Works about BCL-2 genes

Results: 630

Evaluation of polymorphism in BCL-2, PD-1, and PD-L1 genes in myelodysplastic neoplasms.

Published in:

Acta Haematologica Polonica, 2025, v. 56, n. 3, p. 222, doi. 10.5603/ahp.104373

By:

Kuszczak, Bartłomiej;
Łacina, Piotr;
Dratwa-Kuzmin, Marta;
Bogunia-Kubik, Katarzyna;
Wróbel, Tomasz;
Rybka, Justyna

Publication type:

Article

Somatic cell transfer of c- Myc and Bcl- 2 induces large-cell anaplastic medulloblastomas in mice.

Published in:

Journal of Neuro-Oncology, 2016, v. 126, n. 3, p. 415, doi. 10.1007/s11060-015-1985-9

By:

Jenkins, Noah;
Rao, Ganesh;
Eberhart, Charles;
Pedone, Carolyn;
Dubuc, Adrian;
Fults, Daniel

Publication type:

Article

Co-delivery of miRNA-15a and miRNA-16–1 using cationic PEGylated niosomes downregulates Bcl-2 and induces apoptosis in prostate cancer cells.

Published in:

Biotechnology Letters, 2021, v. 43, n. 5, p. 981, doi. 10.1007/s10529-021-03085-2

By:

Ghaffari, Maedeh;
Kalantar, Seyed Mehdi;
Hemati, Mahdie;
Dehghani Firoozabadi, Ali;
Asri, Amir;
Shams, Ali;
Jafari Ghalekohneh, Sina;
Haghiralsadat, Fateme

Publication type:

Article

PEX1 is a mediator of α1‐adrenergic signaling attenuating doxorubicin‐induced cardiotoxicity.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 11, p. 1, doi. 10.1002/jbt.23196

By:

Li, Wenjuan;
Xie, Huilin;
Hu, Huang;
Huang, Jihong;
Chen, Sun

Publication type:

Article

Novel insights into the potential mechanisms underlying carbendazim‐induced hepatorenal toxicity in rats.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 8, p. 1, doi. 10.1002/jbt.23079

By:

Ebedy, Yasmin A.;
Elshazly, Mohamed O.;
Hassan, Neven H.;
Ibrahim, Marwa A.;
Hassanen, Eman I.

Publication type:

Article

Novel boron‐containing compound, halogenated boroxine, induces selective cytotoxicity through apoptosis triggering in UT‐7 leukemia.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 5, p. 1, doi. 10.1002/jbt.23005

By:

Hadzic, Maida;
Pojskic, Lejla;
Lojo‐Kadric, Naida;
Haveric, Anja;
Ramic, Jasmin;
Galic, Borivoj;
Haveric, Sanin

Publication type:

Article

Eugenol–piperine loaded polyhydroxy butyrate/polyethylene glycol nanocomposite‐induced apoptosis and cell death in nasopharyngeal cancer (C666‐1) cells through the inhibition of the PI3K/AKT/mTOR signaling pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 4, p. 1, doi. 10.1002/jbt.22700

By:

Sun, Xiaopeng;
Veeraraghavan, Vishnu Priya;
Surapaneni, Krishna Mohan;
Hussain, Sardar;
Mathanmohun, Maghimaa;
Alharbi, Sulaiman Ali;
Aladresi, Aref Ali Mohammed;
Chinnathambi, Arunachalam

Publication type:

Article

Ferutinin: A phytoestrogen from ferula and its anticancer, antioxidant, and toxicity properties.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 4, p. 1, doi. 10.1002/jbt.22713

By:

Naji Reyhani Garmroudi, Shahrzad;
Karimi, Ehsan;
Oskoueian, Ehsan;
Homayouni‐Tabrizi, Masoud;
Iranshahi, Mehrdad

Publication type:

Article

Efficacy of Prunus armenica, Bee venom, and their combinations on p53 and Bcl-2 gene expression in human pancreatic and lung cancer cells.

Published in:

Umm Al-Qura University Journal of Applied Sciences (Springer Nature), 2023, v. 9, n. 4, p. 487, doi. 10.1007/s43994-023-00058-1

By:

Kadasah, Sultan F.;
Alrefaei, Abdulmajeed F.;
Ali, Harbi A.

Publication type:

Article

Comparison of the effects of C-KIT, MMP-2, Ki-67, Bcl-2 and metallothionein expression on prognostic factors in skin and non-skin malignant melanomas.

