Works about DNA damage

Results: 5000

Cellular imbalance of specific RNA binding proteins associates with harmful R-loops.

Published in:

PLoS Genetics, 2025, v. 21, n. 7, p. 1, doi. 10.1371/journal.pgen.1011491

By:

Mérida-Cerro, José Antonio;
Chevreux, Guillaume;
Palancade, Benoit;
Rondón, Ana G.;
Aguilera, Andrés

Publication type:

Article

The anticancer potential of Origanum onites L. in gastric cancer through epigenetic alterations.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04942-7

By:

Sogutlu, Fatma;
Pekerbas, Mert;
Boztas, Gulsum;
Bayram, Emine;
Pariltay, Erhan;
Cogulu, Ozgur;
Biray Avci, Cigir

Publication type:

Article

PSMA5 as a modulator of glioblastoma senescence and prognosis.

Published in:

BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-025-14441-0

By:

Yao, Jiahao;
Zhang, Hongyu;
Gu, Qiang;
Sun, Xiaoyang;
Li, Lang;
Wang, Xuefeng

Publication type:

Article

Evolutionary Insights into the Length Variation of DNA Damage Response Proteins Across Eukaryotes Open Access.

Published in:

Genome Biology & Evolution, 2025, v. 17, n. 6, p. 1, doi. 10.1093/gbe/evaf089

By:

Wiredu-Boakye, Dominic;
Higgins, Laurence;
Gahura, Ondřej;
Butenko, Anzhelika;
Leonard, Guy;
Freeman, Mark A;
Kristmundsson, Árni;
Moore, Karen;
Harrison, Jamie W;
Donald, Shani Mac;
Yurchenko, Vyacheslav;
Williams, Bryony A P;
Chahwan, Richard

Publication type:

Article

Optimizing Sunscreen Safety: The Impact of TiO 2 Particle Size on Toxicity and Biocompatibility.

Published in:

Nanomaterials (2079-4991), 2025, v. 15, n. 12, p. 951, doi. 10.3390/nano15120951

By:

Maddaleno, Adriana S.;
Casellas, Clàudia;
Teixidó, Elisabet;
Guardia-Escote, Laia;
Vinardell, Maria Pilar;
Mitjans, Montserrat

Publication type:

Article

Effect of Butein, a Plant Polyphenol, on Apoptosis and Necroptosis of Prostate Cancer Cells in 2D and 3D Cultures.

Published in:

Life (2075-1729), 2025, v. 15, n. 6, p. 836, doi. 10.3390/life15060836

By:

Lee, Yeji;
Lee, Changyeol;
Lee, Sang-Han;
Lee, Yoon-Jin

Publication type:

Article

Mechanistic Insights and Anti-cancer Activity of 2H-benzo[b][1,4]oxazin-3(4H)-one Linked 1,2,3-Triazoles in Human Cancer Cells.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1565657

By:

Liu, Qingying;
Hou, Xixi;
Tian, Mingyue;
He, Baoyu;
Guo, Jingjing;
Guo, Yajie;
Yang, Jianxue

Publication type:

Article

Onvansertib-Based Second-Line Therapies in Combination with Gemcitabine and Carboplatin in Patient-Derived Platinum-Resistant Ovarian Carcinomas.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5708, doi. 10.3390/ijms26125708

By:

Guffanti, Federica;
Mengoli, Ilaria;
Ricci, Francesca;
Perotti, Ludovica;
Capellini, Elena;
Sala, Laura;
Canesi, Simone;
Wu, Chu-Chiao;
Fruscio, Robert;
Ridinger, Maya;
Damia, Giovanna;
Chiappa, Michela

Publication type:

Article

In This Issue.

Published in:: Arthritis & Rheumatology, 2025, v. 77, n. 7, p. 1, doi. 10.1002/art.43281
Publication type:: Article

Induction of Type I Interferon–Dependent Activation and Migration of Inflammatory Dendritic Cells to Local Lymph Nodes by UV Light Exposure.

Published in:

Arthritis & Rheumatology, 2025, v. 77, n. 7, p. 867, doi. 10.1002/art.43108

By:

Sun, Xizhang;
Chao, Jaime L.;
Gerner, Michael;
Elkon, Keith B.

