Works about HUNTINGTON disease

Results: 5000

Cell-specific mechanisms drive connectivity across the time course of Huntington's disease.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60556-0

By:

Estevez-Fraga, Carlos;
Sebenius, Isaac;
Hansen, Justine Y.;
Hänisch, Benjamin;
Zeun, Paul;
Scahill, Rachael I.;
Gregory, Sarah;
Johnson, Eilanoir B.;
Wild, Edward J.;
Byrne, Lauren M.;
Durr, Alexandra;
Landwehrmeyer, Bernhard;
Leavitt, Blair R.;
Misic, Bratislav;
Valk, Sofie Louise;
Rees, Geraint;
Tabrizi, Sarah J.;
McColgan, Peter

Publication type:

Article

Inhibition of class IIa HDACs reduces mutant HTT aggregation by affecting RNA stability.

Published in:

Frontiers in Molecular Neuroscience, 2025, p. 1, doi. 10.3389/fnmol.2025.1579194

By:

Reisbitzer, Annika;
Hollitzer, Cecilia;
Geraci, Adriana;
Schaefer, Jessye;
Burghaus, Maximilian;
Bruns, Jonas;
Urban, Joachim;
Kurz, Thomas;
Krauß, Sybille

Publication type:

Article

Current perspectives on gene therapy and its involvement in curing genetic disorders.

Published in:

Human Genetics, 2025, v. 144, n. 7, p. 695, doi. 10.1007/s00439-025-02757-7

By:

Nishad, Shireen;
Dongare, Dipali;
Saha, Sayani;
Anil, Raskar Dhanashri;
Srivastava, Nidhi;
Dey, Abhishek

Publication type:

Article

Barbigerone attenuates 3-nitropropionic acid-induced Huntington's disease-like neuropathology in rats via antioxidant, anti-inflammatory, and neuroprotective mechanisms.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-07181-5

By:

Alenezi, Sattam Khulaif

Publication type:

Article

Genomic ncRNAs regulating mitochondrial function in neurodegeneration: a neglected clue in the complex etiopathogenesis of multiple sclerosis.

Published in:

Cell & Bioscience, 2025, v. 15, n. 1, p. 1, doi. 10.1186/s13578-025-01438-2

By:

Sanadgol, Nima;
Samadi, Mahedeh;
Voelz, Clara;
Khalseh, Roghayeh;
Amini, Javad;
Beyer, Cordian;
Kipp, Markus;
Clarner, Tim

Publication type:

Article

Nonlinear characteristics of gait signals in neurodegenerative diseases.

Published in:

Frontiers in Neurology, 2025, p. 1, doi. 10.3389/fneur.2025.1607273

By:

Yue, Yang;
Chang, Na;
Shi, Zonglin

Publication type:

Article

The Retinal Dopaminergic Circuit as a Biomarker for Huntington's and Alzheimer's Diseases.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5532, doi. 10.3390/ijms26125532

By:

Blanco-Hernán, Pedro;
Aguado, Lorena;
Asensio, María José;
Gómez-Soria, Ana;
de la Villa, Pedro;
Casarejos, María José;
Mansilla, Alicia

Publication type:

Article

Identification of markers for neurescence through transcriptomic profiling of postmortem human brains.

Published in:

NPJ Aging, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41514-025-00235-y

By:

Dehkordi, Shiva Kazempour;
Sajedi, Sogand;
Heshmat, Amirreza;
Orr, Miranda E.;
Zare, Habil

Publication type:

Article

Significant underascertainment in Huntington's disease Open Access.

Published in:

Brain Communications, 2025, v. 7, n. 3, p. 1, doi. 10.1093/braincomms/fcaf194

By:

Lee, Sujin;
Weisburd, Ben;
Lee, Jiwoo;
Correia, Kevin;
Zeng, Sophia;
Park, Seri S;
Shin, Jun Wan;
Choi, Doo Eun;
Kim, Kyung-Hee;
Jang, Jae-Hyun;
Gillis, Tammy;
Rehm, Heidi L;
Gusella, James F;
MacDonald, Marcy E;
Lee, Jong-Min

Publication type:

Article

Highlights from the Brain Conference 2025 Open Access.

Published in:

Brain Communications, 2025, v. 7, n. 3, p. 1, doi. 10.1093/braincomms/fcaf143

By:

Marescotti, Manuela

Publication type:

Article

In Vitro Efficacy of PEI-Derived Lipopolymers in Silencing of Toxic Proteins in a Neuronal Model of Huntington's Disease.