Published in:

Medicine Science, 2022, v. 11, n. 3, p. 953, doi. 10.5455/medscience.2021.05.174

By:

Eriten, Berna;
Goze, Fahrettin

Publication type:

Article

Synthesis, characterization and anticancer activity of novel hydrazide-hydrazones derived from ethyl paraben.

Published in:

Journal of Research in Pharmacy, 2020, v. 24, n. 3, p. 341, doi. 10.35333/jrp.2020.156

By:

HAN, M. İhsan;
ATALAY, Pınar;
İMAMOĞLU, Nalan;
KÜÇÜKGÜZEL, Ş. Güniz

Publication type:

Article

Exendin-4高活性短肽模拟物的筛选及生物活性.

Published in:

Journal of Jilin University (Science Edition) / Jilin Daxue Xuebao (Lixue Ban), 2019, v. 57, n. 3, p. 696, doi. 10.13413/j.cnki.jdxblxb.2018207

By:

宋相伟;
王雪丽;
王璐璐;
楼婉琳;
王丽萍;
熊新辉;
牛建丽;
李惟

Publication type:

Article

紫灵芝多糖改善运动疲劳小鼠学习记忆能力.

Published in:

Modern Food Science & Technology, 2025, v. 41, n. 5, p. 49, doi. 10.13982/j.mfst.1673-9078.2025.5.1321

By:

王冬枝;
马矜烁

Publication type:

Article

Cyanidin-3- O -Glucoside Mitigates Amyloid-Beta (1–42)-Induced Apoptosis in SH-SY5Y Cells by Regulating Ca 2+ Homeostasis and Inhibiting Mitochondrial Dysfunction.

Published in:

Antioxidants, 2025, v. 14, n. 4, p. 490, doi. 10.3390/antiox14040490

By:

Ma, Chao;
Nie, Yu;
Zhang, Donglei;
Ran, Lulu;
Xu, Su;
Ran, Xun;
Huang, Junya;
Meng, Lingshuai

Publication type:

Article

The effects of ATP sensitive potassium channel (KATP) opener and blockers on Bcl-2, Bax, and Cyt-c gene expression levels in epileptic rats.

Published in:

Journal of Experimental & Clinical Medicine / Deneysel ve Klinik Tip Dergisi, 2022, v. 39, n. 3, p. 857, doi. 10.52142/omujecm.39.3.50

By:

KILIÇ, Ümit;
SOYTÜRK, Hayriye

Publication type:

Article

Investigating the Synergism of Lactobacillus Plantarum Cell Lysate Supernatant and Carboplatin on the Induction of Cell Death and Expression of Bax and Bcl-2 Genes in the SK-OV-3 Cell Line.

Published in:

Biological Journal of Microorganism, 2024, v. 12, n. 48, p. 51, doi. 10.22108/bjm.2023.132367.1515

By:

samanarad, Zahra;
Sepahy, Abbas Akhavan;
Torbati, Maryam Bikhof

Publication type:

Article

The Effects of Native Lactobacillus Paracasei Supernatant Solution on Death of Pancreatic Adenocarcinoma Cells (AsPC-1) and Expression of bax, bcl2, and DPC4 Apoptotic Genes.

Published in:

Biological Journal of Microorganism, 2022, v. 10, n. 40, p. 1, doi. 10.22108/bjm.2020.120382.1251

By:

Yeganeh, Reihane;
Ebrahimi, Maryam Tajabadi;
Ramezani, Mina

Publication type:

Article

Investigating the cell proliferation and migration inhibition by cerium oxide nanoparticles loaded with doxorubicin in MDA-MB-231 cell line.

Published in:

Nanomedicine Journal, 2024, v. 11, n. 4, p. 426, doi. 10.22038/nmj.2024.74952.1820

By:

Mahdavi, Maryam;
Shahbazi, Shahrzad;
Reiisi, Somayeh;
Rigi, Garshasb

Publication type:

Article

The Effects of Lycopene and Insulin on Histological Changes and the Expression Level of Bcl-2 Family Genes in the Hippocampus of Streptozotocin-Induced Diabetic Rats.

Published in:

Journal of Diabetes Research, 2017, p. 1, doi. 10.1155/2017/4650939

By:

Soleymaninejad, Masoume;
Joursaraei, Seyed Gholamali;
Feizi, Farideh;
Anarkooli, Iraj Jafari

Publication type:

Article

Spectroscopic Studies Of 10-Pyrimidyl-3,6-Diazaphenothiazine With Anticancer Activity.

