Works about ALKYLATING agents

Results: 1995

A practical and safer model of nitrogen mustard injury in cornea.

Published in:

PLoS ONE, 2025, v. 20, n. 7, p. 1, doi. 10.1371/journal.pone.0327622

By:

Sandoval-Castellanos, Ana M.;
Ke, Yao;
Dam, Tiffany M.;
Maverakis, Emanual Michael;
Mannis, Mark J.;
Wang, Xiao-Jing;
Zhao, Min

Publication type:

Article

Enhancing temozolomide in vivo stability and efficacy through hybrid nanoconjugate approach for improved glioblastoma multiforme treatment.

Published in:

Asian Journal of Pharmaceutical Sciences, 2025, v. 20, n. 3, p. 1, doi. 10.1016/j.ajps.2025.101022

By:

Singh, Prabhjeet;
Sahel, Deepak Kumar;
Jatyan, Reena;
Bajaj, Kiran;
Mittal, Anupama;
Chitkara, Deepak

Publication type:

Article

DNA-protein cross-links emerge as major contributors to chemotherapeutic cytotoxicity at physiological equitoxic doses.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-06705-3

By:

Shoulkamy, Mahmoud I.;
Mohammed, Tareg Omer;
Ide, Hiroshi;
Nakano, Toshiaki

Publication type:

Article

Hypertrophic Cardiomyopathy and Phenocopies: New Therapies for Old Diseases—Current Evidence and Future Perspectives.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 12, p. 4228, doi. 10.3390/jcm14124228

By:

Alfarano, Maria;
Ciccarelli, Federico;
Marchionni, Giulia;
Ballatore, Federico;
Costantino, Jacopo;
Lattanzio, Antonio;
Pecci, Giulia;
Stavagna, Silvia;
Iannelli, Leonardo;
Galardo, Gioacchino;
Lavalle, Carlo;
Miraldi, Fabio;
Vizza, Carmine Dario;
Chimenti, Cristina

Publication type:

Article

Determination of DNA Hypermethylation Using Anti-cancer Drug-Temozolomide.

Published in:

Electroanalysis, 2016, v. 28, n. 5, p. 1052, doi. 10.1002/elan.201501027

By:

Topkaya, Seda Nur;
Serindere, Gokçe;
Ozder, Melike

Publication type:

Article

Electrochemical Study of the Interaction of the Alkylating Agent Busulfan with Double Strand DNA.

Published in:

Electroanalysis, 2013, v. 25, n. 11, p. 2463, doi. 10.1002/elan.201300294

By:

Radi, Abd‐Elgawad;
Nassef, Hossam M.;
Eissa, Alsayed

Publication type:

Article

Thermal behaviour of 1,2,4-triazole and 1,2,4-triazine derivatives.

Published in:

Journal of Thermal Analysis & Calorimetry, 2005, v. 81, n. 1, p. 119, doi. 10.1007/s10973-005-0754-y

By:

Sikorska-Iwan, Mariola;
Modzelewska-Banachiewicz, Bozena

Publication type:

Article

Kinetic and thermodynamic treatment of gasification process for some s-triazines.

Published in:

Journal of Thermal Analysis & Calorimetry, 2003, v. 74, n. 1, p. 121, doi. 10.1023/A:1026329820099

By:

Rodante, F.;
Vecchio, S.;
Favero, G.

Publication type:

Article

PARP inhibition suppresses the emergence of temozolomide resistance in a model system.

Published in:

Journal of Neuro-Oncology, 2020, v. 148, n. 3, p. 463, doi. 10.1007/s11060-020-03561-1

By:

Yuan, Alice L.;
Meode, Mathieu;
Tan, Melanie;
Maxwell, Lori;
Bering, Elizabeth. A.;
Pedersen, Haley;
Willms, Jacob;
Liao, Jenny;
Black, Sophie;
Cairncross, J. Gregory;
Blough, Michael D.

Publication type:

Article

G3BP1 knockdown sensitizes U87 glioblastoma cell line to Bortezomib by inhibiting stress granules assembly and potentializing apoptosis.

