Works about DNA topoisomerase II

Results: 1513

Antibacterial Activity and Molecular Docking of Lignans Isolated from Artemisia cina Against Multidrug-Resistant Bacteria.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 781, doi. 10.3390/ph18060781

By:

García Hernández, Leslie Cynthia;
Higuera-Piedrahita, Rosa Isabel;
Rivero-Perez, Nallely;
Morales-Ubaldo, Ana Lizet;
Valladares-Carranza, Benjamín;
de la Cruz-Cruz, Héctor Alejandro;
Cuéllar-Ordaz, Jorge Alfredo;
González-Ruiz, Cynthia;
Nicolás-Vázquez, María Inés;
Zaragoza-Bastida, Adrian

Publication type:

Article

Species-Specific Heterochromatin Prevents Mitotic Chromosome Segregation to Cause Hybrid Lethality in Drosophila.

Published in:

PLoS Biology, 2009, v. 7, n. 10, p. 1, doi. 10.1371/journal.pbio.1000234

By:

Ferree, Patrick M.;
Barbash, Daniel A.

Publication type:

Article

Dual Role of Topoisomerase II in Centromere Resolution and Aurora B Activity.

Published in:

PLoS Biology, 2008, v. 6, n. 8, p. e207, doi. 10.1371/journal.pbio.0060207

By:

Coelho, Paula A.;
Queiroz-Machado, Joana;
Carmo, Alexandre M.;
Moutinho-Pereira, Sara;
Maiato, Helder;
Sunkel, Claudio E.

Publication type:

Article

A New Role for a Long-Studied DNA-Wrangling Enzyme.

Published in:

PLoS Biology, 2008, v. 6, n. 8, p. e218, doi. 10.1371/journal.pbio.0060218

By:

Gross, Liza

Publication type:

Article

Long-term exposure to irinotecan reduces cell migration in glioma cells.

Published in:

Journal of Neuro-Oncology, 2016, v. 127, n. 3, p. 455, doi. 10.1007/s11060-016-2058-4

By:

Al-Ghafari, A.;
Punjaruk, W.;
Storer, L.;
Carrier, D.;
Hussein, D.;
Coyle, B.;
Kerr, I.

Publication type:

Article

Clinical trial of CPT-11 and VM-26/VP-16 for patients with recurrent malignant brain tumors.

Published in:

Journal of Neuro-Oncology, 2007, v. 82, n. 2, p. 177, doi. 10.1007/s11060-006-9261-7

By:

Lynn Feun;
Angela Marini;
Howard Landy;
Arnold Markoe;
Deborah Heros;
Carlos Robles;
Cristina Herrera;
Niramol Savaraj

Publication type:

Article

Progression of chromosomal damage induced by etoposide in G2 phase in a DNA-PKcs-deficient context.

Published in:

Chromosome Research, 2015, v. 23, n. 4, p. 719, doi. 10.1007/s10577-015-9478-4

By:

Palmitelli, Micaela;
Campos-Nebel, Marcelo;
González-Cid, Marcela

Publication type:

Article

How to be a mitotic chromosome.

Published in:

Chromosome Research, 2011, v. 19, n. 3, p. 307, doi. 10.1007/s10577-011-9198-3

By:

Moser, Sandra;
Swedlow, Jason

Publication type:

Article

TOP2A deficiency leads to human recurrent spontaneous abortion and growth retardation of mouse pre-implantation embryos.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00592-4

By:

Duan, Yuhan;
Fu, Huijia;
Huang, Jiayu;
Yin, Nanlin;
Liu, Linhong;
Liu, Xiru

Publication type:

Article

Synthesis, Cytotoxic Activity, Antiquorum Sensing Effect, Docking and Md Simulation of Novel 1,3‐Disubstituted 2‐Mercapto‐1H‐Benzo[D]Imidazolium Chlorides.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 4, p. 1, doi. 10.1002/jbt.70248

By:

Mavvaji, Mohammad;
Muhammed, Muhammed Tilahun;
Onem, Ebru;
Aslan, Halime Güzin;
Alhag, Sadeq K.;
Akkoc, Senem

Publication type:

Article

Elucidating the interplay of PPAR gamma inhibition and energy demand in adriamycin‐induced cardiomyopathy: In Vitro and In Vivo perspective.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 10, p. 1, doi. 10.1002/jbt.23855

By:

Seenivasan, Kalaiselvi;
Arunachalam, Sankarganesh;
P. B., Tirupathi Pichiah;
Vasan, Sanjay B.;
Venkateswaran, Meenakshi R.;
Siva, Durairaj;
Gothandam, Jeeva;
Achiraman, Shanmugam

