Works about COMPLEMENT inhibition

Results: 757

Advances in Complement Inhibitory Strategies for the Treatment of Glomerular Disease: A Rapidly Evolving Field.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 12, p. 4204, doi. 10.3390/jcm14124204

By:

Conversano, Ester;
Vivarelli, Marina

Publication type:

Article

Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2.

Published in:

PLoS Biology, 2009, v. 7, n. 2, p. e1000038, doi. 10.1371/journal.pbio.1000038

By:

Feldman, Morris E.;
Apsel, Beth;
Uotila, Aino;
Loewith, Robbie;
Knight, Zachary A.;
Ruggero, Davide;
Shokat, Kevan M.

Publication type:

Article

Inhalation of Stachybotrys chartarum Evokes Pulmonary Arterial Remodeling in Mice, Attenuated by Rho-Kinase Inhibitor.

Published in:

Mycopathologia, 2011, v. 172, n. 1, p. 5, doi. 10.1007/s11046-011-9400-3

By:

Nagayoshi, Masaru;
Tada, Yuji;
West, James;
Ochiai, Eri;
Watanabe, Akira;
Toyotome, Takahito;
Tanabe, Nobuhiro;
Takiguchi, Yuichi;
Shigeta, Ayako;
Yasuda, Tadashi;
Shibuya, Kazutoshi;
Kamei, Katsuhiko;
Tatsumi, Koichiro

Publication type:

Article

Effect of a probiotic bacterium Bacillus circulans PB7 in the formulated diets: on growth, nutritional quality and immunity of Catla catla (Ham.).

Published in:

Fish Physiology & Biochemistry, 2009, v. 35, n. 3, p. 467, doi. 10.1007/s10695-008-9272-8

By:

Bandyopadhyay, Partha;
Das Mohapatra, Pradeep K.

Publication type:

Article

Increased complement activation 3 to 6 h after trauma is a predictor of prolonged mechanical ventilation and multiple organ dysfunction syndrome: a prospective observational study.

Published in:

Molecular Medicine, 2021, v. 27, n. 1, p. 1, doi. 10.1186/s10020-021-00286-3

By:

Rognes, Ingrid Nygren;
Pischke, Søren Erik;
Ottestad, William;
Røislien, Jo;
Berg, Jens Petter;
Johnson, Christina;
Eken, Torsten;
Mollnes, Tom Eirik

Publication type:

Article

A narrative review of potential drug treatments for nephritis in children with IgA vasculitis (HSP).

Published in:

Clinical Rheumatology, 2023, v. 42, n. 12, p. 3189, doi. 10.1007/s10067-023-06781-8

By:

Williams, Chloe E C;
Lamond, Megan;
Marro, Julien;
Chetwynd, Andrew J;
Oni, Louise

Publication type:

Article

Immune evasion by a staphylococcal complement inhibitor that acts on C3 convertases.

Published in:

Nature Immunology, 2005, v. 6, n. 9, p. 920, doi. 10.1038/ni1235

By:

Rooijakkers, Suzan H. M.;
Ruyken, Maartje;
Roos, Anja;
Daha, Mohamed R.;
Presanis, Julia S.;
Sim, Robert B.;
van Wamel, Willem J. B.;
van Kessel, Kok P. M.;
van Strijp, Jos A. G.

Publication type:

Article

Photodynamic inactivation of recombinant bioluminescent Escherichia coli by cationic porphyrins under artificial and solar irradiation.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2008, v. 35, n. 11, p. 1447, doi. 10.1007/s10295-008-0446-2

By:

Alves, Eliana;
Carvalho, Carla M. B.;
Tomé, João P. C.;
Faustino, Maria A. F.;
Neves, Maria G. P. M. S.;
Tomé, Augusto C.;
Cavaleiro, José A. S.;
Cunha, Ângela;
Mendo, Sónia;
Almeida, Adelaide

Publication type:

Article

Complement in Antibody-Mediated Rejection of the Kidney Graft: From Pathophysiology to Clinical Practice.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 8, p. 2810, doi. 10.3390/jcm14082810