Published in:

Malaysian Journal of Medicine & Health Sciences, 2022, v. 18, p. 82

By:

Morak-Młodawska, Beata;
Maciążek-Jurczyk, Małgorzata;
Jeleń, Małgorzata;
Owczarzy, Aleksandra;
Rogóż, Wojciech;
Kulig, Karolina;
Martula, Emilia

Publication type:

Article

Ag/Au bimetallic nanoparticles induce apoptosis in human cancer cell lines via P53, CASPASE-3 and BAX/BCL-2 pathways.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2018, v. 46, p. S389, doi. 10.1080/21691401.2018.1495645

By:

Katifelis, Hector;
Lyberopoulou, Anna;
Mukha, Iuliia;
Vityuk, Nadiia;
Grodzyuk, Gallina;
Theodoropoulos, George E.;
Efstathopoulos, Efstathios P.;
Gazouli, Maria

Publication type:

Article

Taurine exhibits antioxidant, anti-inflammatory, and antiapoptotic effects against pyraclostrobin exposure in rats.

Published in:

Toxicology Research, 2024, v. 13, n. 4, p. 1, doi. 10.1093/toxres/tfae120

By:

Serim, Ibrahim;
Demirel, Hasan Huseyin;
Zemheri-Navruz, Fahriye;
Ince, Sinan

Publication type:

Article

Vincamine induces cytoprotective autophagy via regulation of ampk/mtor signaling pathway in gentamicin-induced hepatotoxicity and nephrotoxicity in rats.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-06355-5

By:

Abouelhamd, Alaa;
Shehata, Nourhan Elpry Mahmoud;
Abdel-Hafez, Sara Mohamed Naguib;
Abu-Baih, Dalia H.

Publication type:

Article

Functional role of the flexible N-terminal extension of FKBP38 in catalysis.

Published in:

Scientific Reports, 2013, p. 1, doi. 10.1038/srep02985

By:

CongBao Kang;
Hong Ye;
Joel Chia;
Bo-Hwa Choi;
Dhe-Paganon, Sirano;
Simon, Bernd;
Schütz, Ulrike;
Sattler, Michael;
Ho Sup Yoon

Publication type:

Article

Cytotoxic and apoptotic potential of gemini-chrysophanol nanoparticles against human colorectal cancer HCT-116 cell lines.

Published in:

BMC Pharmacology & Toxicology, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s40360-022-00597-z

By:

Naqishbandi, Alaadin M.

Publication type:

Article

The inhibitory role of stigmasterol on tumor growth by inducing apoptosis in Balb/c mouse with spontaneous breast tumor (SMMT).

Published in:

BMC Pharmacology & Toxicology, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s40360-022-00578-2

By:

AmeliMojarad, Mandana;
AmeliMojarad, Melika;
Pourmahdian, Alireza

Publication type:

Article

Effects of Centella asiatica L. On Spatial Memory and Bcl-2 Gene Expression in the Hippocampus of Rats Injected With Trimethyltin.

Published in:

Indonesian Journal of Pharmacy / Majalah Farmasi Indonesia, 2021, v. 32, n. 2, p. 141

By:

Yuliani, Sapto;
Akbar, Muhammad Faishal;
Rochmafihro, Nurfidho;
Uthary, Yosi;
Deslaila, Lasmi

Publication type:

Article

Berberis vulgaris fruit extract mitigated apoptosis in experimentally induced testicular ischemia and reperfusion injury in rats.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1514676

By:

Yigit, Serdar;
Akgun, Sakir;
Yesilyurt, Isa;
Bitiktas, Soner;
Taskin, Ergin;
Alper Kahraman, Ali;
Yayla, Muhammed;
Kilicle, Pınar Aksu;
Ali Bingol, Seyit;
Ozdemir, Bengul;
Akdogan, Gül Esma;
Karagöz, Mehmet Ali

Publication type:

Article

Berberis vulgaris fruit extract mitigated apoptosis in experimentally induced testicular ischemia and reperfusion injury in rats.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1514676

By:

Yigit, Serdar;
Akgun, Sakir;
Yesilyurt, Isa;
Bitiktas, Soner;
Taskin, Ergin;
Alper Kahraman, Ali;
Yayla, Muhammed;
Kilicle, Pınar Aksu;
Ali Bingol, Seyit;
Ozdemir, Bengul;
Akdogan, Gül Esma;
Karagöz, Mehmet Ali

Publication type:

Article

α-Bisabolol alleviates doxorubicin-induced cognitive dysfunction in rats via enhancing the hippocampal BDNF/TrKB signaling and inhibiting neuroinflammation.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1549009

By:

Elazab, Sara T.;
Hsu, Walter H.