Publication type:

Article

Unveiling the antibacterial efficacy of thiazolo [3,2‐a] pyrimidine: Synthesis, molecular docking, and molecular dynamic simulation.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 9, p. 1, doi. 10.1002/jbt.23822

By:

Patel, Vishant C.;
Patel, Ankit J.;
Patel, Darshan S.;
Dholakia, Amit B.;
Ansari, Siddique Akber;
Agrawal, Mohit

Publication type:

Article

Benzimidazole and piperidine containing novel 1,2,3‐triazole hybrids as anti‐infective agents: Design, synthesis, in silico and in vitro antimicrobial efficacy.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 1, p. 1, doi. 10.1002/jbt.23526

By:

Mendapara, Jigarkumar V.;
Vaghasiya, Mahesh D.;
Rajani, Dhanji P.;
Ahmad, Iqrar;
Patel, Harun;
Kumari, Premlata

Publication type:

Article

Synthesis, molecular docking, ADME study, and antimicrobial potency of piperazine based cinnamic acid bearing coumarin moieties as a DNA gyrase inhibitor.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 1, p. 1, doi. 10.1002/jbt.23231

By:

Zala, Ajayrajsinh R.;
Rajani, Dhanji P.;
Kumari, Premlata

Publication type:

Article

Preparation, DFT calculations, docking studies, antioxidant, and anticancer properties of new pyrazole and pyridine derivatives.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 9, p. 1, doi. 10.1002/jbt.23135

By:

Zebbiche, Zineddine;
Şekerci, Güldeniz;
Boulebd, Houssem;
Küçükbay, Fatümetüzzehra;
Tekin, Suat;
Tekin, Zehra;
Küçükbay, Hasan;
Sandal, Süleyman;
Boumoud, Boudjemaa

Publication type:

Article

Detection and identification of Escherichia coli, Shigella, and Salmonella by microarrays using the gyrB gene.

Published in:

Biotechnology & Bioengineering, 2003, v. 83, n. 6, p. 721, doi. 10.1002/bit.10709

By:

Kenichi Kakinuma;
Masao Fukushima;
Ryuji Kawaguchi

Publication type:

Article

DNA Topoisomerase II modulates acetyl-regulation of cohesin-mediated chromosome dynamics.

Published in:

Current Genetics, 2017, v. 63, n. 5, p. 923, doi. 10.1007/s00294-017-0691-x

By:

Lin, Su-Jiun;
O'Connell, Matthew

Publication type:

Article

Squaring up to DNA: pentapeptide repeat proteins and DNA mimicry.

Published in:

Applied Microbiology & Biotechnology, 2014, v. 98, n. 23, p. 9545, doi. 10.1007/s00253-014-6151-3

By:

Shah, Shama;
Heddle, Jonathan

Publication type:

Article

Exploiting bacterial DNA gyrase as a drug target: current state and perspectives.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 92, n. 3, p. 479, doi. 10.1007/s00253-011-3557-z

By:

Collin, Frédéric;
Karkare, Shantanu;
Maxwell, Anthony

Publication type:

Article

Rearrangement of the Myeloid/Lymphoid Leukemia Gene in Therapy-Related Myelodysplastic Syndrome in Patients Previously Treated with Agents Targeting DNA Topoisomerase II.

Published in:

Oncology, 2012, v. 83, n. 3, p. 128, doi. 10.1159/000338769

By:

Mosad, Eman;
Abdou, Madleen;
Zaky, Amen Hamdy

Publication type:

Article

Tumor Topoisomerase II Alpha Status and Response to Anthracycline-Based Neoadjuvant Chemotherapy in Breast Cancer.

Published in:

Oncology, 2011, v. 80, n. 3/4, p. 269, doi. 10.1159/000329038

By:

Nikolényi, Alíz;
Sükösd, Farkas;
Kaizer, László;
Csörgő, Erika;
Vörös, András;
Uhercsák, Gabriella;
Ormándi, Katalin;
Lázár, György;
Thurzó, László;
Brodowicz, Thomas;
Kahán, Zsuzsanna

Publication type:

Article

Targeting Her-2/neu in Breast Cancer: As Easy as This!

Published in:

Oncology, 2008, v. 74, n. 3/4, p. 150, doi. 10.1159/000151362

By:

Azim, Hamdy;
Azim Jr., Hatem A.

Publication type:

Article

Pyrazine Linked 1,3,4-Oxadiazoles as DNA Gyrase Inhibitors: In silico Design, Molecular Docking, MM-GBSA Assay, MD Simulations and ADMET Studies.

