Works matching DE "DRUG development"

Results: 5000

An update on Linezolid resistance in Mycobacterium tuberculosis and the challenges ahead.

Published in:

Egyptian Journal of Chest Diseases & Tuberculosis, 2025, v. 74, n. 3, p. 267, doi. 10.4103/ecdt.ecdt_81_24

By:

Singh, Anupriya;
Chauhan, Varsha;
Kumar, Chanchal;
Varma-Basil, Mandira;
Prakash, Anupam

Publication type:

Article

A deep learning-based method for predicting the frequency classes of drug side effects based on multi-source similarity fusion Open Access.

Published in:

Bioinformatics, 2025, v. 41, n. 6, p. 1, doi. 10.1093/bioinformatics/btaf319

By:

Zhao, Haochen;
Li, Dingxi;
Zhong, Jian;
Liang, Xiao;
Duan, Guihua;
Wang, Jianxin

Publication type:

Article

Pharmaceutical Innovation Through Computational Drug Design: A Comprehensive Exploration.

Published in:

Makara Journal of Science, 2025, v. 29, n. 2, p. 216, doi. 10.7454/mss.v29i2.2629

By:

Chandramouli, Manasa;
Surendra, Madhusudhan Heggadadevanakote

Publication type:

Article

IAT + AHSCT - postavení vysokodávkované imunoablativní léčby s autologní transplantací hematopoetických kmenových buněk u pacientů s roztroušenou sklerózou.

Published in:

Neurologie Pro Praxi, 2025, v. 26, n. 3, p. 197, doi. 10.36290/neu.2025.010

By:

Hradílek, Pavel

Publication type:

Article

Quantitative Solid‐State NMR Spectroscopy (qSSNMR) in Pharmaceutical Analysis.

Published in:

Magnetic Resonance in Chemistry, 2025, v. 63, n. 8, p. 585, doi. 10.1002/mrc.5536

By:

Zheng, Zhaoxi;
Chen, Kang;
Liu, Yang;
Munson, Eric J.;
Su, Yongchao

Publication type:

Article

Treatment-related adverse events of antibody drug-conjugates in clinical trials.

Published in:

Journal of Hematology & Oncology, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13045-025-01720-3

By:

Tan, Harold Nathan;
Morcillo, Marta Ascanio;
Lopez, Juanita;
Minchom, Anna;
Sharp, Adam;
Paschalis, Alec;
Silva-Fortes, Georgina;
Raobaikady, Bindu;
Banerji, Udai

Publication type:

Article

Exploring the supraspinal antihyperalgesic effects of levetiracetam in the rat model of chronic constriction injury.

Published in:

Canadian Journal of Physiology & Pharmacology, 2025, v. 103, n. 7, p. 244, doi. 10.1139/cjpp-2024-0302

By:

Altinok, Feyza Alyu;
Petrella, Michele;
Masi, Alessio;
Borruto, Anna Maria;
Ciccocioppo, Roberto;
Ozturk, Yusuf

Publication type:

Article

SIMULATING NUCLEAR REACTIONS FOR OPTIMIZED PRODUCTION OF THERANOSTIC RADIONUCLIDES <sup>124</sup>I AND <sup>131</sup>I.

Published in:

Bayero Journal of Pure & Applied Sciences, 2024, v. 15, p. 264, doi. 10.4314/bajopas.v15i1.41S

By:

Zubaida, G. H.;
Koki, F. S.;
Ahmad, I.

Publication type:

Article

From Patents to Regulatory Exclusivities in Drug Development: A Comparative Transaction CostAnalysis.

Published in:

Jurimetrics: The Journal of Law, Science & Technology, 2024, v. 64, n. 4, p. 75

By:

Morgan, Maxwell;
Gold, E. Richard

Publication type:

Article

Anticancer effect of ethanolic yellow hawthorn extract on chronic myeloid leukemia cells and acute myeloid leukemia cells.

Published in:

Journal of Experimental & Clinical Medicine / Deneysel ve Klinik Tip Dergisi, 2025, v. 42, n. 2, p. 119, doi. 10.52142/omujecm.42.2.4

By:

ARSLAN, Ayşe Nur;
AKÇOK, İsmail

Publication type:

Article

Nanopore-based targeted sequencing (NTS) for drug-resistant tuberculosis: an integrated tool for personalized treatment strategies and guidance for new drug development.

