Works matching DE "CLINICAL trials"

Results: 5000

Advancing equitable access to innovation in breast cancer.

Published in:

NPJ Breast Cancer, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41523-025-00768-1

By:

O'Reilly, Seamus;
Luis, Ines Vaz;
Adam, Virginie;
Razis, Evangelia D.;
Urruticoechea, Ander;
Arahmani, Amal;
Carrasco, Eva;
Chua, Boon H.;
Bliss, Judith;
Straehle, Carolyn;
Goulioti, Theodora;
Lindholm, Barbro;
Werustsky, Gustavo;
Brain, Etienne;
Bedard, Philippe L.;
Curigliano, Giuseppe;
Loi, Sherene;
Saji, Shigehira;
Cameron, David

Publication type:

Article

A generalizable and open-source algorithm for real-life monitoring of tremor in Parkinson's disease.

Published in:

NPJ Parkinson's Disease, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41531-025-01056-2

By:

Timmermans, Nienke A.;
Terranova, Roberta;
Soriano, Diogo C.;
Cagnan, Hayriye;
Raykov, Yordan P.;
Bucur, Ioan Gabriel;
Bloem, Bastiaan R.;
Helmich, Rick C.;
Evers, Luc J. W.

Publication type:

Article

Do Targeted Interventions Diminish Victimization? Testing the Short- and Longer-term Effectiveness of Condemning, Empathy-Raising, and Combined Approaches.

Published in:

Journal of Youth & Adolescence, 2025, v. 54, n. 7, p. 1659, doi. 10.1007/s10964-025-02173-0

By:

Laninga-Wijnen, Lydia;
Huisman, Mark;
Graf, Daniel;
Salmivalli, Christina

Publication type:

Article

Colchicine for secondary prevention of vascular events: a meta-analysis of trials Free.

Published in:

European Heart Journal, 2025, v. 46, n. 26, p. 2564, doi. 10.1093/eurheartj/ehaf210

By:

d'Entremont, Marc-André;
Poorthuis, Michiel H F;
Fiolet, Aernoud T L;
Amarenco, Pierre;
Boczar, Kevin Emery;
Buysschaert, Ian;
Chan, Noel C;
Cornel, Jan H;
Jannink, Jalina;
Jansen, Shirley;
Kedev, Sasko;
Keech, Anthony C;
Layland, Jamie;
Mewton, Nathan;
Montalescot, Gilles;
Pascual-Figal, Domingo A;
Rodriguez, Alfredo E;
Shah, Binita;
Teraa, Martin;
Zelm, Aimee van

Publication type:

Article

Definitions and standardized endpoints for the use of drug-coated balloon in coronary artery disease: consensus document of the Drug Coated Balloon Academic Research Consortium Open Access.

Published in:

European Heart Journal, 2025, v. 46, n. 26, p. 2498, doi. 10.1093/eurheartj/ehaf029

By:

Fezzi, Simone;
Scheller, Bruno;
Cortese, Bernardo;
Alfonso, Fernando;
Jeger, Raban;
Colombo, Antonio;
Joner, Michael;
Shin, Eun-Seok;
Kleber, Franz X;
Latib, Azeem;
Rissanen, Tuomas T;
Eccleshall, Simon;
Ribichini, Flavio;
Tao, Ling;
Koo, Bon-Kwon;
Chieffo, Alaide;
Ge, Junbo;
Granada, Juan F;
Stoll, Hans-Peter;
Spaulding, Christian

Publication type:

Article

Comparing the effects of physical activity and cognitive training on cognitive performance, physical fitness, and mental health in 9- to 10-year-old children: a randomized clinical trial.

