Works matching DE "CELLULAR signal transduction"

Results: 5000

The OT-II model reveals dual in vitro and in vivo immunomodulatory properties of CD6 in T cell activation.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1571590

By:

Leyton-Pereira, Alejandra;
Fernández-Delgado, Irene;
Rodríguez-Lagunas, María José;
Català, Cristina;
Casadó-Llombart, Sergi;
Martin-Cofreces, Noa Beatriz;
Bustos-Morán, Eugenio;
Díaz-Garrido, Natalia;
Consuegra-Fernández, Marta;
Calpena, Ana Cristina;
Aranda, Fernando;
Andrés, María Velasco-de;
Baldomà, Laura;
Sánchez-Madrid, Francisco;
Lozano, Francisco

Publication type:

Article

The molecular logic of Gtr1/2- and Pib2-dependent TORC1 regulation in budding yeast.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.94628

By:

Cecil, Jacob H.;
Padilla, Cristina M.;
Lipinski, Austin A.;
Langlais, Paul;
Xiangxia Luo;
Capaldi, Andrew P.

Publication type:

Article

Drosophila hamlet mediates epithelial tissue assembly of the reproductive system.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104164

By:

Huazhen Wang;
Bertonnier-Brouty, Ludivine;
Artner, Isabella;
Jiayu Wen;
Qi Dai

Publication type:

Article

Pharmacological inhibition of the cGAS-STING pathway suppresses microglia pyroptosis in sepsis-associated encephalopathy.

Published in:

Journal of Neuroinflammation, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12974-025-03507-2

By:

Zeng, Qing-quan;
Qi, Yang;
Yu, Hui;
Xu, Ying;
Chen, Jin-xing;
Zheng, You-wei;
Zhang, Gui-fei;
Zhang, Qiao-ling;
Zheng, Yan-hua;
Guo, Jing;
Zhao, Zi-hong;
Wang, Fa-sheng;
Jin, Gui-lin

Publication type:

Article

Epimedium Brevicornu and Curculigo orchioides inhibit osteoclast autophagy by degrading the level of miRNA-199 to regulate the mTOR signaling pathway.

Published in:

Journal of Orthopaedic Surgery & Research, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13018-025-06043-0

By:

Shi, Mengyao;
Sun, Peng;
Chai, Fang

Publication type:

Article

Thymol Improves Brain Functional Outcomes after Cerebral Ischemia-Reperfusion Injury by Regulating p38 MAPK Associated Apoptosis Signalling Pathway.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2025, v. 59, n. 2, p. 790, doi. 10.5530/ijper.20257027

By:

Mukkudiahgari, Hima Saila;
Kudamala, Ramesh Reddy;
Thakur, Santhrani

Publication type:

Article

Berberine hinders the malignant progression of non-small cell lung cancer via regulating E2F1/FZD8 signaling pathway.

Published in:

Applied Biological Chemistry, 2025, v. 68, n. 1, p. 1, doi. 10.1186/s13765-025-01013-w

By:

Liu, Shenping;
Tang, Chunmei

Publication type:

Article

"Cyclic nucleotides in plants: from obscure messengers to central regulators".

Published in:

Frontiers in Plant Science, 2025, p. 1, doi. 10.3389/fpls.2025.1618243

By:

Świeżawska-Boniecka, Brygida;
Szmidt-Jaworska, Adriana

Publication type:

Article

Genotype-dependent responses to HIPV exposure in citrus: repression of CsPUB21 and activation of SA/JA signaling.

