Works matching DE "CELLULAR aging"

Results: 5000

Aging's impact on the immune system.

Published in:

2025

By:

Gearhart, Patricia J

Publication type:

Editorial

General and individualized changes in T cell immunity during aging.

Published in:

Journal of Immunology, 2025, v. 214, n. 5, p. 872, doi. 10.1093/jimmun/vkae033

By:

Song, Nianbin;
Elbahnasawy, Mostafa A;
Weng, Nan-Ping

Publication type:

Article

Identification and validation of key genes involved in cellular senescence in multiple sclerosis using bioinformatics.

Published in:

Journal of Chinese Pharmaceutical Sciences, 2025, v. 34, n. 6, p. 530, doi. 10.5246/jcps.2025.06.040

By:

Xiaoqin Zhang;
Qiuhong Qin;
Xiaojie Li;
Jiangang Yang;
Jibin Ma;
Jianping Ren

Publication type:

Article

Targeting Senescence, Oxidative Stress, and Inflammation: Quercetin-Based Strategies for Ocular Diseases in Older Adults.

Published in:

Clinical Interventions in Aging, 2025, v. 20, p. 791, doi. 10.2147/CIA.S516946

By:

Medoro, Alessandro;
Davinelli, Sergio;
Scuderi, Luca;
Scuderi, Gianluca;
Scapagnini, Giovanni;
Fragiotta, Serena

Publication type:

Article

Targeting aging pathways with natural compounds: a review of curcumin, epigallocatechin gallate, thymoquinone, and resveratrol.

Published in:

Immunity & Ageing, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12979-025-00522-y

By:

Ahmed, Mohamed

Publication type:

Article

Effects of low glucose microenvironment on the proliferation, migration and senescence of meniscus-derived stem cells.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-07642-x

By:

Tong, Jiabei;
Alzahrani, Badr;
Subbiah, Suresh Kumar;
Rampal, Sanjiv;
Ramasamy, Rajesh;
Ma, Zhijie;
Wu, Xiaoyun;
Mok, Pooi Ling

Publication type:

Article

Bridging aging, immunity, and atherosclerosis: novel insights into senescence-related genes.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1557266

By:

Lu, Yan;
Yuan, Rong;
Xin, Qiqi;
Chen, Keji;
Cong, Weihong

Publication type:

Article

Association between premature ovarian insufficiency and biological aging.

Published in:

European Journal of Endocrinology, 2025, v. 192, n. 6, p. 744, doi. 10.1093/ejendo/lvaf102

By:

Zhou, Jinting;
Fan, Menglin;
Lett, Aaron M;
Jin, Geling;
You, Qiqi;
Zeng, Jingjing;
Chen, Bo;
Wu, Yucen;
Xing, Hui;
Xu, Shaoyong

Publication type:

Article

Association of biological aging acceleration transitions and burdens with incident cardiovascular disease: longitudinal insights from a national cohort study.

Published in:

BMC Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12916-025-04177-w

By:

Zhang, Xin;
Yan, Yu;
Liu, Yuxin;
Wang, Zixin;
Jiang, Yuchen;
Zhang, Shuo;
Xu, Tongda;
Wang, Ke;
Zheng, Chu;
Zeng, Ping

Publication type:

Article

DNA methylation protects cancer cells against senescence.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61157-7

By:

Chen, Xiaoying;
Yamaguchi, Kosuke;
Rodgers, Brianna;
Goehrig, Delphine;
Vindrieux, David;
Lahaye, Xavier;
Nolot, Matthieu;
Ferry, Laure;
Lanciano, Sophie;
Martin, Nadine;
Dubus, Pierre;
Miura, Fumihito;
Ito, Takashi;
Cristofari, Gael;
Manel, Nicolas;
Kanemaki, Masato T.;
Bernard, David;
Defossez, Pierre-Antoine

Publication type:

Article

Lipoic acid functions in Paneth cells to prevent human intestinal stem cell aging.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61070-z

By:

