Works about DRUG resistance in cancer cells

Results: 5000

Galectin-9 treatment is cytotoxic for B cell lymphoma by disrupting autophagy.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1601235

By:

Koll, Lisanne;
Lourens, Harm Jan;
Marsman, Glenn;
de Haan, Stan;
Niki, Toshiro;
Huls, Gerwin A.;
Bremer, Edwin;
Wiersma, Valerie R.

Publication type:

Article

The influence of homologous recombination repair on temozolomide chemosensitivity in gliomas.

Published in:

Carcinogenesis, 2025, v. 46, n. 2, p. 1, doi. 10.1093/carcin/bgaf017

By:

Zeng, Biyun;
Shi, Hansen;
Liu, Tiancai;
Tang, Jinjing;
Lin, Juncheng;
Lin, Xiaocong;
Zeng, Tao

Publication type:

Article

Multifaceted role of transgelin isoforms in cancer hallmarks.

Published in:

Carcinogenesis, 2025, v. 46, n. 2, p. 1, doi. 10.1093/carcin/bgaf014

By:

Jimenez, Ana Maria Jimenez;
Haddad, Yazan;
Jemelikova, Vendula;
Adam, Vojtech;
Rodrigo, Miguel Angel Merlos

Publication type:

Article

Chemoresistance and immune evasion in hepatocellular carcinoma: the role of miRNA-425-5p.

Published in:

Carcinogenesis, 2025, v. 46, n. 2, p. 1, doi. 10.1093/carcin/bgaf012

By:

Pan, Xinghe;
Liu, Junliang;
Zhang, Yitong;
Sun, Chenglin;
Li, You

Publication type:

Article

Role of the nucleotide excision repair function of CETN2 in the inhibition of the sensitivity of hepatocellular carcinoma cells to oxaliplatin.

Published in:

Carcinogenesis, 2025, v. 46, n. 2, p. 1, doi. 10.1093/carcin/bgaf003

By:

Tang, Hengcheng;
Zi, Huaduan;
Zhou, Donghu;
Li, Yanmeng;
Li, Xiaojin;
Chen, Zhibin;
Zhu, Qianyu;
Ouyang, Qin;
He, Pingping;
Chen, Sisi;
Li, Yanling;
Long, Jiang;
Huang, Jian

Publication type:

Article

C.2 Dexamethasone induced p57-mediated quiescence contributes to chemotherapy resistance in sonic hedgehog medulloblastoma.

Published in:

2025

By:

Sharma, A;
Purzner, J;
Purzner, T

Publication type:

Abstract

Establishing best practice in the Australian haematology setting for the use of chimeric antigen receptor T‐cell therapy for relapsed and refractory lymphoma.

Published in:

Internal Medicine Journal, 2025, v. 55, p. 4, doi. 10.1111/imj.16544

By:

Dickinson, Michael;
O'Leary, Nicole;
Hamad, Nada;
Cochrane, Tara;
Ho, P. Joy;
Cheah, Chan Y.;
Bishop, David;
Gregory, Gareth P.;
Butler, Jason;
Barraclough, Allison

Publication type:

Article

Extracellular Vesicles in cancer: from isolation and characterization to metastasis, drug resistance, and clinical applications.

Published in:

BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-025-14375-7

By:

Jurj, Ancuta;
Paul, Doru;
Calin, George A.

Publication type:

Article

ITM2A as a potential prognostic marker for triple-negative breast cancer.

Published in:

Journal of Cancer, 2025, v. 16, n. 9, p. 2903, doi. 10.7150/jca.114801

By:

Can Jiang;
Ruixin Feng;
Yongqian Zhao;
Jingting Zhang;
Na Han;
Yuzhu Zhang;
Guang Shu;
Gang Yin;
Maonan Wang

Publication type:

Article

Molecular and phenotypic characterization of 5-FU resistant colorectal cancer cells: toward enrichment of cancer stem cells.

