and Mendelian randomization analysis.
Published in:
Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02093-2
By:
- Gu, Jue;
- Wang, Yaxuan;
- Zhang, Hui;
- Gu, Haijuan;
- Zhu, Haixia
Publication type:
Article
Pan-cancer analysis predicts MBOAT2 as a potential new ferroptosis related gene immune checkpoint.
Published in:
Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02078-1
By:
- Xie, Yuhan;
- Zhang, Shichao;
- Wu, Yu;
- Qi, Yuanjiong;
- Qi, Shiyong;
- Chen, Xiuju;
- Chen, Bing
Publication type:
Article
Bifunctional Metal–Organic Framework Synergistically Enhances Radiotherapy and Activates STING for Potent Cancer Radio‐Immunotherapy.
Published in:
Angewandte Chemie, 2025, v. 137, n. 5, p. 1, doi. 10.1002/ange.202417027
By:
- Wang, Chaoyu;
- Li, Jinhong;
- Jiang, Xiaomin;
- Ma, Xin;
- Zhen, Wenyao;
- Tillman, Langston;
- Weichselbaum, Ralph R.;
- Lin, Wenbin
Publication type:
Article
Significance of LRFN4 in prognosis and tumor microenvironment of lung adenocarcinoma.
Published in:
Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1540636
By:
- Wang, Nana;
- Cao, Shuming;
- Tan, Xiaofeng;
- Liu, Meirong
Publication type:
Article
Increased Co-Expression of PD-L1 and CTLA-4 Predicts Poor Overall Survival in Patients with Acute Myeloid Leukemia Following Allogeneic Hematopoietic Stem Cell Transplantation.
Published in:
ImmunoTargets & Therapy, 2025, v. 14, p. 25, doi. 10.2147/ITT.S500723
By:
- Chen, Cunte;
- Qiu, Kangjie;
- Chen, Jie;
- Wang, Shunqing;
- Zhang, Yuping;
- Wang, Caixia;
- Li, Yangqiu
Publication type:
Article
BUB1 serves as a biomarker for poor prognosis in liver hepatocellular carcinoma.
Published in:
BMC Immunology, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12865-025-00698-4
By:
- Zhang, Lili;
- Zhuge, Yuzheng;
- Ni, Jingbin
Publication type:
Article
Mesenchymal stem cell-derived extracellular vesicles alleviate autism by regulating microglial glucose metabolism reprogramming and neuroinflammation through PD-1/PD-L1 interaction.
Published in:
Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03250-z
By:
- Qin, Qian;
- Fan, Linlin;
- Zeng, Xin;
- Zheng, Danyang;
- Wang, Han;
- Li, Mengyue;
- Jiang, Yutong;
- Wang, Hui;
- Liu, Hao;
- Liang, Shengjun;
- Wu, Lijie;
- Liang, Shuang
Publication type:
Article
Effects of sex and obesity on immune checkpoint inhibition-related cardiac systolic dysfunction in aged mice.
Published in:
Basic Research in Cardiology, 2025, v. 120, n. 1, p. 207, doi. 10.1007/s00395-024-01088-4
By:
- Sayour, Nabil V.;
- Kucsera, Dániel;
- Alhaddad, Ayham R.;
- Tóth, Viktória É.;
- Gergely, Tamás G.;
- Kovács, Tamás;
- Hegedűs, Zsombor I.;
- Jakab, Márk E.;
- Ferdinandy, Péter;
- Varga, Zoltán V.
Publication type:
Article
Preclinical models of cardiotoxicity from immune checkpoint inhibitor therapy.
Published in:
Basic Research in Cardiology, 2025, v. 120, n. 1, p. 171, doi. 10.1007/s00395-024-01070-0
By:
- Buehning, Florian;
- Lerchner, Tobias;
- Vogel, Julia;
- Hendgen-Cotta, Ulrike B.;
- Totzeck, Matthias;
- Rassaf, Tienush;
- Michel, Lars
Publication type:
Article
Identification and functional characterization of T-cell exhaustion-associated lncRNA AL031775.1 in osteosarcoma: a novel therapeutic target.