Published in:

Frontiers in Psychology, 2025, p. 1, doi. 10.3389/fpsyg.2025.1555451

By:

Wang, Shanshan;
Liu, Jingwu

Publication type:

Article

Vaccine-induced responses to R21/Matrix-M – an analysis of samples from a phase 1b age de-escalation, dose-escalation trial.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1620366

By:

Bundi, Caroline;
Bellamy, Duncan;
Kibwana, Elizabeth;
Nyamako, Lydia;
Ogwang, Rodney;
Keter, Kelvias;
Kimani, Domtila;
Salman, Ahmed M.;
Provstgaard-Morys, Samuel;
Stockdale, Lisa;
Hill, Adrian V. S.;
Bejon, Philip;
Olotu, Ally;
Hamaluba, Mainga;
Ewer, Katie J.;
Kapulu, Melissa C.

Publication type:

Article

Unlocking the therapeutic potential of thymus-isolated regulatory T cells.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1612360

By:

Hu, Yueyuan;
Cruz, Hugo;
Santosh Nirmala, Samikshya;
Fuchs, Anke

Publication type:

Article

Impact of post-transplant cyclophosphamide with bendamustine on immune reconstitution in young patients undergoing T-cell replete haploidentical bone marrow transplantation: results from a phase Ia/Ib clinical trial.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1568862

By:

Baker, Forrest L.;
Stokes, Jessica;
Cracchiolo, Megan J.;
Davini, Dan;
Simpson, Richard J.;
Katsanis, Emmanuel

Publication type:

Article

P.158 Molecular characterization of RTOG-0539 risk groups in meningioma: insights into radiotherapy response and tumor biology.

Published in:

2025

By:

Yefet, L;
Landry, A;
Wang, J;
Liu, J;
Patil, V;
Gui, C;
Ellenbogen, Y;
Ajisebutu, A;
Nassiri, F;
Zadeh, G

Publication type:

Abstract

P.143 Eligibility criteria in glioma clinical trials: a systematic review and meta-analysis on selectivity, generalizability, and real-world applicability.

Published in:

2025

By:

Otaner, F;
Berger, MS;
Gerritsen, JK;
Young, JS

Publication type:

Abstract

P.107 Early and sustained response over time with zilucoplan in generalised Myasthenia Gravis: 120-week post hoc analysis of RAISE-XT.

Published in:

2025

By:

Blanchard, O;
Bresch, S;
Freimer, M;
Hewamadduma, C;
Leite, M;
Maniaol, A;
Utsugisawa, K;
Beau Lejdstrom, R;
Boroojerdi, B;
Grimson, F;
Savic, N;
Howard, JF

Publication type:

Abstract

P.100 A randomized, open-label study on the effect of Nipocalimab on vaccine responses in healthy participants.

Published in:

2025

By:

Cossu, M;
Bobadilla Mendez, C;
Jackson, A;
Myshkin, E;
Liu, G;
Lam, E;
Beier, U;
Weisel, K;
Scott, B;
Ait-Tihyaty, M;
Sattin, B;
Leu, J;
Gao, S;
Dimitrova, D

Publication type:

Abstract

P.099 Post-hoc evaluation of the clinical effects of nipocalimab, a neonatal fragment crystallizable blocker, over time in the Vivacity MG3 study.

Published in:

2025

By:

Nowak, R;
Ait-Tihyaty, M;
Turkoz, I;
Gandhi, K;
Rodriguez, R;
Pease, S;
Gingerich, S;
Katzberg, H

Publication type:

Abstract

P.096 Final pooled analysis of efficacy and safety of rozanolixizumab cycles in patients with generalised myasthenia gravis: MycarinG and open-label extension studies.

Published in:

2025

By:

Bril, V;
Antozzi, C;
Drużdż, A;
Grosskreutz, J;
Habib, AA;
Sacconi, S;
Utsugisawa, K;
Vissing, J;
Vu, T;
Grimson, F;
McDonough, B;
Pulido-Valdeolivas, I;
Tarancón, T

Publication type:

Abstract

P.094 A phase 1, multicenter, randomized, placebo-controlled, multiple ascending dose study to evaluate the safety and tolerability of AMX0114 in ALS (LUMINA).