Published in:

BMC Infectious Diseases, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12879-025-11227-4

By:

Yang, Chen;
Dai, Guangchuan;
Guo, Yicheng;
Wang, Tianzhen;
Gao, Weiwei;
Zeng, Yi

Publication type:

Article

AMCL: supervised contrastive learning with hard sample mining for multi-functional therapeutic peptide prediction.

Published in:

BMC Biology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12915-025-02273-0

By:

Fang, Jiwei;
Fan, Henghui;
Zhao, Jintao;
Zhao, Jianping;
Xia, Junfeng

Publication type:

Article

Joint fusion of sequences and structures of drugs and targets for identifying targets based on intra and inter cross-attention mechanisms.

Published in:

BMC Biology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12915-025-02256-1

By:

Zeng, Xin;
Su, Guang-Peng;
Du, Wen-Feng;
Jiang, Bei;
Li, Yi;
Yang, Zi-Zhong

Publication type:

Article

Single atom engineering for radiotherapy-activated immune agonist prodrugs.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60768-4

By:

Ding, Zexuan;
Yin, Xiaozhe;
Zheng, Yuedan;
Li, Yiyan;
Ge, Huanhuan;
Feng, Jianshu;
Wang, Ziyang;
Qiao, Simiao;
Sun, Qi;
Yu, Fashuo;
Hou, Zhanshan;
Fu, Yang-Xin;
Liu, Zhibo

Publication type:

Article

Phytochemical composition and bioactivity of Debregeasia saeneb leaves: Insights into anti-diabetic and antioxidant properties.

Published in:

PLoS ONE, 2025, v. 20, n. 7, p. 1, doi. 10.1371/journal.pone.0326991

By:

Khan, Rashid;
Afza, Rabia;
Ahmad, Bashir;
Miskeen, Sumaira;
Ahmad, Khalid;
Abdel-Maksoud, Mostafa A.;
Alrokayan, Salman;
Y. Zaky, Mohamed

Publication type:

Article

Financing drug development via adaptive platform trials.

Published in:

PLoS ONE, 2025, v. 20, n. 7, p. 1, doi. 10.1371/journal.pone.0325826

By:

Cho, Joonhyuk;
Sorets, Eugene;
Chaudhuri, Shomesh;
De Mattos, Annette;
Drake, Kristin;
Cudkowicz, Merit E.;
Ortiz, Ricardo;
Hasenoehrl, Meredith;
Chase, Marianne;
Harkey, Brittney;
Paganoni, Sabrina;
Frishkopf, John;
Lo, Andrew W.

Publication type:

Article

Overstating harms can have consequences.

Published in:

Brain: A Journal of Neurology, 2025, v. 148, n. 6, p. e52, doi. 10.1093/brain/awaf046

By:

Bedlack, Richard S

Publication type:

Article

Roadmap to Cytotoxicity: Exploring Assays and Mechanisms.

Published in:

Assay & Drug Development Technologies, 2025, v. 23, n. 5, p. 217, doi. 10.1089/adt.2024.109

By:

Shekhawat, Kirtivardhan Singh;
Bhatia, Piyush;
Bhatnagar, Kartik;
Shandilay, Swati;
Chaudhary, Sarika

Publication type:

Article

FAP inhibitors: are we really using the best method to evaluate the residence time?

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2025, v. 52, n. 9, p. 3062, doi. 10.1007/s00259-025-07160-y

By:

Cortesi, Michela;
Guerrini, Remo;
Roccatello, Chiara;
Pacifico, Salvatore;
Albanese, Valentina;
Ulivi, Paola;
Paganelli, Giovanni;
Bravaccini, Sara

Publication type:

Article

RESEARCH OF PHYSICOCHEMICAL, PHARMACOKINETIC AND DRUGLIKENESS PARAMETERS OF A SERIES OF 5-ARYLIDENE DERIVATIVES OF 3-(BENZO[d]THIAZOL-2-YLAMINO)-2-THIOXOTHIAZOLIDIN-4-ONE).

Published in:

Issues of Chemistry & Chemical Technology / Voprosy Khimii & Khimicheskoi Tekhnologii, 2025, n. 3, p. 4, doi. 10.32434/0321-4095-2025-160-3-4-12

By:

Mosula, L. M.;
Chudinovych, K. S.

Publication type:

Article

Viral hijacking of host DDX60 promotes Crimean-Congo haemorrhagic fever virus replication via G-quadruplex unwinding.