Published in:

Journal of Neuro-Oncology, 2019, v. 144, n. 3, p. 463, doi. 10.1007/s11060-019-03252-6

By:

Bittencourt, L. F. F.;
Negreiros-Lima, G. L.;
Sousa, L. P.;
Silva, A. G.;
Souza, I. B. S.;
Ribeiro, R. I. M. A.;
Dutra, M. F.;
Silva, R. F.;
Dias, A. C. F.;
Soriani, F. M.;
Martins, W. K.;
Barcelos, L. S.

Publication type:

Article

Letter to the editor: local alkylating chemotherapy applied immediately after 5-ALA guided resection of glioblastoma does not provide additional benefit.

Published in:

2018

By:

Roux, Alexandre;
Zanello, Marc;
Pallud, Johan

Publication type:

Letter to the Editor

Opening the ventricle during surgery diminishes survival among patients with newly diagnosed glioblastoma treated with carmustine wafers: a multi-center retrospective study.

Published in:

Journal of Neuro-Oncology, 2017, v. 134, n. 1, p. 83, doi. 10.1007/s11060-017-2488-7

By:

Sonoda, Yukihiko;
Shibahara, Ichiyo;
Matsuda, Ken-ichiro;
Saito, Ryuta;
Kawataki, Tomoyuki;
Oda, Masaya;
Sato, Yuichi;
Sadahiro, Hirokazu;
Nomura, Sadahiro;
Sasajima, Toshio;
Beppu, Takaaki;
Kanamori, Masayuki;
Sakurada, Kaori;
Kumabe, Toshihiro;
Tominaga, Teiji;
Kinouchi, Hiroyuki;
Shimizu, Hiroaki;
Ogasawara, Kuniaki;
Suzuki, Michiyasu

Publication type:

Article

Risk of severe acute liver injury among patients with brain cancer treated with temozolomide: a nested case-control study using the healthcore integrated research database.

Published in:

Journal of Neuro-Oncology, 2017, v. 134, n. 1, p. 89, doi. 10.1007/s11060-017-2489-6

By:

Desai, Vibha;
Quinlan, Scott;
Deitz, Anne;
He, Jinghua;
Holick, Crystal;
Lanes, Stephan

Publication type:

Article

Changes in PlGF and MET-HGF expressions in paired initial and recurrent glioblastoma.

Published in:

Journal of Neuro-Oncology, 2016, v. 130, n. 3, p. 431, doi. 10.1007/s11060-016-2251-5

By:

Tabouret, Emeline;
Denicolai, Emilie;
Delfino, Christine;
Graillon, Thomas;
Boucard, Celine;
Nanni, Isabelle;
Padovani, Laetitia;
Figarella-Branger, Dominique;
Chinot, Olivier

Publication type:

Article

Reevaluating stereotactic radiosurgery for glioblastoma: new potential for targeted dose-escalation.

Published in:

Journal of Neuro-Oncology, 2016, v. 130, n. 3, p. 397, doi. 10.1007/s11060-016-2270-2

By:

Yanagihara, Ted;
Saadatmand, Heva;
Wang, Tony

Publication type:

Article

Analyzing temozolomide medication errors: potentially fatal.

Published in:

Journal of Neuro-Oncology, 2014, v. 120, n. 1, p. 111, doi. 10.1007/s11060-014-1523-1

By:

Letarte, Nathalie;
Gabay, Michael;
Bressler, Linda;
Long, Katie;
Stachnik, Joan;
Villano, J.

Publication type:

Article

MGMT promoter methylation in plasma of glioma patients receiving temozolomide.

