Works about GENETIC risk score

Results: 871

Following the Action of Atypical Antipsychotic Clozapine and Possible Prediction of Treatment Response in Schizophrenia.

Published in:

Life (2075-1729), 2025, v. 15, n. 6, p. 830, doi. 10.3390/life15060830

By:

Năstase, Mihai-Gabriel;
Vasile, Antonia Ioana;
Pietreanu, Arina Cipriana;
Trifu, Simona

Publication type:

Article

Psychotropic‐induced lipid disturbances.

Published in:

Brown University Psychopharmacology Update, 2025, v. 36, n. 4, p. 2, doi. 10.1002/pu.31286

By:

Lam, Y. W. Francis

Publication type:

Article

Refining clinical decision strategies and prostate cancer detection through fine adjustments in the combination of PSA-derived parameters and MRI.

Published in:

2024

By:

Muglia, Valdair Francisco

Publication type:

Editorial

Significance of Gene Polymorphism and Gene Expression of BACE2 in Swedish Patients with Colorectal Cancer.

Published in:

Oncology, 2025, v. 103, n. 1, p. 48, doi. 10.1159/000540887

By:

Dimberg, Jan;
Shamoun, Levar;
af Geijerstam, Kristin;
Landerholm, Kalle;
Wågsäter, Dick

Publication type:

Article

Immune-aging at diagnosis determines T-cell recovery in childhood leukemia survivors.

Published in:

NPJ Aging, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41514-025-00233-0

By:

Dhodapkar, Kavita M.;
Castellino, Sharon;
Kapadia, Shivani;
Azeem, Maryam I.;
Horvat, Ava;
Lawrence, Taylor;
DeRyckere, Deborah;
Dhodapkar, Madhav V.

Publication type:

Article

Multi-modal machine learning approach for early detection of neurodegenerative diseases leveraging brain MRI and wearable sensor data.

Published in:

PLoS Digital Health, 2025, v. 4, n. 4, p. 1, doi. 10.1371/journal.pdig.0000795

By:

Li, Andrew;
Lian, Jie;
Vardhanabhuti, Varut

Publication type:

Article

Using machine learning and single nucleotide polymorphisms for improving rheumatoid arthritis risk Prediction in postmenopausal women.

Published in:

PLoS Digital Health, 2025, v. 4, n. 4, p. 1, doi. 10.1371/journal.pdig.0000790

By:

Xu, Yingke;
Wu, Qing

Publication type:

Article

Exploring the causal relationship between CX3CL1 and prostate cancer prognosis using Mendelian randomization.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03001-4

By:

Li, Weisheng;
Xia, Baoguo;
Chu, Weixin;
Lu, Likui;
Liu, Xuedong

Publication type:

Article

The influence of RAD51 (rs1801320) on breast cancer risk: an updated meta-analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02012-5

By:

Khan, Najeeb Ullah;
Alqarni, Sana S.;
Yousuf, Amjad;
Shehzad, Iqra;
Khan, Waqas;
Gu, Wei;
Chen, Tianhui

Publication type:

Article

Association between leukocyte telomere length and renal cell carcinoma: insight from Mendelian randomization study.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02027-y

By:

Chen, Xiao-bin;
Wang, Li;
Zhu, Ping-yu

Publication type:

Article

Development and validation of disulfidptosis-related genes signature for patients with glioma.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01664-z

By:

Wang, Jia;
Luo, Junchi;
Yang, Sha;
Deng, Yongbing;
Chen, Peng;
Tan, Ying;
Liu, Yang

Publication type:

Article

Association of fine particulate matter constituents with chronic obstructive pulmonary disease and the effect modification of genetic susceptibility.

Published in:

NPJ Climate & Atmospheric Science, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s41612-025-00967-4

By:

Xing, Meiqi;
Cui, Feipeng;
Zheng, Lei;
Ma, Yudiyang;
Wang, Jianing;
Tang, Linxi;
Chen, Ning;
Zhao, Xinru;
Tian, Yaohua;
Su, Binbin

Publication type:

Article

Is Gauchian genotyping of GBA1 variants reliable?

Published in:

Communications Biology, 2025, p. 1, doi. 10.1038/s42003-025-08059-y

By:

Tayebi, Nahid;
Lichtenberg, Jens;
Hertz, Ellen;
Sidransky, Ellen

Publication type:

Article

Is Gauchian genotyping of GBA1 variants reliable?

