Works about GUANYLATE cyclase

Results: 1313

Cardiac Damage in Hypertension: From Molecular Mechanisms to Novel Therapeutic Approaches.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5610, doi. 10.3390/ijms26125610

By:

Gallo, Giovanna;
Rubattu, Speranza

Publication type:

Article

A Distributed Chemosensory Circuit for Oxygen Preference in C. elegans.

Published in:

PLoS Biology, 2006, v. 4, n. 9, p. 1588, doi. 10.1371/journal.pbio.0040274

By:

Chang, Andy J.;
Chronis, Nikolas;
Karow, David S.;
Marletta, Michael A.;
Bargmann, Cornelia I.

Publication type:

Article

The soluble guanylyl cyclase activator BAY 60-2770 potently relaxes the pulmonary artery on congenital diaphragmatic hernia rabbit model.

Published in:

Pediatric Surgery International, 2014, v. 30, n. 10, p. 1031, doi. 10.1007/s00383-014-3561-3

By:

Rojas-Moscoso, Julio;
Antunes, Edson;
Figueira, Rebeca;
Gonçalves, Frances;
Simões, Ana;
Sbragia, Lourenço

Publication type:

Article

The role of octopamine and crustacean hyperglycemic hormone (CHH) in branchial acid–base regulation in the European green crab, Carcinus maenas.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2023, v. 193, n. 5, p. 509, doi. 10.1007/s00360-023-01507-3

By:

Fehsenfeld, Sandra;
Quijada-Rodriguez, Alex R.;
Calosi, Piero;
Weihrauch, Dirk

Publication type:

Article

Identification and expression of natriuretic peptide receptor type-A and -B mRNA in freshwater and seawater rainbow trout.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2007, v. 177, n. 2, p. 259, doi. 10.1007/s00360-006-0127-2

By:

Nankervis, Scott;
Powell, Mark;
McLeod, Janet;
Toop, Tes

Publication type:

Article

A cis-regulatory element essential for photoreceptor cell-specific expression of a medaka retinal guanylyl cyclase gene.

Published in:

Development Genes & Evolution, 2001, v. 211, n. 3, p. 145, doi. 10.1007/s004270100136

By:

Kusakabe, Takehiro;
Suzuki, Norio

Publication type:

Article

Correlation of nitric oxide produced by an inducible nitric oxide synthase-like protein with enhanced expression of the phenylpropanoid pathway in Inonotus obliquus cocultured with Phellinus morii.

Published in:

Applied Microbiology & Biotechnology, 2015, v. 99, n. 10, p. 4361, doi. 10.1007/s00253-014-6367-2

By:

Zhao, Yanxia;
Xi, Qi;
Xu, Qian;
He, Meihong;
Ding, Jianing;
Dai, Yucheng;
Keller, Nancy;
Zheng, Weifa

Publication type:

Article

Clinical Significance of Guanylate Cyclase Stimulator, Riociguat, on Right Ventricular Functional Improvement in Patients with Pulmonary Hypertension.

Published in:

Cardiology, 2021, v. 146, n. 1, p. 130, doi. 10.1159/000510860

By:

Murata, Mitsushige;
Kawakami, Takashi;
Kataoka, Masaharu;
Moriyama, Hidenori;
Hiraide, Takahiro;
Kimura, Mai;
Endo, Jin;
Kohno, Takashi;
Itabashi, Yuji;
Fukuda, Keiichi

Publication type:

Article

Bayer: Phase 2 Trial of Investigational Soluble Guanylate Cyclase Activator for Chronic Kidney Disease Begins.

Published in:

Patient Care (Online), 2024, p. 1

By:

Jennings, Sydney

Publication type:

Article

Safety and efficacy of linaclotide in children aged 2–5 years with functional constipation: Phase 2, randomized study.

