Works matching DE "ALZHEIMER'S disease"

Results: 5000

Gut microbiota-driven neuroinflammation in Alzheimer's disease: from mechanisms to therapeutic opportunities.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1582119

By:

Lei, Wenhui;
Cheng, Yiwen;
Liu, Xia;
Gao, Jie;
Zhu, Zhangcheng;
Ding, Wenwen;
Xu, Xiaocui;
Li, Yating;
Ling, Zongxin;
Jiang, Ruilai;
Chen, Xiaoying

Publication type:

Article

Integrative bioinformatics and machine learning approaches reveal oxidative stress and glucose metabolism related genes as therapeutic targets and drug candidates in Alzheimer's disease.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1572468

By:

Noor, Fatima;
Aslam, Sidra;
Piras, Ignazio S.;
Tremblay, Cecilia;
Beach, Thomas G.;
Serrano, Geidy E.

Publication type:

Article

Selective TRPC6 Modulator, C20, Improves Cognitive but Not Motor Function in a 5xFAD Mouse Model of Alzheimer's Disease.

Published in:

Journal of Evolutionary Biochemistry & Physiology, 2025, v. 61, n. 3, p. 926, doi. 10.1134/S0022093025030196

By:

Zernov, N.;
Меlenteva, D. M.;
Popugaeva, Е. А.

Publication type:

Article

P.006 Cost-effectiveness of Lecanemab for the treatment of early Alzheimer's Disease: a Canadian societal perspective.

Published in:

2025

By:

Burn, O;
Trueman, D;
Molloy, K;
Haynes, AE;
Castellano, K;
Pastor, L;
Wong, E;
Rothwell, S;
Jang, S;
Bodnar, C

Publication type:

Abstract

P.005 Real-world evidence of Lecanemab use in the United Statese.

Published in:

2025

By:

Zhao, C;
Brixner, DI;
Nair, KV;
Toyosaki, H;
Frech, FH;
Rosenbloom, MH

Publication type:

Abstract

P.003 Assessing the impact of attitudes toward aging on cognition and Alzheimer's Disease biomarkers in older adults.

Published in:

2025

By:

Otaner, F;
Walker, CS;
Noriega de la Colina, A;
Li, L;
Boulanger, C;
Thovinakere, N;
Noly-Gandon, A;
Barnoin, G;
Bennett, M;
Caplan, J;
Côté, L;
Elbaz, S;
Fock Ka Bao, S;
Kara, R;
Lavoie, N;
Nguyen, M;
Pallett-Wiesel, H;
Piché, JV;
Powers, A;
Ricciardelli, S

Publication type:

Abstract

P.002 Comprehensive validation of two commercial immunoassays for the biological diagnosis of Alzheimer's Disease a laboratory diagnostic test.

Published in:

2025

By:

Mammel, A;
Hsiung, G;
Kumar, P;
Mousavi, A;
Mackenzie, I;
Hirsch-Reinshagen, V;
Encarnacion, M;
Hallett, K;
Gil, P;
Frykman, H

Publication type:

Abstract

A.2 Cognitive outcomes of deep brain stimulation depend upon subiculum connectivity.

Published in:

2025

By:

Howard, C;
Reich, M;
Lou, L;
Pacheco-Barrios, N;
Alterman, R;
Rios, A;
Guo, M;
Luo, Z;
Friedrich, H;
Pines, A;
Montaser-Kouhsari, L;
Drew, W;
Hart, L;
Meyer, G;
Rajamani, N;
Friedrich, M;
Hollanda, V;
Lozano, A;
Picht, T;
Faust, K

Publication type:

Abstract

GR.4 EEG biomarkers for Alzheimer's Disease: a novel automated pipeline for detecting and monitoring disease progression.

Published in:

2025

By:

Simmatis, LE;
Russo, E;
Steininger, T;
Riddell, H;
Chen, E;
Chiu, Q;
Oh, D;
Taheri, P;
Harmsen, I;
Samuel, N

Publication type:

Abstract

Global Prevalence, Incidence, and Factors Influencing Falls in Older Adults With Dementia: Implications for Nursing and Healthy Aging.