Published in:

Journal of Neuro-Oncology, 2014, v. 117, n. 2, p. 347, doi. 10.1007/s11060-014-1395-4

By:

Fiano, Valentina;
Trevisan, Morena;
Trevisan, Elisa;
Senetta, Rebecca;
Castiglione, Anna;
Sacerdote, Carlotta;
Gillio-Tos, Anna;
Marco, Laura;
Grasso, Chiara;
Magistrello, Michela;
Tondat, Fabrizio;
Rudà, Roberta;
Cassoni, Paola;
Soffietti, Riccardo;
Merletti, Franco

Publication type:

Article

Outcomes for patients with anaplastic astrocytoma treated with chemoradiation, radiation therapy alone or radiation therapy followed by chemotherapy: a retrospective review within the era of temozolomide.

Published in:

Journal of Neuro-Oncology, 2013, v. 113, n. 2, p. 305, doi. 10.1007/s11060-013-1116-4

By:

Shonka, Nicole;
Theeler, Brett;
Cahill, Daniel;
Yung, Alfred;
Smith, Lynette;
Lei, Xiudong;
Gilbert, Mark

Publication type:

Article

'One week on-one week off': efficacy and side effects of dose-intensified temozolomide chemotherapy: experiences of a single center.

Published in:

Journal of Neuro-Oncology, 2013, v. 112, n. 2, p. 209, doi. 10.1007/s11060-013-1048-z

By:

Galldiks, Norbert;
Berhorn, Theresa;
Blau, Tobias;
Dunkl, Veronika;
Fink, Gereon;
Schroeter, Michael

Publication type:

Article

The value of temozolomide in combination with radiotherapy during standard treatment for newly diagnosed glioblastoma.

Published in:

Journal of Neuro-Oncology, 2013, v. 112, n. 2, p. 277, doi. 10.1007/s11060-013-1060-3

By:

Park, Chul-Kee;
Lee, Se-Hoon;
Kim, Tae;
Choi, Seung;
Park, Sung-Hye;
Heo, Dae;
Kim, Il;
Jung, Hee-Won

Publication type:

Article

Temozolomide use in adult patients with gliosarcoma: an evolving clinical practice.

Published in:

Journal of Neuro-Oncology, 2013, v. 112, n. 1, p. 83, doi. 10.1007/s11060-012-1029-7

By:

Walker, Gary;
Gilbert, Mark;
Prabhu, Sujit;
Brown, Paul;
McAleer, Mary

Publication type:

Article

Combination of paclitaxel thermal gel depot with temozolomide and radiotherapy significantly prolongs survival in an experimental rodent glioma model.

Published in:

Journal of Neuro-Oncology, 2013, v. 111, n. 3, p. 229, doi. 10.1007/s11060-012-1014-1

By:

Vellimana, Ananth;
Recinos, Violette;
Hwang, Lee;
Fowers, Kirk;
Li, Khan;
Zhang, Yonggang;
Okonma, Saint;
Eberhart, Charles;
Brem, Henry;
Tyler, Betty

Publication type:

Article

Lack of MGMT promoter hypermethylation in hemangiopericytomas of the central nervous system.

Published in:

2012

By:

Brokinkel, Benjamin;
Peetz-Dienhart, Susanne;
Keyvani, Kathy;
Stummer, Walter;
Paulus, Werner;
Hasselblatt, Martin

Publication type:

Letter

Radiotherapy and concomitant temozolomide may improve survival of elderly patients with glioblastoma.

Published in:

Journal of Neuro-Oncology, 2012, v. 109, n. 2, p. 391, doi. 10.1007/s11060-012-0906-4

By:

Barker, Christopher;
Chang, Maria;
Chou, Joanne;
Zhang, Zhigang;
Beal, Kathryn;
Gutin, Philip;
Iwamoto, Fabio

Publication type:

Article

Efficacy of clinically relevant temozolomide dosing schemes in glioblastoma cancer stem cell lines.

Published in:

Journal of Neuro-Oncology, 2012, v. 109, n. 1, p. 45, doi. 10.1007/s11060-012-0878-4

By:

Beier, Dagmar;
Schriefer, Beate;
Brawanski, Konstantin;
Hau, Peter;
Weis, Joachim;
Schulz, Jörg;
Beier, Christoph

Publication type:

Article

Phase II trial of temozolomide for leptomeningeal metastases in patients with solid tumors.