Published in:

Pharmaceutics, 2025, v. 17, n. 6, p. 726, doi. 10.3390/pharmaceutics17060726

By:

Morales, Luis C.;
Modi, Luv;
Abbasi Dezfouli, Saba;
Rajendran, Amarnath Praphakar;
Kc, Remant;
Kadam, Vaibhavi;
Sipione, Simonetta;
Uludağ, Hasan

Publication type:

Article

Multitarget Compounds Designed for Alzheimer, Parkinson, and Huntington Neurodegeneration Diseases.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 831, doi. 10.3390/ph18060831

By:

Katsoulaki, Eleftheria-Emmanouela;
Dimopoulos, Dimitrios;
Hadjipavlou-Litina, Dimitra

Publication type:

Article

Two Decades of Huntington's Disease in Varna, Bulgaria: A Retrospective Single-Centre Study of Clinical Trends and Challenges.

Published in:

Neurology International, 2025, v. 17, n. 6, p. 95, doi. 10.3390/neurolint17060095

By:

Levkova, Mariya;
Tsalta-Mladenov, Mihael;
Stoyanova, Milena;
Hachmeriyan, Mari;
Angelova, Lyudmila;
Kaprelyan, Ara

Publication type:

Article

Dementia research in India: A scientometric analysis of research output during 2002-11.

Published in:

Annals of Library & Information Studies, 2012, v. 59, n. 4, p. 280

By:

Gupta, B. M.;
Kaur, Har;
Kshitig, Avinash

Publication type:

Article

Koroner Bypass Ameliyatı Geçiren Hastalarda Deliryum Gelişiminin Nitrik Oksit Düzeyleriyle İlişkisi.

Published in:

Klinik Psikofarmakoloji Bulteni, 2004, v. 14, n. 4, p. 185

By:

Sezer, Özlem;
Karlidağ, Rifat;
Karabulut, Aysun Bay;
Özcan, Cemal;
Nisanoğlu, Vedat;
Türköz, Yusuf;
But, Abdulkadir;
Ünal, Süheyla

Publication type:

Article

Understanding the Implications of a Complete Case Analysis for Regression Models with a Right-Censored Covariate.

Published in:

American Statistician, 2024, v. 78, n. 3, p. 335, doi. 10.1080/00031305.2023.2282629

By:

Ashner, Marissa C.;
Garcia, Tanya P.

Publication type:

Article

Huntingtin Is Required for Epithelial Polarity through RAB11A-Mediated Apical Trafficking of PAR3-aPKC.

Published in:

PLoS Biology, 2015, v. 13, n. 5, p. 1, doi. 10.1371/journal.pbio.1002142

By:

Elias, Salah;
McGuire, John Russel;
Yu, Hua;
Humbert, Sandrine

Publication type:

Article

The Wnt Receptor Ryk Reduces Neuronal and Cell Survival Capacity by Repressing FOXO Activity During the Early Phases of Mutant Huntingtin Pathogenicity.

Published in:

PLoS Biology, 2014, v. 12, n. 6, p. 1, doi. 10.1371/journal.pbio.1001895

By:

Tourette, Cendrine;
Farina, Francesca;
Vazquez-Manrique, Rafael P.;
Orfila, Anne-Marie;
Voisin, Jessica;
Hernandez, Sonia;
Offner, Nicolas;
Parker, J. Alex;
Menet, Sophie;
Kim, Jinho;
Lyu, Jungmok;
Choi, Si Ho;
Cormier, Kerry;
Edgerly, Christina K.;
Bordiuk, Olivia L.;
Smith, Karen;
Louise, Anne;
Halford, Michael;
Stacker, Steven;
Vert, Jean-Philippe

Publication type:

Article

An HDAC in the Cytoplasm, not the Nucleus, Plays a Pathogenic Role in Huntington's Disease.

Published in:

PLoS Biology, 2013, v. 11, n. 11, p. 1, doi. 10.1371/journal.pbio.1001718

By:

Robinson, Richard

Publication type:

Article

HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration.