Publication type:

Article

An Immunosenescent CD8+ T Cell Subset in Patients with Axial Spondyloarthritis and Psoriatic Arthritis Links Spontaneous Motility to Telomere Shortening and Dysfunction.

Published in:

Arthritis & Rheumatology, 2025, v. 77, n. 7, p. 854, doi. 10.1002/art.43109

By:

Paldino, Giorgia;
Tedeschi, Valentina;
Proganò, Valentina;
Salvati, Erica;
Licursi, Valerio;
Vertecchi, Eleonora;
Bivolaru, Alexandru L.;
Molteni, Emanuele;
Scrivo, Rossana;
Congia, Mattia;
Cauli, Alberto;
Caccavale, Rosalba;
Paroli, Marino;
Kunkl, Martina;
Tuosto, Loretta;
Sorrentino, Rosa;
Fiorillo, Maria Teresa

Publication type:

Article

Early dynamics of Toxoplasma gondii infection in sheep inoculated at mid-gestation with archetypal type II oocysts.

Published in:

Veterinary Research, 2025, v. 56, n. 1, p. 1, doi. 10.1186/s13567-025-01557-1

By:

Sánchez-Sánchez, Roberto;
Horcajo, Pilar;
Fernández, Miguel;
Arranz-Solís, David;
Velasco-Jiménez, Natalia;
Re, Michela;
Gutiérrez-Expósito, Daniel;
Valdivia, Guillermo;
Alonso-Diez, Angela;
Benavides, Julio;
Ortega-Mora, Luis Miguel

Publication type:

Article

The Role of Genetic Variation in Modulating the Effects of Blended Fruits and Vegetables Versus Fruit- and Vegetable-Coated Food Products on Antioxidant Capacity, DNA Protection, and Vascular Health: A Randomized Controlled Trial.

Published in:

Nutrients, 2025, v. 17, n. 12, p. 2036, doi. 10.3390/nu17122036

By:

DeBenedictis, Julia N.;
Xu, Na;
de Kok, Theo M.;
van Breda, Simone G.

Publication type:

Article

Recent Physical Activity in Relation to DNA Damage and Repair Using the Comet Assay.

Published in:

Journal of Physical Activity & Health, 2014, v. 11, n. 4, p. 770, doi. 10.1123/jpah.2012-0278

By:

Cash, Stephanie Whisnant;
Beresford, Shirley A. A.;
Vaughan, Thomas L.;
Heagerty, Patrick J.;
Bernstein, Leslie;
White, Emily;
Neuhouser, Marian L.

Publication type:

Article

The BER necessities: the repair of DNA damage in human-adapted bacterial pathogens.

Published in:

Nature Reviews Microbiology, 2015, v. 13, n. 2, p. 83, doi. 10.1038/nrmicro3391

By:

van der Veen, Stijn;
Tang, Christoph M.

Publication type:

Article

Viral infection: Manipulation of DNA repair pathways.

Published in:

Nature Reviews Microbiology, 2014, v. 12, n. 8, p. 530, doi. 10.1038/nrmicro3320

By:

Nunes-Alves, Cláudio

Publication type:

Article

Bacterial physiology: Caulobacter chooses to self-destruct.

Published in:

Nature Reviews Microbiology, 2012, v. 10, n. 12, p. 802, doi. 10.1038/nrmicro2913

By:

Kåhrström, Christina Tobin

Publication type:

Article

Evasion of innate immunity by Mycobacterium tuberculosis: is death an exit strategy?

Published in:

Nature Reviews Microbiology, 2010, v. 8, n. 9, p. 668, doi. 10.1038/nrmicro2387

By:

Behar, Samuel M.;
Divangahi, Maziar;
Remold, Heinz G.

Publication type:

Article

No SOS Needed: A Second Bacterial Checkpoint System Stops Cell Division.

Published in:

2014

By:

Robinson, Richard

Publication type:

Letter to the Editor

A DNA Damage-Induced, SOS-Independent Checkpoint Regulates Cell Division in Caulobacter crescentus.

Published in:

PLoS Biology, 2014, v. 12, n. 10, p. 1, doi. 10.1371/journal.pbio.1001977

By:

Modell, Joshua W.;
Kambara, Tracy K.;
Perchuk, Barrett S.;
Laub, Michael T.