Published in:

Journal of Neuro-Oncology, 2012, v. 109, n. 1, p. 137, doi. 10.1007/s11060-012-0879-3

By:

Segura, Pedro;
Gil, Miguel;
Balañá, Carmen;
Chacón, Ignacio;
Langa, José;
Martín, María;
Bruna, Jordi

Publication type:

Article

Dose dense 1 week on/1 week off temozolomide in recurrent glioma: a retrospective study.

Published in:

Journal of Neuro-Oncology, 2012, v. 108, n. 1, p. 195, doi. 10.1007/s11060-012-0832-5

By:

Taal, Walter;
Segers-van Rijn, Joyce;
Kros, Johan;
Heuvel, Irene;
Rijt, Carin;
Bromberg, Jacoline;
Sillevis Smitt, Peter;
Bent, Martin

Publication type:

Article

Extended adjuvant temozolomide for treatment of newly diagnosed glioblastoma multiforme.

Published in:

Journal of Neuro-Oncology, 2012, v. 108, n. 1, p. 173, doi. 10.1007/s11060-012-0826-3

By:

Roldán Urgoiti, Gloria;
Singh, Amitabh;
Easaw, Jacob

Publication type:

Article

Prospective cohort study of radiotherapy with concomitant and adjuvant temozolomide chemotherapy for glioblastoma patients with no or minimal residual enhancing tumor load after surgery.

Published in:

Journal of Neuro-Oncology, 2012, v. 108, n. 1, p. 89, doi. 10.1007/s11060-012-0798-3

By:

Stummer, Walter;
Meinel, Thomas;
Ewelt, Christian;
Martus, Peter;
Jakobs, Olga;
Felsberg, Jörg;
Reifenberger, Guido

Publication type:

Article

Initial experience with bendamustine in patients with recurrent primary central nervous system lymphoma: a case report.

Published in:

2012

By:

Renfrow, Jaclyn;
DeTroye, Alisha;
Chan, Michael;
Tatter, Stephen;
Ellis, Thomas;
McMullen, Kevin;
Johnson, Annette;
Mott, Ryan;
Lesser, Glenn

Publication type:

Report

Glioblastoma survival in the United States before and during the temozolomide era.

Published in:

Journal of Neuro-Oncology, 2012, v. 107, n. 2, p. 359, doi. 10.1007/s11060-011-0749-4

By:

Johnson, Derek;
O'Neill, Brian

Publication type:

Article

Higher topoisomerase 2 alpha gene transcript levels predict better prognosis in GBM patients receiving temozolomide chemotherapy: identification of temozolomide as a TOP2A inhibitor.

Published in:

Journal of Neuro-Oncology, 2012, v. 107, n. 2, p. 289, doi. 10.1007/s11060-011-0758-3

By:

Arivazhagan, A.;
Kumar, Durairaj;
Sagar, Vinay;
Patric, Irene;
Sridevi, S.;
Thota, Balaram;
Srividya, Mallavarapu;
Prasanna, K.;
Thennarasu, K.;
Mondal, Neelima;
Hegde, A.;
Chandramouli, B.;
Santosh, V.;
Rao, M.;
Kondaiah, P.;
Somasundaram, K.

Publication type:

Article

Hypofractionated radiotherapy with or without concurrent temozolomide in elderly patients with glioblastoma multiforme: a review of ten-year single institutional experience.

Published in:

Journal of Neuro-Oncology, 2012, v. 107, n. 2, p. 395, doi. 10.1007/s11060-011-0766-3

By:

Cao, Jeffrey;
Fisher, Barbara;
Bauman, Glenn;
Megyesi, Joseph;
Watling, Christopher;
Macdonald, David

Publication type:

Article

A phase II study of O6-benzylguanine and temozolomide in pediatric patients with recurrent or progressive high-grade gliomas and brainstem gliomas: a Pediatric Brain Tumor Consortium study.

