Works by de Bono, Johann

Results: 104
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    Talazoparib, a Poly(ADP-ribose) Polymerase Inhibitor, for Metastatic Castration-resistant Prostate Cancer and DNA Damage Response Alterations: TALAPRO-1 Safety Analyses.

    Published in:
    Oncologist, 2022, v. 27, n. 10, p. e783, doi. 10.1093/oncolo/oyac172
    By:
    • Mehra, Niven;
    • Fizazi, Karim;
    • Bono, Johann S de;
    • Barthélémy, Philippe;
    • Dorff, Tanya;
    • Stirling, Adam;
    • Machiels, Jean-Pascal;
    • Bimbatti, Davide;
    • Kilari, Deepak;
    • Dumez, Herlinde;
    • Buttigliero, Consuelo;
    • Oort, Inge M van;
    • Castro, Elena;
    • Chen, Hsiang-Chun;
    • Santo, Nicola Di;
    • DeAnnuntis, Liza;
    • Healy, Cynthia G;
    • Scagliotti, Giorgio V
    Publication type:
    Article
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    Talazoparib, a Poly(ADP-ribose) Polymerase Inhibitor, for Metastatic Castration-resistant Prostate Cancer and DNA Damage Response Alterations: TALAPRO-1 Safety Analyses.

    Published in:
    Oncologist, 2022, v. 27, n. 9, p. e783, doi. 10.1093/oncolo/oyac172
    By:
    • Mehra, Niven;
    • Fizazi, Karim;
    • Bono, Johann S de;
    • Barthélémy, Philippe;
    • Dorff, Tanya;
    • Stirling, Adam;
    • Machiels, Jean-Pascal;
    • Bimbatti, Davide;
    • Kilari, Deepak;
    • Dumez, Herlinde;
    • Buttigliero, Consuelo;
    • Oort, Inge M van;
    • Castro, Elena;
    • Chen, Hsiang-Chun;
    • Santo, Nicola Di;
    • DeAnnuntis, Liza;
    • Healy, Cynthia G;
    • Scagliotti, Giorgio V
    Publication type:
    Article
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    A HIF-Regulated VHL-PTP1B-Src Signaling Axis Identifies a Therapeutic Target in Renal Cell Carcinoma.

    Published in:
    Science Translational Medicine, 2011, v. 3, n. 85, p. 1, doi. 10.1126/scitranslmed.3002004
    By:
    • Suwaki, Natsuko;
    • Vanhecke, Elsa;
    • Atkins, Katelyn M.;
    • Graf, Manuela;
    • Swabey, Katherine;
    • Huang, Paul;
    • Schraml, Peter;
    • Moch, Holger;
    • Cassidy, Amy Mulick;
    • Brewer, Daniel;
    • Al-Lazikani, Bissan;
    • Workman, Paul;
    • De-Bono, Johann;
    • Kaye, Stan B.;
    • Larkin, James;
    • Gore, Martin. E.;
    • Sawyers, Charles L.;
    • Nelson, Peter;
    • Beer, Tomasz M.;
    • Geng, Hao
    Publication type:
    Article
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    Phase 1 trial of the oral AKT inhibitor MK-2206 plus carboplatin/paclitaxel, docetaxel, or erlotinib in patients with advanced solid tumors.

    Published in:
    Journal of Hematology & Oncology, 2014, v. 7, n. 1, p. 3, doi. 10.1186/1756-8722-7-1
    By:
    • Rhoda Molife, L.;
    • Li Yan;
    • Vitfell-Rasmussen, Joanna;
    • Zernhelt, Adriane M.;
    • Sullivan, Daniel M.;
    • Cassier, Philippe A.;
    • Eric Chen;
    • Biondo, Andrea;
    • Tetteh, Ernestina;
    • Siu, Lillian L.;
    • Patnaik, Amita;
    • Papadopoulos, Kyriakos P.;
    • De Bono, Johann S.;
    • Tolcher, Anthony W.;
    • Minton, Susan
    Publication type:
    Article
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    Two first-in-human studies of xentuzumab, a humanised insulin-like growth factor (IGF)-neutralising antibody, in patients with advanced solid tumours.

    Published in:
    2020
    By:
    • de Bono, Johann;
    • Lin, Chia-Chi;
    • Chen, Li-Tzong;
    • Corral, Jesus;
    • Michalarea, Vasiliki;
    • Rihawi, Karim;
    • Ong, Michael;
    • Lee, Jih-Hsiang;
    • Hsu, Chih-Hung;
    • Yang, James Chih-Hsin;
    • Shiah, Her-Shyong;
    • Yen, Chia-Jui;
    • Anthoney, Alan;
    • Jove, Maria;
    • Buschke, Susanne;
    • Fuertig, René;
    • Schmid, Ulrike;
    • Goeldner, Rainer-Georg;
    • Strelkowa, Natalja;
    • Huang, Dennis Chin-Lun
    Publication type:
    journal article
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    Differential impact of RB status on E2F1 reprogramming in human cancer.

