Works about CELLULAR signal transduction

Results: 5000

Natural products and diet for the prevention of oral cancer: Research from south and southeast Asia.

Published in:

Oral Diseases, 2025, v. 31, n. 5, p. 1503, doi. 10.1111/odi.15002

By:

Malathi, N.;
Rajan, Sharada T.;
Warnakulasuriya, Saman

Publication type:

Article

Small signaling peptides define leaf longevity.

Published in:

Frontiers in Plant Science, 2025, p. 1, doi. 10.3389/fpls.2025.1616650

By:

Qiu, Liping;
Lu, Rong;
Zhang, Ziling;
Nie, Jiaxin;
Wang, Yue;
Liu, Jianping;
Han, Huibin

Publication type:

Article

Mechanisms of vascular endothelial cell injury triggered by blood glucose changes in gestational diabetes mellitus.

Published in:

Diabetes, Obesity & Metabolism, 2025, v. 27, n. 8, p. 4203, doi. 10.1111/dom.16450

By:

Cai, Yuling;
Liu, Jia;
Wang, Qiang;
Ren, Xiujuan;
Xie, Junye;
Yu, Jialing;
Xiao, Yujie;
Zhang, Yibo;
Chen, Xiaojia;
Hong, An

Publication type:

Article

Bone morphogenetic protein 2 rescues neurogenic abnormalities and angiogenic factors in mice with bilateral cavernous nerve injury.

Published in:

Journal of Sexual Medicine, 2025, v. 22, n. 7, p. 1083, doi. 10.1093/jsxmed/qdaf091

By:

Kim, Jong Won;
Chung, Doo Yong;
Liu, Fang-Yuan;
Huang, Yan;
Fridayana, Fitri Rahma;
Vo, Minh Nhat;
Cho, Kang Su;
Ryu, Ji-Kan;
Kwon, Mi-Hye;
Yin, Guo Nan

Publication type:

Article

Cardiac fibroblasts regulate myocardium and coronary vasculature development in the murine heart via the collagen signaling pathway.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.102305

By:

Yiting Deng;
Yuanhang He;
Juan Xu;
Haoting He;
Manling Zhang;
Guang Li

Publication type:

Article

A multi-gene predictive model for the radiation sensitivity of nasopharyngeal carcinoma based on machine learning.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.99849

By:

Kailai Li;
Junyi Liang;
Nan Li;
Jianbo Fang;
Xinyi Zhou;
Jian Zhang;
Anqi Lin;
Peng Luo;
Hui Meng

Publication type:

Article

PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.91779

By:

Antonio Valer, José;
Deber, Alexandre;
Wits, Marius;
Pimenta-Lope, Carolina;
Goumans, Marie-José;
Luis Rosa, Jose;
Sánchez-Duffhues, Gonzalo;
Ventura, Francesc

Publication type:

Article

Identification of genes involved in verazine biosynthesis in Veratrum grandiflorum and their heterologous production in Saccharomyces cerevisiae.

Published in:

BMC Plant Biology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12870-025-06899-8

By:

Hong, Kaiyun;
Liu, Xiangyu;
Wang, Changqing;
Xu, Yanjiao;
Xiang, Guisheng;
Yang, Shengchao;
Yang, Jianli;
Zhang, Guanghui;
He, Simei

Publication type:

Article

Physiological, biochemical, and transcriptomic analyses reveal potential candidate genes of Platostoma palustre in response to salt stress.

Published in:

BMC Plant Biology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12870-025-06858-3

By:

Quan, Changqian;
Huang, Suhua;
Yu, Qiaoling;
Chen, Zhining;
Kashif, Muhammad Haneef;
Xu, Meihua;
Wei, Fan;
Tang, Danfeng

Publication type:

Article

SpoIIIL is a forespore factor required for efficient cell-cell signalling during Bacillus subtilis sporulation.

Published in:

PLoS Genetics, 2025, v. 21, n. 7, p. 1, doi. 10.1371/journal.pgen.1011768

By:

Morales Angeles, Danae;
Coleman, Kaitlyn;
Progress Odika, Chimezie;
Graham, Chris L. B.;
Chan, Helena;
Gilmore, Michael;
Taib, Najwa;
Bauda, Elda;
Moriscot, Christine;
Gallet, Benoit;
Fisher, Hannah;
Bullough, Per A.;
Morlot, Cécile;
Köster, Darius;
Gribaldo, Simonetta;
Cava, Felipe;
Rodrigues, Christopher D. A.