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08059-y

By:

Tayebi, Nahid;
Lichtenberg, Jens;
Hertz, Ellen;
Sidransky, Ellen

Publication type:

Article

Assessment of polygenic risk score performance in East Asian populations for ten common diseases.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07767-9

By:

Jung, Hae-Un;
Jung, Hyein;
Baek, Eun Ju;
Kang, Ji-One;
Kwon, Shin Young;
You, Jaeyoon;
Lim, Ji Eun;
Oh, Bermseok

Publication type:

Article

Assessment of polygenic risk score performance in East Asian populations for ten common diseases.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07767-9

By:

Jung, Hae-Un;
Jung, Hyein;
Baek, Eun Ju;
Kang, Ji-One;
Kwon, Shin Young;
You, Jaeyoon;
Lim, Ji Eun;
Oh, Bermseok

Publication type:

Article

Cross-species analysis of genetic architecture and polygenic risk scores for non-contact ACL rupture in dogs and humans.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-024-07395-9

By:

Momen, Mehdi;
Kearney, Hannah K.;
Patterson, Margaret M.;
Sample, Susannah J.;
Zhao, Zijie;
Lu, Qiongshi;
Rosa, Guilherme J. M.;
Muir, Peter

Publication type:

Article

Polygenic risk and rare variant gene clustering enhance cancer risk stratification for breast and prostate cancers.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06995-9

By:

Kang, Joon Ho;
Lee, Youngkee;
Kim, Dong Jun;
Kim, Ji-Woong;
Cheon, Myeong Jae;
Lee, Byung-Chul

Publication type:

Article

Polygenic Risk Score Is Associated with Developing and Dying from Lung Cancer in the National Lung Screening Trial.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 9, p. 3110, doi. 10.3390/jcm14093110

By:

Young, Robert P.;
Scott, Raewyn J;
Callender, Tom;
Duan, Fenghai;
Billings, Paul;
Aberle, Denise R.;
Gamble, Greg D.

Publication type:

Article

A Novel Screening Approach for Familial Hypercholesterolemia: A Genetic Study on Patients Detected Using Preexisting Centralized Analytics.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 8, p. 2780, doi. 10.3390/jcm14082780

By:

Sánchez-Prieto, Joaquín;
Sabatel, Fernando;
Moreno, Fátima;
Arias, Miguel A.;
Rodríguez-Padial, Luis

Publication type:

Article

A Genetic Risk Score for Recurrent Miscarriages Based on Polymorphisms in Platelet Glycoproteins and Adhesion Molecules Genes.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 7, p. 2355, doi. 10.3390/jcm14072355

By:

Vlachadis, Nikolaos;
Christodoulaki, Chryssi;
Tsamadias, Vassilios;
Peitsidis, Panagiotis;
Machairiotis, Nikolaos;
Sioutis, Dimos;
Vlahos, Nikolaos F.;
Economou, Emmanuel;
Panagopoulos, Periklis

Publication type:

Article

Migraine Genetic Susceptibility Does Not Strongly Influence Migraine Characteristics and Outcomes in a Treated, Real-World, Community Cohort.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 2, p. 536, doi. 10.3390/jcm14020536

By:

Chase, Bruce A.;
Frigerio, Roberta;
Rubin, Susan;
Semenov, Irene;
Meyers, Steven;
Mark, Angela;
Freedom, Thomas;
Marcus, Revital;
Dafer, Rima;
Wei, Jun;
Zheng, Siqun L.;
Xu, Jianfeng;
Mulford, Ashley J.;
Sanders, Alan R.;
Pham, Anna;
Epshteyn, Alexander;
Maraganore, Demetrius;
Markopoulou, Katerina

Publication type:

Article

An Integrative Migraine Polygenic Risk Score Is Associated with Age at Onset But Not Chronification.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 21, p. 6483, doi. 10.3390/jcm13216483

By:

Chase, Bruce A.;
Frigerio, Roberta;
Rubin, Susan;
Franada, Tiffani;
Semenov, Irene;
Meyers, Steven;
Bergman-Bock, Stuart;
Mark, Angela;
Freedom, Thomas;
Marcus, Revital;
Dafer, Rima;
Wei, Jun;
Zheng, Siqun L.;
Xu, Jianfeng;
Mulford, Ashley J.;
Sanders, Alan R.;
Pham, Anna;
Epshteyn, Alexander;
Maraganore, Demetrius;
Markopoulou, Katerina