Published in:

Journal of Pediatric Gastroenterology & Nutrition, 2024, v. 79, n. 3, p. 510, doi. 10.1002/jpn3.12306

By:

Di Lorenzo, Carlo;
Robert, Jon;
Rodriguez‐Araujo, Gerardo;
Shakhnovich, Valentina;
Xie, Wangang;
Nurko, Samuel;
Saps, Miguel

Publication type:

Article

Proteomic surveys of the mouse heart unveil cardiovascular responses to nitric oxide/cGMP signaling deficiencies.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08203-8

By:

Mohanty, Ipsita;
Fazelinia, Hossein;
Raimo, Serena;
Ding, Hua;
Spruce, Lynn;
Symeonidou, Maria;
Tenopoulou, Margarita;
Ichinose, Fumito;
Yamashita, Hirotaka;
Shimokawa, Hiroaki;
Masato, Tsutsui;
Doulias, Paschalis-Thomas;
Ischiropoulos, Harry

Publication type:

Article

New Therapeutics for Heart Failure Worsening: Focus on Vericiguat.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 14, p. 4209, doi. 10.3390/jcm13144209

By:

Russo, Patrizia;
Vitiello, Laura;
Milani, Francesca;
Volterrani, Maurizio;
Rosano, Giuseppe M. C.;
Tomino, Carlo;
Bonassi, Stefano

Publication type:

Article

Platelet Cyclic GMP Levels Are Reduced in Patients with Primary Aldosteronism.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 22, p. 7081, doi. 10.3390/jcm12227081

By:

Sala, Carla;
Rescaldani, Marta;
Gherbesi, Elisa;
Bolla, Gianni;
Cuspidi, Cesare;
Ruscica, Massimiliano;
Carugo, Stefano

Publication type:

Article

Initial Experience of Vericiguat Treatment in Patients with Heart Failure and Reduced Ejection Fraction.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 13, p. 4396, doi. 10.3390/jcm12134396

By:

Nakamura, Makiko;
Imamura, Teruhiko;
Kinugawa, Koichiro

Publication type:

Article

Influence of Guanine-Based Purines on the Oxidoreductive Reactions Involved in Normal or Altered Brain Functions.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 3, p. 1172, doi. 10.3390/jcm12031172

By:

Zuccarini, Mariachiara;
Pruccoli, Letizia;
Balducci, Martina;
Giuliani, Patricia;
Caciagli, Francesco;
Ciccarelli, Renata;
Di Iorio, Patrizia

Publication type:

Article

Contemporary Pillars of Heart Failure with Reduced Ejection Fraction Medical Therapy.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 19, p. 4409, doi. 10.3390/jcm10194409

By:

Rahamim, Eldad;
Nachman, Dean;
Yagel, Oren;
Yarkoni, Merav;
Elbaz-Greener, Gabby;
Amir, Offer;
Asleh, Rabea

Publication type:

Article

Looking for a Tailored Therapy for Heart Failure: Are We Capable of Treating the Patient Instead of the Disease?

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 19, p. 4325, doi. 10.3390/jcm10194325

By:

Fucili, Alessandro;
Cimaglia, Paolo;
Severi, Paolo;
Giannini, Francesco;
Boccadoro, Alberto;
Micillo, Marco;
Rapezzi, Claudio;
Tavazzi, Luigi;
Ferrari, Roberto

Publication type:

Article

5-HT4 receptor-mediated vasorelaxation occurs through a cyclic mononucleotide-dependent mechanism in the isolated bovine lateral saphenous vein.

Published in:

Journal of Animal Science, 2024, v. 102, p. 268, doi. 10.1093/jas/skae234.309

By:

Trotta, Ronald J.;
Harmon, David L.;
Klotz, James L.

Publication type:

Article

A major gene for host response to porcine reproductive and respiratory syndrome is not unfavorably associated with overall performance under nonchallenging conditions in commercial pig lines.