By:

Sorohan, Bogdan Marian;
Tacu, Dorina;
Gîngu, Constantin;
Guler-Margaritis, Silviu;
Obrișcă, Bogdan;
Tănăsescu, Maria-Daniela;
Ismail, Gener;
Baston, Cătălin

Publication type:

Article

C4d Is an Independent Predictor of the Kidney Failure in Primary IgA Nephropathy.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 17, p. 5338, doi. 10.3390/jcm13175338

By:

Zagorec, Nikola;
Horvatić, Ivica;
Kasumović, Dino;
Osmani, Besa;
Sović, Slavica;
Nikić, Jagoda;
Horaček, Matija;
Šenjug, Petar;
Galešić, Krešimir;
Galešić Ljubanović, Danica

Publication type:

Article

Complement Inhibitors for Advanced Dry Age-Related Macular Degeneration (Geographic Atrophy): Some Light at the End of the Tunnel?

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 15, p. 5131, doi. 10.3390/jcm12155131

By:

Cruz-Pimentel, Miguel;
Wu, Lihteh

Publication type:

Article

Current Therapies in Kidney Transplant Rejection.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 15, p. 4927, doi. 10.3390/jcm12154927

By:

Alasfar, Sami;
Kodali, Lavanya;
Schinstock, Carrie A.

Publication type:

Article

Bruch's Membrane: A Key Consideration with Complement-Based Therapies for Age-Related Macular Degeneration.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 8, p. 2870, doi. 10.3390/jcm12082870

By:

Hammadi, Sarah;
Tzoumas, Nikolaos;
Ferrara, Mariantonia;
Meschede, Ingrid Porpino;
Lo, Katharina;
Harris, Claire;
Lako, Majlinda;
Steel, David H.

Publication type:

Article

New Targeted Agents in Myasthenia Gravis and Future Therapeutic Strategies.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 21, p. 6394, doi. 10.3390/jcm11216394

By:

Sánchez-Tejerina, Daniel;
Sotoca, Javier;
Llaurado, Arnau;
López-Diego, Veronica;
Juntas-Morales, Raul;
Salvado, Maria

Publication type:

Article

Postsurgical Thrombotic Microangiopathy and Deregulated Complement.

Published in:

2022

By:

van Herpt, Thijs T. W.;
Timmermans, Sjoerd A. M. E. G.;
van Mook, Walther N. K. A.;
van Bussel, Bas C. T.;
van der Horst, Iwan C. C.;
Maessen, Jos G.;
Natour, Ehsan;
van Paassen, Pieter;
Heuts, Samuel

Publication type:

Case Study

Systemic Complement Activation Profiles in Nonexudative Age-Related Macular Degeneration: A Meta-Analysis.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 9, p. 2371, doi. 10.3390/jcm11092371

By:

Lin, Jonathan B.;
Serghiou, Stylianos;
Miller, Joan W.;
Vavvas, Demetrios G.

Publication type:

Article

The Complement System, T Cell Response, and Cytokine Shift in Normotensive versus Pre-Eclamptic and Lupus Pregnancy.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 24, p. 5722, doi. 10.3390/jcm10245722

By:

Ancuța, Eugen;
Zamfir, Radu;
Martinescu, Gabriel;
Crauciuc, Dragoș Valentin;
Ancuța, Codrina

Publication type:

Article

The Contribution of Complement to the Pathogenesis of IgA Nephropathy: Are Complement-Targeted Therapies Moving from Rare Disorders to More Common Diseases?

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 20, p. 4715, doi. 10.3390/jcm10204715

By:

Poppelaars, Felix;
Faria, Bernardo;
Schwaeble, Wilhelm;
Daha, Mohamed R.