Publication type:

Article

Biomarker-Based Precision Therapy for Alzheimer's Disease: Multidimensional Evidence Leading a New Breakthrough in Personalized Medicine.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 16, p. 4661, doi. 10.3390/jcm13164661

By:

Bougea, Anastasia;
Gourzis, Philippos

Publication type:

Article

Genetic Susceptibility to Arrhythmia Phenotypes in a Middle Eastern Cohort of 14,259 Whole-Genome Sequenced Individuals.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 4, p. 1102, doi. 10.3390/jcm13041102

By:

Qafoud, Fatima;
Elshrif, Mohamed;
Kunji, Khalid;
Althani, Asma;
Salam, Amar;
Al Suwaidi, Jassim;
Asaad, Nidal;
Darbar, Dawood;
Saad, Mohamad

Publication type:

Article

Exploring the impact of genetic factors and fatty acid quality on visceral and overall Fat levels in overweight and obese women: a genetic risk score study.

Published in:

BMC Nutrition, 2025, v. 11, n. 1, p. 1, doi. 10.1186/s40795-024-00953-8

By:

Rasaei, Niloufar;
Tavakoli, Atefeh;
Mohammadpour, Saba;
Karimi, Mehdi;
Khadem, Alireza;
Mohamadi, Azam;
Fatemi, Seyedeh Fatemeh;
Gholami, Fatemeh;
Mirzaei, Khadijeh

Publication type:

Article

Effects of the Interaction Between Oxidative Balance Score and Polygenic Risk Scores on Incidence of Metabolic Syndrome in Middle-Aged Korean Adults.

Published in:

Antioxidants, 2024, v. 13, n. 12, p. 1556, doi. 10.3390/antiox13121556

By:

Kim, Minyeong;
Shin, Dayeon

Publication type:

Article

Genetic Predisposition of Atherosclerotic Cardiovascular Disease in Ancient Human Remains.

Published in:

Annals of Global Health, 2024, v. 90, n. 1, p. 1, doi. 10.5334/aogh.4366

By:

Wurst, Christina;
Maixner, Frank;
Paladin, Alice;
Mussauer, Alexandra;
Valverde, Guido;
Narula, Jagat;
Thompson, Randall;
Zink, Albert

Publication type:

Article

Association of alcohol consumption with aortic aneurysm and dissection risk: results from the UK Biobank cohort study.

Published in:

World Journal of Emergency Medicine, 2024, v. 15, n. 6, p. 465, doi. 10.5847/wjem.j.1920-8642.2024.096

By:

Yaowen Liang;
Guoxiang Zou;
Dingchen Wang;
Weiyue Zeng;
Jiarui Zhang;
Xiaoran Huang;
Miao Lin;
Cong Mai;
Fei'er Song;
Yuelin Zhang;
Jinxiu Meng;
Hongliang Feng;
Yu Huang;
Xin Li

Publication type:

Article

Association between loneliness and incident atrial fibrillation across different genetic predisposition: findings from the UK Biobank.

Published in:

European Journal of Medical Research, 2024, v. 29, n. 1, p. 1, doi. 10.1186/s40001-024-02105-x

By:

Liu, Zechen;
Song, Yanjun;
Shi, Shanshan;
Zheng, Zhihao;
Song, Weihua;
Zhang, Wenjia;
Dou, Kefei

Publication type:

Article

Association of IRX6 rs6499755 and HAAO rs3816183 Polymorphisms With Hypospadias Susceptibility in Northern Chinese Han Population.

Published in:

Genetics Research, 2025, v. 2025, p. 1, doi. 10.1155/genr/5775560

By:

Liu, Nan;
Yu, Yuping;
Chen, Ziying;
Shu, Jianbo;
Chen, Xiaofang;
Xu, Guodong;
Cai, Chunquan;
Ahmad, Irfan

Publication type:

Article

Associations of combined phenotypic aging and genetic risk with incident cancer: A prospective cohort study.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.91101

By:

Lijun Bian;
Zhimin Ma;
Xiangjin Fu;
Chen Ji;
Tianpei Wang;
Caiwang Yan;
Juncheng Dai;
Hongxia Ma;
Zhibin Hu;
Hongbing Shen;
Lu Wang;
Meng Zhu;
Guangfu Jin