Publication type:

Article

In TFIIH, XPD Helicase Is Exclusively Devoted to DNA Repair.

Published in:

PLoS Biology, 2014, v. 12, n. 9, p. 1, doi. 10.1371/journal.pbio.1001954

By:

Kuper, Jochen;
Braun, Cathy;
Elias, Agnes;
Michels, Gudrun;
Sauer, Florian;
Schmitt, Dominik R.;
Poterszman, Arnaud;
Egly, Jean-Marc;
Kisker, Caroline

Publication type:

Article

Bulge, Bubble, and Y: How an RNA Exonuclease Repairs DNA, in Detail.

Published in:

PLoS Biology, 2014, v. 12, n. 3, p. 1, doi. 10.1371/journal.pbio.1001804

By:

Robinson, Richard

Publication type:

Article

Structural Insights Into DNA Repair by RNase T—An Exonuclease Processing 3′ End of Structured DNA in Repair Pathways.

Published in:

PLoS Biology, 2014, v. 12, n. 3, p. 1, doi. 10.1371/journal.pbio.1001803

By:

Hsiao, Yu-Yuan;
Fang, Woei-Horng;
Lee, Chia-Chia;
Chen, Yi-Ping;
Yuan, Hanna S.

Publication type:

Article

Def1 Promotes the Degradation of Pol3 for Polymerase Exchange to Occur During DNA-Damage–Induced Mutagenesis in Saccharomyces cerevisiae.

Published in:

PLoS Biology, 2014, v. 12, n. 1, p. 1, doi. 10.1371/journal.pbio.1001771

By:

Daraba, Andreea;
Gali, Vamsi K.;
Halmai, Miklós;
Haracska, Lajos;
Unk, Ildiko

Publication type:

Article

Regulation of Nucleotide Excision Repair by UV-DDB: Prioritization of Damage Recognition to Internucleosomal DNA.

Published in:

PLoS Biology, 2011, v. 9, n. 10, p. 1, doi. 10.1371/journal.pbio.1001183

By:

Fei, Jia;
Kaczmarek, Nina;
Luch, Andreas;
Glas, Andreas;
Carell, Thomas;
Naegeli, Hanspeter

Publication type:

Article

The BRCT Domain of PARP-1 Is Required for Immunoglobulin Gene Conversion.

Published in:

PLoS Biology, 2010, v. 8, n. 7, p. 1, doi. 10.1371/journal.pbio.1000428

By:

Paddock, Marcia N.;
Buelow, Ben D.;
Takeda, Shunichi;
Scharenberg, Andrew M.

Publication type:

Article

Fumarase: A Mitochondrial Metabolic Enzyme and a Cytosolic/Nuclear Component of the DNA Damage Response.

Published in:

PLoS Biology, 2010, v. 8, n. 3, p. 1, doi. 10.1371/journal.pbio.1000328

By:

Yogev, Ohad;
Yogev, Orli;
Singer, Esti;
Shaulian, Eitan;
Goldberg, Michal;
Fox, Thomas D.;
Pines, Ophry

Publication type:

Article

Ciprofloxacin Causes Persister Formation by Inducing the TisB toxin in Escherichia coli.

Published in:

PLoS Biology, 2010, v. 8, n. 2, p. 1, doi. 10.1371/journal.pbio.1000317

By:

Dörr, Tobias;
Vulić, Marin;
Lewis, Kim

Publication type:

Article

A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G2/M DNA Damage Checkpoint.

Published in:

PLoS Biology, 2010, v. 8, n. 1, p. 1, doi. 10.1371/journal.pbio.1000287

By:

van Vugt, Marcel A. T. M.;
Gardino, Alexandra K.;
Linding, Rune;
Ostheimer, Gerard J.;
Reinhardt, H. Christian;
Shao-En Ong;
Tan, Chris S.;
Hua Miao;
Keezer, Susan M.;
Jeijin Li;
Pawson, Tony;
Lewis, Timothy A.;
Carr, Steven A.;
Smerdon, Stephen J.;
Brummelkamp, Thijn R.;
Yaffe, Michael B.