Published in:

Journal of Nursing Scholarship, 2025, v. 57, n. 4, p. 678, doi. 10.1111/jnu.70012

By:

Octary, Tiara;
Sung, Chien‐Mei;
Chen, Ruey;
Chiang, Kai‐Jo;
Lee, Chiu‐Kuei;
Arifin, Hidayat;
Banda, Kondwani Joseph;
Chou, Kuei‐Ru

Publication type:

Article

Comparing Two Connected Speech Tasks in Greek Speakers With the Logopenic Variant of Primary Progressive Aphasia and Alzheimer's Disease.

Published in:

American Journal of Speech-Language Pathology, 2025, v. 34, n. 4, p. 2141, doi. 10.1044/2025_AJSLP-23-00474

By:

Karpathiou, Nomiki;
Kambanaros, Maria

Publication type:

Article

A single-snapshot inverse solver for two-species graph model of tau pathology spreading in human Alzheimer's disease.

Published in:

Brain Informatics, 2025, v. 12, n. 1, p. 1, doi. 10.1186/s40708-025-00264-z

By:

Wen, Zheyu;
Ghafouri, Ali;
Biros, George

Publication type:

Article

Deep ensemble learning with transformer models for enhanced Alzheimer's disease detection.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-08362-y

By:

Latif, Shiza;
Islam, Naeem Ul;
Uddin, Zaki;
Cheema, Khalid Mehmood;
Ahmed, Syed Sohail;
Khan, Muhammad Farhan

Publication type:

Article

Whole-genome sequencing shows modulation of neurodegenerative genes by Withania somnifera in human SK-N-SH cells.

Published in:

Frontiers in Molecular Neuroscience, 2025, p. 1, doi. 10.3389/fnmol.2025.1512727

By:

Sharma, Eshita;
Mehta, Dilip;
Jadhav, Nikita;
Gujrati, Gunjan;
Dhananya, S.;
Moorthy, Manju;
Ramaswamy, Gopalakrishna;
Zhou, Yundong;
Nair, Sujit

Publication type:

Article

The role of probiotics, prebiotics, and postbiotics: cellular and molecular pathways activated on glial cells in Alzheimer's disease.

Published in:

Frontiers in Neuroscience, 2025, p. 1, doi. 10.3389/fnins.2025.1598011

By:

Patricio-Martínez, Aleidy;
Patricio, Felipe;
Macuil-Chapuli, Edgar;
Martínez-Juárez, Enoc Álvaro;
Flores-Díaz, Steven;
Cedillo-Ramírez, María Lilia;
Limón, Ilhuicamina Daniel

Publication type:

Article

Gut Microbiome rewiring via fecal transplants: Uncovering therapeutic avenues in Alzheimer's disease models.

Published in:

BMC Neuroscience, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12868-025-00953-9

By:

Upadhyay, Prabhat;
Kumar, Sudhir;
Tyagi, Anurag;
Tyagi, Aayush Raj;
Barbhuyan, Tarun;
Gupta, Sarika

Publication type:

Article

Two cases of Amyloid-Related Imaging Abnormalities (ARIA) following lecanemab treatment for alzheimer's disease and a literature review.

Published in:

BMC Neurology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12883-025-04302-5

By:

Wang, Yingte;
Yu, Qun;
Chen, Bin;
Zhou, Jing;
Li, Zhiming;
Liao, Wang;
Liu, Jun;
Yang, Airong

Publication type:

Article

Multi-dimensional sleep health and dementia risk: a prospective study in the UK Biobank.

Published in:

BMC Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12916-025-04251-3

By:

Huang, Tianyi;
Beydoun, May A.;
Kianersi, Sina;
Redline, Susan;
Launer, Lenore J.

Publication type:

Article

Risk of dementia in older patients with different anesthesia: a systematic review and meta-analysis of cohort studies.