Published in:

Journal of Neuro-Oncology, 2012, v. 106, n. 3, p. 643, doi. 10.1007/s11060-011-0709-z

By:

Warren, Katherine;
Gururangan, Sri;
Geyer, J.;
McLendon, Roger;
Poussaint, Tina;
Wallace, Dana;
Balis, Frank;
Berg, Stacey;
Packer, Roger;
Goldman, Stewart;
Minturn, Jane;
Pollack, Ian;
Boyett, James;
Kun, Larry

Publication type:

Article

Radiotherapy with concurrent and adjuvant temozolomide in children with newly diagnosed diffuse intrinsic pontine glioma.

Published in:

Journal of Neuro-Oncology, 2012, v. 106, n. 2, p. 399, doi. 10.1007/s11060-011-0681-7

By:

Chassot, Andrea;
Canale, Sandra;
Varlet, Pascale;
Puget, Stephanie;
Roujeau, Thomas;
Negretti, Laura;
Dhermain, Frederic;
Rialland, Xavier;
Raquin, Marie;
Grill, Jacques;
Dufour, Christelle

Publication type:

Article

Salvage treatment with temozolomide in refractory or relapsed primary central nervous system lymphoma and assessment of the MGMT status.

Published in:

Journal of Neuro-Oncology, 2012, v. 106, n. 1, p. 155, doi. 10.1007/s11060-011-0652-z

By:

Makino, Keishi;
Nakamura, Hideo;
Hide, Taku-ichiro;
Kuratsu, Jun-ichi

Publication type:

Article

Intravenous administration of temozolomide as a useful alternative over oral treatment with temozolomide capsules in patients with gliomas.

Published in:

2012

By:

Motomura, Kazuya;
Natsume, Atsushi;
Wakabayashi, Toshihiko

Publication type:

Letter

Prophylactic intrathecal chemotherapy in primary CNS lymphoma.

Published in:

Journal of Neuro-Oncology, 2012, v. 106, n. 1, p. 143, doi. 10.1007/s11060-011-0649-7

By:

Sierra del Rio, Monica;
Ricard, Damien;
Houillier, Caroline;
Navarro, Soledad;
Gonzalez-Aguilar, Alberto;
Idbaih, Ahmed;
Kaloshi, Gentian;
Elhallani, Soufiane;
Omuro, Antonio;
Choquet, Sylvain;
Soussain, Carole;
Hoang-Xuan, Khé

Publication type:

Article

A phase I trial of the farnesyl transferase inhibitor, SCH 66336, with temozolomide for patients with malignant glioma.

Published in:

Journal of Neuro-Oncology, 2011, v. 105, n. 3, p. 601, doi. 10.1007/s11060-011-0627-0

By:

Desjardins, Annick;
Reardon, David;
Peters, Katherine;
Threatt, Stevie;
Coan, April;
Herndon, James;
Friedman, Allan;
Friedman, Henry;
Vredenburgh, James

Publication type:

Article

Postoperative seizure in high grade glioma patients treated with BCNU wafers. A mono-institutional experience.

Published in:

Journal of Neuro-Oncology, 2011, v. 105, n. 2, p. 275, doi. 10.1007/s11060-011-0577-6

By:

Della Puppa, Alessandro;
Denaro, Luca;
Rossetto, Marta;
Ciccarino, Pietro;
Manara, Renzo;
Lombardi, Giuseppe;
Del Moro, Giulia;
Rotilio, Antonino;
d'Avella, Domenico;
Scienza, Renato

Publication type:

Article

Cediranib enhances control of wild type EGFR and EGFRvIII-expressing gliomas through potentiating temozolomide, but not through radiosensitization: implications for the clinic.

Published in:

Journal of Neuro-Oncology, 2011, v. 105, n. 2, p. 181, doi. 10.1007/s11060-011-0580-y

By:

Wachsberger, Phyllis;
Lawrence, Richard;
Liu, Yi;
Xia, Xu;
Andersen, Barbara;
Dicker, Adam

Publication type:

Article

Assessment of MGMT promoter methylation status in pleomorphic xanthoastrocytoma.

