Works about HISTONE deacetylase

Results: 3705

Management of T‐cell malignancies: Bench‐to‐bedside targeting of epigenetic biology.

Published in:

CA: A Cancer Journal for Clinicians, 2025, v. 75, n. 4, p. 282, doi. 10.3322/caac.70001

By:

Sabzevari, Ariana;
Ung, Johnson;
Craig, Jeffrey W.;
Jayappa, Kallesh D.;
Pal, Ipsita;
Feith, David J.;
Loughran, Thomas P.;
O'Connor, Owen A.

Publication type:

Article

白僵菌素产量对蝉花虫草侵染斜纹夜蛾的致病性影响.

Published in:

Mycosystema, 2025, v. 44, n. 6, p. 1, doi. 10.13346/j.mycosystema.240257

By:

俞孔见;
胡加付;
柴一秋;
蔡瑞杭

Publication type:

Article

Resveratrol: a potential alternative therapeutic agent for patients suffering from chronic obstructive pulmonary disease (COPD).

Published in:

Journal of Asian Natural Products Research, 2025, v. 27, n. 7, p. 951, doi. 10.1080/10286020.2025.2459597

By:

Ren, Ong Yan;
Siddiqui, Yasmeen;
Ansari, Mohammed Tahir;
Ali, Asgar

Publication type:

Article

Butyrate Selectively Targets Super‐Enhancers and Transcriptional Networks Associated with Human Mast Cell Function.

Published in:

European Journal of Immunology, 2025, v. 55, n. 6, p. 1, doi. 10.1002/eji.202451680

By:

Folkerts, Jelle;
de Bruijn, Marjolein J. W.;
van IJcken, Wilfred F. J.;
Hendriks, Rudi W.;
Stadhouders, Ralph

Publication type:

Article

Cyanobacterial Peptides in Anticancer Therapy: A Comprehensive Review of Mechanisms, Clinical Advances, and Biotechnological Innovation.

Published in:

Marine Drugs, 2025, v. 23, n. 6, p. 233, doi. 10.3390/md23060233

By:

Lee, Heayyean;
Nihan, Khuld;
Kwon, Yale Ryan

Publication type:

Article

Exploration of Bromodomain Proteins as Drug Targets for Niemann–Pick Type C Disease.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5769, doi. 10.3390/ijms26125769

By:

Parente, Martina;
Barthelemy, Amélie;
Tonini, Claudia;
Caputo, Sara;
Sacchi, Alessandra;
Leone, Stefano;
Segatto, Marco;
Pfrieger, Frank W.;
Pallottini, Valentina

Publication type:

Article

Discovery of Novel Imidazothiazole-Based Hydroxamic Acid Derivatives as Potent Indoleamine 2,3-Dioxygenase 1 and Histone Deacetylase 6 Dual Inhibitors.

Published in:

Molecules, 2025, v. 30, n. 12, p. 2508, doi. 10.3390/molecules30122508

By:

Zhang, Shi;
Wang, Yan-Fei;
Lu, Hai-Rui;
Yang, Xue-Qin;
Zhang, Ye;
Ma, Xian-Li;
Huang, Ri-Zhen

Publication type:

Article

Combined Phytochemical Sulforaphane and Dietary Fiber Inulin Contribute to the Prevention of ER-Negative Breast Cancer via PI3K/AKT/MTOR Pathway and Modulating Gut Microbial Composition.

Published in:

Nutrients, 2025, v. 17, n. 12, p. 2023, doi. 10.3390/nu17122023

By:

Wu, Huixin;
Witt, Brittany L.;
van der Pol, William J.;
Morrow, Casey D.;
Duck, Lennard W.;
Tollefsbol, Trygve O.

Publication type:

Article

Epigenetic Reprogramming of the Type III Interferon Response Potentiates Antiviral Activity and Suppresses Tumor Growth.

Published in:

PLoS Biology, 2014, v. 12, n. 1, p. 1, doi. 10.1371/journal.pbio.1001758

By:

Ding, Siyuan;
Khoury-Hanold, William;
Iwasaki, Akiko;
Robek, Michael D.

Publication type:

Article

An HDAC in the Cytoplasm, not the Nucleus, Plays a Pathogenic Role in Huntington's Disease.