Published in:

BMC Geriatrics, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12877-025-06096-0

By:

Yang, Xixi;
Wang, Yan;
Qian, Fang;
lu, lili;
Bi, DongJun;
Tung, Tao-Hsin

Publication type:

Article

Characteristics of patients with idiopathic normal pressure hydrocephalus for whom neurosurgeons hesitate to perform shunt surgery: a nationwide hospital-based survey in Japan.

Published in:

Fluids & Barriers of the CNS, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12987-025-00681-6

By:

Kawai, Ryo;
Kazui, Hiroaki;
Ueba, Tetsuya;
Nakamura, Natsuko;
Minami, Marina;
Nakajima, Madoka;
Yamada, Shigeki;
Kishima, Haruhiko;
Kanemoto, Hideki;
Iseki, Chifumi;
Mori, Etsuro

Publication type:

Article

Evaluating the safety and feasibility of remote ischemic conditioning for slowing cognitive decline in mild Alzheimer's dementia.

Published in:

Frontiers in Neurology, 2025, p. 1, doi. 10.3389/fneur.2025.1592829

By:

Huang, Xin;
Ji, Qiling;
Tong, Tanna;
Cai, Lipeng;
Elmadhoun, Omar;
Zeng, Yanfang;
Geng, Xiaokun;
Ding, Yuchuan

Publication type:

Article

Diversity of Aβ aggregates produced in a gut-based Drosophila model of Alzheimer's disease.

Published in:

PLoS ONE, 2025, v. 20, n. 7, p. 1, doi. 10.1371/journal.pone.0314832

By:

Elovsson, Greta;
Klingstedt, Therése;
Nilsson, K. Peter R.;
Brorsson, Ann-Christin

Publication type:

Article

MicroRNA let-7f protects against H2O2-induced oxidative damage in neuroblastoma cells by targeting AKT-2.

Published in:

Archives of Medical Science, 2025, v. 21, n. 2, p. 648, doi. 10.5114/aoms.2020.94490

By:

Kuo Li;
Zhan-Qiang Wang;
Jun-Ling Zhang;
Pei-Yuan Lv

Publication type:

Article

Celastrol attenuates Alzheimer's disease-mediated learning and memory impairment by inhibiting endoplasmic reticulum stress-induced inflammation and oxidative stress.

Published in:

Archives of Medical Science, 2025, v. 21, n. 2, p. 538, doi. 10.5114/aoms/189906

By:

Fanfan Cao;
Limin Xu;
Xiaoxue He;
Yongbin Chi;
Ying Wang;
Qiuyun Liu;
Denghai Zhang

Publication type:

Article

Molecular Mechanisms of Perivascular Macrophages in Alzheimer's Disease: Insights from Single-Cell Sequencing and Mendelian Randomization.

Published in:

Cellular & Molecular Neurobiology, 2025, v. 45, n. 1, p. 1, doi. 10.1007/s10571-025-01590-w

By:

Zhang, Min;
Liu, Shufang;
Zhao, Yanan;
Wu, Ping;
Tian, Shouyuan;
Wu, Zhifang;
Li, Sijin

Publication type:

Article

GSK3β Substrate-competitive Inhibitors Regulate the gut Homeostasis and Barrier Function to Inhibit Neuroinflammation in Scopolamine-induced Alzheimer's Disease Model Mice.

Published in:

Inflammation, 2025, v. 48, n. 3, p. 1438, doi. 10.1007/s10753-024-02133-z

By:

Zhang, Lingyu;
Jiang, Zhihao;
Hu, Shaozhen;
Ni, Haojie;
Zhao, Yijing;
Tan, Xiaoqin;
Lang, Yi;
Na, Risong;
Li, Yanwu;
Du, Qun;
Li, Qing X;
Dong, Yan

Publication type:

Article

FoxO1 Alleviates the Mitochondrial ROS Levels Induced by α-Synuclein Preformed Fibrils in BV-2 Microglial Cells.