Published in:

Journal of Animal Science, 2017, v. 95, n. 7, p. 2838, doi. 10.2527/jas.2017.1524

By:

Dunkelberger, J. R.;
Dekkers, J. C. M.;
Mathur, P. K.;
Knol, E. F.;
Lopes, M. S.

Publication type:

Article

Signaling Paradigms of H 2 S-Induced Vasodilation: A Comprehensive Review.

Published in:

Antioxidants, 2024, v. 13, n. 10, p. 1158, doi. 10.3390/antiox13101158

By:

Munteanu, Constantin;
Popescu, Cristina;
Vlădulescu-Trandafir, Andreea-Iulia;
Onose, Gelu

Publication type:

Article

Inhibitory Peptide of Soluble Guanylyl Cyclase/Trx1 Interface Blunts the Dual Redox Signaling Functions of the Complex.

Published in:

Antioxidants, 2023, v. 12, n. 4, p. 906, doi. 10.3390/antiox12040906

By:

Cui, Chuanlong;
Shu, Ping;
Sadeghian, Tanaz;
Younis, Waqas;
Li, Hong;
Beuve, Annie

Publication type:

Article

Optogenetic manipulation of neuronal and cardiomyocyte functions in zebrafish using microbial rhodopsins and adenylyl cyclases.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.83975

By:

Hanako Hagio;
Wataru Koyama;
Shiori Hosaka;
Song, Aysenur Deniz;
Janchiv Narantsatsral;
Koji Matsuda;
Takashi Shimizu;
Shoko Hososhima;
Tsunoda, Satoshi P.;
Hideki Kandori;
Masahiko Hibi

Publication type:

Article

Structural insight into guanylyl cyclase receptor hijacking of the kinase-Hsp90 regulatory mechanism.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.86784

By:

Caveney, Nathanael A.;
Naotaka Tsutsumi;
Garcia, K. Christopher

Publication type:

Article

Npr3 regulates neural crest and cranial placode progenitors formation through its dual function as clearance and signaling receptor.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.84036

By:

Devotta, Arun;
Juraver-Geslin, Hugo;
Griffin, Casey;
Saint-Jeannet, Jean-Pierre

Publication type:

Article

A Randomized, Placebo‐Controlled, Multiple‐Ascending‐Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Soluble Guanylate Cyclase Stimulator Praliciguat in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2019, v. 8, n. 5, p. 564, doi. 10.1002/cpdd.627

By:

Hanrahan, John P.;
Wakefield, James D.;
Wilson, Phebe J.;
Mihova, Marina;
Chickering, Jennifer G.;
Ruff, Dennis;
Hall, Michael;
Milne, G. Todd;
Currie, Mark G.;
Profy, Albert T.

Publication type:

Article

Analysis of research trends and development prospects of soluble guanylate cyclase stimulators/activators: using bibliometric methods.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1501330

By:

Yan, Bing Ju;
Zhang, Jing;
Wang, Jun;
Yuan, Hong Xia

Publication type:

Article

Comparison of sGC activator and sGC stimulator in 5/6 nephrectomized rats on high-salt-diet.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1480186

By:

Xin Chen;
Yingquan Xiong;
Shufei Zeng;
Delić, Denis;
Gaballa, Mohamed;
Kalk, Philipp;
Klein, Thomas;
Krämer, Bernhard K.;
Hocher, Berthold

Publication type:

Article

The Guanylate Cyclase C—cGMP Signaling Axis Opposes Intestinal Epithelial Injury and Neoplasia.

Published in:

Frontiers in Oncology, 2018, p. N.PAG, doi. 10.3389/fonc.2018.00299

By:

Rappaport, Jeffrey A.;
Waldman, Scott A.

Publication type:

Article

Safety, tolerability, pharmacodynamics and pharmacokinetics of the soluble guanylyl cyclase activator BI 685509 in patients with diabetic kidney disease: A randomized trial.