Published in:

PLoS Biology, 2013, v. 11, n. 11, p. 1, doi. 10.1371/journal.pbio.1001717

By:

Mielcarek, Michal;
Landles, Christian;
Weiss, Andreas;
Bradaia, Amyaouch;
Seredenina, Tamara;
Inuabasi, Linda;
Osborne, Georgina F.;
Wadel, Kristian;
Touller, Chrystelle;
Butler, Rachel;
Robertson, Janette;
Franklin, Sophie A.;
Smith, Donna L.;
Park, Larry;
Marks, Paul A.;
Wanker, Erich E.;
Olson, Eric N.;
Luthi-Carter, Ruth;
van der Putten, Herman;
Beaumont, Vahri

Publication type:

Article

Histone Deacetylase Complexes Promote Trinucleotide Repeat Expansions.

Published in:

PLoS Biology, 2012, v. 10, n. 2, p. 1, doi. 10.1371/journal.pbio.1001257

By:

Debacker, Kim;
Frizzell, Aisling;
Gleeson, Olive;
Kirkham-McCarthy, Lucy;
Mertz, Tony;
Lahue, Robert S.

Publication type:

Article

Modulation of Heat Shock Transcription Factor 1 as a Therapeutic Target for Small Molecule Intervention in Neurodegenerative Disease.

Published in:

PLoS Biology, 2010, v. 8, n. 1, p. 1, doi. 10.1371/journal.pbio.1000291

By:

Neef, Daniel W.;
Turski, Michelle L.;
Thiele, Dennis J.

Publication type:

Article

Functional Amyloid Formation within Mammalian Tissue.

Published in:

PLoS Biology, 2006, v. 4, n. 1, p. e6, doi. 10.1371/journal.pbio.0040006

By:

Fowler, Douglas M.;
Koulov, Atanas V.;
Alory-Jost, Christelle;
Marks, Michael S.;
Balch, William E.;
Kelly, Jeffery W.

Publication type:

Article

Functional Amyloid Formation within Mammalian Tissue.

Published in:

PLoS Biology, 2005, v. 3, n. 11, p. 1, doi. 10.1371/journal.pbio.0040006

By:

Fowler, Douglas M;
Koulov, Atanas V;
Alory-Jost, Christelle;
Marks, Michael S;
Balch, William E;
Kelly, Jeffery W

Publication type:

Article

Evolving Motivations: Patients’ and Caregivers’ Perceptions About Seeking Myotonic Dystrophy (DM1) and Huntington’s Disease Care.

Published in:

Qualitative Health Research, 2017, v. 27, n. 11, p. 1727, doi. 10.1177/1049732317711901

By:

LaDonna, Kori A.;
Watling, Christopher J.;
Ray, Susan L.;
Piechowicz, Christine;
Venance, Shannon L.

Publication type:

Article

Risperidone long-acting injection in Huntington's disease.

Published in:: Brown University Psychopharmacology Update, 2011, v. 22, n. 2, p. 8
Publication type:: Article

Biglycan protects human neuroblastoma cells from nitric oxide-induced death by inhibiting AMPK-mTOR mediated autophagy and intracellular ROS level.

Published in:

Biotechnology Letters, 2020, v. 42, n. 4, p. 657, doi. 10.1007/s10529-020-02818-z

By:

Chen, Sujuan;
Guo, Dandan;
Lei, Bingbing;
Bi, Jiajia;
Yang, Haijie

Publication type:

Article

miR-34a-5p as molecular hub of pathomechanisms in Huntington's disease.

Published in:

Molecular Medicine, 2023, v. 29, n. 1, p. 1, doi. 10.1186/s10020-023-00640-7

By:

Hart, Martin;
Diener, Caroline;
Lunkes, Laetitia;
Rheinheimer, Stefanie;
Krammes, Lena;
Keller, Andreas;
Meese, Eckart

Publication type:

Article

From Mad Cows to Neurotic Yeast: Novel Molecular Approaches to Understand Neurodegeneration.

Published in:: Microscopy & Microanalysis, 2008, v. 14, n. 0, p. 105, doi. 10.1017/S143192760808954X
Publication type:: Article

From Mad Cows to Neurotic Yeast: Novel Molecular Approaches to Understand Neurodegeneration.

Published in:

Microscopy & Microanalysis, 2008, v. 14, n. S3, p. 105, doi. 10.1017/S143192760808954X

By:

Outeiro, T.F.