Publication type:

Article

Effects of Pathway Interactions on the Quality of Tan Lamb during Post-slaughter Storage Period.

Published in:

Journal of Chinese Institute of Food Science & Technology / Zhongguo Shipin Xuebao, 2025, v. 25, n. 5, p. 406, doi. 10.16429/j.1009-7848.2025.037

By:

WANG Yanyun;
WANG Jinxia;
LUO Ruiming;
HOU Yanru

Publication type:

Article

Bioprospection of indigenous herbal formulations for diabetes care: in vitro, network pharmacology, and molecular dynamics studies.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04980-1

By:

Ojo, Oluwafemi Adeleke;
Ogunlakin, Akingbolabo Daniel;
Ajayi-Odoko, Omolola Adenike;
Gyebi, Gideon Ampoma;
Ayokunle, Damilare IyinKristi;
Olanrewaju, Adesoji Alani;
Agbeye, Oluwatobi Deborah;
Ogunwale, Emmanuel Tope;
Adeyemi, Oluyomi Stephen

Publication type:

Article

Prediction of the effect of Bupleurum chinensis DC. (Chaihu) on survival and its potential targets in hepatocellular carcinoma based on a prognostic model.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04848-4

By:

Li, Hanhan;
Liu, Shan;
Xiang, Shang;
Guo, Wei;
Huang, Jiayang;
Yu, Ling;
Chen, Zhuangzhong;
lin, Yuan;
Lin, Lizhu;
Chen, Hanrui

Publication type:

Article

Chrysin Counteracts Sodium Hydroxide-Induced Alkali Esophageal Burn by Regulating Beclin-1/HO-1/NQO1, PERK/IRE1-α/ATF-6, Oxidative Stress, Inflammation, Apoptosis Signaling Pathways and Ki-67, EGF Expressions in Rats.

Published in:

Bratislava Medical Journal / Bratislavské Lekárske Listy, 2025, v. 126, n. 7, p. 1278, doi. 10.1007/s44411-025-00127-3

By:

Öztürk, Ayşe Betül;
Şimşek, Hasan;
Akaras, Nurhan;
Kandemir, Fatih Mehmet

Publication type:

Article

When G Protein‐Coupled Receptor Signaling Meets the Primary Cilium: Implications for Sonic Hedgehog Signaling.

Published in:

BioEssays, 2025, v. 47, n. 7, p. 1, doi. 10.1002/bies.70021

By:

Kim, Sung‐Eun

Publication type:

Article

Therapeutic insights and molecular mechanism linking melatonin signaling and membranous nephropathy (Review).

Published in:

Biomedical Reports, 2025, v. 23, n. 2, p. N.PAG, doi. 10.3892/br.2025.2017

By:

Huang, Yen-Sung;
Ka, Shuk-Man;
Lu, Kuo-Cheng;
Chen, Ann;
Wu, Chia-Chao

Publication type:

Article

Silencing of AEBP1 inhibits proliferation and promotes apoptosis via the AKT signaling pathway in osteosarcoma.

Published in:

Biomedical Reports, 2025, v. 23, n. 2, p. N.PAG, doi. 10.3892/br.2025.2006

By:

Jia, Cunfeng;
Gong, Zhen;
Zhang, Lei

Publication type:

Article

Molecular mechanisms underlying the early steps of floral initiation in seasonal flowering genotypes of cultivated strawberry.

Published in:

Frontiers in Plant Science, 2025, p. 1, doi. 10.3389/fpls.2025.1563658

By:

Ziegler, Freya Maria Rosemarie;
Gaston, Amelia;
Guy, Karine;
Devers, Marie;
Krüger, Erika;
Brauksiepe, Bastienne;
Eimert, Klaus;
Osorio, Sonia;
Denoyes, Béatrice;
Usadel, Björn

Publication type:

Article

P4HA2 promotes the progression of papillary thyroid cancer by enhancing degradation of IκBα to activate NF-κB signaling pathway.

Published in:

Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03871-2

By:

Li, Ruowen;
Zhao, Mingjian;
Sun, Min;
Wu, Yongkang;
Miao, Chengxu;
Fangyu, Liu;
Wu, Mengting;
Shi, Xiaojia;
Lu, Jinghui;
Yue, Xuetian

Publication type:

Article

Nano-selenium and the SRC family kinases pathway: Redefining gene expression dynamics in major depressive disorder based on a randomized controlled trial.