Published in:

Diabetes, Obesity & Metabolism, 2023, v. 25, n. 8, p. 2218, doi. 10.1111/dom.15099

By:

Cherney, David Z. I.;
de Zeeuw, Dick;
Heerspink, Hiddo J. L.;
Cardona, Jose;
Desch, Marc;
Wenz, Arne;
Schulze, Friedrich;
Nangaku, Masaomi

Publication type:

Article

Dapagliflozin reduces systolic blood pressure and modulates vasoactive factors.

Published in:

Diabetes, Obesity & Metabolism, 2021, v. 23, n. 7, p. 1614, doi. 10.1111/dom.14377

By:

Ghanim, Husam;
Batra, Manav;
Green, Kelly;
Hejna, Jeanne;
Abuaysheh, Sanaa;
Makdissi, Antione;
Chaudhuri, Ajay;
Dandona, Paresh

Publication type:

Article

Hydrogen Peroxide-Dependent Arteriolar Dilation in Contracting Muscle of Rats Fed Normal and High Salt Diets.

Published in:

Microcirculation, 2007, v. 14, n. 8, p. 779, doi. 10.1080/10739680701444057

By:

Marvar, Paul J.;
Hammer, Leah W.;
Boegehold, Matthew A.

Publication type:

Article

Distinct molecular requirements for activation or stabilization of soluble guanylyl cyclase upon haem oxidation-induced degradation.

Published in:

2009

By:

Hoffmann, L. S.;
Schmidt, P. M.;
Keim, Y.;
Schaefer, S.;
Schmidt, H. H. H. W.;
Stasch, J. P.

Publication type:

journal article

Desensitization of the soluble guanylyl cyclase/cGMP pathway by lipopolysaccharide in rat isolated pulmonary artery but not aorta.

Published in:

British Journal of Pharmacology, 2008, v. 155, n. 8, p. 1164, doi. 10.1038/bjp.2008.358

By:

El-Awady, M. S. H.;
Smirnov, S. V.;
Watson, M. L.

Publication type:

Article

cGMP-independent anti-tumour actions of the inhibitor of soluble guanylyl cyclase, ODQ, in prostate cancer cell lines.

Published in:

2008

By:

Haramis, G.;
Zhou, Z.;
Pyriochou, A.;
Koutsilieris, M.;
Roussos, C.;
Papapetropoulos, A.

Publication type:

journal article

Effect of oral organic nitrates on expression and activity of vascular soluble guanylyl cyclase.

Published in:

2008

By:

Oppermann, M.;
Dao, V. T.-V.;
Suvorava, T.;
Bas, M.;
Kojda, G.

Publication type:

journal article

Kaempferol stimulates large conductance Ca2+ -activated K+ (BKCa) channels in human umbilical vein endothelial cells via a cAMP/PKA-dependent pathway.

Published in:

2008

By:

Xu, Y. C.;
Leung, G. P. H.;
Wong, P. Y. D.;
Vanhoutte, P. M.;
Man, R. Y. K.

Publication type:

journal article

Probing the presence of the ligand-binding haem in cellular nitric oxide receptors.

Published in:

2008

By:

Roy, B.;
Mo, E.;
Vernon, J.;
Garthwaite, J.

Publication type:

journal article

Protein kinase G regulates the basal tension and plays a major role in nitrovasodilator-induced relaxation of porcine coronary veins.

Published in:

2007

By:

Qi, H.;
Zheng, X.;
Qin, X.;
Dou, D.;
Xu, H.;
Raj, J. U.;
Gao, Y.

Publication type:

journal article

Cyclic GMP and protein kinase-G in myocardial ischaemia-reperfusion: opportunities and obstacles for survival signaling.

Published in:

2007

By:

Burley, D. S.;
Ferdinandy, P.;
Baxter, G. F.

Publication type:

journal article

Modulation of vascular function by perivascular adipose tissue: the role of endothelium and hydrogen peroxide.