Published in:

Journal of Computational Biophysics & Chemistry, 2025, v. 24, n. 8, p. 1063, doi. 10.1142/S2737416525500103

By:

Ranjan, Venkatesh;
Revanasiddappa, B. C.;
Prasanth, S.;
Bhat, Nanditha;
Bidye, Durgesh Paresh;
Dixit, Sheshagiri R.;
Pai, Aravinda

Publication type:

Article

In Silico Molecular Docking Approach and In Vitro Antioxidant and Antimicrobial Activity of Physalis angulata L. Extract.

Published in:

Journal of Computational Biophysics & Chemistry, 2024, v. 23, n. 2, p. 161, doi. 10.1142/S2737416523500564

By:

Wardhani, Riuh;
Darsih, Cici;
Iwansyah, Ade Chandra;
Indriati, Ashri;
Hamid, Hazrulrizawati Abdul;
Husain, Dirayah Rauf

Publication type:

Article

In Silico Studies, Design and Synthesis of Novel Fused Pyrimidine Derivatives as a DNA Gyrase Inhibitor and Antibacterial Activity Against Quinolone Resistant Escherichia Coli.

Published in:

Journal of Computational Biophysics & Chemistry, 2023, v. 22, n. 6, p. 687, doi. 10.1142/S2737416523500357

By:

Bhandare, Richie R.;
Helina, N.;
Subramani, Arun kumar;
Natarajan, Ramalakshmi;
Mali, Suraj N.;
Shaik, Afzal B.

Publication type:

Article

Anti-proliferative impact of three Schiff base platinum (II) complexes against human breast cancer cell line.

Published in:

Journal of Research in Pharmacy, 2022, v. 26, n. 6, p. 1665, doi. 10.29228/jrp.257

By:

BAZSEFIDPAR, Parisa;
ZOLGHADRI, Samaneh;
NIKPOOR, Amin Reza;
EFTEKHAR, Ebrahim;
ZAREIAN JAHROMI, Mohammad

Publication type:

Article

The first facile optical density-dependent approach for the analysis of doxorubicin, an oncogenic agent accompanied with the co-prescribed drug; paclitaxel.

Published in:

BMC Chemistry, 2023, v. 17, n. 1, p. 1, doi. 10.1186/s13065-023-00976-5

By:

Hamad, Ahmed Abdulhafez

Publication type:

Article

Antibacterial and antioxidant activities of extracts and isolated compounds from the roots extract of Cucumis prophetarum and in silico study on DNA gyrase and human peroxiredoxin 5.

Published in:

BMC Chemistry, 2021, v. 15, n. 1, p. 1, doi. 10.1186/s13065-021-00758-x

By:

Galma, Wario;
Endale, Milkyas;
Getaneh, Emebet;
Eswaramoorthy, Rajalakshmanan;
Assefa, Temesgen;
Melaku, Yadessa

Publication type:

Article

获能前后水牛精子的差异蛋白质组分析.

Published in:

Journal of Henan Agricultural Sciences, 2022, v. 51, n. 5, p. 140, doi. 10.15933/j.cnki.1004-3268.2022.05.015

By:

刘润峰;
候振;
黄星晨;
肖凯;
杨潍菡;
张俊俊;
付强

Publication type:

Article

Comparison of Clinical Manifestations, Antimicrobial Susceptibility Patterns, and Mutations of Fluoroquinolone Target Genes between Elizabethkingia meningoseptica and Elizabethkingia anophelis Isolated in Taiwan.

Published in:

Journal of Clinical Medicine, 2018, v. 7, n. 12, p. 538, doi. 10.3390/jcm7120538

By:

Lin, Jiun-Nong;
Lai, Chung-Hsu;
Yang, Chih-Hui;
Huang, Yi-Han

Publication type:

Article

Investigation of plasmid-mediated quinolone resistance genes in carbapenem resistant Enterobacterales.

Published in:

Journal of Experimental & Clinical Medicine / Deneysel ve Klinik Tip Dergisi, 2022, v. 39, n. 2, p. 429, doi. 10.52142/omujecm.39.2.23

By:

TANRIVERDİ ÇAYCI, Yeliz;
BIYIK, İlknur;
BİLGİN, Kemal;
VURAL, Demet GÜR;
BİRİNCİ, Asuman

Publication type:

Article

در سویۀ جهشیافتۀ اشریشیا کلی با مقاومت زیاد به سیپروفلوکسازین rpoS بیان ژن.