Published in:

Frontiers in Plant Science, 2025, p. 1, doi. 10.3389/fpls.2025.1605151

By:

Ortells-Fabra, Raúl;
Gallego-Giraldo, Carolina;
Forner-Giner, Maria Angeles;
Urbaneja, Alberto;
Pérez-Hedo, Meritxell

Publication type:

Article

RBP7 knockdown inhibits proliferation of human hepatocellular carcinoma and activates the p38 MAPK pathway.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1592616

By:

Li, Jinhai;
Zhai, Huawei;
Cai, Fujing;
Zhang, Xian;
Zhou, Yu;
Li, Shuqun;
Song, Huachun;
Zhang, Haifeng;
Sun, Guangzheng;
Zhu, Minghui;
Yuan, Jing;
Zhang, Ningxin;
Yan, Maolin

Publication type:

Article

SIRT7 deletion inhibits Glaesserella parasuis -mediated inflammatory responses in porcine alveolar macrophages.

Published in:

Frontiers in Cellular & Infection Microbiology, 2025, p. 1, doi. 10.3389/fcimb.2025.1589199

By:

Zheng, Hao;
Wang, Baoxin;
Dong, Xia;
Wu, Junjing;
Shi, Liangyu;
Zhang, Jing;
Chen, Hongbo;
Zhou, Ao

Publication type:

Article

In This Issue.

Published in:: Arthritis & Rheumatology, 2025, v. 77, n. 6, p. 1, doi. 10.1002/art.43251
Publication type:: Article

Disturbed Spatial WNT Activation—A Potential Driver of the Reticularized Skin Phenotype in Systemic Sclerosis.

Published in:

Arthritis & Rheumatology, 2025, v. 77, n. 6, p. 740, doi. 10.1002/art.43094

By:

Fakhouri, Sara Chenguiti;
Zhu, Honglin;
Li, Yi‐Nan;
Ronicke, Moritz;
Rigau, Aleix Rius;
Dees, Clara;
Konstantinidis, Laura;
Schmid, Ralf;
Matei, Alexandru‐Emil;
Eckstein, Markus;
Geppert, Carol;
Ludolph, Ingo;
Kreuter, Alexander;
Sticherling, Michael;
Berking, Carola;
Horch, Raymund E.;
Schett, Georg;
Distler, Jörg H. W.;
Bergmann, Christina

Publication type:

Article

Endogenous Retroelement Activation is Implicated in Interferon‐α Production and Anti–Cyclic Citrullinated Peptide Autoantibody Generation in Early Rheumatoid Arthritis.

Published in:

Arthritis & Rheumatology, 2025, v. 77, n. 6, p. 646, doi. 10.1002/art.43083

By:

Cooles, Faye A. H.;
Vidal Pedrola, Gemma;
Naamane, Najib;
Pratt, Arthur G.;
Barron‐Millar, Ben;
Anderson, Amy E.;
Hilkens, Catharien M. U.;
Casement, John;
Bondet, Vincent;
Duffy, Darragh;
Zhang, Fan;
Shukla, Ruchi;
Isaacs, John D.

Publication type:

Article

Topical Mupirocin Treatment Reduces Interferon and Myeloid Signatures in Cutaneous Lupus Erythematous Lesions Through Targeting of Staphylococcus Species.

Published in:

Arthritis & Rheumatology, 2025, v. 77, n. 6, p. 705, doi. 10.1002/art.43079

By:

Abernathy‐Close, Lisa;
Mears, Joseph;
Billi, Allison C.;
Sirobhushanam, Sirisha;
Berthier, Celine;
Lu, Annie;
Zhang, Zeran;
Hurst, Amy;
Gudjonsson, Johann E.;
Kahlenberg, J. Michelle

Publication type:

Article

4‐Phenyl Butyric Acid (4‐PBA) Suppresses Neutrophil Recruitment in a Murine Model of Acute Perinatal Inflammation.

Published in:

Journal of Immunology Research, 2025, v. 2025, p. 1, doi. 10.1155/jimr/2438058

By:

Gille, Christian;
Jungwirth, Maylis;
Pezer, Silvia;
Dietz-Ziegler, Stefanie;
Köstlin-Gille, Natascha;
Lajqi, Trim;
Gurumallesh, Poorani

Publication type:

Article

Natural products and diet for the prevention of oral cancer: Research from south and southeast Asia.