Published in:

Inflammation, 2025, v. 48, n. 3, p. 1300, doi. 10.1007/s10753-024-02119-x

By:

Na, Jiyeon;
Ryu, Hye Guk;
Park, Haeun;
Park, Hyeonwoo;
Lee, Eunmin;
Nam, Younwoo;
Kim, Hyerynn;
Jang, Sang-Min;
Kim, Do-Yeon;
Kim, Sangjune

Publication type:

Article

Alzheimer model chip with microglia BV2 cells.

Published in:

Microsystems & Nanoengineering, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41378-024-00862-7

By:

Yazdanpanah Moghadam, Ehsan;
Sonenberg, Nahum;
Packirisamy, Muthukumaran

Publication type:

Article

Associations of cardiometabolic multimorbidity with all-cause dementia, alzheimer's disease, and vascular dementia: a cohort study in the UK biobank.

Published in:

BMC Public Health, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12889-025-23352-5

By:

Zhang, Junrun;
Huang, Xiaxuan;
Ling, Yitong;
Xie, Xiaomei;
Zeng, Xiuli;
Lyu, Jun;
Huang, Li'an

Publication type:

Article

Predicting brain amyloid load with digital and blood-based biomarkers.

Published in:

Alzheimer's Research & Therapy, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13195-025-01801-y

By:

Chen, Weineng;
Liao, Yu;
Shi, Xinchong;
Su, Fengjuan;
Kong, Haifan;
Fang, Yingying;
Zheng, Yifan;
Zhou, Jiayi;
Liu, Ganqiang;
Zhou, Xianbo;
Yao, Xiaoli;
Ashford, Curtis B.;
Li, Feng;
Yang, Long;
Bergeron, Michael F.;
Ashford, J. Wesson;
Zhang, Xiangsong;
Pei, Zhong

Publication type:

Article

Prospective evaluation of plasma pTau217 stability for the detection of Alzheimer's disease in a tertiary memory clinic.

Published in:

Alzheimer's Research & Therapy, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13195-025-01779-7

By:

Arranz, Javier;
Ferrer, Rosa;
Zhu, Nuole;
Rubio-Guerra, Sara;
Rodríguez-Baz, Íñigo;
Arriola-Infante, José Enrique;
Maure-Blesa, Lucía;
Garcia-Castro, Jesús;
Selma-González, Judit;
Carmona-Iragui, María;
Barroeta, Isabel;
Illán-Gala, Ignacio;
Santos-Santos, Miguel;
Fortea, Juan;
Lleó, Alberto;
Tondo, Mireia;
Alcolea, Daniel

Publication type:

Article

Rescue of protein dyshomeostasis in hippocampal astrocytes from an Alzheimer's disease mouse model by stabilizing ER-mitochondrial interactions at a 20 nm distance.

Published in:

Alzheimer's Research & Therapy, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13195-025-01793-9

By:

Dematteis, Giulia;
Gong, Chunmei;
Malecka, Justyna;
Tonelli, Elisa;
Genazzani, Armando;
Tapella, Laura;
Eleuteri, Anna Maria;
Lim, Dmitry;
Bonfili, Laura

Publication type:

Article

Low-dose interleukin-2 in patients with mild to moderate Alzheimer's disease: a randomized clinical trial.

Published in:

Alzheimer's Research & Therapy, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13195-025-01791-x

By:

Faridar, Alireza;
Gamez, Nazaret;
Li, Daling;
Wang, Yanling;
Boradia, Reena;
Thome, Aaron D.;
Zhao, Weihua;
Beers, David R.;
Thonhoff, Jason R.;
Nakawah, Mohammad O.;
Román, Gustavo C.;
Volpi, John J.;
Toledo, Jon B.;
George, Michael;
Davis, Charles S.;
Pascual, Belen;
Grundman, Michael;
Masdeu, Joseph C.;
Appel, Stanley H.

Publication type:

Article

Machine-learning based strategy identifies a robust protein biomarker panel for Alzheimer's disease in cerebrospinal fluid.