Published in:

PLoS Pathogens, 2025, v. 21, n. 6, p. 1, doi. 10.1371/journal.ppat.1013278

By:

Sui, Yutong;
Xu, Qi;
Liu, Mingsheng;
Liu, Xiaomei;
Liu, Xinpeng;
Wang, Yujie;
Meng, Xiangyuan;
Liu, Zinan;
Li, Quanshun;
Liu, Jinyu

Publication type:

Article

Bulk Measurement of Membrane Permeability for Random Cyclic Peptides in Living Cells to Guide Drug Development.

Published in:

Angewandte Chemie, 2025, v. 137, n. 27, p. 1, doi. 10.1002/ange.202500493

By:

Nielsen, Alexander L.;
Bartling, Christian R. O.;
Zarda, Anne;
De Sadeleer, Nathan;
Neeser, Rebecca M.;
Schwaller, Phillippe;
Strømgaard, Kristian;
Heinis, Christian

Publication type:

Article

BEHIND THE BREAKTHROUGHS: THE STRATEGIC RISE OF CONTRACT RESEARCH ORGANIZATIONS IN PHARMA.

Published in:

i-Manager's Journal on Life Sciences (JLS), 2025, v. 4, n. 1, p. 1, doi. 10.26634/jls.4.1.22064

By:

SADHANA, BONDILI

Publication type:

Article

Recent advancements in double-expressor lymphoma: novel therapeutic approaches and prospects.

Published in:

Oncologist, 2025, v. 30, n. 6, p. 1, doi. 10.1093/oncolo/oyaf085

By:

Zhuo, Yuejian;
Zhang, Dongdong

Publication type:

Article

Current Situation on Application of Evidence‐Based Pharmacy in National Drug Policy.

Published in:

Journal of Evidence-Based Medicine, 2025, v. 18, n. 2, p. 1, doi. 10.1111/jebm.70033

By:

Zeng, Linan;
Liu, Dan;
Zhang, Lingli;
Xiao, Wei;
Chen, Zhe;
Li, Hailong;
Diao, Sha;
Zou, Kun;
Yi, Qiusha

Publication type:

Article

From Bench to Bedside and Beyond: Shaping the Future of Early‐Phase Clinical Pharmacology at CPDD.

Published in:

Clinical Pharmacology in Drug Development, 2025, v. 14, n. 7, p. 490, doi. 10.1002/cpdd.1566

By:

Issa, Amalia M.

Publication type:

Article

Research progress of B7-H3 in malignant tumors.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1586759

By:

Zhao, Shuaixiang;
Zhang, He;
Shang, Guanning

Publication type:

Article

Unlocking the potential of tumor-targeting peptides in precision oncology.

Published in:

Oncology Research, 2025, v. 33, n. 7, p. 1547, doi. 10.32604/or.2025.062197

By:

REHMAN, HAFIZ MUHAMMAD;
AHMAD, SIDRA;
SARWAR, AZEEM;
BASHIR, HAMID

Publication type:

Article

Efficacy and Safety of Higher Doses of Levofloxacin for Multidrug-resistant Tuberculosis: A Randomized, Placebo-controlled Phase II Clinical Trial.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2025, v. 211, n. 7, p. 1277, doi. 10.1164/rccm.202407-1354OC

By:

Phillips, Patrick P. J.;
Peloquin, Charles A.;
Sterling, Timothy R.;
Kaur, Pawandeep;
Diacon, Andreas H.;
Gotuzzo, Eduardo;
Benator, Debra;
Warren, Robin M.;
Sikes, David;
Lecca, Leonid;
Gandhi, Neel R.;
Streicher, Elizabeth M.;
Dianis, Nancy;
Eisenach, Kathleen;
Mitnick, Carole D.;
Horsburgh Jr., C. Robert

Publication type:

Article

Exploration of Bioactive Compounds, Antioxidant and Antibacterial Properties, and Their Potential Efficacy Against HT29 Cell Lines in Dictyota bartayresiana.

Published in:

Marine Drugs, 2025, v. 23, n. 6, p. 224, doi. 10.3390/md23060224

By:

Bharathi, Durairaj Swarna;
Raja, Andiyappan Boopathy;
Nachimuthu, Suganthi;
Thangavel, S.;
Kannan, Karthik;
Shanmugan, Sengottaiyan;
Tari, Vinaya

Publication type:

Article

Synthesis of 1-(2-Hydroxy-5-methylphenyl)-5-oxopyrrolidine-3-carboxylic Acid Derivatives as a Promising Scaffold Against Disease-Causing Bacteria Relevant to Public Health.