Publication type:

Article

CDC5 Inhibits the Hyperphosphorylation of the Checkpoint Kinase Rad53, Leading to Checkpoint Adaptation.

Published in:

PLoS Biology, 2010, v. 8, n. 1, p. 1, doi. 10.1371/journal.pbio.1000286

By:

Vidanes, Genevieve M.;
Sweeney, Frédéric D.;
Galicia, Sarah;
Cheung, Stephanie;
Doyle, John P.;
Durocher, Daniel;
Toczyski, David P.

Publication type:

Article

Crystal Structure of the FeS ClusterContaining Nucleotide Excision Repair Helicase XPD.

Published in:

PLoS Biology, 2008, v. 6, n. 6, p. e149, doi. 10.1371/journal.pbio.0060149

By:

Wolski, Stefanie C.;
Kuper, Jochen;
Hänzelmann, Petra;
Truglio, James J.;
Croteau, Deborah L.;
Van Houten, Bennett;
Kisker, Caroline

Publication type:

Article

DNA Damage--Induced Bcl-xL Deamidation Is Mediated by NHE-1 Antiport Regulated Intracellular pH.

Published in:

PLoS Biology, 2007, v. 5, n. 1, p. 39, doi. 10.1371/journal.pbio.0050001

By:

Rui Zhao;
Oxley, David;
Smith, Trevor S.;
Follows, George A.;
Green, Anthony R.;
Alexander, Denis R.

Publication type:

Article

Impaired Genome Maintenance Suppresses the Growth Hormone--Insulin-Like Growth Factor 1 Axis in Mice with Cockayne Syndrome.

Published in:

PLoS Biology, 2007, v. 5, n. 1, p. 23, doi. 10.1371/journal.pbio.0050002

By:

van der Pluijm, Ingrid;
Garinis, George A.;
Brandt, Renata M. C.;
Gorgels, Theo G. M. F.;
Wijnhoven, Susan W.;
Diderich, Karin E. M.;
de Wit, Jan;
Mitchell, James R.;
van Oostrom, Conny;
Beems, Rudolf;
Niedernhofer, Laura J.;
Velasco, Susana;
Friedberg, Errol C.;
Tanaka, Kiyoji;
van Steeg, Harry;
Hoeijmakers, Jan H. J.;
van der Horst, Gijsbertus T. J.

Publication type:

Article

Manipulating Cellular pH Suggests Novel Anticancer Therapy.

Published in:

PLoS Biology, 2007, v. 5, n. 1, p. 1, doi. 10.1371/journal.pbio.0050010

By:

Gross, Liza

Publication type:

Article

Structural Insights into the Regulation of a Key Tumor Suppressor.

Published in:

PLoS Biology, 2006, v. 4, n. 2, p. e40, doi. 10.1371/journal.pbio.0040040

By:

Gross, Liza

Publication type:

Article

Stepwise Translocation of Dpo4 Polymerase during Error-Free Bypass of an oxoG Lesion.

Published in:

PLoS Biology, 2006, v. 4, n. 1, p. 1, doi. 10.1371/journal.pbio.0040011

By:

Rechkoblit, Olga;
Malinina, Lucy;
Cheng, Yuan;
Kuryavyi, Vitaly;
Broyde, Suse;
Geacintov, Nicholas E;
Patel, Dinshaw J

Publication type:

Article

After 30 Years of Study, the Bacterial SOS Response Still Surprises Us.

Published in:

PLoS Biology, 2005, v. 3, n. 7, p. 1, doi. 10.1371/journal.pbio.0030255

By:

Michel, Bénédicte

Publication type:

Article

After 30 Years of Study, the Bacterial SOS Response Still Surprises Us.

Published in:

PLoS Biology, 2005, v. 3, n. 7, p. 1174, doi. 10.1371/journal.pbio.0030255

By:

Michel, Bénédicte

Publication type:

Article

Three New Phases of Repairing DNA Damage in E. coli.

Published in:

PLoS Biology, 2005, v. 3, n. 7, p. 1152, doi. 10.1371/journal.pbio.0030239

By:

Friedman, N.;
Vardi, S.;
Ronen, M.;
Alon, U.;
Stavans, J.