Published in:

British Journal of Pharmacology, 2007, v. 151, n. 3, p. 323, doi. 10.1038/sj.bjp.0707228

By:

Gao, Y.-J.;
Lu, C.;
Su, L.-Y.;
Sharma, A. M.;
Lee, R. M. K. W.

Publication type:

Article

Regulation of the expression of soluble guanylyl cyclase by reactive oxygen species.

Published in:

2007

By:

Gerassimou, C;
Kotanidou, A;
Zhou, Z;
Simoes, D D C;
Roussos, C;
Papapetropoulos, A;
Simoes, D C M

Publication type:

journal article

Regulation of the expression of soluble guanylyl cyclase by reactive oxygen species.

Published in:

2007

By:

Gerassimou, C;
Kotanidou, A;
Zhou, Z;
Simoes, D C M;
Roussos, C;
Papapetropoulos, A

Publication type:

Correction Notice

Inhibitors of phosphodiesterase 5 (PDE 5) inhibit the nerve-induced release of nitric oxide from the rabbit corpus cavernosum.

Published in:

British Journal of Pharmacology, 2007, v. 150, n. 3, p. 353, doi. 10.1038/sj.bjp.0706991

By:

Hallén, K.;
Wiklund, N. P.;
Gustafsson, L. E.

Publication type:

Article

Study on the cyclic GMP-dependency of relaxations to endogenous and exogenous nitric oxide in the mouse gastrointestinal tract.

Published in:

British Journal of Pharmacology, 2007, v. 150, n. 1, p. 88, doi. 10.1038/sj.bjp.0706964

By:

De Man, J. G.;
De Winter, B. Y.;
Herman, A. G.;
Pelckmans, P. A.

Publication type:

Article

Reciprocal regulation of human soluble and particulate guanylate cyclases in vivo.

Published in:

British Journal of Pharmacology, 2006, v. 149, n. 6, p. 797, doi. 10.1038/sj.bjp.0706920

By:

Madhani, M.;
Okorie, M.;
Hobbs, A. J.;
MacAllister, R. J.

Publication type:

Article

Heme oxygenase/carbon monoxide-biliverdin pathway down regulates neutrophil rolling, adhesion and migration in acute inflammation.

Published in:

2006

By:

Freitas, A.;
Alves-Filho, J. C.;
Secco, D. D.;
Neto, A. F.;
Ferreira, S. H.;
Barja-Fidalgo, C.;
Cunha, F. Q.

Publication type:

journal article

NO-independent activation of soluble guanylate cyclase prevents disease progression in rats with 5/6 nephrectomy.

Published in:

British Journal of Pharmacology, 2006, v. 148, n. 6, p. 853, doi. 10.1038/sj.bjp.0706792

By:

Kalk, Philipp;
Godes, Michael;
Relle, Katharina;
Rothkegel, Christiane;
Hucke, Andreas;
Stasch, Johannes-Peter;
Hocher, Berthold

Publication type:

Article

KMUP-1, a xanthine derivative, induces relaxation of guinea-pig isolated trachea: the role of the epithelium, cyclic nucleotides and K<sup>+</sup> channels.

Published in:

British Journal of Pharmacology, 2004, v. 142, n. 7, p. 1105, doi. 10.1038/sj.bjp.0705791

By:

Wu, Bin-Nan;
Lin, Rong-Jyh;
Yi-Ching Lo;
Kuo-Pyng Shen;
Chao-Chuan Wang;
Young-Tso Lin;
Ing-Jun Chen

Publication type:

Article

Membrane-association and the sensitivity of guanylyl cyclase-coupled receptors to nitric oxide.

Published in:

British Journal of Pharmacology, 2004, v. 141, n. 7, p. 1087, doi. 10.1038/sj.bjp.0705745

By:

Wykes, Victoria;
Garthwaite, John

Publication type:

Article

Catalytic Receptors.

Published in:: British Journal of Pharmacology, 2004, v. 141, p. S93, doi. 10.1038/sj.bjp.0705676
Publication type:: Article