Published in:

PLoS Biology, 2013, v. 11, n. 11, p. 1, doi. 10.1371/journal.pbio.1001718

By:

Robinson, Richard

Publication type:

Article

HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration.

Published in:

PLoS Biology, 2013, v. 11, n. 11, p. 1, doi. 10.1371/journal.pbio.1001717

By:

Mielcarek, Michal;
Landles, Christian;
Weiss, Andreas;
Bradaia, Amyaouch;
Seredenina, Tamara;
Inuabasi, Linda;
Osborne, Georgina F.;
Wadel, Kristian;
Touller, Chrystelle;
Butler, Rachel;
Robertson, Janette;
Franklin, Sophie A.;
Smith, Donna L.;
Park, Larry;
Marks, Paul A.;
Wanker, Erich E.;
Olson, Eric N.;
Luthi-Carter, Ruth;
van der Putten, Herman;
Beaumont, Vahri

Publication type:

Article

Deacetylation Ensures Timely Regulation of Flowering.

Published in:

PLoS Biology, 2013, v. 11, n. 9, p. 1, doi. 10.1371/journal.pbio.1001646

By:

Coombs, Amy

Publication type:

Article

Photoperiodic Regulation of Flowering Time through Periodic Histone Deacetylation of the Florigen Gene <i>FT</i>.

Published in:

PLoS Biology, 2013, v. 11, n. 9, p. 1, doi. 10.1371/journal.pbio.1001649

By:

Gu, Xiaofeng;
Wang, Yizhong;
He, Yuehui

Publication type:

Article

The ING1a Tumor Suppressor Regulates Endocytosis to Induce Cellular Senescence Via the Rb-E2F Pathway.

Published in:

PLoS Biology, 2013, v. 11, n. 3, p. 1, doi. 10.1371/journal.pbio.1001502

By:

Rajarajacholan, Uma Karthika;
Thalappilly, Subhash;
Riabowol, Karl

Publication type:

Article

Enzyme Inhibitor May Offer Dual Protection against Brain Disease.

Published in:

PLoS Biology, 2012, v. 10, n. 2, p. 1, doi. 10.1371/journal.pbio.1001270

By:

Choi, Charles Q.

Publication type:

Article

Histone Deacetylase Complexes Promote Trinucleotide Repeat Expansions.

Published in:

PLoS Biology, 2012, v. 10, n. 2, p. 1, doi. 10.1371/journal.pbio.1001257

By:

Debacker, Kim;
Frizzell, Aisling;
Gleeson, Olive;
Kirkham-McCarthy, Lucy;
Mertz, Tony;
Lahue, Robert S.

Publication type:

Article

Recruitment of Cln3 Cyclin to Promoters Controls Cell Cycle Entry via Histone Deacetylase and Other Targets.

Published in:

PLoS Biology, 2009, v. 7, n. 9, p. 1, doi. 10.1371/journal.pbio.1000189

By:

Hongyin Wang;
Carey, Lucas B.;
Ying Cai;
Wijnen, Herman;
Futcher, Bruce

Publication type:

Article

Dual Regulation by Pairs of Cyclin-Dependent Protein Kinases and Histone Deacetylases Controls G1 Transcription in Budding Yeast.

Published in:

PLoS Biology, 2009, v. 7, n. 9, p. 1, doi. 10.1371/journal.pbio.1000188

By:

Dongqing Huang;
Kaluarachchi, Supipi;
van Dyk, Dewald;
Friesen, Helena;
Sopko, Richelle;
Wei Ye;
Bastajian, Nazareth;
Moffat, Jason;
Sassi, Holly;
Costanzo, Michael;
Andrews, Brenda J.

Publication type:

Article

For Some Genes, Acetylation/Deacetylation Cycling Is the Real Turn-On.

Published in:

PLoS Biology, 2005, v. 3, n. 12, p. e431, doi. 10.1371/journal.pbio.0030431

By:

Robinson, Richard

Publication type:

Article

Singapore Anti-Cancer Drug Goes into Trial.

Published in:: Innovation, 2008, v. 8, n. 1, p. 6
Publication type:: Article

HDAC4, a prognostic and chromosomal instability marker, refines the predictive value of MGMT promoter methylation.