Published in:

Biological Journal of Microorganism, 2020, v. 9, n. 33, p. 14, doi. 10.22108/BJM.2020.119666.1230

By:

ملیکاااااا اااا&;
راضاایه اورا ااا;
مح رضا محزونیاه

Publication type:

Article

POSSIBLE CARDIOPROTECTIVE MECHANISM OF ACTION OF DEXRAZOXANE, AND PROBABLE HUMAN TOPOISOMERASE IIß INHIBITORS: AN IN SILICO ANALYSIS.

Published in:

Journal of Faculty of Pharmacy of Ankara University / Ankara Üniversitesi Eczacilik Fakültesi Dergisi, 2022, v. 46, n. 2, p. 474, doi. 10.33483/jfpau.1085504

By:

KARAKUŞ, Fuat;
KUZU, Burak

Publication type:

Article

A Detailed Analysis of Codon Usages Bias and Affecting Factors in the Topoisomerase II Gene of Invertebrate iridescent virus 6.

Published in:

Afyon Kocatepe University Journal of Science & Engineering / Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi, 2024, v. 24, n. 3, p. 492, doi. 10.35414/akufemubid.1388197

By:

DİZMAN, Yeşim AKTÜRK

Publication type:

Article

Rapid, DNA-induced interface swapping by DNA gyrase.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.86722

By:

Germe, Thomas R. M.;
Bush, Natassja G.;
Baskerville, Victoria M.;
Saman, Dominik;
Benesch, Justin L. P.;
Maxwell, Anthony

Publication type:

Article

Antitumor activities on HL-60 human leukemia cell line, molecular docking, and quantum-chemical calculations of some sulfonamide-benzoxazoles.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2017, v. 45, n. 7, p. 1388, doi. 10.1080/21691401.2016.1241796

By:

Oksuzoglu, Emine;
Ertan-Bolelli, Tugba;
Can, Hatice;
Tarhan, Mehtap;
Ozturk, Kamile;
Yildiz, Ilkay

Publication type:

Article

Novel dual action chimera doxorubizen demonstrates superior efficacy to doxorubicin in acute leukemia.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-94373-8

By:

Walunj, Dipak;
Egarmina, Katarina;
Zipin-Roitman, Adi;
Muddineni, Siva Sai Naga Anurag;
Tkachenko, Iryna;
Mitra, Pousali;
Tobi, Dror;
Bazylevich, Andrii;
Shpilberg, Ofer;
Milyavsky, Michael;
Hershkovitz-Rokah, Oshrat;
Gellerman, Gary

Publication type:

Article

DNA topoisomerases as targets for anticancer drugs.

Published in:

Journal of Clinical Pharmacy & Therapeutics, 2001, v. 26, n. 6, p. 405, doi. 10.1046/j.1365-2710.2001.00368.x

By:

Z.;
Topcu, Z.

Publication type:

Article

Identification of Hub Genes Associated With Immune Infiltration and Predict Prognosis in Hepatocellular Carcinoma via Bioinformatics Approaches.

Published in:

Frontiers in Genetics, 2021, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.575762

By:

Chen, Huaping;
Wu, Junrong;
Lu, Liuyi;
Hu, Zuojian;
Li, Xi;
Huang, Li;
Zhang, Xiaolian;
Chen, Mingxing;
Qin, Xue;
Xie, Li

Publication type:

Article

Synthesis, antimicrobial screening, and docking study of new 2‐(2‐ethylpyridin‐4‐yl)‐4‐methyl‐N‐phenylthiazole‐5‐carboxamide derivatives.

Published in:

Journal of the Chinese Chemical Society, 2021, v. 68, n. 2, p. 353, doi. 10.1002/jccs.202000174

By:

Kasare, Sanghratna L.;
Gund, Pornima N.;
Sathe, Bhaurao P.;
Patil, Pravin S.;
Rehman, Naziya N. M. A.;
Dixit, Prashant P.;
Choudhari, Prafulla B.;
Haval, Kishan P.

Publication type:

Article

Discovery of a more potent anticancer agent than C4‐benzazole 1,8‐naphthalimide derivatives against murine melanoma.

Published in:

Journal of the Chinese Chemical Society, 2020, v. 67, n. 7, p. 1254, doi. 10.1002/jccs.202000019

By:

Tung, Chi‐Hua;
Lu, Yen‐Ta;
Kao, Wei‐Ting;
Liu, Jen‐Wei;
Lai, Yi‐Hsuan;
Jiang, Shinn‐Jong;
Chen, Hao‐Ping;
Shih, Tzenge‐Lien

Publication type:

Article

Inhibition of cardiac HERG currents by the DNA topoisomerase II inhibitor amsacrine: mode of action.