Published in:

Oral Diseases, 2025, v. 31, n. 5, p. 1503, doi. 10.1111/odi.15002

By:

Malathi, N.;
Rajan, Sharada T.;
Warnakulasuriya, Saman

Publication type:

Article

Abscopal Effects and Immunomodulation in Skin Cancer Therapy.

Published in:

American Journal of Clinical Dermatology, 2025, v. 26, n. 4, p. 555, doi. 10.1007/s40257-025-00943-x

By:

Nahm, William J.;
Sakunchotpanit, Goranit;
Nambudiri, Vinod E.

Publication type:

Article

S-palmitoylation: a novel insight in the development and immunotherapy of oral squamous cell carcinoma.

Published in:

Journal of Cancer, 2025, v. 16, n. 9, p. 2787, doi. 10.7150/jca.110721

By:

Xue-ting Yuan;
Jing-ru Wang;
Ying Yang;
Jian-gang Ren

Publication type:

Article

HnRNP-F promotes the proliferation of bladder cancer cells mediated by PI3K/AKT/FOXO1.

Published in:

Journal of Cancer, 2021, v. 12, n. 1, p. 281, doi. 10.7150/jca.50490

By:

Fei Li;
Weiwei Xie;
Yunze Fang;
Kunfeng Xie;
Wendong Liu;
Lina Hou;
Wanlong Tan

Publication type:

Article

ALKAL1 gene silencing prevents colorectal cancer progression via suppressing Sonic Hedgehog (SHH) signaling pathway.

Published in:

Journal of Cancer, 2021, v. 12, n. 1, p. 150, doi. 10.7150/jca.46447

By:

Shasha Chen;
Bin Wang;
Xuekun Fu;
Yanfang Liang;
Xingxing Chai;
Ziyu Ye;
Ronggang Li;
Yaoming He;
Gang Kong;
Jiachun Lian;
Xiangyong Li;
Ting Chen;
Xin Zhang;
Xianxiu Qiu;
Xudong Tang;
Keyuan Zhou;
Bihua Lin;
Jincheng Zeng

Publication type:

Article

U three protein 14a (UTP14A) promotes tumour proliferation and metastasis via the PERK/eIF2a/GRP78 signalling pathway in oesophageal squamous cell carcinoma.

Published in:

Journal of Cancer, 2021, v. 12, n. 1, p. 134, doi. 10.7150/jca.44649

By:

Kun-Kun Li;
Cheng-Yi Mao;
Qiang Ma;
Tao Bao;
Ying-Jian Wang;
Wei Guo;
Xiao-Long Zhao

Publication type:

Article

Distinct structural mechanisms of LGR4 modulation by Norrin and RSPOs in Wnt/β-catenin signaling.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61545-z

By:

Qiao, Huarui;
Hu, Fangzheng;
Wang, Yiang;
Wang, Lu;
Zhou, Siyu;
Guo, Shaojue;
Xu, Yiwen;
Xu, Jianfeng;
Cui, Qianqian;
Yang, Qilun;
Xu, H. Eric;
Zhu, Jianwei;
Geng, Yong

Publication type:

Article

SPTSSA facilitates gastric cancer progression with modulating PD-L1 in immunomicroenvironment through Wnt/β-catenin pathway.

Published in:

Cellular Oncology (2211-3428), 2025, v. 48, n. 4, p. 1127, doi. 10.1007/s13402-025-01072-7

By:

Sun, Pingping;
Qin, Weiwei;
Xu, Haiyan;
Yin, Hang;
Yang, Lei;
Zhang, Xiaojing;
Jin, Xiaoxia;
Xu, Qiang;
Wu, Han;
Kuai, Xiaoling;
Jia, Lizhou;
Huang, Jianfei;
Wang, Yao

Publication type:

Article

Juanbi Qianggu Formula inhibits fibroblast-like synovicytes activation via repressing LncRNA ITSN1-2 to promote RIP2 K48 ubiquitination.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01164-4