Published in:

Journal of Neuro-Oncology, 2015, v. 122, n. 2, p. 303, doi. 10.1007/s11060-014-1709-6

By:

Cheng, Wen;
Li, Mingyang;
Cai, Jinquan;
Wang, Kuanyu;
Zhang, Chuanbao;
Bao, Zhaoshi;
Liu, Yanwei;
Wu, Anhua

Publication type:

Article

P53-dependent antiproliferative and pro-apoptotic effects of trichostatin A (TSA) in glioblastoma cells.

Published in:

Journal of Neuro-Oncology, 2012, v. 107, n. 3, p. 503, doi. 10.1007/s11060-011-0791-2

By:

Bajbouj, K.;
Mawrin, C.;
Hartig, R.;
Schulze-Luehrmann, J.;
Wilisch-Neumann, A.;
Roessner, A.;
Schneider-Stock, R.

Publication type:

Article

Phase I study of panobinostat in combination with bevacizumab for recurrent high-grade glioma.

Published in:

Journal of Neuro-Oncology, 2012, v. 107, n. 1, p. 133, doi. 10.1007/s11060-011-0717-z

By:

Drappatz, J.;
Lee, E.;
Hammond, S.;
Grimm, S.;
Norden, A.;
Beroukhim, R.;
Gerard, M.;
Schiff, D.;
Chi, A.;
Batchelor, T.;
Doherty, L.;
Ciampa, A.;
LaFrankie, D.;
Ruland, S.;
Snodgrass, S.;
Raizer, J.;
Wen, P.

Publication type:

Article

Vorinostat modulates cell cycle regulatory proteins in glioma cells and human glioma slice cultures.

Published in:

Journal of Neuro-Oncology, 2011, v. 105, n. 2, p. 241, doi. 10.1007/s11060-011-0604-7

By:

Xu, Jihong;
Sampath, Deepa;
Lang, Frederick;
Prabhu, Sujit;
Rao, Ganesh;
Fuller, Gregory;
Liu, Yuanfang;
Puduvalli, Vinay

Publication type:

Article

Vorinostat enhances the cytotoxic effects of the topoisomerase I inhibitor SN38 in glioblastoma cell lines.

Published in:

Journal of Neuro-Oncology, 2010, v. 99, n. 2, p. 201, doi. 10.1007/s11060-010-0127-7

By:

Sarcar, Bhaswati;
Kahali, Soumen;
Chinnaiyan, Prakash

Publication type:

Article

Synergistic induction of NY-ESO-1 antigen expression by a novel histone deacetylase inhibitor, valproic acid, with 5-aza-2′-deoxycytidine in glioma cells.

Published in:

Journal of Neuro-Oncology, 2009, v. 92, n. 1, p. 15, doi. 10.1007/s11060-008-9732-0

By:

Sachie Oi;
Atsushi Natsume;
Motokazu Ito;
Yutaka Kondo;
Shinji Shimato;
Yuka Maeda;
Kiyoshi Saito;
Toshihiko Wakabayashi

Publication type:

Article

Histone acetylation resulting in resistance to methotrexate in choroid plexus cells.

Published in:

Journal of Neuro-Oncology, 2009, v. 91, n. 3, p. 279, doi. 10.1007/s11060-008-9709-z

By:

Preethi Prasad;
Hernan Vasquez;
Chandra Das;
Vidya Gopalakrishnan

Publication type:

Article

Valproic acid was well tolerated in heavily pretreated pediatric patients with high-grade glioma.

Published in:

Journal of Neuro-Oncology, 2008, v. 90, n. 3, p. 309

By:

Christof Kramm;
Rolf-Dieter Kortmann;
Torsten Pietsch;
Stefan Rutkowski;
Norbert Jorch;
Astrid Gnekow;
Pablo Driever

Publication type:

Article

Expression characterization and the promoter activity analysis of zebrafish hdac4.

Published in:

Fish Physiology & Biochemistry, 2012, v. 38, n. 2, p. 585, doi. 10.1007/s10695-011-9540-x

By:

Zhu, Kecheng;
Wang, Huanling;
Gul, Yasmeen;
Zhao, Yuhua;
Wang, Weimin;
Liu, Shasha;
Wang, Min

Publication type:

Article

Emerin and histone deacetylase 3 (HDAC3) cooperatively regulate expression and nuclear positions of MyoD, Myf5, and Pax7 genes during myogenesis.