Published in:

2025

By:

Paganoni, S;
Kett, L;
Bowser, R;
Kingston, L;
Mizerak, E;
Pesko, J;
Kerthi, J;
Timmons, J;
Genge, A;
Blackmon, S

Publication type:

Abstract

P.086 Randomized controlled trial evaluating virtual reality exposure therapy on epilepsy/seizure-specific interictal anxiety in people with epilepsy.

Published in:

2025

By:

Malik, K;
Inthiran, A;
Geitz, V;
Tchao, D;
Gray, HG;
Fung, SL;
Bui, E;
Gold, D;
Appel, L

Publication type:

Abstract

P.064 MOXIe clinical trial overview of omaveloxolone for patients with Friedreich ataxia.

Published in:

2025

By:

Escamilla, CO;
Lubkov, V;
Jaramillo, RF

Publication type:

Abstract

P.033 Long-term efficacy of Efgartigimod PH20 SC in patients with chronic inflammatory demyelinating polyneuropathy: interim results from the ADHERE+ study.

Published in:

2025

By:

Allen, JA;
Lin, J;
Stettner, M;
Guptill, J;
Gwathmey, K;
Istas, G;
De Roeck, A;
Kuwabara, S;
Lauria, G;
Querol, L;
Suresh, N;
Karam, C;
Skripuletz, T;
Rinaldi, S;
Echaniz-Laguna, A;
Van Hoorick, B;
Yamasaki, R;
Katzberg, H;
Van Doorn, PA;
Lewis, RA

Publication type:

Abstract

P.031 Consistency of objective sleep maintenance data in Chinese and North American/European subjects with insomnia in lemborexant phase 3 studies.

Published in:

2025

By:

Moline, M;
Cheng, JY;
Kumar, D;
Takase, T;
Yamakawa, N

Publication type:

Abstract

P.030 Impact of lemborexant on daytime sleepiness/alertness in participants with comorbid insomnia and mild obstructive sleep apnea.

Published in:

2025

By:

Moline, M;
Gardiner, F;
Kumar, D;
Cheng, JY;
Boulos, MI

Publication type:

Abstract

P.010 Interim efficacy and safety results from the ongoing phase 3 CHAMPION-NMOSD trial of ravulizumab in adults with AQP4-Ab+ NMOSD.

Published in:

2025

By:

Pittock, SJ;
Barnett, M;
Bennett, JL;
Berthele, A;
de Sèze, J;
Levy, M;
Nakashima, I;
Oreja-Guevara, C;
Palace, J;
Paul, F;
Pozzilli, C;
Allen, K;
Parks, B;
Kim, H;
Vorobeychik, G

Publication type:

Abstract

P.007 Tailoring a mindfulness intervention as a therapeutic intervention for mild cognitive impairment.

Published in:

2025

By:

Danielle, T;
Sherman, M;
Snozyk, T;
Nguyen, A;
Langis, E;
Nikolejsin, J;
Picken, KA;
Binder, L;
Henri-Bhargava, A

Publication type:

Abstract

F.3 fMRI-based deep brain stimulation programming: a blinded, crossover clinical trial.

Published in:

2025

By:

Santyr, B;
Boutet, A;
Germann, J;
Qiu, J;
Loh, A;
Alhashyan, I;
Chow, C;
Sarica, C;
Vetkas, A;
Yang, A;
Elias, G;
Lang, S;
Hodaie, M;
Kalia, S;
Fasano, A;
Ajala, A;
Lozano, A

Publication type:

Abstract

D.7 Efgartigimod impact on I-RODS daily activity assessment in chronic inflammatory demyelinating polyneuropathy: post hoc analysis of Registrational ADHERE Study.