    Published in:
    2018
    By:
    • McNair, Christopher;
    • Kexin Xu;
    • Mandigo, Amy C.;
    • Benelli, Matteo;
    • Leiby, Benjamin;
    • Rodrigues, Daniel;
    • Lindberg, Johan;
    • Gronberg, Henrik;
    • Crespo, Mateus;
    • De Laere, Bram;
    • Dirix, Luc;
    • Visakorpi, Tapio;
    • Fugen Li;
    • Feng, Felix Y.;
    • de Bono, Johann;
    • Demichelis, Francesca;
    • Rubin, Mark A.;
    • Brown, Myles;
    • Knudsen, Karen E.;
    • Xu, Kexin
    Publication type:
    journal article
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    Phase II, open-label trial to assess QTcF effects, pharmacokinetics and antitumor activity of afatinib in patients with relapsed or refractory solid tumors.

    Published in:
    Cancer Chemotherapy & Pharmacology, 2013, v. 72, n. 6, p. 1213, doi. 10.1007/s00280-013-2286-7
    By:
    • Molife, L. Rhoda;
    • Rudman, Sarah M.;
    • Alam, Salma;
    • Tan, Daniel S.-W.;
    • Kristeleit, Hartmut;
    • Middleton, Gary;
    • Propper, David;
    • Bent, Liz;
    • Stopfer, Peter;
    • Uttenreuther-Fischer, Martina;
    • Wallenstein, Gudrun;
    • de Bono, Johann;
    • Spicer, James
    Publication type:
    Article
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    Phase I and pharmacokinetic study of cisplatin and troxacitabine administered intravenously every 28 days in patients with advanced solid malignancies.

    Published in:
    Cancer Chemotherapy & Pharmacology, 2009, v. 65, n. 1, p. 167, doi. 10.1007/s00280-009-1020-y
    By:
    • Chia-Chi Lin;
    • Beeram, Muralidhar;
    • Rowinsky, Eric K.;
    • Takimoto, Chris H.;
    • Ng, Chee M.;
    • Geyer Jr., Charles E.;
    • Denis, Louis J.;
    • De Bono, Johann S.;
    • Hao, Desiree;
    • Tolcher, Anthony W.;
    • Rha, Sun-Young;
    • Jolivet, Jacques;
    • Patnaik, Amita
    Publication type:
    Article
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    Phase 1 Study of Molibresib (GSK525762), a Bromodomain and Extra-Terminal Domain Protein Inhibitor, in NUT Carcinoma and Other Solid Tumors.

    Published in:
    JNCI Cancer Spectrum, 2020, v. 4, n. 2, p. 1, doi. 10.1093/jncics/pkz093
    By:
    • Piha-Paul, Sarina A;
    • Hann, Christine L;
    • French, Christopher A;
    • Cousin, Sophie;
    • Braña, Irene;
    • Cassier, Phillippe A;
    • Moreno, Victor;
    • Bono, Johann S de;
    • Harward, Sara Duckworth;
    • Ferron-Brady, Geraldine;
    • Barbash, Olena;
    • Wyce, Anastasia;
    • Wu, Yuehui;
    • Horner, Thierry;
    • Annan, Meg;
    • Parr, Nigel J;
    • Prinjha, Rabinder K;
    • Carpenter, Christopher L;
    • Hilton, John;
    • Hong, David S
    Publication type:
    Article
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    Comparative Survival of Asian and White Metastatic Castration-Resistant Prostate Cancer Men Treated With Docetaxel.

    Published in:
    JNCI Cancer Spectrum, 2020, v. 4, n. 2, p. 1, doi. 10.1093/jncics/pkaa003
    By:
    • Halabi, Susan;
    • Dutta, Sandipan;
    • Tangen, Catherine M;
    • Rosenthal, Mark;
    • Petrylak, Daniel P;
    • Thompson, Ian M;
    • Chi, Kim N;
    • Bono, Johann S De;
    • Araujo, John C;
    • Logothetis, Christopher;
    • Eisenberger, Mario A;
    • Quinn, David I;
    • Fizazi, Karim;
    • Morris, Michael J;
    • Higano, Celestia S;
    • Tannock, Ian F;
    • Small, Eric J;
    • Kelly, William Kevin
    Publication type:
    Article
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    Exploring the Impact of Treatment Switching on Overall Survival from the PROfound Study in Homologous Recombination Repair (HRR)-Mutated Metastatic Castration-Resistant Prostate Cancer (mCRPC).