Published in:

Alzheimer's Research & Therapy, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13195-025-01789-5

By:

Hou, Xiaosen;
Qiu, Yunjie;
Li, Hui;
Yan, Yan;
Zhao, Dongxu;
Ji, Simei;
Ni, Junjun;
Zhang, Jun;
Liu, Kefu;
Qing, Hong;
Quan, Zhenzhen

Publication type:

Article

Utilizing machine learning algorithms to identify biomarkers associated with Alzheimer's disease and ferroptosis-related genes.

Published in:

Technology & Health Care, 2025, v. 33, n. 4, p. 2041, doi. 10.1177/09287329251322278

By:

Wang, Di;
Lin, Chunsheng;
Liu, Gang;
Wang, Xin;
Han, Shengwang;
Han, Zengxin

Publication type:

Article

Glial phagocytosis for synapse and toxic proteins in neurodegenerative diseases.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00870-9

By:

Choi, Yeseong;
Chung, Won-Suk

Publication type:

Article

Structure-based discovery of forsythoside A as an effective inhibitor to reduce the neurotoxicity of amyloid β.

Published in:

Communications Chemistry, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42004-025-01587-y

By:

Bai, Si-Cong;
Wang, Ye-Cheng;
Ye, Wei-Lin;
Wu, Sheng-Yen;
Jia, Lee;
Hong, Liu;
Xie, Huan-Zhang;
Li, Gao

Publication type:

Article

Unveiling the therapeutic potential of natural products in Alzheimer's disease: insights from in vitro , in vivo , and clinical studies.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1601712

By:

Aktary, Nahida;
Jeong, Yerim;
Oh, Seungji;
Shin, Yeju;
Sung, Yoonsoo;
Rahman, Muntajin;
Ramos Santiago, Livia;
Choi, Jinwon;
Song, Han Gyeul;
Nurkolis, Fahrul;
Ribeiro, Rosy Iara Maciel Azambuja;
Park, Moon Nyeo;
Kim, Bonglee

Publication type:

Article

"Risk of Dementia in Non‐Overtly Functional Adrenal Tumour (NOFAT)".

Published in:

2025

By:

Notarianni, Elena

Publication type:

Letter to the Editor

Risk of Dementia in Non‐Overtly Functional Adrenal Tumours (NOFAT)—Reply.

Published in:

2025

By:

Mirzaei, Hadis;
Patrova, Jekaterina;
Mannheimer, Buster;
Lindh, Jonatan D.;
Falhammar, Henrik

Publication type:

Letter to the Editor

Regional Brain Metabolism across the Alzheimer's Disease Continuum in Down Syndrome.

Published in:

Annals of Neurology, 2025, v. 98, n. 1, p. 163, doi. 10.1002/ana.27226

By:

Arriola‐Infante, José Enrique;
Morcillo‐Nieto, Alejandra O.;
Zsadanyi, Sara E.;
Franquesa‐Mullerat, María;
Vaqué‐Alcázar, Lídia;
Rozalem‐Aranha, Mateus;
Arranz, Javier;
Rodríguez‐Baz, Íñigo;
Maure‐Blesa, Lucia;
Videla, Laura;
Barroeta, Isabel;
Del Hoyo Soriano, Laura;
Benejam, Bessy;
Fernández, Susana;
Sanjuan‐Hernández, Aida;
Giménez, Sandra;
Alcolea, Daniel;
Belbin, Olivia;
Flotats, Albert;
Camacho, Valle

Publication type:

Article

Neuropathological Evidence of Reduced Amyloid Beta and Neurofibrillary Tangles in Multiple Sclerosis Cortex.

Published in:

Annals of Neurology, 2025, v. 97, n. 6, p. 1067, doi. 10.1002/ana.27231

By:

Pansieri, J.;
Pisa, M.;
Yee, S.;
Gutnikova, A.;
Ridgeon, E.;
Hickman, R.;
Spencer, J.I.;
Esiri, M.M.;
DeLuca, G.C.