By:

Bian, Yanqin;
Li, Fang;
A, Xinyu;
Xiang, Zheng;
Ma, Nanshan;
Wang, Jianye;
Cao, Boran;
Xin, Pengfei;
Cheng, Xuan;
Liu, Chang;
Xiang, Bei;
Shen, Jun;
Lu, Qigui;
Xiao, Lianbo

Publication type:

Article

Buyang Huanwu Decoction improves energy metabolism disorders after cerebral ischemia–reperfusion by regulating the SIRT1/AMPK signaling pathway to promote glycolysis and the tricarboxylic acid cycle.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01163-5

By:

Hu, Zhongji;
Deng, Nujiao;
Li, Yanling;
Bai, Yang;
Lan, Xiao;
Xiong, Tingting;
Ding, Huang;
Liu, Xiaodan;
Deng, Changqing

Publication type:

Article

Biochanin A Ameliorates Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice by Modulating the NF-κB and MAPK Signaling Pathways.

Published in:

Inflammation, 2025, v. 48, n. 3, p. 1125, doi. 10.1007/s10753-024-02103-5

By:

Walvekar, Komal Paresh;
Tirunavalli, Satya Krishna;
Eedara, Abhisheik Chowdary;
Chandra, Yogesh;
Kuncha, Madhusudhana;
B.R.Kumar, Ashwin;
Sistla, Ramakrishna;
Andugulapati, Sai Balaji;
Chilaka, Sabarinadh

Publication type:

Article

Therapeutic Effect of Melatonin on CCl4-Induced Fibrotic Liver Model by Modulating Oxidative Stress, Inflammation, and TGF-β1 Signaling Pathway in Pinealectomized Rats.

Published in:

Inflammation, 2025, v. 48, n. 3, p. 1093, doi. 10.1007/s10753-024-02101-7

By:

Cinar, Derya;
Altinoz, Eyup;
Elbe, Hulya;
Bicer, Yasemin;
Cetinavci, Dilan;
Ozturk, Ipek;
Colak, Tuncay

Publication type:

Article

A new pathway for neuroprotection against tau hyperphosphorylation via δ-opioid receptor initiated inhibition of CDK5 and AMPK signaling.

Published in:

Frontiers in Aging Neuroscience, 2025, p. 1, doi. 10.3389/fnagi.2025.1587219

By:

Li, Jiahui;
Xu, Yuan;
Balboni, Gianfranco;
Xia, Ying

Publication type:

Article

SEQUENCE CHARACTERISTICS AND EXPRESSION LOCALIZATION ANALYSIS OF INTERCELLULAR ADHESION MOLECULES 2.

Published in:

JAPS: Journal of Animal & Plant Sciences, 2025, v. 35, n. 3, p. 660, doi. 10.36899/japs.2025.3.0055

By:

Zhang, X.;
Huo, H.L.;
Chen, Y.Y.;
Huo, J.L.

Publication type:

Article

The Prognostic Significance of TMSB4X in Glioma Patients.

Published in:

International Journal of General Medicine, 2025, v. 18, p. 2923, doi. 10.2147/IJGM.S521390

By:

Li, Sijie;
Fan, Tianyi;
Hao, Zengyao;
Zhang, Zizhou;
Han, Xuetao;
Li, Jiayuan;
Wang, Yu;
Zhou, Huandi;
Xue, Xiaoying

Publication type:

Article

Mechanisms and Recent Advances of Small-Molecule Therapeutics in Rosacea Treatment.

Published in:

Clinical, Cosmetic & Investigational Dermatology, 2025, v. 18, p. 1459, doi. 10.2147/CCID.S525787

By:

Ye, Maogen;
Hao, Pingsheng;
Luo, Nana;
Li, Tianhao

Publication type:

Article

Glut-1 exerts anti-tumor activity in glioma by regulating AKT / mTOR signaling pathway.