Zhang, Zehong;
Wan, Qianyi;
Zhu, Yuedan;
Ye, Jinbao;
Fu, Fang;
Fan, Xinxin;
Chen, Haiou;
Ren, Gang;
Jiang, Wei;
Guo, Xiaoxin;
Zhou, Juanyu;
Yan, La;
Yan, Jinhua;
Liu, Xingzhu;
Yuan, Yu;
Chen, Yi;
Chen, Haiyang

Publication type:

Article

Recent advances in dermal fibroblast senescence and skin aging: unraveling mechanisms and pioneering therapeutic strategies.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1592596

By:

Nan, Li;
Guo, Pengchao;
Hui, Wang;
Xia, Fang;
Yi, Chenggang

Publication type:

Article

Oral Angiotensin-(1-7) formulation after established elastase-induced emphysema suppresses inflammation and restores lung architecture.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1540475

By:

Magalhaes, Giselle Santos;
Villacampa, Alicia;
Rodrigues-Machado, Maria Gloria;
Campagnole-Santos, Maria Jose;
Souza Santos, Robson Augusto;
Sánchez-Ferrer, Carlos F.;
Peiró, Concepción

Publication type:

Article

Telomere Length and Telomerase Activity as Biomarkers in the Diagnostics and Prognostics of Pathological Conditions.

Published in:

Biochemistry (00062979), 2025, v. 90, n. 6, p. 700, doi. 10.1134/S0006297925600814

By:

Moskaleva, Elizaveta Yu.;
Glukhov, Alexander I.;
Zhirnik, Alexander S.;
Vysotskaya, Olga V.;
Vorobiova, Svetlana A.

Publication type:

Article

Histopathological analysis of respiratory muscles in patients with acute COVID-19 infection.

Published in:

Cell & Tissue Research, 2025, v. 401, n. 1, p. 59, doi. 10.1007/s00441-025-03973-3

By:

Steingruber, Laura;
Handtke, Simona;
Schweiger, Franziska;
Schiele, Stefan;
Märkl, Bruno;
Koch, Marco

Publication type:

Article

Examination of Skeletal and Senescence Phenotypes in Young Mice with Juvenile Onset Type 1 Diabetes.

Published in:

Calcified Tissue International, 2025, v. 116, n. 1, p. 1, doi. 10.1007/s00223-025-01401-w

By:

Kaur, Japneet;
Brooks, Hannah W.;
Froemming, Mitchell N.;
Cusick, Nicholas C.;
Funk, Janet L.;
Farr, Joshua N.

Publication type:

Article

An Integrated Pathogenetic Model of Primary Biliary Cholangitis.

Published in:

Livers, 2025, v. 5, n. 2, p. 15, doi. 10.3390/livers5020015

By:

Kouroumalis, Elias;
Tsomidis, Ioannis;
Voumvouraki, Argyro

Publication type:

Article

Anti-senescence therapies: a new concept to address cardiovascular disease Open Access.

Published in:

Cardiovascular Research, 2025, v. 121, n. 5, p. 730, doi. 10.1093/cvr/cvaf030

By:

Stojanović, Stevan D;
Thum, Thomas;
Bauersachs, Johann

Publication type:

Article

Corneal oxidative stress, inflammation, and senescence as key drivers of ocular pathology in a chronic graft-versus-host disease model.

Published in:

BMC Ophthalmology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12886-025-04210-9

By:

Wu, Rong;
Liu, Shuwan;
Shen, Zhan;
Zhao, Yinghan;
Hong, Jing;
Ma, Jiao

Publication type:

Article

PSMA5 as a modulator of glioblastoma senescence and prognosis.

Published in:

BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-025-14441-0

By:

Yao, Jiahao;
Zhang, Hongyu;
Gu, Qiang;
Sun, Xiaoyang;
Li, Lang;
Wang, Xuefeng

Publication type:

Article

A High-Throughput and Robust Relative Potency Assay Measuring Human Cytomegalovirus Infection in Epithelial Cells for Vaccine Development.