Publication type:

Article

The Use of Antihypertensive Medication and In Vivo Alzheimer's Disease Pathology.

Published in:

Annals of Neurology, 2025, v. 97, n. 6, p. 1051, doi. 10.1002/ana.27204

By:

Keum, Musung;
Byun, Min Soo;
Yi, Dahyun;
Ahn, Hyejin;
Jung, Gijung;
Jung, Joon Hyung;
Kong, Nayeong;
Lee, Jun‐Young;
Kim, Yu Kyeong;
Lee, Yun‐Sang;
Kang, Koung Mi;
Sohn, Chul‐Ho;
Lee, Dong Young;
Mook‐Jung, Inhee;
Choi, Murim;
Lee, Yu Jin;
Hahn, Seokyung;
Kim, Hyun Jung;
Young, Mun;
Chang

Publication type:

Article

Neuroimaging Predictors of Cognitive Resilience against Alzheimer's Disease Pathology.

Published in:

Annals of Neurology, 2025, v. 97, n. 6, p. 1038, doi. 10.1002/ana.27186

By:

Williams, McKenna E.;
Fennema‐Notestine, Christine;
Bell, Tyler R.;
Lin, Shu‐Ju;
Glatt, Stephen J.;
Kremen, William S.;
Elman, Jeremy A.

Publication type:

Article

Impaired theta and low-gamma directed information flow in the hippocampal-prefrontal circuit underlies working memory deficits in APP/PS1 mice.

Published in:

Behavioral & Brain Functions, 2025, v. 21, n. 1, p. 1, doi. 10.1186/s12993-025-00285-y

By:

Ai, Hongrui;
Zhang, Shengnan;
Si, Chengbo;
Liu, Tiaotiao;
Zheng, Xuyuan;
Tian, Xin;
Bai, Wenwen

Publication type:

Article

MRDDA: a multi-relational graph neural network for drug–disease association prediction.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06783-x

By:

Chen, Congzhou;
Zhou, Yaozheng;
Li, Yinghong;
Xu, Jin;
Li, Demin;
Wang, Lingfeng

Publication type:

Article

A Genome-wide study on the genetic and causal effects of smoking in neurodegeneration.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06688-9

By:

Chen, Chaochao;
Zhu, Shouqiang;
Zheng, Zhiying;
Ding, Xiahao;
Shi, Weihai;
Xia, Tianjiao;
Gu, Xiaoping

Publication type:

Article

Graph Spectral Analysis Using Electroencephalography in Alzheimer Disease and Frontotemporal Dementia Patients.

Published in:

International Journal of Neural Systems, 2025, v. 35, n. 9, p. 1, doi. 10.1142/S0129065725500480

By:

Bonomini, María Paula;
Ghiglioni, Eduardo;
Ríos, Noelia Belén

Publication type:

Article

Unveiling the Therapeutic Potential of Piper chaba Hunter: Computational Approaches Shed Light on Targeting Proteins in Alzheimer's Disease.

Published in:

BioMed Research International, 2025, v. 2025, p. 1, doi. 10.1155/bmri/8892801

By:

Rahi, Md. Sifat;
Rahman, Md. Shahedur;
Meem, Rima Islam;
Shimul, Md. Ebrahim Khalil;
Farnaj, Nahid;
Kabir, Md. Humaun;
Ahmed, Fee Faysal;
Parvez, Md. Anowar Khasru;
Huq, Md. Amdadul;
Kabir, Tabassum;
Harrath, Abdel Halim;
Hasan, Mahadi;
Rahman, Md. Ataur;
Siddique, Muhammad Hussnain

Publication type:

Article

Inhibitory mechanisms of amentoflavone on amyloid-β peptide aggregation revealed by replica exchange molecular dynamics.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10623-9

By:

Wu, Suxia;
Liu, Chang;
Li, Yang;
Zhang, Xiaoyu;
Han, Qianji;
Zhao, Heng;
Zhao, Kun;
Dang, Yaru;
Wang, Ruihan;
Song, Shitao

Publication type:

Article