Publication type:

Article

Sinensetin attenuates hepatic ischemia-reperfusion injury through suppressing GRP78/CHOP-mediated endoplasmic reticulum (ER) stress in mice.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1519497

By:

Yang, Yihong;
Xiong, Guanghua;
Shi, Huangqi;
Peng, Yulin;
Liu, Jinghong;
Jiang, Yaxuan;
Lu, Min;
Liu, Hongbo;
Liu, Yong

Publication type:

Article

Dysregulation of Cell Survival in Diffuse Large B Cell Lymphoma: Mechanisms and Therapeutic Targets.

Published in:

Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00107

By:

Miao, Yi;
Medeiros, L. Jeffrey;
Xu-Monette, Zijun Y.;
Li, Jianyong;
Young, Ken H.

Publication type:

Article

Ameliorative Effect of Melatonin Against Reproductive Toxicity of Tramadol in Rats via the Regulation of Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis-related Gene Expression Signaling Pathway.

Published in:

Addiction & Health, 2020, v. 12, n. 2, p. 118, doi. 10.22122/ahj.v12i2.265

By:

Koohsari, Motahareh;
Ahangar, Nematollah;
Mohammadi, Ebrahim;
Shaki, Fatemeh

Publication type:

Article

Corilagin induces apoptosis and autophagy in NRF2-addicted U251 glioma cell line.

Published in:

Molecular Medicine Reports, 2021, v. 23, n. 5, p. N.PAG

By:

Liu, Jilan;
Qin, Xianyun;
Ma, Wenyuan;
Jia, Shu;
Zhang, Xiaobei;
Yang, Xinlin;
Pan, Dongfeng;
Jin, Feng

Publication type:

Article

Silencing of long-chain non-coding RNA GAS5 in osteoarthritic chondrocytes is mediated by targeting the miR-34a/Bcl-2 axis.

Published in:

Molecular Medicine Reports, 2020, v. 21, n. 3, p. 1310, doi. 10.3892/mmr.2019.10900

By:

Ji, Qinghui;
Qiao, Xiaofeng;
Liu, Yongxiang;
Wang, Dawei;
Yan, Jinglong

Publication type:

Article

Sam68 mediates high glucose-induced podocyte apoptosis through modulation of Bax/Bcl-2.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3728, doi. 10.3892/mmr.2019.10601

By:

Chen, Yuyu;
Zhang, Li;
Liu, Shuangxin;
Yao, Binfeng;
Zhang, Hong;
Liang, Shun;
Ma, Jianchao;
Liang, Xinling;
Shi, Wei

Publication type:

Article

MicroRNA-421 promotes the progression of non-small cell lung cancer by targeting HOPX and regulating the Wnt/β-catenin signaling pathway.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 1, p. 151, doi. 10.3892/mmr.2019.10226

By:

Liang, Huagang;
Wang, Chao;
Gao, Kun;
Li, Jian;
Jia, Rui

Publication type:

Article

Investigation of the neuroprotective effects of a novel synthetic compound via the mitochondrial pathway.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 2, p. 1133, doi. 10.3892/mmr.2017.6745

By:

DI WANG;
SHUANG HU;
JUNRONG ZHANG;
QIUYUE LI;
XINYU LIU;
YU LI

Publication type:

Article

Apigenin inhibits glioma cell growth through promoting microRNA-16 and suppression of BCL-2 and nuclear factor-κB/MMP-9.

Published in:

Molecular Medicine Reports, 2016, v. 14, n. 3, p. 2352, doi. 10.3892/mmr.2016.5460

By:

XIN-JUN CHEN;
MIAN-YUN WU;
DENG-HUI LI;
JIN YOU

Publication type:

Article

Glucagon-like peptide-1 protects cardiomyocytes from advanced oxidation protein product-induced apoptosis via the PI3K/Akt/Bad signaling pathway.

Published in:

Molecular Medicine Reports, 2016, v. 13, n. 2, p. 1593, doi. 10.3892/mmr.2015.4724

By:

HUA ZHANG;
ZHOUYI XIONG;
JIAO WANG;
SHUANGSHUANG ZHANG;
LEI LEI;
LI YANG;
ZHEN ZHANG

Publication type:

Article

Curcumin enhances the antitumor effect of ABT-737 via activation of the ROS-ASK1-JNK pathway in hepatocellular carcinoma cells.