Published in:

Chromosome Research, 2013, v. 21, n. 8, p. 765, doi. 10.1007/s10577-013-9381-9

By:

Demmerle, Justin;
Koch, Adam;
Holaska, James

Publication type:

Article

A key component Rxt3 in the Rpd3L histone deacetylase complex regulates development, stress tolerance, amylase production and kojic acid synthesis in Aspergillus oryzae.

Published in:

Biotechnology Letters, 2024, v. 46, n. 6, p. 1121, doi. 10.1007/s10529-024-03515-x

By:

Chang, Chaofeng;
Wang, Herui;
Liu, Yiling;
Xie, Yiting;
Xue, Dingxiang;
Zhang, Feng

Publication type:

Article

Identification and characterization of an acetyl esterase from Paenibacillus sp. XW-6-66 and its novel function in 7-aminocephalosporanic acid deacetylation.

Published in:

Biotechnology Letters, 2019, v. 41, n. 8/9, p. 1059, doi. 10.1007/s10529-019-02709-y

By:

Ding, Junmei;
Zhou, Yang;
Zhu, Hujie;
Deng, Ming;
Long, Liangchuan;
Yang, Yunjuan;
Wu, Qian;
Huang, Zunxi

Publication type:

Article

Copper oxide nanoparticles induce anticancer activity in A549 lung cancer cells by inhibition of histone deacetylase.

Published in:

Biotechnology Letters, 2018, v. 40, n. 2, p. 249, doi. 10.1007/s10529-017-2463-6

By:

Kalaiarasi, Arunachalam;
Sankar, Renu;
Anusha, Chidambaram;
Saravanan, Kandasamy;
Aarthy, Kalyanasundaram;
Karthic, Selvaraj;
Mathuram, Theodore lemuel;
Ravikumar, Vilwanathan

Publication type:

Article

Posttranslational modification and beyond: interplay between histone deacetylase 6 and heat-shock protein 90.

Published in:

Molecular Medicine, 2021, v. 27, n. 1, p. 1, doi. 10.1186/s10020-021-00375-3

By:

Liu, Ping;
Xiao, Ji;
Wang, Yiliang;
Song, Xiaowei;
Huang, Lianzhou;
Ren, Zhe;
Kitazato, Kaio;
Wang, Yifei

Publication type:

Article

Involvement of Hdac3-mediated inhibition of microRNA cluster 17-92 in bronchopulmonary dysplasia development.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. N.PAG, doi. 10.1186/s10020-020-00237-4

By:

Wang, Di;
Hong, Hui;
Li, Xiao-Xia;
Li, Jing;
Zhang, Zhi-Qun

Publication type:

Article

Synthesis, Biological Evaluation and in Silico Studies of Novel Urea/Thiourea Derivatives of Lenalidomide.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 12, p. 1, doi. 10.1002/jbt.70079

By:

Tok, Fatih;
Abas, Burçin İrem;
Başoğlu, Faika;
Çevik, Özge;
Karakuş, Sevgi;
Ece, Abdulilah

Publication type:

Article

C/EBPα alleviates hepatic ischemia‐reperfusion injury by inhibiting endoplasmic reticulum stress via HDAC1‐mediated deacetylation of ATF4.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 1, p. 1, doi. 10.1002/jbt.23630

By:

Li, Rong;
Yang, Longbao;
Li, Shunle;
Chen, Shuo;
Ren, Yifan;
Shen, Lin;
Dong, Lei;
Chen, Xi;
Li, Junhui;
Xu, Meng

Publication type:

Article

Design, synthesis, and histone deacetylase inhibition study of novel 4‐(2‐aminoethyl) phenol derivatives.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 1, p. 1, doi. 10.1002/jbt.23591

By:

Podili, Runesh;
Mishra, K. M. Abha;
Akkewar, Ashish S.;
Kumar, Sanjay;
Rayala, V. V. S. Prasanna Kumari;
Kulhari, Uttam;
Sahu, Bidya D.;
P., Radhakrishnanand;
Sethi, Kalyan K.