Published in:
Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1517971
By:
- Wang, Yameng;
- Yuan, Jinghong;
- Guo, Keying;
- Zhang, Zhuoer;
- Zhu, Junchao;
- Arya, Shahrzad;
- Huang, Guowen;
- Li, Shengqin;
- Chen, Qi;
- Liu, Xijuan;
- Jia, Jingyu
Publication type:
Article
IFIT3: a crucial mediator in innate immunity and tumor progression with therapeutic implications.
Published in:
Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1515718
By:
- Wu, Rihan;
- Yang, Hao;
- Liu, Chunlei
Publication type:
Article
Interleukin-16 enhances anti-tumor immune responses by establishing a Th1 cell-macrophage crosstalk through reprogramming glutamine metabolism in mice.
Published in:
Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-57603-1
By:
- Wen, Zhenzhen;
- Liu, Tong;
- Xu, Xutao;
- Acharya, Nandini;
- Shen, Zhida;
- Lu, Yunkun;
- Xu, Junjie;
- Guo, Ke;
- Shen, Shuying;
- Zhao, Yuening;
- Wang, Pinli;
- Li, Shumin;
- Chen, Weiyu;
- Li, Hui;
- Ding, Yimin;
- Shang, Min;
- Guo, Hongshan;
- Hou, Yu;
- Cui, Bijun;
- Shen, Manlu
Publication type:
Article
Interleukin-6 as a Pan-Cancer Prognostic Inflammatory Biomarker: A Population-Based Study and Comprehensive Bioinformatics Analysis.
Published in:
Journal of Inflammation Research, 2025, v. 18, p. 573, doi. 10.2147/JIR.S484962
By:
- Xie, Hailun;
- Wei, Lishuang;
- Ruan, Guotian;
- Zhang, Heyang;
- Shi, Hanping
Publication type:
Article
Inflammation and Immune Escape in Ovarian Cancer: Pathways and Therapeutic Opportunities.
Published in:
Journal of Inflammation Research, 2025, v. 18, p. 895, doi. 10.2147/JIR.S503479
By:
- Liu, Chunyan;
- Yin, Qinan;
- Wu, Zhaoying;
- Li, Wenhui;
- Huang, Jun;
- Chen, Bo;
- Yang, Yanjun;
- Zheng, Xuewei;
- Zeng, Li;
- Wang, Jingjing
Publication type:
Article
MFAP4 is a novel prognostic biomarker in glioma correlating with immunotherapy resistance and ferroptosis.
Published in:
Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1551863
By:
- Lv, Yuanhao;
- Gao, Ying;
- Di, Wenyu;
- Li, Zhaoyi;
- Shi, Yashen;
- Hou, Tianyuan;
- Chen, Yiyang;
- Tian, Jiaqi;
- Xu, Miaoming;
- Su, Wei;
- Zhang, Min;
- Zhong, Jiateng
Publication type:
Article
Prognostic significance of the inhibitory-to-stimulatory immune checkpoint ratio in patients with breast cancer.
Published in:
Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1524861
By:
- Tang, Chuangang;
- Hu, Xiang;
- Hao, Dawei;
- Chen, Tao;
- Wang, Pei;
- Li, Changwen;
- Chen, Chengling;
- Li, Yongcheng;
- Hao, Xiaowen;
- Yuan, Zeng
Publication type:
Article
Unveiling ac4C modification pattern: a prospective target for improving the response to immunotherapeutic strategies in melanoma.
Published in:
Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06297-6
By:
- Liu, Jianlan;
- Zhang, Pengpeng;
- Wu, Chaoqin;
- Luo, Binlin;
- Cao, Xiaojian;
- Tang, Jian
Publication type:
Article
Injectable celastrol-loading emulsion hydrogel for immunotherapy of low-immunogenic cancer.
Published in:
Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03154-y
By:
- Liu, Yu;
- Zhang, Jia;
- Lai, Chunyu;
- Wang, Wenjun;
- Huang, Yangyue;
- Bao, Xuanwen;
- Yan, Haimeng;
- Sun, Xuqi;
- Liu, Qiqi;
- Chen, Dong;
- Dai, Xiaomeng;
- Qian, Xinyu;
- Zhao, Peng
Publication type:
Article
SPP1 as a Prognostic and Immunotherapeutic Biomarker in Gliomas and Other Cancer Types: A Pan-Cancer Study.