Published in:

Vaccines, 2025, v. 13, n. 6, p. 626, doi. 10.3390/vaccines13060626

By:

Smiddy, Nicole M.;
Patel, Nisarg;
Troutman, Matthew C.;
Kearns, Kristine M.;
Davis, Zachary P.;
Adams, Christopher S.;
Hofmann, Carl;
Warakomski, Donald J.;
Davis, Harrison;
Spatafore, Daniel;
Kristopeit, Adam;
DePhillips, Pete;
Loughney, John W.

Publication type:

Article

Uric Acid Promotes Human Umbilical Vein Endothelial Cell Senescence In Vitro.

Published in:

Metabolites (2218-1989), 2025, v. 15, n. 6, p. 402, doi. 10.3390/metabo15060402

By:

Lewandowska, Katarzyna;
Mikuła-Pietrasik, Justyna;
Książek, Krzysztof;
Tykarski, Andrzej;
Uruski, Paweł

Publication type:

Article

Trophoblast Extracellular Vesicles as Modulators of Keratinocyte Stress Response and Senescence.

Published in:

Life (2075-1729), 2025, v. 15, n. 6, p. 918, doi. 10.3390/life15060918

By:

Nacka-Aleksić, Mirjana;
Pirković, Andrea;
Vilotić, Aleksandra;
Kosanović, Maja;
Dekanski, Dragana;
Legner, Janko;
Jovanović Krivokuća, Milica

Publication type:

Article

Exploring the differential functions of circulating follicular helper T and peripheral helper T cells in rheumatoid arthritis based on metabolism patterns.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1608675

By:

Bai, Ziran;
Yang, Siwen;
Ren, Jinyi;
Zhang, Cheng;
Chen, Xianmei;
Huang, Huina;
Wang, Guan;
Tang, Yawei;
Qi, Jingjing;
Li, Xia

Publication type:

Article

Correlation of senescence-related gene FEN1 on neuroblastoma progression and cisplatin chemotherapy sensitivity.

Published in:

Oncology Research, 2025, v. 33, n. 7, p. 1695, doi. 10.32604/or.2025.060021

By:

HU, YOUYANG;
LUO, YISHU;
XIE, TIANYUE;
CHEN, YUEHUA;
ZHAO, JUN;
JI, WEICHAO;
YAN, ZHIWEI;
QIU, SITONG;
GAO, KEXIN;
ZHU, HAIXIA;
MA, LIMIN;
YIN, QIYOU

Publication type:

Article

Preclinical Evidence That Mesoglycan Unfolds Complex Anti-Aging Effects in Photoaged Female Facial Skin.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5787, doi. 10.3390/ijms26125787

By:

Zeltzer, Assaf;
Keren, Aviad;
Paus, Ralf;
Gilhar, Amos

Publication type:

Article

Oxamate, an LDHA Inhibitor, Inhibits Stemness, Including EMT and High DNA Repair Ability, Induces Senescence, and Exhibits Radiosensitizing Effects in Glioblastoma Cells.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5710, doi. 10.3390/ijms26125710

By:

Hashimoto, Takuma;
Ushikubo, Go;
Arao, Naoya;
Hatabi, Khaled;
Tsubota, Kazuki;
Hosoi, Yoshio

Publication type:

Article

The Profile of Selected Protein Markers of Senescence in the Placentas of Cows During Early–Mid-Pregnancy and Parturition with and Without the Retention of Fetal Membranes: A Preliminary Study.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5475, doi. 10.3390/ijms26125475

By:

Kosztowny, Ewelina;
Wawrzykowski, Jacek T.;
Jamioł, Monika A.;
Kankofer, Marta

Publication type:

Article

In This Issue.

Published in:: Arthritis & Rheumatology, 2025, v. 77, n. 7, p. 1, doi. 10.1002/art.43281
Publication type:: Article

Immunometabolism and oxidative stress: roles and therapeutic strategies in cancer and aging.

Published in:

NPJ Aging, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41514-025-00250-z

By:

Zhou, Nan-jie;
Bao, Wei-Qian;
Zhang, Cui-fen;
Jiang, Meng-Lin;
Liang, Tu-Liang;
Ma, Gang-Yuan;
Liu, Liang;
Pan, Hu-Dan;
Li, Run-Ze

Publication type:

Article

Identification of markers for neurescence through transcriptomic profiling of postmortem human brains.