Published in:

Molecules, 2025, v. 30, n. 12, p. 2639, doi. 10.3390/molecules30122639

By:

Krikštaponis, Karolis;
Šiugždaitė, Jūratė;
Vaickelionienė, Rita;
Mickevičius, Vytautas;
Grybaitė, Birutė

Publication type:

Article

Application of video surveillance in preclinical safety studies in canines: Understanding the interobserver reliability and validity to recognize clinical behavior.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0326916

By:

Eberhardt, Eline;
Tekle, Fetene;
Teuns, Greet;
Witters, Jill;
Feyen, Bianca;
De Landtsheer, Sarah;
Kopljar, Ivan

Publication type:

Article

Predicting trajectories of the north star ambulatory assessment total score in Duchenne muscular dystrophy.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0325736

By:

Muntoni, Francesco;
Signorovitch, James;
Goemans, Nathalie;
Manzur, Adnan Y.;
Done, Nicolae;
Sajeev, Gautam;
Li, Jiayang;
Akbarnejad, Hanane;
Sharma, Aarushi;
Ward, Susan J.;
Niks, Erik H.;
Servais, Laurant;
Mercuri, Eugenio;
Guglieri, Michela;
Straub, Volker;
de Groot, Imelda;
Ridout, Deborah;
McDonald, Craig

Publication type:

Article

Bibliometric Analysis of Research on Genus Etlingera: Insights into its Biomedical Applications.

Published in:

Malaysian Journal of Health Sciences / Jurnal Sains Kesihatan Malaysia, 2025, v. 23, n. 1, p. 44, doi. 10.17576/JSKM-2025-2301-01

By:

Annuar, Fazalda;
Noordin, Liza;
Nizam Wan Ahmad, Wan Amir;
Abu Bakar, Ainul Bahiyah;
Mat Zin, Anani Aila

Publication type:

Article

Evidence that minocycline treatment confounds the interpretation of neurofilament as a biomarker Open Access.

Published in:

Brain Communications, 2025, v. 7, n. 3, p. 1, doi. 10.1093/braincomms/fcaf175

By:

Gentile, Juliana E;
Heiss, Christina N;
Corridon, Taylor L;
Mortberg, Meredith A;
Fruhwürth, Stefanie;
Guzman, Kenia;
Grötschel, Lana;
Montoliu-Gaya, Laia;
Chan, Kwan;
Herring, Neil C;
Janicki, Timothy;
Nhass, Rajaa;
Sarathy, Janani Manavala;
Erickson, Brian;
Kunz, Ryan;
Erickson, Alison;
Braun, Craig;
Henry, Katherine T;
Bry, Lynn;
Arnold, Steven E

Publication type:

Article

Unraveling Nature's Pharmacy: Transforming Medicinal Plants into Modern Therapeutic Agents.

Published in:

Pharmaceutics, 2025, v. 17, n. 6, p. 754, doi. 10.3390/pharmaceutics17060754

By:

Vaou, Natalia;
Voidarou, Chrysoula;
Rozos, Georgios;
Saldari, Chrysa;
Stavropoulou, Elisavet;
Vrioni, Georgia;
Tsakris, Athanasios

Publication type:

Article

Preclinical Pharmacokinetic Evaluation of Mithramycin and Mithramycin SA Tryptophan-Conjugated Analog.

Published in:

Pharmaceutics, 2025, v. 17, n. 6, p. 765, doi. 10.3390/pharmaceutics17060765

By:

Niloy, Kumar Kulldeep;
Horn, Jamie;
Bhuiyan, Nazmul H.;
Shaaban, Khaled A.;
Bhosale, Suhas S.;
Prisinzano, Thomas E.;
Thorson, Jon S.;
Rohr, Jurgen;
Leggas, Markos

Publication type:

Article

Crossing the Blood–Brain Barrier: Innovations in Receptor- and Transporter-Mediated Transcytosis Strategies.

Published in:

Pharmaceutics, 2025, v. 17, n. 6, p. 706, doi. 10.3390/pharmaceutics17060706

By:

Ding, Ling;
Kshirsagar, Pratiksha;
Agrawal, Prachi;
Murry, Daryl J.