Publication type:

Article

Deciphering the complex relationship between type 2 diabetes and fracture risk with both genetic and observational evidence.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.89281

By:

Pianpian Zhao;
Zhifeng Sheng;
Lin Xu;
Peng Li;
Wenjin Xiao;
Chengda Yuan;
Zhanwei Xu;
Mengyuan Yang;
Yu Qian;
Jiadong Zhong;
Jiaxuan Gu;
Karasik, David;
Hou-Feng Zheng

Publication type:

Article

Identifying metabolic features of colorectal cancer liability using Mendelian randomization.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.87894

By:

Bull, Caroline;
Hazelwood, Emma;
Bell, Joshua A.;
Tan, Vanessa;
Constantinescu, Andrei-Emil;
Borges, Carolina;
Legge, Danny;
Burrows, Kimberley;
Huyghe, Jeroen R.;
Brenner, Hermann;
Castellvi-Bel, Sergi;
Chan, Andrew T.;
Sun-Seog Kweon;
Le Marchand, Loic;
Li Li;
Cheng, Iona;
Pai, Rish K.;
Figueiredo, Jane C.;
Murphy, Neil;
Gunter, Marc J.

Publication type:

Article

From Data to Harm: Exploring Ethical and Social Implications of Polygenic Scores for Social Traits.

Published in:

American Journal of Bioethics, 2025, v. 25, n. 2, p. 82, doi. 10.1080/15265161.2024.2441743

By:

Cadigan, R. Jean;
Watson, Sara;
Prince, Anya E. R.

Publication type:

Article

Optimization of multi-ancestry polygenic risk score disease prediction models.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-02903-1

By:

Lerga-Jaso, Jon;
Terpolovsky, Andrew;
Novković, Biljana;
Osama, Alex;
Manson, Charlie;
Bohn, Sandra;
De Marino, Adriano;
Kunitomi, Mark;
Yazdi, Puya G.

Publication type:

Article

Metabolic dysfunction associated steatotic liver disease is associated with an increased risk of multiple respiratory system diseases.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-96710-3

By:

Liu, Bofu;
Jia, Yu;
Gu, Zhihan;
Li, Yizhou;
Zhou, Yiheng;
Cao, Yu

Publication type:

Article

Frailty, genetic predisposition, and incident chronic kidney disease.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-97280-0

By:

Zou, Shanshan;
Sun, Ying;
Zhou, Yinuo;
Yu, Bowei;
Li, Jiang;
Yu, Yuefeng;
Chen, Jianing;
Li, Yujie;
Wang, Ningjian;
Wang, Li

Publication type:

Article

Comprehensive analysis of splicing variants in corneal endothelial cells of patients with Fuchs endothelial corneal dystrophy.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-92119-0

By:

Yuasa, Taichi;
Tokuda, Yuichi;
Nakano, Masakazu;
Tashiro, Kei;
Tourtas, Theofilos;
Schlötzer-Schrehardt, Ursula;
Kruse, Friedrich;
Koizumi, Noriko;
Okumura, Naoki

Publication type:

Article

Sex differences in predicting dyslipidemia using polygenic risk score with fatty liver index and fibrotic nonalcoholic steatohepatitis index.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-92766-3

By:

Kim, Sei;
Yoo, Hae Young

Publication type:

Article

Association of dietary carbohydrate ratio, caloric restriction, and genetic factors with breast cancer risk in a cohort study.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-90844-0

By:

Liu, Jiuyang;
Zhang, Ruizhe;
Ma, Lang;
Yang, Pin;
Wu, Zuyou;
Chen, Yalin;
Peng, Jingyi;
Yang, Xiaojun;
Huang, Chaoqun;
Yan, Jing

Publication type:

Article

EraSOR: a software tool to eliminate inflation caused by sample overlap in polygenic score analyses.

Published in:

GigaScience, 2023, v. 12, n. 1, p. 1, doi. 10.1093/gigascience/giad043

By:

Choi, Shing Wan;
Mak, Timothy Shin Heng;
Hoggart, Clive J;
O'Reilly, Paul F

Publication type:

Article

The utility of obesity polygenic risk scores from research to clinical practice: A review.