Published in:
Journal of Inflammation Research, 2025, v. 18, p. 2247, doi. 10.2147/JIR.S505237
By:
- Wang, Kan;
- Wan, Jinxin;
- Zheng, Ruipeng;
- Xiao, Yifei;
- Lv, Fengjun;
- Ge, Haitao;
- Yang, Guang;
- Cheng, Yu
Publication type:
Article
Single-Cell RNA Sequencing Reveals Peripheral Immune Cell Senescence and Inflammatory Phenotypes in Patients with Premature Ovarian Failure.
Published in:
Journal of Inflammation Research, 2025, v. 18, p. 2699, doi. 10.2147/JIR.S496130
By:
- Liu, Jianan;
- Wang, Li;
- Zhong, Weijun;
- Cai, Jing;
- Sun, Yan;
- Li, SongJun;
- Li, Jiayi;
- Liu, Yanhui;
- Xiong, Fu
Publication type:
Article
Weighted Gene Coexpression Network Analysis Identifies Neutrophil-Related Molecular Subtypes and Their Clinical Significance in Gastric Cancer.
Published in:
Cancer Management & Research, 2025, v. 17, p. 397, doi. 10.2147/CMAR.S500215
By:
- Chen, Chujia;
- Shao, Yongfu;
- Ye, Chengyuan;
- Yu, Xuan;
- Hu, Meng;
- Yan, Jianing;
- Ye, Guoliang
Publication type:
Article
A blood-based liquid biopsy analyzing soluble immune checkpoints and cytokines identifies distinct neuroendocrine tumors.
Published in:
Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03337-3
By:
- Mata-Martínez, Pablo;
- Celada, Lucía;
- Cueto, Francisco J.;
- Sáenz de Santa María, Gonzalo;
- Fernández, Jaime;
- Terrón-Arcos, Verónica;
- Valdés, Nuria;
- Moreira, Vanesa García;
- del Toro, María Isabel Enguita;
- López-Collazo, Eduardo;
- Chiara, María-Dolores;
- del Fresno, Carlos
Publication type:
Article
Multiple mechanisms and applications of tertiary lymphoid structures and immune checkpoint blockade.
Published in:
Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03318-6
By:
- Li, Zelin;
- Liu, Shuhan;
- Liu, Deyu;
- Yang, Kangping;
- Xiong, Jing;
- Fang, Ziling
Publication type:
Article
Human endogenous retrovirus-H long terminal repeat-associating 2: an emerging immune checkpoint for cancer immunotherapy.
Published in:
Journal of Leukocyte Biology, 2025, v. 117, n. 2, p. 1, doi. 10.1093/jleuko/qiae158
By:
- Cao, Zeya;
- Wang, Youping;
- Cheng, Shih-Chin;
- He, Nanhai
Publication type:
Article
Successful treatment of immune checkpoint inhibitor-associated fulminant myocarditis with abatacept and ruxolitinib: a case report.
Published in:
European Heart Journal Case Reports, 2025, v. 9, n. 2, p. 1, doi. 10.1093/ehjcr/ytaf019
By:
- Wadden, Elena;
- Lai, Carol;
- Grivas, Petros;
- Bhatia, Shailender;
- Portuguese, Andrew J;
- Salem, Joe-Elie;
- Moslehi, Javid J;
- Cheng, Richard K
Publication type:
Article
Targeting GOLPH3L improves glioblastoma radiotherapy by regulating STING-NLRP3–mediated tumor immune microenvironment reprogramming.
Published in:
Science Translational Medicine, 2025, v. 17, n. 788, p. 1, doi. 10.1126/scitranslmed.ado0020
By:
- Sun, Shuo;
- Qian, Shiyu;
- Wang, Ran;
- Zhao, Mengya;
- Li, Ran;
- Gu, Wei;
- Zhao, Mengjie;
- Qian, Chunfa;
- Liu, Liang;
- Tang, Xianglong;
- Li, Yangyang;
- Shi, Hui;
- Pan, Yunsong;
- Xiao, Hong;
- Yang, Kun;
- Hu, Chupeng;
- Huang, Yedi;
- Wei, Liangnian;
- Zhang, Yuhan;
- Ji, Jing
Publication type:
Article
Post-translational modifications in hepatocellular carcinoma: unlocking new frontiers in immunotherapy.