Published in:

Journal of Neuro-Oncology, 2011, v. 105, n. 2, p. 397, doi. 10.1007/s11060-011-0605-6

By:

Marucci, Gianluca;
Morandi, Luca

Publication type:

Article

Using different schedules of Temozolomide to treat low grade gliomas: systematic review of their efficacy and toxicity.

Published in:

Journal of Neuro-Oncology, 2011, v. 105, n. 2, p. 135, doi. 10.1007/s11060-011-0657-7

By:

Lashkari, Harsha;
Saso, Srdjan;
Moreno, Lucas;
Athanasiou, Thanos;
Zacharoulis, Stergios

Publication type:

Article

MGMT promoter methylation and immunoexpression in aggressive pituitary adenomas and carcinomas.

Published in:

Journal of Neuro-Oncology, 2011, v. 104, n. 3, p. 647, doi. 10.1007/s11060-011-0532-6

By:

Salehi, Fateme;
Scheithauer, Bernd;
Kros, Johann;
Lau, Queenie;
Fealey, Michael;
Erickson, Dana;
Kovacs, Kalman;
Horvath, Eva;
Lloyd, Ricardo

Publication type:

Article

Temozolomide and 13- cis retinoic acid in patients with anaplastic gliomas: a prospective single-arm monocentric phase-II study (RNOP-05).

Published in:

Journal of Neuro-Oncology, 2011, v. 104, n. 3, p. 801, doi. 10.1007/s11060-011-0548-y

By:

Grauer, Oliver;
Pascher, Christina;
Hartmann, Christian;
Zeman, Florian;
Weller, Michael;
Proescholdt, Martin;
Brawanski, Alexander;
Pietsch, Thorsten;
Wick, Wolfgang;
Bogdahn, Ulrich;
Hau, Peter

Publication type:

Article

Tissue concentration of systemically administered antineoplastic agents in human brain tumors.

Published in:

Journal of Neuro-Oncology, 2011, v. 104, n. 3, p. 629, doi. 10.1007/s11060-011-0564-y

By:

Pitz, Marshall;
Desai, Arati;
Grossman, Stuart;
Blakeley, Jaishri

Publication type:

Article

Impact of therapy on quality of life, neurocognitive function and their correlates in glioblastoma multiforme: a review.

Published in:

Journal of Neuro-Oncology, 2011, v. 104, n. 3, p. 639, doi. 10.1007/s11060-011-0565-x

By:

Henriksson, Roger;
Asklund, Thomas;
Poulsen, Hans

Publication type:

Article

Radiotherapy and temozolomide for newly diagnosed glioblastoma and anaplastic astrocytoma: validation of Radiation Therapy Oncology Group-Recursive Partitioning Analysis in the IMRT and temozolomide era.

Published in:

Journal of Neuro-Oncology, 2011, v. 104, n. 1, p. 339, doi. 10.1007/s11060-010-0499-8

By:

Paravati, Anthony;
Heron, Dwight;
Landsittel, Douglas;
Flickinger, John;
Mintz, Arlan;
Chen, Yi-Fan;
Huq, M.

Publication type:

Article

Spinal cord anaplastic oligodendroglioma with 1p deletion: report of a relapsing case treated with temozolomide.

Published in:

2011

By:

Wang, Fulin;
Qiao, Guangyu;
Lou, Xin

Publication type:

Report

Lonafarnib (SCH66336) improves the activity of temozolomide and radiation for orthotopic malignant gliomas.

Published in:

Journal of Neuro-Oncology, 2011, v. 104, n. 1, p. 179, doi. 10.1007/s11060-010-0502-4

By:

Chaponis, Deviney;
Barnes, Jessica;
Dellagatta, Jamie;
Kesari, Santosh;
Fast, Eva;
Sauvageot, Claire;
Panagrahy, Dipak;
Greene, Emily;
Ramakrishna, Naren;
Wen, Patrick;
Kung, Andrew;
Stiles, Charles;
Kieran, Mark

Publication type:

Article