Published in:

Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03758-2

By:

Babajnai, Amirhesam;
Rahmani, Saeed;
Asadi, Mohammad Jamal;
Gheytanchi, Elmira;
Adibhesami, Glavizh;
Vakhshiteh, Faezeh;
Madjd, Zahra

Publication type:

Article

CircASH1L inhibits ferroptosis and enhances cisplatin resistance by sponging miR-515-5p to regulate cell cycle-related CDCA7/RRM2 in ovarian cancer cells.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1563869

By:

Feng, Lu;
Zou, Xinru;
Tang, Longyu;
Yuan, Yijun;
He, Tianwen;
Su, Bin;
Tang, Ying;
Wang, Jiang;
Liu, Kang;
Li, Jun

Publication type:

Article

Reprogramming of glucose metabolism in pancreatic cancer: mechanisms, implications, and therapeutic perspectives.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1586959

By:

Zhang, Yan;
Li, Wancheng;
Niu, Jubao;
Fan, Zeyang;
Li, Xin;
Zhang, Hui

Publication type:

Article

SIRT5-modified human umbilical cord mesenchymal stem cells loaded with antioxidant polydopamine nanozyme enhance parpi resistance in ovarian cancer via fatty acid metabolism reprogramming.

Published in:

Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03516-6

By:

Zhang, Jin;
Du, Xiuluan;
Dai, Xin;
Liu, Yanxiang;
Guo, Kai;
Gu, Donghua

Publication type:

Article

Nuclear receptor subfamily 1 group D member 2 induces chemoresistance in ovarian cancer by regulating ferroptosis and immune infiltration.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03051-8

By:

Wang, Linlin;
Shao, Ning;
Qu, Yaoyu;
Sun, Huizhen;
Zhao, Jin

Publication type:

Article

OTUB1 promotes colorectal cancer progression by stabilizing GPX4 and inhibiting ferroptosis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03022-z

By:

Lin, Guofeng;
Lin, Xi;
Lin, Qihuang;
Zhao, Jianfeng

Publication type:

Article

Exosome-Mediated Mechanisms of Drug Resistance in Lung Cancer: Molecular Mechanisms and Therapeutic Strategies.

Published in:

Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2025, v. 59, n. 3, p. 358, doi. 10.33594/000000779

By:

Havryliuk, Vita;
Wojtowicz, Karolina;
Gagat, Maciej;
Żuryń, Agnieszka

Publication type:

Article

CRO-67 has anti-cancer activity in pancreatic tumor cells and stromal cancer-associated fibroblasts.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-09411-2

By:

Chiang, Shannon;
Garcia Netto, Keilah;
Kokkinos, John;
Haghighi, Koroush S.;
Raina, Aparna S.;
Youkhana, Janet;
Pitiyarachchi, Omali;
Truong, Quach;
Wenholz, Daniel;
Wilkinson, John;
Laczka, Olivier;
Li, Xiang;
Aldilla, Vina R.;
Kumar, Naresh;
Goldstein, David;
Sharbeen, George;
Phillips, Phoebe A.

Publication type:

Article

Metabolic alterations driven by LDHA in CD8 + T cells promote immune evasion and therapy resistance in NSCLC.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-87361-5

By:

Wen, Hao;
Zhang, Panpan;
Zhao, Juan;
Liu, Yakui;
Wan, Lei;
Li, Haoran;
Yi, Jun;
Li, Xinqiang

Publication type:

Article

Targeting the FOXA1/BMI1 axis to overcome chemoresistance and suppress tumor progression in nasopharyngeal carcinoma.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02595-6

By:

Qin, Yaping;
Yang, Mingqing;
Cao, Yunzhu;
Fu, Yue;
Yang, Fan;
Zhang, Xiaoling;
Xiao, Shengjun

Publication type:

Article

Tumor‐Specific On‐Site Activation of Cisplatin via Cascade Catalytic‐Redox Reactions for Highly Efficient Chemo‐Immunotherapy.

Published in:

Angewandte Chemie, 2025, v. 137, n. 28, p. 1, doi. 10.1002/ange.202500996

By:

Yang, Gang‐Gang;
Liu, Bin;
Liu, Wei;
Zhang, Lan;
Ke, Can;
Han, Xinya;
Cao, Qian;
Mao, Zong‐Wan

Publication type:

Article

Tripartite motif 47 promotes the development of thyroid carcinoma through ADAR ubiquitination.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01298-z

By:

Liu, Hongzhou;
Hu, Xiaodong;
Li, Tan;
Wang, Yuhan;
Fu, Xiaomin

Publication type:

Article

MCF-7 İnsan Meme Kanseri Hücre Soyunda Doksorubisin Öncesi ve Sonrası GST İzozimlerinin, İlaç Dirençlilik Proteinlerinin ve Apoptotik Etkisinin Araştırılması.