Published in:

2025

By:

Allen, JA;
Lin, J;
Stettner, M;
Merkies, I;
Guptill, J;
Gwathmey, K;
Istas, G;
De Roeck, A;
Kuwabara, S;
Lauria, G;
Querol, L;
Suresh, N;
Karam, C;
Skripuletz, T;
Rinaldi, S;
Echaniz-Laguna, A;
Van Hoorick, B;
Yamasaki, R;
Katzberg, H;
Van Doorn, PA

Publication type:

Abstract

B.6 Location-specific hematoma volume tolerances for spontaneous intracerebral hemorrhage.

Published in:

2025

By:

Brissette, V;
Ouyang, M;
Yogendrakumar, V;
Ramsay, T;
Mallick, R;
Morotti, A;
Goldstein, JN;
Anderson, C;
Dowlatshahi, D

Publication type:

Abstract

GR.6 Deep brain stimulation of the nucleus accumbens for severe self-injurious behaviour in children: a phase I pilot trial.

Published in:

2025

By:

Mithani, K;
Gorodetsky, C;
Breitbart, S;
Yan, H;
Zhang, K;
Gouveia, FV;
Warsi, N;
Suresh, H;
Wong, SM;
Huber, J;
Kerr, EN;
Kulkarni, AV;
Taylor, MJ;
Hagopian, L;
Fasano, A;
Ibrahim, GM

Publication type:

Abstract

The Value and Importance of a Professional Ethical Code for Medicines Development: IFAPP International Ethics Framework.

Published in:

Pharmaceutical Medicine, 2025, v. 39, n. 4, p. 249, doi. 10.1007/s40290-024-00547-6

By:

Kerpel-Fronius, Sandor;
Becker, Alexander L.

Publication type:

Article

Treatment of infected wounds with cold atmospheric plasma: a case series.

Published in:

Journal of Wound Care, 2025, v. 34, n. 7, p. 506, doi. 10.12968/jowc.2025.0132

By:

Ricci, Elia;
Pittarello, Monica;
Ricci, Andrea;
Ascher, Stefanie;
Gebhardt, Lisa

Publication type:

Article

Non-inferiority randomised controlled trial of two contact layer dressings for the treatment of acute wounds (SLALOM).

Published in:

Journal of Wound Care, 2025, v. 34, n. 7, p. 496, doi. 10.12968/jowc.2024.0312

By:

Meaume, Sylvie;
Kerihuel, Jean-Charles;
Malatesta, Andres;
Roux, Flavien;
Trofimenko, Daria;
Abel, Martin

Publication type:

Article

Correction to: Comparison of Demographics: National Amyotrophic Lateral Sclerosis Registry and Clinical Trials Data.

Published in:

2025

By:

Han, Moon;
Raymond, Jaime;
Larson, Theodore C.;
Mehta, Paul;
Horton, D. Kevin

Publication type:

Correction Notice

Role of Gastrointestinal Tract (GUT) Health in Reducing Non-communicable Disease Risk.

Published in:

Journal of Comprehensive Health, 2025, v. 13, n. 1, p. 1, doi. 10.25259/JCH_29_2024

By:

Tripti, Tanu;
Ghosh, Joyeta

Publication type:

Article

COMPREHENSIVE ANALYSIS OF OCRELIZUMAB'S EFFICACY ACROSS DIFFERENT FORMS OF MULTIPLE SCLEROSIS: A MULTI-DIMENSIONAL APPROACH.

Published in:

Medical Science Pulse, 2024, v. 18, n. 4, p. 10, doi. 10.5604/01.3001.0054.8128

By:

GIL, KACPER;
DANIEK, JUSTYNA;
ŁACH, ALEKSANDRA;
CYTLAU, BARTŁOMIEJ;
SKORUPA, MARCIN

Publication type:

Article

Capillary Blood Self‐Sampling for Therapeutic Drug Monitoring: A Mixed‐Methods Usability Study of the True Dose<sup>®</sup> Kit.