Published in:

Technology & Health Care, 2025, v. 33, n. 4, p. 1693, doi. 10.1177/09287329241304910

By:

Li, Zhimei;
Zhang, Guofeng

Publication type:

Article

TLR2 and TLR4 bridge physiological and pathological inflammation in the reproductive system.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08424-x

By:

Mansouri, Alireza;
Akthar, Ihshan;
Miyamoto, Akio

Publication type:

Article

Neutrophil extracellular trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting pancreatic tumour metastasis.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08440-x

By:

McDonald, Paul C.;
Topham, James T.;
Awrey, Shannon;
Tavakoli, Hossein;
Carroll, Rebekah;
Brown, Wells S.;
Gerbec, Zachary J.;
Kalloger, Steve E.;
Karasinska, Joanna M.;
Tang, Patricia;
Goodwin, Rachel;
Jones, Steven J. M.;
Laskin, Janessa;
Marra, Marco A.;
Morin, Gregg B.;
Renouf, Daniel J.;
Schaeffer, David F.;
Dedhar, Shoukat

Publication type:

Article

How epigenetics and miRNA affect gene expression in dental pulp inflammation: A narrative review.

Published in:

International Endodontic Journal, 2025, v. 58, n. 6, p. 833, doi. 10.1111/iej.14211

By:

Väisänen, Milo;
Siukosaari, Päivi;
Tjäderhane, Leo

Publication type:

Article

Network pharmacology-based insights into the role of gut microbiota metabolites in insulin resistance.

Published in:

Frontiers in Microbiology, 2025, p. 1, doi. 10.3389/fmicb.2025.1617496

By:

Xiao, Bing;
Chen, Xin;
Zong, Ruiyu;
Guan, Yiming;
Zhu, Zhu;
Bi, Siling

Publication type:

Article

Early diagnosed Zaki syndrome: identification of two novel WLS variants and a literature review.

Published in:

Italian Journal of Pediatrics, 2025, v. 51, n. 1, p. 1, doi. 10.1186/s13052-025-02067-8

By:

Tian, Anran;
Li, Sujuan;
Liang, Furong;
Yao, Minglan;
Mostafavi, Niusha;
Li, Yingying;
Luo, Xiaoping;
Zhang, Cai

Publication type:

Article

Mechanistic study of CTHRC1 in promoting Wilms' tumor progression by regulating M2-type tumor-associated macrophages polarization.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06752-4

By:

Zhuo, Yingquan;
Feng, Xiaoyun;
Zhang, Wenqi;
Du, Jun;
Sun, Xu;
Luo, Xi;
Wang, Wei;
Jiang, Hua;
Gu, Huajian

Publication type:

Article

A review on mesenchymal stem cells and their secretome in hepatocellular carcinogenesis and its related signaling pathways: recent update.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03088-9

By:

Jayachandran, Jayenth;
Rithi, A. T.;
Mitra, Abhijit;
Radhakrishnan, Arunkumar;
Banerjee, Antara;
Duttaroy, Asim K.

Publication type:

Article

CRISPRi knockdown of mycobacterial tkt gene potentiates the anti-mycobacterial activity of phyto-compounds from selected medicinal plants.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04987-8

By:

Matotoka, Mashilo Mash;
Mashabela, Gabriel Tshwahla;
Masoko, Peter

Publication type:

Article

The P53N236S Mutation Plays a Regulatory Role in Osteosarcoma Metastasis Via the Cholesterol-Hedgehog Pathway.

Published in:

Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2025, v. 59, n. 3, p. 375, doi. 10.33594/000000780

By:

Wang Lulin;
Liu Jiawei;
Zhang Shuojie;
Xie Xiaoli;
Wang Hui;
Jia Jing;
Dan Juhua

Publication type:

Article

Role of endoplasmic reticulum stress on formaldehyde-exacerbated allergic asthma in mice.

