Works about DRUG target
Results: 5000
QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium.
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- CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 3, p. 561, doi. 10.1002/psp4.13296
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- Publication type:
- Article
Exogenously and Endogenously Sequential Regulation of DNA Nanodevices Enables Organelle‐Specific Signal Amplification in Subcellular ATP Profiling.
- Published in:
- Angewandte Chemie, 2025, v. 137, n. 12, p. 1, doi. 10.1002/ange.202422651
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- Publication type:
- Article
Conditional Relay Activation of Theranostic Prodrug by Pretargeting Bioorthogonal Trigger and Fluorescence‐Guided Visible Light Irradiation.
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- Angewandte Chemie, 2025, v. 137, n. 12, p. 1, doi. 10.1002/ange.202422023
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- Article
JAK2 is a critical therapeutic target in VEXAS syndrome treated with ruxolitinib.
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- British Journal of Haematology, 2025, v. 206, n. 2, p. 758, doi. 10.1111/bjh.19979
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- Article
CD71<sup>+</sup> erythroid cells promote multiple myeloma progression and impair anti‐bacterial immune response.
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- British Journal of Haematology, 2025, v. 206, n. 2, p. 478, doi. 10.1111/bjh.19914
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- Article
Targeting RNA modifications in leukaemia: Epitranscriptomic drugs are the new kids on the block.
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- British Journal of Haematology, 2025, v. 206, n. 2, p. 785, doi. 10.1111/bjh.19894
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- Article
Hydroxy‐wybutosine tRNA modifications as indicators of disease progression and therapeutic targets in leukaemia.
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- British Journal of Haematology, 2025, v. 206, n. 2, p. 517, doi. 10.1111/bjh.19873
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- Article
Downregulated STAT3 and STAT5B are prognostic biomarkers for colorectal cancer and are associated with immune infiltration.
- Published in:
- Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02085-2
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- Article
"Brain propane": Propionate Fuels the Brain in Mice With Brain Energy Deficits.
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- Epilepsy Currents, 2025, v. 25, n. 1, p. 70, doi. 10.1177/15357597241293843
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- Publication type:
- Article
Endometriosis and Sjögren's syndrome: Genetics insights on the observed bidirectional association of these diseases.
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- Acta Obstetricia et Gynecologica Scandinavica, 2025, v. 104, n. 2, p. 428, doi. 10.1111/aogs.14976
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- Article
Smoking, Genetic Susceptibility and Early Menopause: Unveiling Biological Mechanisms and Potential Therapy Targets.
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- BJOG: An International Journal of Obstetrics & Gynaecology, 2025, v. 132, n. 5, p. 625, doi. 10.1111/1471-0528.18052
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- Article
Deciphering the transcriptomic landscape of systemic lupus erythematosus-associated pulmonary arterial hypertension.
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- Respiratory Research, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12931-025-03169-x
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- Publication type:
- Article
Pan-cancer analysis and experimental verification of cytochrome B561 as a prognostic and therapeutic biomarker in breast cancer.
- Published in:
- Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02094-1
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- Publication type:
- Article
Artificial intelligence-driven integration of single-cell RNA sequencing and transcriptome analysis to decipher APOE's role in gastric cancer prognosis and therapy.
- Published in:
- Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02100-6
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- Publication type:
- Article
Type 2 Innate Lymphoid Cell in Cardiovascular Diseases: Complexities and Potentials.
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- Intensive Care Research, 2024, v. 4, n. 4, p. 210, doi. 10.1007/s44231-025-00078-x
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- Article
Gut integrity in intensive care: alterations in host permeability and the microbiome as potential therapeutic targets.
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- Journal of Intensive Care, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40560-025-00786-y
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- Publication type:
- Article
Multi-omics analysis identifies OSGEPL1 as an oncogene in hepatocellular carcinoma.
- Published in:
- Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02066-5
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- Publication type:
- Article
Electroencephalographic (EEG) Stages in Patients With Cerebral Edema Following Cardiac Arrest.
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- Journal of Child Neurology, 2025, v. 40, n. 3, p. 180, doi. 10.1177/08830738241289161
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- Publication type:
- Article
Prostaglandin E Receptor 2 (EP2) Dysregulation in Allergic Fungal Rhinosinusitis Nasal Polyp Epithelium.
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- Laryngoscope, 2025, v. 135, p. S1, doi. 10.1002/lary.31868
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- Publication type:
- Article
The role of lactate metabolism and lactylation in pulmonary arterial hypertension.
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- Respiratory Research, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12931-025-03163-3
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- Publication type:
- Article
Unveiling novel susceptibility genes and drug targets for basal cell carcinoma by a cross-tissue transcriptome-wide association study.
- Published in:
- Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02019-y
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- Publication type:
- Article
CPHNet: a novel pipeline for anti-HAPE drug screening via deep learning-based Cell Painting scoring.
- Published in:
- Respiratory Research, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12931-025-03173-1
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- Publication type:
- Article
Mitochondrial autophagy-related lncRNAs as prognostic biomarkers and therapeutic targets in gastric adenocarcinoma.
- Published in:
- Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02042-z
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- Publication type:
- Article
Comprehensive identification of hub mRNAs and lncRNAs in colorectal cancer using galaxy: an in silico transcriptome analysis.
- Published in:
- Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02026-z
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- Publication type:
- Article
Deciphering the metabolic landscape of colorectal cancer through the lens of AhR-mediated intestinal inflammation.
- Published in:
- Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01949-x
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- Publication type:
- Article
Prediction of drug target interaction based on under sampling strategy and random forest algorithm.
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- PLoS ONE, 2025, v. 20, n. 3, p. 1, doi. 10.1371/journal.pone.0318420
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- Article
Chronic RNA G-quadruplex accumulation in aging and Alzheimer's disease.