Published in:

BioMed Research International, 2025, v. 2025, p. 1, doi. 10.1155/bmri/9973081

By:

Crafoord, Marie-Therése;
Hedayati, Elham;
Johnsson, Aina;
Banerjee, Baisakhi

Publication type:

Article

Word Learning in Children With Developmental Language Disorder: The Use of Retrieval Practice During Shared Book Reading.

Published in:

Journal of Speech, Language & Hearing Research, 2025, v. 68, n. 7, p. 3305, doi. 10.1044/2025_JSLHR-24-00809

By:

Souto, Sofia;
Leonard, Laurence B.;
Deevy, Patricia;
Christ, Sharon L.;
Karpicke, Jeffrey D.;
Schroeder, Mariel L.

Publication type:

Article

Novel melasma therapy using combined low fluence and microsecond pulse Q switched 1064 nm neodymium doped yttrium aluminium garnet laser.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10129-4

By:

Wu, Xianglei;
Cen, Qingqing;
Lin, Xiaoxi;
Shang, Ying;
Wang, Xue;
Zhang, Zhen

Publication type:

Article

Acupuncture for migraine: a literature review of neuroimaging studies.

Published in:

Frontiers in Neurology, 2025, p. 1, doi. 10.3389/fneur.2025.1601554

By:

Tong, Dan;
Yao, Rui;
Zhang, Xinyue;
Tao, Siyuan;
Chen, Nuo;
Wu, Wanxia;
Wu, Sai;
Zhou, Jun;
Ren, Yulan;
Liang, Fanrong;
Pan, Litao;
Li, Zhengjie

Publication type:

Article

Optimizing public-private partnerships to support clinical cancer research.

Published in:

JNCI: Journal of the National Cancer Institute, 2025, v. 117, n. 7, p. 1305, doi. 10.1093/jnci/djae279

By:

Herbst, Roy S;
Blumenthal, Gideon;
Khleif, Samir N;
Lippman, Scott M;
Meropol, Neal J;
Rosati, Kristen;
Shulman, Lawrence N;
Smith, Heind;
Wang, Meina;
Winn, Robert A;
Schilsky, Richard L

Publication type:

Article

Ketogenic therapy for schizophrenia: evidence, mechanisms, and clinical perspectives.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1603722

By:

Chaves, Cristiano;
Fabe, Jennifer;
Gomes, Fabiano A.;
McNeely, Heather;
Tusconi, Massimo;
Carta, Mauro Giovanni;
Dursun, Serdar M.;
Hallak, Jaime E. C.;
Brietzke, Elisa

Publication type:

Article

Neoadjuvant chemotherapy with or without metformin in early-stage or locally advanced (non-metastatic) triple negative breast cancer—an open-label phase 2 randomized controlled trial.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1561692

By:

Ramani, Vinod K.;
Basavalinga Sadashivaiah, Ajaikumar;
Naik, Radheshyam

Publication type:

Article

Safety Reporting in Trials on Atrial Fibrillation: An Observational Study of ClinicalTrials.gov Registry and Corresponding Publications.

Published in:

Journal of Cardiovascular Electrophysiology, 2025, v. 36, n. 6, p. 1377, doi. 10.1111/jce.16682

By:

Lišnić, Viktoria;
Šaler, Fran;
Viđak, Marin;
Marušić, Ana

Publication type:

Article

Is concurrent training effective in the symptomatology of menopause, depression, sexual function, and the aging perspective of women during menopause? A randomised clinical trial.

Published in:

Menopausal Review / Przegląd Menopauzalny, 2025, v. 24, n. 1, p. 33, doi. 10.5114/pm.2025.150142

By:

Medeiros Scarpel, Cibele;
Fausto, Danielly Yani;
Bocchi Martins, Julia Beatriz;
Coutinho de Azevedo Guimarães, Adriana

Publication type:

Article

Chatbot-Based Mindfulness-Based Stress Reduction Program for University Students With Depressive Symptoms: Intervention Development and Pilot Evaluation.