Published in:

2004

By:

Thomas, Dierk;
Hammerling, Bettina C.;
Kezhong Wu;
Wimmer, Anna-Britt;
Ficker, Eckhard K.;
Kirsch, Glenn E.;
Cochan, Mary C.;
Wible, Barbara A.;
Scholz, Eberhard P.;
Zitron, Edgar;
Kathöfer, Sven;
Kreye, Volker A.W.;
Katus, Hugo A.;
Schoels, Wolfgang;
Karle, Cristoph A.;
Kiehn, Johann;
Wu, Kezhong;
Kochan, Mary C;
Kathöfer, Sven;
Karle, Christoph A

Publication type:

journal article

Osmotic disruption of chromatin induces Topoisomerase 2 activity at sites of transcriptional stress.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-54567-6

By:

Gittens, William H.;
Allison, Rachal M.;
Wright, Ellie M.;
Brown, George G. B.;
Neale, Matthew J.

Publication type:

Article

BWC0977, a broad-spectrum antibacterial clinical candidate to treat multidrug resistant infections.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52557-2

By:

Hameed P, Shahul;
Kotakonda, Harish;
Sharma, Sreevalli;
Nandishaiah, Radha;
Katagihallimath, Nainesh;
Rao, Ranga;
Sadler, Claire;
Slater, Ian;
Morton, Michael;
Chandrasekaran, Abhijeeth;
Griffen, Ed;
Pillai, Dhanashree;
Reddy, Sambasiva;
Bharatham, Nagakumar;
Venkatesan, Suryanarayanan;
Jonnalagadda, Venugopal;
Jayaraman, Ramesh;
Nanjundappa, Mahesh;
Sharma, Maitrayee;
Raveendran, Savitha

Publication type:

Article

Inhibition of topoisomerase 2 catalytic activity impacts the integrity of heterochromatin and repetitive DNA and leads to interlinks between clustered repeats.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49816-7

By:

Amoiridis, Michalis;
Verigos, John;
Meaburn, Karen;
Gittens, William H.;
Ye, Tao;
Neale, Matthew J.;
Soutoglou, Evi

Publication type:

Article

Development and validation of stability indicating RP-HPLC method for estimation of Garenoxacin Mesylate in tablet dosage form.

Published in:

International Journal of Pharmacy & Life Sciences, 2017, v. 8, n. 3, p. 5504

By:

Panchal, Ashwinkumar B.;
Patel, Bhumi R.;
Patel, Jaymin G.;
Patel, Yogesh K.;
Maurya, Udayshankar J.

Publication type:

Article

HToPred: A Tool for Human Topoisomerase II Inhibitor Prediction.

Published in:

Molecular Informatics, 2019, v. 38, n. 1/2, p. N.PAG, doi. 10.1002/minf.201800046

By:

Tripathi, Neha;
Shaikh, Naeem;
Bharatam, Prasad V.;
Garg, Prabha

Publication type:

Article

Computational Approaches to Develop Isoquinoline Based Antibiotics through DNA Gyrase Inhibition Mechanisms Unveiled through Antibacterial Evaluation and Molecular Docking.

Published in:

Molecular Informatics, 2018, v. 37, n. 12, p. N.PAG, doi. 10.1002/minf.201800048

By:

Alagumuthu, Manikandan;
Muralidharan, Vivek Panyam;
Andrew, Monic;
Ahmed, Mohammed Habeeb;
Iyer, Sathiyanarayanan Kulathu;
Arumugam, Sivakumar

Publication type:

Article

Repositioning of Endonuclear Receptors Binders as Potential Antibacterial and Antifungal Agents. Eptyloxìm: A Potential and Novel Gyrase B and Cytochrome Cyp51 Inhibitor.

Published in:

Molecular Informatics, 2016, v. 35, n. 8/9, p. 326, doi. 10.1002/minf.201600021

By:

Carrieri, Antonio;
L'Abbate, Maria;
Di Chicco, Mariangela;
Rosato, Antonio;
Carbonara, Giuseppe;
Fracchiolla, Giuseppe

Publication type:

Article

Discovery of Novel Mycobacterial DNA Gyrase B Inhibitors: In Silico and In Vitro Biological Evaluation.

Published in:

Molecular Informatics, 2014, v. 33, n. 9, p. 597, doi. 10.1002/minf.201400058

By:

Saxena, Shalini;
Renuka, Janupally;
Yogeeswari, Perumal;
Sriram, Dharmarajan

Publication type:

Article