Publication type:

Article

Precise Temporal Modulation in the Response of the SOS DNA Repair Network in Individual Bacteria.

Published in:

PLoS Biology, 2005, v. 3, n. 6, p. 1, doi. 10.1371/journal.pbio.0030238

By:

Friedman, Nir;
Vardi, Shuki;
Ronen, Michal;
Alon, Uri;
Stavans, Joel

Publication type:

Article

Inhibition of Mutation and Combating the Evolution of Antibiotic Resistance.

Published in:

PLoS Biology, 2005, v. 3, n. 5, p. 1, doi. 10.1371/journal.pbio.0030176

By:

Cirz, Ryan T;
Chin, Jodie K;
Andes, David R;
de Crécy-Lagard, Valérie;
Craig, William A;
Romesberg, Floyd E

Publication type:

Article

Preserving Genome Integrity: The DdrA Protein of Deinococcus radiodurans R1.

Published in:

PLoS Biology, 2004, v. 2, n. 10, p. 1629, doi. 10.1371/journal.pbio.0020304

By:

Harris, Dennis R.;
Tanaka, Masashi;
Saveliev, Sergei V.;
Jolivet, Edmond;
Earl, Ashlee M.;
Cox, Michael M.;
Battista, John R.

Publication type:

Article

Mre11 Assembles Linear DNA Fragments into DNA Damage Signaling Complexes.

Published in:

PLoS Biology, 2004, v. 2, n. 5, p. 1, doi. 10.1371/journal.pbio.0020110

By:

Costanzo, Vincenzo;
Paull, Tanya;
Gottesman, Max;
Gautier, Jean

Publication type:

Article

Synopses of Research Articles.

Published in:: PLoS Biology, 2004, v. 2, n. 5, p. 551
Publication type:: Article

Role of Saccharomyces Single-Stranded DNA-Binding Protein RPA in the Strand Invasion Step of Double-Strand Break Repair.

Published in:

PLoS Biology, 2004, v. 2, n. 1, p. 0104, doi. 10.1371/journal.pbio.0020021

By:

Xuan Wang, Jeremy E.;
Haber, James E.;
West, Steven

Publication type:

Article

A DNA-Binding Protein Helps Repair Breaks in DNA Double Helix.

Published in:: PLoS Biology, 2004, v. 2, n. 1, p. 6, doi. 10.1371/journal.pbio.0020074
Publication type:: Article

Biochemical Characterization of DNA Damage Checkpoint Complexes: Clamp Loader and Clamp Complexes with Specificity for 5′ Recessed DNA.

Published in:

PLoS Biology, 2003, v. 1, n. 11, p. 1, doi. 10.1371/journal.pbio.0000033

By:

Ellison, Viola;
Stillman, Bruce

Publication type:

Article

Diagnóstico clínico y de laboratorio de la anemia de Fanconi.

Published in:

Acta Pediatrica de Mexico, 2012, v. 33, n. 1, p. 38

By:

García-de Teresa, Benilde;
del Castillo, Victoria;
Molina, M en C. Bertha;
Frías, Dra. Sara

Publication type:

Article

Synergistic cytotoxicity of the poly ( ADP-ribose) polymerase inhibitor ABT-888 and temozolomide in dual-drug targeted magnetic nanoparticles.

Published in:

Liver International, 2015, v. 35, n. 4, p. 1430, doi. 10.1111/liv.12586

By:

Muñoz‐Gámez, José A;
López Viota, Julián;
Barrientos, Andrés;
Carazo, Ángel;
Sanjuán‐Nuñez, Laura;
Quiles‐Perez, Rosa;
Muñoz‐de‐Rueda, Paloma;
Delgado, Ángel;
Ruiz‐Extremera, Ángeles;
Salmerón, Javier

Publication type:

Article

Aflatoxin genotoxicity is associated with a defective DNA damage response bypassing p53 activation.

Published in:

Liver International, 2011, v. 31, n. 4, p. 561, doi. 10.1111/j.1478-3231.2011.02474.x

By:

Gursoy-Yuzugullu, Ozge;
Yuzugullu, Haluk;
Yilmaz, Mustafa;
Ozturk, Mehmet

Publication type:

Article