Published in:

Journal of the American Psychiatric Nurses Association, 2025, v. 31, n. 4, p. 398, doi. 10.1177/10783903241302092

By:

Li, Yan;
Chung, Tsz Yu;
Lu, Wenze;
Li, Mengqi;
Ho, Ying Wai Bryan;
He, Mengting;
Mei, Xiaoxiao;
Chen, Dapeng;
Bressington, Daniel

Publication type:

Article

Carefix hexaxial spatial frame versus Ilizarov circular external fixator in treating high-energy tibial shaft fractures: a retrospective study.

Published in:

BMC Musculoskeletal Disorders, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12891-025-08867-7

By:

Zhao, Zhiming;
Chen, Xu;
Guo, Feng;
Liu, Yabin;
Shi, Bowen;
Ji, Guoqi;
Cai, Chengkuo;
Xu, Weiguo

Publication type:

Article

Firesorb bioresorbable scaffold for de novo coronary artery disease: 1-year clinical outcomes.

Published in:

BMC Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12916-025-04254-0

By:

Jiang, Jun;
Li, Changling;
Chen, Delong;
Song, Lei;
Cui, Zhanqian;
Li, Ping;
Gan, Lijun;
Chen, Yundai;
Li, Hui;
Jia, Shaobin;
He, Shenghu;
Lu, Wen;
Gao, Runlin;
Wang, Jianan

Publication type:

Article

Effects of branched-chain amino acid- and vitamin D-containing high-protein food supplementation plus exercise on elderly people with decreased physical functions.

Published in:

BMC Geriatrics, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12877-025-06177-0

By:

Nakamura, Yoshihiro;
Yokoe, Takuji;
Ouchi, Koki;
Funamoto, Taro;
Kimura, Hiroyuki;
Hamada, Koichiro;
Arakawa, Hideki;
Chosa, Etsuo;
Kamei, Naosuke

Publication type:

Article

Using an audiovisual feedback device improves cardiopulmonary resuscitation performance during day and night – a randomized controlled simulation study.

Published in:

BMC Emergency Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12873-025-01249-1

By:

Preuss, Melanie;
Röhrig, Rainer;
Hübel, Christian;
Vos, Clara;
Unterkofler, Jenny;
Brokmann, Jörg Christian;
Willmes, Klaus;
Plata, Christopher

Publication type:

Article

A Comparative Study of the Efficacy and Safety Profile of Topical Application of Tranexamic Acid in the Form of Mist to Reduce Postoperative Bleeding in on-Pump CABG Procedures.

Published in:

Annals of Cardiac Anaesthesia, 2025, v. 28, n. 3, p. 287, doi. 10.4103/aca.aca_176_24

By:

Jagadish, Chandrika;
Kumara, Vijaya;
Aspari, Mahammad A.;
Rai, D Guruprasad;
Sumanth, R

Publication type:

Article

Efficacy of systemic therapy on adults with depressive disorders: A meta-analysis.

Published in:

Psychotherapy Research, 2025, v. 35, n. 6, p. 867, doi. 10.1080/10503307.2024.2352741

By:

Vossler, Andreas;
Pinquart, Martin;
Forbat, Liz;
Stratton, Peter

Publication type:

Article

Carboplatin–gemcitabine for refractory high‐grade meningiomas: A study from the French national OMEGA consortium.

Published in:

International Journal of Cancer, 2025, v. 157, n. 5, p. 837, doi. 10.1002/ijc.35453

By:

Larroquette, Mathieu;
Bronnimann, Charlotte;
Ollivier, Morgan;
Daubon, Thomas;
Lesueur, Paul;
Ramirez, Carole;
Idbaih, Ahmed;
Kalamarides, Michel;
Peyre, Matthieu;
Engelhardt, Julien

Publication type:

Article