Publication type:

Article

Beyond ADME: The Endogenous Functions of Drug Transporters and Its Impact on Human Disease.

Published in:

Pharmaceutics, 2025, v. 17, n. 6, p. 685, doi. 10.3390/pharmaceutics17060685

By:

Blaze, Christine;
Shu, Yan

Publication type:

Article

M. avium Complex Pulmonary Infections: Therapeutic Obstacles and Progress in Drug Development.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 891, doi. 10.3390/ph18060891

By:

Charrier, Elise Si Ahmed;
Dassonville-Klimpt, Alexandra;
Andréjak, Claire;
Sonnet, Pascal

Publication type:

Article

Identification of Inhibitors with Potential Anti-Prostate Cancer Activity: A Chemoinformatics Approach.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 888, doi. 10.3390/ph18060888

By:

Costa, Norberto S.;
Lima, Lúcio R.;
Cruz, Jorddy N.;
Santos, Igor V. F.;
Silva, Rai C.;
Maciel, Alexandre A.;
Barros, Elcimar S.;
Andrade, Maracy L. D. S.;
Ramos, Ryan S.;
Kimani, Njogu M.;
Aragón-Muriel, Alberto;
Álvarez-Caballero, Juan M.;
Campos, Joaquín M.;
Santos, Cleydson B. R.

Publication type:

Article

Discovery of Small-Molecule Inhibitors Against Norovirus 3CL pro Using Structure-Based Virtual Screening and FlipGFP Assay.

Published in:

Viruses (1999-4915), 2025, v. 17, n. 6, p. 814, doi. 10.3390/v17060814

By:

Shen, Hao;
Liu, Shiqi;
Shang, Limin;
Liu, Yuchen;
Sha, Yijin;
Lei, Dingwei;
Zhang, Yuehui;
Jin, Chaozhi;
Wu, Shanshan;
Zhang, Mingyang;
Wen, Han;
Jia, Chenxi;
Wang, Jian

Publication type:

Article

Ketamine for rapid sequence induction in patients with head injury in the emergency department.

Published in:

Emergency Medicine Australasia, 2006, v. 18, n. 1, p. 37, doi. 10.1111/j.1742-6723.2006.00802.x

By:

Sehdev, Rajesh S.;
Symmons, David A. D.;
Kindl, Korana

Publication type:

Article

Incretins: How we got here, where we're at and what is coming next.

Published in:

Journal of Diabetes Nursing, 2024, v. 28, n. 1, p. 1

By:

Morris, David

Publication type:

Article

网络药理学在食疗护理相关研究中的应用进展.

Published in:

Chinese Nursing Research, 2022, v. 36, n. 7, p. 1180, doi. 10.12102/j.issn.1009-6493.2022.07.011

By:

韩世范;
朱瑞芳;
陈雨露;
曹妍;
冯耀清;
张倩;
程俊香;
张珺

Publication type:

Article

Cutting Canada's drug approval delay while improving safety.

Published in:

Fraser Forum, 2013, p. 24

By:

Esmail, Nadeem

Publication type:

Article

Editor's notes.

Published in:

Fraser Forum, 2006, p. 2

By:

McCahon, Kristin

Publication type:

Article

Merck Labs Illustrate Why New Drugs Cost Money.

Published in:

Fraser Forum, 2005, p. 25

By:

Murdock, Deroy

Publication type:

Article

Antibacterial activity and synergism of the essential oil of Nectandra megapotamica (L.) flowers against OXA-23-producing Acinetobacter baumannii.

Published in:

Journal of Essential Oil Research, 2020, v. 32, n. 3, p. 260, doi. 10.1080/10412905.2020.1740802

By:

Vasconcelos, Nathalie Gaebler;
Mallmann, Viviane;
Costa, Érica Rodrigues;
Simionatto, Euclésio;
Coutinho, Eduardo João;
De Lara Da Silva, Rogério César;
Ribeiro, Suzana Meira;
Franco, Octávio Luiz;
Migliolo, Ludovico;
Croda, Júlio;
Simionatto, Simone

Publication type:

Article

HIV-1 assembly, release and maturation.

Published in:

Nature Reviews Microbiology, 2015, v. 13, n. 8, p. 484, doi. 10.1038/nrmicro3490

By:

Freed, Eric O.

Publication type:

Article