Published in:

Toxicology Research, 2025, v. 14, n. 3, p. 1, doi. 10.1093/toxres/tfaf066

By:

Zhang, Yuchao;
Guo, Yutong;
Liu, Liangyu;
Xia, Wei;
Wang, Yi;
Liu, Mengyin;
Lin, Dayuan;
Li, Jiaxing;
Zhao, Yuanchao;
Zhu, Sijie;
Liu, Xudong

Publication type:

Article

Unveiling the Therapeutic Potential of Piper chaba Hunter: Computational Approaches Shed Light on Targeting Proteins in Alzheimer's Disease.

Published in:

BioMed Research International, 2025, v. 2025, p. 1, doi. 10.1155/bmri/8892801

By:

Rahi, Md. Sifat;
Rahman, Md. Shahedur;
Meem, Rima Islam;
Shimul, Md. Ebrahim Khalil;
Farnaj, Nahid;
Kabir, Md. Humaun;
Ahmed, Fee Faysal;
Parvez, Md. Anowar Khasru;
Huq, Md. Amdadul;
Kabir, Tabassum;
Harrath, Abdel Halim;
Hasan, Mahadi;
Rahman, Md. Ataur;
Siddique, Muhammad Hussnain

Publication type:

Article

Role of Kctd13 in modulating AR and SOX9 expression in different penile cell populations.

Published in:

Andrology, 2025, v. 13, n. 5, p. 1201, doi. 10.1111/andr.70005

By:

Jorgez, Carolina J.;
Chahdi, Ahmed;
Flores, Hunter;
O'Neill, Marisol;
Seth, Abhishek

Publication type:

Article

Ganoderma Spore Lipids Inhibit Perineural Invasion in Pancreatic Cancer by Downregulating NGF-TrkA Pathway.

Published in:

Journal of Evidence-Based Integrative Medicine, 2025, p. 1, doi. 10.1177/2515690X251356473

By:

Lin, Haohui;
Chung, Manhon;
Yang, Yi;
Zhang, Li;
Pan, Xiaohua;
Cai, Sa;
Pan, Yu

Publication type:

Article

Supramolecular Ion Channels to Engineer Zn2+ Ion Transport Mediated Chemical‐to‐Optical Signal Transduction.

Published in:

Angewandte Chemie, 2025, v. 137, n. 28, p. 1, doi. 10.1002/ange.202501634

By:

Srimayee, Soumya;
Prusty, Biswa Mohan;
Kar, Mrinal Kanti;
Winterhalter, Mathias;
Manna, Debasis

Publication type:

Article

Abscisic acid enhances non-photochemical quenching through SnRK2 and ABI3 in Physcomitrium patens.

Published in:

Journal of Plant Research, 2025, v. 138, n. 4, p. 625, doi. 10.1007/s10265-025-01627-7

By:

Maeng, Chang-Hyun;
Fujita, Takuya;
Kishimoto, Junko;
Tanaka, Ryouichi;
Takabayashi, Atsushi;
Fujita, Tomomichi

Publication type:

Article

Small signaling peptides define leaf longevity.

Published in:

Frontiers in Plant Science, 2025, p. 1, doi. 10.3389/fpls.2025.1616650

By:

Qiu, Liping;
Lu, Rong;
Zhang, Ziling;
Nie, Jiaxin;
Wang, Yue;
Liu, Jianping;
Han, Huibin

Publication type:

Article

Mechanisms of vascular endothelial cell injury triggered by blood glucose changes in gestational diabetes mellitus.

Published in:

Diabetes, Obesity & Metabolism, 2025, v. 27, n. 8, p. 4203, doi. 10.1111/dom.16450

By:

Cai, Yuling;
Liu, Jia;
Wang, Qiang;
Ren, Xiujuan;
Xie, Junye;
Yu, Jialing;
Xiao, Yujie;
Zhang, Yibo;
Chen, Xiaojia;
Hong, An

Publication type:

Article