Published in:

Current Journal of Neurology, 2024, v. 23, n. 4, p. 240, doi. 10.18502/cjn.v23i4.18767

By:

Noormohammadi, Morvarid;
Etesam, Farnaz;
Amini, Ali;
Khosravian, Pegah;
Mohammadzadeh, Morteza;
Shidfar, Farzad

Publication type:

Article

Royal jelly fermented by honeybee queen (Apis mellifera)-derived Lactobacillus panisapium M1 enhances macrophage phagocytosis through the TLR2/MAPK/SR signaling pathway.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04976-x

By:

Nonobe, Shuhei;
Okamoto, Hideto;
Ito, Takashi;
Itatani, Hayate;
Yamaki, Ayanori;
Okumura, Nobuaki

Publication type:

Article

Anti-cancer effects of genistein supplementation and moderate-intensity exercise in high-fat diet-induced breast cancer via regulation of inflammation and adipose tissue metabolism in vivo and in vitro.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04968-x

By:

Kwon, Hyeji;
Han, Hyejin;
Oh, Yeonsoo;
Kim, Yuri;
Kim, Jung-Hyun

Publication type:

Article

Anticancer and cancer preventive activities of shogaol and curcumin from Zingiberaceae family plants in KG-1a leukemic stem cells.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04829-7

By:

Panyajai, Pawaret;
Viriyaadhammaa, Natsima;
Chiampanichayakul, Sawitree;
Sakamoto, Yasuhisa;
Okonogi, Siriporn;
Moroishi, Toshiro;
Anuchapreeda, Songyot

Publication type:

Article

Peripheral Blood-Derived Mesenchymal Stem Cells Promote A2 Phenotype Polarization in Astrocytes via TGF-β-Mediated PI3K/Akt Pathway Activation.

Published in:

European Journal of Medical Research, 2025, v. 30, n. 1, p. 1, doi. 10.1186/s40001-025-02814-x

By:

Yang, Rui-Lin;
Zhao, De-Zhi;
Wei, Han-Xiao;
Chen, Si-Yu;
Yang, Yi-Bing;
Yang, Kang;
Yan, Wen;
Zhang, Tao

Publication type:

Article

ER-related E2-E3 ubiquitin enzyme pair regulates ethylene response by modulating the turnover of ethylene receptors.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61066-9

By:

Zhao, Qingcui;
Zhou, Xiaofeng;
Chen, Qian;
Yang, Ruoyun;
Li, Yonghong;
Zhao, Jiaxin;
Fu, Xijia;
Lin, Yan;
Liu, Yuming;
Zhao, Liangjun;
Jiang, Cai-Zhong;
Gan, Su-Sheng;
Xie, Qi;
Gao, Junping;
Ma, Nan

Publication type:

Article

Aberrant angiogenic signaling in HCC: therapeutic targeting and drug resistance.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1595195

By:

Zhang, Hongtao;
Yang, Zhaoming;
Jiang, Zhengwu;
Zhao, Zhijian;
Chen, Xun;
Wan, Jian;
Li, Yukun

Publication type:

Article

The plasma proteome reveals distinct signaling pathways associated with PR3-ANCA positive and MPO-ANCA positive vasculitis.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1600754

By:

Hellbacher, Erik;
van Hoef, Vincent;
Johansson, Alina;
Knight, Ann;
Gunnarsson, Iva;
Bruchfeld, Annette;
Eriksson, Per;
Ohlsson, Sophie;
Rantapää-Dahlqvist, Solbritt;
Dahlqvist, Johanna

Publication type:

Article

Biomarkers for intensive care unit-acquired weakness: a systematic review for prediction, diagnosis and prognosis.

Published in:

Annals of Intensive Care, 2025, v. 15, n. 1, p. 1, doi. 10.1186/s13613-025-01500-9

By:

Song, Jiamei;
Deng, Ting;
Yu, Qingmei;
Luo, Xun;
Miao, Yanmei;
Xie, Leiyu;
Mei, Yongming;
Xie, Peng;
Chen, Shaolin

Publication type:

Article

Multi-omics and network pharmacology reveal Huayu-Tongbi decoction reduced arthritis-related bone erosion.

Published in:

Chinese Medicine, 2025, v. 20, p. 1, doi. 10.1186/s13020-025-01159-1

By:

Chen, Bozhen;
Yang, Lu;
Wang, Houchun;
Yu, Peng;
Ma, Mengyang;
Chen, Meiqi;
Zhou, Yingyan;
Wu, Jiaqi;
Liang, Huasheng;
Wang, Maojie;
Huang, Runyue;
He, Yiting;
Huang, Qingchun;
He, Xiaohong

Publication type:

Article

Hederasaponin C ameliorates chronic obstructive pulmonary disease pathogenesis by targeting TLR4 to inhibit NF-κB/MAPK signaling pathways.