Published in:
Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1554372
By:
- Piao, Yuexian;
- Zhai, Naicui;
- Zhang, Xiaoling;
- Zhao, Wenjie;
- Li, Min
Publication type:
Article
Polyamine metabolism and anti-tumor immunity.
Published in:
Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1529337
By:
- Wu, Jing-Yi;
- Zeng, Yan;
- You, Yu-Yang;
- Chen, Qi-Yue
Publication type:
Article
Capsanthin inhibits migration and reduces N-linked glycosylation of PD-L1 via the EZH2-PD-L1 axis in triple-negative breast cancer brain metastasis.
Published in:
Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02368-1
By:
- Chien, Yi-Chung;
- Wu, Jia-Yan;
- Liu, Liang-Chih;
- Yu, Yung-Luen
Publication type:
Article
m6A epitranscriptomic modification in hepatocellular carcinoma: implications for the tumor microenvironment and immunotherapy.
Published in:
Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1538658
By:
- Liu, Fen;
- Liu, Qingbin;
- Li, Xianying;
- Wang, Yufei;
- Cao, Ruoyu;
- Zhang, Shiyu;
- Jiang, Shulong;
- Wu, Jianlin
Publication type:
Article
Aptamer based immunotherapy: a potential solid tumor therapeutic.
Published in:
Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1536569
By:
- Mathavan, Sarmilah;
- Tam, Yew Joon;
- Mustaffa, Khairul Mohd Fadzli;
- Tye, Gee Jun
Publication type:
Article
Vascular E-selectin Expression Recognized by the U12-12 Monoclonal Antibody as a Predictive Marker for Steroid Resistance in Immune Checkpoint Inhibitor-related Colitis.
Published in:
Journal of Histochemistry & Cytochemistry, 2025, v. 73, n. 1/2, p. 81, doi. 10.1369/00221554251320703
By:
- Nakashima, Koki;
- Nagaya, Tadanobu;
- Iwaya, Mai;
- Hiramatsu, Katsushi;
- Uehara, Takeshi;
- Nakamoto, Yasunari;
- Ishizuka, Tamotsu;
- Kobayashi, Motohiro
Publication type:
Article
A bibliometric and visualization analysis of the role of traditional Chinese medicine in cancer immunotherapy.
Published in:
Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1499026
By:
- Lian, Yixiao;
- Sun, Jie;
- Yang, Lin;
- Yu, Weidong
Publication type:
Article
Effects of c-Kit Receptor, AKT, and NF-κB Inhibitors on Immune Evasion in Multiple Myeloma Cells.
Published in:
Iranian Journal of Allergy, Asthma & Immunology, 2025, v. 24, n. 1, p. 89, doi. 10.18502/ijaai.v24i1.18024
By:
- Ranjbar, Abbas;
- Taghiloo, Saeid;
- Nozari, Parvin;
- Hedayatizadeh-Omran, Akbar;
- Asgarian-Omran, Hossein
Publication type:
Article
Targeting Metabolic Vulnerabilities to Combat Drug Resistance in Cancer Therapy.
Published in:
Journal of Personalized Medicine, 2025, v. 15, n. 2, p. 50, doi. 10.3390/jpm15020050
By:
- Khan, Taranatee;
- Nagarajan, Manojavan;
- Kang, Irene;
- Wu, Chunjing;
- Wangpaichitr, Medhi
Publication type:
Article
Prognostic Biomarkers in Isocitrate Dehydrogenase Wild-Type Glioblastoma: A Focus on B7-H3.
Published in:
Brain Sciences (2076-3425), 2025, v. 15, n. 2, p. 212, doi. 10.3390/brainsci15020212
By:
- Yüceer, Ramazan Oğuz;
- Kaya, Seyhmus;
- Balcı, Sema Nur;
- Eğilmez, Hatice Reyhan;
- Yılmaz, Mukaddes;
- Erdıs, Eda
Publication type:
Article
Lipid-siRNA Conjugates Targeting High PD-L1 Expression as Potential Novel Immune Checkpoint Inhibitors.