Publication type:

Article

Effects of dexmedetomidine on cognitive dysfunction and neuroinflammation via the HDAC2/HIF‐1α/PFKFB3 axis in a murine model of postoperative cognitive dysfunction.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 6, p. 1, doi. 10.1002/jbt.23044

By:

Liu, Yu‐Fang;
Hu, Rui;
Zhang, Long‐Fei;
Fan, Yong;
Xiao, Ji‐Feng;
Liao, Xing‐Zhi

Publication type:

Article

Vorinostat ameliorates IL‐1α‐induced reduction of type II collagen by inhibiting the expression of ELF3 in chondrocytes.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 9, p. 1, doi. 10.1002/jbt.22844

By:

Miao, Xudong;
Wu, Yongping;
Wang, Ping;
Zhang, Qiang;
Zhou, Chenhe;
Yu, Xinning;
Cao, Le

Publication type:

Article

Inhibition of histone deacetylases is the major pathway mediated by astaxanthin to antagonize LPS‐induced inflammatory responses in mammary epithelial cells.

Published in:

Journal of Biochemical & Molecular Toxicology, 2020, v. 34, n. 8, p. 1, doi. 10.1002/jbt.22507

By:

Venkidasamy, Baskar;
Thiruvengadam, Muthu;
Thirupathi, Prabhu;
Subramanian, Umadevi

Publication type:

Article

Brain region-specific regulation of histone acetylation and efflux transporters in mice.

Published in:

Journal of Biochemical & Molecular Toxicology, 2019, v. 33, n. 6, p. 1, doi. 10.1002/jbt.22318

By:

You, Dahea;
Hye Min Shin;
Mosaad, Fatimah;
Richardson, Jason R.;
Aleksunes, Lauren M.

Publication type:

Article

Recent advances in histone deacetylase targeted cancer therapy.

Published in:

Surgery Today, 2010, v. 40, n. 9, p. 809, doi. 10.1007/s00595-010-4300-6

By:

Hoshino, Isamu;
Matsubara, Hisahiro

Publication type:

Article

In vitro evaluation of the Aurora kinase inhibitor VX-680 for Hepatoblastoma.

Published in:

Pediatric Surgery International, 2012, v. 28, n. 6, p. 579, doi. 10.1007/s00383-012-3086-6

By:

Dewerth, Alexander;
Wonner, Timo;
Lieber, Justus;
Ellerkamp, Verena;
Warmann, Steven;
Fuchs, Jörg;
Armeanu-Ebinger, Sorin

Publication type:

Article

Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates.

Published in:

Nutrition Reviews, 2008, v. 66, p. S36, doi. 10.1111/j.1753-4887.2008.00065.x

By:

Dashwood, Roderick H.;
Ho, Emily

Publication type:

Article

Dietary polyphenols mediated regulation of oxidative stress and chromatin remodeling in inflammation.

Published in:

Nutrition Reviews, 2008, v. 66, p. S42, doi. 10.1111/j.1753-4887.2008.00067.x

By:

Rahman, Irfan

Publication type:

Article

Drosophila SAP18, a member of the Sin3/Rpd3 histone deacetylase complex, interacts with Bicoid and inhibits its activity.

Published in:

Development Genes & Evolution, 2001, v. 211, n. 3, p. 109, doi. 10.1007/s004270100135

By:

Wencheng Zhu;
Foehr, Marisa;
Jaynes, James B.;
Hanes, Steven D.

Publication type:

Article

New connections between ubiquitylation and methylation in the co-transcriptional histone modification network.

Published in:

Current Genetics, 2021, v. 67, n. 5, p. 695, doi. 10.1007/s00294-021-01196-x

By:

Pinto, Daniel;
Pagé, Vivane;
Fisher, Robert P.;
Tanny, Jason C.

Publication type:

Article

Forkhead transcription factor Fkh1: insights into functional regulatory domains crucial for recruitment of Sin3 histone deacetylase complex.

Published in:

Current Genetics, 2021, v. 67, n. 3, p. 487, doi. 10.1007/s00294-021-01158-3

By:

Aref, Rasha;
Sanad, Marwa N. M. E.;
Schüller, Hans-Joachim

Publication type:

Article

How do cells count multi-copy genes?: "Musical Chair" model for preserving the number of rDNA copies.

Published in:

Current Genetics, 2019, v. 65, n. 4, p. 883, doi. 10.1007/s00294-019-00956-0

By:

Iida, Tetsushi;
Kobayashi, Takehiko

Publication type:

Article