Published in:

Istanbul Gelisim University Journal of Health Sciences / İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi, 2020, n. 10, p. 1, doi. 10.38079/igusabder.631695

By:

KAYA KOÇDOĞAN, Arzu;
OĞUZTÜZÜN, Serpil;
GÜLER ŞİMŞEK, Gülçin;
TÜRK, Mustafa

Publication type:

Article

TRPV1 inhibition sensitizes tumors to PD-1 blockade by reversing resistance to CTL-mediated killing.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-07120-4

By:

Son, Min Kyu;
Lee, Hyo-Jung;
Cho, Eunho;
Oh, Se Jin;
Kim, Tae Woo

Publication type:

Article

Role of epithelial-to-mesenchymal transition and cancer stem cells in colorectal cancer.

Published in:

Oncology in Clinical Practice (2450-1654), 2025, v. 21, n. 3, p. 214, doi. 10.5603/ocp.99669

By:

Fudalej, Marta;
Mormul, Agata;
Deptała, Andrzej;
Badowska-Kozakiewicz, Anna M.

Publication type:

Article

Case Report: Metastatic colorectal cancer with ALK–CEP44 fusion and rapid resistance development.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1613235

By:

Hofmann, Silvan;
Egger, Claudine;
Potthast, Silke;
Zoche, Martin;
Wicki, Andreas;
Mehra, Tarun

Publication type:

Article

Application of single-cell and spatial omics in deciphering cellular hallmarks of cancer drug response and resistance.

Published in:

Journal of Hematology & Oncology, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13045-025-01722-1

By:

Cheng, Xiaoxia;
Peng, Ting;
Chu, Tian;
Yang, Yiqun;
Liu, Jia;
Gao, Qinglei;
Cao, Canhui;
Wei, Juncheng

Publication type:

Article

Long-term resident adipose-derived stromal stem cells in the microenvironment remodeling BLCA cell stemness and EMT promotes bladder cancer progression.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-07387-7

By:

Huang, Denggao;
Guo, Na;
Peng, Yanling;
Nie, Zhenyu;
Gao, Yuanhui;
Cao, Hui;
Wang, Shunlan;
Chen, Mei;
Wen, Xiaohong;
Wang, Zhaojun;
Zheng, Linlin;
He, Haowei;
Sun, Yong;
Chen, Yang;
Zhang, Shufang

Publication type:

Article

3 things you should know about advancing mCRPC care: Targeted sequencing, epigenetics, and emerging strategies.

Published in:: Urology Times, 2025, v. 53, n. 6, p. 26
Publication type:: Article

Resistance to MAPK Pathway Inhibition in BRAF -V600E Mutant Colorectal Cancer Can Be Overcome with Insulin Receptor/Insulin-like Growth Factor-1 Receptor Inhibitors.

Published in:

Organoids, 2025, v. 4, n. 2, p. 14, doi. 10.3390/organoids4020014

By:

El Bouazzaoui, Layla;
Raats, Daniëlle A. E.;
Verheem, André;
Rinkes, Inne H. M. Borel;
Snippert, Hugo J. G.;
Maurice, Madelon M.;
Kranenburg, Onno

Publication type:

Article

Applications and Prospects of Single‐Cell RNA Sequencing and Spatial Transcriptomics in Cervical Cancer.

Published in:

BioMed Research International, 2025, v. 2025, p. 1, doi. 10.1155/bmri/1532745

By:

Wang, Yifu;
Yang, Li;
Liu, Yunzhi;
Ma, Huangrong;
Cai, Miaoying;
Liang, Chunyu;
Zhang, Li;
Su, Zezhuo;
Xu, Zhiyuan;
Lopez-Camarillo, Cesar

Publication type:

Article

Prenylated Chalcones as Anticancer Agents Against Castration-Resistant Prostate Cancer.

Published in:

Scientia Pharmaceutica, 2025, v. 93, n. 2, p. 25, doi. 10.3390/scipharm93020025

By:

Morales-Reyna, Marcos;
Figueroa-Angulo, Elisa Elvira;
Espinoza-Hicks, José;
Camacho-Dávila, Alejandro;
López-Camarillo, César;
Vázquez-Carrillo, Laura Isabel;
Salgado-Aguayo, Alfonso;
Carlos-Reyes, Ángeles;
Álvarez-Jiménez, Violeta Deyanira;
Puente-Rivera, Jonathan;
Alvarez-Sánchez, María Elizbeth

Publication type:

Article

In reply to: "Letter to the editor in response to the article:'Squamous cell carcinoma arising in chronically damaged skin (Marjolijn's Ulcer)'".