Published in:
Biomolecules (2218-273X), 2025, v. 15, n. 2, p. 293, doi. 10.3390/biom15020293
By:
- Tansou, Rina;
- Kubo, Takanori;
- Nishida, Haruka;
- Nishimura, Yoshio;
- Mihara, Keichiro;
- Yanagihara, Kazuyoshi;
- Seyama, Toshio
Publication type:
Article
Ubiquitin-Specific Protease Inhibitors for Cancer Therapy: Recent Advances and Future Prospects.
Published in:
Biomolecules (2218-273X), 2025, v. 15, n. 2, p. 240, doi. 10.3390/biom15020240
By:
- Bakkar, Mohamad;
- Khalil, Sara;
- Bhayekar, Komal;
- Kushwaha, Narva Deshwar;
- Samarbakhsh, Amirreza;
- Dorandish, Sadaf;
- Edwards, Holly;
- Dou, Q. Ping;
- Ge, Yubin;
- Gavande, Navnath S.
Publication type:
Article
Targeting the PARylation-Dependent Ubiquitination Signaling Pathway for Cancer Therapies.
Published in:
Biomolecules (2218-273X), 2025, v. 15, n. 2, p. 237, doi. 10.3390/biom15020237
By:
- Huang, Daoyuan;
- Wang, Jingchao;
- Chen, Li;
- Jiang, Weiwei;
- Inuzuka, Hiroyuki;
- Simon, David K.;
- Wei, Wenyi
Publication type:
Article
UVC-Induced Oxidative Stress and DNA Damage Repair Status in Head and Neck Squamous Cell Carcinoma Patients with Different Responses to Nivolumab Therapy.
Published in:
Biology (2079-7737), 2025, v. 14, n. 2, p. 195, doi. 10.3390/biology14020195
By:
- Papanikolaou, Christina;
- Economopoulou, Panagiota;
- Gavrielatou, Niki;
- Mavroeidi, Dimitra;
- Psyrri, Amanda;
- Souliotis, Vassilis L.
Publication type:
Article
Extracellular Vesicle-Based Strategies for Tumor Immunotherapy.
Published in:
Pharmaceutics, 2025, v. 17, n. 2, p. 257, doi. 10.3390/pharmaceutics17020257
By:
- Jiramonai, Luksika;
- Liang, Xing-Jie;
- Zhu, Mengliang
Publication type:
Article
Intestinal Probiotic Lysate Modified Bifunctional Nanoparticle for Efficient Colon Cancer Immunotherapy.
Published in:
Pharmaceutics, 2025, v. 17, n. 2, p. 139, doi. 10.3390/pharmaceutics17020139
By:
- Zhu, Manfang;
- Chen, Hongkui;
- Chen, Xiaohua;
- Zhang, Yueyang;
- Chen, Xiayu;
- Zhou, Bailing;
- Duan, Xingmei;
- Zhou, Na;
- Zhang, Xin
Publication type:
Article
Retinol-Binding Protein 4 as a Biomarker in Cancer: Insights from a Pan-Cancer Analysis of Expression, Immune Infiltration, and Methylation.
Published in:
Genes, 2025, v. 16, n. 2, p. 150, doi. 10.3390/genes16020150
By:
- Zhao, Jia;
- Liu, Yaxin;
- Zhou, Lingqin;
- Liu, Yi
Publication type:
Article
Exploring the application of metal-based photothermal agents in photothermal therapy combined with immune checkpoint therapy.
Published in:
Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1553158
By:
- Xie, Bin;
- Xiao, ZhiRong;
- Ling, JiaBao;
- Peng, Yichao;
- Chen, Tianfeng
Publication type:
Article
Assessing the Clinical Relevance of Soluble PD-1 and PD-L1: A Multi-Cohort Study Across Diverse Tumor Types and Prognostic Implications.
Published in:
Biomedicines, 2025, v. 13, n. 2, p. 500, doi. 10.3390/biomedicines13020500
By:
- Kushlinskii, Nikolay E.;
- Kovaleva, Olga V.;
- Gratchev, Alexei N.;
- Alferov, Alexander A.;
- Kuzmin, Yurii B.;
- Sokolov, Nikolai Y.;
- Tsekatunov, Dmitry A.;
- Ryzhavskaya, Irina B.;
- Kuznetsov, Igor N.;
- Kushlinskii, Dmitry N.;
- Mamedli, Zaman Z.;
- Stilidi, Ivan S.
Publication type:
Article