Published in:

Chinese Medicine, 2025, v. 20, p. 1, doi. 10.1186/s13020-025-01155-5

By:

Ning, Yujie;
Huang, Liting;
Wang, Qin-Qin;
Liu, Lina;
Ni, Xinghua;
Xie, Xiaoyun;
Liu, Jingyu;
Su, Qian;
Yang, Shilin;
Yuan, Renyikun;
Gao, Hongwei

Publication type:

Article

Aloe vera-derived extracellular vesicle-like particles suppress pancreatic carcinoma progression through triggering pyroptosis via ROS-GSDMD/E signaling pathway.

Published in:

Chinese Medicine, 2025, v. 20, p. 1, doi. 10.1186/s13020-025-01153-7

By:

Shen, Jieyu;
Wei, Tianfu;
Li, Mingchen;
Jiang, Yuankuan;
Zhang, Jiahui;
Qi, Yueyi;
Chen, Cai;
Li, Xiaojie;
Huang, Peng;
Qu, Jialin

Publication type:

Article

Mechanistic insights into the Bushen Huatan Huoxue Formula and its components in ameliorating obesity-associated polycystic ovary syndrome.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01165-3

By:

Jin, Yu-Xin;
Hu, Hang-Qi;
Zhang, Jia-Cheng;
Zhu, Yu-Tian;
Zhang, Hao-Lin;
Xin, Xi-Yan;
Fan, Rui-Wen;
Ye, Yang;
Li, Yin;
Li, Dong

Publication type:

Article

Decoding the anti-thrombotic effects of leonurine: a multimodal approach combining TCM repositioning and mTOR signaling.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01160-8

By:

Dong, Xin;
Jia, Shuaibing;
Zhang, Leifeng;
Liang, Yong;
Zhang, Jianhua;
Zhu, Yi Zhun

Publication type:

Article

A computational-based new treatment strategy with three-armed RCT on Mycoplasma pneumoniae pneumonia in children.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01149-3

By:

Zhong, Chengliang;
Liu, Qingyuan;
Guo, Shengxuan;
Sun, Deyang;
Wang, Boyang;
Hu, Siyuan;
Li, Xinmin;
Zhao, Weibo;
Ding, Ying;
Yuan, Bin;
Liu, Jing;
Xiang, Long;
Li, Nan;
Xue, Zheng;
Li, Yan;
Teng, Yiqun;
Yi, Rongsong;
Li, Shao;
Ma, Rong

Publication type:

Article

Exploring the mechanism of Synechococcus sp. XM-24 in gastric cancer treatment via network pharmacology and molecular docking.

Published in:

PLoS ONE, 2025, v. 20, n. 7, p. 1, doi. 10.1371/journal.pone.0326664

By:

Li, Jiayi;
Ma, Yamei;
Guo, Longzhi;
Liu, Junhong;
Li, Lin

Publication type:

Article

PLZF promotes compensatory lung growth by increasing HPMEC proliferation and angiogenesis.

Published in:

PLoS ONE, 2025, v. 20, n. 7, p. 1, doi. 10.1371/journal.pone.0325936

By:

Peng, Jing;
Ma, Liang;
Wang, Zhonghui;
Du, Yaxi;
Tao, Qunfen;
Wang, Qiongchuan;
Zhao, Li

Publication type:

Article

Protective Effect of Lycopene on Ifosfamide-Induced Mitophagy through Pink, Parkin, and LC3-I/II Pathway in Testicular Tissue.

Published in:

International Journal of Fertility & Sterility, 2025, v. 19, n. 3, p. 319, doi. 10.22074/IJFS.2024.2036627.1740

By:

Imeer, Ali Thoulfikar A.;
Rad, Moona Roshanfekr;
Abedi, Sara

Publication type:

Article

Integrated analyses to explore the mechanism of Gancao Renshen Zhixue Decoction in treating liver cirrhosis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-09206-5

By:

Pan, Junwei

Publication type:

Article

Identification and verification of oxidative stress-related genes in the diagnosis of osteoporosis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-06118-2

By:

Liu, Zhenchuan;
Yang, Xu;
Wang, Zexin;
Li, Qi;
Gu, Hanwen;
Meng, Qunbo;
Zhang, Yuanqiang

Publication type:

Article

Composite microRNA–genetic risk score model links to migraine and implicates its pathogenesis.