Publication type:

Article

The Syndromes of Thrombotic Microangiopathy: A Critical Appraisal on Complement Dysregulation.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 14, p. 3034, doi. 10.3390/jcm10143034

By:

Timmermans, Sjoerd A. M. E. G.;
van Paassen, Pieter

Publication type:

Article

Complement Inhibition for Geographic Atrophy: A Tempting Target with Mixed Results.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 13, p. 2890, doi. 10.3390/jcm10132890

By:

Lin, Jonathan B.;
Halawa, Omar A.;
Miller, Joan W.;
Vavvas, Demetrios G.

Publication type:

Article

A Review of Completed and Ongoing Complement Inhibitor Trials for Geographic Atrophy Secondary to Age-Related Macular Degeneration.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 12, p. 2580, doi. 10.3390/jcm10122580

By:

Halawa, Omar A.;
Lin, Jonathan B.;
Miller, Joan W.;
Vavvas, Demetrios G.

Publication type:

Article

Difficult Cases of Paroxysmal Nocturnal Hemoglobinuria: Diagnosis and Therapeutic Novelties.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 5, p. 948, doi. 10.3390/jcm10050948

By:

Fattizzo, Bruno;
Serpenti, Fabio;
Giannotta, Juri Alessandro;
Barcellini, Wilma;
Ramos, Fernando

Publication type:

Article

New Insights in Autoimmune Hemolytic Anemia: From Pathogenesis to Therapy.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 12, p. 3859, doi. 10.3390/jcm9123859

By:

Barcellini, Wilma;
Zaninoni, Anna;
Giannotta, Juri Alessandro;
Fattizzo, Bruno

Publication type:

Article

Complement Inhibition Therapy and Dialytic Strategies in Paroxysmal Nocturnal Hemoglobinuria: The Nephrologist's Opinion.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 5, p. 1261, doi. 10.3390/jcm9051261

By:

Gembillo, Guido;
Siligato, Rossella;
Cernaro, Valeria;
Santoro, Domenico

Publication type:

Article

Emerging roles and new functions of CD46.

Published in:

Springer Seminars in Immunopathology, 2005, v. 27, n. 3, p. 345, doi. 10.1007/s00281-005-0002-3

By:

Liszewski, M. Kathryn;
Kemper, Claudia;
Price, Jeffrey D.;
Atkinson, John P.

Publication type:

Article

Complement C2 receptor inhibitor trispanning: from man to schistosome.

Published in:

Springer Seminars in Immunopathology, 2005, v. 27, n. 3, p. 320, doi. 10.1007/s00281-005-0009-9

By:

Inal, Jameel

Publication type:

Article

Hypertensive Emergency and Atypical Hemolytic Uremic Syndrome Associated with Cocaine Use: A Diagnostic and Therapeutic Challenge.

Published in:

2025

By:

Jiménez Mayor, Elena;
De La Flor, José C.;
Rocha Rodrigues, André;
Rodríguez Tudero, Celia;
Zamora González-Mariño, Rocío;
Apaza, Jacqueline;
Moral Berrio, Esperanza;
Deira Lorenzo, Javier

Publication type:

Case Study

Molecular mechanism of complement inhibition by the trypanosome receptor ISG65.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.88960

By:

Cook, Alexander D.;
Carrington, Mark;
Higgins, Matthew K.

Publication type:

Article

Eculizumab is efficacious and safe in pediatric patients with various forms of hemolytic uremic syndrome: a retrospective clinical experience of a tertiary center.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1535407

By:

Lax, Naama;
Davidovits, Miriam;
Chodick, Gabriel;
Bernfeld, Yael;
Peled, Orit

Publication type:

Article

Eculizumab is efficacious and safe in pediatric patients with various forms of hemolytic uremic syndrome: a retrospective clinical experience of a tertiary center.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1535407

By:

Lax, Naama;
Davidovits, Miriam;
Chodick, Gabriel;
Bernfeld, Yael;
Peled, Orit

Publication type:

Article

Efficacy and safety of complement inhibitors in patients with geographic atrophy associated with age-related macular degeneration: a network meta-analysis of randomized controlled trials.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1410172

By:

Wang, Huan;
Zheng, Jiaqi;
Zhang, Qing;
Tian, Zhongping;
Sun, Yuhang;
Zhu, Tianyi;
Bi, Yanlong;
Zhang, Li