Published in:

Obesity Reviews, 2024, v. 25, n. 11, p. 1, doi. 10.1111/obr.13810

By:

Jansen, Philip R.;
Vos, Niels;
van Uhm, Jorrit;
Dekkers, Ilona A.;
van der Meer, Rieneke;
Mannens, Marcel M. A. M.;
van Haelst, Mieke M.

Publication type:

Article

Identification of a global gene expression signature associated with the genetic risk of catastrophic fracture in iPSC‐derived osteoblasts from Thoroughbred horses.

Published in:

Animal Genetics, 2025, v. 56, n. 1, p. 1, doi. 10.1111/age.13504

By:

Palomino Lago, Esther;
Ross, Amy K. C.;
McClellan, Alyce;
Guest, Deborah J.

Publication type:

Article

Copy-number variants and polygenic risk for intelligence confer risk for autism spectrum disorder irrespective of their effects on cognitive ability.

Published in:

Frontiers in Psychiatry, 2024, p. 1, doi. 10.3389/fpsyt.2024.1369767

By:

Schmilovich, Zoe;
Bourque, Vincent-Raphaël;
Douard, Elise;
Huguet, Guillaume;
Poulain, Cécile;
Ross, Jay P.;
Alipour, Paria;
Castonguay, Charles-Étienne;
Younis, Nadine;
Jean-Louis, Martineau;
Saci, Zohra;
Pausova, Zdenka;
Paus, Tomas;
Schuman, Gunter;
Porteous, David;
Davies, Gail;
Redmond, Paul;
Harris, Sarah E.;
Deary, Ian J.;
Whalley, Heather

Publication type:

Article

Genetics of psycho-emotional well-being: genome-wide association study and polygenic risk score analysis.

Published in:

Frontiers in Psychiatry, 2024, p. 1, doi. 10.3389/fpsyt.2023.1188427

By:

Yakovchik, Anna Yurievna;
Tolynyova, Darya V.;
Kashtanova, Daria A.;
Sutulova, Ekaterina R.;
Ivanov, Mikhail V.;
Mamchur, Alexandra A.;
Erema, Veronika V.;
Matkava, Lorena R.;
Terekhov, Mikhail V.;
Rumyantseva, Antonina M.;
Blinova, Olga I.;
Akinshina, Aleksandra I.;
Mitrofanov, Sergey I.;
Yudin, Vladimir S.;
Makarov, Valentin V.;
Keskinov, Anton A.;
Kraevoy, Sergey A.;
Yudin, Sergey M.

Publication type:

Article

Bidirectional Mendelian randomization analysis investigating the genetic association between primary breast cancer and colorectal cancer.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2023.1260941

By:

Yi Liu;
Mingxuan Si;
Yawei Qian;
Yang Liu;
Zichen Wang;
Tongyu Zhang;
Zhenhuan Wang;
Kun Ye;
Cuijuan Xiang;
Linlin Xu;
Yanping Zhang;
Zhihan Xiao

Publication type:

Article

Association of a composite trait for anthropometrics, adiposity and energy expenditure with cardiometabolic diseases: An age‐stratified cohort and genetic risk score analysis.

Published in:

Diabetes, Obesity & Metabolism, 2024, v. 26, n. 12, p. 5922, doi. 10.1111/dom.15966

By:

Meulmeester, Fleur L.;
van Dijk, Ko Willems;
van Heemst, Diana;
Noordam, Raymond

Publication type:

Article

Genetic variants of LEAP2 are associated with anthropometric traits and circulating insulin‐like growth factor‐1 concentration: A UK Biobank study.

Published in:

Diabetes, Obesity & Metabolism, 2024, v. 26, n. 9, p. 3565, doi. 10.1111/dom.15695

By:

Andreoli, María F.;
Gentreau, Mélissa;
Rukh, Gull;
Perello, Mario;
Schiöth, Helgi B.

Publication type:

Article

Smoking timing, genetic susceptibility and the risk of incident type 2 diabetes: A cohort study from the UK Biobank.

Published in:

Diabetes, Obesity & Metabolism, 2024, v. 26, n. 7, p. 2850, doi. 10.1111/dom.15603

By:

Hu, Ying;
Li, Xiang;
Wang, Xuan;
Ma, Hao;
Zhou, Jian;
Tang, Rui;
Kou, Minghao;
Heianza, Yoriko;
Liang, Zhaoxia;
Qi, Lu

Publication type:

Article