Published in:

NPJ Aging, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41514-025-00235-y

By:

Dehkordi, Shiva Kazempour;
Sajedi, Sogand;
Heshmat, Amirreza;
Orr, Miranda E.;
Zare, Habil

Publication type:

Article

Deciphering Biochemical and Molecular Insights into Proline Induced Mitigation of Postharvest Senescence in Hemerocallis lilioasphodelus L. Scapes.

Published in:

Russian Journal of Plant Physiology, 2025, v. 72, n. 4, p. 1, doi. 10.1134/S1021443725600394

By:

Lone, H. Y.;
Aftab, M.;
Tantray, W. W.;
Wani, A. A.;
Zargar, M. A.;
Tahir, I.

Publication type:

Article

Curcumin-Induced Apoptotic Cell Death in Human Glioma Cells Is Enhanced by Clusterin Deficiency.

Published in:

Pharmaceutics, 2025, v. 17, n. 6, p. 679, doi. 10.3390/pharmaceutics17060679

By:

Sultana, Pinky;
Novotny, Jiri

Publication type:

Article

Synergistic Effect of Banaba Leaf Extract and Policosanol (Raydel ®) Ameliorate High Cholesterol and High Galactose-Diet Induced Adverse Events in Zebrafish.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 860, doi. 10.3390/ph18060860

By:

Cho, Kyung-Hyun;
Lee, Sang Hyuk;
Lee, Yunki;
Bahuguna, Ashutosh;
Kim, Ji-Eun;
Djayanti, Krismala;
Jeon, Cheolmin

Publication type:

Article

Synergistic Autophagy-Related Mechanisms of Protection Against Brain Aging and AD: Cellular Pathways and Therapeutic Strategies.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 829, doi. 10.3390/ph18060829

By:

Cordos, Bogdan;
Tero-Vescan, Amelia;
Hampson, Ian N.;
Oliver, Anthony W.;
Slevin, Mark

Publication type:

Article

Dasatinib and Quercetin Combination Increased Kidney Damage in Acute Folic Acid-Induced Experimental Nephropathy.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 822, doi. 10.3390/ph18060822

By:

Battaglia-Vieni, Antonio;
Marchant, Vanessa;
Tejedor-Santamaria, Lucia;
García-Caballero, Cristina;
Flores-Salguero, Elena;
Ruiz-Torres, María Piedad;
Rayego-Mateos, Sandra;
Sanz, Ana Belen;
Ortiz, Alberto;
Ruiz-Ortega, Marta

Publication type:

Article

Influence of a Zombie-like State of the Liver on Drugs and Its Medico-Legal Implications: A Scoping Review.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 787, doi. 10.3390/ph18060787

By:

Šoša, Ivan

Publication type:

Article

SARS-CoV-2 (MA10) Infection Aggravates Cerebrovascular Pathology in Endothelial Nitric Oxide Synthase-Deficient Mice.

Published in:

Viruses (1999-4915), 2025, v. 17, n. 6, p. 784, doi. 10.3390/v17060784

By:

Ismael, Saifudeen;
Umar, Meenakshi;
Ouvrier, Blake;
Hall, Gregory;
Cummins, McKenzie;
Sapkota, Arjun;
Talkington, Grant;
White, Amanda Louise;
Milner, Richard;
Khismatullin, Damir B.;
Bix, Gregory

Publication type:

Article

The role of senescence in the pathogenesis and treatment of diabetic foot ulcers.

Published in:

Diabetic Foot Journal, 2020, v. 23, n. 3, p. 64

By:

Wilkinson, Holly N.;
Hardman, Matthew J.

Publication type:

Article

TGF-β1调控人肺泡上皮细胞中DNA甲基化酶和端粒酶的机制.