    Published in:
    Targeted Oncology, 2021, v. 16, n. 5, p. 613, doi. 10.1007/s11523-021-00837-y
    By:
    • Evans, Rachel;
    • Hawkins, Neil;
    • Dequen-O'Byrne, Pascale;
    • McCrea, Charles;
    • Muston, Dominic;
    • Gresty, Christopher;
    • Ghate, Sameer R.;
    • Fan, Lin;
    • Hettle, Robert;
    • Abrams, Keith R.;
    • de Bono, Johann;
    • Hussain, Maha;
    • Agarwal, Neeraj
    Publication type:
    Article
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    Flexible trial design in practice - stopping arms for lack-of-benefit and adding research arms mid-trial in STAMPEDE: a multi-arm multi-stage randomized controlled trial.

    Published in:
    Trials, 2012, v. 13, n. 1, p. 168, doi. 10.1186/1745-6215-13-168
    By:
    • Sydes, Matthew R.;
    • Parmar, Mahesh K. B.;
    • Mason, Malcolm D.;
    • Clarke, Noel W.;
    • Amos, Claire;
    • Anderson, John;
    • de Bono, Johann;
    • Dearnaley, David P.;
    • Dwyer, John;
    • Green, Charlene;
    • Jovic, Gordana;
    • Ritchie, Alastair W. S.;
    • Russell, J. Martin;
    • Sanders, Karen;
    • Thalmann, George;
    • James, Nicholas D.
    Publication type:
    Article
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    Correlation analyses of radiographic progression‐free survival with clinical and health‐related quality of life outcomes in metastatic castration‐resistant prostate cancer: Analysis of the phase 3 VISION trial.

    Published in:
    Cancer (0008543X), 2024, v. 130, n. 20, p. 3426, doi. 10.1002/cncr.35438
    By:
    • Morris, Michael J.;
    • de Bono, Johann;
    • Nagarajah, James;
    • Sartor, Oliver;
    • Wei, Xiao X.;
    • Nordquist, Luke T.;
    • Koshkin, Vadim S.;
    • Chi, Kim N.;
    • Krause, Bernd J.;
    • Herrmann, Ken;
    • Rahbar, Kambiz;
    • Vickers, Adrian;
    • Mirante, Osvaldo;
    • Ghouse, Ray;
    • Fizazi, Karim;
    • Tagawa, Scott T.
    Publication type:
    Article
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    Clinical activity of CC‐90011, an oral, potent, and reversible LSD1 inhibitor, in advanced malignancies.

    Published in:
    Cancer (0008543X), 2022, v. 128, n. 17, p. 3185, doi. 10.1002/cncr.34366
    By:
    • Hollebecque, Antoine;
    • Salvagni, Stefania;
    • Plummer, Ruth;
    • Niccoli, Patricia;
    • Capdevila, Jaume;
    • Curigliano, Giuseppe;
    • Moreno, Victor;
    • de Braud, Filippo;
    • de Villambrosia, Sonia Gonzalez;
    • Martin‐Romano, Patricia;
    • Baudin, Eric;
    • Arias, Marina;
    • de Alvaro, Juan;
    • Parra‐Palau, Josep L.;
    • Sánchez‐Pérez, Tania;
    • Aronchik, Ida;
    • Filvaroff, Ellen H.;
    • Lamba, Manisha;
    • Nikolova, Zariana;
    • de Bono, Johann S.
    Publication type:
    Article
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    Tumor clone dynamics in lethal prostate cancer.

    Published in:
    Science Translational Medicine, 2014, v. 6, n. 254, p. 1, doi. 10.1126/scitranslmed.3009448
    By:
    • Carreira, Suzanne;
    • Romanel, Alessandro;
    • Goodall, Jane;
    • Grist, Emily;
    • Ferraldeschi, Roberta;
    • Miranda, Susana;
    • Prandi, Davide;
    • Lorente, David;
    • Frenel, Jean-Sebastien;
    • Pezaro, Carmel;
    • Omlin, Aurelius;
    • Rodrigues, Daniel Nava;
    • Flohr, Penelope;
    • Tunariu, Nina;
    • de Bono, Johann S.;
    • Demichelis, Francesca;
    • Attard, Gerhardt
    Publication type:
    Article
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    A streamlined workflow for single-cells genome-wide copy-number profiling by low-pass sequencing of LM-PCR whole-genome amplification products.

    Published in:
    PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0193689
    By:
    • Ferrarini, Alberto;
    • Forcato, Claudio;
    • Buson, Genny;
    • Tononi, Paola;
    • del Monaco, Valentina;
    • Terracciano, Mario;
    • Bolognesi, Chiara;
    • Fontana, Francesca;
    • Medoro, Gianni;
    • Neves, Rui;
    • Möhlendick, Birte;
    • Rihawi, Karim;
    • Ardizzoni, Andrea;
    • Sumanasuriya, Semini;
    • Flohr, Penny;
    • Lambros, Maryou;
    • de Bono, Johann;
    • Stoecklein, Nikolas H.;
    • Manaresi, Nicolò
    Publication type:
    Article