Publication type:

Article

Oxidative/Nitrosative Stress, Apoptosis, and Redox Signaling: Key Players in Neurodegenerative Diseases.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 1, p. 1, doi. 10.1002/jbt.70133

By:

Üremiş, Nuray;
Üremiş, Muhammed Mehdi

Publication type:

Article

Multimodal action of phosphodiesterase 5 inhibitors against neurodegenerative disorders: An update review.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 11, p. 1, doi. 10.1002/jbt.70021

By:

Singh, Niraj Kumar;
Singh, Pranjul;
Varshney, Prachi;
Singh, Ashini;
Bhushan, Bharat

Publication type:

Article

Neuroprotective effect of quercetin against rotenone‐induced neuroinflammation and alterations in mice behavior.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 10, p. 1, doi. 10.1002/jbt.23165

By:

Jain, Juli;
Hasan, Whidul;
Biswas, Pronit;
Yadav, Rajesh S.;
Jat, Deepali

Publication type:

Article

Limbic system pathologies associated with deficiencies and excesses of the trace elements iron, zinc, copper, and selenium.

Published in:

Nutrition Reviews, 2012, v. 70, n. 12, p. 679, doi. 10.1111/j.1753-4887.2012.00521.x

By:

Torres-Vega, Adriana;
Pliego-Rivero, Bernardo F;
Otero-Ojeda, Gloria A;
Gómez-Oliván, Leobardo M;
Vieyra-Reyes, Patricia

Publication type:

Article

Versatility of the Mec1<sup>ATM/ATR</sup> signaling network in mediating resistance to replication, genotoxic, and proteotoxic stresses.

Published in:

Current Genetics, 2019, v. 65, n. 3, p. 657, doi. 10.1007/s00294-018-0920-y

By:

Corcoles-Saez, Isaac;
Dong, Kangzhen;
Cha, Rita S.

Publication type:

Article

Validation of prognostic stroke scores—comments on "Evaluation of FRESH scores in predicting outcome and quality of life after aneurysmal subarachnoid haemorrhage in a European patient cohort": Author's response.

Published in:

Acta Neurochirurgica, 2024, v. 166, n. 1, p. 1, doi. 10.1007/s00701-024-05909-2

By:

Hofmann, Björn B.;
Kram, Rainer;
Beseoglu, Kerim;
Cornelius, Jan F.

Publication type:

Article

Establishment and maintenance of an R6/1 transgenic mouse colony and validation of its progressive neurological phenotype to study Huntington's disease.

Published in:

Veterinaria México OA, 2018, v. 5, n. 1, p. 1, doi. 10.21753/vmoa.5.1.487

By:

García-Lara, Lucia;
Morales-Martínez, Adriana;
Angeles-López, Quetzalli D.;
Pedraza-Espitia, Hilda;
Pérez-Neri, Iván;
Rodríguez-Balderas, Cesar A.;
Pérez-Severiano, Francisca

Publication type:

Article

The role of oxidative stress in neurodegenerative diseases and potential antioxidant therapies.

Published in:

Advances in Laboratory Medicine / Avances en Medicina de Laboratorio, 2022, v. 3, n. 4, p. 342, doi. 10.1515/almed-2022-0111

By:

Sienes Bailo, Paula;
Llorente Martín, Elena;
Calmarza, Pilar;
Montolio Breva, Silvia;
Bravo Gómez, Adrián;
Pozo Giráldez, Adela;
Sánchez-Pascuala Callau, Joan J.;
Vaquer Santamaría, Juana M.;
Dayaldasani Khialani, Anita;
Cerdá Micó, Concepción;
Camps Andreu, Jordi;
Sáez Tormo, Guillermo;
Fort Gallifa, Isabel

Publication type:

Article

Primary health care professionals' experiences with caring for patients with advanced Huntington's disease: a qualitative study.

Published in:

BMC Primary Care, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12875-024-02408-2

By:

van Walsem, Marleen R.;
Howe, Emilie I.;
Andelic, Nada;
Frich, Jan C.

Publication type:

Article

Pathogenesis of Neurodegenerative Diseases and the Protective Role of Natural Bioactive Components.

Published in:

Journal of the American Nutrition Association, 2024, v. 43, n. 1, p. 20, doi. 10.1080/27697061.2023.2203235

By:

Samanta, Saptadip;
Chakraborty, Sanjoy;
Bagchi, Debasis

Publication type:

Article

Can a Micronutrient Mixture Delay the Onset and Progression of Symptoms of Single-Point Mutation Diseases?

Published in:

Journal of the American Nutrition Association, 2022, v. 41, n. 5, p. 489, doi. 10.1080/07315724.2021.1910592

By:

Prasad, Kedar N.;
Bondy, Stephen C.

Publication type:

Article

Author Index Volume 24 (2025).