- Published in:
- eLife, 2025, p. 1, doi. 10.7554/eLife.105446
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- Publication type:
- Article
Lysine hydroxylase 1 (PLOD1) regulates glucose metabolism and promotes Th17 cell differentiation in psoriasis.
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- Allergologia & Immunopathologia, 2025, v. 53, n. 2, p. 1, doi. 10.15586/aei.v53i2.1269
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- Publication type:
- Article
Serum Exosomes miR-122-5P Induces Hepatic and Renal Injury in Septic Rats by Regulating TAK1/SIRT1 Pathway.
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- Infection & Drug Resistance, 2025, v. 18, p. 185, doi. 10.2147/IDR.S499643
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- Article
Virtual library docking for cannabinoid-1 receptor agonists with reduced side effects.
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- Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-57136-7
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- Publication type:
- Article
Advanced RPL19-TRAP<sup>KI</sup>-seq method reveals mechanism of action of bioactive compounds.
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- Natural Products & Bioprospecting, 2025, v. 15, n. 1, p. 1, doi. 10.1007/s13659-025-00500-3
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- Publication type:
- Article
Optimal Delivery of Pain Management in Schwannomatosis: A Literature Review.
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- Therapeutics & Clinical Risk Management, 2025, v. 21, p. 61, doi. 10.2147/TCRM.S362794
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- Article
NP-TCMtarget: a network pharmacology platform for exploring mechanisms of action of traditional Chinese medicine.
- Published in:
- Briefings in Bioinformatics, 2025, v. 26, n. 1, p. 1, doi. 10.1093/bib/bbaf078
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- Article
Therapeutic gene target prediction using novel deep hypergraph representation learning.
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- Briefings in Bioinformatics, 2025, v. 26, n. 1, p. 1, doi. 10.1093/bib/bbaf019
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- Article
Multimodal multiobjective optimization with structural network control principles to optimize personalized drug targets for drug discovery of individual patients.
- Published in:
- Briefings in Bioinformatics, 2025, v. 26, n. 1, p. 1, doi. 10.1093/bib/bbaf007
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- Publication type:
- Article
Proteomic Analysis of Transbronchial Biopsy Tissue Reveals a Distinct Proteome and Mechanistic Pathways in High-Grade Eosinophilic Inflammation After Lung Transplantation.
- Published in:
- 2025
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- Publication type:
- Letter
Pan-cancer characterization of C–C motif chemokine ligand 5 (CCL5) identifies its role as biomarker and therapeutic target.
- Published in:
- Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02004-5
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- Publication type:
- Article
Histone H3 lysine 9 tri-methylation is associated with pterygium.
- Published in:
- BMC Ophthalmology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12886-025-03939-7
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- Publication type:
- Article
Identification of plasma proteomic markers underlying polygenic risk of type 2 diabetes and related comorbidities.
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- Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56695-z
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- Publication type:
- Article
A Systematic Review of the Expression Pattern of Long Non-Coding RNAs SNHG5, SNHG17, and SNHG26 in Human Solid Tumors.
- Published in:
- Reviews in Clinical Medicine, 2024, v. 11, n. 4, p. 22, doi. 10.22038/rcm.2024.82201.1504
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- Publication type:
- Article
Spinal HDAC2 Influences the Development of Chronic Pancreatitis-Related Pain through mGluR2.
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- Journal of Evolutionary Biochemistry & Physiology, 2025, v. 61, n. 1, p. 358, doi. 10.1134/S0022093024600568
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- Publication type:
- Article
Active Components of Wen Fei Fu Yang Qu Tan Fang and its Molecular Targets for Chronic Obstructive Pulmonary Disease Based on Network Pharmacology and Molecular Docking.
- Published in:
- Cell Biochemistry & Biophysics, 2025, v. 83, n. 1, p. 657, doi. 10.1007/s12013-024-01498-0
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- Publication type:
- Article
Time to change guidelines? Suboptimal glycemic control measures by CGM associated with cystic fibrosis exacerbations despite adequate HbA1c.
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- Acta Diabetologica, 2025, v. 62, n. 3, p. 429, doi. 10.1007/s00592-025-02457-8
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- Article
Genomic diversity of mcr-carrying plasmids and the role of type IV secretion systems in IncI2 plasmids conjugation.
- Published in:
- Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07748-y
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- Publication type:
- Article
MurG as a potential target of quercetin in Staphylococcus aureus supported by evidence from subtractive proteomics and molecular dynamics.
- Published in:
- Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-90395-4
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- Publication type:
- Article
The role of telomere and telomerase in cancer and novel therapeutic target: narrative review.
- Published in:
- Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1542930
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- Publication type:
- Article
A high-throughput screening platform to identify MYCN expression inhibitors for liver cancer therapy.
- Published in:
- Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1486671
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- Publication type:
- Article
Targeting Spinal Interneurons for Respiratory Recovery After Spinal Cord Injury.
- Published in:
- Cells (2073-4409), 2025, v. 14, n. 4, p. 288, doi. 10.3390/cells14040288
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- Publication type:
- Article
Molecular Insights in Endometrial Stromal Sarcomas: Exploring New Targets for Novel Therapeutic Approaches.
- Published in:
- Biomolecules (2218-273X), 2025, v. 15, n. 2, p. 265, doi. 10.3390/biom15020265
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- Publication type:
- Article
Modulating PAK1: Accessory Proteins as Promising Therapeutic Targets.
- Published in:
- Biomolecules (2218-273X), 2025, v. 15, n. 2, p. 242, doi. 10.3390/biom15020242
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- Publication type:
- Article