Published in:

Oncologist, 2025, v. 30, n. 6, p. 1, doi. 10.1093/oncolo/oyaf161

By:

Miodovnik, Mor;
Dolev, Yardenna;
Buchen, Roni;
Brezis, Miriam Rivka;
Nikolaevski-Berlin, Alla;
Finkel, Inbar;
Wolf, Ido;
Ospovat, Inna;
Gutfeld, Orit;
Leshem, Yasmin

Publication type:

Article

KRAS mutated NSCLC: past, present, and future directions in a rapidly evolving landscape.

Published in:

Oncologist, 2025, v. 30, n. 6, p. 1, doi. 10.1093/oncolo/oyaf153

By:

Frisch, Austin;
Martin, Eric;
Kim, So Yeon;
Riess, Jonathan W;
Sen, Triparna;
Karim, Nagla

Publication type:

Article

A phase II, multicenter, single-arm study of pemigatinib in patients with metastatic or unresectable colorectal cancer harboring FGFR alterations.

Published in:

Oncologist, 2025, v. 30, n. 6, p. 1, doi. 10.1093/oncolo/oyaf069

By:

Wheless, Margaret C;
Zemla, Tyler J;
Hubbard, Joleen M;
Strickler, John H;
Gbolahan, Olumide B;
Wilson, Luke;
Waechter, Blake;
Ou, Fang-Shu;
Nixon, Andrew B;
Bekaii-Saab, Tanios S;
Ciombor, Kristen K

Publication type:

Article

Elacridar Inhibits BCRP Protein Activity in 2D and 3D Cell Culture Models of Ovarian Cancer and Re-Sensitizes Cells to Cytotoxic Drugs.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5800, doi. 10.3390/ijms26125800

By:

Stasiak, Piotr;
Sopel, Justyna;
Płóciennik, Artur;
Musielak, Oliwia;
Lipowicz, Julia Maria;
Rawłuszko-Wieczorek, Agnieszka Anna;
Sterzyńska, Karolina;
Korbecki, Jan;
Januchowski, Radosław

Publication type:

Article

Anticancer Potential of β-Sitosterol: A Comprehensive Exploration of Mechanisms and Therapeutic Prospects.

Published in:

American Journal of Chinese Medicine, 2025, v. 53, n. 4, p. 1241, doi. 10.1142/S0192415X2550048X

By:

Zhang, Yuzhe;
Yang, Chunjiao;
Guo, Junhan;
Yan, Lirong;
Li, Yanke;
Zhang, Ye

Publication type:

Article

Beyond Transposons: TIGD1 as a Pan-Cancer Biomarker and Immune Modulator.

Published in:

Genes, 2025, v. 16, n. 6, p. 674, doi. 10.3390/genes16060674

By:

Bal Albayrak, Merve Gulsen;
Korak, Tuğcan;
Akpinar, Gurler;
Kasap, Murat

Publication type:

Article

An overview of the relationship between melatonin and drug resistance in cancers.

Published in:

Hormone Molecular Biology & Clinical Investigation, 2025, v. 46, n. 2, p. 67, doi. 10.1515/hmbci-2025-0016

By:

Fazilat, Ahmad;
Roshani, Salomeh;
Moghadam, Fatemeh Mortazavi;
Valilo, Mohammad

Publication type:

Article

Crosstalk between miRNAs and signaling pathways in the development of drug resistance in breast cancer.

Published in:

Hormone Molecular Biology & Clinical Investigation, 2025, v. 46, n. 2, p. 47, doi. 10.1515/hmbci-2024-0066

By:

Amiri, Reza;
Nabi, Poorya Najjari;
Fazilat, Ahmad;
Roshani, Fatemeh;
Nouhi Kararoudi, Alireza;
Hemmati-Dinarvand, Mohsen;
Valilo, Mohammad

Publication type:

Article

HER2 Phosphorylation Is Maintained by a PKB Negative Feedback Loop in Response to Anti-HER2 Herceptin in Breast Cancer.