Published in:

Chinese Nursing Research, 2023, v. 37, n. 12, p. 2138, doi. 10.12102/j.issn.1009-6493.2023.12.010

By:

孙梓越;
钱力;
李丹;
朱瑞芳;
韩永康;
刘学军

Publication type:

Article

The hydra of anesthetic neurotoxicity: Myth or reality?

Published in:

2018

By:

Graham, Marjory Ruth

Publication type:

Editorial

A Senescence-Like Cell-Cycle Arrest Occurs During Megakaryocytic Maturation: Implications for Physiological and Pathological Megakaryocytic Proliferation.

Published in:

PLoS Biology, 2010, v. 8, n. 9, p. 1, doi. 10.1371/journal.pbio.1000476

By:

Besancenot, Rodolphe;
Chaligné, Ronan;
Tonetti, Carole;
Pasquier, Florence;
Marty, Caroline;
Lécluse, Yann;
Vainchenker, William;
Constantinescu, Stefan N.;
Giraudier, Stéphane

Publication type:

Article

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor.

Published in:

PLoS Biology, 2008, v. 6, n. 12, p. e301, doi. 10.1371/journal.pbio.0060301

By:

Coppé, Jean-Philippe;
Patil, Christopher K.;
Rodier, Francis;
Yu Sun;
Muñoz, Denise P.;
Goldstein, Joshua;
Nelson, Peter S.;
Desprez, Pierre-Yves;
Campisi, Judith

Publication type:

Article

Mechanisms of Aging in Bone Marrow Stem Cells.

Published in:

PLoS Biology, 2007, v. 5, n. 8, p. 1637, doi. 10.1371/journal.pbio.0050215

By:

Gross, Liza

Publication type:

Article

The Cell Nucleus and Aging: Tantalizing Clues and Hopeful Promises.

Published in:

PLoS Biology, 2005, v. 3, n. 11, p. 1, doi. 10.1371/journal.pbio.0030395

By:

Scaffidi, Paola;
Gordon, Leslie;
Misteli, Tom

Publication type:

Article

Cellular senescence in the pathogenesis of ovarian dysfunction.

Published in:

Journal of Obstetrics & Gynaecology Research, 2024, v. 50, n. 5, p. 800, doi. 10.1111/jog.15918

By:

Harada, Miyuki

Publication type:

Article

Dehydroepiandrosterone as a potential agent to slow down ovarian aging.

Published in:

Journal of Obstetrics & Gynaecology Research, 2017, v. 43, n. 12, p. 1855, doi. 10.1111/jog.13456

By:

Lin, Li‐Te;
Cheng, Jiin‐Tsuey;
Wang, Peng‐Hui;
Li, Chia‐Jung;
Tsui, Kuan‐Hao

Publication type:

Article

Telomere elongation via alternative lengthening of telomeres (ALT) and telomerase activation in primary metastatic medulloblastoma of childhood.

Published in:

Journal of Neuro-Oncology, 2019, v. 142, n. 3, p. 435, doi. 10.1007/s11060-019-03127-w

By:

Minasi, Simone;
Baldi, Caterina;
Pietsch, Torsten;
Donofrio, Vittoria;
Pollo, Bianca;
Antonelli, Manila;
Massimino, Maura;
Giangaspero, Felice;
Buttarelli, Francesca Romana

Publication type:

Article

The Cdk inhibitor flavopiridol enhances temozolomide-induced cytotoxicity in human glioma cells.

Published in:

Journal of Neuro-Oncology, 2013, v. 115, n. 2, p. 169, doi. 10.1007/s11060-013-1220-5

By:

Hayashi, Takuro;
Adachi, Kazuhide;
Ohba, Shigeo;
Hirose, Yuichi

Publication type:

Article

Preferential localization of γH2AX foci in euchromatin of retina rod cells after DNA damage induction.

Published in:

Chromosome Research, 2013, v. 21, n. 8, p. 789, doi. 10.1007/s10577-013-9395-3

By:

Lafon-Hughes, Laura;
Tomaso, María;
Liddle, Pablo;
Toledo, Andrea;
Reyes-Ábalos, Ana;
Folle, Gustavo

Publication type:

Article