Publication type:

Article

Protective role of complement factor H against the development of preeclampsia.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1351898

By:

Yasmin, Hadida;
Agostinis, Chiara;
Toffoli, Miriam;
Roy, Tamali;
Pegoraro, Silvia;
Balduit, Andrea;
Zito, Gabriella;
Di Simone, Nicoletta;
Ricci, Giuseppe;
Madan, Taruna;
Kishore, Uday;
Bulla, Roberta

Publication type:

Article

Tertiary lymphoid structures as local perpetuators of organspecific immune injury: implication for lupus nephritis.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1204777

By:

Meiying Wang;
Rajkumar, Snehin;
Yupeng Lai;
Xingjiao Liu;
Jing He;
Tatsuya Ishikawa;
Nallapothula, Dhiraj;
Singh, Ram Raj

Publication type:

Article

Non-capsulated Neisseria meningitidis sepsis in a paroxysmal nocturnal hemoglobinuria patient treated with ravulizumab: case report and review of the literature.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1269325

By:

Galli, Nicole;
Pettine, Loredana;
Panigada, Mauro;
Daprai, Laura;
Suriano, Grazia;
Grancini, Anna;
Barcellini, Wilma;
Fattizzo, Bruno

Publication type:

Article

Heterogenous lung inflammation CT patterns distinguish pneumonia and immune checkpoint inhibitor pneumonitis and complement blood biomarkers in acute myeloid leukemia: proof of concept.

Published in:

Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1249511

By:

Aminu, Muhammad;
Daver, Naval;
Godoy, Myrna C. B.;
Shroff, Girish;
Wu, Carol;
Torre-Sada, Luis F.;
Goizueta, Alberto;
Shannon, Vickie R.;
Faiz, Saadia A.;
Altan, Mehmet;
Garcia-Manero, Guillermo;
Kantarjian, Hagop;
Ravandi-Kashani, Farhad;
Kadia, Tapan;
Konopleva, Marina;
DiNardo, Courtney;
Pierce, Sherry;
Aung Naing;
Kim, Sang T.;
Kontoyiannis, Dimitrios P.

Publication type:

Article

Corrigendum: Zilucoplan, a macrocyclic peptide inhibitor of human complement component 5, uses a dual mode of action to prevent terminal complement pathway activation.

Published in:: Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1282155
Publication type:: Article

Zilucoplan, a macrocyclic peptide inhibitor of human complement component 5, uses a dual mode of action to prevent terminal complement pathway activation.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1213920

By:

Guo-Qing Tang;
Yalan Tang;
Dhamnaskar, Ketki;
Hoarty, Michelle D.;
Vyasamneni, Rohit;
Vadysirisack, Douangsone D.;
Zhong Ma;
Nanqun Zhu;
Jian-Guo Wang;
Bu, Charlie;
Cong, Bestine;
Palmer, Elizabeth;
Duda, Petra W.;
Sayegh, Camil;
Ricardo, Alonso

Publication type:

Article

Severe autoimmune hemolytic anemia; epidemiology, clinical management, outcomes and knowledge gaps.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1228142

By:

Mulder, Femke V. M.;
Evers, Dorothea;
de Haas, Masja;
Cruijsen, Marjan J.;
Bernelot Moens, Sophie J.;
Barcellini, Wilma;
Fattizzo, Bruno;
Vos, Josephine M. I.

Publication type:

Article

Complement inhibition can decrease the haemostatic response in a microvascular bleeding model at multiple levels.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1226832

By:

Golomingi, Murielle;
Kohler, Jessie;
Lamers, Christina;
Pouw, Richard B.;
Ricklin, Daniel;
Dobó, József;
Gál, Péter;
Pál, Gábor;
Kiss, Bence;
Dopler, Arthur;
Schmidt, Christoph Q.;
Hardy, Elaissa Trybus;
Lam, Wilbur;
Schroeder, Verena

Publication type:

Article

Zilucoplan, a macrocyclic peptide inhibitor of human complement component 5, uses a dual mode of action to prevent terminal complement pathway activation.