Published in:

PLoS Biology, 2010, v. 8, n. 12, p. 1, doi. 10.1371/journal.pbio.1000563

By:

Gijsen, Merel;
King, Peter;
Perera, Tim;
Parker, Peter J.;
Harris, Adrian L.;
Larijani, Banafshé;
Kong, Anthony

Publication type:

Article

Adaptive Amplification and Point Mutation Are Independent Mechanisms: Evidence for Various Stress-Inducible Mutation Mechanisms.

Published in:

PLoS Biology, 2004, v. 2, n. 11, p. 1, doi. 10.1371/journal.pbio.0020399

By:

Hastings, P. J;
Slack, Andrew;
Petrosino, Joseph F;
Rosenberg, Susan M

Publication type:

Article

Cabozantinib reverses multidrug resistance of human hepatoma HepG2/adr cells by modulating the function of P-glycoprotein.

Published in:

Liver International, 2015, v. 35, n. 3, p. 1010, doi. 10.1111/liv.12524

By:

Xiang, Qing‐feng;
Zhang, Dong‐mei;
Wang, Jing‐nan;
Zhang, Hong‐wu;
Zheng, Zhe‐yu;
Yu, Da‐cheng;
Li, Ying‐jie;
Xu, Jun;
Chen, Ya‐jin;
Shang, Chang‐zhen

Publication type:

Article

HBeAg-negative chronic hepatitis B: why do I treat my patients with nucleos(t)ide analogues.

Published in:

Liver International, 2009, v. 29, p. 130, doi. 10.1111/j.1478-3231.2008.01931.x

By:

Lampertico, Pietro;
Colombo, Massimo

Publication type:

Article

Molecular virology of hepatitis B virus and the development of antiviral drug resistance.

Published in:

Liver International, 2006, v. 26, p. 11, doi. 10.1111/j.1478-3231.2006.01371.x

By:

Locarnini, Stephen;
Omata, Masao

Publication type:

Article

LncRNA LINC00261 associates with chemoresistance and clinical prognosis in patients with epithelial ovarian cancer.

Published in:

Journal of Obstetrics & Gynaecology Research, 2024, v. 50, n. 12, p. 2271, doi. 10.1111/jog.16077

By:

Tian, Mei‐Ling;
Li, Bin;
Li, Yan;
Fan, Hong‐Wei;
Du, Nai‐Yi;
Kang, Shan

Publication type:

Article

Construction and validation of a prognostic model for overall survival time of patients with ovarian cancer by metabolism‐related genes.

Published in:

Journal of Obstetrics & Gynaecology Research, 2024, v. 50, n. 9, p. 1622, doi. 10.1111/jog.16044

By:

Kong, Deshui;
Guo, Hongyan

Publication type:

Article

The efficacy, safety, and beneficiary population of angiogenesis inhibitor apatinib plus chemotherapy in recurrent platinum‐resistant ovarian cancer patients: A comparative cohort study.

Published in:

Journal of Obstetrics & Gynaecology Research, 2024, v. 50, n. 8, p. 1345, doi. 10.1111/jog.15976

By:

Wu, Chunyan;
Yan, Jiali;
Wu, Yun

Publication type:

Article

Long‐term effect of letrozole on metastatic uterine smooth muscle tumors of uncertain malignant potential: A case report.

Published in:

Journal of Obstetrics & Gynaecology Research, 2023, v. 49, n. 11, p. 2771, doi. 10.1111/jog.15777

By:

Praben, Padiachy;
Kido, Hidenori;
Terao, Yasuhisa;
Takagi, Tatsuya;
Hayashi, Takuo;
Naito, Toshio;
Kato, Shunsuke

Publication type:

Article

Potential drug repurposing of ruxolitinib to inhibit the JAK/STAT pathway for the treatment of patients with epithelial ovarian cancer.

Published in:

Journal of Obstetrics & Gynaecology Research, 2023, v. 49, n. 11, p. 2563, doi. 10.1111/jog.15761

By:

Yunianto, Irfan;
Currie, Margaret;
Chitcholtan, Kenny;
Sykes, Peter

Publication type:

Article

SIK2: A critical glucolipid metabolic reprogramming regulator and potential target in ovarian cancer.

Published in:

Journal of Obstetrics & Gynaecology Research, 2023, v. 49, n. 8, p. 2000, doi. 10.1111/jog.15714

By:

Hu, Dan;
Du, JunHong;
Xing, YiJuan;
Cheng, YueMei;
He, RuiFen;
Liang, XiaoLei;
Li, HongLi;
Yang, YongXiu

Publication type:

Article