Published in:

Molecular Medicine Reports, 2016, v. 13, n. 2, p. 1570, doi. 10.3892/mmr.2015.4715

By:

RUINIAN ZHENG;
ZHIJIAN YOU;
JUN JIA;
SHUNHUAN LIN;
SHUAI HAN;
AIXUE LIU;
HUIDONG LONG;
SENMING WANG

Publication type:

Article

Dodecyl gallate induces apoptosis by upregulating the caspase-dependent apoptotic pathway and inhibiting the expression of anti-apoptotic Bcl-2 family proteins in human osteosarcoma cells.

Published in:

Molecular Medicine Reports, 2016, v. 13, n. 2, p. 1495, doi. 10.3892/mmr.2015.4717

By:

CHUN-HSIANG CHENG;
YEN-PO CHENG;
ING-LIN CHANG;
HSIN-YAO CHEN;
CHIA-CHIEH WU;
CHEN-PU HSIEH

Publication type:

Article

Reduced proliferation and increased apoptosis of the SGC-7901 gastric cancer cell line on exposure to GDC-0449.

Published in:

Molecular Medicine Reports, 2016, v. 13, n. 2, p. 1434, doi. 10.3892/mmr.2015.4677

By:

CHUANQING WU;
JI CHENG;
SHAOBO HU;
RUI DENG;
YAMBA WILLY MUANGU;
LIANG SHI;
KE WU;
PENG ZHANG;
WEILONG CHANG;
GUOBIN WANG;
KAIXIONG TAO

Publication type:

Article

Sodium formate induces autophagy and apoptosis via the JNK signaling pathway of photoreceptor cells.

Published in:

Molecular Medicine Reports, 2016, v. 13, n. 2, p. 1111, doi. 10.3892/mmr.2015.4675

By:

YING WANG;
SHAO-LIN XU;
WEN-JING XU;
HAI-YAN YANG;
PING HU;
YU-XIN LI

Publication type:

Article

AT1R blocker losartan attenuates intestinal epithelial cell apoptosis in a mouse model of Crohn's disease.

Published in:

Molecular Medicine Reports, 2016, v. 13, n. 2, p. 1156, doi. 10.3892/mmr.2015.4686

By:

TIAN-JING LIU;
YONG-YAN SHI;
EN-BO WANG;
TONG ZHU;
QUN ZHAO

Publication type:

Article

Neutrophil elastase and its therapeutic effect on leukemia cells.

Published in:

Molecular Medicine Reports, 2015, v. 12, n. 3, p. 4165, doi. 10.3892/mmr.2015.3946

By:

KAI-LING JIANG;
PENG-PENG MA;
XIAO-QUN YANG;
LIANG ZHONG;
HUI WANG;
XIN-YU ZHU;
BEI-ZHONG LIU

Publication type:

Article

Rg1 exhibits neuroprotective effects by inhibiting the endoplasmic reticulum stress-mediated c-Jun N-terminal protein kinase apoptotic pathway in a rat model of Alzheimer's disease.

Published in:

Molecular Medicine Reports, 2015, v. 12, n. 3, p. 3862, doi. 10.3892/mmr.2015.3853

By:

JUN-SHAN MU;
HANG LIN;
JIAN-XIN YE;
MIN LIN;
XIAO-PING CUI

Publication type:

Article

Ginsenoside Rg3 induces apoptosis in human multiple myeloma cells via the activation of Bcl-2-associated X protein.

Published in:

Molecular Medicine Reports, 2015, v. 12, n. 3, p. 3557, doi. 10.3892/mmr.2015.3802

By:

YUN LUO;
PING ZHANG;
HAN-QING ZENG;
SHI-FENG LOU;
DAO-XIN WANG

Publication type:

Article

Sanguinarine inhibits angiotensin II-induced apoptosis in H9c2 cardiac cells via restoring reactive oxygen species-mediated decreases in the mitochondrial membrane potential.

Published in:

Molecular Medicine Reports, 2015, v. 12, n. 3, p. 3400, doi. 10.3892/mmr.2015.3841

By:

YUAN LIU;
RONG JIAO;
ZHEN-GUO MA;
WEI LIU;
QING-QING WU;
ZHENG YANG;
FANG-FANG LI;
YUAN YUAN;
ZHOU-YAN BIAN;
QI-ZHU TANG

Publication type:

Article

One-dimensional copper oxide nanorods with potential anticancer effects against melanoma cells.

Published in:

Arabian Journal of Chemistry, 2024, v. 17, n. 4, p. N.PAG, doi. 10.1016/j.arabjc.2024.105689

By:

Zuo, Chenchen;
Fan, Pengju;
Hu, Chengjun;
Bu, Xin

Publication type:

Article