Published in:

Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1213920

By:

Guo-Qing Tang;
Yalan Tang;
Dhamnaskar, Ketki;
Hoarty, Michelle D.;
Vyasamneni, Rohit;
Vadysirisack, Douangsone D.;
Zhong Ma;
Nanqun Zhu;
Jian-Guo Wang;
Bu, Charlie;
Cong, Bestine;
Palmer, Elizabeth;
Duda, Petra W.;
Sayegh, Camil;
Ricardo, Alonso

Publication type:

Article

Editorial: Expert opinions and perspectives in complement: 2022.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1248299

By:

Okrój, Marcin;
Merle, Nicolas S.;
Jinhua Lu

Publication type:

Article

In vaccinated individuals serum bactericidal activity against B meningococci is abrogated by C5 inhibition but not by inhibition of the alternative complement pathway.

Published in:

Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1180833

By:

Ispasanie, Emma;
Muri, Lukas;
Schmid, Marc;
Schubart, Anna;
Thorburn, Christine;
Zamurovic, Natasa;
Holbro, Thomas;
Kammüller, Michael;
Pluschke, Gerd

Publication type:

Article

Citrullination of C1-inhibitor as a mechanism of impaired complement regulation in rheumatoid arthritis.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1203506

By:

Martin, Myriam;
Nilsson, Sara C.;
Eikrem, David;
Fromell, Karin;
Scavenius, Carsten;
Vogt, Leonie M.;
Bielecka, Ewa;
Potempa, Jan;
Enghild, Jan J.;
Nilsson, Bo;
Ekdahl, Kristina N.;
Kapetanovic, Meliha C.;
Blom, Anna M.

Publication type:

Article

C4b-binding protein inhibits particulate- and crystalline-induced NLRP3 inflammasome activation.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1149822

By:

Bierschenk, Damien;
Papac-Milicevic, Nikolina;
Bresch, Ian P.;
Kovacic, Valentina;
Bettoni, Serena;
Dziedzic, Mateusz;
Wetsel, Rick A.;
Eschenburg, Susanne;
Binder, Christoph J.;
Blom, Anna M.;
King, Ben C.

Publication type:

Article

Efficient complement-mediated clearance of immunosuppressed T cells by macrophages.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1183180

By:

Gankema, Angela A. F.;
Furumaya, Charita;
Fernández-Hermira, Sara;
Hoogenboezem, Mark;
Matlung, Hanke L.;
van Bruggen, Robin;
Kuijpers, Taco W.

Publication type:

Article

Evaluating the comorbidities of age and cigarette smoking on stroke outcomes in the context of anti-complement mitigation strategies.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1161051

By:

Couch, Christine;
Alawieh, Ali M.;
Toutonji, Amer;
Atkinson, Carl;
Tomlinson, Stephen

Publication type:

Article

The choice of new treatments in autoimmune hemolytic anemia: how to pick from the basket?

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1180509

By:

Berentsen, Sigbjørn;
Fattizzo, Bruno;
Barcellini, Wilma

Publication type:

Article

The many faces of parasite calreticulin.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1101390

By:

Esperante, Diego;
Flisser, Ana;
Mendlovic, Fela

Publication type:

Article

Fusarium species detected in onychomycosis in Colombia.

Published in:

Mycoses, 2009, v. 52, n. 4, p. 350, doi. 10.1111/j.1439-0507.2008.01619.x

By:

Castro López, Natalia;
Casas, Clemencia;
Sopo, Leticia;
Rojas, Alejandro;
Del Portillo, Patricia;
Cepero de García, María Caridad;
Restrepo, Silvia

Publication type:

Article

Pegcetacoplan: A New Opportunity for Complement Inhibition in PNH.

Published in:

Journal of Blood Medicine, 2023, v. 14, p. 239, doi. 10.2147/JBM.S362220

By:

Weitz, Ilene Ceil

Publication type:

Article