Published in:

Brain: A Journal of Neurology, 2025, v. 148, n. 6, p. 2178, doi. 10.1093/brain/awaf005

By:

Chen, Shih-Pin;
Chang, Ya-Hsuan;
Wang, Yen-Feng;
Chen, Hsuan-Yu;
Wang, Shuu-Jiun

Publication type:

Article

Recent Advances in Management of Vitiligo.

Published in:

Indian Journal of Dermatology, 2025, v. 70, n. 4, p. 201, doi. 10.4103/ijd.ijd_158_25

By:

Das, Kinnor;
Sarkar, Rashmi;
Sinha, Surabhi

Publication type:

Article

CALR regulates the proliferation and drug sensitivity of multiple myeloma cells through the BCL2 signaling pathway.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10749-z

By:

Wang, Yin;
Hu, Xiaoli;
Song, Yaqi;
Ruan, Qianqi;
Bai, Xiaoteng;
Du, Juan

Publication type:

Article

Wnt/Ca<sup>2+</sup> signaling: Dichotomous roles in regulating tumor progress (Review).

Published in:

Oncology Letters, 2025, v. 30, n. 2, p. N.PAG, doi. 10.3892/ol.2025.15145

By:

Jing, Licong;
Wang, Hui;
Xia, Sheng;
Shao, Qixiang

Publication type:

Article

[Retracted] Everolimus inhibits the proliferation and migration of epidermal growth factor receptor-resistant lung cancer cells A549 via regulating the microRNA-4328/phosphatase and tensin homolog signaling pathway.

Published in:

2025

By:

Xiang, Xudong;
Zhuang, Li;
Chen, Huicheng;
Yang, Xiumei;
Li, Heng;
Li, Gaofeng;
Yu, Jing

Publication type:

Correction Notice

IGFBP3 modulation of tumor pathogenesis and cell signaling pathways (Review).

Published in:

Oncology Letters, 2025, v. 30, n. 2, p. N.PAG, doi. 10.3892/ol.2025.15125

By:

Zhang, Yanzi;
Lv, Xin

Publication type:

Article

L-Phenylalanine promotes liver steatosis by inhibiting BNIP3-mediated mitophagy.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01303-5

By:

Sun, Ying;
Cai, Lingli;
Yu, Bowei;
Zhang, Haojie;
Zhang, Ziteng;
Xu, Xiaoqin;
Yu, Yuefeng;
Li, Jiang;
Chen, Chi;
Xia, Fangzhen;
Lu, Yingli;
Zhang, Kun;
Wang, Ningjian

Publication type:

Article

The impact of pharmacological agents on neuroinflammation in neurodegenerative diseases.

Published in:

Acta Marisiensis. Seria Medica, 2025, v. 71, n. 2, p. 95, doi. 10.2478/amma-2025-0018

By:

Sharma, Anurag;
Khan, Zoya;
Nath, Rajendra;
Dixit, Rakesh Kumar

Publication type:

Article

Liver Toxicity Induced by Exposure to Bisphenol Analogs at Environmentally Relevant Levels: Insights from a Literature Review on Multiple Species.

Published in:

Livers, 2025, v. 5, n. 2, p. 24, doi. 10.3390/livers5020024

By:

Guo, Tai L.;
Eldefrawy, Fatma;
Guo, Kevin M.

Publication type:

Article

Comparison of Differentially Expressed Genes in Human Versus in Chimeric Mouse Livers Following HBV Infection.

Published in:

Livers, 2025, v. 5, n. 2, p. 18, doi. 10.3390/livers5020018

By:

Bao, Huarui;
Tsuge, Masataka;
Murakami, Serami;
Fujii, Yasutoshi;
Uchikawa, Shinsuke;
Fujino, Hatsue;
Ono, Atsushi;
Murakami, Eisuke;
Kawaoka, Tomokazu;
Miki, Daiki;
Hayes, Clair Nelson;
Oka, Shiro

Publication type:

Article

Three-Dimensional Hydrogel Culture Reveals Novel Differentiation Potential of Human Bone Marrow-Derived Stem Cells.

Published in:

Prosthesis (2673-1592), 2025, v. 7, n. 3, p. 52, doi. 10.3390/prosthesis7030052

By:

Lee, Hye Jeong;
Lau, Le Na;
Sidhu, Sharanbir K.;
Park, Joo-Young;
Yeo, In-Sung Luke

Publication type:

Article