Published in:: Journal of Computational Biophysics & Chemistry, 2025, v. 24, n. 10, p. 1457, doi. 10.1142/S2737416525990017
Publication type:: Article

Exploring the Genetic and Molecular Connection between Autism and Huntington's Disease via Transcriptomics and Biological Interaction Networks Analysis.

Published in:

Journal of Computational Biophysics & Chemistry, 2025, v. 24, n. 2, p. 215, doi. 10.1142/S2737416524500583

By:

Naveed, Muhammad;
Cheema, Sana Rehman;
Aziz, Tariq;
Makhdoom, Syeda Izma;
Saleem, Urooj;
Jamil, Hamza;
Alhomrani, Majid;
Alsanie, Walaa F.;
Alamri, Abdulhakeem S.

Publication type:

Article

Neuroprotective Effect of Ethanolic Extract of Pedalium murex Linn Leaf in 3-Nitropropionic acid Induced Neurodegeneration.

Published in:

Journal of Research in Pharmacy, 2023, v. 27, n. 4, p. 1388, doi. 10.29228/jrp.426

By:

VELAYUTHAM, Suresh;
Sundararaju, Arunprasanth;
GOVINDHASWAMY, Thamotharan;
Gurupackiyam, Muthukumaran;
Balakrishnan, Anbukarasi;
ABDUL, Mohamed Yasar;
ASHOK, Chetan;
JEYABALAN, Srikanth

Publication type:

Article

Neuroprotective Effect of Ethanolic Extract of Pedalium murex Linn Leaf in 3-Nitropropionic acid Induced Neurodegeneration.

Published in:

Journal of Research in Pharmacy, 2023, v. 27, n. 3, p. 1143, doi. 10.29228/jrp.405

By:

VELAYUTHAM, Suresh;
SUNDARARAJU, Arunprasanth;
GOVINDHASWAMY, Thamotharan;
GURUPACKIYAM, Muthukumaran;
BALAKRISHNAN, Anbukarasi;
ABDUL, Mohamed Yasar;
ASHOK, Chetan;
JEYABALAN, Srikanth

Publication type:

Article

PRZEGLĄD PIŚMIENNICTWA.

Published in:

Polski Przegląd Neurologiczny, 2024, v. 20, n. 3, p. 203, doi. 10.5603/ppn.103450

By:

Marschollek, Karol

Publication type:

Article

SUPT4H1-edited stem cell therapy rescues neuronal dysfunction in a mouse model for Huntington's disease.

Published in:

NPJ Regenerative Medicine, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41536-021-00198-0

By:

Park, Hyun Jung;
Han, Areum;
Kim, Ji Yeon;
Choi, Jiwoo;
Bae, Hee Sook;
Cho, Gyu-bon;
Shin, Hyejung;
Shin, Eun ji;
Lee, Kang-in;
Kim, Seokjoong;
Lee, Jae Young;
Song, Jihwan

Publication type:

Article

SUPT4H1-edited stem cell therapy rescues neuronal dysfunction in a mouse model for Huntington's disease.

Published in:

NPJ Regenerative Medicine, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41536-021-00198-0

By:

Park, Hyun Jung;
Han, Areum;
Kim, Ji Yeon;
Choi, Jiwoo;
Bae, Hee Sook;
Cho, Gyu-bon;
Shin, Hyejung;
Shin, Eun ji;
Lee, Kang-in;
Kim, Seokjoong;
Lee, Jae Young;
Song, Jihwan

Publication type:

Article

Impact of Upper Limb Function on Activities of Daily Living and Quality of Life in Huntington's Disease.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 1, p. 168, doi. 10.3390/jcm14010168

By:

Simón-Vicente, Lucía;
Rivadeneyra, Jéssica;
Mariscal, Natividad;
Aguado, Laura;
Miguel-Pérez, Irene;
Saiz-Rodríguez, Miriam;
García-Bustillo, Álvaro;
Muñoz-Siscart, Ignacio;
Díaz-Piñeiro, Dolores;
Cubo, Esther

Publication type:

Article

Early Diagnosis of Huntington Disease: Insights from Magnetic Resonance Spectroscopy—A Systematic Review.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 21, p. 6390, doi. 10.3390/jcm13216390

By:

Martínez Lozada, Pablo S.;
Duque Perez, José;
Celi Salinas, Ronney;
Miranda Morales, Bryan;
Pazmiño Mesías, Juan Francisco;
García Ríos, Cecilia Alejandra;
Rodas, Jose A.;
Leon-Rojas, Jose E.

Publication type:

Article